#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0A8T7 uniprotkb:P00579 intact:EBI-543604|uniprotkb:P00577|uniprotkb:P00578|uniprotkb:P78134|uniprotkb:Q2M8S4|ensemblbacteria:AAC76962|ensemblbacteria:BAE77332 intact:EBI-545104|uniprotkb:Q2M9D8|ensemblbacteria:AAC76103|ensemblbacteria:BAE77118 psi-mi:rpoc_ecoli(display_long)|uniprotkb:rpoC(gene name)|psi-mi:rpoC(display_short)|uniprotkb:tabB(gene name synonym)|uniprotkb:b3988(locus name)|uniprotkb:JW3951(locus name)|uniprotkb:Transcriptase subunit beta'(gene name synonym)|uniprotkb:RNA polymerase subunit beta'(gene name synonym) psi-mi:rpod_ecoli(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:alt(gene name synonym)|uniprotkb:b3067(locus name)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:JW3039(locus name) psi-mi:"MI:0047"(far western blotting) Arthur et al. (2000) pubmed:10764785|imex:IM-19581 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2116718|imex:IM-19581-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012754(DNA-directed RNA polymerase, subunit beta-prime)|interpro:IPR038120|interpro:IPR042102|rcsb pdb:2AUK|rcsb pdb:2LMC|rcsb pdb:3IYD|rcsb pdb:3LU0|rcsb pdb:4IQZ|rcsb pdb:4JK1|rcsb pdb:4JK2|rcsb pdb:4KMU|rcsb pdb:4KN4|rcsb pdb:4KN7|rcsb pdb:4MEX|rcsb pdb:4MEY|rcsb pdb:4XSX|rcsb pdb:4XSY|rcsb pdb:4XSZ|rcsb pdb:4YG2|rcsb pdb:4YLN|ensemblbacteria:AAC76962(transcript)|ensemblbacteria:b3988(gene)|ensemblbacteria:BAE77332(gene)|ensemblbacteria:BAE77332(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0046677"(response to antibiotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|refseq:NP_418415.1|rcsb pdb:4YLP|rcsb pdb:4ZH2|rcsb pdb:4ZH3|rcsb pdb:4ZH4|rcsb pdb:5BYH|rcsb pdb:5EZK|rcsb pdb:5IPL|rcsb pdb:5IPM|rcsb pdb:5IPN|rcsb pdb:5MS0|rcsb pdb:5MY1|rcsb pdb:5NSR|rcsb pdb:5NSS|rcsb pdb:5NWT|rcsb pdb:5UAC|rcsb pdb:5UAG|rcsb pdb:5UAH|rcsb pdb:5UAJ|rcsb pdb:5UAL|rcsb pdb:5UAQ|rcsb pdb:5VSW|rcsb pdb:5VT0|rcsb pdb:5W1S|rcsb pdb:5W1T|rcsb pdb:6ALF|rcsb pdb:6ALG|rcsb pdb:6ALH|rcsb pdb:6ASX|rcsb pdb:6BJS|rcsb pdb:6BYU|rcsb pdb:6C6S|rcsb pdb:6C6T|rcsb pdb:6C6U|rcsb pdb:6C9Y|rcsb pdb:6CA0|rcsb pdb:6CUX|rcsb pdb:6FLP|rcsb pdb:6FLQ|rcsb pdb:6GFW|rcsb pdb:6GH5|rcsb pdb:6GH6|rcsb pdb:6JBQ|rcsb pdb:6JNX|rcsb pdb:6K4Y|rcsb pdb:6KJ6|rcsb pdb:6LDI|rcsb pdb:6N4C|rcsb pdb:6N57|rcsb pdb:6N58|rcsb pdb:6N60|rcsb pdb:6N61|rcsb pdb:6OMF|rcsb pdb:6P18|rcsb pdb:6P19|rcsb pdb:6P1K|rcsb pdb:6PSQ|rcsb pdb:6PSR|rcsb pdb:6PSS|rcsb pdb:6PST|rcsb pdb:6PSU|rcsb pdb:6PSV|rcsb pdb:6PSW|rcsb pdb:6R9B|rcsb pdb:6R9G|rcsb pdb:6RH3|rcsb pdb:6RI7|rcsb pdb:6RI9|rcsb pdb:6RIN|rcsb pdb:6RIP|rcsb pdb:6TQN|rcsb pdb:6TQO|rcsb pdb:6UTV|rcsb pdb:6UTW|rcsb pdb:6UTX|rcsb pdb:6UTY|rcsb pdb:6UTZ|rcsb pdb:6UU0|rcsb pdb:6UU1|rcsb pdb:6UU2|rcsb pdb:6UU3|rcsb pdb:6UU4|rcsb pdb:6UU5|rcsb pdb:6UU6|rcsb pdb:6UU7|rcsb pdb:6UU8|rcsb pdb:6UU9|rcsb pdb:6UUA|rcsb pdb:6UUB|rcsb pdb:6UUC|rcsb pdb:6VJS|rcsb pdb:6WMU|rcsb pdb:6XAS|rcsb pdb:6XAV|rcsb pdb:7C17|rcsb pdb:7C97|rcsb pdb:7CHW|rcsb pdb:7KHB|rcsb pdb:7KHC|rcsb pdb:7KHE|rcsb pdb:7KHI|refseq:WP_000653944.1|dip:DIP-35803N|rcsb pdb:4YLO refseq:NP_417539.1|refseq:WP_000437376.1|ensemblbacteria:AAC76103(transcript)|ensemblbacteria:b3067(gene)|ensemblbacteria:BAE77118(gene)|ensemblbacteria:BAE77118(transcript)|go:"GO:0001123"|go:"GO:0003677"(DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016987"(sigma factor activity)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR028630|interpro:IPR036388|interpro:IPR042189|rcsb pdb:1SIG|rcsb pdb:1TLH|rcsb pdb:2P7V|rcsb pdb:3IYD|rcsb pdb:3T72|rcsb pdb:4JK1|rcsb pdb:4JK2|rcsb pdb:4JKR|rcsb pdb:4KMU|rcsb pdb:4KN4|rcsb pdb:4KN7|rcsb pdb:4LJZ|rcsb pdb:4LK0|rcsb pdb:4LK1|rcsb pdb:4LLG|rcsb pdb:4MEX|rcsb pdb:4MEY|rcsb pdb:4XSX|rcsb pdb:4XSY|rcsb pdb:4XSZ|rcsb pdb:4YFK|rcsb pdb:4YFN|rcsb pdb:4YFX|rcsb pdb:4YG2|rcsb pdb:4YLN|rcsb pdb:4YLO|rcsb pdb:4YLP|rcsb pdb:4ZH2|rcsb pdb:4ZH3|rcsb pdb:4ZH4|rcsb pdb:5UAC|rcsb pdb:5UAG|rcsb pdb:5UAH|rcsb pdb:5UAJ|rcsb pdb:5UAL|rcsb pdb:5UAQ|rcsb pdb:5VSW|rcsb pdb:5VT0|rcsb pdb:5W1S|rcsb pdb:5W1T|rcsb pdb:6B6H|rcsb pdb:6BYU|rcsb pdb:6C9Y|rcsb pdb:6CA0|rcsb pdb:6CUX|rcsb pdb:6JNX|rcsb pdb:6K4Y|rcsb pdb:6LDI|rcsb pdb:6N4C|rcsb pdb:6N57|rcsb pdb:6N58|rcsb pdb:6OUL|rcsb pdb:6P18|rcsb pdb:6P1K|rcsb pdb:6PB4|rcsb pdb:6PB5|rcsb pdb:6PB6|rcsb pdb:6PSQ|rcsb pdb:6PSR|rcsb pdb:6PSS|rcsb pdb:6PST|rcsb pdb:6PSU|rcsb pdb:6PSV|rcsb pdb:6PSW|rcsb pdb:6VJS|rcsb pdb:6XH7|rcsb pdb:6XH8|rcsb pdb:6XL5|rcsb pdb:6XL9|rcsb pdb:6XLJ|rcsb pdb:6XLL|rcsb pdb:6XLM|rcsb pdb:7C17|rcsb pdb:7C97|rcsb pdb:7CHW|rcsb pdb:7KHB|rcsb pdb:7KHC|rcsb pdb:7KHE|rcsb pdb:7KHI|dip:DIP-10773N - - - figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/11/20 2014/10/16 rogid:uZC9aRrl+QIT7zZtcO7WPVedhnA83333 rogid:jwUTAy6Qbz6rbF+rdM60BZQcmKM83333 intact-crc:9A6AFD73DB940406|rigid:v3/lNZMcNfyjWBPScmYfjNwyjgI false mutation decreasing interaction:293-293|sufficient binding region:1-319|mutation decreasing interaction:275-275|mutation decreasing interaction:295-295|mutation decreasing interaction:297-297|mutation decreasing interaction:302-302|mutation increasing interaction:300-300|mutation increasing interaction:309-309 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0A8T7 uniprotkb:P0A7Z4 intact:EBI-543604|uniprotkb:P00577|uniprotkb:P00578|uniprotkb:P78134|uniprotkb:Q2M8S4|ensemblbacteria:AAC76962|ensemblbacteria:BAE77332 intact:EBI-544985|uniprotkb:P00574|uniprotkb:Q2M6W0|ensemblbacteria:AAC76320|ensemblbacteria:BAE77996 psi-mi:rpoc_ecoli(display_long)|uniprotkb:rpoC(gene name)|psi-mi:rpoC(display_short)|uniprotkb:tabB(gene name synonym)|uniprotkb:b3988(locus name)|uniprotkb:JW3951(locus name)|uniprotkb:Transcriptase subunit beta'(gene name synonym)|uniprotkb:RNA polymerase subunit beta'(gene name synonym) psi-mi:rpoa_ecoli(display_long)|uniprotkb:rpoA(gene name)|psi-mi:rpoA(display_short)|uniprotkb:pez(gene name synonym)|uniprotkb:phs(gene name synonym)|uniprotkb:sez(gene name synonym)|uniprotkb:b3295(locus name)|uniprotkb:Transcriptase subunit alpha(gene name synonym)|uniprotkb:RNA polymerase subunit alpha(gene name synonym)|uniprotkb:JW3257(locus name) psi-mi:"MI:0096"(pull down) Arthur et al. (2000) pubmed:10764785|imex:IM-19581 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2116750|imex:IM-19581-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012754(DNA-directed RNA polymerase, subunit beta-prime)|interpro:IPR038120|interpro:IPR042102|rcsb pdb:2AUK|rcsb pdb:2LMC|rcsb pdb:3IYD|rcsb pdb:3LU0|rcsb pdb:4IQZ|rcsb pdb:4JK1|rcsb pdb:4JK2|rcsb pdb:4KMU|rcsb pdb:4KN4|rcsb pdb:4KN7|rcsb pdb:4MEX|rcsb pdb:4MEY|rcsb pdb:4XSX|rcsb pdb:4XSY|rcsb pdb:4XSZ|rcsb pdb:4YG2|rcsb pdb:4YLN|ensemblbacteria:AAC76962(transcript)|ensemblbacteria:b3988(gene)|ensemblbacteria:BAE77332(gene)|ensemblbacteria:BAE77332(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0046677"(response to antibiotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|refseq:NP_418415.1|rcsb pdb:4YLP|rcsb pdb:4ZH2|rcsb pdb:4ZH3|rcsb pdb:4ZH4|rcsb pdb:5BYH|rcsb pdb:5EZK|rcsb pdb:5IPL|rcsb pdb:5IPM|rcsb pdb:5IPN|rcsb pdb:5MS0|rcsb pdb:5MY1|rcsb pdb:5NSR|rcsb pdb:5NSS|rcsb pdb:5NWT|rcsb pdb:5UAC|rcsb pdb:5UAG|rcsb pdb:5UAH|rcsb pdb:5UAJ|rcsb pdb:5UAL|rcsb pdb:5UAQ|rcsb pdb:5VSW|rcsb pdb:5VT0|rcsb pdb:5W1S|rcsb pdb:5W1T|rcsb pdb:6ALF|rcsb pdb:6ALG|rcsb pdb:6ALH|rcsb pdb:6ASX|rcsb pdb:6BJS|rcsb pdb:6BYU|rcsb pdb:6C6S|rcsb pdb:6C6T|rcsb pdb:6C6U|rcsb pdb:6C9Y|rcsb pdb:6CA0|rcsb pdb:6CUX|rcsb pdb:6FLP|rcsb pdb:6FLQ|rcsb pdb:6GFW|rcsb pdb:6GH5|rcsb pdb:6GH6|rcsb pdb:6JBQ|rcsb pdb:6JNX|rcsb pdb:6K4Y|rcsb pdb:6KJ6|rcsb pdb:6LDI|rcsb pdb:6N4C|rcsb pdb:6N57|rcsb pdb:6N58|rcsb pdb:6N60|rcsb pdb:6N61|rcsb pdb:6OMF|rcsb pdb:6P18|rcsb pdb:6P19|rcsb pdb:6P1K|rcsb pdb:6PSQ|rcsb pdb:6PSR|rcsb pdb:6PSS|rcsb pdb:6PST|rcsb pdb:6PSU|rcsb pdb:6PSV|rcsb pdb:6PSW|rcsb pdb:6R9B|rcsb pdb:6R9G|rcsb pdb:6RH3|rcsb pdb:6RI7|rcsb pdb:6RI9|rcsb pdb:6RIN|rcsb pdb:6RIP|rcsb pdb:6TQN|rcsb pdb:6TQO|rcsb pdb:6UTV|rcsb pdb:6UTW|rcsb pdb:6UTX|rcsb pdb:6UTY|rcsb pdb:6UTZ|rcsb pdb:6UU0|rcsb pdb:6UU1|rcsb pdb:6UU2|rcsb pdb:6UU3|rcsb pdb:6UU4|rcsb pdb:6UU5|rcsb pdb:6UU6|rcsb pdb:6UU7|rcsb pdb:6UU8|rcsb pdb:6UU9|rcsb pdb:6UUA|rcsb pdb:6UUB|rcsb pdb:6UUC|rcsb pdb:6VJS|rcsb pdb:6WMU|rcsb pdb:6XAS|rcsb pdb:6XAV|rcsb pdb:7C17|rcsb pdb:7C97|rcsb pdb:7CHW|rcsb pdb:7KHB|rcsb pdb:7KHC|rcsb pdb:7KHE|rcsb pdb:7KHI|refseq:WP_000653944.1|dip:DIP-35803N|rcsb pdb:4YLO refseq:NP_417754.1|refseq:WP_001162094.1|ensemblbacteria:AAC76320(transcript)|ensemblbacteria:b3295(gene)|rcsb pdb:5NSS|ensemblbacteria:BAE77996(gene)|ensemblbacteria:BAE77996(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011260(RNA polymerase, alpha subunit, C-terminal)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR011773(DNA-directed RNA polymerase, alpha subunit)|interpro:IPR036603|interpro:IPR036643|rcsb pdb:1BDF|rcsb pdb:1COO|rcsb pdb:1LB2|rcsb pdb:1XS9|rcsb pdb:3IYD|rcsb pdb:3K4G|rcsb pdb:3LU0|rcsb pdb:3N4M|rcsb pdb:3N97|rcsb pdb:4JK1|rcsb pdb:4JK2|rcsb pdb:4KMU|rcsb pdb:4KN4|rcsb pdb:4KN7|rcsb pdb:4MEX|rcsb pdb:4MEY|rcsb pdb:4S20|rcsb pdb:4XSX|rcsb pdb:4XSY|rcsb pdb:4XSZ|rcsb pdb:4YG2|rcsb pdb:4YLN|rcsb pdb:4YLO|rcsb pdb:4YLP|rcsb pdb:4ZH2|rcsb pdb:4ZH3|rcsb pdb:4ZH4|rcsb pdb:5BYH|rcsb pdb:5CIZ|rcsb pdb:5EZK|rcsb pdb:5IPL|rcsb pdb:5IPM|rcsb pdb:5IPN|rcsb pdb:5MS0|rcsb pdb:5MY1|rcsb pdb:5NSR|rcsb pdb:6C9Y|rcsb pdb:6CA0|rcsb pdb:6CUX|rcsb pdb:6FLP|rcsb pdb:6FLQ|rcsb pdb:6GFW|rcsb pdb:6GH5|rcsb pdb:6GH6|rcsb pdb:6JBQ|rcsb pdb:6C6U|rcsb pdb:6JNX|rcsb pdb:6K4Y|rcsb pdb:6KJ6|rcsb pdb:6LDI|rcsb pdb:6N4C|rcsb pdb:6N57|rcsb pdb:6N58|rcsb pdb:6N60|rcsb pdb:6N61|rcsb pdb:6OMF|rcsb pdb:5NWT|rcsb pdb:5UAC|rcsb pdb:5UAG|rcsb pdb:5UAH|rcsb pdb:5UAJ|rcsb pdb:5UAL|rcsb pdb:5UAQ|rcsb pdb:5VSW|rcsb pdb:5VT0|rcsb pdb:5W1S|rcsb pdb:5W1T|rcsb pdb:6ALF|rcsb pdb:6ALG|rcsb pdb:6ALH|rcsb pdb:6ASX|rcsb pdb:6BJS|rcsb pdb:6BYU|rcsb pdb:6C6S|rcsb pdb:6C6T|rcsb pdb:6P18|rcsb pdb:6P19|rcsb pdb:6P1K|rcsb pdb:6PB4|rcsb pdb:6PB5|rcsb pdb:6PB6|rcsb pdb:6PMI|rcsb pdb:6PMJ|rcsb pdb:6PSQ|rcsb pdb:6PSR|rcsb pdb:6PSS|rcsb pdb:6PST|rcsb pdb:6PSU|rcsb pdb:6PSV|rcsb pdb:6PSW|rcsb pdb:6R9B|rcsb pdb:6R9G|rcsb pdb:6OUL|rcsb pdb:6RH3|rcsb pdb:6RI7|rcsb pdb:6RI9|rcsb pdb:6RIN|rcsb pdb:6TQN|rcsb pdb:6TQO|rcsb pdb:6UTW|rcsb pdb:6UTX|rcsb pdb:6UTY|rcsb pdb:6UU5|rcsb pdb:6UU6|rcsb pdb:6UU7|rcsb pdb:6UU8|rcsb pdb:6UUB|rcsb pdb:6VJS|rcsb pdb:6XAS|rcsb pdb:6XAV|rcsb pdb:6Z9P|rcsb pdb:6Z9Q|rcsb pdb:6Z9R|rcsb pdb:6Z9S|rcsb pdb:6Z9T|rcsb pdb:6ZTJ|rcsb pdb:6ZTL|rcsb pdb:6ZTM|rcsb pdb:6ZTN|rcsb pdb:6ZTO|rcsb pdb:6ZTP|rcsb pdb:6ZU1|rcsb pdb:6RIP|rcsb pdb:7ADB|rcsb pdb:7ADC|rcsb pdb:7ADD|rcsb pdb:7ADE|rcsb pdb:7C17|rcsb pdb:7C97|rcsb pdb:7CHW|rcsb pdb:7KHB|rcsb pdb:7KHC|rcsb pdb:7KHE|rcsb pdb:7KHI|mint:P0A7Z4|dip:DIP-35879N - - - figure legend:4|variable_condition:log phase|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/11/20 2014/10/16 rogid:uZC9aRrl+QIT7zZtcO7WPVedhnA83333 rogid:dpkf3DEbQiGwW9FbFES7hFqgs0E83333 intact-crc:9E9486DDAF9BDD8E|rigid:xuGNIud7E9hl/2oiJJ8b+e+rrWk false mutation decreasing interaction:293-293|mutation decreasing interaction:275-275|mutation decreasing interaction:295-295|mutation decreasing interaction:297-297|mutation decreasing interaction:302-302|his tag:?-?|mutation increasing interaction:300-300 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0A8T7 uniprotkb:P00579 intact:EBI-543604|uniprotkb:P00577|uniprotkb:P00578|uniprotkb:P78134|uniprotkb:Q2M8S4|ensemblbacteria:AAC76962|ensemblbacteria:BAE77332 intact:EBI-545104|uniprotkb:Q2M9D8|ensemblbacteria:AAC76103|ensemblbacteria:BAE77118 psi-mi:rpoc_ecoli(display_long)|uniprotkb:rpoC(gene name)|psi-mi:rpoC(display_short)|uniprotkb:tabB(gene name synonym)|uniprotkb:b3988(locus name)|uniprotkb:JW3951(locus name)|uniprotkb:Transcriptase subunit beta'(gene name synonym)|uniprotkb:RNA polymerase subunit beta'(gene name synonym) psi-mi:rpod_ecoli(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:alt(gene name synonym)|uniprotkb:b3067(locus name)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:JW3039(locus name) psi-mi:"MI:0096"(pull down) Arthur et al. (2000) pubmed:10764785|imex:IM-19581 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2116750|imex:IM-19581-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012754(DNA-directed RNA polymerase, subunit beta-prime)|interpro:IPR038120|interpro:IPR042102|rcsb pdb:2AUK|rcsb pdb:2LMC|rcsb pdb:3IYD|rcsb pdb:3LU0|rcsb pdb:4IQZ|rcsb pdb:4JK1|rcsb pdb:4JK2|rcsb pdb:4KMU|rcsb pdb:4KN4|rcsb pdb:4KN7|rcsb pdb:4MEX|rcsb pdb:4MEY|rcsb pdb:4XSX|rcsb pdb:4XSY|rcsb pdb:4XSZ|rcsb pdb:4YG2|rcsb pdb:4YLN|ensemblbacteria:AAC76962(transcript)|ensemblbacteria:b3988(gene)|ensemblbacteria:BAE77332(gene)|ensemblbacteria:BAE77332(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0046677"(response to antibiotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|refseq:NP_418415.1|rcsb pdb:4YLP|rcsb pdb:4ZH2|rcsb pdb:4ZH3|rcsb pdb:4ZH4|rcsb pdb:5BYH|rcsb pdb:5EZK|rcsb pdb:5IPL|rcsb pdb:5IPM|rcsb pdb:5IPN|rcsb pdb:5MS0|rcsb pdb:5MY1|rcsb pdb:5NSR|rcsb pdb:5NSS|rcsb pdb:5NWT|rcsb pdb:5UAC|rcsb pdb:5UAG|rcsb pdb:5UAH|rcsb pdb:5UAJ|rcsb pdb:5UAL|rcsb pdb:5UAQ|rcsb pdb:5VSW|rcsb pdb:5VT0|rcsb pdb:5W1S|rcsb pdb:5W1T|rcsb pdb:6ALF|rcsb pdb:6ALG|rcsb pdb:6ALH|rcsb pdb:6ASX|rcsb pdb:6BJS|rcsb pdb:6BYU|rcsb pdb:6C6S|rcsb pdb:6C6T|rcsb pdb:6C6U|rcsb pdb:6C9Y|rcsb pdb:6CA0|rcsb pdb:6CUX|rcsb pdb:6FLP|rcsb pdb:6FLQ|rcsb pdb:6GFW|rcsb pdb:6GH5|rcsb pdb:6GH6|rcsb pdb:6JBQ|rcsb pdb:6JNX|rcsb pdb:6K4Y|rcsb pdb:6KJ6|rcsb pdb:6LDI|rcsb pdb:6N4C|rcsb pdb:6N57|rcsb pdb:6N58|rcsb pdb:6N60|rcsb pdb:6N61|rcsb pdb:6OMF|rcsb pdb:6P18|rcsb pdb:6P19|rcsb pdb:6P1K|rcsb pdb:6PSQ|rcsb pdb:6PSR|rcsb pdb:6PSS|rcsb pdb:6PST|rcsb pdb:6PSU|rcsb pdb:6PSV|rcsb pdb:6PSW|rcsb pdb:6R9B|rcsb pdb:6R9G|rcsb pdb:6RH3|rcsb pdb:6RI7|rcsb pdb:6RI9|rcsb pdb:6RIN|rcsb pdb:6RIP|rcsb pdb:6TQN|rcsb pdb:6TQO|rcsb pdb:6UTV|rcsb pdb:6UTW|rcsb pdb:6UTX|rcsb pdb:6UTY|rcsb pdb:6UTZ|rcsb pdb:6UU0|rcsb pdb:6UU1|rcsb pdb:6UU2|rcsb pdb:6UU3|rcsb pdb:6UU4|rcsb pdb:6UU5|rcsb pdb:6UU6|rcsb pdb:6UU7|rcsb pdb:6UU8|rcsb pdb:6UU9|rcsb pdb:6UUA|rcsb pdb:6UUB|rcsb pdb:6UUC|rcsb pdb:6VJS|rcsb pdb:6WMU|rcsb pdb:6XAS|rcsb pdb:6XAV|rcsb pdb:7C17|rcsb pdb:7C97|rcsb pdb:7CHW|rcsb pdb:7KHB|rcsb pdb:7KHC|rcsb pdb:7KHE|rcsb pdb:7KHI|refseq:WP_000653944.1|dip:DIP-35803N|rcsb pdb:4YLO refseq:NP_417539.1|refseq:WP_000437376.1|ensemblbacteria:AAC76103(transcript)|ensemblbacteria:b3067(gene)|ensemblbacteria:BAE77118(gene)|ensemblbacteria:BAE77118(transcript)|go:"GO:0001123"|go:"GO:0003677"(DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016987"(sigma factor activity)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR028630|interpro:IPR036388|interpro:IPR042189|rcsb pdb:1SIG|rcsb pdb:1TLH|rcsb pdb:2P7V|rcsb pdb:3IYD|rcsb pdb:3T72|rcsb pdb:4JK1|rcsb pdb:4JK2|rcsb pdb:4JKR|rcsb pdb:4KMU|rcsb pdb:4KN4|rcsb pdb:4KN7|rcsb pdb:4LJZ|rcsb pdb:4LK0|rcsb pdb:4LK1|rcsb pdb:4LLG|rcsb pdb:4MEX|rcsb pdb:4MEY|rcsb pdb:4XSX|rcsb pdb:4XSY|rcsb pdb:4XSZ|rcsb pdb:4YFK|rcsb pdb:4YFN|rcsb pdb:4YFX|rcsb pdb:4YG2|rcsb pdb:4YLN|rcsb pdb:4YLO|rcsb pdb:4YLP|rcsb pdb:4ZH2|rcsb pdb:4ZH3|rcsb pdb:4ZH4|rcsb pdb:5UAC|rcsb pdb:5UAG|rcsb pdb:5UAH|rcsb pdb:5UAJ|rcsb pdb:5UAL|rcsb pdb:5UAQ|rcsb pdb:5VSW|rcsb pdb:5VT0|rcsb pdb:5W1S|rcsb pdb:5W1T|rcsb pdb:6B6H|rcsb pdb:6BYU|rcsb pdb:6C9Y|rcsb pdb:6CA0|rcsb pdb:6CUX|rcsb pdb:6JNX|rcsb pdb:6K4Y|rcsb pdb:6LDI|rcsb pdb:6N4C|rcsb pdb:6N57|rcsb pdb:6N58|rcsb pdb:6OUL|rcsb pdb:6P18|rcsb pdb:6P1K|rcsb pdb:6PB4|rcsb pdb:6PB5|rcsb pdb:6PB6|rcsb pdb:6PSQ|rcsb pdb:6PSR|rcsb pdb:6PSS|rcsb pdb:6PST|rcsb pdb:6PSU|rcsb pdb:6PSV|rcsb pdb:6PSW|rcsb pdb:6VJS|rcsb pdb:6XH7|rcsb pdb:6XH8|rcsb pdb:6XL5|rcsb pdb:6XL9|rcsb pdb:6XLJ|rcsb pdb:6XLL|rcsb pdb:6XLM|rcsb pdb:7C17|rcsb pdb:7C97|rcsb pdb:7CHW|rcsb pdb:7KHB|rcsb pdb:7KHC|rcsb pdb:7KHE|rcsb pdb:7KHI|dip:DIP-10773N - - - figure legend:4|variable_condition:log phase|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/11/20 2014/10/16 rogid:uZC9aRrl+QIT7zZtcO7WPVedhnA83333 rogid:jwUTAy6Qbz6rbF+rdM60BZQcmKM83333 intact-crc:9E9486DDAF9BDD8E|rigid:xuGNIud7E9hl/2oiJJ8b+e+rrWk false mutation decreasing interaction:293-293|mutation decreasing interaction:275-275|mutation decreasing interaction:295-295|mutation decreasing interaction:297-297|mutation decreasing interaction:302-302|his tag:?-?|mutation increasing interaction:300-300 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0A8T7 uniprotkb:P00579 intact:EBI-543604|uniprotkb:P00577|uniprotkb:P00578|uniprotkb:P78134|uniprotkb:Q2M8S4|ensemblbacteria:AAC76962|ensemblbacteria:BAE77332 intact:EBI-545104|uniprotkb:Q2M9D8|ensemblbacteria:AAC76103|ensemblbacteria:BAE77118 psi-mi:rpoc_ecoli(display_long)|uniprotkb:rpoC(gene name)|psi-mi:rpoC(display_short)|uniprotkb:tabB(gene name synonym)|uniprotkb:b3988(locus name)|uniprotkb:JW3951(locus name)|uniprotkb:Transcriptase subunit beta'(gene name synonym)|uniprotkb:RNA polymerase subunit beta'(gene name synonym) psi-mi:rpod_ecoli(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:alt(gene name synonym)|uniprotkb:b3067(locus name)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:JW3039(locus name) psi-mi:"MI:0096"(pull down) Arthur et al. (2000) pubmed:10764785|imex:IM-19581 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2123305|imex:IM-19581-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012754(DNA-directed RNA polymerase, subunit beta-prime)|interpro:IPR038120|interpro:IPR042102|rcsb pdb:2AUK|rcsb pdb:2LMC|rcsb pdb:3IYD|rcsb pdb:3LU0|rcsb pdb:4IQZ|rcsb pdb:4JK1|rcsb pdb:4JK2|rcsb pdb:4KMU|rcsb pdb:4KN4|rcsb pdb:4KN7|rcsb pdb:4MEX|rcsb pdb:4MEY|rcsb pdb:4XSX|rcsb pdb:4XSY|rcsb pdb:4XSZ|rcsb pdb:4YG2|rcsb pdb:4YLN|ensemblbacteria:AAC76962(transcript)|ensemblbacteria:b3988(gene)|ensemblbacteria:BAE77332(gene)|ensemblbacteria:BAE77332(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0046677"(response to antibiotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|refseq:NP_418415.1|rcsb pdb:4YLP|rcsb pdb:4ZH2|rcsb pdb:4ZH3|rcsb pdb:4ZH4|rcsb pdb:5BYH|rcsb pdb:5EZK|rcsb pdb:5IPL|rcsb pdb:5IPM|rcsb pdb:5IPN|rcsb pdb:5MS0|rcsb pdb:5MY1|rcsb pdb:5NSR|rcsb pdb:5NSS|rcsb pdb:5NWT|rcsb pdb:5UAC|rcsb pdb:5UAG|rcsb pdb:5UAH|rcsb pdb:5UAJ|rcsb pdb:5UAL|rcsb pdb:5UAQ|rcsb pdb:5VSW|rcsb pdb:5VT0|rcsb pdb:5W1S|rcsb pdb:5W1T|rcsb pdb:6ALF|rcsb pdb:6ALG|rcsb pdb:6ALH|rcsb pdb:6ASX|rcsb pdb:6BJS|rcsb pdb:6BYU|rcsb pdb:6C6S|rcsb pdb:6C6T|rcsb pdb:6C6U|rcsb pdb:6C9Y|rcsb pdb:6CA0|rcsb pdb:6CUX|rcsb pdb:6FLP|rcsb pdb:6FLQ|rcsb pdb:6GFW|rcsb pdb:6GH5|rcsb pdb:6GH6|rcsb pdb:6JBQ|rcsb pdb:6JNX|rcsb pdb:6K4Y|rcsb pdb:6KJ6|rcsb pdb:6LDI|rcsb pdb:6N4C|rcsb pdb:6N57|rcsb pdb:6N58|rcsb pdb:6N60|rcsb pdb:6N61|rcsb pdb:6OMF|rcsb pdb:6P18|rcsb pdb:6P19|rcsb pdb:6P1K|rcsb pdb:6PSQ|rcsb pdb:6PSR|rcsb pdb:6PSS|rcsb pdb:6PST|rcsb pdb:6PSU|rcsb pdb:6PSV|rcsb pdb:6PSW|rcsb pdb:6R9B|rcsb pdb:6R9G|rcsb pdb:6RH3|rcsb pdb:6RI7|rcsb pdb:6RI9|rcsb pdb:6RIN|rcsb pdb:6RIP|rcsb pdb:6TQN|rcsb pdb:6TQO|rcsb pdb:6UTV|rcsb pdb:6UTW|rcsb pdb:6UTX|rcsb pdb:6UTY|rcsb pdb:6UTZ|rcsb pdb:6UU0|rcsb pdb:6UU1|rcsb pdb:6UU2|rcsb pdb:6UU3|rcsb pdb:6UU4|rcsb pdb:6UU5|rcsb pdb:6UU6|rcsb pdb:6UU7|rcsb pdb:6UU8|rcsb pdb:6UU9|rcsb pdb:6UUA|rcsb pdb:6UUB|rcsb pdb:6UUC|rcsb pdb:6VJS|rcsb pdb:6WMU|rcsb pdb:6XAS|rcsb pdb:6XAV|rcsb pdb:7C17|rcsb pdb:7C97|rcsb pdb:7CHW|rcsb pdb:7KHB|rcsb pdb:7KHC|rcsb pdb:7KHE|rcsb pdb:7KHI|refseq:WP_000653944.1|dip:DIP-35803N|rcsb pdb:4YLO refseq:NP_417539.1|refseq:WP_000437376.1|ensemblbacteria:AAC76103(transcript)|ensemblbacteria:b3067(gene)|ensemblbacteria:BAE77118(gene)|ensemblbacteria:BAE77118(transcript)|go:"GO:0001123"|go:"GO:0003677"(DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016987"(sigma factor activity)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR028630|interpro:IPR036388|interpro:IPR042189|rcsb pdb:1SIG|rcsb pdb:1TLH|rcsb pdb:2P7V|rcsb pdb:3IYD|rcsb pdb:3T72|rcsb pdb:4JK1|rcsb pdb:4JK2|rcsb pdb:4JKR|rcsb pdb:4KMU|rcsb pdb:4KN4|rcsb pdb:4KN7|rcsb pdb:4LJZ|rcsb pdb:4LK0|rcsb pdb:4LK1|rcsb pdb:4LLG|rcsb pdb:4MEX|rcsb pdb:4MEY|rcsb pdb:4XSX|rcsb pdb:4XSY|rcsb pdb:4XSZ|rcsb pdb:4YFK|rcsb pdb:4YFN|rcsb pdb:4YFX|rcsb pdb:4YG2|rcsb pdb:4YLN|rcsb pdb:4YLO|rcsb pdb:4YLP|rcsb pdb:4ZH2|rcsb pdb:4ZH3|rcsb pdb:4ZH4|rcsb pdb:5UAC|rcsb pdb:5UAG|rcsb pdb:5UAH|rcsb pdb:5UAJ|rcsb pdb:5UAL|rcsb pdb:5UAQ|rcsb pdb:5VSW|rcsb pdb:5VT0|rcsb pdb:5W1S|rcsb pdb:5W1T|rcsb pdb:6B6H|rcsb pdb:6BYU|rcsb pdb:6C9Y|rcsb pdb:6CA0|rcsb pdb:6CUX|rcsb pdb:6JNX|rcsb pdb:6K4Y|rcsb pdb:6LDI|rcsb pdb:6N4C|rcsb pdb:6N57|rcsb pdb:6N58|rcsb pdb:6OUL|rcsb pdb:6P18|rcsb pdb:6P1K|rcsb pdb:6PB4|rcsb pdb:6PB5|rcsb pdb:6PB6|rcsb pdb:6PSQ|rcsb pdb:6PSR|rcsb pdb:6PSS|rcsb pdb:6PST|rcsb pdb:6PSU|rcsb pdb:6PSV|rcsb pdb:6PSW|rcsb pdb:6VJS|rcsb pdb:6XH7|rcsb pdb:6XH8|rcsb pdb:6XL5|rcsb pdb:6XL9|rcsb pdb:6XLJ|rcsb pdb:6XLL|rcsb pdb:6XLM|rcsb pdb:7C17|rcsb pdb:7C97|rcsb pdb:7CHW|rcsb pdb:7KHB|rcsb pdb:7KHC|rcsb pdb:7KHE|rcsb pdb:7KHI|dip:DIP-10773N - - - figure legend:4|variable_condition:stationary phase|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/11/20 2014/10/16 rogid:uZC9aRrl+QIT7zZtcO7WPVedhnA83333 rogid:jwUTAy6Qbz6rbF+rdM60BZQcmKM83333 intact-crc:20974055F1235303|rigid:xuGNIud7E9hl/2oiJJ8b+e+rrWk false mutation decreasing interaction:293-293|mutation decreasing interaction:275-275|mutation decreasing interaction:295-295|mutation decreasing interaction:302-302|his tag:?-?|mutation increasing interaction:300-300 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0A8T7 uniprotkb:P0A7Z4 intact:EBI-543604|uniprotkb:P00577|uniprotkb:P00578|uniprotkb:P78134|uniprotkb:Q2M8S4|ensemblbacteria:AAC76962|ensemblbacteria:BAE77332 intact:EBI-544985|uniprotkb:P00574|uniprotkb:Q2M6W0|ensemblbacteria:AAC76320|ensemblbacteria:BAE77996 psi-mi:rpoc_ecoli(display_long)|uniprotkb:rpoC(gene name)|psi-mi:rpoC(display_short)|uniprotkb:tabB(gene name synonym)|uniprotkb:b3988(locus name)|uniprotkb:JW3951(locus name)|uniprotkb:Transcriptase subunit beta'(gene name synonym)|uniprotkb:RNA polymerase subunit beta'(gene name synonym) psi-mi:rpoa_ecoli(display_long)|uniprotkb:rpoA(gene name)|psi-mi:rpoA(display_short)|uniprotkb:pez(gene name synonym)|uniprotkb:phs(gene name synonym)|uniprotkb:sez(gene name synonym)|uniprotkb:b3295(locus name)|uniprotkb:Transcriptase subunit alpha(gene name synonym)|uniprotkb:RNA polymerase subunit alpha(gene name synonym)|uniprotkb:JW3257(locus name) psi-mi:"MI:0096"(pull down) Arthur et al. (2000) pubmed:10764785|imex:IM-19581 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2123305|imex:IM-19581-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012754(DNA-directed RNA polymerase, subunit beta-prime)|interpro:IPR038120|interpro:IPR042102|rcsb pdb:2AUK|rcsb pdb:2LMC|rcsb pdb:3IYD|rcsb pdb:3LU0|rcsb pdb:4IQZ|rcsb pdb:4JK1|rcsb pdb:4JK2|rcsb pdb:4KMU|rcsb pdb:4KN4|rcsb pdb:4KN7|rcsb pdb:4MEX|rcsb pdb:4MEY|rcsb pdb:4XSX|rcsb pdb:4XSY|rcsb pdb:4XSZ|rcsb pdb:4YG2|rcsb pdb:4YLN|ensemblbacteria:AAC76962(transcript)|ensemblbacteria:b3988(gene)|ensemblbacteria:BAE77332(gene)|ensemblbacteria:BAE77332(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0046677"(response to antibiotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|refseq:NP_418415.1|rcsb pdb:4YLP|rcsb pdb:4ZH2|rcsb pdb:4ZH3|rcsb pdb:4ZH4|rcsb pdb:5BYH|rcsb pdb:5EZK|rcsb pdb:5IPL|rcsb pdb:5IPM|rcsb pdb:5IPN|rcsb pdb:5MS0|rcsb pdb:5MY1|rcsb pdb:5NSR|rcsb pdb:5NSS|rcsb pdb:5NWT|rcsb pdb:5UAC|rcsb pdb:5UAG|rcsb pdb:5UAH|rcsb pdb:5UAJ|rcsb pdb:5UAL|rcsb pdb:5UAQ|rcsb pdb:5VSW|rcsb pdb:5VT0|rcsb pdb:5W1S|rcsb pdb:5W1T|rcsb pdb:6ALF|rcsb pdb:6ALG|rcsb pdb:6ALH|rcsb pdb:6ASX|rcsb pdb:6BJS|rcsb pdb:6BYU|rcsb pdb:6C6S|rcsb pdb:6C6T|rcsb pdb:6C6U|rcsb pdb:6C9Y|rcsb pdb:6CA0|rcsb pdb:6CUX|rcsb pdb:6FLP|rcsb pdb:6FLQ|rcsb pdb:6GFW|rcsb pdb:6GH5|rcsb pdb:6GH6|rcsb pdb:6JBQ|rcsb pdb:6JNX|rcsb pdb:6K4Y|rcsb pdb:6KJ6|rcsb pdb:6LDI|rcsb pdb:6N4C|rcsb pdb:6N57|rcsb pdb:6N58|rcsb pdb:6N60|rcsb pdb:6N61|rcsb pdb:6OMF|rcsb pdb:6P18|rcsb pdb:6P19|rcsb pdb:6P1K|rcsb pdb:6PSQ|rcsb pdb:6PSR|rcsb pdb:6PSS|rcsb pdb:6PST|rcsb pdb:6PSU|rcsb pdb:6PSV|rcsb pdb:6PSW|rcsb pdb:6R9B|rcsb pdb:6R9G|rcsb pdb:6RH3|rcsb pdb:6RI7|rcsb pdb:6RI9|rcsb pdb:6RIN|rcsb pdb:6RIP|rcsb pdb:6TQN|rcsb pdb:6TQO|rcsb pdb:6UTV|rcsb pdb:6UTW|rcsb pdb:6UTX|rcsb pdb:6UTY|rcsb pdb:6UTZ|rcsb pdb:6UU0|rcsb pdb:6UU1|rcsb pdb:6UU2|rcsb pdb:6UU3|rcsb pdb:6UU4|rcsb pdb:6UU5|rcsb pdb:6UU6|rcsb pdb:6UU7|rcsb pdb:6UU8|rcsb pdb:6UU9|rcsb pdb:6UUA|rcsb pdb:6UUB|rcsb pdb:6UUC|rcsb pdb:6VJS|rcsb pdb:6WMU|rcsb pdb:6XAS|rcsb pdb:6XAV|rcsb pdb:7C17|rcsb pdb:7C97|rcsb pdb:7CHW|rcsb pdb:7KHB|rcsb pdb:7KHC|rcsb pdb:7KHE|rcsb pdb:7KHI|refseq:WP_000653944.1|dip:DIP-35803N|rcsb pdb:4YLO refseq:NP_417754.1|refseq:WP_001162094.1|ensemblbacteria:AAC76320(transcript)|ensemblbacteria:b3295(gene)|rcsb pdb:5NSS|ensemblbacteria:BAE77996(gene)|ensemblbacteria:BAE77996(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011260(RNA polymerase, alpha subunit, C-terminal)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR011773(DNA-directed RNA polymerase, alpha subunit)|interpro:IPR036603|interpro:IPR036643|rcsb pdb:1BDF|rcsb pdb:1COO|rcsb pdb:1LB2|rcsb pdb:1XS9|rcsb pdb:3IYD|rcsb pdb:3K4G|rcsb pdb:3LU0|rcsb pdb:3N4M|rcsb pdb:3N97|rcsb pdb:4JK1|rcsb pdb:4JK2|rcsb pdb:4KMU|rcsb pdb:4KN4|rcsb pdb:4KN7|rcsb pdb:4MEX|rcsb pdb:4MEY|rcsb pdb:4S20|rcsb pdb:4XSX|rcsb pdb:4XSY|rcsb pdb:4XSZ|rcsb pdb:4YG2|rcsb pdb:4YLN|rcsb pdb:4YLO|rcsb pdb:4YLP|rcsb pdb:4ZH2|rcsb pdb:4ZH3|rcsb pdb:4ZH4|rcsb pdb:5BYH|rcsb pdb:5CIZ|rcsb pdb:5EZK|rcsb pdb:5IPL|rcsb pdb:5IPM|rcsb pdb:5IPN|rcsb pdb:5MS0|rcsb pdb:5MY1|rcsb pdb:5NSR|rcsb pdb:6C9Y|rcsb pdb:6CA0|rcsb pdb:6CUX|rcsb pdb:6FLP|rcsb pdb:6FLQ|rcsb pdb:6GFW|rcsb pdb:6GH5|rcsb pdb:6GH6|rcsb pdb:6JBQ|rcsb pdb:6C6U|rcsb pdb:6JNX|rcsb pdb:6K4Y|rcsb pdb:6KJ6|rcsb pdb:6LDI|rcsb pdb:6N4C|rcsb pdb:6N57|rcsb pdb:6N58|rcsb pdb:6N60|rcsb pdb:6N61|rcsb pdb:6OMF|rcsb pdb:5NWT|rcsb pdb:5UAC|rcsb pdb:5UAG|rcsb pdb:5UAH|rcsb pdb:5UAJ|rcsb pdb:5UAL|rcsb pdb:5UAQ|rcsb pdb:5VSW|rcsb pdb:5VT0|rcsb pdb:5W1S|rcsb pdb:5W1T|rcsb pdb:6ALF|rcsb pdb:6ALG|rcsb pdb:6ALH|rcsb pdb:6ASX|rcsb pdb:6BJS|rcsb pdb:6BYU|rcsb pdb:6C6S|rcsb pdb:6C6T|rcsb pdb:6P18|rcsb pdb:6P19|rcsb pdb:6P1K|rcsb pdb:6PB4|rcsb pdb:6PB5|rcsb pdb:6PB6|rcsb pdb:6PMI|rcsb pdb:6PMJ|rcsb pdb:6PSQ|rcsb pdb:6PSR|rcsb pdb:6PSS|rcsb pdb:6PST|rcsb pdb:6PSU|rcsb pdb:6PSV|rcsb pdb:6PSW|rcsb pdb:6R9B|rcsb pdb:6R9G|rcsb pdb:6OUL|rcsb pdb:6RH3|rcsb pdb:6RI7|rcsb pdb:6RI9|rcsb pdb:6RIN|rcsb pdb:6TQN|rcsb pdb:6TQO|rcsb pdb:6UTW|rcsb pdb:6UTX|rcsb pdb:6UTY|rcsb pdb:6UU5|rcsb pdb:6UU6|rcsb pdb:6UU7|rcsb pdb:6UU8|rcsb pdb:6UUB|rcsb pdb:6VJS|rcsb pdb:6XAS|rcsb pdb:6XAV|rcsb pdb:6Z9P|rcsb pdb:6Z9Q|rcsb pdb:6Z9R|rcsb pdb:6Z9S|rcsb pdb:6Z9T|rcsb pdb:6ZTJ|rcsb pdb:6ZTL|rcsb pdb:6ZTM|rcsb pdb:6ZTN|rcsb pdb:6ZTO|rcsb pdb:6ZTP|rcsb pdb:6ZU1|rcsb pdb:6RIP|rcsb pdb:7ADB|rcsb pdb:7ADC|rcsb pdb:7ADD|rcsb pdb:7ADE|rcsb pdb:7C17|rcsb pdb:7C97|rcsb pdb:7CHW|rcsb pdb:7KHB|rcsb pdb:7KHC|rcsb pdb:7KHE|rcsb pdb:7KHI|mint:P0A7Z4|dip:DIP-35879N - - - figure legend:4|variable_condition:stationary phase|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/11/20 2014/10/16 rogid:uZC9aRrl+QIT7zZtcO7WPVedhnA83333 rogid:dpkf3DEbQiGwW9FbFES7hFqgs0E83333 intact-crc:20974055F1235303|rigid:xuGNIud7E9hl/2oiJJ8b+e+rrWk false mutation decreasing interaction:293-293|mutation decreasing interaction:275-275|mutation decreasing interaction:295-295|mutation decreasing interaction:302-302|his tag:?-?|mutation increasing interaction:300-300 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)