#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P32562	uniprotkb:P32944	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	intact:EBI-18607|ensemblfungi:YJL187C|uniprotkb:D6VW03	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:swe1_yeast(display_long)|uniprotkb:SWE1(gene name)|psi-mi:SWE1(display_short)|uniprotkb:YJL187C(locus name)|uniprotkb:J0406(orf name)|uniprotkb:Wee1 homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bartholomew et al. (2001)	pubmed:11438652|imex:IM-18923	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2124274|imex:IM-18923-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-156711|go:"GO:0044879"(mitotic morphogenesis checkpoint signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090154"(positive regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblfungi:YJL187C(gene)|ensemblfungi:YJL187C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010697"(negative regulation of mitotic spindle pole body separation)|go:"GO:0040020"(regulation of meiotic nuclear division)|refseq:NP_012348.1|sgd:S000003723|dip:DIP-2410N|mint:P32944	-	crc64:B5A25F1BBBEAA3DC	crc64:F49FE73937958A02	figure legend:No fig.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/12/04	2014/10/16	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	rogid:rQHcS07YwbQQy+H5vuE8qkMRcvs559292	intact-crc:3762AFD8D6C95C09|rigid:+rLbpDJFJZMh19MMYWTgfBB10N8	false	-	binding-associated region:173-819	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32944	uniprotkb:P32562	intact:EBI-18607|ensemblfungi:YJL187C|uniprotkb:D6VW03	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:swe1_yeast(display_long)|uniprotkb:SWE1(gene name)|psi-mi:SWE1(display_short)|uniprotkb:YJL187C(locus name)|uniprotkb:J0406(orf name)|uniprotkb:Wee1 homolog(gene name synonym)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:0018"(two hybrid)	Bartholomew et al. (2001)	pubmed:11438652|imex:IM-18923	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2124280|imex:IM-18923-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-156711|go:"GO:0044879"(mitotic morphogenesis checkpoint signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090154"(positive regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblfungi:YJL187C(gene)|ensemblfungi:YJL187C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010697"(negative regulation of mitotic spindle pole body separation)|go:"GO:0040020"(regulation of meiotic nuclear division)|refseq:NP_012348.1|sgd:S000003723|dip:DIP-2410N|mint:P32944	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	-	crc64:F49FE73937958A02	crc64:B5A25F1BBBEAA3DC	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/12/04	2014/10/16	rogid:rQHcS07YwbQQy+H5vuE8qkMRcvs559292	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	intact-crc:D837CE3E0EF0CCF5|rigid:+rLbpDJFJZMh19MMYWTgfBB10N8	false	binding-associated region:173-819	binding-associated region:340-705	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32562	uniprotkb:P32944	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	intact:EBI-18607|ensemblfungi:YJL187C|uniprotkb:D6VW03	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:swe1_yeast(display_long)|uniprotkb:SWE1(gene name)|psi-mi:SWE1(display_short)|uniprotkb:YJL187C(locus name)|uniprotkb:J0406(orf name)|uniprotkb:Wee1 homolog(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Bartholomew et al. (2001)	pubmed:11438652|imex:IM-18923	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2124288|imex:IM-18923-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-156711|go:"GO:0044879"(mitotic morphogenesis checkpoint signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090154"(positive regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblfungi:YJL187C(gene)|ensemblfungi:YJL187C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010697"(negative regulation of mitotic spindle pole body separation)|go:"GO:0040020"(regulation of meiotic nuclear division)|refseq:NP_012348.1|sgd:S000003723|dip:DIP-2410N|mint:P32944	-	crc64:B5A25F1BBBEAA3DC	crc64:F49FE73937958A02	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/12/04	2014/10/16	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	rogid:rQHcS07YwbQQy+H5vuE8qkMRcvs559292	intact-crc:709A58150D99AFDD|rigid:+rLbpDJFJZMh19MMYWTgfBB10N8	false	protein a tag:n-n	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)