#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q06132 uniprotkb:P32383 intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C intact:EBI-13485|uniprotkb:D6W3A2|ensemblfungi:YPL268W psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name) psi-mi:plc1_yeast(display_long)|uniprotkb:PLC1(gene name)|psi-mi:PLC1(display_short)|uniprotkb:Phosphoinositide phospholipase C(gene name synonym)|uniprotkb:Phospholipase C-1(gene name synonym)|uniprotkb:YPL268W(locus name) psi-mi:"MI:0018"(two hybrid) Lin et al. (2002) pubmed:12073033 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1792823 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold) refseq:NP_015055.1|sgd:S000006189|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR017946|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|ensemblfungi:YPL268W(gene)|ensemblfungi:YPL268W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0032958"(inositol phosphate biosynthetic process)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|reactome:R-SCE-112043|reactome:R-SCE-1855204|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-434316|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR037755|mint:P32383|interpro:IPR035892 - crc64:8EEFDB8258407FF3 - figure legend:No figure taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/16 2014/10/16 rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292 rogid:E3fBblnaa1w/+ezJKNhAKN1dabg559292 intact-crc:F95E875B4FF6456A|rigid:KeqMPHuTfPd0tm4g6KToxvfupcc false sufficient binding region:624-726 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P32383 uniprotkb:Q06132 intact:EBI-13485|uniprotkb:D6W3A2|ensemblfungi:YPL268W intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C psi-mi:plc1_yeast(display_long)|uniprotkb:PLC1(gene name)|psi-mi:PLC1(display_short)|uniprotkb:Phosphoinositide phospholipase C(gene name synonym)|uniprotkb:Phospholipase C-1(gene name synonym)|uniprotkb:YPL268W(locus name) psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name) psi-mi:"MI:0018"(two hybrid) Lin et al. (2002) pubmed:12073033 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1792844 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015055.1|sgd:S000006189|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR017946|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|ensemblfungi:YPL268W(gene)|ensemblfungi:YPL268W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0032958"(inositol phosphate biosynthetic process)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|reactome:R-SCE-112043|reactome:R-SCE-1855204|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-434316|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR037755|mint:P32383|interpro:IPR035892 refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold) - - crc64:8EEFDB8258407FF3 figure legend:Fig. 1A taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/16 2014/10/16 rogid:E3fBblnaa1w/+ezJKNhAKN1dabg559292 rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292 intact-crc:F6962A24D0D67C7C|rigid:KeqMPHuTfPd0tm4g6KToxvfupcc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32383 uniprotkb:Q06132 intact:EBI-13485|uniprotkb:D6W3A2|ensemblfungi:YPL268W intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C psi-mi:plc1_yeast(display_long)|uniprotkb:PLC1(gene name)|psi-mi:PLC1(display_short)|uniprotkb:Phosphoinositide phospholipase C(gene name synonym)|uniprotkb:Phospholipase C-1(gene name synonym)|uniprotkb:YPL268W(locus name) psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name) psi-mi:"MI:0096"(pull down) Lin et al. (2002) pubmed:12073033 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1792872 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015055.1|sgd:S000006189|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR017946|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|ensemblfungi:YPL268W(gene)|ensemblfungi:YPL268W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0032958"(inositol phosphate biosynthetic process)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|reactome:R-SCE-112043|reactome:R-SCE-1855204|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-434316|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR037755|mint:P32383|interpro:IPR035892 refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold) - - crc64:8EEFDB8258407FF3 figure legend:Fig. 1B taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/07/16 2014/10/16 rogid:E3fBblnaa1w/+ezJKNhAKN1dabg559292 rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292 intact-crc:A7F4585E40B5682D|rigid:KeqMPHuTfPd0tm4g6KToxvfupcc false ha tag:c-c binding-associated region:491-726|glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)