#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O94307	uniprotkb:P10506	intact:EBI-2042611|ensemblfungi:"SPBC215.02.1:pep"	intact:EBI-2042633|ensemblfungi:"SPAC1D4.13.1:pep"	psi-mi:pfd5_schpo(display_long)|uniprotkb:bob1(gene name)|psi-mi:bob1(display_short)|uniprotkb:Byr1-binding protein Bob1(gene name synonym)|uniprotkb:SPBC215.02(orf name)	psi-mi:byr1_schpo(display_long)|uniprotkb:byr1(gene name)|psi-mi:byr1(display_short)|uniprotkb:ste1(gene name synonym)|uniprotkb:MAPK kinase(gene name synonym)|uniprotkb:SPAC1D4.13(orf name)	psi-mi:"MI:0018"(two hybrid)	Henkel et al. (2001)	pubmed:11683500|imex:IM-20164	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2042610|imex:IM-20164-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_596679.1|interpro:IPR011599(Prefoldin alpha subunit)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|ensemblfungi:SPBC215.02(gene)|ensemblfungi:SPBC215.02.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032153"(cell division site)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051286"(cell tip)	refseq:NP_593026.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-110056|reactome:R-SPO-112411|reactome:R-SPO-445144|reactome:R-SPO-5674135|reactome:R-SPO-5674499|ensemblfungi:SPAC1D4.13(gene)|ensemblfungi:SPAC1D4.13.1(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0032153"(cell division site)|go:"GO:0034307"(regulation of ascospore formation)|go:"GO:0051286"(cell tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	-	-	figure legend:Figure 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/06	2014/10/16	rogid:iMLoDpPooKt0PGAnperk755vkLk284812	rogid:0RpqQ2/gWFNcHh1kDr1wbL22w6U284812	intact-crc:E5337AF21172A995|rigid:V2Rk695AbbFKDL4DqL3TIX/UFyg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94307	uniprotkb:P10506	intact:EBI-2042611|ensemblfungi:"SPBC215.02.1:pep"	intact:EBI-2042633|ensemblfungi:"SPAC1D4.13.1:pep"	psi-mi:pfd5_schpo(display_long)|uniprotkb:bob1(gene name)|psi-mi:bob1(display_short)|uniprotkb:Byr1-binding protein Bob1(gene name synonym)|uniprotkb:SPBC215.02(orf name)	psi-mi:byr1_schpo(display_long)|uniprotkb:byr1(gene name)|psi-mi:byr1(display_short)|uniprotkb:ste1(gene name synonym)|uniprotkb:MAPK kinase(gene name synonym)|uniprotkb:SPAC1D4.13(orf name)	psi-mi:"MI:0096"(pull down)	Henkel et al. (2001)	pubmed:11683500|imex:IM-20164	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2042664|imex:IM-20164-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_596679.1|interpro:IPR011599(Prefoldin alpha subunit)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|ensemblfungi:SPBC215.02(gene)|ensemblfungi:SPBC215.02.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032153"(cell division site)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051286"(cell tip)	refseq:NP_593026.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-110056|reactome:R-SPO-112411|reactome:R-SPO-445144|reactome:R-SPO-5674135|reactome:R-SPO-5674499|ensemblfungi:SPAC1D4.13(gene)|ensemblfungi:SPAC1D4.13.1(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0032153"(cell division site)|go:"GO:0034307"(regulation of ascospore formation)|go:"GO:0051286"(cell tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	-	-	figure legend:Figure 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2008/11/06	2014/10/16	rogid:iMLoDpPooKt0PGAnperk755vkLk284812	rogid:0RpqQ2/gWFNcHh1kDr1wbL22w6U284812	intact-crc:87F6091B4B4CB4FF|rigid:V2Rk695AbbFKDL4DqL3TIX/UFyg	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P27638	uniprotkb:P10506	intact:EBI-2104356|ensemblfungi:"SPAC31G5.09c.1:pep"	intact:EBI-2042633|ensemblfungi:"SPAC1D4.13.1:pep"	psi-mi:spk1_schpo(display_long)|uniprotkb:spk1(gene name)|psi-mi:spk1(display_short)|uniprotkb:SPAC31G5.09c(orf name)	psi-mi:byr1_schpo(display_long)|uniprotkb:byr1(gene name)|psi-mi:byr1(display_short)|uniprotkb:ste1(gene name synonym)|uniprotkb:MAPK kinase(gene name synonym)|uniprotkb:SPAC1D4.13(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Henkel et al. (2001)	pubmed:11683500|imex:IM-20164	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2104336|imex:IM-20164-3	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SPO-112409|reactome:R-SPO-198753|reactome:R-SPO-202670|reactome:R-SPO-3371453|reactome:R-SPO-5673001|reactome:R-SPO-110056|reactome:R-SPO-112411|reactome:R-SPO-445144|reactome:R-SPO-5674135|reactome:R-SPO-5674499|reactome:R-SPO-170968|refseq:NP_594009.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-2559582|reactome:R-SPO-375165|reactome:R-SPO-5668599|reactome:R-SPO-5675221|reactome:R-SPO-5687128|reactome:R-SPO-881907|reactome:R-SPO-6798695|reactome:R-SPO-450341|reactome:R-SPO-111995|reactome:R-SPO-437239|reactome:R-SPO-9634635|ensemblfungi:SPAC31G5.09c(gene)|ensemblfungi:SPAC31G5.09c.1(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	refseq:NP_593026.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-110056|reactome:R-SPO-112411|reactome:R-SPO-445144|reactome:R-SPO-5674135|reactome:R-SPO-5674499|ensemblfungi:SPAC1D4.13(gene)|ensemblfungi:SPAC1D4.13.1(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0032153"(cell division site)|go:"GO:0034307"(regulation of ascospore formation)|go:"GO:0051286"(cell tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	figure legend:Figure 4A and 4B|comment:GST-Byr1 phosphorylated CM-Spk1 in these assays, but did not phosphorylate CM-Bob1|resulting-ptm:Phosphorylation of Spk1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2008/11/06	2014/10/16	rogid:qH6Zs+UeAarxVUH1p86FeFXkpcY284812	rogid:0RpqQ2/gWFNcHh1kDr1wbL22w6U284812	intact-crc:7DEE4D10E1A3A8D0|rigid:8MlRQSfpvpIOFStjiuWMkhy6t8k	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)