#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q54K32 uniprotkb:Q54HG2 intact:EBI-1808670|uniprotkb:O15815|uniprotkb:P90531|intact:EBI-1997884|ensemblprotists:EAL63601 intact:EBI-1810875|uniprotkb:O15813|ensemblprotists:EAL62673 psi-mi:rgaa_dicdi(display_long)|uniprotkb:rgaA(gene name)|psi-mi:rgaA(display_short)|uniprotkb:DDB_G0287585(orf name)|uniprotkb:DG1029(gene name synonym)|uniprotkb:rasGAP1(gene name synonym)|uniprotkb:Developmental gene 1029 protein(gene name synonym) psi-mi:ctxa_dicdi(display_long)|uniprotkb:ctxA(gene name)|psi-mi:ctxA(display_short)|uniprotkb:Cortexillin I(gene name synonym)|uniprotkb:DDB_G0289483(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Faix et al. (2001) pubmed:11447112 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1810874 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dictybase:DDB_G0287585|go:"GO:0007165"(signal transduction)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030587"(sorocarp development)|go:"GO:0031149"(sorocarp stalk cell differentiation)|go:"GO:0031154"(culmination involved in sorocarp development)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031255"(lateral part of motile cell)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036360"(sorocarp stalk morphogenesis)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045180"(basal cortex)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0140509"(epithelium-like organization)|go:"GO:1903665"(negative regulation of asexual reproduction)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-DDI-5626467|reactome:R-DDI-5674135|reactome:R-DDI-6798695|reactome:R-DDI-9013149|reactome:R-DDI-9013404|reactome:R-DDI-9013420|reactome:R-DDI-9013424|refseq:XP_637132.1|ensemblprotists:DDB_G0287585(gene)|ensemblprotists:EAL63601(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex) dictybase:DDB_G0289483|dip:DIP-52435N|ensemblprotists:DDB_G0289483(gene)|ensemblprotists:EAL62673(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0009617"(response to bacterium)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031255"(lateral part of motile cell)|go:"GO:0031982"(vesicle)|go:"GO:0032060"(bleb assembly)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0036360"(sorocarp stalk morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045178"(basal part of cell)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051639"(actin filament network formation)|go:"GO:1905345"(protein localization to cleavage furrow)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015383(Cortexillin I, coiled coil)|interpro:IPR036872|rcsb pdb:1D7M|rcsb pdb:4J4A|refseq:XP_636175.1 - - - figure legend:Fig 1B taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") - 2008/09/12 2014/10/16 rogid:4XjyZq0wzx6CBoAiZ+82m3JQrWg44689 rogid:nR4dqp8ukLUBbsx2YGw59RErL3k44689 intact-crc:FAB07CE40AD70F2F|rigid:/AFgFTDNLWkNC8gO+/fiCigae9s false - green fluorescent protein tag:n-n - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00899 uniprotkb:P34144 intact:EBI-1811101|uniprotkb:Q55DP3|ensemblprotists:EAL71920 intact:EBI-1808643|uniprotkb:Q54YK6|uniprotkb:Q9GPU0|ensemblprotists:EAL68107 psi-mi:gapa_dicdi(display_long)|uniprotkb:gapA(gene name)|psi-mi:gapA(display_short)|uniprotkb:DDB_G0269140(orf name)|uniprotkb:IQGAP-related protein gapA(gene name synonym) psi-mi:rac1a_dicdi(display_long)|uniprotkb:rac1A(gene name)|psi-mi:rac1A(display_short)|uniprotkb:DDB_G0277869(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Faix et al. (2001) pubmed:11447112 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1811115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dictybase:DDB_G0269140|ensemblprotists:DDB_G0269140(gene)|ensemblprotists:EAL71920(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051015"(actin filament binding)|go:"GO:0051225"(spindle assembly)|go:"GO:1905345"(protein localization to cleavage furrow)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-DDI-5626467|reactome:R-DDI-6798695|reactome:R-DDI-9013149|refseq:XP_646088.1 dictybase:DDB_G0277869|ensemblprotists:DDB_G0277869(gene)|ensemblprotists:EAL68107(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005811"(lipid droplet)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1902412"(regulation of mitotic cytokinesis)|go:"GO:1904269"(cell leading edge cell cortex)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DDI-193648|reactome:R-DDI-2029482|reactome:R-DDI-389359|reactome:R-DDI-3928662|reactome:R-DDI-445144|reactome:R-DDI-5626467|reactome:R-DDI-5627123|reactome:R-DDI-5663213|reactome:R-DDI-5668599|reactome:R-DDI-5687128|reactome:R-DDI-6798695|reactome:R-DDI-9013149|reactome:R-DDI-9013404|reactome:R-DDI-9013407|reactome:R-DDI-9013418|reactome:R-DDI-9013420|reactome:R-DDI-9013422|reactome:R-DDI-9013424|reactome:R-DDI-9706019|reactome:R-DDI-983231|refseq:XP_642196.1 - - - figure legend:Fig 3D taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") - 2008/09/12 2014/10/16 rogid:1EaX6ToyZ324fUJ4P9hvjyaIaas44689 rogid:kBmhXb5GJdKRREo3zRPPLA/xf2c44689 intact-crc:10E634DA28572A73|rigid:5Ovn7d5X4LFV44X9/b8UcMMmEVk false - green fluorescent protein tag:n-n|mutation disrupting interaction:12-12 - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q54K32 uniprotkb:Q54HG2 intact:EBI-1808670|uniprotkb:O15815|uniprotkb:P90531|intact:EBI-1997884|ensemblprotists:EAL63601 intact:EBI-1810875|uniprotkb:O15813|ensemblprotists:EAL62673 psi-mi:rgaa_dicdi(display_long)|uniprotkb:rgaA(gene name)|psi-mi:rgaA(display_short)|uniprotkb:DDB_G0287585(orf name)|uniprotkb:DG1029(gene name synonym)|uniprotkb:rasGAP1(gene name synonym)|uniprotkb:Developmental gene 1029 protein(gene name synonym) psi-mi:ctxa_dicdi(display_long)|uniprotkb:ctxA(gene name)|psi-mi:ctxA(display_short)|uniprotkb:Cortexillin I(gene name synonym)|uniprotkb:DDB_G0289483(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Faix et al. (2001) pubmed:11447112 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1810915 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dictybase:DDB_G0287585|go:"GO:0007165"(signal transduction)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030587"(sorocarp development)|go:"GO:0031149"(sorocarp stalk cell differentiation)|go:"GO:0031154"(culmination involved in sorocarp development)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031255"(lateral part of motile cell)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036360"(sorocarp stalk morphogenesis)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045180"(basal cortex)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0140509"(epithelium-like organization)|go:"GO:1903665"(negative regulation of asexual reproduction)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-DDI-5626467|reactome:R-DDI-5674135|reactome:R-DDI-6798695|reactome:R-DDI-9013149|reactome:R-DDI-9013404|reactome:R-DDI-9013420|reactome:R-DDI-9013424|refseq:XP_637132.1|ensemblprotists:DDB_G0287585(gene)|ensemblprotists:EAL63601(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex) dictybase:DDB_G0289483|dip:DIP-52435N|ensemblprotists:DDB_G0289483(gene)|ensemblprotists:EAL62673(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0009617"(response to bacterium)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031255"(lateral part of motile cell)|go:"GO:0031982"(vesicle)|go:"GO:0032060"(bleb assembly)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0036360"(sorocarp stalk morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045178"(basal part of cell)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051639"(actin filament network formation)|go:"GO:1905345"(protein localization to cleavage furrow)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015383(Cortexillin I, coiled coil)|interpro:IPR036872|rcsb pdb:1D7M|rcsb pdb:4J4A|refseq:XP_636175.1 - - - figure legend:Fig 1C, 1F, 1J taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") - 2008/09/12 2014/10/16 rogid:4XjyZq0wzx6CBoAiZ+82m3JQrWg44689 rogid:nR4dqp8ukLUBbsx2YGw59RErL3k44689 intact-crc:7AFC06D81D1E419C|rigid:/AFgFTDNLWkNC8gO+/fiCigae9s false - sufficient binding region:352-435|green fluorescent protein tag:n-n - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P34144 uniprotkb:Q54K32 intact:EBI-1808643|uniprotkb:Q54YK6|uniprotkb:Q9GPU0|ensemblprotists:EAL68107 intact:EBI-1808670|uniprotkb:O15815|uniprotkb:P90531|intact:EBI-1997884|ensemblprotists:EAL63601 psi-mi:rac1a_dicdi(display_long)|uniprotkb:rac1A(gene name)|psi-mi:rac1A(display_short)|uniprotkb:DDB_G0277869(orf name) psi-mi:rgaa_dicdi(display_long)|uniprotkb:rgaA(gene name)|psi-mi:rgaA(display_short)|uniprotkb:DDB_G0287585(orf name)|uniprotkb:DG1029(gene name synonym)|uniprotkb:rasGAP1(gene name synonym)|uniprotkb:Developmental gene 1029 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Faix et al. (2001) pubmed:11447112 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1810975 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dictybase:DDB_G0277869|ensemblprotists:DDB_G0277869(gene)|ensemblprotists:EAL68107(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005811"(lipid droplet)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1902412"(regulation of mitotic cytokinesis)|go:"GO:1904269"(cell leading edge cell cortex)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DDI-193648|reactome:R-DDI-2029482|reactome:R-DDI-389359|reactome:R-DDI-3928662|reactome:R-DDI-445144|reactome:R-DDI-5626467|reactome:R-DDI-5627123|reactome:R-DDI-5663213|reactome:R-DDI-5668599|reactome:R-DDI-5687128|reactome:R-DDI-6798695|reactome:R-DDI-9013149|reactome:R-DDI-9013404|reactome:R-DDI-9013407|reactome:R-DDI-9013418|reactome:R-DDI-9013420|reactome:R-DDI-9013422|reactome:R-DDI-9013424|reactome:R-DDI-9706019|reactome:R-DDI-983231|refseq:XP_642196.1 dictybase:DDB_G0287585|go:"GO:0007165"(signal transduction)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030587"(sorocarp development)|go:"GO:0031149"(sorocarp stalk cell differentiation)|go:"GO:0031154"(culmination involved in sorocarp development)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031255"(lateral part of motile cell)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036360"(sorocarp stalk morphogenesis)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045180"(basal cortex)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0140509"(epithelium-like organization)|go:"GO:1903665"(negative regulation of asexual reproduction)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-DDI-5626467|reactome:R-DDI-5674135|reactome:R-DDI-6798695|reactome:R-DDI-9013149|reactome:R-DDI-9013404|reactome:R-DDI-9013420|reactome:R-DDI-9013424|refseq:XP_637132.1|ensemblprotists:DDB_G0287585(gene)|ensemblprotists:EAL63601(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex) - - - figure legend:Fig 3A, 4B|stimulant:Interaction between rac1A and rgaA is stimulated by GTP-gamma-S.|stimulant:Interaction between rac1A and ctxA requires either rgaA or gapA.|stimulant:Interaction between rac1A and ctxB requires either rgaA or gapA. taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/09/12 2014/10/16 rogid:kBmhXb5GJdKRREo3zRPPLA/xf2c44689 rogid:4XjyZq0wzx6CBoAiZ+82m3JQrWg44689 intact-crc:E74BFA47C53CB279|rigid:pkpW9SrbMO7JlnDpVyC+WD7PgPo false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P34144 uniprotkb:Q550R2 intact:EBI-1808643|uniprotkb:Q54YK6|uniprotkb:Q9GPU0|ensemblprotists:EAL68107 intact:EBI-1811057|uniprotkb:O15814|uniprotkb:Q8MNG7|ensemblprotists:EAL68948 psi-mi:rac1a_dicdi(display_long)|uniprotkb:rac1A(gene name)|psi-mi:rac1A(display_short)|uniprotkb:DDB_G0277869(orf name) psi-mi:ctxb_dicdi(display_long)|uniprotkb:ctxB(gene name)|psi-mi:ctxB(display_short)|uniprotkb:Cortexillin II(gene name synonym)|uniprotkb:DDB_G0276893(orf name) psi-mi:"MI:0096"(pull down) Faix et al. (2001) pubmed:11447112 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1810975 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dictybase:DDB_G0277869|ensemblprotists:DDB_G0277869(gene)|ensemblprotists:EAL68107(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005811"(lipid droplet)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1902412"(regulation of mitotic cytokinesis)|go:"GO:1904269"(cell leading edge cell cortex)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DDI-193648|reactome:R-DDI-2029482|reactome:R-DDI-389359|reactome:R-DDI-3928662|reactome:R-DDI-445144|reactome:R-DDI-5626467|reactome:R-DDI-5627123|reactome:R-DDI-5663213|reactome:R-DDI-5668599|reactome:R-DDI-5687128|reactome:R-DDI-6798695|reactome:R-DDI-9013149|reactome:R-DDI-9013404|reactome:R-DDI-9013407|reactome:R-DDI-9013418|reactome:R-DDI-9013420|reactome:R-DDI-9013422|reactome:R-DDI-9013424|reactome:R-DDI-9706019|reactome:R-DDI-983231|refseq:XP_642196.1 dictybase:DDB_G0276893|ensemblprotists:DDB_G0276893(gene)|ensemblprotists:EAL68948(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030587"(sorocarp development)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031254"(cell trailing edge)|go:"GO:0032060"(bleb assembly)|go:"GO:0032154"(cleavage furrow)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015383(Cortexillin I, coiled coil)|interpro:IPR036872|reactome:R-DDI-6807878|refseq:XP_642870.1 - - - figure legend:Fig 3A, 4B|stimulant:Interaction between rac1A and rgaA is stimulated by GTP-gamma-S.|stimulant:Interaction between rac1A and ctxA requires either rgaA or gapA.|stimulant:Interaction between rac1A and ctxB requires either rgaA or gapA. taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/09/12 2014/10/16 rogid:kBmhXb5GJdKRREo3zRPPLA/xf2c44689 rogid:n83KIrdrZXMDCdb/kIBUaoAdaNs44689 intact-crc:E74BFA47C53CB279|rigid:pkpW9SrbMO7JlnDpVyC+WD7PgPo false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P34144 uniprotkb:Q54HG2 intact:EBI-1808643|uniprotkb:Q54YK6|uniprotkb:Q9GPU0|ensemblprotists:EAL68107 intact:EBI-1810875|uniprotkb:O15813|ensemblprotists:EAL62673 psi-mi:rac1a_dicdi(display_long)|uniprotkb:rac1A(gene name)|psi-mi:rac1A(display_short)|uniprotkb:DDB_G0277869(orf name) psi-mi:ctxa_dicdi(display_long)|uniprotkb:ctxA(gene name)|psi-mi:ctxA(display_short)|uniprotkb:Cortexillin I(gene name synonym)|uniprotkb:DDB_G0289483(orf name) psi-mi:"MI:0096"(pull down) Faix et al. (2001) pubmed:11447112 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1810975 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dictybase:DDB_G0277869|ensemblprotists:DDB_G0277869(gene)|ensemblprotists:EAL68107(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005811"(lipid droplet)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1902412"(regulation of mitotic cytokinesis)|go:"GO:1904269"(cell leading edge cell cortex)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DDI-193648|reactome:R-DDI-2029482|reactome:R-DDI-389359|reactome:R-DDI-3928662|reactome:R-DDI-445144|reactome:R-DDI-5626467|reactome:R-DDI-5627123|reactome:R-DDI-5663213|reactome:R-DDI-5668599|reactome:R-DDI-5687128|reactome:R-DDI-6798695|reactome:R-DDI-9013149|reactome:R-DDI-9013404|reactome:R-DDI-9013407|reactome:R-DDI-9013418|reactome:R-DDI-9013420|reactome:R-DDI-9013422|reactome:R-DDI-9013424|reactome:R-DDI-9706019|reactome:R-DDI-983231|refseq:XP_642196.1 dictybase:DDB_G0289483|dip:DIP-52435N|ensemblprotists:DDB_G0289483(gene)|ensemblprotists:EAL62673(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0009617"(response to bacterium)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031255"(lateral part of motile cell)|go:"GO:0031982"(vesicle)|go:"GO:0032060"(bleb assembly)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0036360"(sorocarp stalk morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045178"(basal part of cell)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051639"(actin filament network formation)|go:"GO:1905345"(protein localization to cleavage furrow)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015383(Cortexillin I, coiled coil)|interpro:IPR036872|rcsb pdb:1D7M|rcsb pdb:4J4A|refseq:XP_636175.1 - - - figure legend:Fig 3A, 4B|stimulant:Interaction between rac1A and rgaA is stimulated by GTP-gamma-S.|stimulant:Interaction between rac1A and ctxA requires either rgaA or gapA.|stimulant:Interaction between rac1A and ctxB requires either rgaA or gapA. taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/09/12 2014/10/16 rogid:kBmhXb5GJdKRREo3zRPPLA/xf2c44689 rogid:nR4dqp8ukLUBbsx2YGw59RErL3k44689 intact-crc:E74BFA47C53CB279|rigid:pkpW9SrbMO7JlnDpVyC+WD7PgPo false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P34144 uniprotkb:Q54K32 intact:EBI-1808643|uniprotkb:Q54YK6|uniprotkb:Q9GPU0|ensemblprotists:EAL68107 intact:EBI-1808670|uniprotkb:O15815|uniprotkb:P90531|intact:EBI-1997884|ensemblprotists:EAL63601 psi-mi:rac1a_dicdi(display_long)|uniprotkb:rac1A(gene name)|psi-mi:rac1A(display_short)|uniprotkb:DDB_G0277869(orf name) psi-mi:rgaa_dicdi(display_long)|uniprotkb:rgaA(gene name)|psi-mi:rgaA(display_short)|uniprotkb:DDB_G0287585(orf name)|uniprotkb:DG1029(gene name synonym)|uniprotkb:rasGAP1(gene name synonym)|uniprotkb:Developmental gene 1029 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Faix et al. (2001) pubmed:11447112 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1810997 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dictybase:DDB_G0277869|ensemblprotists:DDB_G0277869(gene)|ensemblprotists:EAL68107(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005811"(lipid droplet)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1902412"(regulation of mitotic cytokinesis)|go:"GO:1904269"(cell leading edge cell cortex)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DDI-193648|reactome:R-DDI-2029482|reactome:R-DDI-389359|reactome:R-DDI-3928662|reactome:R-DDI-445144|reactome:R-DDI-5626467|reactome:R-DDI-5627123|reactome:R-DDI-5663213|reactome:R-DDI-5668599|reactome:R-DDI-5687128|reactome:R-DDI-6798695|reactome:R-DDI-9013149|reactome:R-DDI-9013404|reactome:R-DDI-9013407|reactome:R-DDI-9013418|reactome:R-DDI-9013420|reactome:R-DDI-9013422|reactome:R-DDI-9013424|reactome:R-DDI-9706019|reactome:R-DDI-983231|refseq:XP_642196.1 dictybase:DDB_G0287585|go:"GO:0007165"(signal transduction)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030587"(sorocarp development)|go:"GO:0031149"(sorocarp stalk cell differentiation)|go:"GO:0031154"(culmination involved in sorocarp development)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031255"(lateral part of motile cell)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036360"(sorocarp stalk morphogenesis)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045180"(basal cortex)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0140509"(epithelium-like organization)|go:"GO:1903665"(negative regulation of asexual reproduction)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-DDI-5626467|reactome:R-DDI-5674135|reactome:R-DDI-6798695|reactome:R-DDI-9013149|reactome:R-DDI-9013404|reactome:R-DDI-9013420|reactome:R-DDI-9013424|refseq:XP_637132.1|ensemblprotists:DDB_G0287585(gene)|ensemblprotists:EAL63601(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex) - - - figure legend:Fig 3B|stimulant:Interaction between rac1A and rgaA is stimulated by GTP-gamma-S.|stimulant:Interaction between rac1A and ctxA requires rgaA and is stimulated by GTP-gamma-S. taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/09/12 2014/10/16 rogid:kBmhXb5GJdKRREo3zRPPLA/xf2c44689 rogid:4XjyZq0wzx6CBoAiZ+82m3JQrWg44689 intact-crc:684A959CD3C4E8BE|rigid:6W7bFkkIH4jaqBu5WUVlenArwAQ false glutathione s tranferase tag:n-n his tag:n-n - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P34144 uniprotkb:Q54HG2 intact:EBI-1808643|uniprotkb:Q54YK6|uniprotkb:Q9GPU0|ensemblprotists:EAL68107 intact:EBI-1810875|uniprotkb:O15813|ensemblprotists:EAL62673 psi-mi:rac1a_dicdi(display_long)|uniprotkb:rac1A(gene name)|psi-mi:rac1A(display_short)|uniprotkb:DDB_G0277869(orf name) psi-mi:ctxa_dicdi(display_long)|uniprotkb:ctxA(gene name)|psi-mi:ctxA(display_short)|uniprotkb:Cortexillin I(gene name synonym)|uniprotkb:DDB_G0289483(orf name) psi-mi:"MI:0096"(pull down) Faix et al. (2001) pubmed:11447112 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1810997 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dictybase:DDB_G0277869|ensemblprotists:DDB_G0277869(gene)|ensemblprotists:EAL68107(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005811"(lipid droplet)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1902412"(regulation of mitotic cytokinesis)|go:"GO:1904269"(cell leading edge cell cortex)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DDI-193648|reactome:R-DDI-2029482|reactome:R-DDI-389359|reactome:R-DDI-3928662|reactome:R-DDI-445144|reactome:R-DDI-5626467|reactome:R-DDI-5627123|reactome:R-DDI-5663213|reactome:R-DDI-5668599|reactome:R-DDI-5687128|reactome:R-DDI-6798695|reactome:R-DDI-9013149|reactome:R-DDI-9013404|reactome:R-DDI-9013407|reactome:R-DDI-9013418|reactome:R-DDI-9013420|reactome:R-DDI-9013422|reactome:R-DDI-9013424|reactome:R-DDI-9706019|reactome:R-DDI-983231|refseq:XP_642196.1 dictybase:DDB_G0289483|dip:DIP-52435N|ensemblprotists:DDB_G0289483(gene)|ensemblprotists:EAL62673(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0009617"(response to bacterium)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031255"(lateral part of motile cell)|go:"GO:0031982"(vesicle)|go:"GO:0032060"(bleb assembly)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0036360"(sorocarp stalk morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045178"(basal part of cell)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051639"(actin filament network formation)|go:"GO:1905345"(protein localization to cleavage furrow)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015383(Cortexillin I, coiled coil)|interpro:IPR036872|rcsb pdb:1D7M|rcsb pdb:4J4A|refseq:XP_636175.1 - - - figure legend:Fig 3B|stimulant:Interaction between rac1A and rgaA is stimulated by GTP-gamma-S.|stimulant:Interaction between rac1A and ctxA requires rgaA and is stimulated by GTP-gamma-S. taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/09/12 2014/10/16 rogid:kBmhXb5GJdKRREo3zRPPLA/xf2c44689 rogid:nR4dqp8ukLUBbsx2YGw59RErL3k44689 intact-crc:684A959CD3C4E8BE|rigid:6W7bFkkIH4jaqBu5WUVlenArwAQ false glutathione s tranferase tag:n-n his tag:n-n - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q550R2 uniprotkb:Q54HG2 intact:EBI-1811057|uniprotkb:O15814|uniprotkb:Q8MNG7|ensemblprotists:EAL68948 intact:EBI-1810875|uniprotkb:O15813|ensemblprotists:EAL62673 psi-mi:ctxb_dicdi(display_long)|uniprotkb:ctxB(gene name)|psi-mi:ctxB(display_short)|uniprotkb:Cortexillin II(gene name synonym)|uniprotkb:DDB_G0276893(orf name) psi-mi:ctxa_dicdi(display_long)|uniprotkb:ctxA(gene name)|psi-mi:ctxA(display_short)|uniprotkb:Cortexillin I(gene name synonym)|uniprotkb:DDB_G0289483(orf name) psi-mi:"MI:0096"(pull down) Faix et al. (2001) pubmed:11447112 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1811212 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dictybase:DDB_G0276893|ensemblprotists:DDB_G0276893(gene)|ensemblprotists:EAL68948(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030587"(sorocarp development)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031254"(cell trailing edge)|go:"GO:0032060"(bleb assembly)|go:"GO:0032154"(cleavage furrow)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015383(Cortexillin I, coiled coil)|interpro:IPR036872|reactome:R-DDI-6807878|refseq:XP_642870.1 dictybase:DDB_G0289483|dip:DIP-52435N|ensemblprotists:DDB_G0289483(gene)|ensemblprotists:EAL62673(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0009617"(response to bacterium)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031255"(lateral part of motile cell)|go:"GO:0031982"(vesicle)|go:"GO:0032060"(bleb assembly)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0036360"(sorocarp stalk morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045178"(basal part of cell)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051639"(actin filament network formation)|go:"GO:1905345"(protein localization to cleavage furrow)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015383(Cortexillin I, coiled coil)|interpro:IPR036872|rcsb pdb:1D7M|rcsb pdb:4J4A|refseq:XP_636175.1 - - - figure legend:Fig 5E taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/09/12 2014/10/16 rogid:n83KIrdrZXMDCdb/kIBUaoAdaNs44689 rogid:nR4dqp8ukLUBbsx2YGw59RErL3k44689 intact-crc:60B6075C4C124E5E|rigid:jVc2m9Pxv/uiDzN1a7gJ4KjETQA false his tag:n-n - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P34144 uniprotkb:Q54HG2 intact:EBI-1808643|uniprotkb:Q54YK6|uniprotkb:Q9GPU0|ensemblprotists:EAL68107 intact:EBI-1810875|uniprotkb:O15813|ensemblprotists:EAL62673 psi-mi:rac1a_dicdi(display_long)|uniprotkb:rac1A(gene name)|psi-mi:rac1A(display_short)|uniprotkb:DDB_G0277869(orf name) psi-mi:ctxa_dicdi(display_long)|uniprotkb:ctxA(gene name)|psi-mi:ctxA(display_short)|uniprotkb:Cortexillin I(gene name synonym)|uniprotkb:DDB_G0289483(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Faix et al. (2001) pubmed:11447112 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1811047 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dictybase:DDB_G0277869|ensemblprotists:DDB_G0277869(gene)|ensemblprotists:EAL68107(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005811"(lipid droplet)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1902412"(regulation of mitotic cytokinesis)|go:"GO:1904269"(cell leading edge cell cortex)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DDI-193648|reactome:R-DDI-2029482|reactome:R-DDI-389359|reactome:R-DDI-3928662|reactome:R-DDI-445144|reactome:R-DDI-5626467|reactome:R-DDI-5627123|reactome:R-DDI-5663213|reactome:R-DDI-5668599|reactome:R-DDI-5687128|reactome:R-DDI-6798695|reactome:R-DDI-9013149|reactome:R-DDI-9013404|reactome:R-DDI-9013407|reactome:R-DDI-9013418|reactome:R-DDI-9013420|reactome:R-DDI-9013422|reactome:R-DDI-9013424|reactome:R-DDI-9706019|reactome:R-DDI-983231|refseq:XP_642196.1 dictybase:DDB_G0289483|dip:DIP-52435N|ensemblprotists:DDB_G0289483(gene)|ensemblprotists:EAL62673(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0009617"(response to bacterium)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031255"(lateral part of motile cell)|go:"GO:0031982"(vesicle)|go:"GO:0032060"(bleb assembly)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0036360"(sorocarp stalk morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045178"(basal part of cell)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051639"(actin filament network formation)|go:"GO:1905345"(protein localization to cleavage furrow)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015383(Cortexillin I, coiled coil)|interpro:IPR036872|rcsb pdb:1D7M|rcsb pdb:4J4A|refseq:XP_636175.1 - - - figure legend:Fig 3C taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") - 2008/09/12 2014/10/16 rogid:kBmhXb5GJdKRREo3zRPPLA/xf2c44689 rogid:nR4dqp8ukLUBbsx2YGw59RErL3k44689 intact-crc:853A9140D9A4FC42|rigid:pkpW9SrbMO7JlnDpVyC+WD7PgPo false green fluorescent protein tag:n-n|mutation disrupting interaction:12-12 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P34144 uniprotkb:Q54K32 intact:EBI-1808643|uniprotkb:Q54YK6|uniprotkb:Q9GPU0|ensemblprotists:EAL68107 intact:EBI-1808670|uniprotkb:O15815|uniprotkb:P90531|intact:EBI-1997884|ensemblprotists:EAL63601 psi-mi:rac1a_dicdi(display_long)|uniprotkb:rac1A(gene name)|psi-mi:rac1A(display_short)|uniprotkb:DDB_G0277869(orf name) psi-mi:rgaa_dicdi(display_long)|uniprotkb:rgaA(gene name)|psi-mi:rgaA(display_short)|uniprotkb:DDB_G0287585(orf name)|uniprotkb:DG1029(gene name synonym)|uniprotkb:rasGAP1(gene name synonym)|uniprotkb:Developmental gene 1029 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Faix et al. (2001) pubmed:11447112 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1811047 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dictybase:DDB_G0277869|ensemblprotists:DDB_G0277869(gene)|ensemblprotists:EAL68107(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005811"(lipid droplet)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1902412"(regulation of mitotic cytokinesis)|go:"GO:1904269"(cell leading edge cell cortex)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DDI-193648|reactome:R-DDI-2029482|reactome:R-DDI-389359|reactome:R-DDI-3928662|reactome:R-DDI-445144|reactome:R-DDI-5626467|reactome:R-DDI-5627123|reactome:R-DDI-5663213|reactome:R-DDI-5668599|reactome:R-DDI-5687128|reactome:R-DDI-6798695|reactome:R-DDI-9013149|reactome:R-DDI-9013404|reactome:R-DDI-9013407|reactome:R-DDI-9013418|reactome:R-DDI-9013420|reactome:R-DDI-9013422|reactome:R-DDI-9013424|reactome:R-DDI-9706019|reactome:R-DDI-983231|refseq:XP_642196.1 dictybase:DDB_G0287585|go:"GO:0007165"(signal transduction)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030587"(sorocarp development)|go:"GO:0031149"(sorocarp stalk cell differentiation)|go:"GO:0031154"(culmination involved in sorocarp development)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031255"(lateral part of motile cell)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036360"(sorocarp stalk morphogenesis)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045180"(basal cortex)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0140509"(epithelium-like organization)|go:"GO:1903665"(negative regulation of asexual reproduction)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-DDI-5626467|reactome:R-DDI-5674135|reactome:R-DDI-6798695|reactome:R-DDI-9013149|reactome:R-DDI-9013404|reactome:R-DDI-9013420|reactome:R-DDI-9013424|refseq:XP_637132.1|ensemblprotists:DDB_G0287585(gene)|ensemblprotists:EAL63601(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex) - - - figure legend:Fig 3C taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") - 2008/09/12 2014/10/16 rogid:kBmhXb5GJdKRREo3zRPPLA/xf2c44689 rogid:4XjyZq0wzx6CBoAiZ+82m3JQrWg44689 intact-crc:853A9140D9A4FC42|rigid:pkpW9SrbMO7JlnDpVyC+WD7PgPo false green fluorescent protein tag:n-n|mutation disrupting interaction:12-12 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P34144 uniprotkb:Q550R2 intact:EBI-1808643|uniprotkb:Q54YK6|uniprotkb:Q9GPU0|ensemblprotists:EAL68107 intact:EBI-1811057|uniprotkb:O15814|uniprotkb:Q8MNG7|ensemblprotists:EAL68948 psi-mi:rac1a_dicdi(display_long)|uniprotkb:rac1A(gene name)|psi-mi:rac1A(display_short)|uniprotkb:DDB_G0277869(orf name) psi-mi:ctxb_dicdi(display_long)|uniprotkb:ctxB(gene name)|psi-mi:ctxB(display_short)|uniprotkb:Cortexillin II(gene name synonym)|uniprotkb:DDB_G0276893(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Faix et al. (2001) pubmed:11447112 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1811047 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dictybase:DDB_G0277869|ensemblprotists:DDB_G0277869(gene)|ensemblprotists:EAL68107(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005811"(lipid droplet)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1902412"(regulation of mitotic cytokinesis)|go:"GO:1904269"(cell leading edge cell cortex)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DDI-193648|reactome:R-DDI-2029482|reactome:R-DDI-389359|reactome:R-DDI-3928662|reactome:R-DDI-445144|reactome:R-DDI-5626467|reactome:R-DDI-5627123|reactome:R-DDI-5663213|reactome:R-DDI-5668599|reactome:R-DDI-5687128|reactome:R-DDI-6798695|reactome:R-DDI-9013149|reactome:R-DDI-9013404|reactome:R-DDI-9013407|reactome:R-DDI-9013418|reactome:R-DDI-9013420|reactome:R-DDI-9013422|reactome:R-DDI-9013424|reactome:R-DDI-9706019|reactome:R-DDI-983231|refseq:XP_642196.1 dictybase:DDB_G0276893|ensemblprotists:DDB_G0276893(gene)|ensemblprotists:EAL68948(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030587"(sorocarp development)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031254"(cell trailing edge)|go:"GO:0032060"(bleb assembly)|go:"GO:0032154"(cleavage furrow)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015383(Cortexillin I, coiled coil)|interpro:IPR036872|reactome:R-DDI-6807878|refseq:XP_642870.1 - - - figure legend:Fig 3C taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") - 2008/09/12 2014/10/16 rogid:kBmhXb5GJdKRREo3zRPPLA/xf2c44689 rogid:n83KIrdrZXMDCdb/kIBUaoAdaNs44689 intact-crc:853A9140D9A4FC42|rigid:pkpW9SrbMO7JlnDpVyC+WD7PgPo false green fluorescent protein tag:n-n|mutation disrupting interaction:12-12 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q550R2 uniprotkb:Q54HG2 intact:EBI-1811057|uniprotkb:O15814|uniprotkb:Q8MNG7|ensemblprotists:EAL68948 intact:EBI-1810875|uniprotkb:O15813|ensemblprotists:EAL62673 psi-mi:ctxb_dicdi(display_long)|uniprotkb:ctxB(gene name)|psi-mi:ctxB(display_short)|uniprotkb:Cortexillin II(gene name synonym)|uniprotkb:DDB_G0276893(orf name) psi-mi:ctxa_dicdi(display_long)|uniprotkb:ctxA(gene name)|psi-mi:ctxA(display_short)|uniprotkb:Cortexillin I(gene name synonym)|uniprotkb:DDB_G0289483(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Faix et al. (2001) pubmed:11447112 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1811207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dictybase:DDB_G0276893|ensemblprotists:DDB_G0276893(gene)|ensemblprotists:EAL68948(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030587"(sorocarp development)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031254"(cell trailing edge)|go:"GO:0032060"(bleb assembly)|go:"GO:0032154"(cleavage furrow)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015383(Cortexillin I, coiled coil)|interpro:IPR036872|reactome:R-DDI-6807878|refseq:XP_642870.1 dictybase:DDB_G0289483|dip:DIP-52435N|ensemblprotists:DDB_G0289483(gene)|ensemblprotists:EAL62673(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0009617"(response to bacterium)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031255"(lateral part of motile cell)|go:"GO:0031982"(vesicle)|go:"GO:0032060"(bleb assembly)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0036360"(sorocarp stalk morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045178"(basal part of cell)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051639"(actin filament network formation)|go:"GO:1905345"(protein localization to cleavage furrow)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015383(Cortexillin I, coiled coil)|interpro:IPR036872|rcsb pdb:1D7M|rcsb pdb:4J4A|refseq:XP_636175.1 - - - figure legend:Fig 5D taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") - 2008/09/12 2014/10/16 rogid:n83KIrdrZXMDCdb/kIBUaoAdaNs44689 rogid:nR4dqp8ukLUBbsx2YGw59RErL3k44689 intact-crc:3724A42BADABB152|rigid:jVc2m9Pxv/uiDzN1a7gJ4KjETQA false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot)