#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q03392	uniprotkb:Q03392	intact:EBI-768724|ensemblfungi:"SPBC16D10.09.1:pep"	intact:EBI-768724|ensemblfungi:"SPBC16D10.09.1:pep"	psi-mi:pcna_schpo(display_long)|uniprotkb:pcn1(gene name)|psi-mi:pcn1(display_short)|uniprotkb:pcn(gene name synonym)|uniprotkb:SPBC16D10.09(orf name)	psi-mi:pcna_schpo(display_long)|uniprotkb:pcn1(gene name)|psi-mi:pcn1(display_short)|uniprotkb:pcn(gene name synonym)|uniprotkb:SPBC16D10.09(orf name)	psi-mi:"MI:0018"(two hybrid)	Reynolds et al. (2000)	pubmed:10698951|imex:IM-19288	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2104952|imex:IM-19288-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|refseq:NP_596504.1|reactome:R-SPO-4615885|reactome:R-SPO-110312|reactome:R-SPO-69183|reactome:R-SPO-110314|reactome:R-SPO-110320|reactome:R-SPO-5358565|reactome:R-SPO-5651801|reactome:R-SPO-5655862|reactome:R-SPO-5656121|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|dip:DIP-33811N|ensemblfungi:SPBC16D10.09(gene)|ensemblfungi:SPBC16D10.09.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:6QH1|reactome:R-SPO-174437|reactome:R-SPO-8866654	reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|refseq:NP_596504.1|reactome:R-SPO-4615885|reactome:R-SPO-110312|reactome:R-SPO-69183|reactome:R-SPO-110314|reactome:R-SPO-110320|reactome:R-SPO-5358565|reactome:R-SPO-5651801|reactome:R-SPO-5655862|reactome:R-SPO-5656121|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|dip:DIP-33811N|ensemblfungi:SPBC16D10.09(gene)|ensemblfungi:SPBC16D10.09.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:6QH1|reactome:R-SPO-174437|reactome:R-SPO-8866654	-	crc64:1EE5B2A27A899C4E	crc64:1EE5B2A27A899C4E	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/07	2014/10/16	rogid:k/4DTGZyB+IVI6lIKluopAMVgUI284812	rogid:k/4DTGZyB+IVI6lIKluopAMVgUI284812	intact-crc:263A23479A38B8FD|rigid:++DbgaZ20J2N6TBC2NAg9MxtGH0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03392	uniprotkb:P30261	intact:EBI-768724|ensemblfungi:"SPBC16D10.09.1:pep"	intact:EBI-866919|ensemblfungi:"SPBC1734.02c.1:pep"	psi-mi:pcna_schpo(display_long)|uniprotkb:pcn1(gene name)|psi-mi:pcn1(display_short)|uniprotkb:pcn(gene name synonym)|uniprotkb:SPBC16D10.09(orf name)	psi-mi:dpod3_schpo(display_long)|uniprotkb:Cell division control protein 27(gene name synonym)|uniprotkb:cdc27(gene name)|psi-mi:cdc27(display_short)|uniprotkb:SPBC1734.02c(orf name)|uniprotkb:SPBC337.18c(orf name)	psi-mi:"MI:0018"(two hybrid)	Reynolds et al. (2000)	pubmed:10698951|imex:IM-19288	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2104955|imex:IM-19288-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|refseq:NP_596504.1|reactome:R-SPO-4615885|reactome:R-SPO-110312|reactome:R-SPO-69183|reactome:R-SPO-110314|reactome:R-SPO-110320|reactome:R-SPO-5358565|reactome:R-SPO-5651801|reactome:R-SPO-5655862|reactome:R-SPO-5656121|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|dip:DIP-33811N|ensemblfungi:SPBC16D10.09(gene)|ensemblfungi:SPBC16D10.09.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:6QH1|reactome:R-SPO-174437|reactome:R-SPO-8866654	interpro:IPR019038|refseq:NP_595419.1|interpro:IPR041913|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|ensemblfungi:SPBC1734.02c(gene)|ensemblfungi:SPBC1734.02c.1(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0051301"(cell division)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606	-	crc64:1EE5B2A27A899C4E	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/07	2014/10/16	rogid:k/4DTGZyB+IVI6lIKluopAMVgUI284812	rogid:+Zip79Iba8IaiD7hrbZjOcjEroU284812	intact-crc:D6A23ABA88E1854B|rigid:+uHUwEujS+ugz8MKsJ2tbQfaiTw	false	-	binding-associated region:173-372	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03392	uniprotkb:P30261	intact:EBI-768724|ensemblfungi:"SPBC16D10.09.1:pep"	intact:EBI-866919|ensemblfungi:"SPBC1734.02c.1:pep"	psi-mi:pcna_schpo(display_long)|uniprotkb:pcn1(gene name)|psi-mi:pcn1(display_short)|uniprotkb:pcn(gene name synonym)|uniprotkb:SPBC16D10.09(orf name)	psi-mi:dpod3_schpo(display_long)|uniprotkb:Cell division control protein 27(gene name synonym)|uniprotkb:cdc27(gene name)|psi-mi:cdc27(display_short)|uniprotkb:SPBC1734.02c(orf name)|uniprotkb:SPBC337.18c(orf name)	psi-mi:"MI:0096"(pull down)	Reynolds et al. (2000)	pubmed:10698951|imex:IM-19288	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2104969|imex:IM-19288-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|refseq:NP_596504.1|reactome:R-SPO-4615885|reactome:R-SPO-110312|reactome:R-SPO-69183|reactome:R-SPO-110314|reactome:R-SPO-110320|reactome:R-SPO-5358565|reactome:R-SPO-5651801|reactome:R-SPO-5655862|reactome:R-SPO-5656121|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|dip:DIP-33811N|ensemblfungi:SPBC16D10.09(gene)|ensemblfungi:SPBC16D10.09.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:6QH1|reactome:R-SPO-174437|reactome:R-SPO-8866654	interpro:IPR019038|refseq:NP_595419.1|interpro:IPR041913|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|ensemblfungi:SPBC1734.02c(gene)|ensemblfungi:SPBC1734.02c.1(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0051301"(cell division)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606	-	crc64:1EE5B2A27A899C4E	-	figure legend:1B-D|comment:GST-cdc27 constructs with a mutation of Gln-362 to Ala, Val, Asp, Glu, Asn or Lys also interact.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/07	2014/10/16	rogid:k/4DTGZyB+IVI6lIKluopAMVgUI284812	rogid:+Zip79Iba8IaiD7hrbZjOcjEroU284812	intact-crc:5D71B6123EBAD0EA|rigid:+uHUwEujS+ugz8MKsJ2tbQfaiTw	false	his tag:?-?	glutathione s tranferase tag:?-?|binding-associated region:333-372	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P30261	uniprotkb:Q03392	intact:EBI-866919|ensemblfungi:"SPBC1734.02c.1:pep"	intact:EBI-768724|ensemblfungi:"SPBC16D10.09.1:pep"	psi-mi:dpod3_schpo(display_long)|uniprotkb:Cell division control protein 27(gene name synonym)|uniprotkb:cdc27(gene name)|psi-mi:cdc27(display_short)|uniprotkb:SPBC1734.02c(orf name)|uniprotkb:SPBC337.18c(orf name)	psi-mi:pcna_schpo(display_long)|uniprotkb:pcn1(gene name)|psi-mi:pcn1(display_short)|uniprotkb:pcn(gene name synonym)|uniprotkb:SPBC16D10.09(orf name)	psi-mi:"MI:0096"(pull down)	Reynolds et al. (2000)	pubmed:10698951|imex:IM-19288	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2104980|imex:IM-19288-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR019038|refseq:NP_595419.1|interpro:IPR041913|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|ensemblfungi:SPBC1734.02c(gene)|ensemblfungi:SPBC1734.02c.1(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0051301"(cell division)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606	reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|refseq:NP_596504.1|reactome:R-SPO-4615885|reactome:R-SPO-110312|reactome:R-SPO-69183|reactome:R-SPO-110314|reactome:R-SPO-110320|reactome:R-SPO-5358565|reactome:R-SPO-5651801|reactome:R-SPO-5655862|reactome:R-SPO-5656121|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|dip:DIP-33811N|ensemblfungi:SPBC16D10.09(gene)|ensemblfungi:SPBC16D10.09.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:6QH1|reactome:R-SPO-174437|reactome:R-SPO-8866654	-	-	crc64:1EE5B2A27A899C4E	figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/07	2014/10/16	rogid:+Zip79Iba8IaiD7hrbZjOcjEroU284812	rogid:k/4DTGZyB+IVI6lIKluopAMVgUI284812	intact-crc:42290418FE521D23|rigid:+uHUwEujS+ugz8MKsJ2tbQfaiTw	false	N6-biotinyl-L-lysine:88-88|binding-associated region:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P87324	uniprotkb:P30261	intact:EBI-865227|ensemblfungi:"SPAC27E2.05.1:pep"	intact:EBI-866919|ensemblfungi:"SPBC1734.02c.1:pep"	psi-mi:dpod2_schpo(display_long)|uniprotkb:cdc1(gene name)|psi-mi:cdc1(display_short)|uniprotkb:SPAC27E2.05(orf name)	psi-mi:dpod3_schpo(display_long)|uniprotkb:Cell division control protein 27(gene name synonym)|uniprotkb:cdc27(gene name)|psi-mi:cdc27(display_short)|uniprotkb:SPBC1734.02c(orf name)|uniprotkb:SPBC337.18c(orf name)	psi-mi:"MI:0096"(pull down)	Reynolds et al. (2000)	pubmed:10698951|imex:IM-19288	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105062|imex:IM-19288-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR024826|refseq:NP_594406.1|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR040663|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|interpro:IPR041863|ensemblfungi:SPAC27E2.05(gene)|ensemblfungi:SPAC27E2.05.1(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0042575"(DNA polymerase complex)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0051301"(cell division)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606	interpro:IPR019038|refseq:NP_595419.1|interpro:IPR041913|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|ensemblfungi:SPBC1734.02c(gene)|ensemblfungi:SPBC1734.02c.1(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0051301"(cell division)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606	-	-	-	figure legend:7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/07	2014/10/16	rogid:WcVki8A+hnyld55ylIQ4PeDhOuk284812	rogid:+Zip79Iba8IaiD7hrbZjOcjEroU284812	intact-crc:FAD668CBFA263769|rigid:eOQhqrJnFhbXppqe+0+WOBglNPk	false	35s radiolabel:?-?	binding-associated region:1-159|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P30261	uniprotkb:Q03392	intact:EBI-866919|ensemblfungi:"SPBC1734.02c.1:pep"	intact:EBI-768724|ensemblfungi:"SPBC16D10.09.1:pep"	psi-mi:dpod3_schpo(display_long)|uniprotkb:Cell division control protein 27(gene name synonym)|uniprotkb:cdc27(gene name)|psi-mi:cdc27(display_short)|uniprotkb:SPBC1734.02c(orf name)|uniprotkb:SPBC337.18c(orf name)	psi-mi:pcna_schpo(display_long)|uniprotkb:pcn1(gene name)|psi-mi:pcn1(display_short)|uniprotkb:pcn(gene name synonym)|uniprotkb:SPBC16D10.09(orf name)	psi-mi:"MI:0096"(pull down)	Reynolds et al. (2000)	pubmed:10698951|imex:IM-19288	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105001|imex:IM-19288-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR019038|refseq:NP_595419.1|interpro:IPR041913|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|ensemblfungi:SPBC1734.02c(gene)|ensemblfungi:SPBC1734.02c.1(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0051301"(cell division)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606	reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|refseq:NP_596504.1|reactome:R-SPO-4615885|reactome:R-SPO-110312|reactome:R-SPO-69183|reactome:R-SPO-110314|reactome:R-SPO-110320|reactome:R-SPO-5358565|reactome:R-SPO-5651801|reactome:R-SPO-5655862|reactome:R-SPO-5656121|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|dip:DIP-33811N|ensemblfungi:SPBC16D10.09(gene)|ensemblfungi:SPBC16D10.09.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:6QH1|reactome:R-SPO-174437|reactome:R-SPO-8866654	-	-	crc64:1EE5B2A27A899C4E	delivery method:Q03392; P30261 transformation|figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2008/11/07	2014/10/16	rogid:+Zip79Iba8IaiD7hrbZjOcjEroU284812	rogid:k/4DTGZyB+IVI6lIKluopAMVgUI284812	intact-crc:DB934AD47716D040|rigid:+uHUwEujS+ugz8MKsJ2tbQfaiTw	false	ha tag:?-?	his tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q03392	uniprotkb:P30261	intact:EBI-768724|ensemblfungi:"SPBC16D10.09.1:pep"	intact:EBI-866919|ensemblfungi:"SPBC1734.02c.1:pep"	psi-mi:pcna_schpo(display_long)|uniprotkb:pcn1(gene name)|psi-mi:pcn1(display_short)|uniprotkb:pcn(gene name synonym)|uniprotkb:SPBC16D10.09(orf name)	psi-mi:dpod3_schpo(display_long)|uniprotkb:Cell division control protein 27(gene name synonym)|uniprotkb:cdc27(gene name)|psi-mi:cdc27(display_short)|uniprotkb:SPBC1734.02c(orf name)|uniprotkb:SPBC337.18c(orf name)	psi-mi:"MI:0096"(pull down)	Reynolds et al. (2000)	pubmed:10698951|imex:IM-19288	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105017|imex:IM-19288-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|refseq:NP_596504.1|reactome:R-SPO-4615885|reactome:R-SPO-110312|reactome:R-SPO-69183|reactome:R-SPO-110314|reactome:R-SPO-110320|reactome:R-SPO-5358565|reactome:R-SPO-5651801|reactome:R-SPO-5655862|reactome:R-SPO-5656121|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|dip:DIP-33811N|ensemblfungi:SPBC16D10.09(gene)|ensemblfungi:SPBC16D10.09.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:6QH1|reactome:R-SPO-174437|reactome:R-SPO-8866654	interpro:IPR019038|refseq:NP_595419.1|interpro:IPR041913|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|ensemblfungi:SPBC1734.02c(gene)|ensemblfungi:SPBC1734.02c.1(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0051301"(cell division)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606	-	crc64:1EE5B2A27A899C4E	-	comment:"cdc27 synthetic peptide of 20 aa (corresponding to c-terminus of native protein) has been used."|figure legend:5|comment:a cdc27 peptide bearing a corresponding glu362ala mutation also interacts.|antagonist:CDKN1A/p21, suggesting that cdc27 and CDKN1A share a common binding site on pcn1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/07	2014/10/16	rogid:k/4DTGZyB+IVI6lIKluopAMVgUI284812	rogid:+Zip79Iba8IaiD7hrbZjOcjEroU284812	intact-crc:6D3B8F81170044D9|rigid:+uHUwEujS+ugz8MKsJ2tbQfaiTw	false	-	binding-associated region:353-372	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q03392	uniprotkb:P38936	intact:EBI-768724|ensemblfungi:"SPBC16D10.09.1:pep"	intact:EBI-375077|uniprotkb:Q14010|uniprotkb:Q9BUT4|uniprotkb:Q6FI05|ensembl:ENSP00000244741|ensembl:ENSP00000362815|ensembl:ENSP00000384849|ensembl:ENSP00000409259|ensembl:ENSP00000482768	psi-mi:pcna_schpo(display_long)|uniprotkb:pcn1(gene name)|psi-mi:pcn1(display_short)|uniprotkb:pcn(gene name synonym)|uniprotkb:SPBC16D10.09(orf name)	psi-mi:cdn1a_human(display_long)|uniprotkb:CDKN1A(gene name)|psi-mi:CDKN1A(display_short)|uniprotkb:CAP20(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:CIP1(gene name synonym)|uniprotkb:MDA6(gene name synonym)|uniprotkb:PIC1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:WAF1(gene name synonym)|uniprotkb:p21(gene name synonym)|uniprotkb:CDK-interacting protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Reynolds et al. (2000)	pubmed:10698951|imex:IM-19288	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105025|imex:IM-19288-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|refseq:NP_596504.1|reactome:R-SPO-4615885|reactome:R-SPO-110312|reactome:R-SPO-69183|reactome:R-SPO-110314|reactome:R-SPO-110320|reactome:R-SPO-5358565|reactome:R-SPO-5651801|reactome:R-SPO-5655862|reactome:R-SPO-5656121|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|dip:DIP-33811N|ensemblfungi:SPBC16D10.09(gene)|ensemblfungi:SPBC16D10.09.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:6QH1|reactome:R-SPO-174437|reactome:R-SPO-8866654	refseq:NP_001278478.1|ensembl:ENSG00000124762(gene)|ensembl:ENST00000244741(transcript)|ensembl:ENST00000373711(transcript)|ensembl:ENST00000405375(transcript)|ensembl:ENST00000448526(transcript)|ensembl:ENST00000615513(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019912"(cyclin-dependent protein kinase activating kinase activity)|refseq:NP_000380.1|refseq:NP_001207706.1|refseq:NP_001207707.1|refseq:NP_510867.1|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029841|mint:P38936|rcsb pdb:1AXC|rcsb pdb:2ZVV|rcsb pdb:2ZVW|rcsb pdb:4RJF|rcsb pdb:5E0U|rcsb pdb:6CBI|rcsb pdb:6CEJ|rcsb pdb:6CIV|rcsb pdb:6CIX|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5674400|reactome:R-HSA-6785807|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8866911|reactome:R-HSA-8878166|reactome:R-HSA-8941855|reactome:R-HSA-9616222|reactome:R-HSA-9617828|reactome:R-HSA-9661069|reactome:R-HSA-9702518|reactome:R-HSA-9703465|dip:DIP-246N	-	crc64:1EE5B2A27A899C4E	-	comment:"CDKN1A/p21 synthetic peptide of 20 aa (corresponding to c-terminus of native protein) has been used."|figure legend:5|comment:a CDKN1A/p21 peptide bearing a corresponding glu144ala mutation also interacts.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/07	2014/10/16	rogid:k/4DTGZyB+IVI6lIKluopAMVgUI284812	rogid:9GjjylWSA7IM/g1ZUxNAKyFtCp49606	intact-crc:5693F6CB29E8A04B|rigid:/ytBgG07Pyb5GIO4cqW9J9tSe6Q	false	-	binding-associated region:141-160	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q03392	uniprotkb:P47110	intact:EBI-768724|ensemblfungi:"SPBC16D10.09.1:pep"	intact:EBI-6084|uniprotkb:D6VWL4|ensemblfungi:YJR043C	psi-mi:pcna_schpo(display_long)|uniprotkb:pcn1(gene name)|psi-mi:pcn1(display_short)|uniprotkb:pcn(gene name synonym)|uniprotkb:SPBC16D10.09(orf name)	psi-mi:dpod3_yeast(display_long)|uniprotkb:POL32(gene name)|psi-mi:POL32(display_short)|uniprotkb:J1626(orf name)|uniprotkb:YJR043C(locus name)	psi-mi:"MI:0096"(pull down)	Reynolds et al. (2000)	pubmed:10698951|imex:IM-19288	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105033|imex:IM-19288-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|refseq:NP_596504.1|reactome:R-SPO-4615885|reactome:R-SPO-110312|reactome:R-SPO-69183|reactome:R-SPO-110314|reactome:R-SPO-110320|reactome:R-SPO-5358565|reactome:R-SPO-5651801|reactome:R-SPO-5655862|reactome:R-SPO-5656121|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|dip:DIP-33811N|ensemblfungi:SPBC16D10.09(gene)|ensemblfungi:SPBC16D10.09.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:6QH1|reactome:R-SPO-174437|reactome:R-SPO-8866654	refseq:NP_012577.1|sgd:S000003804|dip:DIP-2523N|mint:P47110|ensemblfungi:YJR043C(gene)|ensemblfungi:YJR043C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006277"(DNA amplification)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|rcsb pdb:6P1H|rcsb pdb:6V8P|rcsb pdb:6V93|rcsb pdb:7LXD	-	crc64:1EE5B2A27A899C4E	crc64:D0B9CC52F26E20B2	comment:"Pol32 synthetic peptide of 20 aa (corresponding to c-terminus of native protein) has been used."|figure legend:5|comment:a Pol32 peptide bearing a corresponding glu338ala mutation also interacts.|antagonist:CDKN1A/p21, suggesting that Pol32 and CDKN1A share a common binding site on pcn1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/07	2014/10/16	rogid:k/4DTGZyB+IVI6lIKluopAMVgUI284812	rogid:02A0trLDLwbbYcE+AONHGaJ/XHM559292	intact-crc:C585D0002C4E1D03|rigid:NxJIPkJPIfHYKomI+OBmzUIT8zY	false	-	binding-associated region:331-350	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P87324	uniprotkb:P30261	intact:EBI-865227|ensemblfungi:"SPAC27E2.05.1:pep"	intact:EBI-866919|ensemblfungi:"SPBC1734.02c.1:pep"	psi-mi:dpod2_schpo(display_long)|uniprotkb:cdc1(gene name)|psi-mi:cdc1(display_short)|uniprotkb:SPAC27E2.05(orf name)	psi-mi:dpod3_schpo(display_long)|uniprotkb:Cell division control protein 27(gene name synonym)|uniprotkb:cdc27(gene name)|psi-mi:cdc27(display_short)|uniprotkb:SPBC1734.02c(orf name)|uniprotkb:SPBC337.18c(orf name)	psi-mi:"MI:0018"(two hybrid)	Reynolds et al. (2000)	pubmed:10698951|imex:IM-19288	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105050|imex:IM-19288-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR024826|refseq:NP_594406.1|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR040663|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|interpro:IPR041863|ensemblfungi:SPAC27E2.05(gene)|ensemblfungi:SPAC27E2.05.1(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0042575"(DNA polymerase complex)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0051301"(cell division)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606	interpro:IPR019038|refseq:NP_595419.1|interpro:IPR041913|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|ensemblfungi:SPBC1734.02c(gene)|ensemblfungi:SPBC1734.02c.1(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0051301"(cell division)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606	-	-	-	caution:Co-expressed cdc27 was necessary to activate LacZ expresion suggesting that it bridges the Gal4-Pcn1 and LexA-Cdcd1 fusion proteins.|figure legend:7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/07	2014/10/16	rogid:WcVki8A+hnyld55ylIQ4PeDhOuk284812	rogid:+Zip79Iba8IaiD7hrbZjOcjEroU284812	intact-crc:F44DE502D458550C|rigid:AnzkmlUBInWFXe8BmaK03zvIPAY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P87324	uniprotkb:Q03392	intact:EBI-865227|ensemblfungi:"SPAC27E2.05.1:pep"	intact:EBI-768724|ensemblfungi:"SPBC16D10.09.1:pep"	psi-mi:dpod2_schpo(display_long)|uniprotkb:cdc1(gene name)|psi-mi:cdc1(display_short)|uniprotkb:SPAC27E2.05(orf name)	psi-mi:pcna_schpo(display_long)|uniprotkb:pcn1(gene name)|psi-mi:pcn1(display_short)|uniprotkb:pcn(gene name synonym)|uniprotkb:SPBC16D10.09(orf name)	psi-mi:"MI:0018"(two hybrid)	Reynolds et al. (2000)	pubmed:10698951|imex:IM-19288	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105050|imex:IM-19288-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR024826|refseq:NP_594406.1|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR040663|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|interpro:IPR041863|ensemblfungi:SPAC27E2.05(gene)|ensemblfungi:SPAC27E2.05.1(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0042575"(DNA polymerase complex)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0051301"(cell division)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606	reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|refseq:NP_596504.1|reactome:R-SPO-4615885|reactome:R-SPO-110312|reactome:R-SPO-69183|reactome:R-SPO-110314|reactome:R-SPO-110320|reactome:R-SPO-5358565|reactome:R-SPO-5651801|reactome:R-SPO-5655862|reactome:R-SPO-5656121|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|dip:DIP-33811N|ensemblfungi:SPBC16D10.09(gene)|ensemblfungi:SPBC16D10.09.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:6QH1|reactome:R-SPO-174437|reactome:R-SPO-8866654	-	-	crc64:1EE5B2A27A899C4E	caution:Co-expressed cdc27 was necessary to activate LacZ expresion suggesting that it bridges the Gal4-Pcn1 and LexA-Cdcd1 fusion proteins.|figure legend:7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/07	2014/10/16	rogid:WcVki8A+hnyld55ylIQ4PeDhOuk284812	rogid:k/4DTGZyB+IVI6lIKluopAMVgUI284812	intact-crc:F44DE502D458550C|rigid:AnzkmlUBInWFXe8BmaK03zvIPAY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P87324	uniprotkb:P30261	intact:EBI-865227|ensemblfungi:"SPAC27E2.05.1:pep"	intact:EBI-866919|ensemblfungi:"SPBC1734.02c.1:pep"	psi-mi:dpod2_schpo(display_long)|uniprotkb:cdc1(gene name)|psi-mi:cdc1(display_short)|uniprotkb:SPAC27E2.05(orf name)	psi-mi:dpod3_schpo(display_long)|uniprotkb:Cell division control protein 27(gene name synonym)|uniprotkb:cdc27(gene name)|psi-mi:cdc27(display_short)|uniprotkb:SPBC1734.02c(orf name)|uniprotkb:SPBC337.18c(orf name)	psi-mi:"MI:0018"(two hybrid)	Reynolds et al. (2000)	pubmed:10698951|imex:IM-19288	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2105056|imex:IM-19288-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR024826|refseq:NP_594406.1|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR040663|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|interpro:IPR041863|ensemblfungi:SPAC27E2.05(gene)|ensemblfungi:SPAC27E2.05.1(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0042575"(DNA polymerase complex)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0051301"(cell division)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606	interpro:IPR019038|refseq:NP_595419.1|interpro:IPR041913|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|ensemblfungi:SPBC1734.02c(gene)|ensemblfungi:SPBC1734.02c.1(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0051301"(cell division)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606	-	-	-	figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/11/07	2014/10/16	rogid:WcVki8A+hnyld55ylIQ4PeDhOuk284812	rogid:+Zip79Iba8IaiD7hrbZjOcjEroU284812	intact-crc:7B7E5367AD4A1FD2|rigid:eOQhqrJnFhbXppqe+0+WOBglNPk	false	-	binding-associated region:1-159	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)