#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0AEJ4 uniprotkb:P0AA16 intact:EBI-1121750|uniprotkb:P02933|uniprotkb:Q2M769|ensemblbacteria:AAC76429|ensemblbacteria:BAE77887 intact:EBI-369514|uniprotkb:O31133|uniprotkb:P03025|uniprotkb:P08981|uniprotkb:P41405|uniprotkb:Q2M770|ensemblbacteria:AAC76430|ensemblbacteria:BAE77886 psi-mi:envz_ecoli(display_long)|uniprotkb:Osmolarity sensor protein EnvZ(gene name synonym)|uniprotkb:envZ(gene name)|psi-mi:envZ(display_short)|uniprotkb:ompB(gene name synonym)|uniprotkb:perA(gene name synonym)|uniprotkb:tpo(gene name synonym)|uniprotkb:b3404(locus name)|uniprotkb:JW3367(locus name) psi-mi:ompr_ecoli(display_long)|uniprotkb:ompR(gene name)|psi-mi:ompR(display_short)|uniprotkb:ompB(gene name synonym)|uniprotkb:kmt(gene name synonym)|uniprotkb:b3405(locus name)|uniprotkb:JW3368(locus name)|uniprotkb:Transcriptional regulatory protein OmpR(gene name synonym) psi-mi:"MI:0096"(pull down) Cai et al. (1990) pubmed:11973328|imex:IM-20179 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2116569|imex:IM-20179-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_001253696.1|ensemblbacteria:AAC76429(transcript)|ensemblbacteria:b3404(gene)|ensemblbacteria:BAE77887(gene)|ensemblbacteria:BAE77887(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016310"(phosphorylation)|go:"GO:0018106"(peptidyl-histidine phosphorylation)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1BXD|rcsb pdb:1JOY|rcsb pdb:1NJV|rcsb pdb:3ZCC|rcsb pdb:3ZRV|rcsb pdb:3ZRW|rcsb pdb:3ZRX|rcsb pdb:4CTI|rcsb pdb:4KP4|rcsb pdb:5B1N|rcsb pdb:5B1O|rcsb pdb:5XGA|refseq:NP_417863.1|dip:DIP-48357N refseq:WP_001157751.1|refseq:NP_417864.1|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR011006(CheY-like)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR036388|interpro:IPR039420|rcsb pdb:1ODD|rcsb pdb:1OPC|rcsb pdb:2JPB|go:"GO:0000160"(phosphorelay signal transduction system)|ensemblbacteria:AAC76430(transcript)|ensemblbacteria:b3405(gene)|ensemblbacteria:BAE77886(gene)|ensemblbacteria:BAE77886(transcript)|go:"GO:0000156"(phosphorelay response regulator activity)|dip:DIP-31859N - - - figure legend:3,4|kinetic_conditions:Kd values in the presence of ADP plus Mg2+ and ADPNP plus Mg2+ were found to be 1.17 microMoles and 1.23 microMoles|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/11/20 2014/10/16 rogid:9sboPYQKBefVhBDHcDk7cBmYrZ883333 rogid:j6McYahD+zVzWvsuN1eZlmWYOFg83333 intact-crc:4F23E80ECCC50919|rigid:Rzx/G33iNwWEnw6MNQ0uniL+Stc false - his tag:?-? 1 1 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)