#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q2M3C7	uniprotkb:Q9NYA1	intact:EBI-1803914|uniprotkb:Q68DA3|uniprotkb:Q68DR8|uniprotkb:Q9C0I5|ensembl:ENSP00000375909	intact:EBI-985303|uniprotkb:Q8N632|ensembl:ENSP00000376285|ensembl:ENSP00000440970|ensembl:ENSP00000465726|uniprotkb:Q9HD92|uniprotkb:Q9NY70|uniprotkb:Q9NYL3|uniprotkb:Q96GK1	psi-mi:spkap_human(display_long)|uniprotkb:SPHKAP(gene name)|psi-mi:SPHKAP(display_short)|uniprotkb:KIAA1678(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SPHK1-interactor and AKAP domain-containing protein(gene name synonym)|uniprotkb:Sphingosine kinase type 1-interacting protein(gene name synonym)	psi-mi:sphk1_human(display_long)|uniprotkb:Acetyltransferase SPHK1(gene name synonym)|uniprotkb:SK1(gene name synonym)|uniprotkb:SPHK(gene name synonym)|uniprotkb:SPHK1(gene name)|psi-mi:SPHK1(display_short)|uniprotkb:SPK(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lacana et al. (2002)	pubmed:12080051|imex:IM-19118	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1803938|imex:IM-19118-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001136116.1|refseq:NP_085126.2|ensembl:ENSG00000153820(gene)|ensembl:ENST00000392056(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0051018"(protein kinase A binding)|interpro:IPR008382(A-kinase anchor 110 kDa)|interpro:IPR018292	ensembl:ENSG00000176170(gene)|ensembl:ENST00000392496(transcript)|ensembl:ENST00000545180(transcript)|ensembl:ENST00000592299(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001568"(blood vessel development)|go:"GO:0001727"(lipid kinase activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006473"(protein acetylation)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006670"(sphingosine metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007420"(brain development)|go:"GO:0008289"(lipid binding)|go:"GO:0008481"(sphinganine kinase activity)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0017050"(D-erythro-sphingosine kinase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038036"(sphingosine-1-phosphate receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046521"(sphingoid catabolic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0098793"(presynapse)|go:"GO:0150077"(regulation of neuroinflammatory response)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903978"(regulation of microglial cell activation)|go:"GO:1905364"(regulation of endosomal vesicle fusion)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|mint:Q9NYA1|rcsb pdb:3VZB|rcsb pdb:3VZC|rcsb pdb:3VZD|rcsb pdb:4L02|rcsb pdb:4V24|reactome:R-HSA-1660661|reactome:R-HSA-390471|reactome:R-HSA-5218921|reactome:R-HSA-9009391|refseq:XP_005257823.1|refseq:NP_001136073.1|refseq:NP_001136074.1|refseq:NP_068807.2|refseq:NP_892010.2	-	-	-	figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/08/18	2014/10/16	rogid:L8SUcxrVCXDDfYx9iVgiBsQhHeM9606	rogid:gD4CFoO6CgCmdD9x5nBwAFY4d+49606	intact-crc:BFD6011DECA455F2|rigid:OcNz97zJYcXh2w3vGoMK2+dvIXU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q2M3C7	uniprotkb:Q9NYA1	intact:EBI-1803914|uniprotkb:Q68DA3|uniprotkb:Q68DR8|uniprotkb:Q9C0I5|ensembl:ENSP00000375909	intact:EBI-985303|uniprotkb:Q8N632|ensembl:ENSP00000376285|ensembl:ENSP00000440970|ensembl:ENSP00000465726|uniprotkb:Q9HD92|uniprotkb:Q9NY70|uniprotkb:Q9NYL3|uniprotkb:Q96GK1	psi-mi:spkap_human(display_long)|uniprotkb:SPHKAP(gene name)|psi-mi:SPHKAP(display_short)|uniprotkb:KIAA1678(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SPHK1-interactor and AKAP domain-containing protein(gene name synonym)|uniprotkb:Sphingosine kinase type 1-interacting protein(gene name synonym)	psi-mi:sphk1_human(display_long)|uniprotkb:Acetyltransferase SPHK1(gene name synonym)|uniprotkb:SK1(gene name synonym)|uniprotkb:SPHK(gene name synonym)|uniprotkb:SPHK1(gene name)|psi-mi:SPHK1(display_short)|uniprotkb:SPK(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lacana et al. (2002)	pubmed:12080051|imex:IM-19118	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1803953|imex:IM-19118-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001136116.1|refseq:NP_085126.2|ensembl:ENSG00000153820(gene)|ensembl:ENST00000392056(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0051018"(protein kinase A binding)|interpro:IPR008382(A-kinase anchor 110 kDa)|interpro:IPR018292	ensembl:ENSG00000176170(gene)|ensembl:ENST00000392496(transcript)|ensembl:ENST00000545180(transcript)|ensembl:ENST00000592299(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001568"(blood vessel development)|go:"GO:0001727"(lipid kinase activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006473"(protein acetylation)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006670"(sphingosine metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007420"(brain development)|go:"GO:0008289"(lipid binding)|go:"GO:0008481"(sphinganine kinase activity)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0017050"(D-erythro-sphingosine kinase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038036"(sphingosine-1-phosphate receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046521"(sphingoid catabolic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0098793"(presynapse)|go:"GO:0150077"(regulation of neuroinflammatory response)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903978"(regulation of microglial cell activation)|go:"GO:1905364"(regulation of endosomal vesicle fusion)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|mint:Q9NYA1|rcsb pdb:3VZB|rcsb pdb:3VZC|rcsb pdb:3VZD|rcsb pdb:4L02|rcsb pdb:4V24|reactome:R-HSA-1660661|reactome:R-HSA-390471|reactome:R-HSA-5218921|reactome:R-HSA-9009391|refseq:XP_005257823.1|refseq:NP_001136073.1|refseq:NP_001136074.1|refseq:NP_068807.2|refseq:NP_892010.2	-	-	-	figure legend:3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/08/18	2014/10/16	rogid:L8SUcxrVCXDDfYx9iVgiBsQhHeM9606	rogid:gD4CFoO6CgCmdD9x5nBwAFY4d+49606	intact-crc:B00C167CE01AF77B|rigid:OcNz97zJYcXh2w3vGoMK2+dvIXU	false	3'-phospho-L-histidine:?-?|3h radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q2M3C7	uniprotkb:Q9NYA1	intact:EBI-1803914|uniprotkb:Q68DA3|uniprotkb:Q68DR8|uniprotkb:Q9C0I5|ensembl:ENSP00000375909	intact:EBI-985303|uniprotkb:Q8N632|ensembl:ENSP00000376285|ensembl:ENSP00000440970|ensembl:ENSP00000465726|uniprotkb:Q9HD92|uniprotkb:Q9NY70|uniprotkb:Q9NYL3|uniprotkb:Q96GK1	psi-mi:spkap_human(display_long)|uniprotkb:SPHKAP(gene name)|psi-mi:SPHKAP(display_short)|uniprotkb:KIAA1678(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SPHK1-interactor and AKAP domain-containing protein(gene name synonym)|uniprotkb:Sphingosine kinase type 1-interacting protein(gene name synonym)	psi-mi:sphk1_human(display_long)|uniprotkb:Acetyltransferase SPHK1(gene name synonym)|uniprotkb:SK1(gene name synonym)|uniprotkb:SPHK(gene name synonym)|uniprotkb:SPHK1(gene name)|psi-mi:SPHK1(display_short)|uniprotkb:SPK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lacana et al. (2002)	pubmed:12080051|imex:IM-19118	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1804000|imex:IM-19118-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001136116.1|refseq:NP_085126.2|ensembl:ENSG00000153820(gene)|ensembl:ENST00000392056(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0051018"(protein kinase A binding)|interpro:IPR008382(A-kinase anchor 110 kDa)|interpro:IPR018292	ensembl:ENSG00000176170(gene)|ensembl:ENST00000392496(transcript)|ensembl:ENST00000545180(transcript)|ensembl:ENST00000592299(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001568"(blood vessel development)|go:"GO:0001727"(lipid kinase activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006473"(protein acetylation)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006670"(sphingosine metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007420"(brain development)|go:"GO:0008289"(lipid binding)|go:"GO:0008481"(sphinganine kinase activity)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0017050"(D-erythro-sphingosine kinase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038036"(sphingosine-1-phosphate receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046521"(sphingoid catabolic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0098793"(presynapse)|go:"GO:0150077"(regulation of neuroinflammatory response)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903978"(regulation of microglial cell activation)|go:"GO:1905364"(regulation of endosomal vesicle fusion)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|mint:Q9NYA1|rcsb pdb:3VZB|rcsb pdb:3VZC|rcsb pdb:3VZD|rcsb pdb:4L02|rcsb pdb:4V24|reactome:R-HSA-1660661|reactome:R-HSA-390471|reactome:R-HSA-5218921|reactome:R-HSA-9009391|refseq:XP_005257823.1|refseq:NP_001136073.1|refseq:NP_001136074.1|refseq:NP_068807.2|refseq:NP_892010.2	-	-	-	figure legend:3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/08/18	2014/10/16	rogid:L8SUcxrVCXDDfYx9iVgiBsQhHeM9606	rogid:gD4CFoO6CgCmdD9x5nBwAFY4d+49606	intact-crc:BC89C73B11E0AC3A|rigid:OcNz97zJYcXh2w3vGoMK2+dvIXU	false	3'-phospho-L-histidine:?-?|3h radiolabel:?-?	tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q2M3C7	uniprotkb:Q9NYA1	intact:EBI-1803914|uniprotkb:Q68DA3|uniprotkb:Q68DR8|uniprotkb:Q9C0I5|ensembl:ENSP00000375909	intact:EBI-985303|uniprotkb:Q8N632|ensembl:ENSP00000376285|ensembl:ENSP00000440970|ensembl:ENSP00000465726|uniprotkb:Q9HD92|uniprotkb:Q9NY70|uniprotkb:Q9NYL3|uniprotkb:Q96GK1	psi-mi:spkap_human(display_long)|uniprotkb:SPHKAP(gene name)|psi-mi:SPHKAP(display_short)|uniprotkb:KIAA1678(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SPHK1-interactor and AKAP domain-containing protein(gene name synonym)|uniprotkb:Sphingosine kinase type 1-interacting protein(gene name synonym)	psi-mi:sphk1_human(display_long)|uniprotkb:Acetyltransferase SPHK1(gene name synonym)|uniprotkb:SK1(gene name synonym)|uniprotkb:SPHK(gene name synonym)|uniprotkb:SPHK1(gene name)|psi-mi:SPHK1(display_short)|uniprotkb:SPK(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Lacana et al. (2002)	pubmed:12080051|imex:IM-19118	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1804034|imex:IM-19118-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001136116.1|refseq:NP_085126.2|ensembl:ENSG00000153820(gene)|ensembl:ENST00000392056(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0051018"(protein kinase A binding)|interpro:IPR008382(A-kinase anchor 110 kDa)|interpro:IPR018292	ensembl:ENSG00000176170(gene)|ensembl:ENST00000392496(transcript)|ensembl:ENST00000545180(transcript)|ensembl:ENST00000592299(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001568"(blood vessel development)|go:"GO:0001727"(lipid kinase activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006473"(protein acetylation)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0006670"(sphingosine metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007420"(brain development)|go:"GO:0008289"(lipid binding)|go:"GO:0008481"(sphinganine kinase activity)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0017050"(D-erythro-sphingosine kinase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038036"(sphingosine-1-phosphate receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046521"(sphingoid catabolic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0098793"(presynapse)|go:"GO:0150077"(regulation of neuroinflammatory response)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903978"(regulation of microglial cell activation)|go:"GO:1905364"(regulation of endosomal vesicle fusion)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|mint:Q9NYA1|rcsb pdb:3VZB|rcsb pdb:3VZC|rcsb pdb:3VZD|rcsb pdb:4L02|rcsb pdb:4V24|reactome:R-HSA-1660661|reactome:R-HSA-390471|reactome:R-HSA-5218921|reactome:R-HSA-9009391|refseq:XP_005257823.1|refseq:NP_001136073.1|refseq:NP_001136074.1|refseq:NP_068807.2|refseq:NP_892010.2	go:"GO:0005737"(cytoplasm)	-	-	figure legend:5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells)	-	2008/08/18	2014/10/16	rogid:L8SUcxrVCXDDfYx9iVgiBsQhHeM9606	rogid:gD4CFoO6CgCmdD9x5nBwAFY4d+49606	intact-crc:38C1179C072972D7|rigid:OcNz97zJYcXh2w3vGoMK2+dvIXU	false	ha tag:?-?	tag:n-n	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)