#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P50642 uniprotkb:P50644 intact:EBI-7231398|intact:MINT-6732615 intact:EBI-7231412|intact:MINT-6732622 psi-mi:rir1_ehv4(display_long)|uniprotkb:RIR1(gene name)|psi-mi:RIR1(display_short)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym) psi-mi:rir2_ehv4(display_long)|uniprotkb:RIR2(gene name)|psi-mi:RIR2(display_short)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Sun et al. (2000) pubmed:10727407|mint:MINT-6667072 taxid:10333(ehv-4)|taxid:10333("Equine herpesvirus 4 (strain 1942)") taxid:10333(ehv-4)|taxid:10333("Equine herpesvirus 4 (strain 1942)") psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-7231391|mint:MINT-6733354 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P50642|interpro:IPR034717|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019046"(release from viral latency)|interpro:IPR039718|mint:MINT-6733355(identity)|uniprotkb:P50642(P50642) interpro:IPR030475|interpro:IPR012348(Ribonucleotide reductase-related)|mint:P50644|interpro:IPR034715|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0006260"(DNA replication)|go:"GO:0009186"(deoxyribonucleoside diphosphate metabolic process)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0033644"(host cell membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR033909|mint:MINT-6733358(identity)|uniprotkb:P50644(P50644) - comment:mint|function:Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides comment:mint|function:Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation taxid:-3(unknown)|taxid:-3(Unknown) - 2008/07/25 2014/10/16 rogid:WrURKccFFtbf8kMS9rB+yCuzR+c10333 rogid:nqeNLVH1FdD7cES4wsLBF0Exsc810333 intact-crc:F642158AEC4A8E07|rigid:8e3KR1ozpB0lnsA5vRklVassdPI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50644 uniprotkb:P08543 intact:EBI-7231412|intact:MINT-6732622 intact:EBI-7231433|intact:MINT-6732628|uniprotkb:Q09I94|uniprotkb:B9VQG7 psi-mi:rir2_ehv4(display_long)|uniprotkb:RIR2(gene name)|psi-mi:RIR2(display_short)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym) psi-mi:rir1_hhv11(display_long)|uniprotkb:RIR1(gene name)|psi-mi:RIR1(display_short)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:UL39(locus name)|uniprotkb:ICP6(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Sun et al. (2000) pubmed:10727407|mint:MINT-6667072 taxid:10333(ehv-4)|taxid:10333("Equine herpesvirus 4 (strain 1942)") taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-7231455|mint:MINT-6733361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030475|interpro:IPR012348(Ribonucleotide reductase-related)|mint:P50644|interpro:IPR034715|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0006260"(DNA replication)|go:"GO:0009186"(deoxyribonucleoside diphosphate metabolic process)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0033644"(host cell membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR033909|mint:MINT-6733362(identity)|uniprotkb:P50644(P50644) mint:P08543|refseq:YP_009137114.1|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0019046"(release from viral latency)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR034717|interpro:IPR039718|reactome:R-HSA-5213460|reactome:R-HSA-9686347|dip:DIP-57653N|mint:MINT-6733365(identity)|uniprotkb:P08543(P08543) - comment:mint|function:Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides comment:mint|function:Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation taxid:-3(unknown)|taxid:-3(Unknown) - 2008/07/25 2014/10/16 rogid:nqeNLVH1FdD7cES4wsLBF0Exsc810333 rogid:/pZ7FfoT7LnfA9jeZfRa49yakrc10299 intact-crc:69B5C2870D3261FF|rigid:sHUqfjECtihkdj4ESkRIs2JZEiM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08543 uniprotkb:P10224 intact:EBI-7231433|intact:MINT-6732628|uniprotkb:Q09I94|uniprotkb:B9VQG7 intact:EBI-7231490|uniprotkb:B9VQG8|intact:MINT-6732638|uniprotkb:Q09I93 psi-mi:rir1_hhv11(display_long)|uniprotkb:RIR1(gene name)|psi-mi:RIR1(display_short)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:UL39(locus name)|uniprotkb:ICP6(gene name synonym) psi-mi:rir2_hhv11(display_long)|uniprotkb:RIR2(gene name)|psi-mi:RIR2(display_short)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym)|uniprotkb:UL40(orf name) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Sun et al. (2000) pubmed:10727407|mint:MINT-6667072 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-7231518|mint:MINT-6733375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P08543|refseq:YP_009137114.1|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0019046"(release from viral latency)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR034717|interpro:IPR039718|reactome:R-HSA-5213460|reactome:R-HSA-9686347|dip:DIP-57653N|mint:MINT-6733376(identity)|uniprotkb:P08543(P08543) interpro:IPR030475|interpro:IPR012348(Ribonucleotide reductase-related)|mint:P10224|refseq:YP_009137115.1|interpro:IPR034715|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0006260"(DNA replication)|go:"GO:0009186"(deoxyribonucleoside diphosphate metabolic process)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0033644"(host cell membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR033909|mint:MINT-6733379(identity)|uniprotkb:P10224(P10224) - comment:mint|function:Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides comment:mint|function:Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation taxid:-3(unknown)|taxid:-3(Unknown) - 2008/07/25 2014/10/16 rogid:/pZ7FfoT7LnfA9jeZfRa49yakrc10299 rogid:WZoYdXaUWQwLTA9Rcjjuydvv1Bk10299 intact-crc:3704F19AF8112E4D|rigid:DonVL42zydHypFMW6CBwp0JzEok false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50642 uniprotkb:P10224 intact:EBI-7231398|intact:MINT-6732615 intact:EBI-7231490|uniprotkb:B9VQG8|intact:MINT-6732638|uniprotkb:Q09I93 psi-mi:rir1_ehv4(display_long)|uniprotkb:RIR1(gene name)|psi-mi:RIR1(display_short)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym) psi-mi:rir2_hhv11(display_long)|uniprotkb:RIR2(gene name)|psi-mi:RIR2(display_short)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym)|uniprotkb:UL40(orf name) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Sun et al. (2000) pubmed:10727407|mint:MINT-6667072 taxid:10333(ehv-4)|taxid:10333("Equine herpesvirus 4 (strain 1942)") taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-7231483|mint:MINT-6733368 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P50642|interpro:IPR034717|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019046"(release from viral latency)|interpro:IPR039718|mint:MINT-6733372(identity)|uniprotkb:P50642(P50642) interpro:IPR030475|interpro:IPR012348(Ribonucleotide reductase-related)|mint:P10224|refseq:YP_009137115.1|interpro:IPR034715|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0006260"(DNA replication)|go:"GO:0009186"(deoxyribonucleoside diphosphate metabolic process)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0033644"(host cell membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR033909|mint:MINT-6733369(identity)|uniprotkb:P10224(P10224) - comment:mint|function:Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides comment:mint|function:Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation taxid:-3(unknown)|taxid:-3(Unknown) - 2008/07/25 2014/10/16 rogid:WrURKccFFtbf8kMS9rB+yCuzR+c10333 rogid:WZoYdXaUWQwLTA9Rcjjuydvv1Bk10299 intact-crc:E5BCEF920409E6CF|rigid:NOyE2JXbQLMb3IwkMbjWQSVMnVI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)