#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P12868 uniprotkb:P27801 intact:EBI-6450|uniprotkb:D6W057|ensemblfungi:YMR231W intact:EBI-13130|uniprotkb:D6VYE3|ensemblfungi:YLR148W psi-mi:pep5_yeast(display_long)|uniprotkb:PEP5(gene name)|psi-mi:PEP5(display_short)|uniprotkb:END1(gene name synonym)|uniprotkb:Histone E3 ligase PEP5(gene name synonym)|uniprotkb:Vacuolar biogenesis protein END1(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 11(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 1(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 11(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 5(gene name synonym)|uniprotkb:VAM1(gene name synonym)|uniprotkb:VPL9(gene name synonym)|uniprotkb:VPS11(gene name synonym)|uniprotkb:VPT11(gene name synonym)|uniprotkb:YM9959.13(orf name)|uniprotkb:YMR231W(locus name)|uniprotkb:RING-type E3 ubiquitin transferase PEP5(gene name synonym) psi-mi:pep3_yeast(display_long)|uniprotkb:VAM8(gene name synonym)|uniprotkb:VPS18(gene name synonym)|uniprotkb:VPT18(gene name synonym)|uniprotkb:L9634.2(orf name)|uniprotkb:YLR148W(locus name)|uniprotkb:PEP3(gene name)|psi-mi:PEP3(display_short)|uniprotkb:Vacuolar protein sorting-associated protein 18(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 8(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 18(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Srivastava et al. (2000) pubmed:10978279|imex:IM-19565 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1794778|imex:IM-19565-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013958.1|sgd:S000004844|mint:P12868|dip:DIP-4409N|ensemblfungi:YMR231W(gene)|ensemblfungi:YMR231W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0036205"(histone catabolic process)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0099022"(vesicle tethering)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322 refseq:NP_013249.1|sgd:S000004138|mint:P27801|dip:DIP-5912N|ensemblfungi:YLR148W(gene)|ensemblfungi:YLR148W_mRNA(transcript)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0099022"(vesicle tethering)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange)|rcsb pdb:4UUY - crc64:E5216AD3C285CF34 crc64:37AE3C34AE0470B8 figure legend:Fig. 8A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/17 2014/10/16 rogid:xEGHUcsIIYJCmMvkniYtRd7XE+s559292 rogid:AVu+SV1ZyurPbskFNoxIyGlo0n0559292 intact-crc:A154925FC311CB2B|rigid:E4mN7kMelqUxMmquExQBzeHZAy0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12868 uniprotkb:P12868 intact:EBI-6450|uniprotkb:D6W057|ensemblfungi:YMR231W intact:EBI-6450|uniprotkb:D6W057|ensemblfungi:YMR231W psi-mi:pep5_yeast(display_long)|uniprotkb:PEP5(gene name)|psi-mi:PEP5(display_short)|uniprotkb:END1(gene name synonym)|uniprotkb:Histone E3 ligase PEP5(gene name synonym)|uniprotkb:Vacuolar biogenesis protein END1(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 11(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 1(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 11(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 5(gene name synonym)|uniprotkb:VAM1(gene name synonym)|uniprotkb:VPL9(gene name synonym)|uniprotkb:VPS11(gene name synonym)|uniprotkb:VPT11(gene name synonym)|uniprotkb:YM9959.13(orf name)|uniprotkb:YMR231W(locus name)|uniprotkb:RING-type E3 ubiquitin transferase PEP5(gene name synonym) psi-mi:pep5_yeast(display_long)|uniprotkb:PEP5(gene name)|psi-mi:PEP5(display_short)|uniprotkb:END1(gene name synonym)|uniprotkb:Histone E3 ligase PEP5(gene name synonym)|uniprotkb:Vacuolar biogenesis protein END1(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 11(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 1(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 11(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 5(gene name synonym)|uniprotkb:VAM1(gene name synonym)|uniprotkb:VPL9(gene name synonym)|uniprotkb:VPS11(gene name synonym)|uniprotkb:VPT11(gene name synonym)|uniprotkb:YM9959.13(orf name)|uniprotkb:YMR231W(locus name)|uniprotkb:RING-type E3 ubiquitin transferase PEP5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Srivastava et al. (2000) pubmed:10978279|imex:IM-19565 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1794782|imex:IM-19565-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013958.1|sgd:S000004844|mint:P12868|dip:DIP-4409N|ensemblfungi:YMR231W(gene)|ensemblfungi:YMR231W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0036205"(histone catabolic process)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0099022"(vesicle tethering)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322 refseq:NP_013958.1|sgd:S000004844|mint:P12868|dip:DIP-4409N|ensemblfungi:YMR231W(gene)|ensemblfungi:YMR231W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0036205"(histone catabolic process)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0099022"(vesicle tethering)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322 - crc64:E5216AD3C285CF34 crc64:E5216AD3C285CF34 figure legend:Fig. 8A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/17 2014/10/16 rogid:xEGHUcsIIYJCmMvkniYtRd7XE+s559292 rogid:xEGHUcsIIYJCmMvkniYtRd7XE+s559292 intact-crc:F0A9EB9E9A9CFA60|rigid:ZtMpnXqK6nPkzcvVP+VCewejoYU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32609 uniprotkb:P12868 intact:EBI-20208|uniprotkb:Q99229|uniprotkb:D6VSV6|ensemblfungi:YDR323C intact:EBI-6450|uniprotkb:D6W057|ensemblfungi:YMR231W psi-mi:pep7_yeast(display_long)|uniprotkb:PEP7(gene name)|psi-mi:PEP7(display_short)|uniprotkb:VAC1(gene name synonym)|uniprotkb:Protein VAC1(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 19(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 19(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 7(gene name synonym)|uniprotkb:VPL21(gene name synonym)|uniprotkb:VPS19(gene name synonym)|uniprotkb:VPT19(gene name synonym)|uniprotkb:YDR323C(locus name) psi-mi:pep5_yeast(display_long)|uniprotkb:PEP5(gene name)|psi-mi:PEP5(display_short)|uniprotkb:END1(gene name synonym)|uniprotkb:Histone E3 ligase PEP5(gene name synonym)|uniprotkb:Vacuolar biogenesis protein END1(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 11(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 1(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 11(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 5(gene name synonym)|uniprotkb:VAM1(gene name synonym)|uniprotkb:VPL9(gene name synonym)|uniprotkb:VPS11(gene name synonym)|uniprotkb:VPT11(gene name synonym)|uniprotkb:YM9959.13(orf name)|uniprotkb:YMR231W(locus name)|uniprotkb:RING-type E3 ubiquitin transferase PEP5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Srivastava et al. (2000) pubmed:10978279|imex:IM-19565 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1794789|imex:IM-19565-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002731|reactome:R-SCE-983231|ensemblfungi:YDR323C(gene)|ensemblfungi:YDR323C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|refseq:NP_010610.3|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0010009"(cytoplasmic side of endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR021565|interpro:IPR036531|dip:DIP-5240N refseq:NP_013958.1|sgd:S000004844|mint:P12868|dip:DIP-4409N|ensemblfungi:YMR231W(gene)|ensemblfungi:YMR231W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0036205"(histone catabolic process)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0099022"(vesicle tethering)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322 - crc64:53C304F1ADA5B7A1 crc64:E5216AD3C285CF34 figure legend:Fig. 8A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/17 2014/10/16 rogid:3DMgFRejqoW4RFm8z1mEJI1nMpg559292 rogid:xEGHUcsIIYJCmMvkniYtRd7XE+s559292 intact-crc:321314451974303E|rigid:ojlNQhCAWF2VG3nz2j4ncCWhVWs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12904 uniprotkb:P06782 intact:EBI-17537|ensemblfungi:YGL115W|uniprotkb:D6VU32 intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W psi-mi:aakg_yeast(display_long)|uniprotkb:SNF4(gene name)|psi-mi:SNF4(display_short)|uniprotkb:CAT3(gene name synonym)|uniprotkb:Regulatory protein CAT3(gene name synonym)|uniprotkb:SCI1(gene name synonym)|uniprotkb:Sucrose non-fermenting protein 4(gene name synonym)|uniprotkb:YGL115W(locus name) psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name) psi-mi:"MI:0018"(two hybrid) Srivastava et al. (2000) pubmed:10978279|imex:IM-19565 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1794795|imex:IM-19565-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|ensemblfungi:YGL115W(gene)|ensemblfungi:YGL115W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|refseq:NP_011400.1|sgd:S000003083|go:"GO:0007031"(peroxisome organization)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|rcsb pdb:2NYC|rcsb pdb:2NYE|rcsb pdb:2QLV|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|dip:DIP-592N|mint:P12904 refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782 - crc64:51B387E346EE9561 crc64:F5C63565C986C4E3 figure legend:Fig. 8A & 8B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/17 2014/10/16 rogid:dYtx5LQZtt2QZX/VelN4akMH7KA559292 rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292 intact-crc:FD7F472A5CBC6810|rigid:4MHnCvJEe/pauqdj+JsPSZ8Bj+o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27801 uniprotkb:P27801 intact:EBI-13130|uniprotkb:D6VYE3|ensemblfungi:YLR148W intact:EBI-13130|uniprotkb:D6VYE3|ensemblfungi:YLR148W psi-mi:pep3_yeast(display_long)|uniprotkb:VAM8(gene name synonym)|uniprotkb:VPS18(gene name synonym)|uniprotkb:VPT18(gene name synonym)|uniprotkb:L9634.2(orf name)|uniprotkb:YLR148W(locus name)|uniprotkb:PEP3(gene name)|psi-mi:PEP3(display_short)|uniprotkb:Vacuolar protein sorting-associated protein 18(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 8(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 18(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 3(gene name synonym) psi-mi:pep3_yeast(display_long)|uniprotkb:VAM8(gene name synonym)|uniprotkb:VPS18(gene name synonym)|uniprotkb:VPT18(gene name synonym)|uniprotkb:L9634.2(orf name)|uniprotkb:YLR148W(locus name)|uniprotkb:PEP3(gene name)|psi-mi:PEP3(display_short)|uniprotkb:Vacuolar protein sorting-associated protein 18(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 8(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 18(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Srivastava et al. (2000) pubmed:10978279|imex:IM-19565 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1794805|imex:IM-19565-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013249.1|sgd:S000004138|mint:P27801|dip:DIP-5912N|ensemblfungi:YLR148W(gene)|ensemblfungi:YLR148W_mRNA(transcript)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0099022"(vesicle tethering)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange)|rcsb pdb:4UUY refseq:NP_013249.1|sgd:S000004138|mint:P27801|dip:DIP-5912N|ensemblfungi:YLR148W(gene)|ensemblfungi:YLR148W_mRNA(transcript)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0099022"(vesicle tethering)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange)|rcsb pdb:4UUY - crc64:37AE3C34AE0470B8 crc64:37AE3C34AE0470B8 figure legend:Fig. 8B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/17 2014/10/16 rogid:AVu+SV1ZyurPbskFNoxIyGlo0n0559292 rogid:AVu+SV1ZyurPbskFNoxIyGlo0n0559292 intact-crc:7EB60433F1EE4B07|rigid:zrn/U1oLlGVMaVnhe4lnoj6go6c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32609 uniprotkb:P27801 intact:EBI-20208|uniprotkb:Q99229|uniprotkb:D6VSV6|ensemblfungi:YDR323C intact:EBI-13130|uniprotkb:D6VYE3|ensemblfungi:YLR148W psi-mi:pep7_yeast(display_long)|uniprotkb:PEP7(gene name)|psi-mi:PEP7(display_short)|uniprotkb:VAC1(gene name synonym)|uniprotkb:Protein VAC1(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 19(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 19(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 7(gene name synonym)|uniprotkb:VPL21(gene name synonym)|uniprotkb:VPS19(gene name synonym)|uniprotkb:VPT19(gene name synonym)|uniprotkb:YDR323C(locus name) psi-mi:pep3_yeast(display_long)|uniprotkb:VAM8(gene name synonym)|uniprotkb:VPS18(gene name synonym)|uniprotkb:VPT18(gene name synonym)|uniprotkb:L9634.2(orf name)|uniprotkb:YLR148W(locus name)|uniprotkb:PEP3(gene name)|psi-mi:PEP3(display_short)|uniprotkb:Vacuolar protein sorting-associated protein 18(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 8(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 18(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Srivastava et al. (2000) pubmed:10978279|imex:IM-19565 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1794809|imex:IM-19565-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002731|reactome:R-SCE-983231|ensemblfungi:YDR323C(gene)|ensemblfungi:YDR323C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|refseq:NP_010610.3|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0010009"(cytoplasmic side of endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR021565|interpro:IPR036531|dip:DIP-5240N refseq:NP_013249.1|sgd:S000004138|mint:P27801|dip:DIP-5912N|ensemblfungi:YLR148W(gene)|ensemblfungi:YLR148W_mRNA(transcript)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0099022"(vesicle tethering)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange)|rcsb pdb:4UUY - crc64:53C304F1ADA5B7A1 crc64:37AE3C34AE0470B8 figure legend:Fig. 8B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/17 2014/10/16 rogid:3DMgFRejqoW4RFm8z1mEJI1nMpg559292 rogid:AVu+SV1ZyurPbskFNoxIyGlo0n0559292 intact-crc:83D7C2C185891695|rigid:mMvdZ/MtzRoiFK4dr3mp7nS5LbE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38932 uniprotkb:P32609 intact:EBI-20444|uniprotkb:D6VU50|ensemblfungi:YGL095C intact:EBI-20208|uniprotkb:Q99229|uniprotkb:D6VSV6|ensemblfungi:YDR323C psi-mi:vps45_yeast(display_long)|uniprotkb:VPS45(gene name)|psi-mi:VPS45(display_short)|uniprotkb:STT10(gene name synonym)|uniprotkb:VPL28(gene name synonym)|uniprotkb:YGL095C(locus name) psi-mi:pep7_yeast(display_long)|uniprotkb:PEP7(gene name)|psi-mi:PEP7(display_short)|uniprotkb:VAC1(gene name synonym)|uniprotkb:Protein VAC1(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 19(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 19(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 7(gene name synonym)|uniprotkb:VPL21(gene name synonym)|uniprotkb:VPS19(gene name synonym)|uniprotkb:VPT19(gene name synonym)|uniprotkb:YDR323C(locus name) psi-mi:"MI:0018"(two hybrid) Srivastava et al. (2000) pubmed:10978279|imex:IM-19565 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1794820|imex:IM-19565-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003063|refseq:NP_011420.3|ensemblfungi:YGL095C(gene)|ensemblfungi:YGL095C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007033"(vacuole organization)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0035543"(positive regulation of SNARE complex assembly)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|reactome:R-SCE-983231|dip:DIP-2693N|mint:P38932 sgd:S000002731|reactome:R-SCE-983231|ensemblfungi:YDR323C(gene)|ensemblfungi:YDR323C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|refseq:NP_010610.3|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0010009"(cytoplasmic side of endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR021565|interpro:IPR036531|dip:DIP-5240N - crc64:4AA50D568228228F crc64:53C304F1ADA5B7A1 figure legend:No figure.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/07/17 2014/10/16 rogid:HSNdSBz2AD5AS/nSUjPV02ym8HQ559292 rogid:3DMgFRejqoW4RFm8z1mEJI1nMpg559292 intact-crc:71014421B57E853C|rigid:p2XBRcaJ15Q6RU3nH9MiP+wYIbk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)