#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0ABM1	uniprotkb:P69490	intact:EBI-2123469|uniprotkb:P33929|uniprotkb:Q2MAP4|ensemblbacteria:AAC75259|ensemblbacteria:BAE76662	intact:EBI-1128007|uniprotkb:P33928|uniprotkb:Q2MAP6|ensemblbacteria:AAC75257|ensemblbacteria:BAE76660	psi-mi:ccmc_ecoli(display_long)|uniprotkb:ccmC(gene name)|psi-mi:ccmC(display_short)|uniprotkb:yejT(gene name synonym)|uniprotkb:yejU(gene name synonym)|uniprotkb:Cytochrome c-type biogenesis protein CcmC(gene name synonym)|uniprotkb:b2199(locus name)|uniprotkb:JW2187(locus name)	psi-mi:ccme_ecoli(display_long)|uniprotkb:ccmE(gene name)|psi-mi:ccmE(display_short)|uniprotkb:b2197(locus name)|uniprotkb:JW2185(locus name)|uniprotkb:yejS(gene name synonym)|uniprotkb:Cytochrome c maturation protein E(gene name synonym)|uniprotkb:Heme chaperone CcmE(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ren et al. (2002)	pubmed:11744735|imex:IM-19098|mint:MINT-5214949	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2123486|imex:IM-19098-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001295447.1|refseq:NP_416703.1|interpro:IPR002541(Cytochrome c assembly protein)|interpro:IPR003557(Cytochrome c-type biogenesis protein CcmC)|ensemblbacteria:AAC75259(transcript)|ensemblbacteria:b2199(gene)|ensemblbacteria:BAE76662(gene)|ensemblbacteria:BAE76662(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0017004"(cytochrome complex assembly)|go:"GO:0020037"(heme binding)	refseq:NP_416701.1|refseq:WP_001026418.1|ensemblbacteria:AAC75257(transcript)|ensemblbacteria:b2197(gene)|ensemblbacteria:BAE76660(gene)|ensemblbacteria:BAE76660(transcript)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018063"(cytochrome c-heme linkage)|go:"GO:0020037"(heme binding)|go:"GO:0031237"(intrinsic component of periplasmic side of plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR004329(CcmE/CycJ protein)|interpro:IPR036127|rcsb pdb:1SR3|dip:DIP-9255N	-	-	-	figure legend:Table III|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/12/03	2014/10/16	rogid:0ibTZO7/qV52xbtiWcE7oXm5drc83333	rogid:VWG+HZkkWjdNJy7D6G46VLlR9dc83333	intact-crc:59703C90B38391B8|rigid:CjCvvA9zNTftnmKnDKzmt34FKo4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P0ABM1	uniprotkb:P69490	intact:EBI-2123469|uniprotkb:P33929|uniprotkb:Q2MAP4|ensemblbacteria:AAC75259|ensemblbacteria:BAE76662	intact:EBI-1128007|uniprotkb:P33928|uniprotkb:Q2MAP6|ensemblbacteria:AAC75257|ensemblbacteria:BAE76660	psi-mi:ccmc_ecoli(display_long)|uniprotkb:ccmC(gene name)|psi-mi:ccmC(display_short)|uniprotkb:yejT(gene name synonym)|uniprotkb:yejU(gene name synonym)|uniprotkb:Cytochrome c-type biogenesis protein CcmC(gene name synonym)|uniprotkb:b2199(locus name)|uniprotkb:JW2187(locus name)	psi-mi:ccme_ecoli(display_long)|uniprotkb:ccmE(gene name)|psi-mi:ccmE(display_short)|uniprotkb:b2197(locus name)|uniprotkb:JW2185(locus name)|uniprotkb:yejS(gene name synonym)|uniprotkb:Cytochrome c maturation protein E(gene name synonym)|uniprotkb:Heme chaperone CcmE(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ren et al. (2002)	pubmed:11744735|imex:IM-19098|mint:MINT-5214949	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2123490|imex:IM-19098-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001295447.1|refseq:NP_416703.1|interpro:IPR002541(Cytochrome c assembly protein)|interpro:IPR003557(Cytochrome c-type biogenesis protein CcmC)|ensemblbacteria:AAC75259(transcript)|ensemblbacteria:b2199(gene)|ensemblbacteria:BAE76662(gene)|ensemblbacteria:BAE76662(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0017004"(cytochrome complex assembly)|go:"GO:0020037"(heme binding)	refseq:NP_416701.1|refseq:WP_001026418.1|ensemblbacteria:AAC75257(transcript)|ensemblbacteria:b2197(gene)|ensemblbacteria:BAE76660(gene)|ensemblbacteria:BAE76660(transcript)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018063"(cytochrome c-heme linkage)|go:"GO:0020037"(heme binding)|go:"GO:0031237"(intrinsic component of periplasmic side of plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR004329(CcmE/CycJ protein)|interpro:IPR036127|rcsb pdb:1SR3|dip:DIP-9255N	-	-	-	figure legend:Table III|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/12/03	2014/10/16	rogid:0ibTZO7/qV52xbtiWcE7oXm5drc83333	rogid:VWG+HZkkWjdNJy7D6G46VLlR9dc83333	intact-crc:B99EBE7E51AFFDD8|rigid:CjCvvA9zNTftnmKnDKzmt34FKo4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P33927	uniprotkb:P69490	intact:EBI-763370|uniprotkb:Q2MAP7|ensemblbacteria:AAC75256|ensemblbacteria:BAE76659	intact:EBI-1128007|uniprotkb:P33928|uniprotkb:Q2MAP6|ensemblbacteria:AAC75257|ensemblbacteria:BAE76660	psi-mi:ccmf_ecoli(display_long)|uniprotkb:yejR(gene name synonym)|uniprotkb:ccmF(gene name)|psi-mi:ccmF(display_short)|uniprotkb:b2196(locus name)|uniprotkb:JW2184(locus name)	psi-mi:ccme_ecoli(display_long)|uniprotkb:ccmE(gene name)|psi-mi:ccmE(display_short)|uniprotkb:b2197(locus name)|uniprotkb:JW2185(locus name)|uniprotkb:yejS(gene name synonym)|uniprotkb:Cytochrome c maturation protein E(gene name synonym)|uniprotkb:Heme chaperone CcmE(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ren et al. (2002)	pubmed:11744735|imex:IM-19098|mint:MINT-5214949	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2123494|imex:IM-19098-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000982447.1|refseq:NP_416700.1|dip:DIP-9256N|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0018063"(cytochrome c-heme linkage)|go:"GO:0020037"(heme binding)|interpro:IPR002541(Cytochrome c assembly protein)|interpro:IPR003567(Cytochrome c-type biogenesis protein)|interpro:IPR003568(Cytochrome c-type biogenesis protein CcmF)|interpro:IPR032523|go:"GO:0005886"(plasma membrane)|ensemblbacteria:AAC75256(transcript)|ensemblbacteria:b2196(gene)|ensemblbacteria:BAE76659(gene)|ensemblbacteria:BAE76659(transcript)	refseq:NP_416701.1|refseq:WP_001026418.1|ensemblbacteria:AAC75257(transcript)|ensemblbacteria:b2197(gene)|ensemblbacteria:BAE76660(gene)|ensemblbacteria:BAE76660(transcript)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018063"(cytochrome c-heme linkage)|go:"GO:0020037"(heme binding)|go:"GO:0031237"(intrinsic component of periplasmic side of plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR004329(CcmE/CycJ protein)|interpro:IPR036127|rcsb pdb:1SR3|dip:DIP-9255N	-	-	-	comment:The interaction is not affected by the Ala-173, Ala-261, Ala-303 point mutations or the tryptophan-rich motif mutant in ccmF.|figure legend:Table III and Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/12/03	2014/10/16	rogid:4NBcGbpZ1kJYsTmpIM+Zs096Tko83333	rogid:VWG+HZkkWjdNJy7D6G46VLlR9dc83333	intact-crc:67463FDF549557B2|rigid:bpaw2cnf33eeXUDzDs5k26aPgkU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P0ABM9	uniprotkb:P33927	intact:EBI-560309|uniprotkb:P33925|uniprotkb:Q2MAP9|ensemblbacteria:AAC75254|ensemblbacteria:BAE76657	intact:EBI-763370|uniprotkb:Q2MAP7|ensemblbacteria:AAC75256|ensemblbacteria:BAE76659	psi-mi:ccmh_ecoli(display_long)|uniprotkb:yejP(gene name synonym)|uniprotkb:ccmH(gene name)|psi-mi:ccmH(display_short)|uniprotkb:b2194(locus name)|uniprotkb:JW2182(locus name)	psi-mi:ccmf_ecoli(display_long)|uniprotkb:yejR(gene name synonym)|uniprotkb:ccmF(gene name)|psi-mi:ccmF(display_short)|uniprotkb:b2196(locus name)|uniprotkb:JW2184(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ren et al. (2002)	pubmed:11744735|imex:IM-19098|mint:MINT-5214949	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2123499|imex:IM-19098-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_416698.1|refseq:WP_001211575.1|dip:DIP-48146N|ensemblbacteria:AAC75254(transcript)|ensemblbacteria:b2194(gene)|ensemblbacteria:BAE76657(gene)|ensemblbacteria:BAE76657(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017004"(cytochrome complex assembly)|go:"GO:0018378"(cytochrome c-heme linkage via heme-L-cysteine)|go:"GO:0031237"(intrinsic component of periplasmic side of plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR005616(Cytochrome C biogenesis protein)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR038297	refseq:WP_000982447.1|refseq:NP_416700.1|dip:DIP-9256N|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0018063"(cytochrome c-heme linkage)|go:"GO:0020037"(heme binding)|interpro:IPR002541(Cytochrome c assembly protein)|interpro:IPR003567(Cytochrome c-type biogenesis protein)|interpro:IPR003568(Cytochrome c-type biogenesis protein CcmF)|interpro:IPR032523|go:"GO:0005886"(plasma membrane)|ensemblbacteria:AAC75256(transcript)|ensemblbacteria:b2196(gene)|ensemblbacteria:BAE76659(gene)|ensemblbacteria:BAE76659(transcript)	-	-	-	comment:The interaction is not affected by the Ala-173, Ala-261, Ala-303 point mutations or the tryptophan-rich motif mutant in ccmF.|figure legend:Table III and Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/12/03	2014/10/16	rogid:KRNOM3TL/nqaz/ibfY73jFpKmaY83333	rogid:4NBcGbpZ1kJYsTmpIM+Zs096Tko83333	intact-crc:872141E158F430C5|rigid:tman433XQFIDXA7SFORWaDauWJg	false	his tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)