#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q7K9Q9 uniprotkb:P92177 intact:EBI-867471|ensemblmetazoa:FBpp0099807 intact:EBI-204478|uniprotkb:Q8IN86|intact:EBI-458717|uniprotkb:Q8IN87|uniprotkb:Q9VEA8|ensemblmetazoa:FBpp0082987 psi-mi:q7k9q9_drome(display_long)|uniprotkb:par-1(gene name)|psi-mi:par-1(display_short)|uniprotkb:CG8201(orf name) psi-mi:1433e_drome(display_long)|uniprotkb:14-3-3epsilon(gene name)|psi-mi:14-3-3epsilon(display_short)|uniprotkb:14-3-3e(gene name synonym)|uniprotkb:SR3-9(gene name synonym)|uniprotkb:Suppressor of Ras1 3-9(gene name synonym)|uniprotkb:CG31196(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871054 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0260934|ensemblmetazoa:FBgn0260934(gene)|ensemblmetazoa:FBtr0100393(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0009798"(axis specification)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030709"(border follicle cell delamination)|go:"GO:0030860"(regulation of polarized epithelial cell differentiation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045169"(fusome)|go:"GO:0045172"(germline ring canal)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity) refseq:NP_732309.1|refseq:NP_732310.1|refseq:NP_732311.1|refseq:NP_732312.1|flybase:FBgn0020238|dip:DIP-18498N|ensemblmetazoa:FBgn0020238(gene)|ensemblmetazoa:FBtr0083565(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007280"(pole cell migration)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009411"(response to UV)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040008"(regulation of growth)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045172"(germline ring canal)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0150013"(negative regulation of neuron projection arborization)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P92177|reactome:R-DME-2028269|reactome:R-DME-3371453|reactome:R-DME-3371511|reactome:R-DME-390098|reactome:R-DME-432553|reactome:R-DME-5625740|reactome:R-DME-5628897|reactome:R-DME-75035|reactome:R-DME-8876198 pubmed:12431373(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Omcx4yx4w1yGPngw1s7ClWPmCZs7227 rogid:VyaKt/NXQIB+SaXr0gONlnAU1ws7227 intact-crc:AB15F0ACBC18B33F|rigid:l+4EOWfC49R664HoA+KxJen9Bc0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8IPH9 uniprotkb:P29310 intact:EBI-142379|uniprotkb:O61564|uniprotkb:Q95SL3|uniprotkb:Q9VLZ4|uniprotkb:Q5BIJ6|ensemblmetazoa:FBpp0303540|ensemblmetazoa:FBpp0303542 intact:EBI-198100|intact:EBI-1630797|uniprotkb:A4UZB2|uniprotkb:A4UZB3|uniprotkb:O01665|uniprotkb:Q0E9D5|uniprotkb:Q0E9D6|uniprotkb:Q0E9D7|uniprotkb:Q8IGB9|uniprotkb:Q8MKV5|uniprotkb:Q9V5G6|uniprotkb:C1C593|uniprotkb:C9QP27|ensemblmetazoa:FBpp0087502|ensemblmetazoa:FBpp0087503|ensemblmetazoa:FBpp0099540|ensemblmetazoa:FBpp0305136|ensemblmetazoa:FBpp0305137 psi-mi:slob_drome(display_long)|uniprotkb:Slob(gene name)|psi-mi:Slob(display_short)|uniprotkb:CG43756(orf name) psi-mi:1433z_drome(display_long)|uniprotkb:14-3-3zeta(gene name)|psi-mi:14-3-3zeta(display_short)|uniprotkb:14-3-3EZ(gene name synonym)|uniprotkb:leo(gene name synonym)|uniprotkb:14-3-3(gene name synonym)|uniprotkb:THAP(gene name synonym)|uniprotkb:CG17870(orf name)|uniprotkb:14-3-3-like protein(gene name synonym)|uniprotkb:Protein Leonardo(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871058 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0264087|refseq:NP_001033881.1|refseq:NP_001188710.1|refseq:NP_477349.1|refseq:NP_723292.1|refseq:NP_723293.1|ensemblmetazoa:FBgn0264087(gene)|ensemblmetazoa:FBtr0330697(transcript)|ensemblmetazoa:FBtr0330699(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042594"(response to starvation)|go:"GO:0043271"(negative regulation of ion transport)|go:"GO:0045202"(synapse)|go:"GO:0050804"(modulation of chemical synaptic transmission)|interpro:IPR011009(Protein kinase-like) refseq:NP_001260845.1|refseq:NP_001260846.1|refseq:NP_001014515.1|refseq:NP_001014516.1|refseq:NP_476885.2|refseq:NP_724884.1|refseq:NP_724885.1|refseq:NP_724886.1|refseq:NP_724887.2|refseq:NP_724888.2|refseq:NP_724889.2|refseq:NP_995792.1|flybase:FBgn0004907|dip:DIP-17371N|ensemblmetazoa:FBgn0004907(gene)|ensemblmetazoa:FBtr0088414(transcript)|ensemblmetazoa:FBtr0088415(transcript)|ensemblmetazoa:FBtr0100183(transcript)|ensemblmetazoa:FBtr0332916(transcript)|ensemblmetazoa:FBtr0332917(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045172"(germline ring canal)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0120176"(positive regulation of torso signaling pathway)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-170968|reactome:R-DME-2028269|reactome:R-DME-3769402|reactome:R-DME-390098|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-450385|reactome:R-DME-450513|reactome:R-DME-450604|reactome:R-DME-5625740|reactome:R-DME-5628897|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6804114|reactome:R-DME-75035|reactome:R-DME-9013700|reactome:R-DME-9614399 pubmed:12529354(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:l3TJmhm+mVIuo4XzeG7+wVRY1YI7227 rogid:G1jZJfZZqZwEu9lekPYYdvZAXO87227 intact-crc:B0881875F664425A|rigid:UMP1D2cgvFyw9DZ5tsIZrEloZUE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P11346 uniprotkb:P29310 intact:EBI-664624|uniprotkb:Q9W4Z3|uniprotkb:Q8I086|uniprotkb:Q8I0D9|uniprotkb:Q8ISE1|uniprotkb:Q8ISE2|uniprotkb:Q8ISE3|uniprotkb:Q9NEH9|uniprotkb:A8JUV5|uniprotkb:Q0KHW7|ensemblmetazoa:FBpp0070385|ensemblmetazoa:FBpp0310458 intact:EBI-198100|intact:EBI-1630797|uniprotkb:A4UZB2|uniprotkb:A4UZB3|uniprotkb:O01665|uniprotkb:Q0E9D5|uniprotkb:Q0E9D6|uniprotkb:Q0E9D7|uniprotkb:Q8IGB9|uniprotkb:Q8MKV5|uniprotkb:Q9V5G6|uniprotkb:C1C593|uniprotkb:C9QP27|ensemblmetazoa:FBpp0087502|ensemblmetazoa:FBpp0087503|ensemblmetazoa:FBpp0099540|ensemblmetazoa:FBpp0305136|ensemblmetazoa:FBpp0305137 psi-mi:kraf1_drome(display_long)|uniprotkb:Raf(gene name)|psi-mi:Raf(display_short)|uniprotkb:Protein pole-hole(gene name synonym)|uniprotkb:ph(gene name synonym)|uniprotkb:phl(gene name synonym)|uniprotkb:CG2845(orf name) psi-mi:1433z_drome(display_long)|uniprotkb:14-3-3zeta(gene name)|psi-mi:14-3-3zeta(display_short)|uniprotkb:14-3-3EZ(gene name synonym)|uniprotkb:leo(gene name synonym)|uniprotkb:14-3-3(gene name synonym)|uniprotkb:THAP(gene name synonym)|uniprotkb:CG17870(orf name)|uniprotkb:14-3-3-like protein(gene name synonym)|uniprotkb:Protein Leonardo(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871062 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525047.1|flybase:FBgn0003079|refseq:NP_001096867.3|dip:DIP-29769N|ensemblmetazoa:FBgn0003079(gene)|ensemblmetazoa:FBtr0070401(transcript)|ensemblmetazoa:FBtr0344007(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0002168"(instar larval development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007552"(metamorphosis)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042386"(hemocyte differentiation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029071|reactome:R-DME-1295596|reactome:R-DME-170968|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-432553|reactome:R-DME-5621575|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5675482 refseq:NP_001260845.1|refseq:NP_001260846.1|refseq:NP_001014515.1|refseq:NP_001014516.1|refseq:NP_476885.2|refseq:NP_724884.1|refseq:NP_724885.1|refseq:NP_724886.1|refseq:NP_724887.2|refseq:NP_724888.2|refseq:NP_724889.2|refseq:NP_995792.1|flybase:FBgn0004907|dip:DIP-17371N|ensemblmetazoa:FBgn0004907(gene)|ensemblmetazoa:FBtr0088414(transcript)|ensemblmetazoa:FBtr0088415(transcript)|ensemblmetazoa:FBtr0100183(transcript)|ensemblmetazoa:FBtr0332916(transcript)|ensemblmetazoa:FBtr0332917(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045172"(germline ring canal)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0120176"(positive regulation of torso signaling pathway)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-170968|reactome:R-DME-2028269|reactome:R-DME-3769402|reactome:R-DME-390098|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-450385|reactome:R-DME-450513|reactome:R-DME-450604|reactome:R-DME-5625740|reactome:R-DME-5628897|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6804114|reactome:R-DME-75035|reactome:R-DME-9013700|reactome:R-DME-9614399 pubmed:9232600(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:rbvsd7+5RvYrFoXyonEM6Li84hM7227 rogid:G1jZJfZZqZwEu9lekPYYdvZAXO87227 intact-crc:031E5B1F8D857BCF|rigid:XN84d2N/V5tZlCEOJ+g0wF3QJZA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7K9Q9 uniprotkb:P29310 intact:EBI-867471|ensemblmetazoa:FBpp0099807 intact:EBI-198100|intact:EBI-1630797|uniprotkb:A4UZB2|uniprotkb:A4UZB3|uniprotkb:O01665|uniprotkb:Q0E9D5|uniprotkb:Q0E9D6|uniprotkb:Q0E9D7|uniprotkb:Q8IGB9|uniprotkb:Q8MKV5|uniprotkb:Q9V5G6|uniprotkb:C1C593|uniprotkb:C9QP27|ensemblmetazoa:FBpp0087502|ensemblmetazoa:FBpp0087503|ensemblmetazoa:FBpp0099540|ensemblmetazoa:FBpp0305136|ensemblmetazoa:FBpp0305137 psi-mi:q7k9q9_drome(display_long)|uniprotkb:par-1(gene name)|psi-mi:par-1(display_short)|uniprotkb:CG8201(orf name) psi-mi:1433z_drome(display_long)|uniprotkb:14-3-3zeta(gene name)|psi-mi:14-3-3zeta(display_short)|uniprotkb:14-3-3EZ(gene name synonym)|uniprotkb:leo(gene name synonym)|uniprotkb:14-3-3(gene name synonym)|uniprotkb:THAP(gene name synonym)|uniprotkb:CG17870(orf name)|uniprotkb:14-3-3-like protein(gene name synonym)|uniprotkb:Protein Leonardo(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871066 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0260934|ensemblmetazoa:FBgn0260934(gene)|ensemblmetazoa:FBtr0100393(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0009798"(axis specification)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030709"(border follicle cell delamination)|go:"GO:0030860"(regulation of polarized epithelial cell differentiation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045169"(fusome)|go:"GO:0045172"(germline ring canal)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity) refseq:NP_001260845.1|refseq:NP_001260846.1|refseq:NP_001014515.1|refseq:NP_001014516.1|refseq:NP_476885.2|refseq:NP_724884.1|refseq:NP_724885.1|refseq:NP_724886.1|refseq:NP_724887.2|refseq:NP_724888.2|refseq:NP_724889.2|refseq:NP_995792.1|flybase:FBgn0004907|dip:DIP-17371N|ensemblmetazoa:FBgn0004907(gene)|ensemblmetazoa:FBtr0088414(transcript)|ensemblmetazoa:FBtr0088415(transcript)|ensemblmetazoa:FBtr0100183(transcript)|ensemblmetazoa:FBtr0332916(transcript)|ensemblmetazoa:FBtr0332917(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045172"(germline ring canal)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0120176"(positive regulation of torso signaling pathway)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-170968|reactome:R-DME-2028269|reactome:R-DME-3769402|reactome:R-DME-390098|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-450385|reactome:R-DME-450513|reactome:R-DME-450604|reactome:R-DME-5625740|reactome:R-DME-5628897|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6804114|reactome:R-DME-75035|reactome:R-DME-9013700|reactome:R-DME-9614399 pubmed:12431373(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Omcx4yx4w1yGPngw1s7ClWPmCZs7227 rogid:G1jZJfZZqZwEu9lekPYYdvZAXO87227 intact-crc:84FB642429EABD26|rigid:bytCko7b5svnl7vkFCkQ6DrGpPM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P29310 uniprotkb:P29310 intact:EBI-198100|intact:EBI-1630797|uniprotkb:A4UZB2|uniprotkb:A4UZB3|uniprotkb:O01665|uniprotkb:Q0E9D5|uniprotkb:Q0E9D6|uniprotkb:Q0E9D7|uniprotkb:Q8IGB9|uniprotkb:Q8MKV5|uniprotkb:Q9V5G6|uniprotkb:C1C593|uniprotkb:C9QP27|ensemblmetazoa:FBpp0087502|ensemblmetazoa:FBpp0087503|ensemblmetazoa:FBpp0099540|ensemblmetazoa:FBpp0305136|ensemblmetazoa:FBpp0305137 intact:EBI-198100|intact:EBI-1630797|uniprotkb:A4UZB2|uniprotkb:A4UZB3|uniprotkb:O01665|uniprotkb:Q0E9D5|uniprotkb:Q0E9D6|uniprotkb:Q0E9D7|uniprotkb:Q8IGB9|uniprotkb:Q8MKV5|uniprotkb:Q9V5G6|uniprotkb:C1C593|uniprotkb:C9QP27|ensemblmetazoa:FBpp0087502|ensemblmetazoa:FBpp0087503|ensemblmetazoa:FBpp0099540|ensemblmetazoa:FBpp0305136|ensemblmetazoa:FBpp0305137 psi-mi:1433z_drome(display_long)|uniprotkb:14-3-3zeta(gene name)|psi-mi:14-3-3zeta(display_short)|uniprotkb:14-3-3EZ(gene name synonym)|uniprotkb:leo(gene name synonym)|uniprotkb:14-3-3(gene name synonym)|uniprotkb:THAP(gene name synonym)|uniprotkb:CG17870(orf name)|uniprotkb:14-3-3-like protein(gene name synonym)|uniprotkb:Protein Leonardo(gene name synonym) psi-mi:1433z_drome(display_long)|uniprotkb:14-3-3zeta(gene name)|psi-mi:14-3-3zeta(display_short)|uniprotkb:14-3-3EZ(gene name synonym)|uniprotkb:leo(gene name synonym)|uniprotkb:14-3-3(gene name synonym)|uniprotkb:THAP(gene name synonym)|uniprotkb:CG17870(orf name)|uniprotkb:14-3-3-like protein(gene name synonym)|uniprotkb:Protein Leonardo(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871070 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001260845.1|refseq:NP_001260846.1|refseq:NP_001014515.1|refseq:NP_001014516.1|refseq:NP_476885.2|refseq:NP_724884.1|refseq:NP_724885.1|refseq:NP_724886.1|refseq:NP_724887.2|refseq:NP_724888.2|refseq:NP_724889.2|refseq:NP_995792.1|flybase:FBgn0004907|dip:DIP-17371N|ensemblmetazoa:FBgn0004907(gene)|ensemblmetazoa:FBtr0088414(transcript)|ensemblmetazoa:FBtr0088415(transcript)|ensemblmetazoa:FBtr0100183(transcript)|ensemblmetazoa:FBtr0332916(transcript)|ensemblmetazoa:FBtr0332917(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045172"(germline ring canal)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0120176"(positive regulation of torso signaling pathway)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-170968|reactome:R-DME-2028269|reactome:R-DME-3769402|reactome:R-DME-390098|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-450385|reactome:R-DME-450513|reactome:R-DME-450604|reactome:R-DME-5625740|reactome:R-DME-5628897|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6804114|reactome:R-DME-75035|reactome:R-DME-9013700|reactome:R-DME-9614399 refseq:NP_001260845.1|refseq:NP_001260846.1|refseq:NP_001014515.1|refseq:NP_001014516.1|refseq:NP_476885.2|refseq:NP_724884.1|refseq:NP_724885.1|refseq:NP_724886.1|refseq:NP_724887.2|refseq:NP_724888.2|refseq:NP_724889.2|refseq:NP_995792.1|flybase:FBgn0004907|dip:DIP-17371N|ensemblmetazoa:FBgn0004907(gene)|ensemblmetazoa:FBtr0088414(transcript)|ensemblmetazoa:FBtr0088415(transcript)|ensemblmetazoa:FBtr0100183(transcript)|ensemblmetazoa:FBtr0332916(transcript)|ensemblmetazoa:FBtr0332917(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045172"(germline ring canal)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0120176"(positive regulation of torso signaling pathway)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-170968|reactome:R-DME-2028269|reactome:R-DME-3769402|reactome:R-DME-390098|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-450385|reactome:R-DME-450513|reactome:R-DME-450604|reactome:R-DME-5625740|reactome:R-DME-5628897|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6804114|reactome:R-DME-75035|reactome:R-DME-9013700|reactome:R-DME-9614399 pubmed:12529354(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:G1jZJfZZqZwEu9lekPYYdvZAXO87227 rogid:G1jZJfZZqZwEu9lekPYYdvZAXO87227 intact-crc:CE7A26479CD8F53F|rigid:a0OxUXY7WR7IztBM9YXC7tZ/dY8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9UAE7 uniprotkb:Q9N9Z7 intact:EBI-867486 intact:EBI-867477|ensemblmetazoa:FBpp0100150 psi-mi:q9uae7_drome(display_long)|uniprotkb:amon(gene name)|psi-mi:amon(display_short)|uniprotkb:PC2(gene name synonym)|uniprotkb:CG6438(orf name) psi-mi:q9n9z7_drome(display_long)|uniprotkb:7B2(gene name)|psi-mi:7B2(display_short)|uniprotkb:N-terminal peptide(gene name synonym)|uniprotkb:Neuroendocrine protein 7B2(gene name synonym)|uniprotkb:CG1168(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871074 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0023179|go:"GO:0002165"(instar larval or pupal development)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008233"(peptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0035180"(larval wandering behavior)|go:"GO:0035187"(hatching behavior)|go:"GO:0043005"(neuron projection)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR032815|interpro:IPR034182|interpro:IPR036852|interpro:IPR038466 flybase:FBgn0041707|ensemblmetazoa:FBgn0041707(gene)|ensemblmetazoa:FBtr0301640(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0030141"(secretory granule)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046883"(regulation of hormone secretion)|interpro:IPR007945(Neuroendocrine 7B2 precursor) pubmed:10749852(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:106oWCK9IBdj1WIhWbx/CPpzAEw7227 rogid:l7lOwIhL0WRGRk7MBHjg/APPPWs7227 intact-crc:8C9614E878CF39D3|rigid:azY7WA7VYj36G/3Q/vB90v8euds false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40427 uniprotkb:P29555 intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515 intact:EBI-201507|uniprotkb:Q5U161|uniprotkb:Q9VER1|ensemblmetazoa:FBpp0082829 psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name) psi-mi:abda_drome(display_long)|uniprotkb:abd-A(gene name)|psi-mi:abd-A(display_short)|uniprotkb:CG10325(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871078 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N refseq:NP_001163632.1|refseq:NP_476693.1|refseq:NP_732176.1|flybase:FBgn0000014|refseq:NP_001247145.1|dip:DIP-17987N|ensemblmetazoa:FBgn0000014(gene)|ensemblmetazoa:FBtr0083388(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007280"(pole cell migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007494"(midgut development)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008354"(germ cell migration)|go:"GO:0008406"(gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0014019"(neuroblast development)|go:"GO:0035053"(dorsal vessel heart proper cell fate commitment)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048636"(positive regulation of muscle organ development)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0048806"(genitalia development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022132 pubmed:7846045(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227 rogid:CUVIdePTLQpatmgnFaiLk4p8+N07227 intact-crc:EB7FD271DE8A1B8F|rigid:XvfDxyMtkygK8xQ9pCe77/kM+9g false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P00522 uniprotkb:Q9Y0S9 intact:EBI-534090|uniprotkb:Q95TV1|uniprotkb:Q9VV86|ensemblmetazoa:FBpp0075116|ensemblmetazoa:FBpp0311523 intact:EBI-167860|ensemblmetazoa:FBpp0082371|ensemblmetazoa:FBpp0111809|ensemblmetazoa:FBpp0308013 psi-mi:abl_drome(display_long)|uniprotkb:Protein abelson(gene name synonym)|uniprotkb:Abl(gene name)|psi-mi:Abl(display_short)|uniprotkb:ABL-1(gene name synonym)|uniprotkb:Dash(gene name synonym)|uniprotkb:CG4032(orf name)|uniprotkb:D-ash(gene name synonym) psi-mi:q9y0s9_drome(display_long)|uniprotkb:Abi(gene name)|psi-mi:Abi(display_short)|uniprotkb:Abi-1(gene name synonym)|uniprotkb:Ablphilin(gene name synonym)|uniprotkb:Dmel\CG9749(gene name synonym)|uniprotkb:abi(gene name synonym)|uniprotkb:dAbi(gene name synonym)|uniprotkb:Dmel_CG9749(orf name)|uniprotkb:CG9749(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871082 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048749"(compound eye development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072499"(photoreceptor cell axon guidance)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016199"(axon midline choice point recognition)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|reactome:R-DME-2029482|reactome:R-DME-428890|reactome:R-DME-525793|reactome:R-DME-5663213|reactome:R-DME-69231|reactome:R-DME-8939236|reactome:R-DME-9013149|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0030424"(axon)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046777"(protein autophosphorylation)|refseq:NP_001287085.1|refseq:NP_524843.2|flybase:FBgn0000017|ensemblmetazoa:FBgn0000017(gene)|ensemblmetazoa:FBtr0075357(transcript)|ensemblmetazoa:FBtr0345369(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007611"(learning or memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008064"(regulation of actin polymerization or depolymerization) refseq:NP_001097785.1|refseq:NP_477263.1|flybase:FBgn0020510|refseq:NP_001262560.1|ensemblmetazoa:FBgn0020510(gene)|ensemblmetazoa:FBtr0082910(transcript)|ensemblmetazoa:FBtr0112896(transcript)|ensemblmetazoa:FBtr0337097(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016203"(muscle attachment)|go:"GO:0016301"(kinase activity)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031209"(SCAR complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0045178"(basal part of cell)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0072499"(photoreceptor cell axon guidance)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|dip:DIP-35544N pubmed:10498863(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:WKRZSDhhHjjnTfp73ErazsbPW9o7227 rogid:yEhDK1eX6QA17tnpEkgXgLnkN2o7227 intact-crc:14ECD6D15667EC9F|rigid:aOFZaQcwdJ8dEs96xdM4YBxhuyc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O44924 uniprotkb:P00522 intact:EBI-74797 intact:EBI-534090|uniprotkb:Q95TV1|uniprotkb:Q9VV86|ensemblmetazoa:FBpp0075116|ensemblmetazoa:FBpp0311523 psi-mi:o44924_drome(display_long)|uniprotkb:robo1(gene name)|psi-mi:robo1(display_short)|uniprotkb:robo(gene name synonym)|uniprotkb:CG13521(orf name) psi-mi:abl_drome(display_long)|uniprotkb:Protein abelson(gene name synonym)|uniprotkb:Abl(gene name)|psi-mi:Abl(display_short)|uniprotkb:ABL-1(gene name synonym)|uniprotkb:Dash(gene name synonym)|uniprotkb:CG4032(orf name)|uniprotkb:D-ash(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871086 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0005631|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0008038"(neuron recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008406"(gonad development)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0070983"(dendrite guidance)|go:"GO:0071666"(Slit-Robo signaling complex)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2VR9|rcsb pdb:2VRA go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048749"(compound eye development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072499"(photoreceptor cell axon guidance)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016199"(axon midline choice point recognition)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|reactome:R-DME-2029482|reactome:R-DME-428890|reactome:R-DME-525793|reactome:R-DME-5663213|reactome:R-DME-69231|reactome:R-DME-8939236|reactome:R-DME-9013149|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0030424"(axon)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046777"(protein autophosphorylation)|refseq:NP_001287085.1|refseq:NP_524843.2|flybase:FBgn0000017|ensemblmetazoa:FBgn0000017(gene)|ensemblmetazoa:FBtr0075357(transcript)|ensemblmetazoa:FBtr0345369(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007611"(learning or memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008064"(regulation of actin polymerization or depolymerization) pubmed:10892742(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:uLUQxfvRN9BQCyxNV6w22/4BtGw7227 rogid:WKRZSDhhHjjnTfp73ErazsbPW9o7227 intact-crc:8F7B0BB3AEBBB8C9|rigid:9dlYKmuunPCs1YdBVDh6ungLmeA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8T4F7 uniprotkb:P00522 intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115 intact:EBI-534090|uniprotkb:Q95TV1|uniprotkb:Q9VV86|ensemblmetazoa:FBpp0075116|ensemblmetazoa:FBpp0311523 psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym) psi-mi:abl_drome(display_long)|uniprotkb:Protein abelson(gene name synonym)|uniprotkb:Abl(gene name)|psi-mi:Abl(display_short)|uniprotkb:ABL-1(gene name synonym)|uniprotkb:Dash(gene name synonym)|uniprotkb:CG4032(orf name)|uniprotkb:D-ash(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871090 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization) go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048749"(compound eye development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072499"(photoreceptor cell axon guidance)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016199"(axon midline choice point recognition)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|reactome:R-DME-2029482|reactome:R-DME-428890|reactome:R-DME-525793|reactome:R-DME-5663213|reactome:R-DME-69231|reactome:R-DME-8939236|reactome:R-DME-9013149|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0030424"(axon)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046777"(protein autophosphorylation)|refseq:NP_001287085.1|refseq:NP_524843.2|flybase:FBgn0000017|ensemblmetazoa:FBgn0000017(gene)|ensemblmetazoa:FBtr0075357(transcript)|ensemblmetazoa:FBtr0345369(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007611"(learning or memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008064"(regulation of actin polymerization or depolymerization) pubmed:7535279(see-also)|pubmed:9418863(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227 rogid:WKRZSDhhHjjnTfp73ErazsbPW9o7227 intact-crc:BD652DB44E1DA910|rigid:76buOTo56l4eEoVVkX3DGrYq7Vo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KN55 uniprotkb:P00522 intact:EBI-867513|ensemblmetazoa:FBpp0099391 intact:EBI-534090|uniprotkb:Q95TV1|uniprotkb:Q9VV86|ensemblmetazoa:FBpp0075116|ensemblmetazoa:FBpp0311523 psi-mi:q7kn55_drome(display_long)|uniprotkb:capt(gene name)|psi-mi:capt(display_short)|uniprotkb:CG33979(orf name) psi-mi:abl_drome(display_long)|uniprotkb:Protein abelson(gene name synonym)|uniprotkb:Abl(gene name)|psi-mi:Abl(display_short)|uniprotkb:ABL-1(gene name synonym)|uniprotkb:Dash(gene name synonym)|uniprotkb:CG4032(orf name)|uniprotkb:D-ash(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871094 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261458|ensemblmetazoa:FBgn0261458(gene)|ensemblmetazoa:FBtr0100023(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0042052"(rhabdomere development)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0072499"(photoreceptor cell axon guidance)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|interpro:IPR003124(Actin-binding WH2) go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048749"(compound eye development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072499"(photoreceptor cell axon guidance)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016199"(axon midline choice point recognition)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|reactome:R-DME-2029482|reactome:R-DME-428890|reactome:R-DME-525793|reactome:R-DME-5663213|reactome:R-DME-69231|reactome:R-DME-8939236|reactome:R-DME-9013149|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0030424"(axon)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046777"(protein autophosphorylation)|refseq:NP_001287085.1|refseq:NP_524843.2|flybase:FBgn0000017|ensemblmetazoa:FBgn0000017(gene)|ensemblmetazoa:FBtr0075357(transcript)|ensemblmetazoa:FBtr0345369(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007611"(learning or memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008064"(regulation of actin polymerization or depolymerization) pubmed:12441051(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:/Hack3xuzikW2Z48QQo+343/oEg7227 rogid:WKRZSDhhHjjnTfp73ErazsbPW9o7227 intact-crc:9941C8F36C4050B7|rigid:GPtmOlqYlhqNRCeXvpX5xPxcj8U false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10084 uniprotkb:P10083 intact:EBI-174136|intact:EBI-1639078|uniprotkb:O76890|uniprotkb:Q4V705|ensemblmetazoa:FBpp0070072 intact:EBI-152748|intact:EBI-1639067|uniprotkb:Q4V702|uniprotkb:Q9W5G4|ensemblmetazoa:FBpp0070071 psi-mi:ast4_drome(display_long)|uniprotkb:sc(gene name)|psi-mi:sc(display_short)|uniprotkb:T4(gene name synonym)|uniprotkb:Protein scute(gene name synonym)|uniprotkb:sis-b(gene name synonym)|uniprotkb:CG3827(orf name) psi-mi:ast5_drome(display_long)|uniprotkb:ac(gene name)|psi-mi:ac(display_short)|uniprotkb:T5(gene name synonym)|uniprotkb:CG3796(orf name)|uniprotkb:Protein achaete(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871098 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476803.1|flybase:FBgn0004170|dip:DIP-325N|ensemblmetazoa:FBgn0004170(gene)|ensemblmetazoa:FBtr0070073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638 refseq:NP_476824.1|flybase:FBgn0000022|ensemblmetazoa:FBgn0000022(gene)|ensemblmetazoa:FBtr0070072(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|dip:DIP-187N pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:WTTmp3SuZ10YiZMKYALr68UiRO07227 rogid:ZQwyQ9i9UZhBZw4+FgnPzCIbuIM7227 intact-crc:64C5747C87995510|rigid:qN1+V0FH+5qG8gSo/zO3tmj/46M false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09774 uniprotkb:P10083 intact:EBI-174224|intact:EBI-1628024|uniprotkb:Q24387|uniprotkb:Q8MRA5|ensemblmetazoa:FBpp0070073 intact:EBI-152748|intact:EBI-1639067|uniprotkb:Q4V702|uniprotkb:Q9W5G4|ensemblmetazoa:FBpp0070071 psi-mi:ast3_drome(display_long)|uniprotkb:"l(1)sc"(gene name)|psi-mi:"l(1)sc"(display_short)|uniprotkb:T3(gene name synonym)|uniprotkb:l'sc(gene name synonym)|uniprotkb:CG3839(orf name)|uniprotkb:Protein lethal of scute(gene name synonym) psi-mi:ast5_drome(display_long)|uniprotkb:ac(gene name)|psi-mi:ac(display_short)|uniprotkb:T5(gene name synonym)|uniprotkb:CG3796(orf name)|uniprotkb:Protein achaete(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871102 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476623.1|flybase:FBgn0002561|ensemblmetazoa:FBgn0002561(gene)|ensemblmetazoa:FBtr0070074(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638 refseq:NP_476824.1|flybase:FBgn0000022|ensemblmetazoa:FBgn0000022(gene)|ensemblmetazoa:FBtr0070072(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|dip:DIP-187N pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6/qKHfmqMOsi8uWoKA4A3IbeOGk7227 rogid:ZQwyQ9i9UZhBZw4+FgnPzCIbuIM7227 intact-crc:FFFAC47E48E66BCE|rigid:r2lit3ujmQI2gZR62ayIc8GwtUI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10083 uniprotkb:P13097 intact:EBI-152748|intact:EBI-1639067|uniprotkb:Q4V702|uniprotkb:Q9W5G4|ensemblmetazoa:FBpp0070071 intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334 psi-mi:ast5_drome(display_long)|uniprotkb:ac(gene name)|psi-mi:ac(display_short)|uniprotkb:T5(gene name synonym)|uniprotkb:CG3796(orf name)|uniprotkb:Protein achaete(gene name synonym) psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476824.1|flybase:FBgn0000022|ensemblmetazoa:FBgn0000022(gene)|ensemblmetazoa:FBtr0070072(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|dip:DIP-187N refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ZQwyQ9i9UZhBZw4+FgnPzCIbuIM7227 rogid:ko+76awzLWRJNBn06B3PQZWBhf47227 intact-crc:CDBE9AB099106440|rigid:lQEnp3iFb6sxR0+SxlPX5YL7ETk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P13096 uniprotkb:P10083 intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352 intact:EBI-152748|intact:EBI-1639067|uniprotkb:Q4V702|uniprotkb:Q9W5G4|ensemblmetazoa:FBpp0070071 psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name) psi-mi:ast5_drome(display_long)|uniprotkb:ac(gene name)|psi-mi:ac(display_short)|uniprotkb:T5(gene name synonym)|uniprotkb:CG3796(orf name)|uniprotkb:Protein achaete(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871110 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 refseq:NP_476824.1|flybase:FBgn0000022|ensemblmetazoa:FBgn0000022(gene)|ensemblmetazoa:FBtr0070072(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|dip:DIP-187N pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227 rogid:ZQwyQ9i9UZhBZw4+FgnPzCIbuIM7227 intact-crc:D9AF9AB08261A42B|rigid:Sl48YAp8FMcdrtS9/jHyTpkmB1Y false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18491 uniprotkb:P10083 intact:EBI-105737|intact:EBI-1639647|uniprotkb:Q9W0N0|intact:EBI-3431186|ensemblmetazoa:FBpp0072477 intact:EBI-152748|intact:EBI-1639067|uniprotkb:Q4V702|uniprotkb:Q9W5G4|ensemblmetazoa:FBpp0070071 psi-mi:emc_drome(display_long)|uniprotkb:emc(gene name)|psi-mi:emc(display_short)|uniprotkb:CG1007(orf name) psi-mi:ast5_drome(display_long)|uniprotkb:ac(gene name)|psi-mi:ac(display_short)|uniprotkb:T5(gene name synonym)|uniprotkb:CG3796(orf name)|uniprotkb:Protein achaete(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871114 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|go:"GO:0046552"(photoreceptor cell fate commitment)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0061525"(hindgut development)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_523876.2|flybase:FBgn0000575|dip:DIP-73N|ensemblmetazoa:FBgn0000575(gene)|ensemblmetazoa:FBtr0072578(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007391"(dorsal closure)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0007530"(sex determination)|go:"GO:0008258"(head involution)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0030154"(cell differentiation) refseq:NP_476824.1|flybase:FBgn0000022|ensemblmetazoa:FBgn0000022(gene)|ensemblmetazoa:FBtr0070072(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|dip:DIP-187N pubmed:7821225(see-also)|pubmed:8497266(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:JfE7tW1Lu4C7KafkWe31A98gZoM7227 rogid:ZQwyQ9i9UZhBZw4+FgnPzCIbuIM7227 intact-crc:48F3821F2443F184|rigid:T1B4N9Qy/A3akFDoxUpZbwh2zZk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P13098 uniprotkb:P10083 intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335 intact:EBI-152748|intact:EBI-1639067|uniprotkb:Q4V702|uniprotkb:Q9W5G4|ensemblmetazoa:FBpp0070071 psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name) psi-mi:ast5_drome(display_long)|uniprotkb:ac(gene name)|psi-mi:ac(display_short)|uniprotkb:T5(gene name synonym)|uniprotkb:CG3796(orf name)|uniprotkb:Protein achaete(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 refseq:NP_476824.1|flybase:FBgn0000022|ensemblmetazoa:FBgn0000022(gene)|ensemblmetazoa:FBtr0070072(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|dip:DIP-187N pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227 rogid:ZQwyQ9i9UZhBZw4+FgnPzCIbuIM7227 intact-crc:01419AB002CB2609|rigid:C9qCNuZP5O6EAZQV26NDr+3PZXk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P11420 uniprotkb:P10083 intact:EBI-151268|intact:EBI-1639097|uniprotkb:Q9VKX3|ensemblmetazoa:FBpp0079598|ensemblmetazoa:FBpp0304504|ensemblmetazoa:FBpp0304505 intact:EBI-152748|intact:EBI-1639067|uniprotkb:Q4V702|uniprotkb:Q9W5G4|ensemblmetazoa:FBpp0070071 psi-mi:da_drome(display_long)|uniprotkb:da(gene name)|psi-mi:da(display_short)|uniprotkb:CG5102(orf name) psi-mi:ast5_drome(display_long)|uniprotkb:ac(gene name)|psi-mi:ac(display_short)|uniprotkb:T5(gene name synonym)|uniprotkb:CG3796(orf name)|uniprotkb:Protein achaete(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007423"(sensory organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030237"(female sex determination)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050821"(protein stabilization)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-525793|reactome:R-DME-8939236|go:"GO:0061525"(hindgut development)|flybase:FBgn0267821|ensemblmetazoa:FBgn0267821(gene)|ensemblmetazoa:FBtr0080008(transcript)|ensemblmetazoa:FBtr0332195(transcript)|ensemblmetazoa:FBtr0332196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_477189.1|refseq:NP_001260340.1|refseq:NP_001260341.1|dip:DIP-50N refseq:NP_476824.1|flybase:FBgn0000022|ensemblmetazoa:FBgn0000022(gene)|ensemblmetazoa:FBtr0070072(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|dip:DIP-187N pubmed:1764999(see-also)|pubmed:7600969(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:EwPK9ObnWH1gzRFPpERKnmw/kDA7227 rogid:ZQwyQ9i9UZhBZw4+FgnPzCIbuIM7227 intact-crc:933A1EDD89CDF57D|rigid:yuKzICS9+Cd0YYLTGWqb5QMNHaM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10083 uniprotkb:P10083 intact:EBI-152748|intact:EBI-1639067|uniprotkb:Q4V702|uniprotkb:Q9W5G4|ensemblmetazoa:FBpp0070071 intact:EBI-152748|intact:EBI-1639067|uniprotkb:Q4V702|uniprotkb:Q9W5G4|ensemblmetazoa:FBpp0070071 psi-mi:ast5_drome(display_long)|uniprotkb:ac(gene name)|psi-mi:ac(display_short)|uniprotkb:T5(gene name synonym)|uniprotkb:CG3796(orf name)|uniprotkb:Protein achaete(gene name synonym) psi-mi:ast5_drome(display_long)|uniprotkb:ac(gene name)|psi-mi:ac(display_short)|uniprotkb:T5(gene name synonym)|uniprotkb:CG3796(orf name)|uniprotkb:Protein achaete(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871126 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476824.1|flybase:FBgn0000022|ensemblmetazoa:FBgn0000022(gene)|ensemblmetazoa:FBtr0070072(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|dip:DIP-187N refseq:NP_476824.1|flybase:FBgn0000022|ensemblmetazoa:FBgn0000022(gene)|ensemblmetazoa:FBtr0070072(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638|dip:DIP-187N pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ZQwyQ9i9UZhBZw4+FgnPzCIbuIM7227 rogid:ZQwyQ9i9UZhBZw4+FgnPzCIbuIM7227 intact-crc:08B2747CC7CC1401|rigid:KYLllUlkrwTo/wQ526/HrMZSJic false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24150 uniprotkb:Q5BI37 intact:EBI-603430 intact:EBI-867522|ensemblmetazoa:FBpp0085204 psi-mi:q24150_drome(display_long)|uniprotkb:Nap1(gene name)|psi-mi:Nap1(display_short)|uniprotkb:CG5330(orf name) psi-mi:q5bi37_drome(display_long)|uniprotkb:Acf(gene name)|psi-mi:Acf(display_short)|uniprotkb:Acf1(gene name synonym)|uniprotkb:CG1966(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871130 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000723"(telomere maintenance)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0035041"(sperm DNA decondensation)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|flybase:FBgn0015268 flybase:FBgn0027620|ensemblmetazoa:FBgn0027620(gene)|ensemblmetazoa:FBtr0085845(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007399"(nervous system development)|go:"GO:0008623"(CHRAC)|go:"GO:0016573"(histone acetylation)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016590"(ACF complex)|go:"GO:0031445"(regulation of heterochromatin assembly)|go:"GO:0031497"(chromatin assembly)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR028941 pubmed:11054407(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NvLzkn4vQ1SBJDrKk24AE4sFmrI7227 rogid:CkOmBiNqqtRFvBHWLHx7fHJEmNE7227 intact-crc:8B66B520D5C9D985|rigid:Je/LtIzl5Z0wsZSeK77vVpSm2i4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24368 uniprotkb:Q5BI37 intact:EBI-367628|uniprotkb:A4UZF0|uniprotkb:Q0E9A4|uniprotkb:Q8SX14|uniprotkb:Q9V6E8|uniprotkb:B5X0J3|ensemblmetazoa:FBpp0086954|ensemblmetazoa:FBpp0086955|ensemblmetazoa:FBpp0086956 intact:EBI-867522|ensemblmetazoa:FBpp0085204 psi-mi:iswi_drome(display_long)|uniprotkb:Iswi(gene name)|psi-mi:Iswi(display_short)|uniprotkb:CG8625(orf name)|uniprotkb:Protein imitation swi(gene name synonym)|uniprotkb:Nucleosome-remodeling factor 140 kDa subunit(gene name synonym)|uniprotkb:CHRAC 140 kDa subunit(gene name synonym) psi-mi:q5bi37_drome(display_long)|uniprotkb:Acf(gene name)|psi-mi:Acf(display_short)|uniprotkb:Acf1(gene name synonym)|uniprotkb:CG1966(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871134 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523719.1|refseq:NP_725203.1|refseq:NP_725204.1|flybase:FBgn0011604|go:"GO:0031213"(RSF complex)|interpro:IPR044754|mint:Q24368|rcsb pdb:1OFC|ensemblmetazoa:FBgn0011604(gene)|go:"GO:0031010"(ISWI-type complex)|ensemblmetazoa:FBtr0087841(transcript)|ensemblmetazoa:FBtr0087842(transcript)|ensemblmetazoa:FBtr0087843(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008623"(CHRAC)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016590"(ACF complex)|go:"GO:0035041"(sperm DNA decondensation)|go:"GO:0035063"(nuclear speck organization)|go:"GO:0035076"(ecdysone receptor-mediated signaling pathway)|go:"GO:0031491"(nucleosome binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|dip:DIP-24067N flybase:FBgn0027620|ensemblmetazoa:FBgn0027620(gene)|ensemblmetazoa:FBtr0085845(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007399"(nervous system development)|go:"GO:0008623"(CHRAC)|go:"GO:0016573"(histone acetylation)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016590"(ACF complex)|go:"GO:0031445"(regulation of heterochromatin assembly)|go:"GO:0031497"(chromatin assembly)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR028941 pubmed:9419341(see-also)|pubmed:10385622(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Y+DR8T/CS52ezjthM6C5qhkyPiw7227 rogid:CkOmBiNqqtRFvBHWLHx7fHJEmNE7227 intact-crc:C77B357948869BD4|rigid:Fm7gkve2p4CxhcagoHH9akov4m4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16241 uniprotkb:P24350 intact:EBI-132677|uniprotkb:Q24460|uniprotkb:Q86P26|uniprotkb:Q9VRY9|ensemblmetazoa:FBpp0076653|ensemblmetazoa:FBpp0311831 intact:EBI-867534|uniprotkb:O77214|uniprotkb:Q26465|uniprotkb:Q59E44|uniprotkb:Q59E45|uniprotkb:Q8IR36|uniprotkb:Q9VXW1|ensemblmetazoa:FBpp0073832 psi-mi:cf1a_drome(display_long)|uniprotkb:CG10037(orf name)|uniprotkb:vvl(gene name)|psi-mi:vvl(display_short)|uniprotkb:Cf1a(gene name synonym)|uniprotkb:Chorion factor 1A(gene name synonym)|uniprotkb:Ventral veins lacking protein(gene name synonym)|uniprotkb:Protein drifter(gene name synonym) psi-mi:ipou_drome(display_long)|uniprotkb:Abnormal chemosensory jump 6 protein(gene name synonym)|uniprotkb:acj6(gene name)|psi-mi:acj6(display_short)|uniprotkb:Ipou(gene name synonym)|uniprotkb:CG9151(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871138 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523948.1|flybase:FBgn0086680|refseq:NP_001286957.1|ensemblmetazoa:FBgn0086680(gene)|ensemblmetazoa:FBtr0076944(transcript)|ensemblmetazoa:FBtr0345911(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002807"(positive regulation of antimicrobial peptide biosynthetic process)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0035284"(brain segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR016362(Transcription factor, homeobox/POU)|interpro:IPR017970|dip:DIP-17200N refseq:NP_001014743.1|refseq:NP_001014744.1|refseq:NP_524876.1|refseq:NP_727845.1|flybase:FBgn0000028|ensemblmetazoa:FBgn0000028(gene)|ensemblmetazoa:FBtr0074015(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007411"(axon guidance)|go:"GO:0007636"(chemosensory jump behavior)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050911"(detection of chemical stimulus involved in sensory perception of smell)|go:"GO:0070983"(dendrite guidance)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|reactome:R-DME-6804759 pubmed:1346754(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:5KOEjYBWVSLPmVYoSIRHX3/NbcU7227 rogid:SQ2SIqtFaZjrKc3AOYh5t2ffcaw7227 intact-crc:4BBB956B78A136E7|rigid:0aLt3sLWLnsy/3eBG9lEDYcYn+I false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9NCC3 uniprotkb:Q8MRP0 intact:EBI-163600|uniprotkb:Q9VT36|ensemblmetazoa:FBpp0076142 intact:EBI-867563|ensemblmetazoa:FBpp0073067 psi-mi:q9ncc3_drome(display_long)|uniprotkb:SH3PX1(gene name)|psi-mi:SH3PX1(display_short)|uniprotkb:DSH3PX1(gene name synonym)|uniprotkb:DSH3PX(gene name synonym)|uniprotkb:DmSNX18(gene name synonym)|uniprotkb:Dmel\CG6757(gene name synonym)|uniprotkb:dSH3PX1(gene name synonym)|uniprotkb:p63(gene name synonym)|uniprotkb:sh3px1(gene name synonym)|uniprotkb:Dmel_CG6757(orf name)|uniprotkb:CG6757(orf name)|uniprotkb:Sh3px1(gene name synonym) psi-mi:q8mrp0_drome(display_long)|uniprotkb:Ack(gene name)|psi-mi:Ack(display_short)|uniprotkb:CG14992(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871142 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648348.1|flybase:FBgn0040475|ensemblmetazoa:FBgn0040475(gene)|ensemblmetazoa:FBtr0076413(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0015031"(protein transport)|go:"GO:0019900"(kinase binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1990709"(presynaptic active zone organization)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR036028|interpro:IPR036871|reactome:R-DME-432722|reactome:R-DME-8856828 flybase:FBgn0028484|ensemblmetazoa:FBgn0028484(gene)|ensemblmetazoa:FBtr0073211(transcript)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007286"(spermatid development)|go:"GO:0007391"(dorsal closure)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0071944"(cell periphery)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote) pubmed:11773052(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:sGeWtqBEWF+Y5aaq9lX9EoKO5aE7227 rogid:6j/9/bF/WSSstZzXR4IIGcVE5AU7227 intact-crc:306ABFC08E2CFCB8|rigid:nXsVXoYW8pVou8nNae3TB2Sk6M4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VFM9 uniprotkb:P10987 intact:EBI-140922|ensemblmetazoa:FBpp0082352 intact:EBI-130188|intact:EBI-1630170|uniprotkb:Q24227|uniprotkb:Q6YN46|uniprotkb:Q9U5X7|uniprotkb:Q9W460|uniprotkb:A4V404|ensemblmetazoa:FBpp0070787|ensemblmetazoa:FBpp0070788|ensemblmetazoa:FBpp0100124|ensemblmetazoa:FBpp0100125|ensemblmetazoa:FBpp0311818 psi-mi:twf_drome(display_long)|uniprotkb:twf(gene name)|psi-mi:twf(display_short)|uniprotkb:CG3172(orf name) psi-mi:act1_drome(display_long)|uniprotkb:Act5C(gene name)|psi-mi:Act5C(display_short)|uniprotkb:CG4027(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650338.1|flybase:FBgn0038206|ensemblmetazoa:FBgn0038206(gene)|ensemblmetazoa:FBtr0082891(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016319"(mushroom body development)|go:"GO:0030016"(myofibril)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0098793"(presynapse)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|reactome:R-DME-9013418 refseq:NP_001014725.1|refseq:NP_001014726.1|refseq:NP_511052.1|refseq:NP_727048.1|flybase:FBgn0000042|refseq:NP_001284915.1|ensemblmetazoa:FBgn0000042(gene)|ensemblmetazoa:FBtr0070822(transcript)|ensemblmetazoa:FBtr0070823(transcript)|ensemblmetazoa:FBtr0100663(transcript)|ensemblmetazoa:FBtr0345894(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007291"(sperm individualization)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035060"(brahma complex)|go:"GO:0035148"(tube formation)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P10987|ensemblmetazoa:FBtr0100662(transcript)|rcsb pdb:1N58|rcsb pdb:2HF3|rcsb pdb:2HF4|rcsb pdb:3EKS|rcsb pdb:3EKU|rcsb pdb:3EL2|rcsb pdb:3MMV|rcsb pdb:3MN6|rcsb pdb:3MN7|rcsb pdb:3MN9|rcsb pdb:4JHD|rcsb pdb:4M63|rcsb pdb:4RWT|rcsb pdb:5WFN|reactome:R-DME-114608|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-3928665|reactome:R-DME-4420097|reactome:R-DME-446353|reactome:R-DME-5663213|reactome:R-DME-5674135|reactome:R-DME-5689603|reactome:R-DME-5696394|reactome:R-DME-8856828|reactome:R-DME-8980692|reactome:R-DME-9013418|reactome:R-DME-9035034|dip:DIP-18961N pubmed:11724820(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:PINHH3dlL9aO44Gny4NAq0ZvLFE7227 rogid:dG1kWhx07XacprdgqtaV16sYdXc7227 intact-crc:D196700DC347E02C|rigid:wXClW+sF2BXNmX9y8go5UAwBI28 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9U1K1 uniprotkb:P10987 intact:EBI-91672|intact:EBI-867570|intact:EBI-499570|uniprotkb:Q9VIN3|uniprotkb:Q9VIN4|uniprotkb:Q5U0Z8|uniprotkb:Q8INV3|uniprotkb:Q8INV4|uniprotkb:Q8INV5|uniprotkb:Q8SXP3|uniprotkb:Q8T8P8|uniprotkb:Q9U4F0|uniprotkb:Q9U4F1|ensemblmetazoa:FBpp0080884 intact:EBI-130188|intact:EBI-1630170|uniprotkb:Q24227|uniprotkb:Q6YN46|uniprotkb:Q9U5X7|uniprotkb:Q9W460|uniprotkb:A4V404|ensemblmetazoa:FBpp0070787|ensemblmetazoa:FBpp0070788|ensemblmetazoa:FBpp0100124|ensemblmetazoa:FBpp0100125|ensemblmetazoa:FBpp0311818 psi-mi:spir_drome(display_long)|uniprotkb:spir(gene name)|psi-mi:spir(display_short)|uniprotkb:p150-Spir(gene name synonym)|uniprotkb:CG10076(orf name) psi-mi:act1_drome(display_long)|uniprotkb:Act5C(gene name)|psi-mi:Act5C(display_short)|uniprotkb:CG4027(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001286100.1|refseq:NP_524854.2|refseq:NP_724254.1|refseq:NP_724255.1|refseq:NP_724256.2|flybase:FBgn0003475|ensemblmetazoa:FBgn0003475(gene)|ensemblmetazoa:FBtr0081352(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046907"(intracellular transport)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0048477"(oogenesis)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0007316"(pole plasm RNA localization)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051639"(actin filament network formation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011019(KIND)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030029"(actin filament-based process)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0030036"(actin cytoskeleton organization)|interpro:IPR029901|rcsb pdb:3MMV|rcsb pdb:3MN5|rcsb pdb:3MN6|rcsb pdb:3MN7|rcsb pdb:3MN9|rcsb pdb:3UE5|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030717"(oocyte karyosome formation)|rcsb pdb:4EFH|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045010"(actin nucleation)|refseq:NP_001246102.1|dip:DIP-17301N refseq:NP_001014725.1|refseq:NP_001014726.1|refseq:NP_511052.1|refseq:NP_727048.1|flybase:FBgn0000042|refseq:NP_001284915.1|ensemblmetazoa:FBgn0000042(gene)|ensemblmetazoa:FBtr0070822(transcript)|ensemblmetazoa:FBtr0070823(transcript)|ensemblmetazoa:FBtr0100663(transcript)|ensemblmetazoa:FBtr0345894(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007291"(sperm individualization)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035060"(brahma complex)|go:"GO:0035148"(tube formation)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P10987|ensemblmetazoa:FBtr0100662(transcript)|rcsb pdb:1N58|rcsb pdb:2HF3|rcsb pdb:2HF4|rcsb pdb:3EKS|rcsb pdb:3EKU|rcsb pdb:3EL2|rcsb pdb:3MMV|rcsb pdb:3MN6|rcsb pdb:3MN7|rcsb pdb:3MN9|rcsb pdb:4JHD|rcsb pdb:4M63|rcsb pdb:4RWT|rcsb pdb:5WFN|reactome:R-DME-114608|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-3928665|reactome:R-DME-4420097|reactome:R-DME-446353|reactome:R-DME-5663213|reactome:R-DME-5674135|reactome:R-DME-5689603|reactome:R-DME-5696394|reactome:R-DME-8856828|reactome:R-DME-8980692|reactome:R-DME-9013418|reactome:R-DME-9035034|dip:DIP-18961N pubmed:10556052(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:d5/uax72i+0dvjWvfORgiCSMjwQ7227 rogid:dG1kWhx07XacprdgqtaV16sYdXc7227 intact-crc:832570E62B95ECE1|rigid:2F1xFhUO63CEr9CBF+dPLNX5Lvs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24524 uniprotkb:P10987 intact:EBI-138461|uniprotkb:Q9W3L8|ensemblmetazoa:FBpp0071057|ensemblmetazoa:FBpp0071058|ensemblmetazoa:FBpp0290891|ensemblmetazoa:FBpp0290893 intact:EBI-130188|intact:EBI-1630170|uniprotkb:Q24227|uniprotkb:Q6YN46|uniprotkb:Q9U5X7|uniprotkb:Q9W460|uniprotkb:A4V404|ensemblmetazoa:FBpp0070787|ensemblmetazoa:FBpp0070788|ensemblmetazoa:FBpp0100124|ensemblmetazoa:FBpp0100125|ensemblmetazoa:FBpp0311818 psi-mi:sing_drome(display_long)|uniprotkb:sn(gene name)|psi-mi:sn(display_short)|uniprotkb:CG1536(orf name) psi-mi:act1_drome(display_long)|uniprotkb:Act5C(gene name)|psi-mi:Act5C(display_short)|uniprotkb:CG4027(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0003447(gene)|ensemblmetazoa:FBtr0071101(transcript)|ensemblmetazoa:FBtr0071102(transcript)|ensemblmetazoa:FBtr0301677(transcript)|ensemblmetazoa:FBtr0301679(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0030034"(microvillar actin bundle assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035099"(hemocyte migration)|refseq:NP_001162697.1|refseq:NP_511076.3|refseq:NP_727226.1|refseq:NP_727227.1|flybase:FBgn0003447|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0042060"(wound healing)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048477"(oogenesis)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR008999(Actin_cross-linking)|interpro:IPR010431(Fascin)|interpro:IPR022768|interpro:IPR024703|interpro:IPR030146 refseq:NP_001014725.1|refseq:NP_001014726.1|refseq:NP_511052.1|refseq:NP_727048.1|flybase:FBgn0000042|refseq:NP_001284915.1|ensemblmetazoa:FBgn0000042(gene)|ensemblmetazoa:FBtr0070822(transcript)|ensemblmetazoa:FBtr0070823(transcript)|ensemblmetazoa:FBtr0100663(transcript)|ensemblmetazoa:FBtr0345894(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007291"(sperm individualization)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035060"(brahma complex)|go:"GO:0035148"(tube formation)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P10987|ensemblmetazoa:FBtr0100662(transcript)|rcsb pdb:1N58|rcsb pdb:2HF3|rcsb pdb:2HF4|rcsb pdb:3EKS|rcsb pdb:3EKU|rcsb pdb:3EL2|rcsb pdb:3MMV|rcsb pdb:3MN6|rcsb pdb:3MN7|rcsb pdb:3MN9|rcsb pdb:4JHD|rcsb pdb:4M63|rcsb pdb:4RWT|rcsb pdb:5WFN|reactome:R-DME-114608|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-3928665|reactome:R-DME-4420097|reactome:R-DME-446353|reactome:R-DME-5663213|reactome:R-DME-5674135|reactome:R-DME-5689603|reactome:R-DME-5696394|reactome:R-DME-8856828|reactome:R-DME-8980692|reactome:R-DME-9013418|reactome:R-DME-9035034|dip:DIP-18961N pubmed:8163553(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:daen4WuxCroMEUGJRCB4lam0XYI7227 rogid:dG1kWhx07XacprdgqtaV16sYdXc7227 intact-crc:31A583B7E733D5F9|rigid:SgUm82q9nuaXPn6/qjeiISszfSM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O77291 uniprotkb:P10987 intact:EBI-347043|uniprotkb:O77292 intact:EBI-130188|intact:EBI-1630170|uniprotkb:Q24227|uniprotkb:Q6YN46|uniprotkb:Q9U5X7|uniprotkb:Q9W460|uniprotkb:A4V404|ensemblmetazoa:FBpp0070787|ensemblmetazoa:FBpp0070788|ensemblmetazoa:FBpp0100124|ensemblmetazoa:FBpp0100125|ensemblmetazoa:FBpp0311818 psi-mi:o77291_drome(display_long)|uniprotkb:shot(gene name)|psi-mi:shot(display_short)|uniprotkb:kak(gene name synonym)|uniprotkb:CG18076(orf name) psi-mi:act1_drome(display_long)|uniprotkb:Act5C(gene name)|psi-mi:Act5C(display_short)|uniprotkb:CG4027(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871158 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0013733|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005912"(adherens junction)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016203"(muscle attachment)|go:"GO:0016319"(mushroom body development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030716"(oocyte fate determination)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045169"(fusome)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051491"(positive regulation of filopodium assembly)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR018159|interpro:IPR035915|interpro:IPR036028|interpro:IPR036872|interpro:IPR041615|interpro:IPR043197 refseq:NP_001014725.1|refseq:NP_001014726.1|refseq:NP_511052.1|refseq:NP_727048.1|flybase:FBgn0000042|refseq:NP_001284915.1|ensemblmetazoa:FBgn0000042(gene)|ensemblmetazoa:FBtr0070822(transcript)|ensemblmetazoa:FBtr0070823(transcript)|ensemblmetazoa:FBtr0100663(transcript)|ensemblmetazoa:FBtr0345894(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007291"(sperm individualization)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035060"(brahma complex)|go:"GO:0035148"(tube formation)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P10987|ensemblmetazoa:FBtr0100662(transcript)|rcsb pdb:1N58|rcsb pdb:2HF3|rcsb pdb:2HF4|rcsb pdb:3EKS|rcsb pdb:3EKU|rcsb pdb:3EL2|rcsb pdb:3MMV|rcsb pdb:3MN6|rcsb pdb:3MN7|rcsb pdb:3MN9|rcsb pdb:4JHD|rcsb pdb:4M63|rcsb pdb:4RWT|rcsb pdb:5WFN|reactome:R-DME-114608|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-3928665|reactome:R-DME-4420097|reactome:R-DME-446353|reactome:R-DME-5663213|reactome:R-DME-5674135|reactome:R-DME-5689603|reactome:R-DME-5696394|reactome:R-DME-8856828|reactome:R-DME-8980692|reactome:R-DME-9013418|reactome:R-DME-9035034|dip:DIP-18961N pubmed:10648715(see-also)|pubmed:11880359(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Bfck8BafKyn0JxkdHFtRCX17hhI7227 rogid:dG1kWhx07XacprdgqtaV16sYdXc7227 intact-crc:EB263C4F0EA9E3AE|rigid:vLC3KY7raMJagEHj2oSY88SMuvk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q23989 uniprotkb:P10987 intact:EBI-144092|intact:EBI-500823|uniprotkb:Q9VJC9|uniprotkb:Q540V4|uniprotkb:Q8INY7|ensemblmetazoa:FBpp0080550 intact:EBI-130188|intact:EBI-1630170|uniprotkb:Q24227|uniprotkb:Q6YN46|uniprotkb:Q9U5X7|uniprotkb:Q9W460|uniprotkb:A4V404|ensemblmetazoa:FBpp0070787|ensemblmetazoa:FBpp0070788|ensemblmetazoa:FBpp0100124|ensemblmetazoa:FBpp0100125|ensemblmetazoa:FBpp0311818 psi-mi:quai_drome(display_long)|uniprotkb:qua(gene name)|psi-mi:qua(display_short)|uniprotkb:CG6433(orf name) psi-mi:act1_drome(display_long)|uniprotkb:Act5C(gene name)|psi-mi:Act5C(display_short)|uniprotkb:CG4027(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871162 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_724060.1|refseq:NP_724061.1|flybase:FBgn0003187|ensemblmetazoa:FBgn0003187(gene)|ensemblmetazoa:FBtr0080997(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR029006|interpro:IPR030016|interpro:IPR036180|interpro:IPR036886|go:"GO:0035317"(imaginal disc-derived wing hair organization) refseq:NP_001014725.1|refseq:NP_001014726.1|refseq:NP_511052.1|refseq:NP_727048.1|flybase:FBgn0000042|refseq:NP_001284915.1|ensemblmetazoa:FBgn0000042(gene)|ensemblmetazoa:FBtr0070822(transcript)|ensemblmetazoa:FBtr0070823(transcript)|ensemblmetazoa:FBtr0100663(transcript)|ensemblmetazoa:FBtr0345894(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007291"(sperm individualization)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035060"(brahma complex)|go:"GO:0035148"(tube formation)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P10987|ensemblmetazoa:FBtr0100662(transcript)|rcsb pdb:1N58|rcsb pdb:2HF3|rcsb pdb:2HF4|rcsb pdb:3EKS|rcsb pdb:3EKU|rcsb pdb:3EL2|rcsb pdb:3MMV|rcsb pdb:3MN6|rcsb pdb:3MN7|rcsb pdb:3MN9|rcsb pdb:4JHD|rcsb pdb:4M63|rcsb pdb:4RWT|rcsb pdb:5WFN|reactome:R-DME-114608|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-3928665|reactome:R-DME-4420097|reactome:R-DME-446353|reactome:R-DME-5663213|reactome:R-DME-5674135|reactome:R-DME-5689603|reactome:R-DME-5696394|reactome:R-DME-8856828|reactome:R-DME-8980692|reactome:R-DME-9013418|reactome:R-DME-9035034|dip:DIP-18961N pubmed:8044841(see-also)|pubmed:10572041(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:qbnEw3sUjt6+ume5W2mm0xlfEQQ7227 rogid:dG1kWhx07XacprdgqtaV16sYdXc7227 intact-crc:7632B3A73DE6CCEC|rigid:ozMThOMNL2yr61EMH+7FmeEFgfc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24339 uniprotkb:P10987 intact:EBI-867580 intact:EBI-130188|intact:EBI-1630170|uniprotkb:Q24227|uniprotkb:Q6YN46|uniprotkb:Q9U5X7|uniprotkb:Q9W460|uniprotkb:A4V404|ensemblmetazoa:FBpp0070787|ensemblmetazoa:FBpp0070788|ensemblmetazoa:FBpp0100124|ensemblmetazoa:FBpp0100125|ensemblmetazoa:FBpp0311818 psi-mi:q24339_drome(display_long)|uniprotkb:f(gene name)|psi-mi:f(display_short)|uniprotkb:forked(gene name synonym)|uniprotkb:CG42864(orf name) psi-mi:act1_drome(display_long)|uniprotkb:Act5C(gene name)|psi-mi:Act5C(display_short)|uniprotkb:CG4027(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871166 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0262111|go:"GO:0005737"(cytoplasm)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 refseq:NP_001014725.1|refseq:NP_001014726.1|refseq:NP_511052.1|refseq:NP_727048.1|flybase:FBgn0000042|refseq:NP_001284915.1|ensemblmetazoa:FBgn0000042(gene)|ensemblmetazoa:FBtr0070822(transcript)|ensemblmetazoa:FBtr0070823(transcript)|ensemblmetazoa:FBtr0100663(transcript)|ensemblmetazoa:FBtr0345894(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007291"(sperm individualization)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035060"(brahma complex)|go:"GO:0035148"(tube formation)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P10987|ensemblmetazoa:FBtr0100662(transcript)|rcsb pdb:1N58|rcsb pdb:2HF3|rcsb pdb:2HF4|rcsb pdb:3EKS|rcsb pdb:3EKU|rcsb pdb:3EL2|rcsb pdb:3MMV|rcsb pdb:3MN6|rcsb pdb:3MN7|rcsb pdb:3MN9|rcsb pdb:4JHD|rcsb pdb:4M63|rcsb pdb:4RWT|rcsb pdb:5WFN|reactome:R-DME-114608|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-3928665|reactome:R-DME-4420097|reactome:R-DME-446353|reactome:R-DME-5663213|reactome:R-DME-5674135|reactome:R-DME-5689603|reactome:R-DME-5696394|reactome:R-DME-8856828|reactome:R-DME-8980692|reactome:R-DME-9013418|reactome:R-DME-9035034|dip:DIP-18961N pubmed:9763425(see-also)|pubmed:10629220(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+SpWfRcCI4yklILCAoMZ/vHr2VA7227 rogid:dG1kWhx07XacprdgqtaV16sYdXc7227 intact-crc:59C30AD14A103D82|rigid:p3I9nQTqElOqGUqkSJ7NhDUHUhQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O97428 uniprotkb:P10987 intact:EBI-158242|ensemblmetazoa:FBpp0070607|ensemblmetazoa:FBpp0070609|ensemblmetazoa:FBpp0298035|ensemblmetazoa:FBpp0310070|intact:EBI-1630485 intact:EBI-130188|intact:EBI-1630170|uniprotkb:Q24227|uniprotkb:Q6YN46|uniprotkb:Q9U5X7|uniprotkb:Q9W460|uniprotkb:A4V404|ensemblmetazoa:FBpp0070787|ensemblmetazoa:FBpp0070788|ensemblmetazoa:FBpp0100124|ensemblmetazoa:FBpp0100125|ensemblmetazoa:FBpp0311818 psi-mi:o97428_drome(display_long)|uniprotkb:cib(gene name)|psi-mi:cib(display_short)|uniprotkb:"EG:EG0007.11"(gene name synonym)|uniprotkb:Dmel_CG4944(orf name)|uniprotkb:CG4944(orf name)|uniprotkb:Dmel\CG4944(gene name synonym)|uniprotkb:EG0007-11(gene name synonym) psi-mi:act1_drome(display_long)|uniprotkb:Act5C(gene name)|psi-mi:Act5C(display_short)|uniprotkb:CG4027(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871170 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0026084(gene)|ensemblmetazoa:FBtr0070639(transcript)|ensemblmetazoa:FBtr0070641(transcript)|ensemblmetazoa:FBtr0307206(transcript)|ensemblmetazoa:FBtr0343425(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007420"(brain development)|go:"GO:0035193"(larval central nervous system remodeling)|interpro:IPR001152(Thymosin beta-4)|interpro:IPR038386|rcsb pdb:1SQK|rcsb pdb:3SJH|rcsb pdb:3U8X|rcsb pdb:3U9D|rcsb pdb:3U9Z|refseq:NP_525065.1|refseq:NP_726908.1|flybase:FBgn0026084|refseq:NP_001284852.1|refseq:NP_001245516.1 refseq:NP_001014725.1|refseq:NP_001014726.1|refseq:NP_511052.1|refseq:NP_727048.1|flybase:FBgn0000042|refseq:NP_001284915.1|ensemblmetazoa:FBgn0000042(gene)|ensemblmetazoa:FBtr0070822(transcript)|ensemblmetazoa:FBtr0070823(transcript)|ensemblmetazoa:FBtr0100663(transcript)|ensemblmetazoa:FBtr0345894(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007291"(sperm individualization)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035060"(brahma complex)|go:"GO:0035148"(tube formation)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P10987|ensemblmetazoa:FBtr0100662(transcript)|rcsb pdb:1N58|rcsb pdb:2HF3|rcsb pdb:2HF4|rcsb pdb:3EKS|rcsb pdb:3EKU|rcsb pdb:3EL2|rcsb pdb:3MMV|rcsb pdb:3MN6|rcsb pdb:3MN7|rcsb pdb:3MN9|rcsb pdb:4JHD|rcsb pdb:4M63|rcsb pdb:4RWT|rcsb pdb:5WFN|reactome:R-DME-114608|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-3928665|reactome:R-DME-4420097|reactome:R-DME-446353|reactome:R-DME-5663213|reactome:R-DME-5674135|reactome:R-DME-5689603|reactome:R-DME-5696394|reactome:R-DME-8856828|reactome:R-DME-8980692|reactome:R-DME-9013418|reactome:R-DME-9035034|dip:DIP-18961N pubmed:11030623(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:kBK00SjDRgmS1CVXE23Im5iS7EA7227 rogid:dG1kWhx07XacprdgqtaV16sYdXc7227 intact-crc:B1A89BC2C2818945|rigid:Tw6eywaJSTKgdeo+7e0NnU3g39Q false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KN55 uniprotkb:P10987 intact:EBI-867513|ensemblmetazoa:FBpp0099391 intact:EBI-130188|intact:EBI-1630170|uniprotkb:Q24227|uniprotkb:Q6YN46|uniprotkb:Q9U5X7|uniprotkb:Q9W460|uniprotkb:A4V404|ensemblmetazoa:FBpp0070787|ensemblmetazoa:FBpp0070788|ensemblmetazoa:FBpp0100124|ensemblmetazoa:FBpp0100125|ensemblmetazoa:FBpp0311818 psi-mi:q7kn55_drome(display_long)|uniprotkb:capt(gene name)|psi-mi:capt(display_short)|uniprotkb:CG33979(orf name) psi-mi:act1_drome(display_long)|uniprotkb:Act5C(gene name)|psi-mi:Act5C(display_short)|uniprotkb:CG4027(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871174 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261458|ensemblmetazoa:FBgn0261458(gene)|ensemblmetazoa:FBtr0100023(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0042052"(rhabdomere development)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0072499"(photoreceptor cell axon guidance)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR028417|interpro:IPR028419|interpro:IPR036222|interpro:IPR036223|interpro:IPR003124(Actin-binding WH2) refseq:NP_001014725.1|refseq:NP_001014726.1|refseq:NP_511052.1|refseq:NP_727048.1|flybase:FBgn0000042|refseq:NP_001284915.1|ensemblmetazoa:FBgn0000042(gene)|ensemblmetazoa:FBtr0070822(transcript)|ensemblmetazoa:FBtr0070823(transcript)|ensemblmetazoa:FBtr0100663(transcript)|ensemblmetazoa:FBtr0345894(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007291"(sperm individualization)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035060"(brahma complex)|go:"GO:0035148"(tube formation)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P10987|ensemblmetazoa:FBtr0100662(transcript)|rcsb pdb:1N58|rcsb pdb:2HF3|rcsb pdb:2HF4|rcsb pdb:3EKS|rcsb pdb:3EKU|rcsb pdb:3EL2|rcsb pdb:3MMV|rcsb pdb:3MN6|rcsb pdb:3MN7|rcsb pdb:3MN9|rcsb pdb:4JHD|rcsb pdb:4M63|rcsb pdb:4RWT|rcsb pdb:5WFN|reactome:R-DME-114608|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-3928665|reactome:R-DME-4420097|reactome:R-DME-446353|reactome:R-DME-5663213|reactome:R-DME-5674135|reactome:R-DME-5689603|reactome:R-DME-5696394|reactome:R-DME-8856828|reactome:R-DME-8980692|reactome:R-DME-9013418|reactome:R-DME-9035034|dip:DIP-18961N pubmed:10985383(see-also)|pubmed:10847682(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:/Hack3xuzikW2Z48QQo+343/oEg7227 rogid:dG1kWhx07XacprdgqtaV16sYdXc7227 intact-crc:F4074DE50750DA53|rigid:CErQbYWwaENo4ABFoTyxV10IZAE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9I7U4 uniprotkb:P83967 intact:EBI-867591|uniprotkb:O76275|uniprotkb:O76276|uniprotkb:O76277|uniprotkb:O76278|uniprotkb:O96767|uniprotkb:O96768|uniprotkb:Q7KA82|uniprotkb:Q7KAJ1|uniprotkb:Q7KPQ8|uniprotkb:Q7RTL4|uniprotkb:Q8T3N3|uniprotkb:Q9N2P7|uniprotkb:Q9N680|uniprotkb:Q9N9Y5|uniprotkb:Q9N9Y6|uniprotkb:Q9N9Y7|uniprotkb:Q9NFS3|uniprotkb:Q9NJP4|uniprotkb:Q9NL88|uniprotkb:Q9UB79|uniprotkb:Q9W055|uniprotkb:Q9XZT9|ensemblmetazoa:FBpp0072727|ensemblmetazoa:FBpp0304925 intact:EBI-184828|uniprotkb:P02575|uniprotkb:P45893|uniprotkb:Q9VF62|ensemblmetazoa:FBpp0082597 psi-mi:titin_drome(display_long)|uniprotkb:D-Titin(gene name synonym)|uniprotkb:Kettin(gene name synonym)|uniprotkb:sls(gene name)|psi-mi:sls(display_short)|uniprotkb:titin(gene name synonym)|uniprotkb:CG1915(orf name) psi-mi:act6_drome(display_long)|uniprotkb:Act88F(gene name)|psi-mi:Act88F(display_short)|uniprotkb:CG5178(orf name)|uniprotkb:Actin-88F(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871178 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524676.2|flybase:FBgn0086906|ensemblmetazoa:FBgn0086906(gene)|ensemblmetazoa:FBtr0072848(transcript)|ensemblmetazoa:FBtr0332679(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003779"(actin binding)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007498"(mesoderm development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016203"(muscle attachment)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0031674"(I band)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0040011"(locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051301"(cell division)|interpro:IPR001452(Src homology-3)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010939(Protein of unknown function DUF1136)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|reactome:R-DME-5658623 refseq:NP_524367.1|flybase:FBgn0000047|ensemblmetazoa:FBgn0000047(gene)|ensemblmetazoa:FBtr0083143(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0071689"(muscle thin filament assembly)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-DME-114608|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-3928665|reactome:R-DME-4420097|reactome:R-DME-446353|reactome:R-DME-5663213|reactome:R-DME-5674135|reactome:R-DME-5689603|reactome:R-DME-5696394|reactome:R-DME-8856828|reactome:R-DME-8980692|reactome:R-DME-9035034 pubmed:2714648(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KudT+8stWca6bWBIOIHz4zh5mqY7227 rogid:PCrrPzr94emHHh1y2mkp7V8yl9c7227 intact-crc:89863A95D0294B6E|rigid:RzuQOe+r7PeRBDxuk0MCqcJJ8gQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P05661 uniprotkb:P83967 intact:EBI-195031|uniprotkb:O18392|uniprotkb:O18393|uniprotkb:Q24412|uniprotkb:Q7JN62|uniprotkb:Q7JN63|uniprotkb:Q7JQ08|uniprotkb:Q7JQ09|uniprotkb:Q7M4K4|uniprotkb:Q8INZ9|uniprotkb:Q8IP00|uniprotkb:Q8IP01|uniprotkb:Q8IP02|uniprotkb:Q8IP03|uniprotkb:Q8IP04|uniprotkb:Q8IP05|uniprotkb:Q8IP06|uniprotkb:Q8IP07|uniprotkb:Q8IP08|uniprotkb:Q8IP09|uniprotkb:Q8IP10|uniprotkb:Q9TY21|uniprotkb:Q9TY22|uniprotkb:Q9TYD7|uniprotkb:Q9VJI3 intact:EBI-184828|uniprotkb:P02575|uniprotkb:P45893|uniprotkb:Q9VF62|ensemblmetazoa:FBpp0082597 psi-mi:mysa_drome(display_long)|uniprotkb:Mhc(gene name)|psi-mi:Mhc(display_short)|uniprotkb:CG17927(orf name) psi-mi:act6_drome(display_long)|uniprotkb:Act88F(gene name)|psi-mi:Act88F(display_short)|uniprotkb:CG5178(orf name)|uniprotkb:Actin-88F(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871182 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162991.1|refseq:NP_523587.4|refseq:NP_723999.1|refseq:NP_724000.1|refseq:NP_724001.1|refseq:NP_724003.1|refseq:NP_724004.1|refseq:NP_724005.1|refseq:NP_724006.1|refseq:NP_724007.1|refseq:NP_724008.1|refseq:NP_724009.1|refseq:NP_724010.1|refseq:NP_724002.2|flybase:FBgn0264695|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007517"(muscle organ development)|go:"GO:0007527"(adult somatic muscle development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0030017"(sarcomere)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031033"(myosin filament organization)|go:"GO:0031672"(A band)|go:"GO:0040011"(locomotion)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060361"(flight)|go:"GO:0071689"(muscle thin filament assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P05661|rcsb pdb:5W1A refseq:NP_524367.1|flybase:FBgn0000047|ensemblmetazoa:FBgn0000047(gene)|ensemblmetazoa:FBtr0083143(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0071689"(muscle thin filament assembly)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-DME-114608|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-3928665|reactome:R-DME-4420097|reactome:R-DME-446353|reactome:R-DME-5663213|reactome:R-DME-5674135|reactome:R-DME-5689603|reactome:R-DME-5696394|reactome:R-DME-8856828|reactome:R-DME-8980692|reactome:R-DME-9035034 pubmed:10497190(see-also)|pubmed:2714648(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:PjIC1oHiwbQEdum3SDZnk/b7O5E7227 rogid:PCrrPzr94emHHh1y2mkp7V8yl9c7227 intact-crc:596E1D931CE91390|rigid:KYUpFZtZxkPXyeGC/ebjRZLtyM8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24020 uniprotkb:P83967 intact:EBI-85366|uniprotkb:Q24088|uniprotkb:Q9VRH0|ensemblmetazoa:FBpp0076893 intact:EBI-184828|uniprotkb:P02575|uniprotkb:P45893|uniprotkb:Q9VF62|ensemblmetazoa:FBpp0082597 psi-mi:flii_drome(display_long)|uniprotkb:fliI(gene name)|psi-mi:fliI(display_short)|uniprotkb:CG1484(orf name)|uniprotkb:Flightless-I(gene name synonym) psi-mi:act6_drome(display_long)|uniprotkb:Act88F(gene name)|psi-mi:Act88F(display_short)|uniprotkb:CG5178(orf name)|uniprotkb:Actin-88F(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871186 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0000709(gene)|ensemblmetazoa:FBtr0077192(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0007527"(adult somatic muscle development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030239"(myofibril assembly)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR029919|interpro:IPR032675|go:"GO:0005737"(cytoplasm)|refseq:NP_525097.1|flybase:FBgn0000709 refseq:NP_524367.1|flybase:FBgn0000047|ensemblmetazoa:FBgn0000047(gene)|ensemblmetazoa:FBtr0083143(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0071689"(muscle thin filament assembly)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-DME-114608|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-3928665|reactome:R-DME-4420097|reactome:R-DME-446353|reactome:R-DME-5663213|reactome:R-DME-5674135|reactome:R-DME-5689603|reactome:R-DME-5696394|reactome:R-DME-8856828|reactome:R-DME-8980692|reactome:R-DME-9035034 pubmed:9525888(see-also)|pubmed:8834811(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:e6/sa6WfmECg0wxtlDKsakvoC3Y7227 rogid:PCrrPzr94emHHh1y2mkp7V8yl9c7227 intact-crc:F2675086DAC9280A|rigid:xZQCflkoiJ7KPOz0Wb/vtZYDgmY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P25843 uniprotkb:P83967 intact:EBI-156199|uniprotkb:Q3YMV6|uniprotkb:Q9VMJ9|ensemblmetazoa:FBpp0078864|ensemblmetazoa:FBpp0078865|ensemblmetazoa:FBpp0078866|ensemblmetazoa:FBpp0089196|ensemblmetazoa:FBpp0301151|ensemblmetazoa:FBpp0301152 intact:EBI-184828|uniprotkb:P02575|uniprotkb:P45893|uniprotkb:Q9VF62|ensemblmetazoa:FBpp0082597 psi-mi:prof_drome(display_long)|uniprotkb:chic(gene name)|psi-mi:chic(display_short)|uniprotkb:chi(gene name synonym)|uniprotkb:CG9553(orf name)|uniprotkb:Protein chickadee(gene name synonym) psi-mi:act6_drome(display_long)|uniprotkb:Act88F(gene name)|psi-mi:Act88F(display_short)|uniprotkb:CG5178(orf name)|uniprotkb:Actin-88F(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871190 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245905.1|refseq:NP_001245906.1|go:"GO:0043005"(neuron projection)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0051491"(positive regulation of filopodium assembly)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR036140|refseq:NP_477016.1|refseq:NP_599131.1|refseq:NP_723136.1|refseq:NP_995635.1|flybase:FBgn0000308|ensemblmetazoa:FBgn0000308(gene)|ensemblmetazoa:FBtr0079233(transcript)|ensemblmetazoa:FBtr0079234(transcript)|ensemblmetazoa:FBtr0079235(transcript)|ensemblmetazoa:FBtr0079236(transcript)|ensemblmetazoa:FBtr0309212(transcript)|ensemblmetazoa:FBtr0309213(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007391"(dorsal closure)|go:"GO:0007420"(brain development)|go:"GO:0007436"(larval salivary gland morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0016322"(neuron remodeling)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035193"(larval central nervous system remodeling)|go:"GO:0036098"(male germ-line stem cell population maintenance)|go:"GO:0042060"(wound healing)|go:"GO:0042989"(sequestering of actin monomers)|dip:DIP-22165N refseq:NP_524367.1|flybase:FBgn0000047|ensemblmetazoa:FBgn0000047(gene)|ensemblmetazoa:FBtr0083143(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0071689"(muscle thin filament assembly)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-DME-114608|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-3928665|reactome:R-DME-4420097|reactome:R-DME-446353|reactome:R-DME-5663213|reactome:R-DME-5674135|reactome:R-DME-5689603|reactome:R-DME-5696394|reactome:R-DME-8856828|reactome:R-DME-8980692|reactome:R-DME-9035034 pubmed:1396697(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ixw/iYa5+5l7H5opccmsaYQvuY87227 rogid:PCrrPzr94emHHh1y2mkp7V8yl9c7227 intact-crc:A52450FC97F18389|rigid:8gROWpT2+aFzjhaSiugPUQmlrB8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9I7U4 uniprotkb:P18091 intact:EBI-867591|uniprotkb:O76275|uniprotkb:O76276|uniprotkb:O76277|uniprotkb:O76278|uniprotkb:O96767|uniprotkb:O96768|uniprotkb:Q7KA82|uniprotkb:Q7KAJ1|uniprotkb:Q7KPQ8|uniprotkb:Q7RTL4|uniprotkb:Q8T3N3|uniprotkb:Q9N2P7|uniprotkb:Q9N680|uniprotkb:Q9N9Y5|uniprotkb:Q9N9Y6|uniprotkb:Q9N9Y7|uniprotkb:Q9NFS3|uniprotkb:Q9NJP4|uniprotkb:Q9NL88|uniprotkb:Q9UB79|uniprotkb:Q9W055|uniprotkb:Q9XZT9|ensemblmetazoa:FBpp0072727|ensemblmetazoa:FBpp0304925 intact:EBI-244744|uniprotkb:O46044|uniprotkb:O46045|uniprotkb:Q24370|uniprotkb:Q8T024|uniprotkb:Q9W536|uniprotkb:Q9W537 psi-mi:titin_drome(display_long)|uniprotkb:D-Titin(gene name synonym)|uniprotkb:Kettin(gene name synonym)|uniprotkb:sls(gene name)|psi-mi:sls(display_short)|uniprotkb:titin(gene name synonym)|uniprotkb:CG1915(orf name) psi-mi:actn_drome(display_long)|uniprotkb:Actn(gene name)|psi-mi:Actn(display_short)|uniprotkb:fliA(gene name synonym)|uniprotkb:"l(1)2Cb"(gene name synonym)|uniprotkb:CG4376(orf name)|uniprotkb:F-actin cross-linking protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871194 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524676.2|flybase:FBgn0086906|ensemblmetazoa:FBgn0086906(gene)|ensemblmetazoa:FBtr0072848(transcript)|ensemblmetazoa:FBtr0332679(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003779"(actin binding)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007498"(mesoderm development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016203"(muscle attachment)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0031674"(I band)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0040011"(locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051301"(cell division)|interpro:IPR001452(Src homology-3)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010939(Protein of unknown function DUF1136)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|reactome:R-DME-5658623 refseq:NP_001188532.1|refseq:NP_001188533.1|refseq:NP_477484.2|refseq:NP_477485.1|refseq:NP_726784.1|flybase:FBgn0000667|refseq:NP_001259165.1|refseq:NP_001259166.1|refseq:NP_001259167.1|dip:DIP-22313N|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0030018"(Z disc)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|reactome:R-DME-114608|reactome:R-DME-438066|reactome:R-DME-446388|reactome:R-DME-9013405|reactome:R-DME-9013418|reactome:R-DME-9035034 pubmed:8335002(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KudT+8stWca6bWBIOIHz4zh5mqY7227 rogid:PBioZmfeAbvQZcNCfZG0xnIETus7227 intact-crc:5C5B1E537B08F4E4|rigid:MzEnCubHJ+BGD4Pxgg0UkM6N+8Y false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P05205 uniprotkb:P45890 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 intact:EBI-163314|uniprotkb:Q9VXQ9|ensemblmetazoa:FBpp0073983 psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:arp6_drome(display_long)|uniprotkb:Arp6(gene name)|psi-mi:Arp6(display_short)|uniprotkb:Acrp(gene name synonym)|uniprotkb:Actin-like protein 13E(gene name synonym)|uniprotkb:Actr13E(gene name synonym)|uniprotkb:Arp4(gene name synonym)|uniprotkb:CG11678(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871198 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA refseq:NP_511165.1|flybase:FBgn0011741|ensemblmetazoa:FBgn0011741(gene)|ensemblmetazoa:FBtr0074203(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043486"(histone exchange)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR030054|interpro:IPR043129|dip:DIP-17460N pubmed:9378752(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 rogid:fNEtOV1jHVnwUWXJuFmxJKcO76Y7227 intact-crc:B9551BFA46B4460F|rigid:e3DXp6zkOF8qTClg1LDNt0yQiPk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P00334 uniprotkb:P00334 intact:EBI-161843|uniprotkb:A4V0Q1|uniprotkb:Q27332|uniprotkb:Q27579|uniprotkb:Q27596|uniprotkb:Q2MGK2|uniprotkb:Q53XD5|uniprotkb:Q95TC8|uniprotkb:Q9NKC0|uniprotkb:Q9VJS3|intact:EBI-2508376|ensemblmetazoa:FBpp0100048|ensemblmetazoa:FBpp0100050|ensemblmetazoa:FBpp0100051|ensemblmetazoa:FBpp0100045|ensemblmetazoa:FBpp0100047 intact:EBI-161843|uniprotkb:A4V0Q1|uniprotkb:Q27332|uniprotkb:Q27579|uniprotkb:Q27596|uniprotkb:Q2MGK2|uniprotkb:Q53XD5|uniprotkb:Q95TC8|uniprotkb:Q9NKC0|uniprotkb:Q9VJS3|intact:EBI-2508376|ensemblmetazoa:FBpp0100048|ensemblmetazoa:FBpp0100050|ensemblmetazoa:FBpp0100051|ensemblmetazoa:FBpp0100045|ensemblmetazoa:FBpp0100047 psi-mi:adh_drome(display_long)|uniprotkb:Adh(gene name)|psi-mi:Adh(display_short)|uniprotkb:CG3481(orf name) psi-mi:adh_drome(display_long)|uniprotkb:Adh(gene name)|psi-mi:Adh(display_short)|uniprotkb:CG3481(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871210 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027266.1|refseq:NP_001027267.1|refseq:NP_001027268.1|refseq:NP_001027269.1|refseq:NP_001027270.1|flybase:FBgn0000055|ensemblmetazoa:FBtr0100589(transcript)|ensemblmetazoa:FBtr0100590(transcript)|ensemblmetazoa:FBtr0100591(transcript)|ensemblmetazoa:FBtr0100593(transcript)|ensemblmetazoa:FBtr0100594(transcript)|go:"GO:0004022"("alcohol dehydrogenase (NAD+) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0006067"(ethanol metabolic process)|go:"GO:0006069"(ethanol oxidation)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0008774"("acetaldehyde dehydrogenase (acetylating) activity")|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046164"(alcohol catabolic process)|go:"GO:0048149"(behavioral response to ethanol)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR002425(Insect alcohol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1MG5|ensemblmetazoa:FBgn0000055(gene) refseq:NP_001027266.1|refseq:NP_001027267.1|refseq:NP_001027268.1|refseq:NP_001027269.1|refseq:NP_001027270.1|flybase:FBgn0000055|ensemblmetazoa:FBtr0100589(transcript)|ensemblmetazoa:FBtr0100590(transcript)|ensemblmetazoa:FBtr0100591(transcript)|ensemblmetazoa:FBtr0100593(transcript)|ensemblmetazoa:FBtr0100594(transcript)|go:"GO:0004022"("alcohol dehydrogenase (NAD+) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0006067"(ethanol metabolic process)|go:"GO:0006069"(ethanol oxidation)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0008774"("acetaldehyde dehydrogenase (acetylating) activity")|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046164"(alcohol catabolic process)|go:"GO:0048149"(behavioral response to ethanol)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR002425(Insect alcohol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1MG5|ensemblmetazoa:FBgn0000055(gene) pubmed:7772022(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:tVhztyqyohMOHHpoF3yWO8dpQS07227 rogid:tVhztyqyohMOHHpoF3yWO8dpQS07227 intact-crc:F19F8A59899F9A44|rigid:Z+Vh97D8n2JxZ2LPXA+L3jhP4bA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24119 uniprotkb:Q8INB9 intact:EBI-867721|uniprotkb:Q24165|uniprotkb:Q8SX13|uniprotkb:Q9W0Q7|uniprotkb:A8JNH0|uniprotkb:A8WHG8|uniprotkb:Q0E8K2|ensemblmetazoa:FBpp0303179 intact:EBI-162210|uniprotkb:Q0KI65|uniprotkb:Q24293|uniprotkb:Q24469|uniprotkb:Q24470|uniprotkb:Q7JN11|uniprotkb:Q8T9A5|uniprotkb:Q9VEY7|ensemblmetazoa:FBpp0082682 psi-mi:trh_drome(display_long)|uniprotkb:trh(gene name)|psi-mi:trh(display_short)|uniprotkb:CG6883(orf name) psi-mi:akt1_drome(display_long)|uniprotkb:Akt1(gene name)|psi-mi:Akt1(display_short)|uniprotkb:CG4006(orf name)|uniprotkb:Akt(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871218 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036575.1|refseq:NP_001097461.2|refseq:NP_523872.2|flybase:FBgn0262139|refseq:NP_001261207.1|ensemblmetazoa:FBgn0262139(gene)|ensemblmetazoa:FBtr0330146(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007425"(epithelial cell fate determination, open tracheal system)|go:"GO:0007431"(salivary gland development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048736"(appendage development)|go:"GO:0072175"(epithelial tube formation)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638 refseq:NP_732113.3|refseq:NP_732114.1|refseq:NP_732115.1|flybase:FBgn0010379|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0090278"(negative regulation of peptide hormone secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR039026|reactome:R-DME-110478|reactome:R-DME-110523|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-1474151|reactome:R-DME-165158|reactome:R-DME-165159|reactome:R-DME-165181|reactome:R-DME-198323|reactome:R-DME-198693|reactome:R-DME-199418|reactome:R-DME-203615|reactome:R-DME-211163|reactome:R-DME-3769402|reactome:R-DME-389357|reactome:R-DME-389513|reactome:R-DME-392451|reactome:R-DME-450385|reactome:R-DME-450604|reactome:R-DME-5218920|reactome:R-DME-5628897|reactome:R-DME-6804759|reactome:R-DME-6811558|reactome:R-DME-69202|reactome:R-DME-69656|reactome:R-DME-8876198|reactome:R-DME-8948751|reactome:R-DME-9009391|reactome:R-DME-9604323|reactome:R-DME-9607240|reactome:R-DME-9614399|reactome:R-DME-9634638|ensemblmetazoa:FBgn0010379(gene)|ensemblmetazoa:FBtr0083228(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|refseq:NP_001287353.1|refseq:NP_001287354.1|dip:DIP-49060N pubmed:11740943(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Kpsq6NkJNU789aMg3CMeZGq2kgw7227 rogid:O+TwU/5zv00wpwqXLxtrJrHk3lw7227 intact-crc:271E4751248F5D4F|rigid:8YQQ/t8xtUdpmAcuTp+SP2fcFEo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9W0V1 uniprotkb:Q8INB9 intact:EBI-220161|uniprotkb:O62534|uniprotkb:Q0E8K9|uniprotkb:Q53XF5|uniprotkb:Q7KVE1|uniprotkb:Q8IHG6|uniprotkb:Q9W0V2|uniprotkb:Q9W0V3|ensemblmetazoa:FBpp0072366|ensemblmetazoa:FBpp0305420 intact:EBI-162210|uniprotkb:Q0KI65|uniprotkb:Q24293|uniprotkb:Q24469|uniprotkb:Q24470|uniprotkb:Q7JN11|uniprotkb:Q8T9A5|uniprotkb:Q9VEY7|ensemblmetazoa:FBpp0082682 psi-mi:pdpk1_drome(display_long)|uniprotkb:CG1210(orf name)|uniprotkb:Serine/threonine-protein kinase 61C(gene name synonym)|uniprotkb:dSTPK61(gene name synonym)|uniprotkb:Pdk1(gene name)|psi-mi:Pdk1(display_short)|uniprotkb:Pk61C(gene name synonym) psi-mi:akt1_drome(display_long)|uniprotkb:Akt1(gene name)|psi-mi:Akt1(display_short)|uniprotkb:CG4006(orf name)|uniprotkb:Akt(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871222 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525121.2|refseq:NP_728470.1|refseq:NP_728471.2|refseq:NP_728472.1|refseq:NP_728473.1|refseq:NP_728474.1|refseq:NP_728475.1|refseq:NP_728476.1|flybase:FBgn0020386|refseq:NP_001261183.1|dip:DIP-20399N|ensemblmetazoa:FBgn0020386(gene)|ensemblmetazoa:FBtr0072464(transcript)|ensemblmetazoa:FBtr0333218(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004676"(3-phosphoinositide-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033931|interpro:IPR039046|reactome:R-DME-110478|reactome:R-DME-110523|reactome:R-DME-114604|reactome:R-DME-1257604|reactome:R-DME-165158|reactome:R-DME-202424|reactome:R-DME-2730905|reactome:R-DME-389357|reactome:R-DME-392451|reactome:R-DME-5218920|reactome:R-DME-5218921|reactome:R-DME-5625740|reactome:R-DME-9634635 refseq:NP_732113.3|refseq:NP_732114.1|refseq:NP_732115.1|flybase:FBgn0010379|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0090278"(negative regulation of peptide hormone secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR039026|reactome:R-DME-110478|reactome:R-DME-110523|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-1474151|reactome:R-DME-165158|reactome:R-DME-165159|reactome:R-DME-165181|reactome:R-DME-198323|reactome:R-DME-198693|reactome:R-DME-199418|reactome:R-DME-203615|reactome:R-DME-211163|reactome:R-DME-3769402|reactome:R-DME-389357|reactome:R-DME-389513|reactome:R-DME-392451|reactome:R-DME-450385|reactome:R-DME-450604|reactome:R-DME-5218920|reactome:R-DME-5628897|reactome:R-DME-6804759|reactome:R-DME-6811558|reactome:R-DME-69202|reactome:R-DME-69656|reactome:R-DME-8876198|reactome:R-DME-8948751|reactome:R-DME-9009391|reactome:R-DME-9604323|reactome:R-DME-9607240|reactome:R-DME-9614399|reactome:R-DME-9634638|ensemblmetazoa:FBgn0010379(gene)|ensemblmetazoa:FBtr0083228(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|refseq:NP_001287353.1|refseq:NP_001287354.1|dip:DIP-49060N pubmed:11752451(see-also)|pubmed:11344272(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:dkKE+FijB301ycXfm9AMunxRckI7227 rogid:O+TwU/5zv00wpwqXLxtrJrHk3lw7227 intact-crc:CC1D8FAB0E978835|rigid:AjHOpyavqj5QJuDeADe3FF765Fk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16375 uniprotkb:Q94899 intact:EBI-131834|uniprotkb:Q8MQJ1|uniprotkb:Q8T8U4|uniprotkb:Q9VGA9|uniprotkb:Q9VGB0|ensemblmetazoa:FBpp0082036 intact:EBI-87133|uniprotkb:A4V0G9|uniprotkb:Q8MSX8|uniprotkb:Q9V3Z0|ensemblmetazoa:FBpp0079381|ensemblmetazoa:FBpp0089195|ensemblmetazoa:FBpp0308633|ensemblmetazoa:FBpp0309805 psi-mi:7up1_drome(display_long)|uniprotkb:svp(gene name)|psi-mi:svp(display_short)|uniprotkb:NR2F3(gene name synonym)|uniprotkb:CG11502(orf name)|uniprotkb:Nuclear receptor subfamily 2 group F member 3, isoforms B/C(gene name synonym) psi-mi:csn2_drome(display_long)|uniprotkb:alien(gene name)|psi-mi:alien(display_short)|uniprotkb:CSN2(gene name synonym)|uniprotkb:CG9556(orf name)|uniprotkb:Alien protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871230 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524325.1|refseq:NP_731682.1|flybase:FBgn0003651|ensemblmetazoa:FBgn0003651(gene)|ensemblmetazoa:FBtr0082564(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007419"(ventral cord development)|go:"GO:0007462"(R1/R6 cell fate commitment)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0007503"(fat body development)|go:"GO:0007507"(heart development)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014019"(neuroblast development)|go:"GO:0021782"(glial cell development)|go:"GO:0030154"(cell differentiation)|go:"GO:0042331"(phototaxis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045202"(synapse)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048856"(anatomical structure development)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|go:"GO:0007510"(cardioblast cell fate determination)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500 reactome:R-DME-5696394|reactome:R-DME-6781823|reactome:R-DME-8856825|reactome:R-DME-8951664|reactome:R-DME-9013422|ensemblmetazoa:FBgn0013746(gene)|ensemblmetazoa:FBtr0079780(transcript)|ensemblmetazoa:FBtr0079781(transcript)|ensemblmetazoa:FBtr0339550(transcript)|ensemblmetazoa:FBtr0343095(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007281"(germ cell development)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008231"(repressor ecdysone receptor complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048140"(male germ-line cyst encapsulation)|go:"GO:0048142"(germarium-derived cystoblast division)|go:"GO:0050821"(protein stabilization)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR037750|refseq:NP_523517.1|refseq:NP_723438.1|flybase:FBgn0013746|refseq:NP_001285771.1|refseq:NP_001260276.1|dip:DIP-19507N pubmed:10207062(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:mNv/8HteDK5PLx0fvNs+0pcpmhw7227 rogid:DX62U0pQ5WKA6xiVSjVhu+cBF8I7227 intact-crc:61B54B43FA3E22C8|rigid:4G3yPWMUstzdy6OeN2+dG8sZNio false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KLV9 uniprotkb:Q94899 intact:EBI-144692|intact:EBI-867766|uniprotkb:A1Z9U3|ensemblmetazoa:FBpp0086604|ensemblmetazoa:FBpp0297513 intact:EBI-87133|uniprotkb:A4V0G9|uniprotkb:Q8MSX8|uniprotkb:Q9V3Z0|ensemblmetazoa:FBpp0079381|ensemblmetazoa:FBpp0089195|ensemblmetazoa:FBpp0308633|ensemblmetazoa:FBpp0309805 psi-mi:psd11_drome(display_long)|uniprotkb:Rpn6(gene name)|psi-mi:Rpn6(display_short)|uniprotkb:26S proteasome regulatory complex subunit p42B(gene name synonym)|uniprotkb:26S proteasome regulatory subunit Rpn6(gene name synonym)|uniprotkb:CG10149(orf name) psi-mi:csn2_drome(display_long)|uniprotkb:alien(gene name)|psi-mi:alien(display_short)|uniprotkb:CSN2(gene name synonym)|uniprotkb:CG9556(orf name)|uniprotkb:Alien protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871234 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_725412.2|refseq:NP_477474.1|flybase:FBgn0028689|refseq:NP_001246325.1|dip:DIP-60004N|ensemblmetazoa:FBgn0028689(gene)|ensemblmetazoa:FBtr0087475(transcript)|ensemblmetazoa:FBtr0306558(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035295|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|rcsb pdb:3TXM|rcsb pdb:3TXN|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-6798695|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 reactome:R-DME-5696394|reactome:R-DME-6781823|reactome:R-DME-8856825|reactome:R-DME-8951664|reactome:R-DME-9013422|ensemblmetazoa:FBgn0013746(gene)|ensemblmetazoa:FBtr0079780(transcript)|ensemblmetazoa:FBtr0079781(transcript)|ensemblmetazoa:FBtr0339550(transcript)|ensemblmetazoa:FBtr0343095(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007281"(germ cell development)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008231"(repressor ecdysone receptor complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048140"(male germ-line cyst encapsulation)|go:"GO:0048142"(germarium-derived cystoblast division)|go:"GO:0050821"(protein stabilization)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR037750|refseq:NP_523517.1|refseq:NP_723438.1|flybase:FBgn0013746|refseq:NP_001285771.1|refseq:NP_001260276.1|dip:DIP-19507N pubmed:12426099(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:oMaOPtUBFny6cVUvduilZCKTGbA7227 rogid:DX62U0pQ5WKA6xiVSjVhu+cBF8I7227 intact-crc:70D59003AA55C357|rigid:hpxnu2S7b4b9kZSsE7ShHRy+bL8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P34021 uniprotkb:Q94899 intact:EBI-251199|intact:EBI-1627522|uniprotkb:Q0E9N8|uniprotkb:Q6AWL4|uniprotkb:Q8SY10|uniprotkb:Q95TS4|uniprotkb:Q9V9K8|ensemblmetazoa:FBpp0085352|ensemblmetazoa:FBpp0291631 intact:EBI-87133|uniprotkb:A4V0G9|uniprotkb:Q8MSX8|uniprotkb:Q9V3Z0|ensemblmetazoa:FBpp0079381|ensemblmetazoa:FBpp0089195|ensemblmetazoa:FBpp0308633|ensemblmetazoa:FBpp0309805 psi-mi:ecr_drome(display_long)|uniprotkb:EcR(gene name)|psi-mi:EcR(display_short)|uniprotkb:NR1H1(gene name synonym)|uniprotkb:CG1765(orf name)|uniprotkb:Ecdysteroid receptor(gene name synonym)|uniprotkb:20-hydroxy-ecdysone receptor(gene name synonym)|uniprotkb:EcRH(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 1(gene name synonym) psi-mi:csn2_drome(display_long)|uniprotkb:alien(gene name)|psi-mi:alien(display_short)|uniprotkb:CSN2(gene name synonym)|uniprotkb:CG9556(orf name)|uniprotkb:Alien protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871238 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163061.1|refseq:NP_724456.1|refseq:NP_724457.1|refseq:NP_724458.1|refseq:NP_724459.1|refseq:NP_724460.1|flybase:FBgn0000546|dip:DIP-158N|ensemblmetazoa:FBgn0000546(gene)|ensemblmetazoa:FBtr0086011(transcript)|ensemblmetazoa:FBtr0302439(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002164"(larval development)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007281"(germ cell development)|go:"GO:0007291"(sperm individualization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007552"(metamorphosis)|go:"GO:0007616"(long-term memory)|go:"GO:0008230"(ecdysone receptor holocomplex)|go:"GO:0008231"(repressor ecdysone receptor complex)|go:"GO:0008232"(activator ecdysone receptor complex)|go:"GO:0008258"(head involution)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008362"(chitin-based embryonic cuticle biosynthetic process)|go:"GO:0008544"(epidermis development)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016319"(mushroom body development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0018990"(ecdysis, chitin-based cuticle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0035053"(dorsal vessel heart proper cell fate commitment)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035073"(pupariation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035076"(ecdysone receptor-mediated signaling pathway)|go:"GO:0035100"(ecdysone binding)|go:"GO:0035180"(larval wandering behavior)|go:"GO:0035188"(hatching)|go:"GO:0035193"(larval central nervous system remodeling)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035297"(regulation of Malpighian tubule diameter)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0042220"(response to cocaine)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904799"(regulation of neuron remodeling)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003069(Ecdysteroid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR041889|rcsb pdb:1R0N|rcsb pdb:1R0O|rcsb pdb:2HAN|reactome:R-DME-159418|reactome:R-DME-383280|reactome:R-DME-4090294|reactome:R-DME-9029569|reactome:R-DME-9623433 reactome:R-DME-5696394|reactome:R-DME-6781823|reactome:R-DME-8856825|reactome:R-DME-8951664|reactome:R-DME-9013422|ensemblmetazoa:FBgn0013746(gene)|ensemblmetazoa:FBtr0079780(transcript)|ensemblmetazoa:FBtr0079781(transcript)|ensemblmetazoa:FBtr0339550(transcript)|ensemblmetazoa:FBtr0343095(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007281"(germ cell development)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008231"(repressor ecdysone receptor complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048140"(male germ-line cyst encapsulation)|go:"GO:0048142"(germarium-derived cystoblast division)|go:"GO:0050821"(protein stabilization)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR037750|refseq:NP_523517.1|refseq:NP_723438.1|flybase:FBgn0013746|refseq:NP_001285771.1|refseq:NP_001260276.1|dip:DIP-19507N pubmed:10207062(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:0BpOr5B3E7+KCZaSBnNEGFjfBYI7227 rogid:DX62U0pQ5WKA6xiVSjVhu+cBF8I7227 intact-crc:DC7AD187741DC02E|rigid:yLcECoOGX5KI7R8HQsi83BgcBNg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40417 uniprotkb:Q8SWV4 intact:EBI-867790|uniprotkb:A0A021WW06|uniprotkb:Q7PL59|uniprotkb:Q9W5M2|uniprotkb:A8Y4W1|uniprotkb:A8Y4W2|uniprotkb:Q9W5M3|ensemblmetazoa:FBpp0112423|ensemblmetazoa:FBpp0112425|ensemblmetazoa:FBpp0112426|ensemblmetazoa:FBpp0311493 intact:EBI-867774 psi-mi:erka_drome(display_long)|uniprotkb:Extracellular-regulated kinase A(gene name synonym)|uniprotkb:Protein rolled(gene name synonym)|uniprotkb:rl(gene name)|psi-mi:rl(display_short)|uniprotkb:ERKa(gene name synonym)|uniprotkb:CG12559(orf name)|uniprotkb:MAPK(gene name synonym) psi-mi:q8swv4_drome(display_long)|uniprotkb:Alk(gene name)|psi-mi:Alk(display_short)|uniprotkb:CG8250(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871242 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001015121.3|refseq:NP_001104348.2|refseq:NP_001287635.1|refseq:NP_001015122.1|refseq:NP_001015123.1|refseq:NP_001104349.1|flybase:FBgn0003256|dip:DIP-17266N|ensemblmetazoa:FBgn0003256(gene)|ensemblmetazoa:FBtr0113700(transcript)|ensemblmetazoa:FBtr0113702(transcript)|ensemblmetazoa:FBtr0113703(transcript)|ensemblmetazoa:FBtr0345337(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007362"(terminal region determination)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000826"(regulation of heart morphogenesis)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P40417|reactome:R-DME-110056|reactome:R-DME-112409|reactome:R-DME-112411|reactome:R-DME-1295596|reactome:R-DME-162658|reactome:R-DME-170968|reactome:R-DME-198753|reactome:R-DME-202670|reactome:R-DME-2029482|reactome:R-DME-2559580|reactome:R-DME-2559582|reactome:R-DME-2559585|reactome:R-DME-2871796|reactome:R-DME-3371453|reactome:R-DME-375165|reactome:R-DME-437239|reactome:R-DME-445144|reactome:R-DME-450341|reactome:R-DME-456926|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5654733|reactome:R-DME-5663213|reactome:R-DME-5673001|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5687128|reactome:R-DME-6798695|reactome:R-DME-74749|reactome:R-DME-881907|reactome:R-DME-9634635|reactome:R-DME-9634638 flybase:FBgn0040505|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0040008"(regulation of growth)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0043235"(receptor complex)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0048565"(digestive tract development)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061177"(type Is terminal bouton)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0090328"(regulation of olfactory learning)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000998(MAM)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|go:"GO:0043410"(positive regulation of MAPK cascade) pubmed:11442633(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:m7w7KhuZSyx3t+dR2TKtvx/vRtA7227 rogid:u/8XxGw3plHPH1uxEFw4dJikdN47227 intact-crc:0BF698D98266DC2D|rigid:sla1vlAQ9wccXrycO4tZPAe/ZqU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q95NU8 uniprotkb:Q8SWV4 intact:EBI-104595|uniprotkb:Q9V657|ensemblmetazoa:FBpp0087128|ensemblmetazoa:FBpp0305279 intact:EBI-867774 psi-mi:q95nu8_drome(display_long)|uniprotkb:jeb(gene name)|psi-mi:jeb(display_short)|uniprotkb:CG13180(gene name synonym)|uniprotkb:CG13182(gene name synonym)|uniprotkb:Dmel\CG30040(gene name synonym)|uniprotkb:Jeb(gene name synonym)|uniprotkb:"l(2)SH0422"(gene name synonym)|uniprotkb:"l(2)k05644"(gene name synonym)|uniprotkb:CG30040(orf name)|uniprotkb:Dmel_CG30040(orf name) psi-mi:q8swv4_drome(display_long)|uniprotkb:Alk(gene name)|psi-mi:Alk(display_short)|uniprotkb:CG8250(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871246 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610726.1|flybase:FBgn0086677|refseq:NP_001260910.1|ensemblmetazoa:FBgn0086677(gene)|ensemblmetazoa:FBtr0088021(transcript)|ensemblmetazoa:FBtr0333065(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0007522"(visceral muscle development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009986"(cell surface)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0043195"(terminal bouton)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061177"(type Is terminal bouton)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR036055|go:"GO:0005576"(extracellular region) flybase:FBgn0040505|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0040008"(regulation of growth)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0043235"(receptor complex)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0048565"(digestive tract development)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061177"(type Is terminal bouton)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0090328"(regulation of olfactory learning)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000998(MAM)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|go:"GO:0043410"(positive regulation of MAPK cascade) pubmed:14523447(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:SlCRLmYpfW1RO2i0y95yS6bwzIQ7227 rogid:u/8XxGw3plHPH1uxEFw4dJikdN47227 intact-crc:8E392F008253B675|rigid:VJepXiz81gLWXQlMyJBsyNxY+DQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16554 uniprotkb:P91926 intact:EBI-429581|uniprotkb:Q8IPE9|uniprotkb:Q961A6|uniprotkb:Q9VLB8|uniprotkb:B8A413|uniprotkb:B8A419|ensemblmetazoa:FBpp0079420|ensemblmetazoa:FBpp0308609 intact:EBI-183420|uniprotkb:O01937|uniprotkb:Q7KTZ5|uniprotkb:Q86P64|uniprotkb:Q9VPP4|uniprotkb:B3DN51|ensemblmetazoa:FBpp0088490 psi-mi:numb_drome(display_long)|uniprotkb:CG3779(orf name)|uniprotkb:numb(gene name)|psi-mi:numb(display_short) psi-mi:ap2a_drome(display_long)|uniprotkb:AP-2alpha(gene name)|psi-mi:AP-2alpha(display_short)|uniprotkb:Alpha-adaptin(gene name synonym)|uniprotkb:CG4260(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871250 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523523.2|refseq:NP_723460.1|flybase:FBgn0002973|refseq:NP_001260291.1|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051642"(centrosome localization)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|mint:P16554|go:"GO:0045178"(basal part of cell)|rcsb pdb:1DDM|rcsb pdb:2NMB|rcsb pdb:5YI7|rcsb pdb:5YI8|reactome:R-DME-5610780|reactome:R-DME-5632684|ensemblmetazoa:FBgn0002973(gene)|ensemblmetazoa:FBtr0079822(transcript)|ensemblmetazoa:FBtr0339526(transcript)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005112"(Notch binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008104"(protein localization)|go:"GO:0008347"(glial cell migration)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0045035"(sensory organ precursor cell division) refseq:NP_476819.2|refseq:NP_995607.1|flybase:FBgn0264855|ensemblmetazoa:FBgn0264855(gene)|ensemblmetazoa:FBtr0089488(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031623"(receptor internalization)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0038010"(positive regulation of signal transduction by receptor internalization)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098793"(presynapse)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990386"(mitotic cleavage furrow ingression)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|reactome:R-DME-177504|reactome:R-DME-3928665|reactome:R-DME-437239|reactome:R-DME-5099900|reactome:R-DME-5140745|reactome:R-DME-6798695|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8866427|reactome:R-DME-8964038 pubmed:12194853(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:9FGhbcAA6k1LCDHPoLSXwEEVwzY7227 rogid:1kfuoodxtoNBOjXfMpYFk1SjWAA7227 intact-crc:AC81E8C69E326E97|rigid:WheRV9UJcN8NqzUMgRSsYXvWEzI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P48148 uniprotkb:P35220 intact:EBI-87246|uniprotkb:Q0E958|uniprotkb:Q9V3J0|ensemblmetazoa:FBpp0086353|ensemblmetazoa:FBpp0086354|ensemblmetazoa:FBpp0086355|ensemblmetazoa:FBpp0086356|ensemblmetazoa:FBpp0089129|ensemblmetazoa:FBpp0089130|uniprotkb:A4UZI6 intact:EBI-126806|uniprotkb:Q960Y2|uniprotkb:Q9W5V9|ensemblmetazoa:FBpp0070037 psi-mi:rho1_drome(display_long)|uniprotkb:Rho1(gene name)|psi-mi:Rho1(display_short)|uniprotkb:CG8416(orf name) psi-mi:ctna_drome(display_long)|uniprotkb:alpha-Cat(gene name)|psi-mi:alpha-Cat(display_short)|uniprotkb:CG17947(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871254 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0014020(gene)|ensemblmetazoa:FBtr0087211(transcript)|ensemblmetazoa:FBtr0087212(transcript)|ensemblmetazoa:FBtr0087213(transcript)|ensemblmetazoa:FBtr0087214(transcript)|ensemblmetazoa:FBtr0087216(transcript)|ensemblmetazoa:FBtr0087217(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007349"(cellularization)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007374"(posterior midgut invagination)|go:"GO:0007377"(germ-band extension)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0005737"(cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0070451"(cell hair)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0110020"(regulation of actomyosin structure organization)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-193634|reactome:R-DME-198203|reactome:R-DME-2173791|reactome:R-DME-350368|reactome:R-DME-350407|reactome:R-DME-350480|reactome:R-DME-392451|reactome:R-DME-3928662|reactome:R-DME-3928663|reactome:R-DME-4086400|interpro:IPR001806(Ras GTPase)|reactome:R-DME-416482|reactome:R-DME-416572|reactome:R-DME-4420097|reactome:R-DME-450728|reactome:R-DME-5625740|reactome:R-DME-5627117|reactome:R-DME-5663220|reactome:R-DME-5666185|reactome:R-DME-5689896|reactome:R-DME-6785631|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-8980692|reactome:R-DME-9013405|reactome:R-DME-9035034|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007601"(visual perception)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035006"(melanization defense response)|go:"GO:0035099"(hemocyte migration)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035298"(regulation of Malpighian tubule size)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0042060"(wound healing)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045179"(apical cortex)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046663"(dorsal closure, leading edge cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0035149"(lumen formation, open tracheal system)|refseq:NP_477098.1|refseq:NP_599135.1|refseq:NP_599136.1|refseq:NP_725524.1|refseq:NP_995849.1|refseq:NP_995850.1|flybase:FBgn0014020|dip:DIP-22676N ensemblmetazoa:FBgn0010215(gene)|ensemblmetazoa:FBtr0070038(transcript)|go:"GO:0003383"(apical constriction)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0051015"(actin filament binding)|go:"GO:0060323"(head morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR036723|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|refseq:NP_524219.1|flybase:FBgn0010215|dip:DIP-21662N pubmed:12135916(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:DbVx4weiFRCcGfqdsUQWqWQc0Q47227 rogid:W6XeVS/IvxqgE0UQ/SyWnAmiJo87227 intact-crc:3483FBEDF67FBDD2|rigid:yNO0sIcoeNHMMMemqI8pJ48Modo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18824 uniprotkb:P35220 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 intact:EBI-126806|uniprotkb:Q960Y2|uniprotkb:Q9W5V9|ensemblmetazoa:FBpp0070037 psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:ctna_drome(display_long)|uniprotkb:alpha-Cat(gene name)|psi-mi:alpha-Cat(display_short)|uniprotkb:CG17947(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871258 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 ensemblmetazoa:FBgn0010215(gene)|ensemblmetazoa:FBtr0070038(transcript)|go:"GO:0003383"(apical constriction)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0051015"(actin filament binding)|go:"GO:0060323"(head morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR036723|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|refseq:NP_524219.1|flybase:FBgn0010215|dip:DIP-21662N pubmed:8794868(see-also)|pubmed:8943306(see-also)|pubmed:8501118(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 rogid:W6XeVS/IvxqgE0UQ/SyWnAmiJo87227 intact-crc:3F3AE2CBC7779750|rigid:znIt5ScdiMpbU67N9XG7mqiTP5g false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q23980 uniprotkb:P13395 intact:EBI-867829 intact:EBI-134595|uniprotkb:Q26340|uniprotkb:Q8SZW7|uniprotkb:Q9W085|uniprotkb:Q3KN50|ensemblmetazoa:FBpp0072672 psi-mi:q23980_drome(display_long)|uniprotkb:kst(gene name)|psi-mi:kst(display_short)|uniprotkb:CG12008(orf name) psi-mi:sptca_drome(display_long)|uniprotkb:alpha-Spec(gene name)|psi-mi:alpha-Spec(display_short)|uniprotkb:SPEC-A(gene name synonym)|uniprotkb:CG1977(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871262 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0004167|go:"GO:0003779"(actin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0042060"(wound healing)|go:"GO:0045186"(zonula adherens assembly)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|interpro:IPR041681 refseq:NP_476739.1|flybase:FBgn0250789|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|rcsb pdb:2SPC|reactome:R-DME-264870|reactome:R-DME-375165|reactome:R-DME-5673001|reactome:R-DME-6798695|reactome:R-DME-6807878|reactome:R-DME-9013420|reactome:R-DME-9013424|ensemblmetazoa:FBgn0250789(gene)|ensemblmetazoa:FBtr0072789(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007308"(oocyte construction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042062"(long-term strengthening of neuromuscular junction)|go:"GO:0045169"(fusome)|go:"GO:0045170"(spectrosome)|go:"GO:0045478"(fusome organization)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|dip:DIP-17516N pubmed:9053311(see-also)|pubmed:10652315(see-also)|pubmed:7971971(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:wUSMhW2OpE6YmC/hXRFxDxHSUqQ7227 rogid:5m/DRdFWsfhGAQEomdaubZlaD8Q7227 intact-crc:75414263003740FA|rigid:rciqusMUFyscmPwwyJIutYSVWYY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q00963 uniprotkb:P13395 intact:EBI-75025|uniprotkb:Q9VX30|uniprotkb:Q6NNX2|ensemblmetazoa:FBpp0074228 intact:EBI-134595|uniprotkb:Q26340|uniprotkb:Q8SZW7|uniprotkb:Q9W085|uniprotkb:Q3KN50|ensemblmetazoa:FBpp0072672 psi-mi:sptcb_drome(display_long)|uniprotkb:beta-Spec(gene name)|psi-mi:beta-Spec(display_short)|uniprotkb:Spec-b(gene name synonym)|uniprotkb:CG5870(orf name) psi-mi:sptca_drome(display_long)|uniprotkb:alpha-Spec(gene name)|psi-mi:alpha-Spec(display_short)|uniprotkb:SPEC-A(gene name synonym)|uniprotkb:CG1977(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871266 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523388.1|flybase:FBgn0250788|dip:DIP-18565N|ensemblmetazoa:FBgn0250788(gene)|ensemblmetazoa:FBtr0074454(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008091"(spectrin)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042062"(long-term strengthening of neuromuscular junction)|go:"GO:0045169"(fusome)|go:"GO:0045170"(spectrosome)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051693"(actin filament capping)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:1903729"(regulation of plasma membrane organization)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|rcsb pdb:1DRO|reactome:R-DME-375165|reactome:R-DME-5673001|reactome:R-DME-6807878|reactome:R-DME-9013420|reactome:R-DME-9013424 refseq:NP_476739.1|flybase:FBgn0250789|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|rcsb pdb:2SPC|reactome:R-DME-264870|reactome:R-DME-375165|reactome:R-DME-5673001|reactome:R-DME-6798695|reactome:R-DME-6807878|reactome:R-DME-9013420|reactome:R-DME-9013424|ensemblmetazoa:FBgn0250789(gene)|ensemblmetazoa:FBtr0072789(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007308"(oocyte construction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042062"(long-term strengthening of neuromuscular junction)|go:"GO:0045169"(fusome)|go:"GO:0045170"(spectrosome)|go:"GO:0045478"(fusome organization)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|dip:DIP-17516N pubmed:7971971(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:gizANuEfb65JEEEUcIPeAIukXS87227 rogid:5m/DRdFWsfhGAQEomdaubZlaD8Q7227 intact-crc:94E65B059607AAE8|rigid:0ZQy9+PSwJW3V9ZRra5GW/oI1iU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20480 uniprotkb:P06605 intact:EBI-84482|uniprotkb:Q9VAG8|ensemblmetazoa:FBpp0084900|ensemblmetazoa:FBpp0311231 intact:EBI-118791|uniprotkb:Q9VIB8|ensemblmetazoa:FBpp0081062 psi-mi:ncd_drome(display_long)|uniprotkb:ncd(gene name)|psi-mi:ncd(display_short)|uniprotkb:"CA(ND)"(gene name synonym)|uniprotkb:CG7831(orf name) psi-mi:tba3_drome(display_long)|uniprotkb:alphaTub84D(gene name)|psi-mi:alphaTub84D(display_short)|uniprotkb:TubA84D(gene name synonym)|uniprotkb:CG2512(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871270 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0031534"(minus-end directed microtubule sliding)|go:"GO:0032837"(distributive segregation)|ensemblmetazoa:FBtr0344976(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0072687"(meiotic spindle)|ensemblmetazoa:FBgn0002924(gene)|ensemblmetazoa:FBtr0085534(transcript)|rcsb pdb:3U06|rcsb pdb:5HLE|rcsb pdb:5HNW|rcsb pdb:5HNX|rcsb pdb:5HNY|rcsb pdb:5HNZ|rcsb pdb:5W3D|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:1CZ7|rcsb pdb:1N6M|rcsb pdb:1OZX|rcsb pdb:1SYJ|rcsb pdb:1SYP|rcsb pdb:1SZ4|rcsb pdb:1SZ5|rcsb pdb:2NCD|rcsb pdb:3L1C|refseq:NP_476651.1|flybase:FBgn0002924|refseq:NP_001287592.1|dip:DIP-21302N refseq:NP_524264.1|flybase:FBgn0003885|ensemblmetazoa:FBgn0003885(gene)|ensemblmetazoa:FBtr0081538(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0017022"(myosin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-DME-3371497|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811436|reactome:R-DME-983189|dip:DIP-23082N pubmed:7597061(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8sydvdYOvP3j1aqufTIH/rvDyJw7227 rogid:xYYhBw+1ChuZabXpl8W4SSWuCnA7227 intact-crc:CFA9AA0C3B0B16C4|rigid:Qzd2m8NK8sTbejH6Bli4A0ldb9E false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P17210 uniprotkb:P06605 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 intact:EBI-118791|uniprotkb:Q9VIB8|ensemblmetazoa:FBpp0081062 psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:tba3_drome(display_long)|uniprotkb:alphaTub84D(gene name)|psi-mi:alphaTub84D(display_short)|uniprotkb:TubA84D(gene name synonym)|uniprotkb:CG2512(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871274 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N refseq:NP_524264.1|flybase:FBgn0003885|ensemblmetazoa:FBgn0003885(gene)|ensemblmetazoa:FBtr0081538(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0017022"(myosin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-DME-3371497|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811436|reactome:R-DME-983189|dip:DIP-23082N pubmed:7597061(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 rogid:xYYhBw+1ChuZabXpl8W4SSWuCnA7227 intact-crc:751F0D4980F8B263|rigid:DcAlFtZjuto8sfQgbem7AkC27is false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P61857 uniprotkb:P06605 intact:EBI-177290|uniprotkb:P08840|uniprotkb:P22247|uniprotkb:Q540X8|uniprotkb:Q9VHE1|ensemblmetazoa:FBpp0081524 intact:EBI-118791|uniprotkb:Q9VIB8|ensemblmetazoa:FBpp0081062 psi-mi:tbb2_drome(display_long)|uniprotkb:CG9359(orf name)|uniprotkb:betaTub85D(gene name)|psi-mi:betaTub85D(display_short)|uniprotkb:TubB85D(gene name synonym)|uniprotkb:Beta-2-tubulin(gene name synonym) psi-mi:tba3_drome(display_long)|uniprotkb:alphaTub84D(gene name)|psi-mi:alphaTub84D(display_short)|uniprotkb:TubA84D(gene name synonym)|uniprotkb:CG2512(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871278 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524290.2|flybase:FBgn0003889|ensemblmetazoa:FBgn0003889(gene)|ensemblmetazoa:FBtr0082046(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007435"(salivary gland morphogenesis)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-DME-3371497|reactome:R-DME-5620924|reactome:R-DME-6798695|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811436|reactome:R-DME-983189 refseq:NP_524264.1|flybase:FBgn0003885|ensemblmetazoa:FBgn0003885(gene)|ensemblmetazoa:FBtr0081538(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0017022"(myosin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-DME-3371497|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811436|reactome:R-DME-983189|dip:DIP-23082N pubmed:2498648(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:cw3Wq70a/ZvnMJfB7TgIuN64tVQ7227 rogid:xYYhBw+1ChuZabXpl8W4SSWuCnA7227 intact-crc:7A1103D17AB7D945|rigid:42AfzlSavZJBXAIg6H5OKmrM69M false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08841 uniprotkb:P06604 intact:EBI-189050|uniprotkb:Q6I8M0|uniprotkb:Q6I8M1|uniprotkb:Q9W184|ensemblmetazoa:FBpp0072177 intact:EBI-96321|uniprotkb:Q8MYS4|uniprotkb:Q9VH86|uniprotkb:B5RJ60|ensemblmetazoa:FBpp0081565 psi-mi:tbb3_drome(display_long)|uniprotkb:betaTub60D(gene name)|psi-mi:betaTub60D(display_short)|uniprotkb:TubB60C(gene name synonym)|uniprotkb:CG3401(orf name)|uniprotkb:Beta-3-tubulin(gene name synonym) psi-mi:tba2_drome(display_long)|uniprotkb:alphaTub85E(gene name)|psi-mi:alphaTub85E(display_short)|uniprotkb:TUBA85E(gene name synonym)|uniprotkb:CG9476(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871282 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523842.2|flybase:FBgn0003888|ensemblmetazoa:FBgn0003888(gene)|ensemblmetazoa:FBtr0072270(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0009416"(response to light stimulus)|go:"GO:0030537"(larval behavior)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-DME-3371497|reactome:R-DME-5620924|reactome:R-DME-6798695|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811436|reactome:R-DME-983189 refseq:NP_524297.1|flybase:FBgn0003886|ensemblmetazoa:FBgn0003886(gene)|ensemblmetazoa:FBtr0082087(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0009826"(unidimensional cell growth)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-DME-3371497|reactome:R-DME-5620924|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811436|reactome:R-DME-983189 pubmed:9188100(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:CKRrT1c58wDOHgyLYCxig4uzMQ47227 rogid:1cE++o20q2tQt2B62zjTAocCw3Y7227 intact-crc:CF7598578C9E386F|rigid:J0Mdl2cIHRl2KNIxR73yln5srCM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P23654 uniprotkb:P15364 intact:EBI-137161|uniprotkb:A4V209|uniprotkb:Q9V3F0|ensemblmetazoa:FBpp0075081|ensemblmetazoa:FBpp0075082|ensemblmetazoa:FBpp0292987 intact:EBI-195387|uniprotkb:Q9V3A5|ensemblmetazoa:FBpp0081136|ensemblmetazoa:FBpp0081137 psi-mi:nrt_drome(display_long)|uniprotkb:Nrt(gene name)|psi-mi:Nrt(display_short)|uniprotkb:CG9704(orf name) psi-mi:amal_drome(display_long)|uniprotkb:Ama(gene name)|psi-mi:Ama(display_short)|uniprotkb:CG2198(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871286 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189121.1|refseq:NP_476798.1|refseq:NP_730196.1|flybase:FBgn0004108|ensemblmetazoa:FBgn0004108(gene)|ensemblmetazoa:FBtr0075322(transcript)|ensemblmetazoa:FBtr0075323(transcript)|ensemblmetazoa:FBtr0304018(transcript)|go:"GO:0004895"(cell adhesion receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030424"(axon)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|interpro:IPR029058|reactome:R-DME-112311|reactome:R-DME-1483191|reactome:R-DME-2022377|reactome:R-DME-211945|reactome:R-DME-8964038 refseq:NP_476579.1|refseq:NP_788589.1|flybase:FBgn0000071|dip:DIP-19577N|ensemblmetazoa:FBgn0000071(gene)|ensemblmetazoa:FBtr0081619(transcript)|ensemblmetazoa:FBtr0081620(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:1903977"(positive regulation of glial cell migration)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179 pubmed:10970840(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:MhK2aqUT3zLn+a+E8vb63QMC3hM7227 rogid:tkBDCZkNjj2JJo1AuVi+ckbvGnk7227 intact-crc:E9EB8EC128277F0A|rigid:w/LSSQ214wH6TaxOQqsc8sYu00g false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P11420 uniprotkb:Q9Y0A7 intact:EBI-151268|intact:EBI-1639097|uniprotkb:Q9VKX3|ensemblmetazoa:FBpp0079598|ensemblmetazoa:FBpp0304504|ensemblmetazoa:FBpp0304505 intact:EBI-92598|uniprotkb:Q0IGQ5|uniprotkb:Q9VJ76|ensemblmetazoa:FBpp0080631 psi-mi:da_drome(display_long)|uniprotkb:da(gene name)|psi-mi:da(display_short)|uniprotkb:CG5102(orf name) psi-mi:amos_drome(display_long)|uniprotkb:amos(gene name)|psi-mi:amos(display_short)|uniprotkb:Roi(gene name synonym)|uniprotkb:rolo(gene name synonym)|uniprotkb:Reduced olfactory organs protein(gene name synonym)|uniprotkb:Absent MD neurons and olfactory sensilla protein(gene name synonym)|uniprotkb:Rough eye protein(gene name synonym)|uniprotkb:CG10393(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871290 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007423"(sensory organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030237"(female sex determination)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050821"(protein stabilization)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-525793|reactome:R-DME-8939236|go:"GO:0061525"(hindgut development)|flybase:FBgn0267821|ensemblmetazoa:FBgn0267821(gene)|ensemblmetazoa:FBtr0080008(transcript)|ensemblmetazoa:FBtr0332195(transcript)|ensemblmetazoa:FBtr0332196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_477189.1|refseq:NP_001260340.1|refseq:NP_001260341.1|dip:DIP-50N refseq:NP_477446.1|flybase:FBgn0003270|ensemblmetazoa:FBgn0003270(gene)|ensemblmetazoa:FBtr0081081(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007423"(sensory organ development)|go:"GO:0008052"(sensory organ boundary specification)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048813"(dendrite morphogenesis)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-18188N pubmed:10707972(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:EwPK9ObnWH1gzRFPpERKnmw/kDA7227 rogid:VNcCkqErxrwJ5Du4UkZgZ6lR4ME7227 intact-crc:CC17915D93DD6E5A|rigid:5wjAcpO6cSkfL5xf9oY/IClDrQI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20241 uniprotkb:Q24241 intact:EBI-246403|uniprotkb:A4V452|uniprotkb:Q1WWD5|uniprotkb:O61541|uniprotkb:O61542|uniprotkb:Q24414|uniprotkb:Q24415|uniprotkb:Q95U64|uniprotkb:Q9V3X0|ensemblmetazoa:FBpp0071155|ensemblmetazoa:FBpp0290977|ensemblmetazoa:FBpp0305703 intact:EBI-867848 psi-mi:nrg_drome(display_long)|uniprotkb:Nrg(gene name)|psi-mi:Nrg(display_short)|uniprotkb:CG1634(orf name) psi-mi:q24241_drome(display_long)|uniprotkb:Ank(gene name)|psi-mi:Ank(display_short)|uniprotkb:CG1651(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871294 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162704.1|refseq:NP_001162705.1|refseq:NP_001162706.1|refseq:NP_511090.1|refseq:NP_727274.1|refseq:NP_996380.1|refseq:NP_001259336.1|refseq:NP_001259337.1|flybase:FBgn0264975|dip:DIP-22412N|ensemblmetazoa:FBgn0264975(gene)|ensemblmetazoa:FBtr0071208(transcript)|ensemblmetazoa:FBtr0301763(transcript)|ensemblmetazoa:FBtr0333523(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0005919"(pleated septate junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007560"(imaginal disc morphogenesis)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008050"(female courtship behavior)|go:"GO:0008366"(axon ensheathment)|go:"GO:0016319"(mushroom body development)|go:"GO:0019991"(septate junction assembly)|go:"GO:0021682"(nerve maturation)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035151"(regulation of tube size, open tracheal system)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045924"(regulation of female receptivity)|go:"GO:0048036"(central complex development)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0061343"(cell adhesion involved in heart morphogenesis)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1CFB flybase:FBgn0011747|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0030507"(spectrin binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045170"(spectrosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR040745 pubmed:9660878(see-also)|pubmed:8636238(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:mVe48Pr6nHN93iyxEWD3zUsZoPM7227 rogid:S43Xm0MFlaERoBfgea4ca2KLH847227 intact-crc:17F26C17A7E774F2|rigid:wBGwXPu/olXnirpHtwrQhWPkmbE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O18381 uniprotkb:P02833 intact:EBI-232318|uniprotkb:Q8ST91|uniprotkb:Q8ST92|uniprotkb:Q9V4F5 intact:EBI-200869|intact:EBI-1629206|uniprotkb:Q95SZ6|ensemblmetazoa:FBpp0081161|ensemblmetazoa:FBpp0081162|ensemblmetazoa:FBpp0089245|ensemblmetazoa:FBpp0089246 psi-mi:pax6_drome(display_long)|uniprotkb:ey(gene name)|psi-mi:ey(display_short)|uniprotkb:pax6(gene name synonym)|uniprotkb:CG1464(orf name)|uniprotkb:Protein eyeless(gene name synonym) psi-mi:antp_drome(display_long)|uniprotkb:Antp(gene name)|psi-mi:Antp(display_short)|uniprotkb:CG1028(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871298 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524628.2|refseq:NP_726607.1|flybase:FBgn0005558|dip:DIP-46285N|go:"GO:0043704"(photoreceptor cell fate specification)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048036"(central complex development)|go:"GO:0048749"(compound eye development)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048856"(anatomical structure development)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|reactome:R-DME-8939245|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0016319"(mushroom body development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway) refseq:NP_996176.1|flybase:FBgn0260642|refseq:NP_996167.1|refseq:NP_996168.1|refseq:NP_996170.1|refseq:NP_996175.1|dip:DIP-51405N|ensemblmetazoa:FBgn0260642(gene)|ensemblmetazoa:FBtr0081647(transcript)|ensemblmetazoa:FBtr0081652(transcript)|ensemblmetazoa:FBtr0081654(transcript)|ensemblmetazoa:FBtr0081655(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007383"(specification of segmental identity, antennal segment)|go:"GO:0007384"(specification of segmental identity, thorax)|go:"GO:0007419"(ventral cord development)|go:"GO:0007494"(midgut development)|go:"GO:0007507"(heart development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014019"(neuroblast development)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048542"(lymph gland development)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|rcsb pdb:1AHD|rcsb pdb:1HOM|rcsb pdb:1KZ0|rcsb pdb:1KZ5|rcsb pdb:1OMQ|rcsb pdb:1SAN|rcsb pdb:2HOA|rcsb pdb:2ND6|rcsb pdb:2ND7|rcsb pdb:2ND8|rcsb pdb:4XIC|rcsb pdb:4XID|rcsb pdb:5JLW|rcsb pdb:5JLX|rcsb pdb:9ANT pubmed:11179224(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:5c/N+xgYitvP49d/QbUAWYs7J+A7227 rogid:geGhJqYPEcOnpw1Nys1+5+t7Nu87227 intact-crc:52E02CAC565DEC0C|rigid:MWy13wmdmgVd+koB7RdAJ8K7aSg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08181 uniprotkb:P02833 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 intact:EBI-200869|intact:EBI-1629206|uniprotkb:Q95SZ6|ensemblmetazoa:FBpp0081161|ensemblmetazoa:FBpp0081162|ensemblmetazoa:FBpp0089245|ensemblmetazoa:FBpp0089246 psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:antp_drome(display_long)|uniprotkb:Antp(gene name)|psi-mi:Antp(display_short)|uniprotkb:CG1028(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871302 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N refseq:NP_996176.1|flybase:FBgn0260642|refseq:NP_996167.1|refseq:NP_996168.1|refseq:NP_996170.1|refseq:NP_996175.1|dip:DIP-51405N|ensemblmetazoa:FBgn0260642(gene)|ensemblmetazoa:FBtr0081647(transcript)|ensemblmetazoa:FBtr0081652(transcript)|ensemblmetazoa:FBtr0081654(transcript)|ensemblmetazoa:FBtr0081655(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007383"(specification of segmental identity, antennal segment)|go:"GO:0007384"(specification of segmental identity, thorax)|go:"GO:0007419"(ventral cord development)|go:"GO:0007494"(midgut development)|go:"GO:0007507"(heart development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014019"(neuroblast development)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048542"(lymph gland development)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|rcsb pdb:1AHD|rcsb pdb:1HOM|rcsb pdb:1KZ0|rcsb pdb:1KZ5|rcsb pdb:1OMQ|rcsb pdb:1SAN|rcsb pdb:2HOA|rcsb pdb:2ND6|rcsb pdb:2ND7|rcsb pdb:2ND8|rcsb pdb:4XIC|rcsb pdb:4XID|rcsb pdb:5JLW|rcsb pdb:5JLX|rcsb pdb:9ANT pubmed:9171376(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 rogid:geGhJqYPEcOnpw1Nys1+5+t7Nu87227 intact-crc:A3E889E8E69CAB01|rigid:iD4Z6KAloFyC+l8/lf85mmrUAoM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q01842 uniprotkb:Q7K119 intact:EBI-161142|uniprotkb:Q6AWH6|uniprotkb:Q6NR43|uniprotkb:Q9VQ81|ensemblmetazoa:FBpp0077522|ensemblmetazoa:FBpp0077523|ensemblmetazoa:FBpp0303508|ensemblmetazoa:FBpp0303509|ensemblmetazoa:FBpp0303510 intact:EBI-153260|ensemblmetazoa:FBpp0085834 psi-mi:pok_drome(display_long)|uniprotkb:aop(gene name)|psi-mi:aop(display_short)|uniprotkb:pok(gene name synonym)|uniprotkb:Yan(gene name synonym)|uniprotkb:CG3166(orf name)|uniprotkb:Protein yan(gene name synonym)|uniprotkb:Protein anterior open(gene name synonym) psi-mi:q7k119_drome(display_long)|uniprotkb:edl(gene name)|psi-mi:edl(display_short)|uniprotkb:mae(gene name synonym)|uniprotkb:Dmel_CG15085(orf name)|uniprotkb:CG15085(orf name)|uniprotkb:Dmel\CG15085(gene name synonym)|uniprotkb:EDL(gene name synonym)|uniprotkb:Edl(gene name synonym)|uniprotkb:MAE(gene name synonym)|uniprotkb:Mae(gene name synonym)|uniprotkb:anon-WO02077276.2(gene name synonym)|uniprotkb:anon-WO02077276.3(gene name synonym)|uniprotkb:"l(2)k06602"(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871306 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001259908.1|refseq:NP_001259909.1|refseq:NP_001259910.1|refseq:NP_523455.2|refseq:NP_722766.1|flybase:FBgn0000097|interpro:IPR036390|rcsb pdb:1SV0|rcsb pdb:1SV4|interpro:IPR036388|reactome:R-DME-8939245|ensemblmetazoa:FBgn0000097(gene)|ensemblmetazoa:FBtr0077850(transcript)|ensemblmetazoa:FBtr0077851(transcript)|ensemblmetazoa:FBtr0330658(transcript)|ensemblmetazoa:FBtr0330659(transcript)|ensemblmetazoa:FBtr0330660(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008406"(gonad development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0035155"(negative regulation of terminal cell fate specification, open tracheal system)|go:"GO:0035157"(negative regulation of fusion cell fate specification)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045677"(negative regulation of R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0055001"(muscle cell development)|go:"GO:0060233"(oenocyte delamination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR033077|dip:DIP-20916N refseq:NP_523786.2|flybase:FBgn0023214|ensemblmetazoa:FBgn0023214(gene)|ensemblmetazoa:FBtr0086652(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007423"(sensory organ development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051168"(nuclear export)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|rcsb pdb:1SV0 pubmed:11357138(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:TmF41pskIuNP00YZZEl+POr0mjc7227 rogid:4+ndBArru+Cv4mro1b4PdSPgFUQ7227 intact-crc:745BCC39DD3B592C|rigid:WxYwbYiDnuDdbTifp1AfAilnBNk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KJV6 uniprotkb:Q7KJV5 intact:EBI-867875 intact:EBI-867865 psi-mi:q7kjv6_drome(display_long)|uniprotkb:Uba2(gene name)|psi-mi:Uba2(display_short)|uniprotkb:CG7528(orf name) psi-mi:q7kjv5_drome(display_long)|uniprotkb:Aos1(gene name)|psi-mi:Aos1(display_short)|uniprotkb:CG12276(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871310 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0029113|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033134"(ubiquitin activating enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR019572|interpro:IPR023318|interpro:IPR028077|interpro:IPR030661|interpro:IPR033127|interpro:IPR035985|interpro:IPR042449 flybase:FBgn0029512|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033134"(ubiquitin activating enzyme binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985 pubmed:11884525(see-also)|pubmed:10995744(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6hSWdsAvG5y2/bW1XcSHzO+1b0A7227 rogid:rew81zlhM7A270L/SEaQT65AQog7227 intact-crc:E21CF91134B1AE92|rigid:XJ/tiLAf5v3yBs2g747mRWTZPNo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O97102 uniprotkb:Q7KJV5 intact:EBI-114439|ensemblmetazoa:FBpp0078984|ensemblmetazoa:FBpp0312327 intact:EBI-867865 psi-mi:o97102_drome(display_long)|uniprotkb:smt3(gene name)|psi-mi:smt3(display_short)|uniprotkb:Smt3(gene name synonym)|uniprotkb:DmSUMO-1(gene name synonym)|uniprotkb:Dm0342(gene name synonym)|uniprotkb:DmSmt3(gene name synonym)|uniprotkb:Dmel\CG4494(gene name synonym)|uniprotkb:Dmsmt3(gene name synonym)|uniprotkb:SMT3(gene name synonym)|uniprotkb:SUMO(gene name synonym)|uniprotkb:Sumo(gene name synonym)|uniprotkb:"anon-EST:Posey240"(gene name synonym)|uniprotkb:dSmt3(gene name synonym)|uniprotkb:dsmt3(gene name synonym)|uniprotkb:"l(2)04493"(gene name synonym)|uniprotkb:"l(2)SH0182"(gene name synonym)|uniprotkb:"l(2)SH2 0182"(gene name synonym)|uniprotkb:CG4494(orf name)|uniprotkb:sumo(gene name synonym)|uniprotkb:Dmel_CG4494(orf name) psi-mi:q7kjv5_drome(display_long)|uniprotkb:Aos1(gene name)|psi-mi:Aos1(display_short)|uniprotkb:CG12276(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871314 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477411.1|go:"GO:0000940"(outer kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|ensemblmetazoa:FBgn0264922(gene)|ensemblmetazoa:FBtr0079356(transcript)|ensemblmetazoa:FBtr0346716(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016925"(protein sumoylation)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030496"(midbody)|go:"GO:0031386"(protein tag)|go:"GO:0035073"(pupariation)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:O97102|rcsb pdb:2K1F|reactome:R-DME-196791|reactome:R-DME-3065679|reactome:R-DME-3108214|reactome:R-DME-3232118|reactome:R-DME-3899300|reactome:R-DME-4090294|reactome:R-DME-4551638|reactome:R-DME-4570464|reactome:R-DME-4615885|reactome:R-DME-4755510|reactome:R-DME-5696395|refseq:NP_001303312.1|flybase:FBgn0264922 flybase:FBgn0029512|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033134"(ubiquitin activating enzyme binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985 pubmed:10660560(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:fqo3Y86DDI0SsWGEfanaOs8qJlk7227 rogid:rew81zlhM7A270L/SEaQT65AQog7227 intact-crc:C7FFEDFC0848D6D8|rigid:yS1aaAtYWIhMVvhHQShsU/zeNbk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O18353 uniprotkb:P29673 intact:EBI-130074|ensemblmetazoa:FBpp0072100 intact:EBI-132187|uniprotkb:Q8T9D4|uniprotkb:Q9V9H5|ensemblmetazoa:FBpp0085394 psi-mi:o18353_drome(display_long)|uniprotkb:Chi(gene name)|psi-mi:Chi(display_short)|uniprotkb:Chip(gene name synonym)|uniprotkb:CHIP(gene name synonym)|uniprotkb:Dmel\CG3924(gene name synonym)|uniprotkb:LDB(gene name synonym)|uniprotkb:Ldb(gene name synonym)|uniprotkb:chi(gene name synonym)|uniprotkb:chip(gene name synonym)|uniprotkb:dLDB(gene name synonym)|uniprotkb:dLdb(gene name synonym)|uniprotkb:"l(2)04405"(gene name synonym)|uniprotkb:"l(2)k04405"(gene name synonym)|uniprotkb:CG3924(orf name)|uniprotkb:Dmel_CG3924(orf name) psi-mi:apte_drome(display_long)|uniprotkb:ap(gene name)|psi-mi:ap(display_short)|uniprotkb:CG8376(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871318 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477082.1|flybase:FBgn0013764|ensemblmetazoa:FBgn0013764(gene)|ensemblmetazoa:FBtr0072191(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007563"(regulation of eclosion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030274"(LIM domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070983"(dendrite guidance)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|go:"GO:0010468"(regulation of gene expression) refseq:NP_001163058.1|refseq:NP_001163059.1|refseq:NP_523621.2|refseq:NP_724428.1|flybase:FBgn0267978|ensemblmetazoa:FBgn0267978(gene)|ensemblmetazoa:FBtr0086058(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007419"(ventral cord development)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007451"(dorsal/ventral lineage restriction, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007517"(muscle organ development)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035218"(leg disc development)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048735"(haltere morphogenesis)|go:"GO:0060033"(anatomical structure regression)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|dip:DIP-23617N pubmed:10488342(see-also)|pubmed:10751171(see-also)|pubmed:9744867(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:czIwVtaJWBnWCANwkEZHnvpMrn87227 rogid:e72zyyK4Zw75ECbFKzjOos3c8LU7227 intact-crc:759B5783BB8CB92F|rigid:vroxkpLRMV97geYt+nxpv1oeNbg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O77284 uniprotkb:P29673 intact:EBI-102434|ensemblmetazoa:FBpp0309322|ensemblmetazoa:FBpp0309324 intact:EBI-132187|uniprotkb:Q8T9D4|uniprotkb:Q9V9H5|ensemblmetazoa:FBpp0085394 psi-mi:o77284_drome(display_long)|uniprotkb:Bx(gene name)|psi-mi:Bx(display_short)|uniprotkb:beadex/dLMO(gene name synonym)|uniprotkb:CG44425(orf name)|uniprotkb:CG10548(gene name synonym)|uniprotkb:CG15048(gene name synonym)|uniprotkb:CG6500(gene name synonym)|uniprotkb:Bd(gene name synonym)|uniprotkb:DLMO(gene name synonym)|uniprotkb:Dlmo(gene name synonym)|uniprotkb:Dmel\CG44425(gene name synonym)|uniprotkb:LMO(gene name synonym)|uniprotkb:Lmo(gene name synonym)|uniprotkb:Ptd(gene name synonym)|uniprotkb:Rho(gene name synonym)|uniprotkb:beadex(gene name synonym)|uniprotkb:dLMO(gene name synonym)|uniprotkb:dLmo(gene name synonym)|uniprotkb:dlmo(gene name synonym)|uniprotkb:dttg(gene name synonym)|uniprotkb:fliH(gene name synonym)|uniprotkb:hdp(gene name synonym)|uniprotkb:hdp-a(gene name synonym)|uniprotkb:hld(gene name synonym)|uniprotkb:Dmel_CG44425(orf name)|uniprotkb:bx(gene name synonym) psi-mi:apte_drome(display_long)|uniprotkb:ap(gene name)|psi-mi:ap(display_short)|uniprotkb:CG8376(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871322 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0265598|ensemblmetazoa:FBgn0265598(gene)|ensemblmetazoa:FBtr0340364(transcript)|ensemblmetazoa:FBtr0340366(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0022414"(reproductive process)|go:"GO:0022416"(chaeta development)|go:"GO:0035218"(leg disc development)|go:"GO:0035483"(gastric emptying)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0042220"(response to cocaine)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_728184.1|refseq:NP_788931.1 refseq:NP_001163058.1|refseq:NP_001163059.1|refseq:NP_523621.2|refseq:NP_724428.1|flybase:FBgn0267978|ensemblmetazoa:FBgn0267978(gene)|ensemblmetazoa:FBtr0086058(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007419"(ventral cord development)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007451"(dorsal/ventral lineage restriction, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007517"(muscle organ development)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035218"(leg disc development)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048735"(haltere morphogenesis)|go:"GO:0060033"(anatomical structure regression)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|dip:DIP-23617N pubmed:10488342(see-also)|pubmed:9744867(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:lGhKJs2Y1NCdzMNHZN4pVD9JHuo7227 rogid:e72zyyK4Zw75ECbFKzjOos3c8LU7227 intact-crc:6FF9102C36DA865B|rigid:p3IPRqM4RAJKaYuov6HvDcRnaNk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VDG2 uniprotkb:O62530 intact:EBI-173258|uniprotkb:O96392|uniprotkb:Q8MZ58|ensemblmetazoa:FBpp0083406 intact:EBI-102705|ensemblmetazoa:FBpp0291080|ensemblmetazoa:FBpp0083646|ensemblmetazoa:FBpp0083645 psi-mi:rlip_drome(display_long)|uniprotkb:Rlip(gene name)|psi-mi:Rlip(display_short)|uniprotkb:CG11622(orf name)|uniprotkb:Ral-interacting protein 1(gene name synonym) psi-mi:o62530_drome(display_long)|uniprotkb:AP2mu2(gene name synonym)|uniprotkb:Dmel\CG7057(gene name synonym)|uniprotkb:Dmu2(gene name synonym)|uniprotkb:"MENE (3R)-D"(gene name synonym)|uniprotkb:"MENE(3R)-D"(gene name synonym)|uniprotkb:"anon-EST:Posey50"(gene name synonym)|uniprotkb:anon-WO0172774.104(gene name synonym)|uniprotkb:apm4(gene name synonym)|uniprotkb:mu2(gene name synonym)|uniprotkb:AP-2mu(gene name)|psi-mi:AP-2mu(display_short)|uniprotkb:AP-50(gene name synonym)|uniprotkb:AP50(gene name synonym)|uniprotkb:cg7057(gene name synonym)|uniprotkb:mu2-ada(gene name synonym)|uniprotkb:CG7057(orf name)|uniprotkb:Dmel_CG7057(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871326 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650933.2|flybase:FBgn0026056|ensemblmetazoa:FBgn0026056(gene)|ensemblmetazoa:FBtr0084002(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046578"(regulation of Ras protein signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|reactome:R-DME-9013148|reactome:R-DME-9013149 refseq:NP_001163686.1|refseq:NP_651049.3|refseq:NP_732744.1|flybase:FBgn0263351|reactome:R-DME-8964038|ensemblmetazoa:FBtr0084252(transcript)|ensemblmetazoa:FBtr0084253(transcript)|ensemblmetazoa:FBtr0301866(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR043512|interpro:IPR043532|reactome:R-DME-177504|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-3928665|reactome:R-DME-437239|reactome:R-DME-5099900|reactome:R-DME-5140745|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8866427|ensemblmetazoa:FBgn0263351(gene) pubmed:10910768(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:yFklQl4olbZi9X62QgjH3VbyGzE7227 rogid:LU5cJDanbVnzxxIJSKAOWfRS6vE7227 intact-crc:EDB9C12323E3774C|rigid:QFPIR5iyP+hb7/XJK6qtKSeLPCU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18431 uniprotkb:Q961B0 intact:EBI-242141|uniprotkb:O76881|uniprotkb:P23646|uniprotkb:Q27603|uniprotkb:Q27604|uniprotkb:Q27605|uniprotkb:Q8MRF7|uniprotkb:Q9NF42|uniprotkb:Q9U094|uniprotkb:Q9W4X3|ensemblmetazoa:FBpp0070449|ensemblmetazoa:FBpp0070451|ensemblmetazoa:FBpp0070452|ensemblmetazoa:FBpp0070453|ensemblmetazoa:FBpp0089158|ensemblmetazoa:FBpp0089162 intact:EBI-867895 psi-mi:sgg_drome(display_long)|uniprotkb:sgg(gene name)|psi-mi:sgg(display_short)|uniprotkb:zw3(gene name synonym)|uniprotkb:CG2621(orf name)|uniprotkb:Protein zeste-white 3(gene name synonym)|uniprotkb:gsk3(gene name synonym) psi-mi:q961b0_drome(display_long)|uniprotkb:Apc2(gene name)|psi-mi:Apc2(display_short)|uniprotkb:CG6193(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871330 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476714.1|refseq:NP_476715.1|refseq:NP_476716.2|refseq:NP_599105.1|refseq:NP_726822.1|refseq:NP_726823.1|refseq:NP_996335.1|refseq:NP_996336.1|refseq:NP_996337.1|refseq:NP_996338.1|flybase:FBgn0003371|dip:DIP-39170N|ensemblmetazoa:FBgn0003371(gene)|ensemblmetazoa:FBtr0070466(transcript)|ensemblmetazoa:FBtr0070468(transcript)|ensemblmetazoa:FBtr0070469(transcript)|ensemblmetazoa:FBtr0070470(transcript)|ensemblmetazoa:FBtr0070472(transcript)|ensemblmetazoa:FBtr0070473(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007165"(signal transduction)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007507"(heart development)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008355"(olfactory learning)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0022416"(chaeta development)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030424"(axon)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035324"(female germline ring canal)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045169"(fusome)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046959"(habituation)|go:"GO:0048477"(oogenesis)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070884"(regulation of calcineurin-NFAT signaling cascade)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209387|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3371453|reactome:R-DME-399956|reactome:R-DME-432553|reactome:R-DME-4641262|reactome:R-DME-5610785 flybase:FBgn0026598|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001708"(cell fate specification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008362"(chitin-based embryonic cuticle biosynthetic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035190"(syncytial nuclear migration)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045180"(basal cortex)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009240(APC 15 residue)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR041257 pubmed:11584277(see-also)|pubmed:10559900(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:sUjAtUAobW55mTZBsRiQg0K1U9o7227 rogid:af4z/XtsifloaMOVwVH60lHxyNI7227 intact-crc:946F2735DE7531B3|rigid:rmhtKt9VInkRiSlzvUByAlA6Qmg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9V407 uniprotkb:Q961B0 intact:EBI-196300|uniprotkb:Q9XYC1|ensemblmetazoa:FBpp0084919|ensemblmetazoa:FBpp0084921 intact:EBI-867895 psi-mi:axn_drome(display_long)|uniprotkb:Axn(gene name)|psi-mi:Axn(display_short)|uniprotkb:CG7926(orf name)|uniprotkb:Axis inhibition protein(gene name synonym)|uniprotkb:d-Axin(gene name synonym) psi-mi:q961b0_drome(display_long)|uniprotkb:Apc2(gene name)|psi-mi:Apc2(display_short)|uniprotkb:CG6193(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871334 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_733336.1|refseq:NP_733337.1|flybase:FBgn0026597|dip:DIP-20929N|ensemblmetazoa:FBgn0026597(gene)|ensemblmetazoa:FBtr0085553(transcript)|ensemblmetazoa:FBtr0085555(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0042594"(response to starvation)|go:"GO:0048477"(oogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-209155|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-432553|reactome:R-DME-4641257|reactome:R-DME-4641262|reactome:R-DME-5689880 flybase:FBgn0026598|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001708"(cell fate specification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008362"(chitin-based embryonic cuticle biosynthetic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035190"(syncytial nuclear migration)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045180"(basal cortex)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009240(APC 15 residue)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR041257 pubmed:10526234(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:DLh/oPS70AHp3EC8ZZOspfCGrLA7227 rogid:af4z/XtsifloaMOVwVH60lHxyNI7227 intact-crc:29FFEE53406A36EF|rigid:FWZFnW6IIaRvt+8zhZ6vL1daUzQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18824 uniprotkb:Q961B0 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 intact:EBI-867895 psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:q961b0_drome(display_long)|uniprotkb:Apc2(gene name)|psi-mi:Apc2(display_short)|uniprotkb:CG6193(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871338 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 flybase:FBgn0026598|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001708"(cell fate specification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008362"(chitin-based embryonic cuticle biosynthetic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035190"(syncytial nuclear migration)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045180"(basal cortex)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009240(APC 15 residue)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR041257 pubmed:11584277(see-also)|pubmed:10526234(see-also)|pubmed:10559900(see-also)|pubmed:10491393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 rogid:af4z/XtsifloaMOVwVH60lHxyNI7227 intact-crc:5E38BB300EF2C7F3|rigid:WxMMc4niOhSfY+18T05eT1kk5m4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O96782 uniprotkb:A1Z9X0 intact:EBI-867941 intact:EBI-160861|ensemblmetazoa:FBpp0292487|ensemblmetazoa:FBpp0292491|intact:EBI-2296820|intact:EBI-867915|intact:EBI-2027110|intact:EBI-2656028|uniprotkb:Q0E971|uniprotkb:Q0E972|uniprotkb:Q0E973|uniprotkb:Q0E974|uniprotkb:Q8MT38|uniprotkb:Q9GSZ3 psi-mi:o96782_drome(display_long)|uniprotkb:baz(gene name)|psi-mi:baz(display_short)|uniprotkb:bazooka(gene name synonym)|uniprotkb:CG5055(orf name) psi-mi:apkc_drome(display_long)|uniprotkb:aPKC(gene name)|psi-mi:aPKC(display_short)|uniprotkb:CG30475(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871342 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0000163|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005912"(adherens junction)|go:"GO:0005914"(spot adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007299"(ovarian follicle cell-cell adhesion)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007377"(germ-band extension)|go:"GO:0007416"(synapse assembly)|go:"GO:0008104"(protein localization)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030709"(border follicle cell delamination)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0072002"(Malpighian tubule development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:O96782 refseq:NP_001036541.1|refseq:NP_524892.2|flybase:FBgn0261854|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045176"(apical protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045196"(establishment or maintenance of neuroblast polarity)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046872"(metal ion binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051601"(exocyst localization)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140591"(nuclear envelope budding)|go:"GO:1904580"(regulation of intracellular mRNA localization)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012233(Protein kinase C, zeta/iota)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0035331"(negative regulation of hippo signaling)|ensemblmetazoa:FBgn0261854(gene)|ensemblmetazoa:FBtr0303430(transcript)|ensemblmetazoa:FBtr0303434(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007416"(synapse assembly)|go:"GO:0007423"(sensory organ development)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007613"(memory)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016332"(establishment or maintenance of polarity of embryonic epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0017022"(myosin binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030860"(regulation of polarized epithelial cell differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0035003"(subapical complex)|go:"GO:0035011"(melanotic encapsulation of foreign target)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034659|interpro:IPR034877|reactome:R-DME-2173791|reactome:R-DME-5218921|reactome:R-DME-9634635|refseq:NP_001036542.1|refseq:NP_001036543.1|refseq:NP_001036544.1|refseq:NP_001036545.1 pubmed:10995441(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:UT2HtbwNRFuGCQL1dHzbkIBnJe47227 rogid:w7Lc8l4/50NKAWamwS+Lzk6lbgA7227 intact-crc:C493258BBC669177|rigid:dltBqySbbhpcY2BX4OnW8o29/6s false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8MT00 uniprotkb:O16114 intact:EBI-498544 intact:EBI-300304 psi-mi:q8mt00_drome(display_long)|uniprotkb:mbf1(gene name)|psi-mi:mbf1(display_short)|uniprotkb:CG4143(orf name) psi-mi:o16114_drome(display_long)|uniprotkb:apt(gene name)|psi-mi:apt(display_short)|uniprotkb:CG5393(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871346 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0262732|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007417"(central nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II) go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007319"(negative regulation of oskar mRNA translation)|go:"GO:0007417"(central nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048149"(behavioral response to ethanol)|interpro:IPR028002|flybase:FBgn0015903 pubmed:12506002(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:HrB2Wr/u8piXH/mJkKBnWMPsl3E7227 rogid:qx1kUi9kN+ebS/0V6JNki0xX5JM7227 intact-crc:A1BD8BF096641ED8|rigid:9uLjlgsub2XB2emu61Zj5XSk7+k false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9NBC8 uniprotkb:Q9VC44 intact:EBI-129247|uniprotkb:Q9VAU0|ensemblmetazoa:FBpp0084685|ensemblmetazoa:FBpp0307766 intact:EBI-176622|uniprotkb:Q9NB67|ensemblmetazoa:FBpp0084119|ensemblmetazoa:FBpp0312068 psi-mi:q9nbc8_drome(display_long)|uniprotkb:AstA-R2(gene name)|psi-mi:AstA-R2(display_short)|uniprotkb:AR-2(gene name synonym)|uniprotkb:ASTR(gene name synonym)|uniprotkb:D.AlstR2(gene name synonym)|uniprotkb:DAR(gene name synonym)|uniprotkb:DAR-2(gene name synonym)|uniprotkb:DAR2(gene name synonym)|uniprotkb:Dar-2(gene name synonym)|uniprotkb:Dmel\CG10001(gene name synonym)|uniprotkb:anon-WO0131005.7(gene name synonym)|uniprotkb:anon-WO0170980.115(gene name synonym)|uniprotkb:anon-WO0170980.116(gene name synonym)|uniprotkb:Dmel_CG10001(orf name)|uniprotkb:CG10001(orf name)|uniprotkb:Dar2(gene name synonym) psi-mi:alls_drome(display_long)|uniprotkb:AstA(gene name)|psi-mi:AstA(display_short)|uniprotkb:Allatostatins Ast(gene name synonym)|uniprotkb:Ast(gene name synonym)|uniprotkb:CG13633(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871350 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524544.1|flybase:FBgn0039595|ensemblmetazoa:FBgn0039595(gene)|ensemblmetazoa:FBtr0085316(transcript)|ensemblmetazoa:FBtr0336790(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004983"(neuropeptide Y receptor activity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008188"(neuropeptide receptor activity)|go:"GO:0008261"(allatostatin receptor activity)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000611(Neuropeptide Y receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-DME-391906|reactome:R-DME-416476|reactome:R-DME-418555|reactome:R-DME-6798695|go:"GO:0005887"(integral component of plasma membrane)|refseq:NP_001263042.1 refseq:NP_524489.2|flybase:FBgn0015591|refseq:NP_001287511.1|ensemblmetazoa:FBgn0015591(gene)|ensemblmetazoa:FBtr0084744(transcript)|ensemblmetazoa:FBtr0346367(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005184"(neuropeptide hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0045968"(negative regulation of juvenile hormone biosynthetic process)|go:"GO:0071855"(neuropeptide receptor binding)|interpro:IPR010276(Allatostatin) pubmed:11527415(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:bxLTIh1/UFVUe+lsXARUFNi3KBg7227 rogid:cHXHru6yHkwGyOEwZYU/t3HBgmw7227 intact-crc:872953687F8F13D4|rigid:zA3H+ZzbpqFtw5o9BSS6iK9R4r8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q08473 uniprotkb:O02374 intact:EBI-130500|uniprotkb:Q3ZAN7|uniprotkb:Q26273|uniprotkb:Q8IH71|uniprotkb:Q8INH1|uniprotkb:Q8MSY1|uniprotkb:Q9VFT5|uniprotkb:Q9VFT6|ensemblmetazoa:FBpp0082320 intact:EBI-850073 psi-mi:sqd_drome(display_long)|uniprotkb:sqd(gene name)|psi-mi:sqd(display_short)|uniprotkb:hrp40(gene name synonym)|uniprotkb:CG16901(orf name)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 40(gene name synonym) psi-mi:o02374_drome(display_long)|uniprotkb:bru1(gene name)|psi-mi:bru1(display_short)|uniprotkb:aret(gene name synonym)|uniprotkb:bruno(gene name synonym)|uniprotkb:CG31762(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871354 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_652209.1|refseq:NP_731825.1|refseq:NP_731826.1|refseq:NP_996203.1|refseq:NP_001247088.1|ensemblmetazoa:FBgn0263396(gene)|ensemblmetazoa:FBtr0082855(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0035062"(omega speckle)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0048477"(oogenesis)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-DME-450408|reactome:R-DME-72163|go:"GO:0005737"(cytoplasm)|flybase:FBgn0263396 flybase:FBgn0000114|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0007281"(germ cell development)|go:"GO:0007319"(negative regulation of oskar mRNA translation)|go:"GO:0014881"(regulation of myofibril size)|go:"GO:0016604"(nuclear body)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0043186"(P granule)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048477"(oogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034196|interpro:IPR035979 pubmed:10197986(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NfWBBjp/8+FNG6V/9i3khE0NbJs7227 rogid:zYXyOMb1ribCF1A3FVM/OlrOS/E7227 intact-crc:740239647A5AB262|rigid:Df3AjaKiLb3jIOK+LhWTYwGtGA0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P04412 uniprotkb:Q00805 intact:EBI-197863|uniprotkb:O18370|uniprotkb:O61601|uniprotkb:P81868|uniprotkb:Q9W2G0|ensemblmetazoa:FBpp0071571 intact:EBI-596393|uniprotkb:Q8MQZ2|uniprotkb:Q9VV64|ensemblmetazoa:FBpp0075166 psi-mi:egfr_drome(display_long)|uniprotkb:Egfr(gene name)|psi-mi:Egfr(display_short)|uniprotkb:top(gene name synonym)|uniprotkb:DER(gene name synonym)|uniprotkb:c-erbB(gene name synonym)|uniprotkb:CG10079(orf name)|uniprotkb:Gurken receptor(gene name synonym)|uniprotkb:Protein torpedo(gene name synonym)|uniprotkb:Drosophila relative of ERBB(gene name synonym) psi-mi:gil_drome(display_long)|uniprotkb:Protein argos(gene name synonym)|uniprotkb:Protein strawberry(gene name synonym)|uniprotkb:aos(gene name)|psi-mi:aos(display_short)|uniprotkb:gil(gene name synonym)|uniprotkb:sty(gene name synonym)|uniprotkb:CG4531(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871358 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476759.1|flybase:FBgn0003731|dip:DIP-17316N|ensemblmetazoa:FBgn0003731(gene)|ensemblmetazoa:FBtr0071654(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003015"(heart process)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007431"(salivary gland development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007477"(notum development)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007482"(haltere development)|go:"GO:0008071"(maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008355"(olfactory learning)|go:"GO:0008406"(gonad development)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0022008"(neurogenesis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035310"(notum cell fate specification)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|mint:P04412|rcsb pdb:3I2T|rcsb pdb:3LTF|rcsb pdb:3LTG|reactome:R-DME-1227986|reactome:R-DME-1250196|reactome:R-DME-1251985|reactome:R-DME-1253288|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-177929|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-1963642|reactome:R-DME-212718|reactome:R-DME-2179392|reactome:R-DME-416572|reactome:R-DME-5673001|reactome:R-DME-6785631|reactome:R-DME-6811558|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-9018519|reactome:R-DME-9652282 refseq:NP_524107.2|flybase:FBgn0004569|dip:DIP-60630N|ensemblmetazoa:FBgn0004569(gene)|ensemblmetazoa:FBtr0075408(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007601"(visual perception)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035215"(genital disc development)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050896"(response to stimulus)|go:"GO:0060233"(oenocyte delamination)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR021633|rcsb pdb:3C9A|rcsb pdb:3CGU pubmed:10688656(see-also)|pubmed:10918615(see-also)|pubmed:9461626(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Ae9kedh1v+TZ5zG4QorNPm9/FgA7227 rogid:aydIK44+0WVEAC0I/benId7LOnQ7227 intact-crc:FADD60B2101F9B51|rigid:5uwdrJyysMV4Pv3fiq9d8MBxSD0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7K738 uniprotkb:Q94981 intact:EBI-183920|ensemblmetazoa:FBpp0088522 intact:EBI-98607|uniprotkb:Q0KHQ9|ensemblmetazoa:FBpp0088499|ensemblmetazoa:FBpp0088500|ensemblmetazoa:FBpp0089023|ensemblmetazoa:FBpp0297199|ensemblmetazoa:FBpp0305073|ensemblmetazoa:FBpp0305074 psi-mi:ubc10_drome(display_long)|uniprotkb:Ubiquitin conjugating enzyme 10(gene name synonym)|uniprotkb:Ubc10(gene name)|psi-mi:Ubc10(display_short)|uniprotkb:ubcD10(gene name synonym)|uniprotkb:CG5788(orf name) psi-mi:ari1_drome(display_long)|uniprotkb:ari-1(gene name)|psi-mi:ari-1(display_short)|uniprotkb:ari(gene name synonym)|uniprotkb:Protein ariadne-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ariadne-1(gene name synonym)|uniprotkb:ari-1a(gene name synonym)|uniprotkb:CG5659(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871362 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477414.1|flybase:FBgn0026316|ensemblmetazoa:FBgn0026316(gene)|ensemblmetazoa:FBtr0089553(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0097039"(protein linear polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-1169408|reactome:R-DME-8866652|reactome:R-DME-983168 refseq:NP_523399.1|refseq:NP_728145.1|refseq:NP_996500.1|flybase:FBgn0017418|refseq:NP_001259671.1|refseq:NP_001259672.1|refseq:NP_001245736.1|ensemblmetazoa:FBgn0017418(gene)|ensemblmetazoa:FBtr0089506(transcript)|ensemblmetazoa:FBtr0089507(transcript)|ensemblmetazoa:FBtr0089508(transcript)|ensemblmetazoa:FBtr0306057(transcript)|ensemblmetazoa:FBtr0332850(transcript)|ensemblmetazoa:FBtr0332851(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048477"(oogenesis)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|interpro:IPR031127|interpro:IPR044066|reactome:R-DME-1169408|dip:DIP-17812N pubmed:10880484(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:TrJOtp74RGZ/4GoqiszRn9X7jOo7227 rogid:cBRqZL0/B/6FkvFO3d44W3oZBck7227 intact-crc:46541A8B56F77C5B|rigid:+qTCHPJQ0K5rD4TT1Q4pPoMooB0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8IRY7 uniprotkb:Q9U8R4 intact:EBI-442182|ensemblmetazoa:FBpp0113052|uniprotkb:O02433|uniprotkb:O76797|uniprotkb:O76798|uniprotkb:Q95T94|uniprotkb:Q9UB42|uniprotkb:Q9W5E3 intact:EBI-93302|ensemblmetazoa:FBpp0086121 psi-mi:casp8_drome(display_long)|uniprotkb:Death-related ced-3/NEDD2-like protein(gene name synonym)|uniprotkb:Dredd(gene name)|psi-mi:Dredd(display_short)|uniprotkb:DCP2(gene name synonym)|uniprotkb:CG7486(orf name) psi-mi:q9u8r4_drome(display_long)|uniprotkb:Dark(gene name)|psi-mi:Dark(display_short)|uniprotkb:Ark(gene name synonym)|uniprotkb:dapaf-1S(gene name synonym)|uniprotkb:APAF-1(gene name synonym)|uniprotkb:APAF1(gene name synonym)|uniprotkb:ARK(gene name synonym)|uniprotkb:Apaf(gene name synonym)|uniprotkb:Apaf-1(gene name synonym)|uniprotkb:Apaf-I(gene name synonym)|uniprotkb:Apaf1(gene name synonym)|uniprotkb:D-Apaf-1(gene name synonym)|uniprotkb:DARK(gene name synonym)|uniprotkb:Dapaf-1(gene name synonym)|uniprotkb:Dmel\CG6829(gene name synonym)|uniprotkb:HAC-1(gene name synonym)|uniprotkb:HAC1(gene name synonym)|uniprotkb:Hac-1(gene name synonym)|uniprotkb:Hac1(gene name synonym)|uniprotkb:T1(gene name synonym)|uniprotkb:anon-53Fa(gene name synonym)|uniprotkb:apaf-1(gene name synonym)|uniprotkb:apaf1(gene name synonym)|uniprotkb:arc(gene name synonym)|uniprotkb:ark(gene name synonym)|uniprotkb:dAPAF-1(gene name synonym)|uniprotkb:dApaf-1(gene name synonym)|uniprotkb:dApaf1(gene name synonym)|uniprotkb:dArk(gene name synonym)|uniprotkb:dapaf(gene name synonym)|uniprotkb:dapaf-1(gene name synonym)|uniprotkb:dapaf-1L(gene name synonym)|uniprotkb:dark(gene name synonym)|uniprotkb:hac-1(gene name synonym)|uniprotkb:hac1(gene name synonym)|uniprotkb:"l(2)SH0173"(gene name synonym)|uniprotkb:CG6829(orf name)|uniprotkb:Dmel_CG6829(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871366 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0020381(gene)|ensemblmetazoa:FBtr0114560(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0006955"(immune response)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0006964"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0007291"(sperm individualization)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0016485"(protein processing)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|reactome:R-DME-198323|reactome:R-DME-214397|reactome:R-DME-214399|reactome:R-DME-214411|reactome:R-DME-214416|reactome:R-DME-448706|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|flybase:FBgn0020381|refseq:NP_477249.3|refseq:NP_477250.3|refseq:NP_477251.3 refseq:NP_725638.1|flybase:FBgn0263864|go:"GO:0042594"(response to starvation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043531"(ADP binding)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:1901053"(sarcosine catabolic process)|interpro:IPR002182(NB-ARC)|interpro:IPR027417|interpro:IPR036388|go:"GO:0035071"(salivary gland cell autophagic cell death)|ensemblmetazoa:FBtr0086967(transcript)|go:"GO:0002921"(negative regulation of humoral immune response)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0012501"(programmed cell death)|go:"GO:0021556"(central nervous system formation)|go:"GO:0022416"(chaeta development)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0034352"(positive regulation of glial cell apoptotic process)|go:"GO:0035006"(melanization defense response)|go:"GO:0035070"(salivary gland histolysis)|ensemblmetazoa:FBgn0263864(gene) pubmed:10559939(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8VF2wS5q6ZXJbm/BlLH8aUFz9bw7227 rogid:YrqlXWeLXBhue+zBtCo0jMBeqmk7227 intact-crc:7BB90C1AD0FDBCC5|rigid:ZYvZOv0ntllAFjt7BdP0Pmy0WwY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9U8R4 uniprotkb:Q9U8R4 intact:EBI-93302|ensemblmetazoa:FBpp0086121 intact:EBI-93302|ensemblmetazoa:FBpp0086121 psi-mi:q9u8r4_drome(display_long)|uniprotkb:Dark(gene name)|psi-mi:Dark(display_short)|uniprotkb:Ark(gene name synonym)|uniprotkb:dapaf-1S(gene name synonym)|uniprotkb:APAF-1(gene name synonym)|uniprotkb:APAF1(gene name synonym)|uniprotkb:ARK(gene name synonym)|uniprotkb:Apaf(gene name synonym)|uniprotkb:Apaf-1(gene name synonym)|uniprotkb:Apaf-I(gene name synonym)|uniprotkb:Apaf1(gene name synonym)|uniprotkb:D-Apaf-1(gene name synonym)|uniprotkb:DARK(gene name synonym)|uniprotkb:Dapaf-1(gene name synonym)|uniprotkb:Dmel\CG6829(gene name synonym)|uniprotkb:HAC-1(gene name synonym)|uniprotkb:HAC1(gene name synonym)|uniprotkb:Hac-1(gene name synonym)|uniprotkb:Hac1(gene name synonym)|uniprotkb:T1(gene name synonym)|uniprotkb:anon-53Fa(gene name synonym)|uniprotkb:apaf-1(gene name synonym)|uniprotkb:apaf1(gene name synonym)|uniprotkb:arc(gene name synonym)|uniprotkb:ark(gene name synonym)|uniprotkb:dAPAF-1(gene name synonym)|uniprotkb:dApaf-1(gene name synonym)|uniprotkb:dApaf1(gene name synonym)|uniprotkb:dArk(gene name synonym)|uniprotkb:dapaf(gene name synonym)|uniprotkb:dapaf-1(gene name synonym)|uniprotkb:dapaf-1L(gene name synonym)|uniprotkb:dark(gene name synonym)|uniprotkb:hac-1(gene name synonym)|uniprotkb:hac1(gene name synonym)|uniprotkb:"l(2)SH0173"(gene name synonym)|uniprotkb:CG6829(orf name)|uniprotkb:Dmel_CG6829(orf name) psi-mi:q9u8r4_drome(display_long)|uniprotkb:Dark(gene name)|psi-mi:Dark(display_short)|uniprotkb:Ark(gene name synonym)|uniprotkb:dapaf-1S(gene name synonym)|uniprotkb:APAF-1(gene name synonym)|uniprotkb:APAF1(gene name synonym)|uniprotkb:ARK(gene name synonym)|uniprotkb:Apaf(gene name synonym)|uniprotkb:Apaf-1(gene name synonym)|uniprotkb:Apaf-I(gene name synonym)|uniprotkb:Apaf1(gene name synonym)|uniprotkb:D-Apaf-1(gene name synonym)|uniprotkb:DARK(gene name synonym)|uniprotkb:Dapaf-1(gene name synonym)|uniprotkb:Dmel\CG6829(gene name synonym)|uniprotkb:HAC-1(gene name synonym)|uniprotkb:HAC1(gene name synonym)|uniprotkb:Hac-1(gene name synonym)|uniprotkb:Hac1(gene name synonym)|uniprotkb:T1(gene name synonym)|uniprotkb:anon-53Fa(gene name synonym)|uniprotkb:apaf-1(gene name synonym)|uniprotkb:apaf1(gene name synonym)|uniprotkb:arc(gene name synonym)|uniprotkb:ark(gene name synonym)|uniprotkb:dAPAF-1(gene name synonym)|uniprotkb:dApaf-1(gene name synonym)|uniprotkb:dApaf1(gene name synonym)|uniprotkb:dArk(gene name synonym)|uniprotkb:dapaf(gene name synonym)|uniprotkb:dapaf-1(gene name synonym)|uniprotkb:dapaf-1L(gene name synonym)|uniprotkb:dark(gene name synonym)|uniprotkb:hac-1(gene name synonym)|uniprotkb:hac1(gene name synonym)|uniprotkb:"l(2)SH0173"(gene name synonym)|uniprotkb:CG6829(orf name)|uniprotkb:Dmel_CG6829(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871370 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_725638.1|flybase:FBgn0263864|go:"GO:0042594"(response to starvation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043531"(ADP binding)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:1901053"(sarcosine catabolic process)|interpro:IPR002182(NB-ARC)|interpro:IPR027417|interpro:IPR036388|go:"GO:0035071"(salivary gland cell autophagic cell death)|ensemblmetazoa:FBtr0086967(transcript)|go:"GO:0002921"(negative regulation of humoral immune response)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0012501"(programmed cell death)|go:"GO:0021556"(central nervous system formation)|go:"GO:0022416"(chaeta development)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0034352"(positive regulation of glial cell apoptotic process)|go:"GO:0035006"(melanization defense response)|go:"GO:0035070"(salivary gland histolysis)|ensemblmetazoa:FBgn0263864(gene) refseq:NP_725638.1|flybase:FBgn0263864|go:"GO:0042594"(response to starvation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043531"(ADP binding)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:1901053"(sarcosine catabolic process)|interpro:IPR002182(NB-ARC)|interpro:IPR027417|interpro:IPR036388|go:"GO:0035071"(salivary gland cell autophagic cell death)|ensemblmetazoa:FBtr0086967(transcript)|go:"GO:0002921"(negative regulation of humoral immune response)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0012501"(programmed cell death)|go:"GO:0021556"(central nervous system formation)|go:"GO:0022416"(chaeta development)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0034352"(positive regulation of glial cell apoptotic process)|go:"GO:0035006"(melanization defense response)|go:"GO:0035070"(salivary gland histolysis)|ensemblmetazoa:FBgn0263864(gene) pubmed:7823930(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:YrqlXWeLXBhue+zBtCo0jMBeqmk7227 rogid:YrqlXWeLXBhue+zBtCo0jMBeqmk7227 intact-crc:B3D09077245695E0|rigid:vuvpnvWiyF0sDrWzXPUEZPfe99Q false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P22265 uniprotkb:P18824 intact:EBI-167288|uniprotkb:A8E6H0|uniprotkb:Q6AWP7|uniprotkb:Q7KRS3|uniprotkb:Q9V9Q0|ensemblmetazoa:FBpp0085261 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 psi-mi:tsh_drome(display_long)|uniprotkb:tsh(gene name)|psi-mi:tsh(display_short)|uniprotkb:CG1374(orf name) psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871374 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0003866(gene)|ensemblmetazoa:FBtr0085906(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007380"(specification of segmental identity, head)|go:"GO:0007384"(specification of segmental identity, thorax)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007473"(wing disc proximal/distal pattern formation)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007494"(midgut development)|go:"GO:0008258"(head involution)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035292"(specification of segmental identity, trunk)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0005654"(nucleoplasm)|flybase:FBgn0003866|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0061330"(Malpighian tubule stellate cell differentiation)|go:"GO:2000497"(positive regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR026807|interpro:IPR027008|interpro:IPR036236|interpro:IPR041661|reactome:R-DME-390193|refseq:NP_523615.2 refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 pubmed:10205174(see-also)|pubmed:9707400(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:4q9w9M/oqAa0jnzgXlKqVts2PBQ7227 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 intact-crc:FA72084282BD91D6|rigid:6ICC3jcgcyNQqiajFa6FSGeUTGE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24298 uniprotkb:P18824 intact:EBI-112930|uniprotkb:Q9W2N1|ensemblmetazoa:FBpp0071475 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 psi-mi:cade_drome(display_long)|uniprotkb:shg(gene name)|psi-mi:shg(display_short)|uniprotkb:Protein shotgun(gene name synonym)|uniprotkb:CG3722(orf name)|uniprotkb:E-cadherin(gene name synonym) psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871378 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476722.1|flybase:FBgn0003391|dip:DIP-22198N|ensemblmetazoa:FBgn0003391(gene)|ensemblmetazoa:FBtr0071546(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001748"(insect visual primordium development)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005914"(spot adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007281"(germ cell development)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007379"(segment specification)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008258"(head involution)|go:"GO:0008354"(germ cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008406"(gonad development)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0017022"(myosin binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043296"(apical junction complex)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045176"(apical protein localization)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0048477"(oogenesis)|go:"GO:0050832"(defense response to fungus)|go:"GO:0055037"(recycling endosome)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098730"(male germline stem cell symmetric division)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397 refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 pubmed:7958432(see-also)|pubmed:9112438(see-also)|pubmed:8794868(see-also)|pubmed:8943306(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:BEKC07n+twCk47JtwWbhQbw1cs87227 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 intact-crc:4E5E18DE1C5A9950|rigid:wawWsGRHVVnaaAyRXFkvKOauvjM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18431 uniprotkb:P18824 intact:EBI-242141|uniprotkb:O76881|uniprotkb:P23646|uniprotkb:Q27603|uniprotkb:Q27604|uniprotkb:Q27605|uniprotkb:Q8MRF7|uniprotkb:Q9NF42|uniprotkb:Q9U094|uniprotkb:Q9W4X3|ensemblmetazoa:FBpp0070449|ensemblmetazoa:FBpp0070451|ensemblmetazoa:FBpp0070452|ensemblmetazoa:FBpp0070453|ensemblmetazoa:FBpp0089158|ensemblmetazoa:FBpp0089162 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 psi-mi:sgg_drome(display_long)|uniprotkb:sgg(gene name)|psi-mi:sgg(display_short)|uniprotkb:zw3(gene name synonym)|uniprotkb:CG2621(orf name)|uniprotkb:Protein zeste-white 3(gene name synonym)|uniprotkb:gsk3(gene name synonym) psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871382 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476714.1|refseq:NP_476715.1|refseq:NP_476716.2|refseq:NP_599105.1|refseq:NP_726822.1|refseq:NP_726823.1|refseq:NP_996335.1|refseq:NP_996336.1|refseq:NP_996337.1|refseq:NP_996338.1|flybase:FBgn0003371|dip:DIP-39170N|ensemblmetazoa:FBgn0003371(gene)|ensemblmetazoa:FBtr0070466(transcript)|ensemblmetazoa:FBtr0070468(transcript)|ensemblmetazoa:FBtr0070469(transcript)|ensemblmetazoa:FBtr0070470(transcript)|ensemblmetazoa:FBtr0070472(transcript)|ensemblmetazoa:FBtr0070473(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007165"(signal transduction)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007507"(heart development)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008355"(olfactory learning)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0022416"(chaeta development)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030424"(axon)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035324"(female germline ring canal)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045169"(fusome)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046959"(habituation)|go:"GO:0048477"(oogenesis)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070884"(regulation of calcineurin-NFAT signaling cascade)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209387|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3371453|reactome:R-DME-399956|reactome:R-DME-432553|reactome:R-DME-4641262|reactome:R-DME-5610785 refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 pubmed:7529201(see-also)|pubmed:10419494(see-also)|pubmed:14966281(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:sUjAtUAobW55mTZBsRiQg0K1U9o7227 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 intact-crc:773E74BA2F158D7C|rigid:rVBwJUTMbSy28HyZ3hpn1YOW2ko false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9V3K3 uniprotkb:P18824 intact:EBI-192924|ensemblmetazoa:FBpp0074756|ensemblmetazoa:FBpp0304236|ensemblmetazoa:FBpp0311247 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 psi-mi:ruvb2_drome(display_long)|uniprotkb:rept(gene name)|psi-mi:rept(display_short)|uniprotkb:CG9750(orf name)|uniprotkb:Dreptin(gene name synonym)|uniprotkb:Reptin(gene name synonym) psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871386 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524156.1|flybase:FBgn0040075|refseq:NP_001287113.1|refseq:NP_001262040.1|ensemblmetazoa:FBgn0040075(gene)|ensemblmetazoa:FBtr0074988(transcript)|ensemblmetazoa:FBtr0331852(transcript)|ensemblmetazoa:FBtr0344993(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487 refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 pubmed:11080158(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:OTelAlg6zQwi3chtx0C/iDKL/607227 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 intact-crc:D4D0FB1663A048B2|rigid:DK01FyN41uEL63Q6ww12w8+9YRE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9V9W8 uniprotkb:P18824 intact:EBI-152653|ensemblmetazoa:FBpp0085167 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 psi-mi:pygo_drome(display_long)|uniprotkb:pygo(gene name)|psi-mi:pygo(display_short)|uniprotkb:gam(gene name synonym)|uniprotkb:CG11518(orf name)|uniprotkb:Protein gammy legs(gene name synonym) psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871390 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651872.1|flybase:FBgn0043900|ensemblmetazoa:FBgn0043900(gene)|ensemblmetazoa:FBtr0085806(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|rcsb pdb:3ZPV|reactome:R-DME-201722|reactome:R-DME-209407|reactome:R-DME-209421|dip:DIP-29989N refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 pubmed:12015286(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Vg/PibxqoE0VAobzkEW0yTD6hSg7227 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 intact-crc:F91A8FBC94BDB33E|rigid:SVZyr/In/BRFPWyQab3uGjorpfc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VH07 uniprotkb:P18824 intact:EBI-234957|intact:EBI-867973|uniprotkb:Q9VH06|uniprotkb:Q9NH53|intact:EBI-234969|ensemblmetazoa:FBpp0081704 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 psi-mi:ruvb1_drome(display_long)|uniprotkb:pont(gene name)|psi-mi:pont(display_short)|uniprotkb:CG4003(orf name)|uniprotkb:Pontin(gene name synonym)|uniprotkb:Dpontin(gene name synonym) psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871394 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_652608.1|flybase:FBgn0040078|ensemblmetazoa:FBgn0040078(gene)|ensemblmetazoa:FBtr0082226(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035060"(brahma complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051301"(cell division)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9VH07|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-5696394 refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 pubmed:11080158(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:myRpAnG8tKBHMEnKg+JkpIVkTKg7227 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 intact-crc:3A6DB9FD09FDA431|rigid:eSABAS22gDlN60675rAwFQq6P94 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P91943 uniprotkb:P18824 intact:EBI-147301|uniprotkb:O02548|uniprotkb:Q0KIE9|intact:EBI-1629313|uniprotkb:Q59DP5|uniprotkb:Q5BHZ3|uniprotkb:Q6W492|uniprotkb:Q6W493|uniprotkb:Q6W494|uniprotkb:Q6W495|uniprotkb:Q6W4A6|uniprotkb:Q6W4B4|uniprotkb:Q9V4B0|uniprotkb:A0AVW4|uniprotkb:A4V148|uniprotkb:B5RJS3|ensemblmetazoa:FBpp0088226|ensemblmetazoa:FBpp0088228|ensemblmetazoa:FBpp0088229|ensemblmetazoa:FBpp0301556 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 psi-mi:pang1_drome(display_long)|uniprotkb:pan(gene name)|psi-mi:pan(display_short)|uniprotkb:TCF(gene name synonym)|uniprotkb:dTCF(gene name synonym)|uniprotkb:CG34403(orf name) psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871398 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245406.1|refseq:NP_001014685.1|refseq:NP_001033798.1|refseq:NP_524619.3|refseq:NP_726522.1|refseq:NP_726524.1|flybase:FBgn0085432|refseq:NP_726527.2|dip:DIP-19970N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019900"(kinase binding)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR028782|interpro:IPR036910|reactome:R-DME-209421|reactome:R-DME-209441|ensemblmetazoa:FBgn0085432(gene)|ensemblmetazoa:FBtr0089159(transcript)|ensemblmetazoa:FBtr0089161(transcript)|ensemblmetazoa:FBtr0089162(transcript)|ensemblmetazoa:FBtr0309803(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific) refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 pubmed:9039917(see-also)|pubmed:9118222(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:H6BhYVP6spDgW8etHP7+/L29jO87227 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 intact-crc:1A7517600614051D|rigid:PMFzEaLzg6nhe4n96nqR93EGEDs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q961D9 uniprotkb:P18824 intact:EBI-85519|uniprotkb:Q9V4D2|ensemblmetazoa:FBpp0088180 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 psi-mi:bcl9_drome(display_long)|uniprotkb:lgs(gene name)|psi-mi:lgs(display_short)|uniprotkb:BCL9(gene name synonym)|uniprotkb:CG2041(orf name)|uniprotkb:Protein legless(gene name synonym) psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871402 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651922.1|flybase:FBgn0039907|ensemblmetazoa:FBgn0039907(gene)|ensemblmetazoa:FBtr0089111(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007491"(sternite morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0035223"(leg disc pattern formation)|rcsb pdb:3ZPV|reactome:R-DME-201722|reactome:R-DME-209407|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|reactome:R-DME-209421|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR024670|dip:DIP-33392N refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 pubmed:15294866(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:W5+IVXO6J6D9E9N7P5R6tFQ7bpc7227 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 intact-crc:A539DD30CE562041|rigid:dND5TwXtBut8BEt9xmrTFagEzcc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P54367 uniprotkb:P18824 intact:EBI-129996|uniprotkb:A4V4D3|uniprotkb:Q0KHT2|uniprotkb:Q9VYK2|ensemblmetazoa:FBpp0073513|ensemblmetazoa:FBpp0073515|ensemblmetazoa:FBpp0289609|ensemblmetazoa:FBpp0309354|ensemblmetazoa:FBpp0311372|ensemblmetazoa:FBpp0311373 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 psi-mi:kc1a_drome(display_long)|uniprotkb:CkIalpha(gene name)|psi-mi:CkIalpha(display_short)|uniprotkb:CKI(gene name synonym)|uniprotkb:CG2028(orf name) psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871406 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162737.1|refseq:NP_511140.1|refseq:NP_727631.1|refseq:NP_727632.1|flybase:FBgn0015024|ensemblmetazoa:FBtr0073680(transcript)|ensemblmetazoa:FBtr0073682(transcript)|ensemblmetazoa:FBtr0300380(transcript)|ensemblmetazoa:FBtr0340408(transcript)|ensemblmetazoa:FBtr0345162(transcript)|ensemblmetazoa:FBtr0345163(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-432553|reactome:R-DME-5610785|reactome:R-DME-5635838|refseq:NP_001285163.1|refseq:NP_001285164.1|ensemblmetazoa:FBgn0015024(gene)|dip:DIP-22041N refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 pubmed:11927557(see-also)|pubmed:14966281(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Ze6yIkD2EQvC/BIhGbjP6MoS8aI7227 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 intact-crc:3A6CAE610E290A2A|rigid:jbCvBF0RAJ0sW7Y37e2fK+9xUbQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q4V6B6 uniprotkb:P18824 intact:EBI-867987|uniprotkb:Q9VD70|ensemblmetazoa:FBpp0312613 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 psi-mi:q4v6b6_drome(display_long)|uniprotkb:CG13415(gene name)|psi-mi:CG13415(display_short) psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871410 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028118|ensemblmetazoa:FBgn0067317(gene)|ensemblmetazoa:FBtr0347600(transcript)|go:"GO:0005930"(axoneme)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0048060"(negative gravitaxis)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound) refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 pubmed:12712206(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:BALU7U6Tr28XBlA0jNj/0eqsyho7227 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 intact-crc:EE3101E9610B0000|rigid:IwuOFODh3Qtfdz/KsorYAXx/msY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9V407 uniprotkb:P18824 intact:EBI-196300|uniprotkb:Q9XYC1|ensemblmetazoa:FBpp0084919|ensemblmetazoa:FBpp0084921 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 psi-mi:axn_drome(display_long)|uniprotkb:Axn(gene name)|psi-mi:Axn(display_short)|uniprotkb:CG7926(orf name)|uniprotkb:Axis inhibition protein(gene name synonym)|uniprotkb:d-Axin(gene name synonym) psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871414 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_733336.1|refseq:NP_733337.1|flybase:FBgn0026597|dip:DIP-20929N|ensemblmetazoa:FBgn0026597(gene)|ensemblmetazoa:FBtr0085553(transcript)|ensemblmetazoa:FBtr0085555(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0042594"(response to starvation)|go:"GO:0048477"(oogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-209155|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-432553|reactome:R-DME-4641257|reactome:R-DME-4641262|reactome:R-DME-5689880 refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 pubmed:10419494(see-also)|pubmed:10838083(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:DLh/oPS70AHp3EC8ZZOspfCGrLA7227 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 intact-crc:2997CC6109FA7914|rigid:JSkta3c7Mf8aI3dL8mVAdYHo27E false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P32392 uniprotkb:P45888 intact:EBI-176768|uniprotkb:Q9VSD5|uniprotkb:M9PEY5|ensemblmetazoa:FBpp0076460|ensemblmetazoa:FBpp0306212 intact:EBI-138385|uniprotkb:Q9VXF3|uniprotkb:A8JV17|uniprotkb:F0JAK9|ensemblmetazoa:FBpp0302793 psi-mi:arp3_drome(display_long)|uniprotkb:Actin-2(gene name synonym)|uniprotkb:Actin-like protein 3(gene name synonym)|uniprotkb:Actin-like protein 66B(gene name synonym)|uniprotkb:Actr66B(gene name synonym)|uniprotkb:Arp66B(gene name synonym)|uniprotkb:CG7558(orf name)|uniprotkb:Arp3(gene name)|psi-mi:Arp3(display_short) psi-mi:arp2_drome(display_long)|uniprotkb:Arp2(gene name)|psi-mi:Arp2(display_short)|uniprotkb:Actin-like protein 14D(gene name synonym)|uniprotkb:Actin-like protein 2(gene name synonym)|uniprotkb:Actr14D(gene name synonym)|uniprotkb:Arp14D(gene name synonym)|uniprotkb:CG9901(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871418 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523968.1|flybase:FBgn0262716|refseq:NP_001261559.1|dip:DIP-20563N|ensemblmetazoa:FBgn0262716(gene)|ensemblmetazoa:FBtr0076737(transcript)|ensemblmetazoa:FBtr0334087(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007520"(myoblast fusion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0022416"(chaeta development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030037"(actin filament reorganization involved in cell cycle)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0072553"(terminal button organization)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0140591"(nuclear envelope budding)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-5663213|reactome:R-DME-8856828 refseq:NP_001097001.1|refseq:NP_523372.2|flybase:FBgn0011742|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0007015"(actin filament organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0072553"(terminal button organization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|reactome:R-DME-2029482|reactome:R-DME-3928662|reactome:R-DME-5663213|reactome:R-DME-6798695|reactome:R-DME-8856828|refseq:NP_001259621.1|ensemblmetazoa:FBgn0011742(gene)|ensemblmetazoa:FBtr0310673(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament) pubmed:12007413(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:RbDFOKwIIlYyOCjn5pisIvxW+DA7227 rogid:xFG11cIs1RnyopRmisnJlyLqAd07227 intact-crc:F2E806BFD5A7FAAE|rigid:25j5eh7EBd3UrE57pxRiBpGyD4s false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P13496 uniprotkb:P45889 intact:EBI-157742|ensemblmetazoa:FBpp0075498|uniprotkb:Q9VUA1|uniprotkb:B5X0J0|uniprotkb:Q8MT52 intact:EBI-137955|uniprotkb:Q9VG37|ensemblmetazoa:FBpp0082121 psi-mi:dctn1_drome(display_long)|uniprotkb:DCTN1-p150(gene name)|psi-mi:DCTN1-p150(display_short)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:Dynactin 1 subunit p150(gene name synonym)|uniprotkb:Gl(gene name synonym)|uniprotkb:Protein glued(gene name synonym)|uniprotkb:CG9206(orf name) psi-mi:actz_drome(display_long)|uniprotkb:Arp1(gene name)|psi-mi:Arp1(display_short)|uniprotkb:Actin-like protein 1(gene name synonym)|uniprotkb:Actin-like protein 87C(gene name synonym)|uniprotkb:Actr87C(gene name synonym)|uniprotkb:Arp87C(gene name synonym)|uniprotkb:CG6174(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871422 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0001108(gene)|ensemblmetazoa:FBtr0075756(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0001709"(cell fate determination)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005818"(aster)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007097"(nuclear migration)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042052"(rhabdomere development)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048491"(retrograde synaptic vesicle transport)|go:"GO:0048675"(axon extension)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051225"(spindle assembly)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0051383"(kinetochore organization)|go:"GO:0051642"(centrosome localization)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0070840"(dynein complex binding)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|reactome:R-DME-3371497|reactome:R-DME-6807878|reactome:R-DME-6811436|go:"GO:0061670"(evoked neurotransmitter secretion)|refseq:NP_524061.1|flybase:FBgn0001108|dip:DIP-21099N refseq:NP_524331.2|flybase:FBgn0011745|dip:DIP-18643N|ensemblmetazoa:FBgn0011745(gene)|ensemblmetazoa:FBtr0082652(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005524"(ATP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-DME-3371497|reactome:R-DME-6798695|reactome:R-DME-6807878|reactome:R-DME-6811436 pubmed:12062020(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:B7uGKXFHteDp0TXcuFS3123n0xg7227 rogid:C8EG/m/Qv+6A0Sj6g+9iDQ/r8Wk7227 intact-crc:E9B414369B2AFF43|rigid:HIdqAukESw01oM6c6y4NRvngdOM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VVX3 uniprotkb:Q6AWJ8 intact:EBI-118222|uniprotkb:A8JNV7|uniprotkb:Q494J1|uniprotkb:Q94916|uniprotkb:Q9VVX2|intact:EBI-3433048|ensemblmetazoa:FBpp0074795|ensemblmetazoa:FBpp0074796|ensemblmetazoa:FBpp0111803|ensemblmetazoa:FBpp0288861|ensemblmetazoa:FBpp0303227|ensemblmetazoa:FBpp0304981 intact:EBI-867997|ensemblmetazoa:FBpp0086821 psi-mi:friz2_drome(display_long)|uniprotkb:CG9739(orf name)|uniprotkb:fz2(gene name)|psi-mi:fz2(display_short) psi-mi:q6awj8_drome(display_long)|uniprotkb:arr(gene name)|psi-mi:arr(display_short)|uniprotkb:CG5912(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871426 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001262036.1|refseq:NP_001262038.1|refseq:NP_001097643.1|refseq:NP_001137971.1|refseq:NP_524155.1|refseq:NP_730389.1|flybase:FBgn0016797|ensemblmetazoa:FBgn0016797(gene)|ensemblmetazoa:FBtr0075028(transcript)|ensemblmetazoa:FBtr0075029(transcript)|ensemblmetazoa:FBtr0112890(transcript)|ensemblmetazoa:FBtr0299586(transcript)|ensemblmetazoa:FBtr0330194(transcript)|ensemblmetazoa:FBtr0332735(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0042685"(cardioblast cell fate specification)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048675"(axon extension)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|reactome:R-DME-209387|reactome:R-DME-209440|reactome:R-DME-209472|reactome:R-DME-4086398|reactome:R-DME-4608870|reactome:R-DME-5140745|dip:DIP-17196N flybase:FBgn0000119|ensemblmetazoa:FBgn0000119(gene)|ensemblmetazoa:FBtr0087702(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0007616"(long-term memory)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0048076"(regulation of compound eye pigmentation)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like) pubmed:12205098(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:DONCeTs13fWZaew7Mv060K0qqjg7227 rogid:sV8LCiYRISruBhx/oqYqL9zOPYI7227 intact-crc:28FE849906A959C6|rigid:kgSvgY9AYRCA8Zgfn93+Q5/lpKI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9V407 uniprotkb:Q6AWJ8 intact:EBI-196300|uniprotkb:Q9XYC1|ensemblmetazoa:FBpp0084919|ensemblmetazoa:FBpp0084921 intact:EBI-867997|ensemblmetazoa:FBpp0086821 psi-mi:axn_drome(display_long)|uniprotkb:Axn(gene name)|psi-mi:Axn(display_short)|uniprotkb:CG7926(orf name)|uniprotkb:Axis inhibition protein(gene name synonym)|uniprotkb:d-Axin(gene name synonym) psi-mi:q6awj8_drome(display_long)|uniprotkb:arr(gene name)|psi-mi:arr(display_short)|uniprotkb:CG5912(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871430 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_733336.1|refseq:NP_733337.1|flybase:FBgn0026597|dip:DIP-20929N|ensemblmetazoa:FBgn0026597(gene)|ensemblmetazoa:FBtr0085553(transcript)|ensemblmetazoa:FBtr0085555(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0042594"(response to starvation)|go:"GO:0048477"(oogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-209155|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-432553|reactome:R-DME-4641257|reactome:R-DME-4641262|reactome:R-DME-5689880 flybase:FBgn0000119|ensemblmetazoa:FBgn0000119(gene)|ensemblmetazoa:FBtr0087702(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0007616"(long-term memory)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0048076"(regulation of compound eye pigmentation)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like) pubmed:12711303(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:DLh/oPS70AHp3EC8ZZOspfCGrLA7227 rogid:sV8LCiYRISruBhx/oqYqL9zOPYI7227 intact-crc:7E65C0FB6D6F4CE0|rigid:AM+xrtjOiHrCdkZwFsLFCBSPmzw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P06002 uniprotkb:P15372 intact:EBI-100064|uniprotkb:Q9TX56|ensemblmetazoa:FBpp0083266|uniprotkb:Q9VDS8|uniprotkb:A0AVV9|uniprotkb:Q4QPQ2 intact:EBI-145156|uniprotkb:Q9VJA8|ensemblmetazoa:FBpp0080583|ensemblmetazoa:FBpp0298351 psi-mi:ops1_drome(display_long)|uniprotkb:ninaE(gene name)|psi-mi:ninaE(display_short)|uniprotkb:Rh1(gene name synonym)|uniprotkb:CG4550(orf name)|uniprotkb:Outer R1-R6 photoreceptor cells opsin(gene name synonym)|uniprotkb:Neither inactivation nor afterpotential E protein(gene name synonym) psi-mi:arra_drome(display_long)|uniprotkb:Arr1(gene name)|psi-mi:Arr1(display_short)|uniprotkb:ArrA(gene name synonym)|uniprotkb:CG5711(orf name)|uniprotkb:Phosrestin II(gene name synonym)|uniprotkb:Arrestin-A(gene name synonym)|uniprotkb:Arrestin-1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871434 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524407.1|flybase:FBgn0002940|ensemblmetazoa:FBgn0002940(gene)|ensemblmetazoa:FBtr0083857(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005769"(early endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009584"(detection of visible light)|go:"GO:0009589"(detection of UV)|go:"GO:0009642"(response to light intensity)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0016029"(subrhabdomeral cisterna)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030265"(phospholipase C-activating rhodopsin mediated signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042331"(phototaxis)|go:"GO:0043052"(thermotaxis)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0071632"(optomotor response)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001735(Opsin RH1/RH2)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR027430|mint:P06002|dip:DIP-17500N refseq:NP_476681.1|flybase:FBgn0000120|refseq:NP_001246073.1|dip:DIP-19039N|ensemblmetazoa:FBgn0000120(gene)|ensemblmetazoa:FBtr0081030(transcript)|ensemblmetazoa:FBtr0307350(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002046"(opsin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0016028"(rhabdomere)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0016060"(metarhodopsin inactivation)|go:"GO:0045494"(photoreceptor cell maintenance)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|reactome:R-DME-432720|reactome:R-DME-432722|reactome:R-DME-456926|reactome:R-DME-5099900|reactome:R-DME-5674135|reactome:R-DME-8856825|reactome:R-DME-8856828 pubmed:7973725(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:HJLSoXvFeTRzj6pgJKay21a6l3U7227 rogid:+++ZYm3qJWJuYsjsSHn2G7AWOoM7227 intact-crc:986AA181B95D92E2|rigid:jllLB5i7zDzaV3ECKSZ6bzIi/SI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q00168 uniprotkb:P19107 intact:EBI-124595|uniprotkb:Q59DP1|uniprotkb:Q59DP2|uniprotkb:Q9V495|ensemblmetazoa:FBpp0099496|ensemblmetazoa:FBpp0289607 intact:EBI-145046|uniprotkb:Q9VSN6|ensemblmetazoa:FBpp0076326 psi-mi:kcc2a_drome(display_long)|uniprotkb:CaMKII(gene name)|psi-mi:CaMKII(display_short)|uniprotkb:CaM(gene name synonym)|uniprotkb:CG18069(orf name) psi-mi:arrb_drome(display_long)|uniprotkb:Arr2(gene name)|psi-mi:Arr2(display_short)|uniprotkb:ArrB(gene name synonym)|uniprotkb:Phosrestin I(gene name synonym)|uniprotkb:Arrestin-B(gene name synonym)|uniprotkb:Arrestin-2(gene name synonym)|uniprotkb:49 kDa arrestin-like protein(gene name synonym)|uniprotkb:CG5962(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871438 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0264607|refseq:NP_001162832.1|refseq:NP_001014696.1|refseq:NP_524635.3|refseq:NP_001162831.1|refseq:NP_726633.2|refseq:NP_726634.1|refseq:NP_726635.2|refseq:NP_726636.2|ensemblmetazoa:FBgn0264607(gene)|ensemblmetazoa:FBtr0100146(transcript)|ensemblmetazoa:FBtr0300378(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007611"(learning or memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007619"(courtship behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060278"(regulation of ovulation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:5FG8|rcsb pdb:5H9B|rcsb pdb:5HU3|reactome:R-DME-3371571|reactome:R-DME-4086398|reactome:R-DME-438066|reactome:R-DME-5578775|reactome:R-DME-5673000|reactome:R-DME-936837 refseq:NP_523976.1|flybase:FBgn0000121|ensemblmetazoa:FBgn0000121(gene)|ensemblmetazoa:FBtr0076599(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002046"(opsin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0016029"(subrhabdomeral cisterna)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0016060"(metarhodopsin inactivation)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0045494"(photoreceptor cell maintenance)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P19107|reactome:R-DME-432720|reactome:R-DME-432722|reactome:R-DME-456926|reactome:R-DME-5099900|reactome:R-DME-5674135|reactome:R-DME-8856825|reactome:R-DME-8856828|go:"GO:0016028"(rhabdomere)|dip:DIP-20598N pubmed:8185954(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:jUkYZ4jMtpk9BQOvqv7fXANyxNo7227 rogid:coMMEg0FkdIuzUqT0bKZPVCH3tA7227 intact-crc:296AF5DA13B76E63|rigid:e/IhlIuxndZryDBKd+u5P4nLuys false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20659 uniprotkb:Q9VW15 intact:EBI-591327|ensemblmetazoa:FBpp0082406|ensemblmetazoa:FBpp0082409|uniprotkb:Q27255|uniprotkb:Q27327|uniprotkb:Q8INF9|uniprotkb:Q960R2|uniprotkb:Q9VFL1|uniprotkb:A4V2V9|uniprotkb:A4V2W0|intact:EBI-3404288|intact:EBI-3417031|intact:EBI-9922180|intact:EBI-9933604 intact:EBI-124480|uniprotkb:Q24189|uniprotkb:Q8MQX5|ensemblmetazoa:FBpp0297151|ensemblmetazoa:FBpp0297152|intact:EBI-3414333|uniprotkb:A8WHI9|uniprotkb:M9NFL0 psi-mi:trx_drome(display_long)|uniprotkb:KMT2A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2A(gene name synonym)|uniprotkb:trx(gene name)|psi-mi:trx(display_short)|uniprotkb:CG8651(orf name)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:ash1_drome(display_long)|uniprotkb:ash1(gene name)|psi-mi:ash1(display_short)|uniprotkb:CG8887(orf name)|uniprotkb:KMT2H(gene name synonym)|uniprotkb:Absent small and homeotic disks protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2H(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871450 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0003862(gene)|ensemblmetazoa:FBtr0082947(transcript)|ensemblmetazoa:FBtr0082950(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|reactome:R-DME-8936459|reactome:R-DME-8939236|refseq:NP_001014621.1|refseq:NP_476769.1|refseq:NP_476770.1|refseq:NP_599108.1|refseq:NP_599109.1|flybase:FBgn0003862 flybase:FBgn0005386|refseq:NP_001246834.1|refseq:NP_524160.2|ensemblmetazoa:FBgn0005386(gene)|ensemblmetazoa:FBtr0306009(transcript)|ensemblmetazoa:FBtr0306010(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010452"(histone H3-K36 methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0018991"(oviposition)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034770"(histone H4-K20 methylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048096"|go:"GO:0048477"(oogenesis)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0097676"(histone H3-K36 dimethylation)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR036427|interpro:IPR043151|interpro:IPR043319|interpro:IPR043320|dip:DIP-23637N pubmed:10454589(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:LDT4/pLaHAuL/kuZMReRH9ZDrNk7227 rogid:E2mb98G4IutJE+mtX5O7Y22odt07227 intact-crc:F6701C5B8AB124E0|rigid:8deNbJWxl7ZvntP2Tx81Pcf4P0w false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O01368 uniprotkb:Q9VW15 intact:EBI-868028 intact:EBI-124480|uniprotkb:Q24189|uniprotkb:Q8MQX5|ensemblmetazoa:FBpp0297151|ensemblmetazoa:FBpp0297152|intact:EBI-3414333|uniprotkb:A8WHI9|uniprotkb:M9NFL0 psi-mi:o01368_drome(display_long)|uniprotkb:nej(gene name)|psi-mi:nej(display_short)|uniprotkb:CG15319(orf name) psi-mi:ash1_drome(display_long)|uniprotkb:ash1(gene name)|psi-mi:ash1(display_short)|uniprotkb:CG8887(orf name)|uniprotkb:KMT2H(gene name synonym)|uniprotkb:Absent small and homeotic disks protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2H(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871454 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261617|dip:DIP-41329N|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008347"(glial cell migration)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016573"(histone acetylation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0043971"(histone H3-K18 acetylation)|go:"GO:0043974"(histone H3-K27 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043993"("histone acetyltransferase activity (H3-K18 specific)")|go:"GO:0044017"("histone acetyltransferase activity (H3-K27 specific)")|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0098793"(presynapse)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR038547|interpro:IPR043145|mint:O01368 flybase:FBgn0005386|refseq:NP_001246834.1|refseq:NP_524160.2|ensemblmetazoa:FBgn0005386(gene)|ensemblmetazoa:FBtr0306009(transcript)|ensemblmetazoa:FBtr0306010(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010452"(histone H3-K36 methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016571"(histone methylation)|go:"GO:0018991"(oviposition)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034770"(histone H4-K20 methylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048096"|go:"GO:0048477"(oogenesis)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0097676"(histone H3-K36 dimethylation)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR036427|interpro:IPR043151|interpro:IPR043319|interpro:IPR043320|dip:DIP-23637N pubmed:11094082(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:JrQCBD9JpkCR4jgg0/08mthcy5o7227 rogid:E2mb98G4IutJE+mtX5O7Y22odt07227 intact-crc:0BB12C3324E27901|rigid:S0BbA9iBfHYJxDVosi3LggPMjHg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8IR23 uniprotkb:Q27393 intact:EBI-868068|ensemblmetazoa:FBpp0073945|ensemblmetazoa:FBpp0073946|ensemblmetazoa:FBpp0089147|ensemblmetazoa:FBpp0089148|ensemblmetazoa:FBpp0309361|ensemblmetazoa:FBpp0309362 intact:EBI-868053 psi-mi:q8ir23_drome(display_long)|uniprotkb:D-RasGAP(gene name synonym)|uniprotkb:Dmel\CG9209(gene name synonym)|uniprotkb:FBpp0073946(gene name synonym)|uniprotkb:RAS-GAP(gene name synonym)|uniprotkb:RasGAP(gene name synonym)|uniprotkb:Vap(gene name synonym)|uniprotkb:p120RasGAP(gene name synonym)|uniprotkb:rasGap(gene name synonym)|uniprotkb:vap(gene name)|psi-mi:vap(display_short)|uniprotkb:RasGap(gene name synonym)|uniprotkb:Dmel_CG9209(orf name)|uniprotkb:p120 RasGAP(gene name synonym)|uniprotkb:vap-RA(gene name synonym)|uniprotkb:CG9209(orf name) psi-mi:q27393_drome(display_long)|uniprotkb:aurA(gene name)|psi-mi:aurA(display_short)|uniprotkb:aur(gene name synonym)|uniprotkb:CG3068(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871462 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523361.1|refseq:NP_727925.1|refseq:NP_727926.2|refseq:NP_996482.1|flybase:FBgn0003969|refseq:NP_001285314.1|refseq:NP_001285315.1|ensemblmetazoa:FBgn0003969(gene)|ensemblmetazoa:FBtr0074140(transcript)|ensemblmetazoa:FBtr0074141(transcript)|ensemblmetazoa:FBtr0074142(transcript)|ensemblmetazoa:FBtr0074143(transcript)|ensemblmetazoa:FBtr0340415(transcript)|ensemblmetazoa:FBtr0340416(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005122"(torso binding)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016319"(mushroom body development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0120177"(negative regulation of torso signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023152|interpro:IPR028554|interpro:IPR035652|interpro:IPR035841|interpro:IPR035842|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|interpro:IPR039360|mint:Q8IR23|reactome:R-DME-186763|reactome:R-DME-3928662|reactome:R-DME-5218921|reactome:R-DME-8849471 flybase:FBgn0000147|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007279"(pole cell formation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0051233"(spindle midzone)|go:"GO:0051299"(centrosome separation)|go:"GO:0098725"(symmetric cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR030616 pubmed:11976319(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Qc4rc5oeH6PrmaZ75RzhCWjUYgU7227 rogid:4WAWfI01+xRK6R/3WMIVkVNvFnc7227 intact-crc:C17874ABC004E534|rigid:P8HpuWkbQ8KoCHgxtVVjNKPWmmQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q3YNE8 uniprotkb:Q27393 intact:EBI-868084 intact:EBI-868053 psi-mi:q3yne8_drome(display_long)|uniprotkb:tacc(gene name)|psi-mi:tacc(display_short)|uniprotkb:CG9765(orf name) psi-mi:q27393_drome(display_long)|uniprotkb:aurA(gene name)|psi-mi:aurA(display_short)|uniprotkb:aur(gene name synonym)|uniprotkb:CG3068(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871466 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0026620|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007279"(pole cell formation)|go:"GO:0007344"(pronuclear fusion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008104"(protein localization)|go:"GO:0035046"(pronuclear migration) flybase:FBgn0000147|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007279"(pole cell formation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0051233"(spindle midzone)|go:"GO:0051299"(centrosome separation)|go:"GO:0098725"(symmetric cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR030616 pubmed:11827981(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:PO4DpvSnzmXnfZp8sxH2Ohwr4VQ7227 rogid:4WAWfI01+xRK6R/3WMIVkVNvFnc7227 intact-crc:88045863CD899F6E|rigid:3yN9dm4dEKnk84UZJsyqqcLp++Y false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P02299 uniprotkb:Q27393 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 intact:EBI-868053 psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:q27393_drome(display_long)|uniprotkb:aurA(gene name)|psi-mi:aurA(display_short)|uniprotkb:aur(gene name synonym)|uniprotkb:CG3068(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871470 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231 flybase:FBgn0000147|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007279"(pole cell formation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0051233"(spindle midzone)|go:"GO:0051299"(centrosome separation)|go:"GO:0098725"(symmetric cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR030616 pubmed:11352945(see-also)|pubmed:11352945(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 rogid:4WAWfI01+xRK6R/3WMIVkVNvFnc7227 intact-crc:58F9D3F5A78F8E85|rigid:HIGvBAdqOe7hnuAEgBvgQ1nBwiY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q27393 uniprotkb:P54623 intact:EBI-868053 intact:EBI-193803|uniprotkb:Q5BIF5|uniprotkb:Q86NP3|uniprotkb:Q8IHE5|uniprotkb:Q8ML65|uniprotkb:Q9V6P7|uniprotkb:Q9V6P8|uniprotkb:A0A0B4K705|uniprotkb:E1JH56|ensemblmetazoa:FBpp0301623 psi-mi:q27393_drome(display_long)|uniprotkb:aurA(gene name)|psi-mi:aurA(display_short)|uniprotkb:aur(gene name synonym)|uniprotkb:CG3068(orf name) psi-mi:cnn_drome(display_long)|uniprotkb:cnn(gene name)|psi-mi:cnn(display_short)|uniprotkb:CG4832(orf name)|uniprotkb:Protein arrow(gene name synonym)|uniprotkb:Arr(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871474 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0000147|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007279"(pole cell formation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0051233"(spindle midzone)|go:"GO:0051299"(centrosome separation)|go:"GO:0098725"(symmetric cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR030616 refseq:NP_001163141.1|refseq:NP_477084.1|refseq:NP_725297.1|refseq:NP_725298.1|flybase:FBgn0013765|refseq:NP_001246296.1|refseq:NP_001246294.1|refseq:NP_001246295.1|dip:DIP-60708N|ensemblmetazoa:FBgn0013765(gene)|ensemblmetazoa:FBtr0309889(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007279"(pole cell formation)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007494"(midgut development)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031514"(motile cilium)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055059"(asymmetric neuroblast division)|interpro:IPR012943(Spindle associated)|rcsb pdb:5I7C|rcsb pdb:5MVW|rcsb pdb:5MW0|rcsb pdb:5MW9|rcsb pdb:5MWE pubmed:12939255(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:4WAWfI01+xRK6R/3WMIVkVNvFnc7227 rogid:EXt1S96GPY491TofgL0UucbhEyc7227 intact-crc:56AC4A0C5667165C|rigid:KpSIY5s0S/k1xLfgaWNCi+VKDRE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P36872 uniprotkb:Q9V407 intact:EBI-215595|uniprotkb:A4V2M9|uniprotkb:A4V2N0|uniprotkb:Q9VH21|uniprotkb:Q9VH22|intact:EBI-3425822|ensemblmetazoa:FBpp0081664|ensemblmetazoa:FBpp0081665|ensemblmetazoa:FBpp0311386 intact:EBI-196300|uniprotkb:Q9XYC1|ensemblmetazoa:FBpp0084919|ensemblmetazoa:FBpp0084921 psi-mi:2aba_drome(display_long)|uniprotkb:tws(gene name)|psi-mi:tws(display_short)|uniprotkb:Pp2A-85F(gene name synonym)|uniprotkb:aar(gene name synonym)|uniprotkb:CG6235(orf name)|uniprotkb:Protein phosphatase PP2A regulatory subunit B(gene name synonym)|uniprotkb:Protein twins(gene name synonym) psi-mi:axn_drome(display_long)|uniprotkb:Axn(gene name)|psi-mi:Axn(display_short)|uniprotkb:CG7926(orf name)|uniprotkb:Axis inhibition protein(gene name synonym)|uniprotkb:d-Axin(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871478 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287269.1|refseq:NP_476880.1|refseq:NP_476881.1|refseq:NP_599111.1|refseq:NP_599112.1|refseq:NP_599113.1|refseq:NP_731451.1|refseq:NP_731452.1|refseq:NP_731453.1|flybase:FBgn0004889|dip:DIP-19897N|ensemblmetazoa:FBgn0004889(gene)|ensemblmetazoa:FBtr0082186(transcript)|ensemblmetazoa:FBtr0082187(transcript)|ensemblmetazoa:FBtr0345177(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007423"(sensory organ development)|go:"GO:0007447"(imaginal disc pattern formation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0045201"(maintenance of neuroblast polarity)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0050821"(protein stabilization)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|reactome:R-DME-209155|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-2995383|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-69231|reactome:R-DME-69273|reactome:R-DME-975957 refseq:NP_733336.1|refseq:NP_733337.1|flybase:FBgn0026597|dip:DIP-20929N|ensemblmetazoa:FBgn0026597(gene)|ensemblmetazoa:FBtr0085553(transcript)|ensemblmetazoa:FBtr0085555(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0042594"(response to starvation)|go:"GO:0048477"(oogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-209155|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-432553|reactome:R-DME-4641257|reactome:R-DME-4641262|reactome:R-DME-5689880 pubmed:10838083(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:V2pttZ+LGNMPo/0W9zBX+DG9Bxk7227 rogid:DLh/oPS70AHp3EC8ZZOspfCGrLA7227 intact-crc:37AC38DE69CFD610|rigid:d1W4KEnOWZR0AHBD/1b4kcQqTNw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18431 uniprotkb:Q9V407 intact:EBI-242141|uniprotkb:O76881|uniprotkb:P23646|uniprotkb:Q27603|uniprotkb:Q27604|uniprotkb:Q27605|uniprotkb:Q8MRF7|uniprotkb:Q9NF42|uniprotkb:Q9U094|uniprotkb:Q9W4X3|ensemblmetazoa:FBpp0070449|ensemblmetazoa:FBpp0070451|ensemblmetazoa:FBpp0070452|ensemblmetazoa:FBpp0070453|ensemblmetazoa:FBpp0089158|ensemblmetazoa:FBpp0089162 intact:EBI-196300|uniprotkb:Q9XYC1|ensemblmetazoa:FBpp0084919|ensemblmetazoa:FBpp0084921 psi-mi:sgg_drome(display_long)|uniprotkb:sgg(gene name)|psi-mi:sgg(display_short)|uniprotkb:zw3(gene name synonym)|uniprotkb:CG2621(orf name)|uniprotkb:Protein zeste-white 3(gene name synonym)|uniprotkb:gsk3(gene name synonym) psi-mi:axn_drome(display_long)|uniprotkb:Axn(gene name)|psi-mi:Axn(display_short)|uniprotkb:CG7926(orf name)|uniprotkb:Axis inhibition protein(gene name synonym)|uniprotkb:d-Axin(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871482 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476714.1|refseq:NP_476715.1|refseq:NP_476716.2|refseq:NP_599105.1|refseq:NP_726822.1|refseq:NP_726823.1|refseq:NP_996335.1|refseq:NP_996336.1|refseq:NP_996337.1|refseq:NP_996338.1|flybase:FBgn0003371|dip:DIP-39170N|ensemblmetazoa:FBgn0003371(gene)|ensemblmetazoa:FBtr0070466(transcript)|ensemblmetazoa:FBtr0070468(transcript)|ensemblmetazoa:FBtr0070469(transcript)|ensemblmetazoa:FBtr0070470(transcript)|ensemblmetazoa:FBtr0070472(transcript)|ensemblmetazoa:FBtr0070473(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007165"(signal transduction)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007507"(heart development)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008355"(olfactory learning)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0022416"(chaeta development)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030424"(axon)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035324"(female germline ring canal)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045169"(fusome)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046959"(habituation)|go:"GO:0048477"(oogenesis)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070884"(regulation of calcineurin-NFAT signaling cascade)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209387|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3371453|reactome:R-DME-399956|reactome:R-DME-432553|reactome:R-DME-4641262|reactome:R-DME-5610785 refseq:NP_733336.1|refseq:NP_733337.1|flybase:FBgn0026597|dip:DIP-20929N|ensemblmetazoa:FBgn0026597(gene)|ensemblmetazoa:FBtr0085553(transcript)|ensemblmetazoa:FBtr0085555(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0042594"(response to starvation)|go:"GO:0048477"(oogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-209155|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-432553|reactome:R-DME-4641257|reactome:R-DME-4641262|reactome:R-DME-5689880 pubmed:10838083(see-also)|pubmed:12711303(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:sUjAtUAobW55mTZBsRiQg0K1U9o7227 rogid:DLh/oPS70AHp3EC8ZZOspfCGrLA7227 intact-crc:E3C05064D97D8F54|rigid:lS28UXqiXHI3f/e0wLY22bP6J0c false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P51140 uniprotkb:Q9V407 intact:EBI-499383|ensemblmetazoa:FBpp0073310|uniprotkb:Q494J5|uniprotkb:Q9VYZ9 intact:EBI-196300|uniprotkb:Q9XYC1|ensemblmetazoa:FBpp0084919|ensemblmetazoa:FBpp0084921 psi-mi:dsh_drome(display_long)|uniprotkb:dsh(gene name)|psi-mi:dsh(display_short)|uniprotkb:CG18361(orf name) psi-mi:axn_drome(display_long)|uniprotkb:Axn(gene name)|psi-mi:Axn(display_short)|uniprotkb:CG7926(orf name)|uniprotkb:Axis inhibition protein(gene name synonym)|uniprotkb:d-Axin(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871486 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511118.2|flybase:FBgn0000499|ensemblmetazoa:FBgn0000499(gene)|ensemblmetazoa:FBtr0073454(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-201688|reactome:R-DME-2028269|reactome:R-DME-209440|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641258|reactome:R-DME-4641262|reactome:R-DME-5099900|reactome:R-DME-5663220|reactome:R-DME-8856825|reactome:R-DME-8856828|interpro:IPR038207 refseq:NP_733336.1|refseq:NP_733337.1|flybase:FBgn0026597|dip:DIP-20929N|ensemblmetazoa:FBgn0026597(gene)|ensemblmetazoa:FBtr0085553(transcript)|ensemblmetazoa:FBtr0085555(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0042594"(response to starvation)|go:"GO:0048477"(oogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-209155|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-432553|reactome:R-DME-4641257|reactome:R-DME-4641262|reactome:R-DME-5689880 pubmed:10838083(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:zXo1t6bIifQ3/t3hf/MVeEuPw9A7227 rogid:DLh/oPS70AHp3EC8ZZOspfCGrLA7227 intact-crc:7B821A913A2E937B|rigid:ZJA4kPluoihikc9+YAHd5HSwfls false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P54367 uniprotkb:Q9V407 intact:EBI-129996|uniprotkb:A4V4D3|uniprotkb:Q0KHT2|uniprotkb:Q9VYK2|ensemblmetazoa:FBpp0073513|ensemblmetazoa:FBpp0073515|ensemblmetazoa:FBpp0289609|ensemblmetazoa:FBpp0309354|ensemblmetazoa:FBpp0311372|ensemblmetazoa:FBpp0311373 intact:EBI-196300|uniprotkb:Q9XYC1|ensemblmetazoa:FBpp0084919|ensemblmetazoa:FBpp0084921 psi-mi:kc1a_drome(display_long)|uniprotkb:CkIalpha(gene name)|psi-mi:CkIalpha(display_short)|uniprotkb:CKI(gene name synonym)|uniprotkb:CG2028(orf name) psi-mi:axn_drome(display_long)|uniprotkb:Axn(gene name)|psi-mi:Axn(display_short)|uniprotkb:CG7926(orf name)|uniprotkb:Axis inhibition protein(gene name synonym)|uniprotkb:d-Axin(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871490 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162737.1|refseq:NP_511140.1|refseq:NP_727631.1|refseq:NP_727632.1|flybase:FBgn0015024|ensemblmetazoa:FBtr0073680(transcript)|ensemblmetazoa:FBtr0073682(transcript)|ensemblmetazoa:FBtr0300380(transcript)|ensemblmetazoa:FBtr0340408(transcript)|ensemblmetazoa:FBtr0345162(transcript)|ensemblmetazoa:FBtr0345163(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-432553|reactome:R-DME-5610785|reactome:R-DME-5635838|refseq:NP_001285163.1|refseq:NP_001285164.1|ensemblmetazoa:FBgn0015024(gene)|dip:DIP-22041N refseq:NP_733336.1|refseq:NP_733337.1|flybase:FBgn0026597|dip:DIP-20929N|ensemblmetazoa:FBgn0026597(gene)|ensemblmetazoa:FBtr0085553(transcript)|ensemblmetazoa:FBtr0085555(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0042594"(response to starvation)|go:"GO:0048477"(oogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-209155|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-432553|reactome:R-DME-4641257|reactome:R-DME-4641262|reactome:R-DME-5689880 pubmed:11955436(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Ze6yIkD2EQvC/BIhGbjP6MoS8aI7227 rogid:DLh/oPS70AHp3EC8ZZOspfCGrLA7227 intact-crc:B59C24A99DC13615|rigid:Y5owxa6OZyfhInnP1oXHuJYrPgs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:A1Z870 uniprotkb:Q9V407 intact:EBI-868089|ensemblmetazoa:FBpp0087436 intact:EBI-196300|uniprotkb:Q9XYC1|ensemblmetazoa:FBpp0084919|ensemblmetazoa:FBpp0084921 psi-mi:a1z870_drome(display_long)|uniprotkb:CAP(gene name)|psi-mi:CAP(display_short)|uniprotkb:CG18409(gene name synonym)|uniprotkb:CG3451(gene name synonym)|uniprotkb:DCAP(gene name synonym)|uniprotkb:Dmel\CG18408(gene name synonym)|uniprotkb:Rexin(gene name synonym)|uniprotkb:Vinexin(gene name synonym)|uniprotkb:cap(gene name synonym)|uniprotkb:rexin(gene name synonym)|uniprotkb:CG18408(orf name)|uniprotkb:Dmel_CG18408(orf name) psi-mi:axn_drome(display_long)|uniprotkb:Axn(gene name)|psi-mi:Axn(display_short)|uniprotkb:CG7926(orf name)|uniprotkb:Axis inhibition protein(gene name synonym)|uniprotkb:d-Axin(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871494 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_995795.1|flybase:FBgn0033504|ensemblmetazoa:FBgn0033504(gene)|ensemblmetazoa:FBtr0088347(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016020"(membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0050954"(sensory perception of mechanical stimulus)|interpro:IPR001452(Src homology-3)|interpro:IPR028506|interpro:IPR036028 refseq:NP_733336.1|refseq:NP_733337.1|flybase:FBgn0026597|dip:DIP-20929N|ensemblmetazoa:FBgn0026597(gene)|ensemblmetazoa:FBtr0085553(transcript)|ensemblmetazoa:FBtr0085555(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0042594"(response to starvation)|go:"GO:0048477"(oogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-209155|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-432553|reactome:R-DME-4641257|reactome:R-DME-4641262|reactome:R-DME-5689880 pubmed:12385759(see-also)|pubmed:12711303(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:uhLMByXuPF8KDQIEqdP3ICNyvrY7227 rogid:DLh/oPS70AHp3EC8ZZOspfCGrLA7227 intact-crc:76F62DF9B1D502E2|rigid:LKPPnl6YPM+3dXPZX5A9cT/MafE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9V407 uniprotkb:Q9V407 intact:EBI-196300|uniprotkb:Q9XYC1|ensemblmetazoa:FBpp0084919|ensemblmetazoa:FBpp0084921 intact:EBI-196300|uniprotkb:Q9XYC1|ensemblmetazoa:FBpp0084919|ensemblmetazoa:FBpp0084921 psi-mi:axn_drome(display_long)|uniprotkb:Axn(gene name)|psi-mi:Axn(display_short)|uniprotkb:CG7926(orf name)|uniprotkb:Axis inhibition protein(gene name synonym)|uniprotkb:d-Axin(gene name synonym) psi-mi:axn_drome(display_long)|uniprotkb:Axn(gene name)|psi-mi:Axn(display_short)|uniprotkb:CG7926(orf name)|uniprotkb:Axis inhibition protein(gene name synonym)|uniprotkb:d-Axin(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871498 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_733336.1|refseq:NP_733337.1|flybase:FBgn0026597|dip:DIP-20929N|ensemblmetazoa:FBgn0026597(gene)|ensemblmetazoa:FBtr0085553(transcript)|ensemblmetazoa:FBtr0085555(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0042594"(response to starvation)|go:"GO:0048477"(oogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-209155|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-432553|reactome:R-DME-4641257|reactome:R-DME-4641262|reactome:R-DME-5689880 refseq:NP_733336.1|refseq:NP_733337.1|flybase:FBgn0026597|dip:DIP-20929N|ensemblmetazoa:FBgn0026597(gene)|ensemblmetazoa:FBtr0085553(transcript)|ensemblmetazoa:FBtr0085555(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0042594"(response to starvation)|go:"GO:0048477"(oogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR001158(DIX)|interpro:IPR014936(Axin beta-catenin binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036305|interpro:IPR038207|interpro:IPR043581|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-209155|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-432553|reactome:R-DME-4641257|reactome:R-DME-4641262|reactome:R-DME-5689880 pubmed:10838083(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:DLh/oPS70AHp3EC8ZZOspfCGrLA7227 rogid:DLh/oPS70AHp3EC8ZZOspfCGrLA7227 intact-crc:4B759B1C48D5D391|rigid:4jwc6Le+gTZNZZsI1j09VXPcP0k false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VQG0 uniprotkb:P26686 intact:EBI-93950|uniprotkb:Q8SWS6|ensemblmetazoa:FBpp0077399|ensemblmetazoa:FBpp0307125 intact:EBI-133905|uniprotkb:Q24252|uniprotkb:Q26277|uniprotkb:Q8IH12|uniprotkb:Q8ING7|uniprotkb:Q8ING8|uniprotkb:Q8ING9|uniprotkb:Q8MZ66|uniprotkb:Q8T0I0|uniprotkb:Q9VFT0|uniprotkb:Q9VFT1|uniprotkb:A4V2U2|uniprotkb:E1JIK1|uniprotkb:E1JIK2|uniprotkb:E1JIK3|uniprotkb:E4NKI6 psi-mi:q9vqg0_drome(display_long)|uniprotkb:CG2848(orf name)|uniprotkb:Dmel_CG2848(orf name)|uniprotkb:Tnpo-SR(gene name)|psi-mi:Tnpo-SR(display_short)|uniprotkb:Dmel\CG2848(gene name synonym)|uniprotkb:TNPO3(gene name synonym)|uniprotkb:Trn-SR(gene name synonym)|uniprotkb:"anon-EST:Posey294"(gene name synonym)|uniprotkb:dTRN-SR(gene name synonym) psi-mi:srr55_drome(display_long)|uniprotkb:B52(gene name)|psi-mi:B52(display_short)|uniprotkb:CG10851(orf name)|uniprotkb:Protein enhancer of deformed(gene name synonym)|uniprotkb:52 kDa bracketing protein(gene name synonym)|uniprotkb:B52 protein(gene name synonym)|uniprotkb:"E(Dfd)"(gene name synonym)|uniprotkb:RS55(gene name synonym)|uniprotkb:SR55(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871502 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_608708.2|flybase:FBgn0031456|ensemblmetazoa:FBgn0031456(gene)|ensemblmetazoa:FBtr0077715(transcript)|ensemblmetazoa:FBtr0335126(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001259961.1 refseq:NP_001163603.1|refseq:NP_001163604.1|refseq:NP_788665.1|refseq:NP_788666.1|refseq:NP_788668.1|refseq:NP_788669.1|refseq:NP_788670.1|flybase:FBgn0004587|refseq:NP_001014619.2|refseq:NP_788667.2|refseq:NP_788671.2|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0044819"(mitotic G1/S transition checkpoint signaling)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051607"(defense response to virus)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|reactome:R-DME-159236|reactome:R-DME-72163|reactome:R-DME-72165|reactome:R-DME-72187|reactome:R-DME-73856|go:"GO:0001178"(regulation of transcriptional start site selection at RNA polymerase II promoter) pubmed:12134081(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:2UfxMPbxdHXFDKaF8f+uejPH6Gk7227 rogid:W93o6QSYDl81WHhwaxV+WaOxo+c7227 intact-crc:966B471C5AF1779A|rigid:1pT6nmIeahNQAtNwvxlpVbVhuDs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8MSB9 uniprotkb:Q9W0K7 intact:EBI-868163 intact:EBI-205029|uniprotkb:Q23968|uniprotkb:Q8MR78|uniprotkb:Q9U1H7|intact:EBI-205042|ensemblmetazoa:FBpp0072538 psi-mi:q8msb9_drome(display_long)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)|uniprotkb:bip2(gene name synonym)|uniprotkb:CG2009(orf name) psi-mi:bab1_drome(display_long)|uniprotkb:bab1(gene name)|psi-mi:bab1(display_short)|uniprotkb:bab(gene name synonym)|uniprotkb:CG9097(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871506 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0026262|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031208"(POZ domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold) flybase:FBgn0004870|refseq:NP_728565.1|dip:DIP-18590N|ensemblmetazoa:FBgn0004870(gene)|ensemblmetazoa:FBtr0072642(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0046660"(female sex differentiation)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048071"(sex-specific pigmentation)|go:"GO:0048086"(negative regulation of developmental pigmentation)|go:"GO:0048092"(negative regulation of male pigmentation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011333(BTB/POZ fold) pubmed:11543621(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Jha1ESa18znwy2HTO9u+8ihLb3w7227 rogid:odDQgISzkCQZxrbMtH2a8z1+kz07227 intact-crc:85B36F6F2845E20B|rigid:O7zY7qQ3gBBkwFEijxAznKQZmF4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9W0K7 uniprotkb:Q9W0K7 intact:EBI-205029|uniprotkb:Q23968|uniprotkb:Q8MR78|uniprotkb:Q9U1H7|intact:EBI-205042|ensemblmetazoa:FBpp0072538 intact:EBI-205029|uniprotkb:Q23968|uniprotkb:Q8MR78|uniprotkb:Q9U1H7|intact:EBI-205042|ensemblmetazoa:FBpp0072538 psi-mi:bab1_drome(display_long)|uniprotkb:bab1(gene name)|psi-mi:bab1(display_short)|uniprotkb:bab(gene name synonym)|uniprotkb:CG9097(orf name) psi-mi:bab1_drome(display_long)|uniprotkb:bab1(gene name)|psi-mi:bab1(display_short)|uniprotkb:bab(gene name synonym)|uniprotkb:CG9097(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871510 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0004870|refseq:NP_728565.1|dip:DIP-18590N|ensemblmetazoa:FBgn0004870(gene)|ensemblmetazoa:FBtr0072642(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0046660"(female sex differentiation)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048071"(sex-specific pigmentation)|go:"GO:0048086"(negative regulation of developmental pigmentation)|go:"GO:0048092"(negative regulation of male pigmentation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011333(BTB/POZ fold) flybase:FBgn0004870|refseq:NP_728565.1|dip:DIP-18590N|ensemblmetazoa:FBgn0004870(gene)|ensemblmetazoa:FBtr0072642(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0046660"(female sex differentiation)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048071"(sex-specific pigmentation)|go:"GO:0048086"(negative regulation of developmental pigmentation)|go:"GO:0048092"(negative regulation of male pigmentation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011333(BTB/POZ fold) pubmed:7760839(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:odDQgISzkCQZxrbMtH2a8z1+kz07227 rogid:odDQgISzkCQZxrbMtH2a8z1+kz07227 intact-crc:B99A2C7F941E7786|rigid:FDuVBUsOBinFfy16sl0yCrWSnnM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8MSB9 uniprotkb:Q9W0K4 intact:EBI-868163 intact:EBI-186941|uniprotkb:Q24001|uniprotkb:Q7YU69|uniprotkb:Q9U1H3|ensemblmetazoa:FBpp0072535 psi-mi:q8msb9_drome(display_long)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)|uniprotkb:bip2(gene name synonym)|uniprotkb:CG2009(orf name) psi-mi:bab2_drome(display_long)|uniprotkb:bab2(gene name)|psi-mi:bab2(display_short)|uniprotkb:BtbII(gene name synonym)|uniprotkb:CG9102(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871514 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0026262|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031208"(POZ domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold) refseq:NP_523879.2|flybase:FBgn0025525|dip:DIP-20101N|ensemblmetazoa:FBgn0025525(gene)|ensemblmetazoa:FBtr0072639(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0061040"(female gonad morphogenesis)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011333(BTB/POZ fold) pubmed:11543621(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Jha1ESa18znwy2HTO9u+8ihLb3w7227 rogid:Dr4kbNdhiY2mCoFzMEVfTgbMgLg7227 intact-crc:B9806F6F05D7A2B6|rigid:vghUl5zTXbwNHsqbiRiqcqCcngg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O96660 uniprotkb:Q23975 intact:EBI-145058|ensemblmetazoa:FBpp0071140|ensemblmetazoa:FBpp0309145 intact:EBI-868170 psi-mi:o96660_drome(display_long)|uniprotkb:Smox(gene name)|psi-mi:Smox(display_short)|uniprotkb:smad2(gene name synonym)|uniprotkb:CG2262(orf name)|uniprotkb:SMAD family member(gene name synonym)|uniprotkb:DSMAD2(gene name synonym)|uniprotkb:DSmad2(gene name synonym)|uniprotkb:Dmel\CG2262(gene name synonym)|uniprotkb:SMAD2(gene name synonym)|uniprotkb:SMOX(gene name synonym)|uniprotkb:Sad(gene name synonym)|uniprotkb:Smad(gene name synonym)|uniprotkb:Smad2(gene name synonym)|uniprotkb:SmoX(gene name synonym)|uniprotkb:dSMAD2(gene name synonym)|uniprotkb:dSmad2(gene name synonym)|uniprotkb:dsmad2(gene name synonym)|uniprotkb:"l(1)G0348"(gene name synonym)|uniprotkb:sad(gene name synonym)|uniprotkb:smox(gene name synonym)|uniprotkb:ted(gene name synonym)|uniprotkb:tmp(gene name synonym)|uniprotkb:Dmel_CG2262(orf name) psi-mi:q23975_drome(display_long)|uniprotkb:babo(gene name)|psi-mi:babo(display_short)|uniprotkb:CG8224(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871518 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511079.1|flybase:FBgn0025800|refseq:NP_001285006.1|ensemblmetazoa:FBgn0025800(gene)|ensemblmetazoa:FBtr0071192(transcript)|ensemblmetazoa:FBtr0340159(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010507"(negative regulation of autophagy)|dip:DIP-18259N|go:"GO:0016319"(mushroom body development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0044719"(regulation of imaginal disc-derived wing size)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048666"(neuron development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090256"(regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|reactome:R-DME-1181150|reactome:R-DME-1502540|reactome:R-DME-2173788|reactome:R-DME-2173789|reactome:R-DME-2173795|reactome:R-DME-2173796|reactome:R-DME-8941855|reactome:R-DME-9617828 flybase:FBgn0011300|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009411"(response to UV)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016319"(mushroom body development)|go:"GO:0016361"(activin receptor activity, type I)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0043235"(receptor complex)|go:"GO:0048179"(activin receptor complex)|go:"GO:0048185"(activin binding)|go:"GO:0048666"(neuron development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|interpro:IPR000333(Activin type II receptor)|interpro:IPR000472(TGF-beta receptor/activin receptor, type I/II)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003605(TGF beta receptor, GS motif)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) pubmed:9887103(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Yp3zkP2CIw7h2/zcG0RD6D6JivE7227 rogid:OTDR+fd/SrcnKaxpz0JLme8eZxA7227 intact-crc:FC09C1D893E8CC77|rigid:zNem4i5PcNgeJt7EBtAvNCjZJts false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KN62 uniprotkb:P22745 intact:EBI-224053|uniprotkb:A8DY85|uniprotkb:A8DY86|uniprotkb:O76279|uniprotkb:Q9U463|intact:EBI-868187|ensemblmetazoa:FBpp0087479 intact:EBI-88504|uniprotkb:Q2PNQ8|uniprotkb:Q2PNQ9|uniprotkb:Q2PNR5|uniprotkb:Q2PNR8|uniprotkb:Q2PNR9|uniprotkb:Q2PNS3|uniprotkb:Q2PNS6|uniprotkb:Q2PNS8|uniprotkb:Q2PNT1|uniprotkb:Q8MRX8|uniprotkb:Q9VBV0|ensemblmetazoa:FBpp0084243 psi-mi:tera_drome(display_long)|uniprotkb:TER94(gene name)|psi-mi:TER94(display_short)|uniprotkb:VCP(gene name synonym)|uniprotkb:Valosin-containing protein homolog(gene name synonym)|uniprotkb:CG2331(orf name) psi-mi:bam_drome(display_long)|uniprotkb:bam(gene name)|psi-mi:bam(display_short)|uniprotkb:CG10422(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871522 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097249.1|refseq:NP_001097250.1|refseq:NP_477369.1|flybase:FBgn0286784|dip:DIP-52184N|ensemblmetazoa:FBgn0286784(gene)|ensemblmetazoa:FBtr0088391(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007279"(pole cell formation)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043186"(P granule)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044754"(autolysosome)|go:"GO:0045169"(fusome)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|rcsb pdb:4RV0|reactome:R-DME-110320|reactome:R-DME-3371511|reactome:R-DME-382556|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-5689896|reactome:R-DME-6798695|reactome:R-DME-8876725|reactome:R-DME-9013407 ensemblmetazoa:FBgn0000158(gene)|ensemblmetazoa:FBtr0084869(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007276"(gamete generation)|go:"GO:0007282"(cystoblast division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045169"(fusome)|go:"GO:0045170"(spectrosome)|go:"GO:0045478"(fusome organization)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0048477"(oogenesis)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0098730"(male germline stem cell symmetric division)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:2000738"(positive regulation of stem cell differentiation)|rcsb pdb:5ONA|rcsb pdb:5ONB|go:"GO:0042078"(germ-line stem cell division)|refseq:NP_476800.1|flybase:FBgn0000158|dip:DIP-48889N pubmed:10564274(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:fnh+1rCUacMwGJRyZV82HEjkNCA7227 rogid:+yKbVZi2wU21FCl18d28yxs8xsQ7227 intact-crc:A462A5A51C626EB3|rigid:87hTrA5ojmBUx4fngp3ngtzxhUo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9W1I2 uniprotkb:P22745 intact:EBI-142483|uniprotkb:Q9W1I3|ensemblmetazoa:FBpp0072141 intact:EBI-88504|uniprotkb:Q2PNQ8|uniprotkb:Q2PNQ9|uniprotkb:Q2PNR5|uniprotkb:Q2PNR8|uniprotkb:Q2PNR9|uniprotkb:Q2PNS3|uniprotkb:Q2PNS6|uniprotkb:Q2PNS8|uniprotkb:Q2PNT1|uniprotkb:Q8MRX8|uniprotkb:Q9VBV0|ensemblmetazoa:FBpp0084243 psi-mi:bgcn_drome(display_long)|uniprotkb:bgcn(gene name)|psi-mi:bgcn(display_short)|uniprotkb:"b(2)gcn"(gene name synonym)|uniprotkb:CG30170(orf name) psi-mi:bam_drome(display_long)|uniprotkb:bam(gene name)|psi-mi:bam(display_short)|uniprotkb:CG10422(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871526 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523832.2|flybase:FBgn0004581|dip:DIP-48890N|ensemblmetazoa:FBgn0004581(gene)|ensemblmetazoa:FBtr0072232(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007281"(germ cell development)|go:"GO:0007282"(cystoblast division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0048477"(oogenesis)|go:"GO:0098730"(male germline stem cell symmetric division)|interpro:IPR002110(Ankyrin)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR027417|interpro:IPR036770 ensemblmetazoa:FBgn0000158(gene)|ensemblmetazoa:FBtr0084869(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007276"(gamete generation)|go:"GO:0007282"(cystoblast division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045169"(fusome)|go:"GO:0045170"(spectrosome)|go:"GO:0045478"(fusome organization)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0048477"(oogenesis)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0098730"(male germline stem cell symmetric division)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:2000738"(positive regulation of stem cell differentiation)|rcsb pdb:5ONA|rcsb pdb:5ONB|go:"GO:0042078"(germ-line stem cell division)|refseq:NP_476800.1|flybase:FBgn0000158|dip:DIP-48889N pubmed:10433830(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:9FSjffCDwFNl3/5tWrHGdqohIr07227 rogid:+yKbVZi2wU21FCl18d28yxs8xsQ7227 intact-crc:5648232E7F7B285B|rigid:ZpZs0Od4hSbPe6jo+S1HtvcHM3c false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P15348 uniprotkb:P91663 intact:EBI-134105|uniprotkb:Q9VIW2|uniprotkb:Q6NR40|uniprotkb:M9PDQ1|ensemblmetazoa:FBpp0080825|ensemblmetazoa:FBpp0304598 intact:EBI-868204 psi-mi:top2_drome(display_long)|uniprotkb:Top2(gene name)|psi-mi:Top2(display_short)|uniprotkb:CG10223(orf name)|uniprotkb:DNA topoisomerase II(gene name synonym) psi-mi:p91663_drome(display_long)|uniprotkb:barr(gene name)|psi-mi:barr(display_short)|uniprotkb:CG10726(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871530 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0284220|refseq:NP_476760.1|refseq:NP_001260580.1|ensemblmetazoa:FBgn0284220(gene)|ensemblmetazoa:FBtr0081287(transcript)|ensemblmetazoa:FBtr0332320(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006342"|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008623"(CHRAC)|go:"GO:0030261"(chromosome condensation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|interpro:IPR020568|interpro:IPR031660|interpro:IPR034157|interpro:IPR036890|reactome:R-DME-4615885 flybase:FBgn0014127|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0008258"(head involution)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030261"(chromosome condensation)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048567"(ectodermal digestive tract morphogenesis)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0072587"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity")|interpro:IPR022816 pubmed:8978614(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:EkijDVP5cT0HlKzmQhXsNTYxwms7227 rogid:X6EKD4BUeBjdstW2Cq2/gTw3USk7227 intact-crc:180AE95F4FFC838C|rigid:o9MHneQa7doaMRhsKuO2jrTNA50 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P39769 uniprotkb:P91663 intact:EBI-300360|uniprotkb:O46097|uniprotkb:Q9W521|uniprotkb:Q9W522|ensemblmetazoa:FBpp0070416 intact:EBI-868204 psi-mi:php_drome(display_long)|uniprotkb:CG18412(orf name)|uniprotkb:ph-p(gene name)|psi-mi:ph-p(display_short) psi-mi:p91663_drome(display_long)|uniprotkb:barr(gene name)|psi-mi:barr(display_short)|uniprotkb:CG10726(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871534 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0004861(gene)|ensemblmetazoa:FBtr0070432(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051087"(chaperone binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P39769|rcsb pdb:1KW4|rcsb pdb:1PK1|reactome:R-DME-3108214|reactome:R-DME-3899300|go:"GO:0030713"(ovarian follicle cell stalk formation)|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724|reactome:R-DME-8953750|refseq:NP_476871.2|flybase:FBgn0004861|dip:DIP-19426N flybase:FBgn0014127|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0008258"(head involution)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030261"(chromosome condensation)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048567"(ectodermal digestive tract morphogenesis)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0072587"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity")|interpro:IPR022816 pubmed:11172718(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:3pxds6HiNRg2p/Vcl7hFNcPInFI7227 rogid:X6EKD4BUeBjdstW2Cq2/gTw3USk7227 intact-crc:FB4856558A7280D7|rigid:B006fM2ZYw791a8ZTXQnhqsAkSc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VKN7 uniprotkb:P91663 intact:EBI-118412|uniprotkb:Q9XTQ0|ensemblmetazoa:FBpp0079769 intact:EBI-868204 psi-mi:aurkb_drome(display_long)|uniprotkb:aurB(gene name)|psi-mi:aurB(display_short)|uniprotkb:IPL1/Aurora-like protein kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Ial(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-B(gene name synonym)|uniprotkb:ial(gene name synonym)|uniprotkb:CG6620(orf name) psi-mi:p91663_drome(display_long)|uniprotkb:barr(gene name)|psi-mi:barr(display_short)|uniprotkb:CG10726(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871538 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477336.1|flybase:FBgn0024227|ensemblmetazoa:FBgn0024227(gene)|ensemblmetazoa:FBtr0080180(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006325"(chromatin organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030496"(midbody)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0051233"(spindle midzone)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061952"(midbody abscission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990385"(meiotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028772|interpro:IPR030616|reactome:R-DME-174178|reactome:R-DME-4615885|reactome:R-DME-6804756 flybase:FBgn0014127|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0008258"(head involution)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030261"(chromosome condensation)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048567"(ectodermal digestive tract morphogenesis)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0072587"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity")|interpro:IPR022816 pubmed:11266459(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:RuIbYEJ93iyYiQpITOftFN7pMJI7227 rogid:X6EKD4BUeBjdstW2Cq2/gTw3USk7227 intact-crc:E2C244E7B658E34B|rigid:8AjFTMzjP+UVTssEWmu933+V2I0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O97111 uniprotkb:O96782 intact:EBI-186645|ensemblmetazoa:FBpp0074229|ensemblmetazoa:FBpp0074230 intact:EBI-867941 psi-mi:o97111_drome(display_long)|uniprotkb:par-6(gene name)|psi-mi:par-6(display_short)|uniprotkb:DPar-6(gene name synonym)|uniprotkb:DPar6(gene name synonym)|uniprotkb:Dm-Par-6(gene name synonym)|uniprotkb:Dm-Par6(gene name synonym)|uniprotkb:DmPAR-6(gene name synonym)|uniprotkb:DmPar-6(gene name synonym)|uniprotkb:DmPar6(gene name synonym)|uniprotkb:Dmel\CG5884(gene name synonym)|uniprotkb:Dmpar6(gene name synonym)|uniprotkb:PAR-6(gene name synonym)|uniprotkb:PAR6(gene name synonym)|uniprotkb:Par(gene name synonym)|uniprotkb:Par-6(gene name synonym)|uniprotkb:Par6(gene name synonym)|uniprotkb:dPAR-6(gene name synonym)|uniprotkb:dPar-6(gene name synonym)|uniprotkb:dmPar-6(gene name synonym)|uniprotkb:par(gene name synonym)|uniprotkb:par6(gene name synonym)|uniprotkb:Dmel_CG5884(orf name)|uniprotkb:CG5884(orf name) psi-mi:o96782_drome(display_long)|uniprotkb:baz(gene name)|psi-mi:baz(display_short)|uniprotkb:bazooka(gene name synonym)|uniprotkb:CG5055(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871542 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_573238.1|flybase:FBgn0026192|refseq:NP_728094.1|dip:DIP-17759N|ensemblmetazoa:FBgn0026192(gene)|ensemblmetazoa:FBtr0074455(transcript)|ensemblmetazoa:FBtr0074456(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007416"(synapse assembly)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016332"(establishment or maintenance of polarity of embryonic epithelium)|go:"GO:0035003"(subapical complex)|go:"GO:0043195"(terminal bouton)|go:"GO:0045176"(apical protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045196"(establishment or maintenance of neuroblast polarity)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0097482"(muscle cell postsynaptic specialization)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR034868|interpro:IPR034873|interpro:IPR036034|rcsb pdb:1RY4|rcsb pdb:1RZX|rcsb pdb:1X8S|rcsb pdb:2LC6|rcsb pdb:2LC7|rcsb pdb:5I7Z|reactome:R-DME-2173791|reactome:R-DME-4608870|reactome:R-DME-9013149 flybase:FBgn0000163|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005912"(adherens junction)|go:"GO:0005914"(spot adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007299"(ovarian follicle cell-cell adhesion)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007377"(germ-band extension)|go:"GO:0007416"(synapse assembly)|go:"GO:0008104"(protein localization)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030709"(border follicle cell delamination)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0072002"(Malpighian tubule development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:O96782 pubmed:11146625(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:L8COGHmbjA0Br5eyBQPvEeCEQTw7227 rogid:UT2HtbwNRFuGCQL1dHzbkIBnJe47227 intact-crc:6E20B658C341E284|rigid:5IWohK8D50BbdmuR/QGMGfBsRuE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16554 uniprotkb:O96782 intact:EBI-429581|uniprotkb:Q8IPE9|uniprotkb:Q961A6|uniprotkb:Q9VLB8|uniprotkb:B8A413|uniprotkb:B8A419|ensemblmetazoa:FBpp0079420|ensemblmetazoa:FBpp0308609 intact:EBI-867941 psi-mi:numb_drome(display_long)|uniprotkb:CG3779(orf name)|uniprotkb:numb(gene name)|psi-mi:numb(display_short) psi-mi:o96782_drome(display_long)|uniprotkb:baz(gene name)|psi-mi:baz(display_short)|uniprotkb:bazooka(gene name synonym)|uniprotkb:CG5055(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871546 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523523.2|refseq:NP_723460.1|flybase:FBgn0002973|refseq:NP_001260291.1|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051642"(centrosome localization)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|mint:P16554|go:"GO:0045178"(basal part of cell)|rcsb pdb:1DDM|rcsb pdb:2NMB|rcsb pdb:5YI7|rcsb pdb:5YI8|reactome:R-DME-5610780|reactome:R-DME-5632684|ensemblmetazoa:FBgn0002973(gene)|ensemblmetazoa:FBtr0079822(transcript)|ensemblmetazoa:FBtr0339526(transcript)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005112"(Notch binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008104"(protein localization)|go:"GO:0008347"(glial cell migration)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0045035"(sensory organ precursor cell division) flybase:FBgn0000163|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005912"(adherens junction)|go:"GO:0005914"(spot adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007299"(ovarian follicle cell-cell adhesion)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007377"(germ-band extension)|go:"GO:0007416"(synapse assembly)|go:"GO:0008104"(protein localization)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030709"(border follicle cell delamination)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0072002"(Malpighian tubule development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:O96782 pubmed:11734647(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:9FGhbcAA6k1LCDHPoLSXwEEVwzY7227 rogid:UT2HtbwNRFuGCQL1dHzbkIBnJe47227 intact-crc:2F396588D0AF669E|rigid:WjX2DQIhFBtKqdNmkFI6RMnue9M false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24367 uniprotkb:O96782 intact:EBI-868219 intact:EBI-867941 psi-mi:q24367_drome(display_long)|uniprotkb:insc(gene name)|psi-mi:insc(display_short)|uniprotkb:inscuteable(gene name synonym)|uniprotkb:CG11312(orf name) psi-mi:o96782_drome(display_long)|uniprotkb:baz(gene name)|psi-mi:baz(display_short)|uniprotkb:bazooka(gene name synonym)|uniprotkb:CG5055(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871550 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0011674|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006403"(RNA localization)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008104"(protein localization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045176"(apical protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039921|rcsb pdb:5A7D flybase:FBgn0000163|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005912"(adherens junction)|go:"GO:0005914"(spot adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007299"(ovarian follicle cell-cell adhesion)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007377"(germ-band extension)|go:"GO:0007416"(synapse assembly)|go:"GO:0008104"(protein localization)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030709"(border follicle cell delamination)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0072002"(Malpighian tubule development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:O96782 pubmed:10591217(see-also)|pubmed:10753746(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:gqUxZqIF4l7DUDBAs57rDl6o79U7227 rogid:UT2HtbwNRFuGCQL1dHzbkIBnJe47227 intact-crc:8915789D4667FE71|rigid:m70vcXxAx5rAFWQqaQ7QbyHlPL8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18475 uniprotkb:P09081 intact:EBI-195402|uniprotkb:A8DY54|uniprotkb:A8DY56|uniprotkb:Q9V4R2|ensemblmetazoa:FBpp0088012 intact:EBI-196628|intact:EBI-1628133|uniprotkb:Q5BI92|uniprotkb:Q86BA9|uniprotkb:Q86BP2|uniprotkb:Q8INR7|uniprotkb:Q8ST46|uniprotkb:Q8STB1|uniprotkb:Q8T9S9|uniprotkb:Q8T9T0|uniprotkb:Q8T9T1|uniprotkb:Q95TN3|uniprotkb:Q9UAM0|uniprotkb:Q9VI47|ensemblmetazoa:FBpp0081168 psi-mi:torso_drome(display_long)|uniprotkb:tor(gene name)|psi-mi:tor(display_short)|uniprotkb:CG1389(orf name) psi-mi:bcd_drome(display_long)|uniprotkb:bcd(gene name)|psi-mi:bcd(display_short)|uniprotkb:CG1034(orf name)|uniprotkb:PRD-4(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871554 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097212.2|refseq:NP_476762.1|flybase:FBgn0003733|ensemblmetazoa:FBgn0003733(gene)|ensemblmetazoa:FBtr0088938(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007278"(pole cell fate determination)|go:"GO:0007280"(pole cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0046957"(negative phototaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116 refseq:NP_476825.1|refseq:NP_731111.1|refseq:NP_731113.2|refseq:NP_788587.1|refseq:NP_788588.1|flybase:FBgn0000166|ensemblmetazoa:FBgn0000166(gene)|ensemblmetazoa:FBtr0081668(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007355"(anterior region determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008358"(maternal determination of anterior/posterior axis, embryo)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030371"(translation repressor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1ZQ3 pubmed:10603346(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xto08nbumwFlew52tyO4IgeMEqs7227 rogid:Nt5CxfBC6SP6auZB0DEeSOXQHko7227 intact-crc:5D920F143F9F9D57|rigid:t/7N+cdwrCNPFUXxgux/XXOaNxM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P49847 uniprotkb:P09081 intact:EBI-136204|uniprotkb:Q9VW16|uniprotkb:Q961B6|ensemblmetazoa:FBpp0074709 intact:EBI-196628|intact:EBI-1628133|uniprotkb:Q5BI92|uniprotkb:Q86BA9|uniprotkb:Q86BP2|uniprotkb:Q8INR7|uniprotkb:Q8ST46|uniprotkb:Q8STB1|uniprotkb:Q8T9S9|uniprotkb:Q8T9T0|uniprotkb:Q8T9T1|uniprotkb:Q95TN3|uniprotkb:Q9UAM0|uniprotkb:Q9VI47|ensemblmetazoa:FBpp0081168 psi-mi:taf6_drome(display_long)|uniprotkb:Taf6(gene name)|psi-mi:Taf6(display_short)|uniprotkb:Taf60(gene name synonym)|uniprotkb:CG32211(orf name)|uniprotkb:Transcription initiation factor TFIID 62 kDa subunit(gene name synonym)|uniprotkb:TAFII-60(gene name synonym)|uniprotkb:TAFII-62(gene name synonym) psi-mi:bcd_drome(display_long)|uniprotkb:bcd(gene name)|psi-mi:bcd(display_short)|uniprotkb:CG1034(orf name)|uniprotkb:PRD-4(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871558 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524161.2|flybase:FBgn0010417|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR011442(Protein of unknown function DUF1546)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037796|rcsb pdb:1TAF|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|ensemblmetazoa:FBgn0010417(gene)|ensemblmetazoa:FBtr0074941(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|dip:DIP-778N refseq:NP_476825.1|refseq:NP_731111.1|refseq:NP_731113.2|refseq:NP_788587.1|refseq:NP_788588.1|flybase:FBgn0000166|ensemblmetazoa:FBgn0000166(gene)|ensemblmetazoa:FBtr0081668(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007355"(anterior region determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008358"(maternal determination of anterior/posterior axis, embryo)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030371"(translation repressor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1ZQ3 pubmed:8525367(see-also)|pubmed:10200284(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:B6rVKKVnmMjwbfPHdfjlEg2QdHs7227 rogid:Nt5CxfBC6SP6auZB0DEeSOXQHko7227 intact-crc:8DD74C9C4C043993|rigid:jHM1AyL/2JsqHfi/3dt8noAba1g false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P47825 uniprotkb:P09081 intact:EBI-277958|uniprotkb:P49845|uniprotkb:Q0E8E3|uniprotkb:Q1LZ31|uniprotkb:Q8T9E0|uniprotkb:Q9VUY7|ensemblmetazoa:FBpp0075205|ensemblmetazoa:FBpp0075206|ensemblmetazoa:FBpp0291125|ensemblmetazoa:FBpp0311865 intact:EBI-196628|intact:EBI-1628133|uniprotkb:Q5BI92|uniprotkb:Q86BA9|uniprotkb:Q86BP2|uniprotkb:Q8INR7|uniprotkb:Q8ST46|uniprotkb:Q8STB1|uniprotkb:Q8T9S9|uniprotkb:Q8T9T0|uniprotkb:Q8T9T1|uniprotkb:Q95TN3|uniprotkb:Q9UAM0|uniprotkb:Q9VI47|ensemblmetazoa:FBpp0081168 psi-mi:taf4_drome(display_long)|uniprotkb:Transcription initiation factor TFIID 110 kDa subunit(gene name synonym)|uniprotkb:110 kDa TBP-associated factor(gene name synonym)|uniprotkb:Taf4(gene name)|psi-mi:Taf4(display_short)|uniprotkb:TAF110(gene name synonym)|uniprotkb:CG5444(orf name) psi-mi:bcd_drome(display_long)|uniprotkb:bcd(gene name)|psi-mi:bcd(display_short)|uniprotkb:CG1034(orf name)|uniprotkb:PRD-4(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871562 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_788511.1|refseq:NP_996101.1|flybase:FBgn0010280|refseq:NP_001287077.1|refseq:NP_001163453.1|refseq:NP_524102.1|refseq:NP_730109.1|dip:DIP-237N|ensemblmetazoa:FBgn0010280(gene)|ensemblmetazoa:FBtr0075448(transcript)|ensemblmetazoa:FBtr0075449(transcript)|ensemblmetazoa:FBtr0301911(transcript)|ensemblmetazoa:FBtr0345951(transcript)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR007900(Transcription initiation factor TFIID component TAF4)|interpro:IPR009072(Histone-fold)|interpro:IPR037249|mint:P47825|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 refseq:NP_476825.1|refseq:NP_731111.1|refseq:NP_731113.2|refseq:NP_788587.1|refseq:NP_788588.1|flybase:FBgn0000166|ensemblmetazoa:FBgn0000166(gene)|ensemblmetazoa:FBtr0081668(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007355"(anterior region determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008358"(maternal determination of anterior/posterior axis, embryo)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030371"(translation repressor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1ZQ3 pubmed:8525367(see-also)|pubmed:10200284(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KMwgcLywcp/YxxTLBjtmqXNPhdo7227 rogid:Nt5CxfBC6SP6auZB0DEeSOXQHko7227 intact-crc:0A567F2494BC9D44|rigid:x2X0fq7VoT+CSPa2fGkzcgwppB0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O18353 uniprotkb:P09081 intact:EBI-130074|ensemblmetazoa:FBpp0072100 intact:EBI-196628|intact:EBI-1628133|uniprotkb:Q5BI92|uniprotkb:Q86BA9|uniprotkb:Q86BP2|uniprotkb:Q8INR7|uniprotkb:Q8ST46|uniprotkb:Q8STB1|uniprotkb:Q8T9S9|uniprotkb:Q8T9T0|uniprotkb:Q8T9T1|uniprotkb:Q95TN3|uniprotkb:Q9UAM0|uniprotkb:Q9VI47|ensemblmetazoa:FBpp0081168 psi-mi:o18353_drome(display_long)|uniprotkb:Chi(gene name)|psi-mi:Chi(display_short)|uniprotkb:Chip(gene name synonym)|uniprotkb:CHIP(gene name synonym)|uniprotkb:Dmel\CG3924(gene name synonym)|uniprotkb:LDB(gene name synonym)|uniprotkb:Ldb(gene name synonym)|uniprotkb:chi(gene name synonym)|uniprotkb:chip(gene name synonym)|uniprotkb:dLDB(gene name synonym)|uniprotkb:dLdb(gene name synonym)|uniprotkb:"l(2)04405"(gene name synonym)|uniprotkb:"l(2)k04405"(gene name synonym)|uniprotkb:CG3924(orf name)|uniprotkb:Dmel_CG3924(orf name) psi-mi:bcd_drome(display_long)|uniprotkb:bcd(gene name)|psi-mi:bcd(display_short)|uniprotkb:CG1034(orf name)|uniprotkb:PRD-4(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871566 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477082.1|flybase:FBgn0013764|ensemblmetazoa:FBgn0013764(gene)|ensemblmetazoa:FBtr0072191(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007563"(regulation of eclosion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030274"(LIM domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070983"(dendrite guidance)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|go:"GO:0010468"(regulation of gene expression) refseq:NP_476825.1|refseq:NP_731111.1|refseq:NP_731113.2|refseq:NP_788587.1|refseq:NP_788588.1|flybase:FBgn0000166|ensemblmetazoa:FBgn0000166(gene)|ensemblmetazoa:FBtr0081668(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007355"(anterior region determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008358"(maternal determination of anterior/posterior axis, embryo)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030371"(translation repressor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1ZQ3 pubmed:10688916(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:czIwVtaJWBnWCANwkEZHnvpMrn87227 rogid:Nt5CxfBC6SP6auZB0DEeSOXQHko7227 intact-crc:CC9A384F05D6B99F|rigid:RiTzpwvaQhW7K9kKAPs34ArI9Zo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P34082 uniprotkb:Q5BIA5 intact:EBI-868243|uniprotkb:P34083|uniprotkb:Q8IRS5|uniprotkb:Q9W4M6|uniprotkb:Q6IDE4|ensemblmetazoa:FBpp0070633 intact:EBI-868238|ensemblmetazoa:FBpp0080364 psi-mi:fas2_drome(display_long)|uniprotkb:Fasciclin II(gene name synonym)|uniprotkb:Fas2(gene name)|psi-mi:Fas2(display_short)|uniprotkb:CG3665(orf name) psi-mi:q5bia5_drome(display_long)|uniprotkb:beat-Ia(gene name)|psi-mi:beat-Ia(display_short)|uniprotkb:CG4846(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871586 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_726911.1|refseq:NP_726912.1|flybase:FBgn0000635|refseq:NP_525066.1|ensemblmetazoa:FBgn0000635(gene)|ensemblmetazoa:FBtr0070665(transcript)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008038"(neuron recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008355"(olfactory learning)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035158"(regulation of tube diameter, open tracheal system)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050808"(synapse organization)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0072553"(terminal button organization)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904800"(negative regulation of neuron remodeling)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009138(Neural cell adhesion)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179 flybase:FBgn0013433|ensemblmetazoa:FBgn0013433(gene)|ensemblmetazoa:FBtr0080806(transcript)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0007415"(defasciculation of motor neuron axon)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0016198"(axon choice point recognition) pubmed:9847240(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:QW5g1dqazQzsvEKXYHT1dPOJNjU7227 rogid:JjgSLabRLtNhPXqMKeN7YTmHD8w7227 intact-crc:836A767AE18404B0|rigid:lLKv0Fezhq+7aDiHLCQbzkxgdiE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20480 uniprotkb:Q24560 intact:EBI-84482|uniprotkb:Q9VAG8|ensemblmetazoa:FBpp0084900|ensemblmetazoa:FBpp0311231 intact:EBI-152891|uniprotkb:Q53YG6|uniprotkb:Q9V8V4|ensemblmetazoa:FBpp0085720 psi-mi:ncd_drome(display_long)|uniprotkb:ncd(gene name)|psi-mi:ncd(display_short)|uniprotkb:"CA(ND)"(gene name synonym)|uniprotkb:CG7831(orf name) psi-mi:tbb1_drome(display_long)|uniprotkb:betaTub56D(gene name)|psi-mi:betaTub56D(display_short)|uniprotkb:CG9277(orf name)|uniprotkb:Beta-1-tubulin(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871590 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0031534"(minus-end directed microtubule sliding)|go:"GO:0032837"(distributive segregation)|ensemblmetazoa:FBtr0344976(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0072687"(meiotic spindle)|ensemblmetazoa:FBgn0002924(gene)|ensemblmetazoa:FBtr0085534(transcript)|rcsb pdb:3U06|rcsb pdb:5HLE|rcsb pdb:5HNW|rcsb pdb:5HNX|rcsb pdb:5HNY|rcsb pdb:5HNZ|rcsb pdb:5W3D|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:1CZ7|rcsb pdb:1N6M|rcsb pdb:1OZX|rcsb pdb:1SYJ|rcsb pdb:1SYP|rcsb pdb:1SZ4|rcsb pdb:1SZ5|rcsb pdb:2NCD|rcsb pdb:3L1C|refseq:NP_476651.1|flybase:FBgn0002924|refseq:NP_001287592.1|dip:DIP-21302N flybase:FBgn0284243|refseq:NP_523795.2|ensemblmetazoa:FBgn0284243(gene)|ensemblmetazoa:FBtr0086536(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q24560|rcsb pdb:6TIS|rcsb pdb:6TIU|rcsb pdb:6TIY|reactome:R-DME-3371497|reactome:R-DME-5620924|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811436|reactome:R-DME-983189|rcsb pdb:6TIZ|dip:DIP-43956N pubmed:7597061(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8sydvdYOvP3j1aqufTIH/rvDyJw7227 rogid:W2ZpMbiBVU1pKOu+VtC3ER8IMoc7227 intact-crc:5C12DCACE34FAFF3|rigid:X2hjXM2iGESekc7P1zFQhi4+d+c false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P17210 uniprotkb:Q24560 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 intact:EBI-152891|uniprotkb:Q53YG6|uniprotkb:Q9V8V4|ensemblmetazoa:FBpp0085720 psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:tbb1_drome(display_long)|uniprotkb:betaTub56D(gene name)|psi-mi:betaTub56D(display_short)|uniprotkb:CG9277(orf name)|uniprotkb:Beta-1-tubulin(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871594 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N flybase:FBgn0284243|refseq:NP_523795.2|ensemblmetazoa:FBgn0284243(gene)|ensemblmetazoa:FBtr0086536(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q24560|rcsb pdb:6TIS|rcsb pdb:6TIU|rcsb pdb:6TIY|reactome:R-DME-3371497|reactome:R-DME-5620924|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811436|reactome:R-DME-983189|rcsb pdb:6TIZ|dip:DIP-43956N pubmed:7597061(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 rogid:W2ZpMbiBVU1pKOu+VtC3ER8IMoc7227 intact-crc:463684B8EAC9522B|rigid:Zo3bu4RYw0Aj2lhmkj7YbbBv7Nk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7K4Z4 uniprotkb:Q9V3B4 intact:EBI-159623|ensemblmetazoa:FBpp0085904|ensemblmetazoa:FBpp0311815|intact:EBI-868295|uniprotkb:Q9NHG0 intact:EBI-104309|intact:EBI-1631809|uniprotkb:A4V9R6|uniprotkb:A4V9R7|uniprotkb:A4V9R5|ensemblmetazoa:FBpp0083574 psi-mi:imd_drome(display_long)|uniprotkb:imd(gene name)|psi-mi:imd(display_short)|uniprotkb:CG5576(orf name) psi-mi:fadd_drome(display_long)|uniprotkb:Fadd(gene name)|psi-mi:Fadd(display_short)|uniprotkb:BG4(gene name synonym)|uniprotkb:Death domain-containing adapter protein BG4(gene name synonym)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:CG12297(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871598 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_573394.1|flybase:FBgn0013983|ensemblmetazoa:FBgn0013983(gene)|ensemblmetazoa:FBtr0086725(transcript)|ensemblmetazoa:FBtr0345891(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0006959"(humoral immune response)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0006964"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0007399"(nervous system development)|go:"GO:0009617"(response to bacterium)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0070513"(death domain binding)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|reactome:R-DME-214397|reactome:R-DME-214399|reactome:R-DME-214411|reactome:R-DME-214416|go:"GO:0002803"(positive regulation of antibacterial peptide production)|refseq:NP_001286572.1 refseq:NP_651006.1|flybase:FBgn0038928|ensemblmetazoa:FBgn0038928(gene)|ensemblmetazoa:FBtr0084176(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005123"(death receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0089720"(caspase binding)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|reactome:R-DME-214397|reactome:R-DME-214399|reactome:R-DME-214411|reactome:R-DME-214416|dip:DIP-18912N pubmed:12433364(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2018/10/11 rogid:oMSiOYXo1NQuCDvy+j9OczmCuaI7227 rogid:TD97aEJUqLIypZRYRBB7gttIcaU7227 intact-crc:F3872166D55F4182|rigid:iGWNxFsRxBSBpN6W1LawYagbbsY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8IRY7 uniprotkb:Q9V3B4 intact:EBI-442182|ensemblmetazoa:FBpp0113052|uniprotkb:O02433|uniprotkb:O76797|uniprotkb:O76798|uniprotkb:Q95T94|uniprotkb:Q9UB42|uniprotkb:Q9W5E3 intact:EBI-104309|intact:EBI-1631809|uniprotkb:A4V9R6|uniprotkb:A4V9R7|uniprotkb:A4V9R5|ensemblmetazoa:FBpp0083574 psi-mi:casp8_drome(display_long)|uniprotkb:Death-related ced-3/NEDD2-like protein(gene name synonym)|uniprotkb:Dredd(gene name)|psi-mi:Dredd(display_short)|uniprotkb:DCP2(gene name synonym)|uniprotkb:CG7486(orf name) psi-mi:fadd_drome(display_long)|uniprotkb:Fadd(gene name)|psi-mi:Fadd(display_short)|uniprotkb:BG4(gene name synonym)|uniprotkb:Death domain-containing adapter protein BG4(gene name synonym)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:CG12297(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871602 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0020381(gene)|ensemblmetazoa:FBtr0114560(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0006955"(immune response)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0006964"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0007291"(sperm individualization)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0016485"(protein processing)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|reactome:R-DME-198323|reactome:R-DME-214397|reactome:R-DME-214399|reactome:R-DME-214411|reactome:R-DME-214416|reactome:R-DME-448706|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|flybase:FBgn0020381|refseq:NP_477249.3|refseq:NP_477250.3|refseq:NP_477251.3 refseq:NP_651006.1|flybase:FBgn0038928|ensemblmetazoa:FBgn0038928(gene)|ensemblmetazoa:FBtr0084176(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005123"(death receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0089720"(caspase binding)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|reactome:R-DME-214397|reactome:R-DME-214399|reactome:R-DME-214411|reactome:R-DME-214416|dip:DIP-18912N pubmed:10934188(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8VF2wS5q6ZXJbm/BlLH8aUFz9bw7227 rogid:TD97aEJUqLIypZRYRBB7gttIcaU7227 intact-crc:21A10F6DE24A56F2|rigid:IXMMZZKKGXQy3dRTCkj98TcD+gQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P22814 uniprotkb:Q24040 intact:EBI-868309|uniprotkb:A0AVT9|uniprotkb:O76551|uniprotkb:Q6SD78|uniprotkb:Q7KPD6|uniprotkb:Q8MRF4|uniprotkb:Q9TVG1|uniprotkb:Q9TVZ7|uniprotkb:Q9TZQ9|uniprotkb:Q9TZR0|uniprotkb:Q9VRB6|intact:EBI-1639673|ensemblmetazoa:FBpp0076971|ensemblmetazoa:FBpp0311837 intact:EBI-136112|intact:EBI-1629706|uniprotkb:Q95TG4|uniprotkb:Q9W0B9|ensemblmetazoa:FBpp0072641 psi-mi:runt_drome(display_long)|uniprotkb:run(gene name)|psi-mi:run(display_short)|uniprotkb:CG1849(orf name) psi-mi:bgb_drome(display_long)|uniprotkb:Bgb(gene name)|psi-mi:Bgb(display_short)|uniprotkb:CG7959(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871606 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001285501.1|refseq:NP_523424.2|flybase:FBgn0003300|ensemblmetazoa:FBgn0003300(gene)|ensemblmetazoa:FBtr0077279(transcript)|ensemblmetazoa:FBtr0345922(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007377"(germ-band extension)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007419"(ventral cord development)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048592"(eye morphogenesis)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|reactome:R-DME-549127|reactome:R-DME-8878166|reactome:R-DME-8931987|reactome:R-DME-8934593|reactome:R-DME-8936459|reactome:R-DME-8939236|reactome:R-DME-8939243|reactome:R-DME-8939245|reactome:R-DME-8939246|reactome:R-DME-8939247|reactome:R-DME-8939902|reactome:R-DME-8940973|reactome:R-DME-8941326|reactome:R-DME-9018519 refseq:NP_477065.3|flybase:FBgn0013753|ensemblmetazoa:FBgn0013753(gene)|ensemblmetazoa:FBtr0072758(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-DME-8931987|reactome:R-DME-8934593|go:"GO:0008134"(transcription factor binding)|reactome:R-DME-8936459|reactome:R-DME-8939236|go:"GO:0016513"(core-binding factor complex)|go:"GO:0035206"(regulation of hemocyte proliferation)|reactome:R-DME-8939243|interpro:IPR003417(Core binding factor, beta subunit)|reactome:R-DME-8939245|reactome:R-DME-8939246|reactome:R-DME-8939247|interpro:IPR036552|reactome:R-DME-8878166|reactome:R-DME-8941326|reactome:R-DME-8941858|reactome:R-DME-8951936|reactome:R-DME-9018519|dip:DIP-22891N pubmed:9077443(see-also)|pubmed:10393111(see-also)|pubmed:8622696(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:AhHjibxAU093Edu1nQPWbMTKGFo7227 rogid:hkF6uzA4PWioYF1W4mK3bAU4EnM7227 intact-crc:A078D76172356607|rigid:NIL8Hmny60sfl7yHbn+cldBFL0s false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9W349 uniprotkb:Q24040 intact:EBI-102646|uniprotkb:Q24183|uniprotkb:Q9NHX9|ensemblmetazoa:FBpp0071255 intact:EBI-136112|intact:EBI-1629706|uniprotkb:Q95TG4|uniprotkb:Q9W0B9|ensemblmetazoa:FBpp0072641 psi-mi:lozen_drome(display_long)|uniprotkb:lz(gene name)|psi-mi:lz(display_short)|uniprotkb:CG1689(orf name) psi-mi:bgb_drome(display_long)|uniprotkb:Bgb(gene name)|psi-mi:Bgb(display_short)|uniprotkb:CG7959(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871610 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511099.2|flybase:FBgn0002576|ensemblmetazoa:FBgn0002576(gene)|ensemblmetazoa:FBtr0071320(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007469"(antennal development)|go:"GO:0007486"(imaginal disc-derived female genitalia development)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035163"(embryonic hemocyte differentiation)|go:"GO:0035165"(embryonic crystal cell differentiation)|go:"GO:0035168"(larval lymph gland hemocyte differentiation)|go:"GO:0035211"(spermathecum morphogenesis)|go:"GO:0035314"(scab formation)|go:"GO:0042060"(wound healing)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045467"(R7 cell development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048592"(eye morphogenesis)|go:"GO:0048749"(compound eye development)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|reactome:R-DME-549127|reactome:R-DME-8878166|reactome:R-DME-8931987|reactome:R-DME-8934593|reactome:R-DME-8936459|reactome:R-DME-8939236|reactome:R-DME-8939243|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-DME-8939246|reactome:R-DME-8939247|reactome:R-DME-8939245|reactome:R-DME-8939902|reactome:R-DME-8940973|reactome:R-DME-8941326|reactome:R-DME-9018519 refseq:NP_477065.3|flybase:FBgn0013753|ensemblmetazoa:FBgn0013753(gene)|ensemblmetazoa:FBtr0072758(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-DME-8931987|reactome:R-DME-8934593|go:"GO:0008134"(transcription factor binding)|reactome:R-DME-8936459|reactome:R-DME-8939236|go:"GO:0016513"(core-binding factor complex)|go:"GO:0035206"(regulation of hemocyte proliferation)|reactome:R-DME-8939243|interpro:IPR003417(Core binding factor, beta subunit)|reactome:R-DME-8939245|reactome:R-DME-8939246|reactome:R-DME-8939247|interpro:IPR036552|reactome:R-DME-8878166|reactome:R-DME-8941326|reactome:R-DME-8941858|reactome:R-DME-8951936|reactome:R-DME-9018519|dip:DIP-22891N pubmed:11526071(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:y0EC6Q0MIEnXPovp3SsUU8JOQSY7227 rogid:hkF6uzA4PWioYF1W4mK3bAU4EnM7227 intact-crc:FE76385C51595547|rigid:qC9ZWhIsgw8erW0K1At2hh0ouRg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08928 uniprotkb:P16568 intact:EBI-188444|uniprotkb:Q9VMQ0|ensemblmetazoa:FBpp0078733|ensemblmetazoa:FBpp0297901|ensemblmetazoa:FBpp0297902|ensemblmetazoa:FBpp0312110 intact:EBI-112159|uniprotkb:Q9VJD5|intact:EBI-3433281|ensemblmetazoa:FBpp0080555|ensemblmetazoa:FBpp0303258 psi-mi:lam0_drome(display_long)|uniprotkb:Lam(gene name)|psi-mi:Lam(display_short)|uniprotkb:CG6944(orf name) psi-mi:bicd_drome(display_long)|uniprotkb:BicD(gene name)|psi-mi:BicD(display_short)|uniprotkb:CG6605(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871614 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476616.1|flybase:FBgn0002525|refseq:NP_001245892.1|refseq:NP_001245893.1|refseq:NP_001285629.1|dip:DIP-2663N|ensemblmetazoa:FBgn0002525(gene)|ensemblmetazoa:FBtr0079100(transcript)|ensemblmetazoa:FBtr0307058(transcript)|ensemblmetazoa:FBtr0307059(transcript)|ensemblmetazoa:FBtr0346460(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007097"(nuclear migration)|go:"GO:0007110"(meiosis I cytokinesis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007569"(cell aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0048137"(spermatocyte division)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:2000433"(positive regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-DME-352238|reactome:R-DME-4419969|reactome:R-DME-9013405|reactome:R-DME-9035034 refseq:NP_724056.1|flybase:FBgn0000183|dip:DIP-21297N|refseq:NP_001260530.1|ensemblmetazoa:FBgn0000183(gene)|ensemblmetazoa:FBtr0081002(transcript)|ensemblmetazoa:FBtr0330225(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007312"(oocyte nucleus migration involved in oocyte dorsal/ventral axis specification)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034452"(dynactin binding)|go:"GO:0048477"(oogenesis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050658"(RNA transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070727"(cellular macromolecule localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072393"(microtubule anchoring at microtubule organizing center)|go:"GO:0098793"(presynapse)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR018477|rcsb pdb:4BL6|rcsb pdb:6TZW|reactome:R-DME-6811436 pubmed:10350216(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Kuv16J8T6uZ7lIJaqjVrdn9x5WU7227 rogid:m/b6tkHAUFsgW+rqTrrD31dct687227 intact-crc:90E0378669EB1CDF|rigid:THet7I5amH8GUhBIehplgMj0s1E false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P92030 uniprotkb:P16568 intact:EBI-868335 intact:EBI-112159|uniprotkb:Q9VJD5|intact:EBI-3433281|ensemblmetazoa:FBpp0080555|ensemblmetazoa:FBpp0303258 psi-mi:p92030_drome(display_long)|uniprotkb:egl(gene name)|psi-mi:egl(display_short)|uniprotkb:CG4051(orf name) psi-mi:bicd_drome(display_long)|uniprotkb:BicD(gene name)|psi-mi:BicD(display_short)|uniprotkb:CG6605(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871618 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0000562|go:"GO:0003729"(mRNA binding)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007312"(oocyte nucleus migration involved in oocyte dorsal/ventral axis specification)|go:"GO:0007436"(larval salivary gland morphogenesis)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0045450"(bicoid mRNA localization)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046011"(regulation of oskar mRNA translation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold) refseq:NP_724056.1|flybase:FBgn0000183|dip:DIP-21297N|refseq:NP_001260530.1|ensemblmetazoa:FBgn0000183(gene)|ensemblmetazoa:FBtr0081002(transcript)|ensemblmetazoa:FBtr0330225(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007312"(oocyte nucleus migration involved in oocyte dorsal/ventral axis specification)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034452"(dynactin binding)|go:"GO:0048477"(oogenesis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050658"(RNA transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070727"(cellular macromolecule localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072393"(microtubule anchoring at microtubule organizing center)|go:"GO:0098793"(presynapse)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR018477|rcsb pdb:4BL6|rcsb pdb:6TZW|reactome:R-DME-6811436 pubmed:10655224(see-also)|pubmed:9042857(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:qrjbYygh2JYp/M4JUj5ELNC1w8Y7227 rogid:m/b6tkHAUFsgW+rqTrrD31dct687227 intact-crc:FEC2B2BC02B9010F|rigid:oWSrcTDKCwuXCzTzv+oCpfDXZ6M false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16568 uniprotkb:P16568 intact:EBI-112159|uniprotkb:Q9VJD5|intact:EBI-3433281|ensemblmetazoa:FBpp0080555|ensemblmetazoa:FBpp0303258 intact:EBI-112159|uniprotkb:Q9VJD5|intact:EBI-3433281|ensemblmetazoa:FBpp0080555|ensemblmetazoa:FBpp0303258 psi-mi:bicd_drome(display_long)|uniprotkb:BicD(gene name)|psi-mi:BicD(display_short)|uniprotkb:CG6605(orf name) psi-mi:bicd_drome(display_long)|uniprotkb:BicD(gene name)|psi-mi:BicD(display_short)|uniprotkb:CG6605(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871622 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_724056.1|flybase:FBgn0000183|dip:DIP-21297N|refseq:NP_001260530.1|ensemblmetazoa:FBgn0000183(gene)|ensemblmetazoa:FBtr0081002(transcript)|ensemblmetazoa:FBtr0330225(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007312"(oocyte nucleus migration involved in oocyte dorsal/ventral axis specification)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034452"(dynactin binding)|go:"GO:0048477"(oogenesis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050658"(RNA transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070727"(cellular macromolecule localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072393"(microtubule anchoring at microtubule organizing center)|go:"GO:0098793"(presynapse)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR018477|rcsb pdb:4BL6|rcsb pdb:6TZW|reactome:R-DME-6811436 refseq:NP_724056.1|flybase:FBgn0000183|dip:DIP-21297N|refseq:NP_001260530.1|ensemblmetazoa:FBgn0000183(gene)|ensemblmetazoa:FBtr0081002(transcript)|ensemblmetazoa:FBtr0330225(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007312"(oocyte nucleus migration involved in oocyte dorsal/ventral axis specification)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034452"(dynactin binding)|go:"GO:0048477"(oogenesis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050658"(RNA transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070727"(cellular macromolecule localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072393"(microtubule anchoring at microtubule organizing center)|go:"GO:0098793"(presynapse)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR018477|rcsb pdb:4BL6|rcsb pdb:6TZW|reactome:R-DME-6811436 pubmed:10655224(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:m/b6tkHAUFsgW+rqTrrD31dct687227 rogid:m/b6tkHAUFsgW+rqTrrD31dct687227 intact-crc:4B8FC453BDC9C24D|rigid:Reuc9nkpRYo3h99Z+4REXiYQsms false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P12982 uniprotkb:O16125 intact:EBI-152633|uniprotkb:Q4PIY5|uniprotkb:Q9VG75|ensemblmetazoa:FBpp0082067 intact:EBI-868347 psi-mi:pp12_drome(display_long)|uniprotkb:Pp1-87B(gene name)|psi-mi:Pp1-87B(display_short)|uniprotkb:CG5650(orf name) psi-mi:o16125_drome(display_long)|uniprotkb:bif(gene name)|psi-mi:bif(display_short)|uniprotkb:bifocal(gene name synonym)|uniprotkb:CG1822(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871626 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524937.1|flybase:FBgn0004103|ensemblmetazoa:FBgn0004103(gene)|ensemblmetazoa:FBtr0082595(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007611"(learning or memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008355"(olfactory learning)|go:"GO:0008542"(visual learning)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030261"(chromosome condensation)|go:"GO:0040011"(locomotion)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|go:"GO:0005737"(cytoplasm)|reactome:R-DME-350416|reactome:R-DME-350480|reactome:R-DME-538898|go:"GO:0005700"(polytene chromosome)|dip:DIP-18465N flybase:FBgn0014133|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006935"(chemotaxis)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051015"(actin filament binding)|interpro:IPR019130 pubmed:11238949(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:wYZDYWZEbdafO7gAM+avnFnIF9Q7227 rogid:62JxwEPee30fRwz0Qy4EWxAbMfY7227 intact-crc:FD3F2C86B403F6D6|rigid:c4M+AQdLorT/da1tvmuildk09GU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KV88 uniprotkb:O16125 intact:EBI-868359|ensemblmetazoa:FBpp0089311|ensemblmetazoa:FBpp0089312 intact:EBI-868347 psi-mi:q7kv88_drome(display_long)|uniprotkb:CG16973-RD(gene name synonym)|uniprotkb:CG16973(orf name)|uniprotkb:msn(gene name)|psi-mi:msn(display_short)|uniprotkb:6286(gene name synonym)|uniprotkb:DMSN(gene name synonym)|uniprotkb:Dmel\CG16973(gene name synonym)|uniprotkb:HGK(gene name synonym)|uniprotkb:JNKKKK(gene name synonym)|uniprotkb:MESR5(gene name synonym)|uniprotkb:MSN(gene name synonym)|uniprotkb:Msn(gene name synonym)|uniprotkb:NIK(gene name synonym)|uniprotkb:Nik(gene name synonym)|uniprotkb:"l(3)03349"(gene name synonym)|uniprotkb:"l(3)06946"(gene name synonym)|uniprotkb:"l(3)6286"(gene name synonym)|uniprotkb:"l(3)j1E2"(gene name synonym)|uniprotkb:msm(gene name synonym)|uniprotkb:Dmel_CG16973(orf name) psi-mi:o16125_drome(display_long)|uniprotkb:bif(gene name)|psi-mi:bif(display_short)|uniprotkb:bifocal(gene name synonym)|uniprotkb:CG1822(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871630 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_995972.1|refseq:NP_995973.1|flybase:FBgn0010909|ensemblmetazoa:FBtr0072958(transcript)|ensemblmetazoa:FBtr0072959(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001748"(insect visual primordium development)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007097"(nuclear migration)|go:"GO:0007254"(JNK cascade)|go:"GO:0007391"(dorsal closure)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009611"(response to wounding)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042656"(JUN kinase kinase kinase kinase activity)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR021160|ensemblmetazoa:FBgn0010909(gene) flybase:FBgn0014133|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006935"(chemotaxis)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051015"(actin filament binding)|interpro:IPR019130 pubmed:12467587(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:rcJvSCSw3DtAy5Tu69AYlOm0O6c7227 rogid:62JxwEPee30fRwz0Qy4EWxAbMfY7227 intact-crc:B6C627E35D4A2458|rigid:bOpZx+cPiqY2Q9cHydIMAigINVA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P48810 uniprotkb:Q7KA80 intact:EBI-93570|uniprotkb:Q24486|uniprotkb:Q8INH0|uniprotkb:Q9VFT2|ensemblmetazoa:FBpp0082316|ensemblmetazoa:FBpp0289817|ensemblmetazoa:FBpp0302741|ensemblmetazoa:FBpp0306562 intact:EBI-868377 psi-mi:rb87f_drome(display_long)|uniprotkb:Hrb87F(gene name)|psi-mi:Hrb87F(display_short)|uniprotkb:hrp36(gene name synonym)|uniprotkb:HRP36.1 protein(gene name synonym)|uniprotkb:Protein P11(gene name synonym)|uniprotkb:CG12749(orf name) psi-mi:q7ka80_drome(display_long)|uniprotkb:HnRNP-K(gene name)|psi-mi:HnRNP-K(display_short)|uniprotkb:Hrb57A(gene name synonym)|uniprotkb:bl(gene name synonym)|uniprotkb:CG13425(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871642 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163602.1|refseq:NP_476807.1|flybase:FBgn0004237|ensemblmetazoa:FBgn0004237(gene)|ensemblmetazoa:FBtr0082851(transcript)|ensemblmetazoa:FBtr0300590(transcript)|ensemblmetazoa:FBtr0310621(transcript)|ensemblmetazoa:FBtr0334495(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008585"(female gonad development)|go:"GO:0009408"(response to heat)|go:"GO:0034046"("poly(G) binding")|go:"GO:0035062"(omega speckle)|go:"GO:0042594"(response to starvation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0000785"(chromatin)|refseq:NP_001262538.1|refseq:NP_476806.2 flybase:FBgn0267791|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035062"(omega speckle)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612 pubmed:10713453(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:0/zJfq5ck29psI8dANCI0L9/Qbw7227 rogid:99sEgnovHQXZt8sID4M4pyF/ZLA7227 intact-crc:8AC3511C1BA8A3DF|rigid:VcLLXAbPzJi2UUuEqwMQTuwF28U false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q09147 uniprotkb:P91672 intact:EBI-122593|uniprotkb:A4V1Y3|uniprotkb:Q712V2|uniprotkb:Q9VUC8|ensemblmetazoa:FBpp0075520|ensemblmetazoa:FBpp0100143 intact:EBI-868411|ensemblmetazoa:FBpp0083206 psi-mi:fgfr2_drome(display_long)|uniprotkb:FR2(gene name synonym)|uniprotkb:HD-311(gene name synonym)|uniprotkb:Protein breathless(gene name synonym)|uniprotkb:Tk2(gene name synonym)|uniprotkb:Tyrosine kinase 2(gene name synonym)|uniprotkb:Tyrosine kinase receptor HD-311(gene name synonym)|uniprotkb:CG32134(orf name)|uniprotkb:btl(gene name)|psi-mi:btl(display_short)|uniprotkb:dFGF-R1(gene name synonym) psi-mi:p91672_drome(display_long)|uniprotkb:bnl(gene name)|psi-mi:bnl(display_short)|uniprotkb:branchless(gene name synonym)|uniprotkb:CG4608(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871646 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014583.1|refseq:NP_729956.1|ensemblmetazoa:FBgn0285896(gene)|ensemblmetazoa:FBtr0075778(transcript)|ensemblmetazoa:FBtr0100676(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005007"(fibroblast growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007428"(primary branching, open tracheal system)|go:"GO:0007429"(secondary branching, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035008"(positive regulation of melanization defense response)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035154"(terminal cell fate specification, open tracheal system)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035215"(genital disc development)|go:"GO:0035230"(cytoneme)|go:"GO:0042690"(negative regulation of crystal cell differentiation)|go:"GO:0043235"(receptor complex)|go:"GO:0045614"(negative regulation of plasmatocyte differentiation)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0060438"(trachea development)|reactome:R-DME-5654719|reactome:R-DME-5654720|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5654733|reactome:R-DME-5673001|reactome:R-DME-6811558|go:"GO:0060446"(branching involved in open tracheal system development)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR000719(Protein kinase, core)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036179|reactome:R-DME-109704|reactome:R-DME-1257604|reactome:R-DME-1307965|reactome:R-DME-190322|reactome:R-DME-190370|reactome:R-DME-190371|reactome:R-DME-190372|reactome:R-DME-190373|reactome:R-DME-190374|reactome:R-DME-190375|reactome:R-DME-190377|reactome:R-DME-5654219|reactome:R-DME-5654221|reactome:R-DME-5654227|reactome:R-DME-5654228|reactome:R-DME-5654687|reactome:R-DME-5654688|reactome:R-DME-5654689|reactome:R-DME-5654693|reactome:R-DME-5654695|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654710|reactome:R-DME-5654712|flybase:FBgn0285896 flybase:FBgn0014135|ensemblmetazoa:FBgn0014135(gene)|ensemblmetazoa:FBtr0083795(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0035215"(genital disc development)|go:"GO:0035231"(cytoneme assembly)|go:"GO:0046847"(filopodium assembly)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like) pubmed:8978613(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8Gq7DGFh9sr1Aa+42t2KqlK+a687227 rogid:oPKto5GcEk1iQjRfNuyFFUOzNjQ7227 intact-crc:EFE0486BDB9C03D3|rigid:Wh34XXvQXAj7MC2IQVJKsj/4eXE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P33244 uniprotkb:Q9U3Y7 intact:EBI-160447|ensemblmetazoa:FBpp0074853|uniprotkb:Q24538|uniprotkb:Q8IQT5|uniprotkb:Q960U2|uniprotkb:Q9VVS8|uniprotkb:B9EQU1 intact:EBI-499050 psi-mi:ftzf1_drome(display_long)|uniprotkb:ftz-f1(gene name)|psi-mi:ftz-f1(display_short)|uniprotkb:NR5A3(gene name synonym)|uniprotkb:CG4059(orf name)|uniprotkb:FTZ-F1 alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 5 group A member 3(gene name synonym) psi-mi:q9u3y7_drome(display_long)|uniprotkb:CG5206(orf name)|uniprotkb:bon(gene name)|psi-mi:bon(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871650 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524143.2|refseq:NP_730359.1|flybase:FBgn0001078|ensemblmetazoa:FBgn0001078(gene)|ensemblmetazoa:FBtr0075086(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002165"(instar larval or pupal development)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007552"(metamorphosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008219"(cell death)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009888"(tissue development)|go:"GO:0016319"(mushroom body development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0035073"(pupariation)|go:"GO:0035074"(pupation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035626"(juvenile hormone mediated signaling pathway)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016355(Orphan nuclear receptor Fushi-tarazu factor 1)|interpro:IPR035500|rcsb pdb:2XHS|reactome:R-DME-383280|reactome:R-DME-4090294|refseq:NP_001246824.1 flybase:FBgn0023097|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|go:"GO:0006325"(chromatin organization)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427 pubmed:11336699(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:m/yxQjjm37/IaCCpLPpZFwPPV+c7227 rogid:vqXkbcFHZmRKHFlbqn03YSad+jY7227 intact-crc:1B3F102F2A0DBE1E|rigid:w9zw0sSAyfukMORkX99X8VL/UmE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P13368 uniprotkb:P22815 intact:EBI-522166|uniprotkb:Q9TYI0|uniprotkb:Q9U5V7|uniprotkb:Q9VZ36|ensemblmetazoa:FBpp0073249 intact:EBI-185621|uniprotkb:Q9VBJ5|ensemblmetazoa:FBpp0084323 psi-mi:7less_drome(display_long)|uniprotkb:sev(gene name)|psi-mi:sev(display_short)|uniprotkb:HD-265(gene name synonym)|uniprotkb:CG18085(orf name) psi-mi:boss_drome(display_long)|uniprotkb:boss(gene name)|psi-mi:boss(display_short)|uniprotkb:CG8285(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871654 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511114.2|flybase:FBgn0003366|ensemblmetazoa:FBgn0003366(gene)|go:"GO:0045500"(sevenless signaling pathway)|ensemblmetazoa:FBtr0073393(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008288"(boss receptor activity)|go:"GO:0019199"(transmembrane receptor protein kinase activity)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0043235"(receptor complex)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116 refseq:NP_542440.1|flybase:FBgn0000206|ensemblmetazoa:FBgn0000206(gene)|ensemblmetazoa:FBtr0084949(transcript)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0005118"(sevenless binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0009749"(response to glucose)|go:"GO:0035997"(rhabdomere microvillus membrane)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045470"(R8 cell-mediated photoreceptor organization)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099530"(G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|interpro:IPR002956(Bride of sevenless protein)|interpro:IPR017978 pubmed:1857416(see-also)|pubmed:7680109(see-also)|pubmed:1316239(see-also)|pubmed:9472002(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:YpmSTbTsxz1LSM+oNtflAISXkIQ7227 rogid:u7JKNxPVUqmuPB3h5mPU46lUE0A7227 intact-crc:25E764D0F1137AFB|rigid:WCP4+BiIauEnhCPvRg6mySf3Hqo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P25822 uniprotkb:Q8MQJ9 intact:EBI-252055|uniprotkb:A4V2K5|uniprotkb:Q5BIA7|uniprotkb:Q7YU65|uniprotkb:Q9VHH4|uniprotkb:Q9VHH6|uniprotkb:Q8IGA8|ensemblmetazoa:FBpp0081470|ensemblmetazoa:FBpp0081471|ensemblmetazoa:FBpp0081472|ensemblmetazoa:FBpp0305823 intact:EBI-414123|ensemblmetazoa:FBpp0080702|ensemblmetazoa:FBpp0080703|ensemblmetazoa:FBpp0089239|ensemblmetazoa:FBpp0311161|uniprotkb:A4V0U9|uniprotkb:Q0E8P2|uniprotkb:Q2XXZ6|uniprotkb:Q8MR02|uniprotkb:Q9U633|uniprotkb:Q9U634|uniprotkb:Q9U635|uniprotkb:Q9U636|uniprotkb:Q9Y1W4 psi-mi:pum_drome(display_long)|uniprotkb:pum(gene name)|psi-mi:pum(display_short)|uniprotkb:CG9755(orf name) psi-mi:brat_drome(display_long)|uniprotkb:brat(gene name)|psi-mi:brat(display_short)|uniprotkb:CG10719(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871658 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524285.2|refseq:NP_731314.1|refseq:NP_731315.1|refseq:NP_731316.2|refseq:NP_788604.1|flybase:FBgn0003165|refseq:NP_001262403.1|ensemblmetazoa:FBgn0003165(gene)|ensemblmetazoa:FBtr0081990(transcript)|ensemblmetazoa:FBtr0081991(transcript)|ensemblmetazoa:FBtr0081992(transcript)|ensemblmetazoa:FBtr0333667(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007280"(pole cell migration)|go:"GO:0007281"(germ cell development)|go:"GO:0007616"(long-term memory)|go:"GO:0008258"(head involution)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0016477"(cell migration)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061177"(type Is terminal bouton)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901835"(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3H3D|rcsb pdb:5KL1|rcsb pdb:5KL8|rcsb pdb:5KLA|reactome:R-DME-432722 ensemblmetazoa:FBgn0010300(gene)|ensemblmetazoa:FBtr0081158(transcript)|ensemblmetazoa:FBtr0081159(transcript)|ensemblmetazoa:FBtr0081160(transcript)|ensemblmetazoa:FBtr0344846(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007402"(ganglion mother cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007419"(ventral cord development)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009303"(rRNA transcription)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014016"(neuroblast differentiation)|go:"GO:0014019"(neuroblast development)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030371"(translation repressor activity)|go:"GO:0035282"(segmentation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0045179"(apical cortex)|go:"GO:0045180"(basal cortex)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048477"(oogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0055060"(asymmetric neuroblast division resulting in ganglion mother cell formation)|go:"GO:0099738"(cell cortex region)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|rcsb pdb:1Q7F|rcsb pdb:4ZLR|rcsb pdb:5EX7|rcsb pdb:6J9R|refseq:NP_476945.1|refseq:NP_599129.1|refseq:NP_995726.1|flybase:FBgn0010300|refseq:NP_001286083.1|dip:DIP-37857N pubmed:11336677(see-also)|pubmed:14561773(see-also)|pubmed:11274060(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:z0jqCHqL2L2hUrWEa1pQiksf6hs7227 rogid:AK7/c4ZRqzMGYWhAS1cr9N2xjI07227 intact-crc:F21BC5B81A5D0497|rigid:/3c+BiMobRoUC8WIUjEIE7N4Hv4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P25724 uniprotkb:Q8MQJ9 intact:EBI-106556|uniprotkb:Q9VDZ6|ensemblmetazoa:FBpp0083146 intact:EBI-414123|ensemblmetazoa:FBpp0080702|ensemblmetazoa:FBpp0080703|ensemblmetazoa:FBpp0089239|ensemblmetazoa:FBpp0311161|uniprotkb:A4V0U9|uniprotkb:Q0E8P2|uniprotkb:Q2XXZ6|uniprotkb:Q8MR02|uniprotkb:Q9U633|uniprotkb:Q9U634|uniprotkb:Q9U635|uniprotkb:Q9U636|uniprotkb:Q9Y1W4 psi-mi:nanos_drome(display_long)|uniprotkb:nos(gene name)|psi-mi:nos(display_short)|uniprotkb:CG5637(orf name) psi-mi:brat_drome(display_long)|uniprotkb:brat(gene name)|psi-mi:brat(display_short)|uniprotkb:CG10719(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871662 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476658.1|flybase:FBgn0002962|dip:DIP-23696N|ensemblmetazoa:FBgn0002962(gene)|ensemblmetazoa:FBtr0083732(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007280"(pole cell migration)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035282"(segmentation)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045495"(pole plasm)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0098975"(postsynapse of neuromuscular junction)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR008705(Zinc finger, Nanos)|interpro:IPR024161|interpro:IPR038129|rcsb pdb:5KL1|rcsb pdb:5KL8 ensemblmetazoa:FBgn0010300(gene)|ensemblmetazoa:FBtr0081158(transcript)|ensemblmetazoa:FBtr0081159(transcript)|ensemblmetazoa:FBtr0081160(transcript)|ensemblmetazoa:FBtr0344846(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007402"(ganglion mother cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007419"(ventral cord development)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009303"(rRNA transcription)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014016"(neuroblast differentiation)|go:"GO:0014019"(neuroblast development)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030371"(translation repressor activity)|go:"GO:0035282"(segmentation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0045179"(apical cortex)|go:"GO:0045180"(basal cortex)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048477"(oogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0055060"(asymmetric neuroblast division resulting in ganglion mother cell formation)|go:"GO:0099738"(cell cortex region)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|rcsb pdb:1Q7F|rcsb pdb:4ZLR|rcsb pdb:5EX7|rcsb pdb:6J9R|refseq:NP_476945.1|refseq:NP_599129.1|refseq:NP_995726.1|flybase:FBgn0010300|refseq:NP_001286083.1|dip:DIP-37857N pubmed:11274060(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Odk9EPZ9mhtw2sC1379nInFonas7227 rogid:AK7/c4ZRqzMGYWhAS1cr9N2xjI07227 intact-crc:F0757DF797C045A6|rigid:kpX2XXUSAP70eenfJAO2eN6NrTU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9UAC5 uniprotkb:Q9NB72 intact:EBI-868447 intact:EBI-868433 psi-mi:q9uac5_drome(display_long)|uniprotkb:Traf4(gene name)|psi-mi:Traf4(display_short)|uniprotkb:traf1(gene name synonym)|uniprotkb:CG3048(orf name)|uniprotkb:Traf1(gene name synonym) psi-mi:q9nb72_drome(display_long)|uniprotkb:Brf(gene name)|psi-mi:Brf(display_short)|uniprotkb:CG31256(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871666 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0026319|go:"GO:0001654"(eye development)|go:"GO:0003384"(apical constriction involved in gastrulation)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|go:"GO:0034332"(adherens junction organization) flybase:FBgn0038499|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070897"(transcription preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR000812(Transcription factor TFIIB related)|interpro:IPR011665(Brf1-like TBP-binding)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR013150(Transcription factor TFIIB, cyclin-related)|interpro:IPR013763(Cyclin-related)|interpro:IPR029529|interpro:IPR036915 pubmed:10850489(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:I+bBjRvDZ/MnoA5YyVxty92NBzE7227 rogid:aMCJTHQ7rNwlzy0kXGEr7UQwzaU7227 intact-crc:A2C4A726ACDFB10A|rigid:Hx9EkhxLsDY0G1DawrFpJfJZX4c false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P22265 uniprotkb:Q960G9 intact:EBI-167288|uniprotkb:A8E6H0|uniprotkb:Q6AWP7|uniprotkb:Q7KRS3|uniprotkb:Q9V9Q0|ensemblmetazoa:FBpp0085261 intact:EBI-868466|ensemblmetazoa:FBpp0071007 psi-mi:tsh_drome(display_long)|uniprotkb:tsh(gene name)|psi-mi:tsh(display_short)|uniprotkb:CG1374(orf name) psi-mi:q960g9_drome(display_long)|uniprotkb:brk(gene name)|psi-mi:brk(display_short)|uniprotkb:CG9653(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871670 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0003866(gene)|ensemblmetazoa:FBtr0085906(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007380"(specification of segmental identity, head)|go:"GO:0007384"(specification of segmental identity, thorax)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007473"(wing disc proximal/distal pattern formation)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007494"(midgut development)|go:"GO:0008258"(head involution)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035292"(specification of segmental identity, trunk)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0005654"(nucleoplasm)|flybase:FBgn0003866|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0061330"(Malpighian tubule stellate cell differentiation)|go:"GO:2000497"(positive regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR026807|interpro:IPR027008|interpro:IPR036236|interpro:IPR041661|reactome:R-DME-390193|refseq:NP_523615.2 flybase:FBgn0024250|ensemblmetazoa:FBgn0024250(gene)|ensemblmetazoa:FBtr0071048(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061328"(posterior Malpighian tubule development) pubmed:12130542(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:4q9w9M/oqAa0jnzgXlKqVts2PBQ7227 rogid:EUEin4BIvh2ipNAz6MqWPSy9sY87227 intact-crc:D5353DA63FD42118|rigid:5cRWmaKIqV1oljb+0sybjMv4qmQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q960G9 uniprotkb:P16371 intact:EBI-868466|ensemblmetazoa:FBpp0071007 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:q960g9_drome(display_long)|uniprotkb:brk(gene name)|psi-mi:brk(display_short)|uniprotkb:CG9653(orf name) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871674 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0024250|ensemblmetazoa:FBgn0024250(gene)|ensemblmetazoa:FBtr0071048(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061328"(posterior Malpighian tubule development) refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N pubmed:11159907(see-also)|pubmed:11598015(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:EUEin4BIvh2ipNAz6MqWPSy9sY87227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 intact-crc:E3EBCF356E157AAF|rigid:7dgA5XUAC8BbeiPQc27x7Z3zDak false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O46036 uniprotkb:Q960G9 intact:EBI-159330|uniprotkb:O61283|uniprotkb:Q59DX5|ensemblmetazoa:FBpp0099514|uniprotkb:Q95SQ8|uniprotkb:Q9VG02 intact:EBI-868466|ensemblmetazoa:FBpp0071007 psi-mi:ctbp_drome(display_long)|uniprotkb:CtBP(gene name)|psi-mi:CtBP(display_short)|uniprotkb:CG7583(orf name)|uniprotkb:dCtBP(gene name synonym) psi-mi:q960g9_drome(display_long)|uniprotkb:brk(gene name)|psi-mi:brk(display_short)|uniprotkb:CG9653(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871678 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014617.1|refseq:NP_524336.2|refseq:NP_731762.1|refseq:NP_731763.1|refseq:NP_731764.1|flybase:FBgn0020496|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0022416"(chaeta development)|go:"GO:0031010"(ISWI-type complex)|go:"GO:0035220"(wing disc development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051287"(NAD binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:O46036|reactome:R-DME-3769402|go:"GO:0008134"(transcription factor binding)|ensemblmetazoa:FBgn0020496(gene)|ensemblmetazoa:FBtr0100161(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-DME-3899300|reactome:R-DME-4641265|refseq:NP_001262520.1|dip:DIP-17268N flybase:FBgn0024250|ensemblmetazoa:FBgn0024250(gene)|ensemblmetazoa:FBtr0071048(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061328"(posterior Malpighian tubule development) pubmed:11598015(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:hbMeldNlirFwVr+5QX9bGiPqZ1w7227 rogid:EUEin4BIvh2ipNAz6MqWPSy9sY87227 intact-crc:0EF535314103E005|rigid:VoanrVEeltdfxgBwKLHsPCM+enY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24090 uniprotkb:P25439 intact:EBI-151570|ensemblmetazoa:FBpp0078331 intact:EBI-868480|uniprotkb:Q9VUW5|uniprotkb:Q9VUW6|uniprotkb:A4V1Z7|uniprotkb:A4V1Z8|ensemblmetazoa:FBpp0075280|ensemblmetazoa:FBpp0075281 psi-mi:q24090_drome(display_long)|uniprotkb:Snr1(gene name)|psi-mi:Snr1(display_short)|uniprotkb:BAP45(gene name synonym)|uniprotkb:Dmel\CG1064(gene name synonym)|uniprotkb:SNR1(gene name synonym)|uniprotkb:Snr(gene name synonym)|uniprotkb:Snr-1(gene name synonym)|uniprotkb:"l(3)01319"(gene name synonym)|uniprotkb:snr(gene name synonym)|uniprotkb:snr-1(gene name synonym)|uniprotkb:snr1(gene name synonym)|uniprotkb:Dmel_CG1064(orf name)|uniprotkb:CG1064(orf name) psi-mi:brm_drome(display_long)|uniprotkb:Homeotic gene regulator(gene name synonym)|uniprotkb:Protein brahma(gene name synonym)|uniprotkb:brm(gene name)|psi-mi:brm(display_short)|uniprotkb:CG5942(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871682 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_730935.1|flybase:FBgn0011715|dip:DIP-17554N|ensemblmetazoa:FBgn0011715(gene)|ensemblmetazoa:FBtr0078682(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035060"(brahma complex)|go:"GO:0043044"|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070983"(dendrite guidance)|go:"GO:0070984"(SET domain binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|mint:Q24090|reactome:R-DME-3214858|reactome:R-DME-8939243 refseq:NP_730089.1|flybase:FBgn0000212|refseq:NP_730088.1|refseq:NP_536745.4|refseq:NP_536746.1|dip:DIP-36728N|ensemblmetazoa:FBgn0000212(gene)|ensemblmetazoa:FBtr0075525(transcript)|ensemblmetazoa:FBtr0075526(transcript)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007419"(ventral cord development)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0043974"(histone H3-K27 acetylation)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070615"|go:"GO:0070983"(dendrite guidance)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030088|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P25439|reactome:R-DME-1266695|reactome:R-DME-3214858|reactome:R-DME-3247509|reactome:R-DME-8939243 pubmed:7579694(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:fKg0O+kw3EfuBuHr8S9MQNxAugU7227 rogid:+pqTXhDIJ2DgEQoHQwnnBdat8kQ7227 intact-crc:AE8CA26DE66FE271|rigid:CpYbU00ttF6eJDo0IldLPUMB+/A false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8IN94 uniprotkb:P25439 intact:EBI-115993|uniprotkb:O61603|uniprotkb:Q9VEG7|ensemblmetazoa:FBpp0088543|ensemblmetazoa:FBpp0290702|intact:EBI-3432601 intact:EBI-868480|uniprotkb:Q9VUW5|uniprotkb:Q9VUW6|uniprotkb:A4V1Z7|uniprotkb:A4V1Z8|ensemblmetazoa:FBpp0075280|ensemblmetazoa:FBpp0075281 psi-mi:osa_drome(display_long)|uniprotkb:Protein eyelid(gene name synonym)|uniprotkb:CG7467(orf name)|uniprotkb:osa(gene name)|psi-mi:osa(display_short)|uniprotkb:eld(gene name synonym) psi-mi:brm_drome(display_long)|uniprotkb:Homeotic gene regulator(gene name synonym)|uniprotkb:Protein brahma(gene name synonym)|uniprotkb:brm(gene name)|psi-mi:brm(display_short)|uniprotkb:CG5942(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871686 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0261885(gene)|ensemblmetazoa:FBtr0089581(transcript)|ensemblmetazoa:FBtr0301487(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0071565"(nBAF complex)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021906|interpro:IPR033388|interpro:IPR036431|mint:Q8IN94|reactome:R-DME-3214858|reactome:R-DME-8939243|go:"GO:0043044"|refseq:NP_001163639.1|refseq:NP_524392.2|refseq:NP_732263.1|flybase:FBgn0261885|dip:DIP-20699N refseq:NP_730089.1|flybase:FBgn0000212|refseq:NP_730088.1|refseq:NP_536745.4|refseq:NP_536746.1|dip:DIP-36728N|ensemblmetazoa:FBgn0000212(gene)|ensemblmetazoa:FBtr0075525(transcript)|ensemblmetazoa:FBtr0075526(transcript)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007419"(ventral cord development)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0043974"(histone H3-K27 acetylation)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070615"|go:"GO:0070983"(dendrite guidance)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030088|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P25439|reactome:R-DME-1266695|reactome:R-DME-3214858|reactome:R-DME-3247509|reactome:R-DME-8939243 pubmed:9895321(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:2vTFF8lojmWu98YEVfc6DqXli/07227 rogid:+pqTXhDIJ2DgEQoHQwnnBdat8kQ7227 intact-crc:CC5FDAE2AE050FDD|rigid:LcyynaRvub2oQIJ7JN6mr0GBtQ8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KND4 uniprotkb:P25439 intact:EBI-868513|ensemblmetazoa:FBpp0291706 intact:EBI-868480|uniprotkb:Q9VUW5|uniprotkb:Q9VUW6|uniprotkb:A4V1Z7|uniprotkb:A4V1Z8|ensemblmetazoa:FBpp0075280|ensemblmetazoa:FBpp0075281 psi-mi:q7knd4_drome(display_long)|uniprotkb:mor(gene name)|psi-mi:mor(display_short)|uniprotkb:moira(gene name synonym)|uniprotkb:CG18740(orf name) psi-mi:brm_drome(display_long)|uniprotkb:Homeotic gene regulator(gene name synonym)|uniprotkb:Protein brahma(gene name synonym)|uniprotkb:brm(gene name)|psi-mi:brm(display_short)|uniprotkb:CG5942(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871690 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0002783|ensemblmetazoa:FBgn0002783(gene)|ensemblmetazoa:FBtr0302550(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR032450 refseq:NP_730089.1|flybase:FBgn0000212|refseq:NP_730088.1|refseq:NP_536745.4|refseq:NP_536746.1|dip:DIP-36728N|ensemblmetazoa:FBgn0000212(gene)|ensemblmetazoa:FBtr0075525(transcript)|ensemblmetazoa:FBtr0075526(transcript)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007419"(ventral cord development)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0043974"(histone H3-K27 acetylation)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070615"|go:"GO:0070983"(dendrite guidance)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030088|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P25439|reactome:R-DME-1266695|reactome:R-DME-3214858|reactome:R-DME-3247509|reactome:R-DME-8939243 pubmed:9891050(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NIID+nUemxYqyVHHGGKKXRz9nRo7227 rogid:+pqTXhDIJ2DgEQoHQwnnBdat8kQ7227 intact-crc:0F96C26A773C5B35|rigid:qUTVTD56Hj+DXkmeR4GQEe4mHSs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q961D0 uniprotkb:P25439 intact:EBI-868519 intact:EBI-868480|uniprotkb:Q9VUW5|uniprotkb:Q9VUW6|uniprotkb:A4V1Z7|uniprotkb:A4V1Z8|ensemblmetazoa:FBpp0075280|ensemblmetazoa:FBpp0075281 psi-mi:q961d0_drome(display_long)|uniprotkb:dalao(gene name)|psi-mi:dalao(display_short) psi-mi:brm_drome(display_long)|uniprotkb:Homeotic gene regulator(gene name synonym)|uniprotkb:Protein brahma(gene name synonym)|uniprotkb:brm(gene name)|psi-mi:brm(display_short)|uniprotkb:CG5942(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871694 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030089|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0043044" refseq:NP_730089.1|flybase:FBgn0000212|refseq:NP_730088.1|refseq:NP_536745.4|refseq:NP_536746.1|dip:DIP-36728N|ensemblmetazoa:FBgn0000212(gene)|ensemblmetazoa:FBtr0075525(transcript)|ensemblmetazoa:FBtr0075526(transcript)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007419"(ventral cord development)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0043974"(histone H3-K27 acetylation)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070615"|go:"GO:0070983"(dendrite guidance)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030088|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P25439|reactome:R-DME-1266695|reactome:R-DME-3214858|reactome:R-DME-3247509|reactome:R-DME-8939243 pubmed:11331758(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ewgcgNM6BnGIGEzX+3AFSniF79s7227 rogid:+pqTXhDIJ2DgEQoHQwnnBdat8kQ7227 intact-crc:8950EFA12F12ADE8|rigid:BLD8rHKMLW7lvpXiDTlvWHAyfqQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P54733 uniprotkb:P25439 intact:EBI-203549|intact:EBI-1628120|uniprotkb:Q24479|uniprotkb:Q95RP5|uniprotkb:Q9V3B3|uniprotkb:Q9V456|ensemblmetazoa:FBpp0080331|ensemblmetazoa:FBpp0080332|ensemblmetazoa:FBpp0080333|ensemblmetazoa:FBpp0080334 intact:EBI-868480|uniprotkb:Q9VUW5|uniprotkb:Q9VUW6|uniprotkb:A4V1Z7|uniprotkb:A4V1Z8|ensemblmetazoa:FBpp0075280|ensemblmetazoa:FBpp0075281 psi-mi:ccne_drome(display_long)|uniprotkb:CycE(gene name)|psi-mi:CycE(display_short)|uniprotkb:CG3938(orf name) psi-mi:brm_drome(display_long)|uniprotkb:Homeotic gene regulator(gene name synonym)|uniprotkb:Protein brahma(gene name synonym)|uniprotkb:brm(gene name)|psi-mi:brm(display_short)|uniprotkb:CG5942(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871698 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476959.1|refseq:NP_476960.1|refseq:NP_723924.1|refseq:NP_723925.1|refseq:NP_723926.1|flybase:FBgn0010382|dip:DIP-18331N|ensemblmetazoa:FBgn0010382(gene)|ensemblmetazoa:FBtr0080773(transcript)|ensemblmetazoa:FBtr0080774(transcript)|ensemblmetazoa:FBtr0080775(transcript)|ensemblmetazoa:FBtr0080776(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007277"(pole cell development)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035736"(cell proliferation involved in compound eye morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048665"(neuron fate specification)|go:"GO:0090210"(regulation of establishment of blood-brain barrier)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P54733|reactome:R-DME-1538133|reactome:R-DME-187577|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-9706019 refseq:NP_730089.1|flybase:FBgn0000212|refseq:NP_730088.1|refseq:NP_536745.4|refseq:NP_536746.1|dip:DIP-36728N|ensemblmetazoa:FBgn0000212(gene)|ensemblmetazoa:FBtr0075525(transcript)|ensemblmetazoa:FBtr0075526(transcript)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007419"(ventral cord development)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0043974"(histone H3-K27 acetylation)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070615"|go:"GO:0070983"(dendrite guidance)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030088|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P25439|reactome:R-DME-1266695|reactome:R-DME-3214858|reactome:R-DME-3247509|reactome:R-DME-8939243 pubmed:12093739(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:AwK/vwBDPgICbmeNxOxrcsj5kiQ7227 rogid:+pqTXhDIJ2DgEQoHQwnnBdat8kQ7227 intact-crc:43D9D9B442239E1A|rigid:PhqITdh//oklP5S4CRQA9hYg+1o false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P22814 uniprotkb:Q24039 intact:EBI-868309|uniprotkb:A0AVT9|uniprotkb:O76551|uniprotkb:Q6SD78|uniprotkb:Q7KPD6|uniprotkb:Q8MRF4|uniprotkb:Q9TVG1|uniprotkb:Q9TVZ7|uniprotkb:Q9TZQ9|uniprotkb:Q9TZR0|uniprotkb:Q9VRB6|intact:EBI-1639673|ensemblmetazoa:FBpp0076971|ensemblmetazoa:FBpp0311837 intact:EBI-148540|uniprotkb:Q9W0B5|ensemblmetazoa:FBpp0072643 psi-mi:runt_drome(display_long)|uniprotkb:run(gene name)|psi-mi:run(display_short)|uniprotkb:CG1849(orf name) psi-mi:bro_drome(display_long)|uniprotkb:Bro(gene name)|psi-mi:Bro(display_short)|uniprotkb:CG7960(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871702 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001285501.1|refseq:NP_523424.2|flybase:FBgn0003300|ensemblmetazoa:FBgn0003300(gene)|ensemblmetazoa:FBtr0077279(transcript)|ensemblmetazoa:FBtr0345922(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007377"(germ-band extension)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007419"(ventral cord development)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048592"(eye morphogenesis)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|reactome:R-DME-549127|reactome:R-DME-8878166|reactome:R-DME-8931987|reactome:R-DME-8934593|reactome:R-DME-8936459|reactome:R-DME-8939236|reactome:R-DME-8939243|reactome:R-DME-8939245|reactome:R-DME-8939246|reactome:R-DME-8939247|reactome:R-DME-8939902|reactome:R-DME-8940973|reactome:R-DME-8941326|reactome:R-DME-9018519 refseq:NP_477066.2|flybase:FBgn0013755|ensemblmetazoa:FBgn0013755(gene)|ensemblmetazoa:FBtr0072760(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0048749"(compound eye development)|interpro:IPR003417(Core binding factor, beta subunit)|interpro:IPR036552 pubmed:9077443(see-also)|pubmed:10393111(see-also)|pubmed:8622696(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:AhHjibxAU093Edu1nQPWbMTKGFo7227 rogid:iwIYzD3QhqLnZ/09bISrhLuC47Y7227 intact-crc:0E3DA061B28AF075|rigid:B6c4iZJzyllzUglRwdQ+USMesI8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9U1K1 uniprotkb:P92208 intact:EBI-91672|intact:EBI-867570|intact:EBI-499570|uniprotkb:Q9VIN3|uniprotkb:Q9VIN4|uniprotkb:Q5U0Z8|uniprotkb:Q8INV3|uniprotkb:Q8INV4|uniprotkb:Q8INV5|uniprotkb:Q8SXP3|uniprotkb:Q8T8P8|uniprotkb:Q9U4F0|uniprotkb:Q9U4F1|ensemblmetazoa:FBpp0080884 intact:EBI-74487|uniprotkb:O01366|uniprotkb:Q94542|ensemblmetazoa:FBpp0079676|ensemblmetazoa:FBpp0290204|ensemblmetazoa:FBpp0291573 psi-mi:spir_drome(display_long)|uniprotkb:spir(gene name)|psi-mi:spir(display_short)|uniprotkb:p150-Spir(gene name synonym)|uniprotkb:CG10076(orf name) psi-mi:jnk_drome(display_long)|uniprotkb:bsk(gene name)|psi-mi:bsk(display_short)|uniprotkb:JNK(gene name synonym)|uniprotkb:CG5680(orf name)|uniprotkb:Protein basket(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871706 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001286100.1|refseq:NP_524854.2|refseq:NP_724254.1|refseq:NP_724255.1|refseq:NP_724256.2|flybase:FBgn0003475|ensemblmetazoa:FBgn0003475(gene)|ensemblmetazoa:FBtr0081352(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046907"(intracellular transport)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0048477"(oogenesis)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0007316"(pole plasm RNA localization)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051639"(actin filament network formation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011019(KIND)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030029"(actin filament-based process)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0030036"(actin cytoskeleton organization)|interpro:IPR029901|rcsb pdb:3MMV|rcsb pdb:3MN5|rcsb pdb:3MN6|rcsb pdb:3MN7|rcsb pdb:3MN9|rcsb pdb:3UE5|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030717"(oocyte karyosome formation)|rcsb pdb:4EFH|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045010"(actin nucleation)|refseq:NP_001246102.1|dip:DIP-17301N go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048666"(neuron development)|go:"GO:0048674"(collateral sprouting of injured axon)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:5AWM|reactome:R-DME-193648|reactome:R-DME-209397|reactome:R-DME-209409|reactome:R-DME-209425|reactome:R-DME-209459|reactome:R-DME-2559580|reactome:R-DME-2871796|reactome:R-DME-376172|reactome:R-DME-450321|reactome:R-DME-450341|reactome:R-DME-9007892|refseq:NP_001162930.1|refseq:NP_001162932.1|refseq:NP_723541.1|flybase:FBgn0000229|dip:DIP-17307N|ensemblmetazoa:FBgn0000229(gene)|ensemblmetazoa:FBtr0080087(transcript)|ensemblmetazoa:FBtr0300982(transcript)|ensemblmetazoa:FBtr0302378(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007616"(long-term memory)|go:"GO:0009408"(response to heat)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016319"(mushroom body development)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035006"(melanization defense response)|go:"GO:0035313"(wound healing, spreading of epidermal cells) pubmed:10744979(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:d5/uax72i+0dvjWvfORgiCSMjwQ7227 rogid:o81/FEGIpdc5K06yBAQusZL6seI7227 intact-crc:7BE85FE3B4365CFD|rigid:4cqazN4BDJP98JH7UeKT8wQ3AF4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O61444 uniprotkb:P92208 intact:EBI-95608|uniprotkb:O61445|ensemblmetazoa:FBpp0081378|ensemblmetazoa:FBpp0289672|ensemblmetazoa:FBpp0306434 intact:EBI-74487|uniprotkb:O01366|uniprotkb:Q94542|ensemblmetazoa:FBpp0079676|ensemblmetazoa:FBpp0290204|ensemblmetazoa:FBpp0291573 psi-mi:o61444_drome(display_long)|uniprotkb:Mkk4(gene name)|psi-mi:Mkk4(display_short)|uniprotkb:P-MKK4(gene name synonym)|uniprotkb:142758_at(gene name synonym)|uniprotkb:CT27508(gene name synonym)|uniprotkb:D-MKK4(gene name synonym)|uniprotkb:DMKK4(gene name synonym)|uniprotkb:Dmel\CG9738(gene name synonym)|uniprotkb:JNKK2(gene name synonym)|uniprotkb:MAPKK4(gene name synonym)|uniprotkb:MKK4(gene name synonym)|uniprotkb:Mpk4(gene name synonym)|uniprotkb:SEK1(gene name synonym)|uniprotkb:dMKK4(gene name synonym)|uniprotkb:dMkk4(gene name synonym)|uniprotkb:mkk4(gene name synonym)|uniprotkb:Dmel_CG9738(orf name)|uniprotkb:CG9738(orf name) psi-mi:jnk_drome(display_long)|uniprotkb:bsk(gene name)|psi-mi:bsk(display_short)|uniprotkb:JNK(gene name synonym)|uniprotkb:CG5680(orf name)|uniprotkb:Protein basket(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871710 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0048082"(regulation of adult chitin-containing cuticle pigmentation)|ensemblmetazoa:FBgn0024326(gene)|ensemblmetazoa:FBtr0081892(transcript)|ensemblmetazoa:FBtr0300443(transcript)|ensemblmetazoa:FBtr0334320(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0048666"(neuron development)|interpro:IPR000719(Protein kinase, core)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0030424"(axon)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-2559580|refseq:NP_001163551.1|refseq:NP_477353.1|flybase:FBgn0024326|refseq:NP_001262375.1|reactome:R-DME-2871796|reactome:R-DME-450321 go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048666"(neuron development)|go:"GO:0048674"(collateral sprouting of injured axon)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:5AWM|reactome:R-DME-193648|reactome:R-DME-209397|reactome:R-DME-209409|reactome:R-DME-209425|reactome:R-DME-209459|reactome:R-DME-2559580|reactome:R-DME-2871796|reactome:R-DME-376172|reactome:R-DME-450321|reactome:R-DME-450341|reactome:R-DME-9007892|refseq:NP_001162930.1|refseq:NP_001162932.1|refseq:NP_723541.1|flybase:FBgn0000229|dip:DIP-17307N|ensemblmetazoa:FBgn0000229(gene)|ensemblmetazoa:FBtr0080087(transcript)|ensemblmetazoa:FBtr0300982(transcript)|ensemblmetazoa:FBtr0302378(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007616"(long-term memory)|go:"GO:0009408"(response to heat)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016319"(mushroom body development)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035006"(melanization defense response)|go:"GO:0035313"(wound healing, spreading of epidermal cells) pubmed:9584193(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:HldoJzQNkDXfKZR74vYg0dyj+CU7227 rogid:o81/FEGIpdc5K06yBAQusZL6seI7227 intact-crc:5FD9A7E715CA75D5|rigid:VcuAMd8oug3H/nNVeFjxil9Z6kw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P21525 uniprotkb:P92208 intact:EBI-195448|uniprotkb:Q400M6|uniprotkb:Q400M7|uniprotkb:Q53YJ8|uniprotkb:A8MPI0|uniprotkb:Q8T9E2|uniprotkb:Q9BH37|uniprotkb:Q9NBW7|uniprotkb:Q9VAH5|ensemblmetazoa:FBpp0288515 intact:EBI-74487|uniprotkb:O01366|uniprotkb:Q94542|ensemblmetazoa:FBpp0079676|ensemblmetazoa:FBpp0290204|ensemblmetazoa:FBpp0291573 psi-mi:fosla_drome(display_long)|uniprotkb:kay(gene name)|psi-mi:kay(display_short)|uniprotkb:Fra(gene name synonym)|uniprotkb:CG15509(orf name)|uniprotkb:Fos-related antigen(gene name synonym)|uniprotkb:AP-1(gene name synonym) psi-mi:jnk_drome(display_long)|uniprotkb:bsk(gene name)|psi-mi:bsk(display_short)|uniprotkb:JNK(gene name synonym)|uniprotkb:CG5680(orf name)|uniprotkb:Protein basket(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871714 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027577.2|refseq:NP_001027578.1|refseq:NP_001027579.1|flybase:FBgn0001297|dip:DIP-22245N|ensemblmetazoa:FBgn0001297(gene)|ensemblmetazoa:FBtr0290076(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006964"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007281"(germ cell development)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0009611"(response to wounding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0035220"(wing disc development)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042060"(wound healing)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048674"(collateral sprouting of injured axon)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|reactome:R-DME-209394|reactome:R-DME-209409|reactome:R-DME-209425|reactome:R-DME-2559580|reactome:R-DME-2871796|reactome:R-DME-450341 go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048666"(neuron development)|go:"GO:0048674"(collateral sprouting of injured axon)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:5AWM|reactome:R-DME-193648|reactome:R-DME-209397|reactome:R-DME-209409|reactome:R-DME-209425|reactome:R-DME-209459|reactome:R-DME-2559580|reactome:R-DME-2871796|reactome:R-DME-376172|reactome:R-DME-450321|reactome:R-DME-450341|reactome:R-DME-9007892|refseq:NP_001162930.1|refseq:NP_001162932.1|refseq:NP_723541.1|flybase:FBgn0000229|dip:DIP-17307N|ensemblmetazoa:FBgn0000229(gene)|ensemblmetazoa:FBtr0080087(transcript)|ensemblmetazoa:FBtr0300982(transcript)|ensemblmetazoa:FBtr0302378(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007616"(long-term memory)|go:"GO:0009408"(response to heat)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016319"(mushroom body development)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035006"(melanization defense response)|go:"GO:0035313"(wound healing, spreading of epidermal cells) pubmed:11865058(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:P1VNgVJTLHiW0Qxi4IeXzf0fWDw7227 rogid:o81/FEGIpdc5K06yBAQusZL6seI7227 intact-crc:1CA9CFB1409F5C41|rigid:6vb5bpRy1KInZM3eK+HGXCNACpI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18289 uniprotkb:P92208 intact:EBI-159948|uniprotkb:Q0E9D8|ensemblmetazoa:FBpp0087498|ensemblmetazoa:FBpp0087499|uniprotkb:Q9V5G4 intact:EBI-74487|uniprotkb:O01366|uniprotkb:Q94542|ensemblmetazoa:FBpp0079676|ensemblmetazoa:FBpp0290204|ensemblmetazoa:FBpp0291573 psi-mi:jra_drome(display_long)|uniprotkb:Jra(gene name)|psi-mi:Jra(display_short)|uniprotkb:jun(gene name synonym)|uniprotkb:CG2275(orf name)|uniprotkb:Jun-related antigen(gene name synonym)|uniprotkb:dJRA(gene name synonym)|uniprotkb:dJun(gene name synonym) psi-mi:jnk_drome(display_long)|uniprotkb:bsk(gene name)|psi-mi:bsk(display_short)|uniprotkb:JNK(gene name synonym)|uniprotkb:CG5680(orf name)|uniprotkb:Protein basket(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871718 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476586.1|refseq:NP_724882.1|flybase:FBgn0001291|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029823|reactome:R-DME-209394|reactome:R-DME-2559580|reactome:R-DME-209409|reactome:R-DME-2871796|reactome:R-DME-450341|reactome:R-DME-209425|ensemblmetazoa:FBgn0001291(gene)|ensemblmetazoa:FBtr0088410(transcript)|ensemblmetazoa:FBtr0088411(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007254"(JNK cascade)|go:"GO:0007391"(dorsal closure)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0008348"(negative regulation of antimicrobial humoral response)|go:"GO:0010259"(multicellular organism aging)|dip:DIP-18982N go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048666"(neuron development)|go:"GO:0048674"(collateral sprouting of injured axon)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:5AWM|reactome:R-DME-193648|reactome:R-DME-209397|reactome:R-DME-209409|reactome:R-DME-209425|reactome:R-DME-209459|reactome:R-DME-2559580|reactome:R-DME-2871796|reactome:R-DME-376172|reactome:R-DME-450321|reactome:R-DME-450341|reactome:R-DME-9007892|refseq:NP_001162930.1|refseq:NP_001162932.1|refseq:NP_723541.1|flybase:FBgn0000229|dip:DIP-17307N|ensemblmetazoa:FBgn0000229(gene)|ensemblmetazoa:FBtr0080087(transcript)|ensemblmetazoa:FBtr0300982(transcript)|ensemblmetazoa:FBtr0302378(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007616"(long-term memory)|go:"GO:0009408"(response to heat)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016319"(mushroom body development)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035006"(melanization defense response)|go:"GO:0035313"(wound healing, spreading of epidermal cells) pubmed:11865058(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:2mZFIBFRb3iqZpVcG9UScYWj/I47227 rogid:o81/FEGIpdc5K06yBAQusZL6seI7227 intact-crc:FB509F2AD3B8F293|rigid:tKTmTsBooen1SYNwHVYdvJoLAHU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P00528 uniprotkb:P08630 intact:EBI-87092|uniprotkb:A4V1H7|uniprotkb:O18372|uniprotkb:Q9VZA2|ensemblmetazoa:FBpp0073177|ensemblmetazoa:FBpp0099944|ensemblmetazoa:FBpp0099946|ensemblmetazoa:FBpp0099947|ensemblmetazoa:FBpp0099948|ensemblmetazoa:FBpp0291750|ensemblmetazoa:FBpp0293526|ensemblmetazoa:FBpp0293527 intact:EBI-274134|uniprotkb:A4V0F3|uniprotkb:A4V0F4|uniprotkb:Q6NNV0|uniprotkb:O45032|uniprotkb:O76132|uniprotkb:O76133|uniprotkb:P11361|uniprotkb:Q8T0A0|uniprotkb:Q9VLQ2|uniprotkb:Q9VLQ3|ensemblmetazoa:FBpp0079236|ensemblmetazoa:FBpp0079237|ensemblmetazoa:FBpp0111749 psi-mi:src64_drome(display_long)|uniprotkb:Src64B(gene name)|psi-mi:Src64B(display_short)|uniprotkb:Src1(gene name synonym)|uniprotkb:CG7524(orf name) psi-mi:btkl_drome(display_long)|uniprotkb:Btk29A(gene name)|psi-mi:Btk29A(display_short)|uniprotkb:Src2(gene name synonym)|uniprotkb:Src29A(gene name synonym)|uniprotkb:Tec29(gene name synonym)|uniprotkb:CG8049(orf name)|uniprotkb:Dsrc28C(gene name synonym)|uniprotkb:Dsrc29a(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871722 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-DME-1251985|reactome:R-DME-1253288|reactome:R-DME-1257604|reactome:R-DME-1295596|reactome:R-DME-1433557|reactome:R-DME-177929|reactome:R-DME-180292|reactome:R-DME-186763|reactome:R-DME-2454202|reactome:R-DME-354192|reactome:R-DME-373753|reactome:R-DME-1227986|reactome:R-DME-375165|reactome:R-DME-3928662|reactome:R-DME-3928663|reactome:R-DME-3928664|reactome:R-DME-3928665|reactome:R-DME-399954|reactome:R-DME-399955|reactome:R-DME-399956|reactome:R-DME-418592|reactome:R-DME-418594|reactome:R-DME-430116|reactome:R-DME-432142|reactome:R-DME-4420097|reactome:R-DME-456926|reactome:R-DME-5621575|reactome:R-DME-5663220|reactome:R-DME-5673000|reactome:R-DME-5673001|reactome:R-DME-5674135|reactome:R-DME-6798695|reactome:R-DME-6811558|reactome:R-DME-69231|reactome:R-DME-8934903|reactome:R-DME-8941858|reactome:R-DME-9009391|reactome:R-DME-9013407|reactome:R-DME-9027276|reactome:R-DME-9027284|reactome:R-DME-418885|reactome:R-DME-912631|ensemblmetazoa:FBgn0262733(gene)|ensemblmetazoa:FBtr0073321(transcript)|ensemblmetazoa:FBtr0100504(transcript)|ensemblmetazoa:FBtr0100505(transcript)|ensemblmetazoa:FBtr0100507(transcript)|ensemblmetazoa:FBtr0100508(transcript)|ensemblmetazoa:FBtr0302594(transcript)|ensemblmetazoa:FBtr0304989(transcript)|ensemblmetazoa:FBtr0304990(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0007349"(cellularization)|go:"GO:0007411"(axon guidance)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007616"(long-term memory)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008302"(female germline ring canal formation, actin assembly)|go:"GO:0008335"(female germline ring canal stabilization)|go:"GO:0016319"(mushroom body development)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030046"(parallel actin filament bundle assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030723"(ovarian fusome organization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0034332"(adherens junction organization)|go:"GO:0036058"(filtration diaphragm assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0045172"(germline ring canal)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045874"(positive regulation of sevenless signaling pathway)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048477"(oogenesis)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0120176"(positive regulation of torso signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|go:"GO:0030717"(oocyte karyosome formation)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|refseq:NP_001014561.1|refseq:NP_001014562.1|refseq:NP_001014563.1|refseq:NP_001014564.1|refseq:NP_001189051.1|refseq:NP_524934.2|flybase:FBgn0262733|refseq:NP_001246628.1|refseq:NP_001246629.1|dip:DIP-17438N refseq:NP_001097120.1|refseq:NP_001097121.1|refseq:NP_476745.1|refseq:NP_476746.1|refseq:NP_723369.1|refseq:NP_723370.1|flybase:FBgn0003502|dip:DIP-23748N|ensemblmetazoa:FBgn0003502(gene)|ensemblmetazoa:FBtr0079616(transcript)|ensemblmetazoa:FBtr0079617(transcript)|ensemblmetazoa:FBtr0112836(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007254"(JNK cascade)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0007349"(cellularization)|go:"GO:0007391"(dorsal closure)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007485"(imaginal disc-derived male genitalia development)|go:"GO:0007619"(courtship behavior)|go:"GO:0008258"(head involution)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0030723"(ovarian fusome organization)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0045172"(germline ring canal)|go:"GO:0045177"(apical part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0046960"(sensitization)|go:"GO:0048477"(oogenesis)|go:"GO:0071944"(cell periphery)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR001562(Tec/Btk)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|reactome:R-DME-111465|reactome:R-DME-2871809|reactome:R-DME-512988 pubmed:9660966(see-also)|pubmed:9660965(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:o3ytx+aAkV5m40RrH4wV+CJapqs7227 rogid:UyUdNmuGZavbheoHV1AQyovlUMU7227 intact-crc:7D1884DACBF9BB77|rigid:O/OYJuEv+mRuA4EhMvALqgHIiU0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O44783 uniprotkb:Q09147 intact:EBI-132097|uniprotkb:A4V1F3|uniprotkb:Q6AWR4|uniprotkb:Q9VZP7|ensemblmetazoa:FBpp0073004|ensemblmetazoa:FBpp0073005 intact:EBI-122593|uniprotkb:A4V1Y3|uniprotkb:Q712V2|uniprotkb:Q9VUC8|ensemblmetazoa:FBpp0075520|ensemblmetazoa:FBpp0100143 psi-mi:spy_drome(display_long)|uniprotkb:sty(gene name)|psi-mi:sty(display_short)|uniprotkb:CG1921(orf name) psi-mi:fgfr2_drome(display_long)|uniprotkb:FR2(gene name synonym)|uniprotkb:HD-311(gene name synonym)|uniprotkb:Protein breathless(gene name synonym)|uniprotkb:Tk2(gene name synonym)|uniprotkb:Tyrosine kinase 2(gene name synonym)|uniprotkb:Tyrosine kinase receptor HD-311(gene name synonym)|uniprotkb:CG32134(orf name)|uniprotkb:btl(gene name)|psi-mi:btl(display_short)|uniprotkb:dFGF-R1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871726 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523902.2|refseq:NP_728881.1|flybase:FBgn0014388|ensemblmetazoa:FBgn0014388(gene)|ensemblmetazoa:FBtr0073145(transcript)|ensemblmetazoa:FBtr0073146(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0021782"(glial cell development)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045314"(regulation of compound eye photoreceptor development)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0055001"(muscle cell development)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0110109"(negative regulation of imaginal disc-derived wing vein specification)|interpro:IPR007875(Sprouty)|reactome:R-DME-1295596|reactome:R-DME-182971|go:"GO:0120177"(negative regulation of torso signaling pathway)|dip:DIP-17914N refseq:NP_001014583.1|refseq:NP_729956.1|ensemblmetazoa:FBgn0285896(gene)|ensemblmetazoa:FBtr0075778(transcript)|ensemblmetazoa:FBtr0100676(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005007"(fibroblast growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007428"(primary branching, open tracheal system)|go:"GO:0007429"(secondary branching, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035008"(positive regulation of melanization defense response)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035154"(terminal cell fate specification, open tracheal system)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035215"(genital disc development)|go:"GO:0035230"(cytoneme)|go:"GO:0042690"(negative regulation of crystal cell differentiation)|go:"GO:0043235"(receptor complex)|go:"GO:0045614"(negative regulation of plasmatocyte differentiation)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0060438"(trachea development)|reactome:R-DME-5654719|reactome:R-DME-5654720|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5654733|reactome:R-DME-5673001|reactome:R-DME-6811558|go:"GO:0060446"(branching involved in open tracheal system development)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR000719(Protein kinase, core)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036179|reactome:R-DME-109704|reactome:R-DME-1257604|reactome:R-DME-1307965|reactome:R-DME-190322|reactome:R-DME-190370|reactome:R-DME-190371|reactome:R-DME-190372|reactome:R-DME-190373|reactome:R-DME-190374|reactome:R-DME-190375|reactome:R-DME-190377|reactome:R-DME-5654219|reactome:R-DME-5654221|reactome:R-DME-5654227|reactome:R-DME-5654228|reactome:R-DME-5654687|reactome:R-DME-5654688|reactome:R-DME-5654689|reactome:R-DME-5654693|reactome:R-DME-5654695|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654710|reactome:R-DME-5654712|flybase:FBgn0285896 pubmed:10457022(see-also)|pubmed:10226010(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Epk95p/MSvHN+VVqzKqaTdmoO6g7227 rogid:8Gq7DGFh9sr1Aa+42t2KqlK+a687227 intact-crc:4818357D8FD9BD31|rigid:+OlzJoYzI5cAKLaeXsgPgtITN9I false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10090 uniprotkb:P12428 intact:EBI-93778|uniprotkb:Q9V3A2|uniprotkb:Q9XY33|ensemblmetazoa:FBpp0070468 intact:EBI-122973|uniprotkb:Q24264|uniprotkb:Q7KVI1|uniprotkb:Q7KVI2|uniprotkb:Q8MRN9|uniprotkb:Q9W1N7|ensemblmetazoa:FBpp0072026|ensemblmetazoa:FBpp0312192 psi-mi:white_drome(display_long)|uniprotkb:w(gene name)|psi-mi:w(display_short)|uniprotkb:CG2759(orf name) psi-mi:brown_drome(display_long)|uniprotkb:CG17632(orf name)|uniprotkb:bw(gene name)|psi-mi:bw(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871730 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476787.1|flybase:FBgn0003996|ensemblmetazoa:FBgn0003996(gene)|ensemblmetazoa:FBtr0070490(transcript)|go:"GO:0005275"(amine transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006727"(ommochrome biosynthetic process)|go:"GO:0006856"(eye pigment precursor transport)|go:"GO:0007613"(memory)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008558"(ABC-type guanine transporter activity)|go:"GO:0015196"(L-tryptophan transmembrane transporter activity)|go:"GO:0015842"(aminergic neurotransmitter loading into synaptic vesicle)|go:"GO:0031409"(pigment binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042332"(gravitaxis)|go:"GO:0042401"(cellular biogenic amine biosynthetic process)|go:"GO:0042441"(eye pigment metabolic process)|go:"GO:0048072"(compound eye pigmentation)|go:"GO:0048770"(pigment granule)|go:"GO:0051615"(histamine uptake)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070731"(cGMP transport)|go:"GO:0090740"(integral component of pigment granule membrane)|go:"GO:0098793"(presynapse)|go:"GO:1905948"(ABC-type 3',5'-cyclic GMP transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005284(Pigment precursor permease)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR043926|dip:DIP-388N flybase:FBgn0000241|ensemblmetazoa:FBgn0000241(gene)|ensemblmetazoa:FBtr0072117(transcript)|ensemblmetazoa:FBtr0346612(transcript)|go:"GO:0005275"(amine transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006727"(ommochrome biosynthetic process)|go:"GO:0006856"(eye pigment precursor transport)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015842"(aminergic neurotransmitter loading into synaptic vesicle)|go:"GO:0031409"(pigment binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098793"(presynapse)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005284(Pigment precursor permease)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR043926|reactome:R-DME-1369062|reactome:R-DME-189451|reactome:R-DME-189483|reactome:R-DME-917937|go:"GO:0016021"(integral component of membrane)|refseq:NP_001286769.1|refseq:NP_523824.1|dip:DIP-387N pubmed:3149712(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:nE6hAxiYy5nq99VxDZoDohuWpqc7227 rogid:6q/lPRovgGsdqIQq4alZJQZzUw47227 intact-crc:228CD0FAFA011477|rigid:LX72k4OqPU2XmjxpaFXjEHw/uZ8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9XYM0 uniprotkb:O77086 intact:EBI-99477|uniprotkb:Q53XD2|ensemblmetazoa:FBpp0088181|ensemblmetazoa:FBpp0088182 intact:EBI-868530|uniprotkb:Q9W3W3|uniprotkb:Q1ECB6|uniprotkb:Q7YU30|uniprotkb:Q86B63|ensemblmetazoa:FBpp0289753 psi-mi:crk_drome(display_long)|uniprotkb:Crk(gene name)|psi-mi:Crk(display_short)|uniprotkb:CG1587(orf name) psi-mi:c3g_drome(display_long)|uniprotkb:CRK SH3-binding GNRP(gene name synonym)|uniprotkb:C3G(gene name)|psi-mi:C3G(display_short)|uniprotkb:CG42328(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871734 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651908.1|refseq:NP_726549.1|flybase:FBgn0024811|ensemblmetazoa:FBgn0024811(gene)|ensemblmetazoa:FBtr0089112(transcript)|ensemblmetazoa:FBtr0089113(transcript)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:Q9XYM0|reactome:R-DME-186763|reactome:R-DME-8849471|reactome:R-DME-9027284|reactome:R-DME-912631|dip:DIP-21287N refseq:NP_572350.2|refseq:NP_788867.1|flybase:FBgn0259228|ensemblmetazoa:FBgn0259228(gene)|ensemblmetazoa:FBtr0300526(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007525"(somatic muscle development)|go:"GO:0016203"(muscle attachment)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR019804|interpro:IPR023578|interpro:IPR036964|reactome:R-DME-186763|reactome:R-DME-9027284|reactome:R-DME-912631 pubmed:9878058(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:/aQyKHKPKNANVUGCJwbvoeZrYiI7227 rogid:Doje9BtKYjuGRenCSrSGfXBV+k47227 intact-crc:F44D10B974ECED55|rigid:lIJN1txtWj0v7qTgiy3FL7VUw5A false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P15330 uniprotkb:Q03017 intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222 intact:EBI-200600|uniprotkb:A4V0S3|uniprotkb:Q0E8Q3|uniprotkb:Q9V3M6|ensemblmetazoa:FBpp0080402|ensemblmetazoa:FBpp0080403|ensemblmetazoa:FBpp0089296|ensemblmetazoa:FBpp0308004 psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name) psi-mi:cact_drome(display_long)|uniprotkb:CG5848(orf name)|uniprotkb:cact(gene name)|psi-mi:cact(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871738 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542 refseq:NP_476942.1|refseq:NP_476943.1|refseq:NP_723960.1|refseq:NP_995721.1|flybase:FBgn0000250|refseq:NP_001260496.1|dip:DIP-17846N|ensemblmetazoa:FBgn0000250(gene)|ensemblmetazoa:FBtr0080844(transcript)|ensemblmetazoa:FBtr0080845(transcript)|ensemblmetazoa:FBtr0080847(transcript)|ensemblmetazoa:FBtr0337081(transcript)|go:"GO:0002789"(negative regulation of antifungal peptide production)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007399"(nervous system development)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0071212"(subsynaptic reticulum)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-1169091|reactome:R-DME-202424|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-445989|reactome:R-DME-5607764|reactome:R-DME-9020702 pubmed:8202491(see-also)|pubmed:9510254(see-also)|pubmed:10660560(see-also)|pubmed:8072548(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227 rogid:xVqWiRJtkb1WDO5GmztYwgdB9iI7227 intact-crc:ABB2FBA302634787|rigid:YUloJ2l9wJFVD7cm3QpZPOdkSDc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P98149 uniprotkb:Q03017 intact:EBI-188843|uniprotkb:Q1LYZ5|uniprotkb:Q8MT54|uniprotkb:Q9VJE2|ensemblmetazoa:FBpp0080561|ensemblmetazoa:FBpp0080562|ensemblmetazoa:FBpp0290793 intact:EBI-200600|uniprotkb:A4V0S3|uniprotkb:Q0E8Q3|uniprotkb:Q9V3M6|ensemblmetazoa:FBpp0080402|ensemblmetazoa:FBpp0080403|ensemblmetazoa:FBpp0089296|ensemblmetazoa:FBpp0308004 psi-mi:dif_drome(display_long)|uniprotkb:Dif(gene name)|psi-mi:Dif(display_short)|uniprotkb:CG6794(orf name) psi-mi:cact_drome(display_long)|uniprotkb:CG5848(orf name)|uniprotkb:cact(gene name)|psi-mi:cact(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871742 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162999.1|refseq:NP_523589.2|refseq:NP_724050.1|flybase:FBgn0011274|dip:DIP-34965N|ensemblmetazoa:FBgn0011274(gene)|ensemblmetazoa:FBtr0081008(transcript)|ensemblmetazoa:FBtr0081009(transcript)|ensemblmetazoa:FBtr0301578(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0034097"(response to cytokine)|go:"GO:0035070"(salivary gland histolysis)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011363(Dorsal protein)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-9020702|reactome:R-DME-933542 refseq:NP_476942.1|refseq:NP_476943.1|refseq:NP_723960.1|refseq:NP_995721.1|flybase:FBgn0000250|refseq:NP_001260496.1|dip:DIP-17846N|ensemblmetazoa:FBgn0000250(gene)|ensemblmetazoa:FBtr0080844(transcript)|ensemblmetazoa:FBtr0080845(transcript)|ensemblmetazoa:FBtr0080847(transcript)|ensemblmetazoa:FBtr0337081(transcript)|go:"GO:0002789"(negative regulation of antifungal peptide production)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007399"(nervous system development)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0071212"(subsynaptic reticulum)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-1169091|reactome:R-DME-202424|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-445989|reactome:R-DME-5607764|reactome:R-DME-9020702 pubmed:9510254(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:LlE+/iR1xdrGI7Qg/QJiRJHNmL87227 rogid:xVqWiRJtkb1WDO5GmztYwgdB9iI7227 intact-crc:8FC0215CC7523250|rigid:GMruWr3EGdy/u3dHOFp+kgrF4rU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08181 uniprotkb:Q03017 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 intact:EBI-200600|uniprotkb:A4V0S3|uniprotkb:Q0E8Q3|uniprotkb:Q9V3M6|ensemblmetazoa:FBpp0080402|ensemblmetazoa:FBpp0080403|ensemblmetazoa:FBpp0089296|ensemblmetazoa:FBpp0308004 psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:cact_drome(display_long)|uniprotkb:CG5848(orf name)|uniprotkb:cact(gene name)|psi-mi:cact(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871746 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N refseq:NP_476942.1|refseq:NP_476943.1|refseq:NP_723960.1|refseq:NP_995721.1|flybase:FBgn0000250|refseq:NP_001260496.1|dip:DIP-17846N|ensemblmetazoa:FBgn0000250(gene)|ensemblmetazoa:FBtr0080844(transcript)|ensemblmetazoa:FBtr0080845(transcript)|ensemblmetazoa:FBtr0080847(transcript)|ensemblmetazoa:FBtr0337081(transcript)|go:"GO:0002789"(negative regulation of antifungal peptide production)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007399"(nervous system development)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0071212"(subsynaptic reticulum)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-1169091|reactome:R-DME-202424|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-445989|reactome:R-DME-5607764|reactome:R-DME-9020702 pubmed:9407033(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 rogid:xVqWiRJtkb1WDO5GmztYwgdB9iI7227 intact-crc:648A8F9DCF03F4ED|rigid:2Q6kGBicvyme+dmKFRCPcEf6R2k false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8MRC3 uniprotkb:Q03017 intact:EBI-868552|ensemblmetazoa:FBpp0309346 intact:EBI-200600|uniprotkb:A4V0S3|uniprotkb:Q0E8Q3|uniprotkb:Q9V3M6|ensemblmetazoa:FBpp0080402|ensemblmetazoa:FBpp0080403|ensemblmetazoa:FBpp0089296|ensemblmetazoa:FBpp0308004 psi-mi:q8mrc3_drome(display_long)|uniprotkb:cactin(gene name)|psi-mi:cactin(display_short)|uniprotkb:CG1676(orf name) psi-mi:cact_drome(display_long)|uniprotkb:CG5848(orf name)|uniprotkb:cact(gene name)|psi-mi:cact(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871750 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0031114|ensemblmetazoa:FBgn0031114(gene)|ensemblmetazoa:FBtr0340400(transcript)|interpro:IPR018816|interpro:IPR019134 refseq:NP_476942.1|refseq:NP_476943.1|refseq:NP_723960.1|refseq:NP_995721.1|flybase:FBgn0000250|refseq:NP_001260496.1|dip:DIP-17846N|ensemblmetazoa:FBgn0000250(gene)|ensemblmetazoa:FBtr0080844(transcript)|ensemblmetazoa:FBtr0080845(transcript)|ensemblmetazoa:FBtr0080847(transcript)|ensemblmetazoa:FBtr0337081(transcript)|go:"GO:0002789"(negative regulation of antifungal peptide production)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007399"(nervous system development)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0071212"(subsynaptic reticulum)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-1169091|reactome:R-DME-202424|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-445989|reactome:R-DME-5607764|reactome:R-DME-9020702 pubmed:10842059(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:940O7pBIpl90EuWibh5cy9WDy2U7227 rogid:xVqWiRJtkb1WDO5GmztYwgdB9iI7227 intact-crc:2BC96BE38A416754|rigid:c2iCr7BnGihOobJSIKAGtOnr+wE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O96959 uniprotkb:P62152 intact:EBI-868558 intact:EBI-182924|uniprotkb:P07181|uniprotkb:Q9V3T4|ensemblmetazoa:FBpp0087109|ensemblmetazoa:FBpp0087110|ensemblmetazoa:FBpp0293502|ensemblmetazoa:FBpp0293503|ensemblmetazoa:FBpp0311269 psi-mi:o96959_drome(display_long)|uniprotkb:unc-13(gene name)|psi-mi:unc-13(display_short)|uniprotkb:UNC-13(gene name synonym)|uniprotkb:CG2999(orf name) psi-mi:calm_drome(display_long)|uniprotkb:Cam(gene name)|psi-mi:Cam(display_short)|uniprotkb:CG8472(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871754 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0025726|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0061789"(dense core granule priming)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|interpro:IPR027080|interpro:IPR035892|interpro:IPR037302 refseq:NP_523710.1|refseq:NP_725120.1|flybase:FBgn0000253|refseq:NP_001286337.1|refseq:NP_001246276.1|refseq:NP_001246277.1|dip:DIP-42091N|ensemblmetazoa:FBgn0000253(gene)|ensemblmetazoa:FBtr0088001(transcript)|ensemblmetazoa:FBtr0088002(transcript)|ensemblmetazoa:FBtr0304963(transcript)|ensemblmetazoa:FBtr0304964(transcript)|ensemblmetazoa:FBtr0345018(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0016028"(rhabdomere)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0016060"(metarhodopsin inactivation)|go:"GO:0016061"(regulation of light-activated channel activity)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030496"(midbody)|go:"GO:0031475"(myosin V complex)|go:"GO:0031476"(myosin VI complex)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031489"(myosin V binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0042052"(rhabdomere development)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070855"(myosin VI head/neck binding)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR039030|rcsb pdb:1MXE|rcsb pdb:2BBM|rcsb pdb:2BBN|rcsb pdb:2BKH|rcsb pdb:2VAS|rcsb pdb:2X51|rcsb pdb:3GN4|rcsb pdb:3L9I|rcsb pdb:4ANJ|rcsb pdb:4CLN|rcsb pdb:4DBP|rcsb pdb:4DBQ|rcsb pdb:4PJJ|reactome:R-DME-111932|reactome:R-DME-111933|reactome:R-DME-111957|reactome:R-DME-114608|reactome:R-DME-1474151|reactome:R-DME-163615|reactome:R-DME-1855204|reactome:R-DME-2025928|reactome:R-DME-203615|reactome:R-DME-2514859|reactome:R-DME-2871809|reactome:R-DME-4086398|reactome:R-DME-438066|reactome:R-DME-442729|reactome:R-DME-451308|reactome:R-DME-5218920|reactome:R-DME-5578775|reactome:R-DME-5607763|reactome:R-DME-5673000|reactome:R-DME-6798695|reactome:R-DME-70221|reactome:R-DME-8876725|reactome:R-DME-9009391|reactome:R-DME-936837|reactome:R-DME-9619229|reactome:R-DME-9648002 pubmed:9813038(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:XPDCP8FbnNcMueksmt6nP0X81vU7227 rogid:YAM6OWzAUWCYzXsvimrlj1fbLl07227 intact-crc:B3F04B030A328942|rigid:AFRNtuVYSh1pSkC83VcrBE5rMV0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P48994 uniprotkb:P62152 intact:EBI-98143|uniprotkb:Q0E9E3|uniprotkb:Q8IH62|uniprotkb:Q8MKU9|uniprotkb:Q9V5B2|intact:EBI-3407987|uniprotkb:C6TPC1|ensemblmetazoa:FBpp0087555|ensemblmetazoa:FBpp0087557|ensemblmetazoa:FBpp0290876 intact:EBI-182924|uniprotkb:P07181|uniprotkb:Q9V3T4|ensemblmetazoa:FBpp0087109|ensemblmetazoa:FBpp0087110|ensemblmetazoa:FBpp0293502|ensemblmetazoa:FBpp0293503|ensemblmetazoa:FBpp0311269 psi-mi:trpl_drome(display_long)|uniprotkb:trpl(gene name)|psi-mi:trpl(display_short)|uniprotkb:CG18345(orf name) psi-mi:calm_drome(display_long)|uniprotkb:Cam(gene name)|psi-mi:Cam(display_short)|uniprotkb:CG8472(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871758 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476895.1|refseq:NP_724822.1|refseq:NP_724823.2|flybase:FBgn0005614|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071454"(cellular response to anoxia)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-114508|reactome:R-DME-139853|reactome:R-DME-3295583|reactome:R-DME-5578775|reactome:R-DME-983695|ensemblmetazoa:FBgn0005614(gene)|ensemblmetazoa:FBtr0088471(transcript)|ensemblmetazoa:FBtr0088473(transcript)|ensemblmetazoa:FBtr0301662(transcript)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006828"(manganese ion transport)|go:"GO:0007589"(body fluid secretion)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010461"(light-activated ion channel activity)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0034703"(cation channel complex)|go:"GO:0035997"(rhabdomere microvillus membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070588"(calcium ion transmembrane transport) refseq:NP_523710.1|refseq:NP_725120.1|flybase:FBgn0000253|refseq:NP_001286337.1|refseq:NP_001246276.1|refseq:NP_001246277.1|dip:DIP-42091N|ensemblmetazoa:FBgn0000253(gene)|ensemblmetazoa:FBtr0088001(transcript)|ensemblmetazoa:FBtr0088002(transcript)|ensemblmetazoa:FBtr0304963(transcript)|ensemblmetazoa:FBtr0304964(transcript)|ensemblmetazoa:FBtr0345018(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0016028"(rhabdomere)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0016060"(metarhodopsin inactivation)|go:"GO:0016061"(regulation of light-activated channel activity)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030496"(midbody)|go:"GO:0031475"(myosin V complex)|go:"GO:0031476"(myosin VI complex)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031489"(myosin V binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0042052"(rhabdomere development)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070855"(myosin VI head/neck binding)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR039030|rcsb pdb:1MXE|rcsb pdb:2BBM|rcsb pdb:2BBN|rcsb pdb:2BKH|rcsb pdb:2VAS|rcsb pdb:2X51|rcsb pdb:3GN4|rcsb pdb:3L9I|rcsb pdb:4ANJ|rcsb pdb:4CLN|rcsb pdb:4DBP|rcsb pdb:4DBQ|rcsb pdb:4PJJ|reactome:R-DME-111932|reactome:R-DME-111933|reactome:R-DME-111957|reactome:R-DME-114608|reactome:R-DME-1474151|reactome:R-DME-163615|reactome:R-DME-1855204|reactome:R-DME-2025928|reactome:R-DME-203615|reactome:R-DME-2514859|reactome:R-DME-2871809|reactome:R-DME-4086398|reactome:R-DME-438066|reactome:R-DME-442729|reactome:R-DME-451308|reactome:R-DME-5218920|reactome:R-DME-5578775|reactome:R-DME-5607763|reactome:R-DME-5673000|reactome:R-DME-6798695|reactome:R-DME-70221|reactome:R-DME-8876725|reactome:R-DME-9009391|reactome:R-DME-936837|reactome:R-DME-9619229|reactome:R-DME-9648002 pubmed:8670063(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:glMABf53+ZJj3aUROdZNs7ts6Bc7227 rogid:YAM6OWzAUWCYzXsvimrlj1fbLl07227 intact-crc:1CA4E42AC50A0FB7|rigid:TpZ1FhOteFJcT6EGRxkxt55xd1I false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VLT5 uniprotkb:P62152 intact:EBI-175222|uniprotkb:O96958|uniprotkb:Q8MS98|uniprotkb:Q9XYD1|uniprotkb:Q9XYD2|ensemblmetazoa:FBpp0079167|ensemblmetazoa:FBpp0305301 intact:EBI-182924|uniprotkb:P07181|uniprotkb:Q9V3T4|ensemblmetazoa:FBpp0087109|ensemblmetazoa:FBpp0087110|ensemblmetazoa:FBpp0293502|ensemblmetazoa:FBpp0293503|ensemblmetazoa:FBpp0311269 psi-mi:poe_drome(display_long)|uniprotkb:poe(gene name)|psi-mi:poe(display_short)|uniprotkb:calo(gene name synonym)|uniprotkb:Protein pushover(gene name synonym)|uniprotkb:Protein Calossin(gene name synonym)|uniprotkb:Interaction calmodulin and colossal molecular mass protein(gene name synonym)|uniprotkb:push(gene name synonym)|uniprotkb:CG14472(orf name) psi-mi:calm_drome(display_long)|uniprotkb:Cam(gene name)|psi-mi:Cam(display_short)|uniprotkb:CG8472(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871762 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476986.1|flybase:FBgn0011230|refseq:NP_001260222.1|ensemblmetazoa:FBgn0011230(gene)|ensemblmetazoa:FBtr0079545(transcript)|ensemblmetazoa:FBtr0333088(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042065"(glial cell growth)|go:"GO:0042066"(perineurial glial growth)|go:"GO:0043186"(P granule)|go:"GO:0050896"(response to stimulus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR025704|interpro:IPR036322|reactome:R-DME-6798695|reactome:R-DME-983168 refseq:NP_523710.1|refseq:NP_725120.1|flybase:FBgn0000253|refseq:NP_001286337.1|refseq:NP_001246276.1|refseq:NP_001246277.1|dip:DIP-42091N|ensemblmetazoa:FBgn0000253(gene)|ensemblmetazoa:FBtr0088001(transcript)|ensemblmetazoa:FBtr0088002(transcript)|ensemblmetazoa:FBtr0304963(transcript)|ensemblmetazoa:FBtr0304964(transcript)|ensemblmetazoa:FBtr0345018(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0016028"(rhabdomere)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0016060"(metarhodopsin inactivation)|go:"GO:0016061"(regulation of light-activated channel activity)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030496"(midbody)|go:"GO:0031475"(myosin V complex)|go:"GO:0031476"(myosin VI complex)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031489"(myosin V binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0042052"(rhabdomere development)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070855"(myosin VI head/neck binding)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR039030|rcsb pdb:1MXE|rcsb pdb:2BBM|rcsb pdb:2BBN|rcsb pdb:2BKH|rcsb pdb:2VAS|rcsb pdb:2X51|rcsb pdb:3GN4|rcsb pdb:3L9I|rcsb pdb:4ANJ|rcsb pdb:4CLN|rcsb pdb:4DBP|rcsb pdb:4DBQ|rcsb pdb:4PJJ|reactome:R-DME-111932|reactome:R-DME-111933|reactome:R-DME-111957|reactome:R-DME-114608|reactome:R-DME-1474151|reactome:R-DME-163615|reactome:R-DME-1855204|reactome:R-DME-2025928|reactome:R-DME-203615|reactome:R-DME-2514859|reactome:R-DME-2871809|reactome:R-DME-4086398|reactome:R-DME-438066|reactome:R-DME-442729|reactome:R-DME-451308|reactome:R-DME-5218920|reactome:R-DME-5578775|reactome:R-DME-5607763|reactome:R-DME-5673000|reactome:R-DME-6798695|reactome:R-DME-70221|reactome:R-DME-8876725|reactome:R-DME-9009391|reactome:R-DME-936837|reactome:R-DME-9619229|reactome:R-DME-9648002 pubmed:9813038(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Asph+mxqqokM0a/B2DKhTtUQ8KQ7227 rogid:YAM6OWzAUWCYzXsvimrlj1fbLl07227 intact-crc:DE47C5C7DF83D437|rigid:F0G/ciW/tV8muUJhUBr0cnt1Q0s false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24193 uniprotkb:P62152 intact:EBI-868587 intact:EBI-182924|uniprotkb:P07181|uniprotkb:Q9V3T4|ensemblmetazoa:FBpp0087109|ensemblmetazoa:FBpp0087110|ensemblmetazoa:FBpp0293502|ensemblmetazoa:FBpp0293503|ensemblmetazoa:FBpp0311269 psi-mi:q24193_drome(display_long)|uniprotkb:plx(gene name)|psi-mi:plx(display_short)|uniprotkb:CG42612(orf name) psi-mi:calm_drome(display_long)|uniprotkb:Cam(gene name)|psi-mi:Cam(display_short)|uniprotkb:CG8472(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871766 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261261|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009986"(cell surface)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR021785|interpro:IPR035969 refseq:NP_523710.1|refseq:NP_725120.1|flybase:FBgn0000253|refseq:NP_001286337.1|refseq:NP_001246276.1|refseq:NP_001246277.1|dip:DIP-42091N|ensemblmetazoa:FBgn0000253(gene)|ensemblmetazoa:FBtr0088001(transcript)|ensemblmetazoa:FBtr0088002(transcript)|ensemblmetazoa:FBtr0304963(transcript)|ensemblmetazoa:FBtr0304964(transcript)|ensemblmetazoa:FBtr0345018(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0016028"(rhabdomere)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0016060"(metarhodopsin inactivation)|go:"GO:0016061"(regulation of light-activated channel activity)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030496"(midbody)|go:"GO:0031475"(myosin V complex)|go:"GO:0031476"(myosin VI complex)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031489"(myosin V binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0042052"(rhabdomere development)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070855"(myosin VI head/neck binding)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR039030|rcsb pdb:1MXE|rcsb pdb:2BBM|rcsb pdb:2BBN|rcsb pdb:2BKH|rcsb pdb:2VAS|rcsb pdb:2X51|rcsb pdb:3GN4|rcsb pdb:3L9I|rcsb pdb:4ANJ|rcsb pdb:4CLN|rcsb pdb:4DBP|rcsb pdb:4DBQ|rcsb pdb:4PJJ|reactome:R-DME-111932|reactome:R-DME-111933|reactome:R-DME-111957|reactome:R-DME-114608|reactome:R-DME-1474151|reactome:R-DME-163615|reactome:R-DME-1855204|reactome:R-DME-2025928|reactome:R-DME-203615|reactome:R-DME-2514859|reactome:R-DME-2871809|reactome:R-DME-4086398|reactome:R-DME-438066|reactome:R-DME-442729|reactome:R-DME-451308|reactome:R-DME-5218920|reactome:R-DME-5578775|reactome:R-DME-5607763|reactome:R-DME-5673000|reactome:R-DME-6798695|reactome:R-DME-70221|reactome:R-DME-8876725|reactome:R-DME-9009391|reactome:R-DME-936837|reactome:R-DME-9619229|reactome:R-DME-9648002 pubmed:9813038(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:up5alvgvMuNIKzKb+pSFOhkX/747227 rogid:YAM6OWzAUWCYzXsvimrlj1fbLl07227 intact-crc:2753BC930C6ADD2B|rigid:G/MOc75GCIQqTqhuiXxagM3L+HY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10676 uniprotkb:P62152 intact:EBI-674492|uniprotkb:P10677|uniprotkb:Q8MRP1|uniprotkb:Q9VM23|uniprotkb:Q9VM24|ensemblmetazoa:FBpp0079064 intact:EBI-182924|uniprotkb:P07181|uniprotkb:Q9V3T4|ensemblmetazoa:FBpp0087109|ensemblmetazoa:FBpp0087110|ensemblmetazoa:FBpp0293502|ensemblmetazoa:FBpp0293503|ensemblmetazoa:FBpp0311269 psi-mi:ninac_drome(display_long)|uniprotkb:ninaC(gene name)|psi-mi:ninaC(display_short)|uniprotkb:CG5125(orf name) psi-mi:calm_drome(display_long)|uniprotkb:Cam(gene name)|psi-mi:Cam(display_short)|uniprotkb:CG8472(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871770 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523503.2|refseq:NP_723271.1|flybase:FBgn0002938|refseq:NP_001260189.1|refseq:NP_001260190.1|interpro:IPR036961|ensemblmetazoa:FBgn0002938(gene)|ensemblmetazoa:FBtr0079436(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0007604"(phototransduction, UV)|go:"GO:0008104"(protein localization)|go:"GO:0009416"(response to light stimulus)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0033227"(dsRNA transport)|go:"GO:0033583"(rhabdomere membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042385"(myosin III complex)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990146"(protein localization to rhabdomere)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020635|interpro:IPR027417 refseq:NP_523710.1|refseq:NP_725120.1|flybase:FBgn0000253|refseq:NP_001286337.1|refseq:NP_001246276.1|refseq:NP_001246277.1|dip:DIP-42091N|ensemblmetazoa:FBgn0000253(gene)|ensemblmetazoa:FBtr0088001(transcript)|ensemblmetazoa:FBtr0088002(transcript)|ensemblmetazoa:FBtr0304963(transcript)|ensemblmetazoa:FBtr0304964(transcript)|ensemblmetazoa:FBtr0345018(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0016028"(rhabdomere)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0016060"(metarhodopsin inactivation)|go:"GO:0016061"(regulation of light-activated channel activity)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030496"(midbody)|go:"GO:0031475"(myosin V complex)|go:"GO:0031476"(myosin VI complex)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031489"(myosin V binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0042052"(rhabdomere development)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070855"(myosin VI head/neck binding)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR039030|rcsb pdb:1MXE|rcsb pdb:2BBM|rcsb pdb:2BBN|rcsb pdb:2BKH|rcsb pdb:2VAS|rcsb pdb:2X51|rcsb pdb:3GN4|rcsb pdb:3L9I|rcsb pdb:4ANJ|rcsb pdb:4CLN|rcsb pdb:4DBP|rcsb pdb:4DBQ|rcsb pdb:4PJJ|reactome:R-DME-111932|reactome:R-DME-111933|reactome:R-DME-111957|reactome:R-DME-114608|reactome:R-DME-1474151|reactome:R-DME-163615|reactome:R-DME-1855204|reactome:R-DME-2025928|reactome:R-DME-203615|reactome:R-DME-2514859|reactome:R-DME-2871809|reactome:R-DME-4086398|reactome:R-DME-438066|reactome:R-DME-442729|reactome:R-DME-451308|reactome:R-DME-5218920|reactome:R-DME-5578775|reactome:R-DME-5607763|reactome:R-DME-5673000|reactome:R-DME-6798695|reactome:R-DME-70221|reactome:R-DME-8876725|reactome:R-DME-9009391|reactome:R-DME-936837|reactome:R-DME-9619229|reactome:R-DME-9648002 pubmed:7556088(see-also)|pubmed:8235618(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:igNic9r58X1xxPMXgTE4sUFkwkE7227 rogid:YAM6OWzAUWCYzXsvimrlj1fbLl07227 intact-crc:FFB8A441EABC9A22|rigid:w4xHxRIQKXeA9lOmSbJ6dHYT2Gw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24008 uniprotkb:P62152 intact:EBI-195326|uniprotkb:Q9NBV3|ensemblmetazoa:FBpp0071820 intact:EBI-182924|uniprotkb:P07181|uniprotkb:Q9V3T4|ensemblmetazoa:FBpp0087109|ensemblmetazoa:FBpp0087110|ensemblmetazoa:FBpp0293502|ensemblmetazoa:FBpp0293503|ensemblmetazoa:FBpp0311269 psi-mi:inad_drome(display_long)|uniprotkb:inaD(gene name)|psi-mi:inaD(display_short)|uniprotkb:CG3504(orf name) psi-mi:calm_drome(display_long)|uniprotkb:Cam(gene name)|psi-mi:Cam(display_short)|uniprotkb:CG8472(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871774 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_726260.1|flybase:FBgn0001263|dip:DIP-18621N|ensemblmetazoa:FBgn0001263(gene)|ensemblmetazoa:FBtr0071909(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008104"(protein localization)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0017022"(myosin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031473"(myosin III binding)|go:"GO:0050962"(detection of light stimulus involved in sensory perception)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rcsb pdb:1IHJ|rcsb pdb:2LA8|rcsb pdb:2QKT|rcsb pdb:2QKU|rcsb pdb:2QKV|rcsb pdb:3R0H|rcsb pdb:5F67|rcsb pdb:6IRE|reactome:R-DME-983168 refseq:NP_523710.1|refseq:NP_725120.1|flybase:FBgn0000253|refseq:NP_001286337.1|refseq:NP_001246276.1|refseq:NP_001246277.1|dip:DIP-42091N|ensemblmetazoa:FBgn0000253(gene)|ensemblmetazoa:FBtr0088001(transcript)|ensemblmetazoa:FBtr0088002(transcript)|ensemblmetazoa:FBtr0304963(transcript)|ensemblmetazoa:FBtr0304964(transcript)|ensemblmetazoa:FBtr0345018(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0016028"(rhabdomere)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0016060"(metarhodopsin inactivation)|go:"GO:0016061"(regulation of light-activated channel activity)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030496"(midbody)|go:"GO:0031475"(myosin V complex)|go:"GO:0031476"(myosin VI complex)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031489"(myosin V binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0042052"(rhabdomere development)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070855"(myosin VI head/neck binding)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR039030|rcsb pdb:1MXE|rcsb pdb:2BBM|rcsb pdb:2BBN|rcsb pdb:2BKH|rcsb pdb:2VAS|rcsb pdb:2X51|rcsb pdb:3GN4|rcsb pdb:3L9I|rcsb pdb:4ANJ|rcsb pdb:4CLN|rcsb pdb:4DBP|rcsb pdb:4DBQ|rcsb pdb:4PJJ|reactome:R-DME-111932|reactome:R-DME-111933|reactome:R-DME-111957|reactome:R-DME-114608|reactome:R-DME-1474151|reactome:R-DME-163615|reactome:R-DME-1855204|reactome:R-DME-2025928|reactome:R-DME-203615|reactome:R-DME-2514859|reactome:R-DME-2871809|reactome:R-DME-4086398|reactome:R-DME-438066|reactome:R-DME-442729|reactome:R-DME-451308|reactome:R-DME-5218920|reactome:R-DME-5578775|reactome:R-DME-5607763|reactome:R-DME-5673000|reactome:R-DME-6798695|reactome:R-DME-70221|reactome:R-DME-8876725|reactome:R-DME-9009391|reactome:R-DME-936837|reactome:R-DME-9619229|reactome:R-DME-9648002 pubmed:9679151(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:A8GcGpwkZoLFwA/GoYkveOsUzC07227 rogid:YAM6OWzAUWCYzXsvimrlj1fbLl07227 intact-crc:20D96182FAB67A7C|rigid:PF8tcQABeH4N3Pmflx62Hm7OpaI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9W3D3 uniprotkb:P62152 intact:EBI-868608|uniprotkb:O96957|uniprotkb:Q8T3K8|uniprotkb:Q9W3D2|ensemblmetazoa:FBpp0071165|ensemblmetazoa:FBpp0089320|ensemblmetazoa:FBpp0310013 intact:EBI-182924|uniprotkb:P07181|uniprotkb:Q9V3T4|ensemblmetazoa:FBpp0087109|ensemblmetazoa:FBpp0087110|ensemblmetazoa:FBpp0293502|ensemblmetazoa:FBpp0293503|ensemblmetazoa:FBpp0311269 psi-mi:crag_drome(display_long)|uniprotkb:Crag(gene name)|psi-mi:Crag(display_short)|uniprotkb:CG12737(orf name)|uniprotkb:Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein(gene name synonym) psi-mi:calm_drome(display_long)|uniprotkb:Cam(gene name)|psi-mi:Cam(display_short)|uniprotkb:CG8472(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871778 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0025864|dip:DIP-59994N|refseq:NP_727281.2|refseq:NP_001162710.2|refseq:NP_525080.3|ensemblmetazoa:FBgn0025864(gene)|ensemblmetazoa:FBgn0025864(gene)|ensemblmetazoa:FBtr0071219(transcript)|ensemblmetazoa:FBtr0071220(transcript)|ensemblmetazoa:FBtr0343356(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032483"(regulation of Rab protein signal transduction)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055037"(recycling endosome)|go:"GO:0061864"(basement membrane constituent secretion)|go:"GO:0070831"(basement membrane assembly)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0110010"(basolateral protein secretion)|go:"GO:0110011"(regulation of basement membrane organization)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR023341|interpro:IPR037516|interpro:IPR043153|reactome:R-DME-8876198|ensemblmetazoa:FBgn0025864(gene) refseq:NP_523710.1|refseq:NP_725120.1|flybase:FBgn0000253|refseq:NP_001286337.1|refseq:NP_001246276.1|refseq:NP_001246277.1|dip:DIP-42091N|ensemblmetazoa:FBgn0000253(gene)|ensemblmetazoa:FBtr0088001(transcript)|ensemblmetazoa:FBtr0088002(transcript)|ensemblmetazoa:FBtr0304963(transcript)|ensemblmetazoa:FBtr0304964(transcript)|ensemblmetazoa:FBtr0345018(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0016028"(rhabdomere)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0016060"(metarhodopsin inactivation)|go:"GO:0016061"(regulation of light-activated channel activity)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030496"(midbody)|go:"GO:0031475"(myosin V complex)|go:"GO:0031476"(myosin VI complex)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031489"(myosin V binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0042052"(rhabdomere development)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070855"(myosin VI head/neck binding)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR039030|rcsb pdb:1MXE|rcsb pdb:2BBM|rcsb pdb:2BBN|rcsb pdb:2BKH|rcsb pdb:2VAS|rcsb pdb:2X51|rcsb pdb:3GN4|rcsb pdb:3L9I|rcsb pdb:4ANJ|rcsb pdb:4CLN|rcsb pdb:4DBP|rcsb pdb:4DBQ|rcsb pdb:4PJJ|reactome:R-DME-111932|reactome:R-DME-111933|reactome:R-DME-111957|reactome:R-DME-114608|reactome:R-DME-1474151|reactome:R-DME-163615|reactome:R-DME-1855204|reactome:R-DME-2025928|reactome:R-DME-203615|reactome:R-DME-2514859|reactome:R-DME-2871809|reactome:R-DME-4086398|reactome:R-DME-438066|reactome:R-DME-442729|reactome:R-DME-451308|reactome:R-DME-5218920|reactome:R-DME-5578775|reactome:R-DME-5607763|reactome:R-DME-5673000|reactome:R-DME-6798695|reactome:R-DME-70221|reactome:R-DME-8876725|reactome:R-DME-9009391|reactome:R-DME-936837|reactome:R-DME-9619229|reactome:R-DME-9648002 pubmed:9813038(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2018/09/18 rogid:ut74u3wVPw2fsMS/h3YLzo9MVf47227 rogid:YAM6OWzAUWCYzXsvimrlj1fbLl07227 intact-crc:C3F243A380926421|rigid:RekWrqAyr0OnyFVl5GlSdABFXzI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KJV6 uniprotkb:Q00168 intact:EBI-867875 intact:EBI-124595|uniprotkb:Q59DP1|uniprotkb:Q59DP2|uniprotkb:Q9V495|ensemblmetazoa:FBpp0099496|ensemblmetazoa:FBpp0289607 psi-mi:q7kjv6_drome(display_long)|uniprotkb:Uba2(gene name)|psi-mi:Uba2(display_short)|uniprotkb:CG7528(orf name) psi-mi:kcc2a_drome(display_long)|uniprotkb:CaMKII(gene name)|psi-mi:CaMKII(display_short)|uniprotkb:CaM(gene name synonym)|uniprotkb:CG18069(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871782 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0029113|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033134"(ubiquitin activating enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR019572|interpro:IPR023318|interpro:IPR028077|interpro:IPR030661|interpro:IPR033127|interpro:IPR035985|interpro:IPR042449 flybase:FBgn0264607|refseq:NP_001162832.1|refseq:NP_001014696.1|refseq:NP_524635.3|refseq:NP_001162831.1|refseq:NP_726633.2|refseq:NP_726634.1|refseq:NP_726635.2|refseq:NP_726636.2|ensemblmetazoa:FBgn0264607(gene)|ensemblmetazoa:FBtr0100146(transcript)|ensemblmetazoa:FBtr0300378(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007611"(learning or memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007619"(courtship behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060278"(regulation of ovulation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:5FG8|rcsb pdb:5H9B|rcsb pdb:5HU3|reactome:R-DME-3371571|reactome:R-DME-4086398|reactome:R-DME-438066|reactome:R-DME-5578775|reactome:R-DME-5673000|reactome:R-DME-936837 pubmed:10995744(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6hSWdsAvG5y2/bW1XcSHzO+1b0A7227 rogid:jUkYZ4jMtpk9BQOvqv7fXANyxNo7227 intact-crc:FD24D3CA7DF4465C|rigid:LaQE4104Vb3nTY5X4IEw9D+5Nu0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O97102 uniprotkb:Q00168 intact:EBI-114439|ensemblmetazoa:FBpp0078984|ensemblmetazoa:FBpp0312327 intact:EBI-124595|uniprotkb:Q59DP1|uniprotkb:Q59DP2|uniprotkb:Q9V495|ensemblmetazoa:FBpp0099496|ensemblmetazoa:FBpp0289607 psi-mi:o97102_drome(display_long)|uniprotkb:smt3(gene name)|psi-mi:smt3(display_short)|uniprotkb:Smt3(gene name synonym)|uniprotkb:DmSUMO-1(gene name synonym)|uniprotkb:Dm0342(gene name synonym)|uniprotkb:DmSmt3(gene name synonym)|uniprotkb:Dmel\CG4494(gene name synonym)|uniprotkb:Dmsmt3(gene name synonym)|uniprotkb:SMT3(gene name synonym)|uniprotkb:SUMO(gene name synonym)|uniprotkb:Sumo(gene name synonym)|uniprotkb:"anon-EST:Posey240"(gene name synonym)|uniprotkb:dSmt3(gene name synonym)|uniprotkb:dsmt3(gene name synonym)|uniprotkb:"l(2)04493"(gene name synonym)|uniprotkb:"l(2)SH0182"(gene name synonym)|uniprotkb:"l(2)SH2 0182"(gene name synonym)|uniprotkb:CG4494(orf name)|uniprotkb:sumo(gene name synonym)|uniprotkb:Dmel_CG4494(orf name) psi-mi:kcc2a_drome(display_long)|uniprotkb:CaMKII(gene name)|psi-mi:CaMKII(display_short)|uniprotkb:CaM(gene name synonym)|uniprotkb:CG18069(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871786 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477411.1|go:"GO:0000940"(outer kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|ensemblmetazoa:FBgn0264922(gene)|ensemblmetazoa:FBtr0079356(transcript)|ensemblmetazoa:FBtr0346716(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016925"(protein sumoylation)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030496"(midbody)|go:"GO:0031386"(protein tag)|go:"GO:0035073"(pupariation)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:O97102|rcsb pdb:2K1F|reactome:R-DME-196791|reactome:R-DME-3065679|reactome:R-DME-3108214|reactome:R-DME-3232118|reactome:R-DME-3899300|reactome:R-DME-4090294|reactome:R-DME-4551638|reactome:R-DME-4570464|reactome:R-DME-4615885|reactome:R-DME-4755510|reactome:R-DME-5696395|refseq:NP_001303312.1|flybase:FBgn0264922 flybase:FBgn0264607|refseq:NP_001162832.1|refseq:NP_001014696.1|refseq:NP_524635.3|refseq:NP_001162831.1|refseq:NP_726633.2|refseq:NP_726634.1|refseq:NP_726635.2|refseq:NP_726636.2|ensemblmetazoa:FBgn0264607(gene)|ensemblmetazoa:FBtr0100146(transcript)|ensemblmetazoa:FBtr0300378(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007611"(learning or memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007619"(courtship behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060278"(regulation of ovulation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:5FG8|rcsb pdb:5H9B|rcsb pdb:5HU3|reactome:R-DME-3371571|reactome:R-DME-4086398|reactome:R-DME-438066|reactome:R-DME-5578775|reactome:R-DME-5673000|reactome:R-DME-936837 pubmed:10995744(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:fqo3Y86DDI0SsWGEfanaOs8qJlk7227 rogid:jUkYZ4jMtpk9BQOvqv7fXANyxNo7227 intact-crc:C178491494DCFEB0|rigid:y05MEghEiyaPWXUkLGqFPm8SIk0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KNM2 uniprotkb:Q00168 intact:EBI-74966|intact:EBI-1627711|ensemblmetazoa:FBpp0077741|ensemblmetazoa:FBpp0077742|ensemblmetazoa:FBpp0301731|ensemblmetazoa:FBpp0301732 intact:EBI-124595|uniprotkb:Q59DP1|uniprotkb:Q59DP2|uniprotkb:Q9V495|ensemblmetazoa:FBpp0099496|ensemblmetazoa:FBpp0289607 psi-mi:q7knm2_drome(display_long)|uniprotkb:lwr(gene name)|psi-mi:lwr(display_short)|uniprotkb:semi(gene name synonym)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:DUbc9(gene name synonym)|uniprotkb:DmUbc9(gene name synonym)|uniprotkb:Dmel\CG3018(gene name synonym)|uniprotkb:Dmubc9(gene name synonym)|uniprotkb:FBgn0010602(gene name synonym)|uniprotkb:Iwr(gene name synonym)|uniprotkb:Lwr(gene name synonym)|uniprotkb:Ubc 9(gene name synonym)|uniprotkb:Ubc-9(gene name synonym)|uniprotkb:UbcD9(gene name synonym)|uniprotkb:dUBC9(gene name synonym)|uniprotkb:dUbc9(gene name synonym)|uniprotkb:dip4(gene name synonym)|uniprotkb:hbl(gene name synonym)|uniprotkb:i105(gene name synonym)|uniprotkb:i56(gene name synonym)|uniprotkb:"l(2)01519"(gene name synonym)|uniprotkb:"l(2)02858"(gene name synonym)|uniprotkb:"l(2)05486"(gene name synonym)|uniprotkb:"l(2)05487"(gene name synonym)|uniprotkb:ubc9(gene name synonym)|uniprotkb:Dmel_CG3018(orf name)|uniprotkb:UBC9(gene name synonym)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:CG3018(orf name) psi-mi:kcc2a_drome(display_long)|uniprotkb:CaMKII(gene name)|psi-mi:CaMKII(display_short)|uniprotkb:CaM(gene name synonym)|uniprotkb:CG18069(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871790 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476978.1|refseq:NP_722637.1|flybase:FBgn0010602|refseq:NP_001259833.1|refseq:NP_001259834.1|ensemblmetazoa:FBgn0010602(gene)|ensemblmetazoa:FBtr0078081(transcript)|ensemblmetazoa:FBtr0078082(transcript)|ensemblmetazoa:FBtr0310028(transcript)|ensemblmetazoa:FBtr0310029(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000940"(outer kinetochore)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007391"(dorsal closure)|go:"GO:0008354"(germ cell migration)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030721"(spectrosome organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033134"(ubiquitin activating enzyme binding)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0035207"(negative regulation of hemocyte proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0140540"(negative regulation melanotic encapsulation of foreign target)|go:"GO:1904677"(positive regulation of somatic stem cell division)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-196791|reactome:R-DME-3108214|reactome:R-DME-3232118|reactome:R-DME-3899300|reactome:R-DME-4090294|reactome:R-DME-4551638|reactome:R-DME-4570464|reactome:R-DME-4615885|reactome:R-DME-4755510|reactome:R-DME-5696395 flybase:FBgn0264607|refseq:NP_001162832.1|refseq:NP_001014696.1|refseq:NP_524635.3|refseq:NP_001162831.1|refseq:NP_726633.2|refseq:NP_726634.1|refseq:NP_726635.2|refseq:NP_726636.2|ensemblmetazoa:FBgn0264607(gene)|ensemblmetazoa:FBtr0100146(transcript)|ensemblmetazoa:FBtr0300378(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007611"(learning or memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007619"(courtship behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060278"(regulation of ovulation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:5FG8|rcsb pdb:5H9B|rcsb pdb:5HU3|reactome:R-DME-3371571|reactome:R-DME-4086398|reactome:R-DME-438066|reactome:R-DME-5578775|reactome:R-DME-5673000|reactome:R-DME-936837 pubmed:10995744(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:0klFCJX3ACVlfPFXyh4vl9degjM7227 rogid:jUkYZ4jMtpk9BQOvqv7fXANyxNo7227 intact-crc:ADB251127A0A5462|rigid:GmyvT68L/rVp1Lnhq3YoywfXazU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P31007 uniprotkb:Q00168 intact:EBI-389374|uniprotkb:Q7KV38|uniprotkb:Q7KV39|uniprotkb:Q7KV40|uniprotkb:Q7YXH8|uniprotkb:Q8SY37|uniprotkb:Q8T0C6|uniprotkb:Q95TF5|uniprotkb:Q9VYZ4|uniprotkb:Q9VYZ5|uniprotkb:Q9VYZ6|uniprotkb:A4V4A8|uniprotkb:A4V4B0|uniprotkb:A8JUR9|uniprotkb:A8JUS0|uniprotkb:C7LAH6|intact:EBI-3430803|ensemblmetazoa:FBpp0089351 intact:EBI-124595|uniprotkb:Q59DP1|uniprotkb:Q59DP2|uniprotkb:Q9V495|ensemblmetazoa:FBpp0099496|ensemblmetazoa:FBpp0289607 psi-mi:dlg1_drome(display_long)|uniprotkb:dlg1(gene name)|psi-mi:dlg1(display_short)|uniprotkb:"l(1)dlg1"(gene name synonym)|uniprotkb:CG1725(orf name) psi-mi:kcc2a_drome(display_long)|uniprotkb:CaMKII(gene name)|psi-mi:CaMKII(display_short)|uniprotkb:CaM(gene name synonym)|uniprotkb:CG18069(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871794 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245623.1|refseq:NP_001096955.1|refseq:NP_001096956.1|refseq:NP_001162719.1|refseq:NP_511120.2|refseq:NP_727518.1|refseq:NP_727519.1|refseq:NP_727520.1|refseq:NP_996402.1|refseq:NP_996403.1|refseq:NP_996404.1|refseq:NP_996405.1|refseq:NP_996406.1|refseq:NP_996407.1|flybase:FBgn0001624|refseq:NP_001259447.1|go:"GO:0007399"(nervous system development)|go:"GO:0007617"(mating behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008104"(protein localization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016336"(establishment or maintenance of polarity of larval imaginal disc epithelium)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030054"(cell junction)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042332"(gravitaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046956"(positive phototaxis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0060581"(cell fate commitment involved in pattern specification)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:3TVT|rcsb pdb:4RP3|rcsb pdb:4RP4|rcsb pdb:4RP5|reactome:R-DME-438066|reactome:R-DME-451308|reactome:R-DME-6794361|reactome:R-DME-8849932|ensemblmetazoa:FBgn0001624(gene)|ensemblmetazoa:FBtr0073488(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0005920"(smooth septate junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007391"(dorsal closure)|dip:DIP-31531N flybase:FBgn0264607|refseq:NP_001162832.1|refseq:NP_001014696.1|refseq:NP_524635.3|refseq:NP_001162831.1|refseq:NP_726633.2|refseq:NP_726634.1|refseq:NP_726635.2|refseq:NP_726636.2|ensemblmetazoa:FBgn0264607(gene)|ensemblmetazoa:FBtr0100146(transcript)|ensemblmetazoa:FBtr0300378(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007611"(learning or memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007619"(courtship behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060278"(regulation of ovulation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:5FG8|rcsb pdb:5H9B|rcsb pdb:5HU3|reactome:R-DME-3371571|reactome:R-DME-4086398|reactome:R-DME-438066|reactome:R-DME-5578775|reactome:R-DME-5673000|reactome:R-DME-936837 pubmed:10458610(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NSQ2GlnRFSHOn1DErzrCGZaeSz47227 rogid:jUkYZ4jMtpk9BQOvqv7fXANyxNo7227 intact-crc:91798BD49CCAF74B|rigid:g3OOD92+vmIc/0Ti9MbVIlh4gUs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P48148 uniprotkb:Q24120 intact:EBI-87246|uniprotkb:Q0E958|uniprotkb:Q9V3J0|ensemblmetazoa:FBpp0086353|ensemblmetazoa:FBpp0086354|ensemblmetazoa:FBpp0086355|ensemblmetazoa:FBpp0086356|ensemblmetazoa:FBpp0089129|ensemblmetazoa:FBpp0089130|uniprotkb:A4UZI6 intact:EBI-868620|uniprotkb:Q9VQV8|ensemblmetazoa:FBpp0077202 psi-mi:rho1_drome(display_long)|uniprotkb:Rho1(gene name)|psi-mi:Rho1(display_short)|uniprotkb:CG8416(orf name) psi-mi:capu_drome(display_long)|uniprotkb:capu(gene name)|psi-mi:capu(display_short)|uniprotkb:CG3399(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871798 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0014020(gene)|ensemblmetazoa:FBtr0087211(transcript)|ensemblmetazoa:FBtr0087212(transcript)|ensemblmetazoa:FBtr0087213(transcript)|ensemblmetazoa:FBtr0087214(transcript)|ensemblmetazoa:FBtr0087216(transcript)|ensemblmetazoa:FBtr0087217(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007349"(cellularization)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007374"(posterior midgut invagination)|go:"GO:0007377"(germ-band extension)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0005737"(cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0070451"(cell hair)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0110020"(regulation of actomyosin structure organization)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-193634|reactome:R-DME-198203|reactome:R-DME-2173791|reactome:R-DME-350368|reactome:R-DME-350407|reactome:R-DME-350480|reactome:R-DME-392451|reactome:R-DME-3928662|reactome:R-DME-3928663|reactome:R-DME-4086400|interpro:IPR001806(Ras GTPase)|reactome:R-DME-416482|reactome:R-DME-416572|reactome:R-DME-4420097|reactome:R-DME-450728|reactome:R-DME-5625740|reactome:R-DME-5627117|reactome:R-DME-5663220|reactome:R-DME-5666185|reactome:R-DME-5689896|reactome:R-DME-6785631|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-8980692|reactome:R-DME-9013405|reactome:R-DME-9035034|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007601"(visual perception)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035006"(melanization defense response)|go:"GO:0035099"(hemocyte migration)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035298"(regulation of Malpighian tubule size)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0042060"(wound healing)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045179"(apical cortex)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046663"(dorsal closure, leading edge cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0035149"(lumen formation, open tracheal system)|refseq:NP_477098.1|refseq:NP_599135.1|refseq:NP_599136.1|refseq:NP_725524.1|refseq:NP_995849.1|refseq:NP_995850.1|flybase:FBgn0014020|dip:DIP-22676N refseq:NP_476966.1|flybase:FBgn0000256|ensemblmetazoa:FBgn0000256(gene)|ensemblmetazoa:FBtr0077513(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007316"(pole plasm RNA localization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0030029"(actin filament-based process)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0045010"(actin nucleation)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0048477"(oogenesis)|interpro:IPR001265(Formin)|interpro:IPR015425(Actin-binding FH2) pubmed:10556060(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:DbVx4weiFRCcGfqdsUQWqWQc0Q47227 rogid:+27OUTZx0ddAN8BGC6wE3Umk6t07227 intact-crc:C91E3FC7E47A57E6|rigid:+YHyriJ8rVWMzw7Ff0rbBbA+DwY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P25843 uniprotkb:Q24120 intact:EBI-156199|uniprotkb:Q3YMV6|uniprotkb:Q9VMJ9|ensemblmetazoa:FBpp0078864|ensemblmetazoa:FBpp0078865|ensemblmetazoa:FBpp0078866|ensemblmetazoa:FBpp0089196|ensemblmetazoa:FBpp0301151|ensemblmetazoa:FBpp0301152 intact:EBI-868620|uniprotkb:Q9VQV8|ensemblmetazoa:FBpp0077202 psi-mi:prof_drome(display_long)|uniprotkb:chic(gene name)|psi-mi:chic(display_short)|uniprotkb:chi(gene name synonym)|uniprotkb:CG9553(orf name)|uniprotkb:Protein chickadee(gene name synonym) psi-mi:capu_drome(display_long)|uniprotkb:capu(gene name)|psi-mi:capu(display_short)|uniprotkb:CG3399(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871802 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245905.1|refseq:NP_001245906.1|go:"GO:0043005"(neuron projection)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0051491"(positive regulation of filopodium assembly)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR036140|refseq:NP_477016.1|refseq:NP_599131.1|refseq:NP_723136.1|refseq:NP_995635.1|flybase:FBgn0000308|ensemblmetazoa:FBgn0000308(gene)|ensemblmetazoa:FBtr0079233(transcript)|ensemblmetazoa:FBtr0079234(transcript)|ensemblmetazoa:FBtr0079235(transcript)|ensemblmetazoa:FBtr0079236(transcript)|ensemblmetazoa:FBtr0309212(transcript)|ensemblmetazoa:FBtr0309213(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007391"(dorsal closure)|go:"GO:0007420"(brain development)|go:"GO:0007436"(larval salivary gland morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0016322"(neuron remodeling)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035193"(larval central nervous system remodeling)|go:"GO:0036098"(male germ-line stem cell population maintenance)|go:"GO:0042060"(wound healing)|go:"GO:0042989"(sequestering of actin monomers)|dip:DIP-22165N refseq:NP_476966.1|flybase:FBgn0000256|ensemblmetazoa:FBgn0000256(gene)|ensemblmetazoa:FBtr0077513(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007316"(pole plasm RNA localization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0030029"(actin filament-based process)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0045010"(actin nucleation)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0048477"(oogenesis)|interpro:IPR001265(Formin)|interpro:IPR015425(Actin-binding FH2) pubmed:8681792(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ixw/iYa5+5l7H5opccmsaYQvuY87227 rogid:+27OUTZx0ddAN8BGC6wE3Umk6t07227 intact-crc:D640A4AC5D27CF57|rigid:jh4hVzFbyTI+EDR9dTxpXYe54CA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q95RV2 uniprotkb:P05205 intact:EBI-104820|uniprotkb:B6UW60|uniprotkb:B6UW70|uniprotkb:B6UW72|uniprotkb:B6UW76|uniprotkb:B6UW79|uniprotkb:B6UW88|uniprotkb:O16046|uniprotkb:O18360|uniprotkb:O18361|uniprotkb:O18362|uniprotkb:O18667|uniprotkb:O18675|uniprotkb:Q7KLS0|uniprotkb:Q7KQE4|uniprotkb:Q7KQE8|uniprotkb:Q9TVU4|uniprotkb:Q9U4P0|uniprotkb:Q9VCB3|intact:EBI-868633|uniprotkb:Q86BN7|ensemblmetazoa:FBpp0083943 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 psi-mi:cav_drome(display_long)|uniprotkb:cav(gene name)|psi-mi:cav(display_short)|uniprotkb:anon fe 1G5(gene name synonym)|uniprotkb:anon1G5(gene name synonym)|uniprotkb:Anonymous fast evolving 1G5(gene name synonym)|uniprotkb:HP1/ORC-associated protein(gene name synonym)|uniprotkb:Hoap(gene name synonym)|uniprotkb:IG5(gene name synonym)|uniprotkb:Protein caravaggio(gene name synonym)|uniprotkb:CG6219(orf name) psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871806 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524477.3|refseq:NP_732969.1|refseq:NP_732970.1|refseq:NP_732971.2|flybase:FBgn0026257|dip:DIP-48712N|ensemblmetazoa:FBgn0026257(gene)|ensemblmetazoa:FBtr0084558(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000782"(telomere cap complex)|go:"GO:0005634"(nucleus)|go:"GO:0016233"(telomere capping)|go:"GO:0042162"(telomeric DNA binding)|mint:Q95RV2 refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA pubmed:11408576(see-also) caution:This sequence has been withdrawn from Uniprot.|crc64:FB325B88570FCF0E - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:yMgp2SGwr+YGa/MxFq3nlVoPsuc7227 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 intact-crc:E8D723FA12F8707F|rigid:RR+aoSQCE0UdN5nBAvkiyc93D9s false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O44783 uniprotkb:O46034 intact:EBI-132097|uniprotkb:A4V1F3|uniprotkb:Q6AWR4|uniprotkb:Q9VZP7|ensemblmetazoa:FBpp0073004|ensemblmetazoa:FBpp0073005 intact:EBI-196076|ensemblmetazoa:FBpp0076341 psi-mi:spy_drome(display_long)|uniprotkb:sty(gene name)|psi-mi:sty(display_short)|uniprotkb:CG1921(orf name) psi-mi:o46034_drome(display_long)|uniprotkb:Cbl(gene name)|psi-mi:Cbl(display_short)|uniprotkb:cbl(gene name synonym)|uniprotkb:CBL(gene name synonym)|uniprotkb:D-Cbl(gene name synonym)|uniprotkb:D-Cbl L(gene name synonym)|uniprotkb:D-CblL(gene name synonym)|uniprotkb:D-cbl(gene name synonym)|uniprotkb:D-cblL(gene name synonym)|uniprotkb:D-cblS(gene name synonym)|uniprotkb:DCbl(gene name synonym)|uniprotkb:Dcbl(gene name synonym)|uniprotkb:Dmel\CG7037(gene name synonym)|uniprotkb:Dv-Cbl(gene name synonym)|uniprotkb:Dv-cbl(gene name synonym)|uniprotkb:F165(gene name synonym)|uniprotkb:anon-WO0118547.68(gene name synonym)|uniprotkb:d-cbl(gene name synonym)|uniprotkb:dCbl(gene name synonym)|uniprotkb:v-Cbl(gene name synonym)|uniprotkb:Dmel_CG7037(orf name)|uniprotkb:CG7043(gene name synonym)|uniprotkb:CG7037(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871810 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523902.2|refseq:NP_728881.1|flybase:FBgn0014388|ensemblmetazoa:FBgn0014388(gene)|ensemblmetazoa:FBtr0073145(transcript)|ensemblmetazoa:FBtr0073146(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0021782"(glial cell development)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045314"(regulation of compound eye photoreceptor development)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0055001"(muscle cell development)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0110109"(negative regulation of imaginal disc-derived wing vein specification)|interpro:IPR007875(Sprouty)|reactome:R-DME-1295596|reactome:R-DME-182971|go:"GO:0120177"(negative regulation of torso signaling pathway)|dip:DIP-17914N refseq:NP_729382.1|flybase:FBgn0020224|ensemblmetazoa:FBgn0020224(gene)|ensemblmetazoa:FBtr0076614(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032353"(negative regulation of hormone biosynthetic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045121"(membrane raft)|go:"GO:0047690"(aspartyltransferase activity)|go:"GO:0048134"(germ-line cyst formation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520 pubmed:11053437(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Epk95p/MSvHN+VVqzKqaTdmoO6g7227 rogid:VOO4Uf45gJLXccr2jq5WDTnd3Sk7227 intact-crc:2B44F7BB4CB64D27|rigid:2lk5R3slCmSoeMSA/kRCM0aK7yw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P04412 uniprotkb:O46034 intact:EBI-197863|uniprotkb:O18370|uniprotkb:O61601|uniprotkb:P81868|uniprotkb:Q9W2G0|ensemblmetazoa:FBpp0071571 intact:EBI-196076|ensemblmetazoa:FBpp0076341 psi-mi:egfr_drome(display_long)|uniprotkb:Egfr(gene name)|psi-mi:Egfr(display_short)|uniprotkb:top(gene name synonym)|uniprotkb:DER(gene name synonym)|uniprotkb:c-erbB(gene name synonym)|uniprotkb:CG10079(orf name)|uniprotkb:Gurken receptor(gene name synonym)|uniprotkb:Protein torpedo(gene name synonym)|uniprotkb:Drosophila relative of ERBB(gene name synonym) psi-mi:o46034_drome(display_long)|uniprotkb:Cbl(gene name)|psi-mi:Cbl(display_short)|uniprotkb:cbl(gene name synonym)|uniprotkb:CBL(gene name synonym)|uniprotkb:D-Cbl(gene name synonym)|uniprotkb:D-Cbl L(gene name synonym)|uniprotkb:D-CblL(gene name synonym)|uniprotkb:D-cbl(gene name synonym)|uniprotkb:D-cblL(gene name synonym)|uniprotkb:D-cblS(gene name synonym)|uniprotkb:DCbl(gene name synonym)|uniprotkb:Dcbl(gene name synonym)|uniprotkb:Dmel\CG7037(gene name synonym)|uniprotkb:Dv-Cbl(gene name synonym)|uniprotkb:Dv-cbl(gene name synonym)|uniprotkb:F165(gene name synonym)|uniprotkb:anon-WO0118547.68(gene name synonym)|uniprotkb:d-cbl(gene name synonym)|uniprotkb:dCbl(gene name synonym)|uniprotkb:v-Cbl(gene name synonym)|uniprotkb:Dmel_CG7037(orf name)|uniprotkb:CG7043(gene name synonym)|uniprotkb:CG7037(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871814 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476759.1|flybase:FBgn0003731|dip:DIP-17316N|ensemblmetazoa:FBgn0003731(gene)|ensemblmetazoa:FBtr0071654(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003015"(heart process)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007431"(salivary gland development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007477"(notum development)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007482"(haltere development)|go:"GO:0008071"(maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008355"(olfactory learning)|go:"GO:0008406"(gonad development)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0022008"(neurogenesis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035310"(notum cell fate specification)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|mint:P04412|rcsb pdb:3I2T|rcsb pdb:3LTF|rcsb pdb:3LTG|reactome:R-DME-1227986|reactome:R-DME-1250196|reactome:R-DME-1251985|reactome:R-DME-1253288|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-177929|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-1963642|reactome:R-DME-212718|reactome:R-DME-2179392|reactome:R-DME-416572|reactome:R-DME-5673001|reactome:R-DME-6785631|reactome:R-DME-6811558|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-9018519|reactome:R-DME-9652282 refseq:NP_729382.1|flybase:FBgn0020224|ensemblmetazoa:FBgn0020224(gene)|ensemblmetazoa:FBtr0076614(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032353"(negative regulation of hormone biosynthetic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045121"(membrane raft)|go:"GO:0047690"(aspartyltransferase activity)|go:"GO:0048134"(germ-line cyst formation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520 pubmed:9121472(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Ae9kedh1v+TZ5zG4QorNPm9/FgA7227 rogid:VOO4Uf45gJLXccr2jq5WDTnd3Sk7227 intact-crc:19469E553A3A464A|rigid:YCZa48L5hbewzBHYwzXgHuhyJHE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P54350 uniprotkb:P23572 intact:EBI-188100|uniprotkb:Q9VM70|ensemblmetazoa:FBpp0078999|ensemblmetazoa:FBpp0304607 intact:EBI-108689|intact:EBI-1627558|uniprotkb:A0ANT1|uniprotkb:Q86FT5|uniprotkb:Q86FT6|uniprotkb:Q86FT7|uniprotkb:Q86FT8|uniprotkb:Q86FT9|uniprotkb:Q9TX68|uniprotkb:Q9TX69|uniprotkb:Q9TX70|uniprotkb:Q9TX71|uniprotkb:Q9TX72|uniprotkb:Q9TX73|uniprotkb:Q9TX74|uniprotkb:Q9VKX5|ensemblmetazoa:FBpp0079641 psi-mi:wee1_drome(display_long)|uniprotkb:Wee1(gene name)|psi-mi:Wee1(display_short)|uniprotkb:wee(gene name synonym)|uniprotkb:CG4488(orf name) psi-mi:cdk1_drome(display_long)|uniprotkb:Cdk1(gene name)|psi-mi:Cdk1(display_short)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:cdc2(gene name synonym)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:CG5363(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871818 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477035.1|flybase:FBgn0011737|refseq:NP_001260167.1|dip:DIP-23536N|ensemblmetazoa:FBgn0011737(gene)|ensemblmetazoa:FBtr0079371(transcript)|ensemblmetazoa:FBtr0332329(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017164(Wee1-like protein kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-156711|reactome:R-DME-69202|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-69656|reactome:R-DME-75035 refseq:NP_476797.1|flybase:FBgn0004106|dip:DIP-649N|ensemblmetazoa:FBgn0004106(gene)|ensemblmetazoa:FBtr0080051(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045169"(fusome)|go:"GO:0048142"(germarium-derived cystoblast division)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P23572|reactome:R-DME-110056|reactome:R-DME-174048|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-5687128|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166 pubmed:8573790(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:u81smrgil9W+VwmcCsvlg4HM9VM7227 rogid:WK4kxTRU/nlh6/LCeihCplHOZ2o7227 intact-crc:007D99ABE33E0F4F|rigid:f1egTLtD2+m8mp9XWtNPG/QEft4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P23572 uniprotkb:P20240 intact:EBI-108689|intact:EBI-1627558|uniprotkb:A0ANT1|uniprotkb:Q86FT5|uniprotkb:Q86FT6|uniprotkb:Q86FT7|uniprotkb:Q86FT8|uniprotkb:Q86FT9|uniprotkb:Q9TX68|uniprotkb:Q9TX69|uniprotkb:Q9TX70|uniprotkb:Q9TX71|uniprotkb:Q9TX72|uniprotkb:Q9TX73|uniprotkb:Q9TX74|uniprotkb:Q9VKX5|ensemblmetazoa:FBpp0079641 intact:EBI-115143|uniprotkb:Q9V8E5|ensemblmetazoa:FBpp0085947 psi-mi:cdk1_drome(display_long)|uniprotkb:Cdk1(gene name)|psi-mi:Cdk1(display_short)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:cdc2(gene name synonym)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:CG5363(orf name) psi-mi:ote_drome(display_long)|uniprotkb:Ote(gene name)|psi-mi:Ote(display_short)|uniprotkb:LEM domain-containing protein Otefin(gene name synonym)|uniprotkb:CG5581(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871822 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476797.1|flybase:FBgn0004106|dip:DIP-649N|ensemblmetazoa:FBgn0004106(gene)|ensemblmetazoa:FBtr0080051(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045169"(fusome)|go:"GO:0048142"(germarium-derived cystoblast division)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P23572|reactome:R-DME-110056|reactome:R-DME-174048|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-5687128|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166 ensemblmetazoa:FBgn0266420(gene)|ensemblmetazoa:FBtr0086768(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048477"(oogenesis)|go:"GO:0051301"(cell division)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|flybase:FBgn0266420|refseq:NP_476664.2 pubmed:9199347(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:WK4kxTRU/nlh6/LCeihCplHOZ2o7227 rogid:aKtK7UUuUQFU0zncT/4tjZEpE5k7227 intact-crc:B9AE55A5046CE64A|rigid:GeMjbHeXJ4gS8Jexhf4KcwJIbWk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P02299 uniprotkb:P23572 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 intact:EBI-108689|intact:EBI-1627558|uniprotkb:A0ANT1|uniprotkb:Q86FT5|uniprotkb:Q86FT6|uniprotkb:Q86FT7|uniprotkb:Q86FT8|uniprotkb:Q86FT9|uniprotkb:Q9TX68|uniprotkb:Q9TX69|uniprotkb:Q9TX70|uniprotkb:Q9TX71|uniprotkb:Q9TX72|uniprotkb:Q9TX73|uniprotkb:Q9TX74|uniprotkb:Q9VKX5|ensemblmetazoa:FBpp0079641 psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:cdk1_drome(display_long)|uniprotkb:Cdk1(gene name)|psi-mi:Cdk1(display_short)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:cdc2(gene name synonym)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:CG5363(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871826 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231 refseq:NP_476797.1|flybase:FBgn0004106|dip:DIP-649N|ensemblmetazoa:FBgn0004106(gene)|ensemblmetazoa:FBtr0080051(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045169"(fusome)|go:"GO:0048142"(germarium-derived cystoblast division)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P23572|reactome:R-DME-110056|reactome:R-DME-174048|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-5687128|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166 pubmed:9585509(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 rogid:WK4kxTRU/nlh6/LCeihCplHOZ2o7227 intact-crc:10AAE087AD3AAE25|rigid:8/EkJyW6OpHgqKlH5p5MOQTwFEY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P14785 uniprotkb:P23572 intact:EBI-240333|uniprotkb:Q8IGR7|uniprotkb:Q9VTP6|uniprotkb:Q9VTP7|ensemblmetazoa:FBpp0075807 intact:EBI-108689|intact:EBI-1627558|uniprotkb:A0ANT1|uniprotkb:Q86FT5|uniprotkb:Q86FT6|uniprotkb:Q86FT7|uniprotkb:Q86FT8|uniprotkb:Q86FT9|uniprotkb:Q9TX68|uniprotkb:Q9TX69|uniprotkb:Q9TX70|uniprotkb:Q9TX71|uniprotkb:Q9TX72|uniprotkb:Q9TX73|uniprotkb:Q9TX74|uniprotkb:Q9VKX5|ensemblmetazoa:FBpp0079641 psi-mi:ccna_drome(display_long)|uniprotkb:CycA(gene name)|psi-mi:CycA(display_short)|uniprotkb:CG5940(orf name) psi-mi:cdk1_drome(display_long)|uniprotkb:Cdk1(gene name)|psi-mi:Cdk1(display_short)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:cdc2(gene name synonym)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:CG5363(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871838 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524030.2|flybase:FBgn0000404|dip:DIP-22019N|ensemblmetazoa:FBgn0000404(gene)|ensemblmetazoa:FBtr0076075(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045169"(fusome)|go:"GO:0045170"(spectrosome)|go:"GO:0045202"(synapse)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0097124"(cyclin A2-CDK2 complex)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P14785|reactome:R-DME-1538133|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-5689880|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69273|reactome:R-DME-69563|reactome:R-DME-69656 refseq:NP_476797.1|flybase:FBgn0004106|dip:DIP-649N|ensemblmetazoa:FBgn0004106(gene)|ensemblmetazoa:FBtr0080051(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045169"(fusome)|go:"GO:0048142"(germarium-derived cystoblast division)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P23572|reactome:R-DME-110056|reactome:R-DME-174048|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-5687128|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166 pubmed:11027291(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Ym2ygZ2vFqtDFvZiyifYjRJ7K5c7227 rogid:WK4kxTRU/nlh6/LCeihCplHOZ2o7227 intact-crc:555D0996CFD52DB3|rigid:H1J319fh96mAocweFPHm6IY3uSs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24472 uniprotkb:P23573 intact:EBI-145741|uniprotkb:O77272|uniprotkb:Q961U8|ensemblmetazoa:FBpp0070141 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 psi-mi:rbf_drome(display_long)|uniprotkb:Rbf(gene name)|psi-mi:Rbf(display_short)|uniprotkb:CG7413(orf name) psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871846 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525036.2|flybase:FBgn0015799|dip:DIP-34025N|ensemblmetazoa:FBgn0015799(gene)|ensemblmetazoa:FBtr0070146(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007113"(endomitotic cell cycle)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008361"(regulation of cell size)|reactome:R-DME-69231|reactome:R-DME-2173796|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0030154"(cell differentiation)|go:"GO:0031523"(Myb complex)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042594"(response to starvation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:1900117"(regulation of execution phase of apoptosis)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|reactome:R-DME-1538133|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage) refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N pubmed:8675008(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Z0pdwbec8RKtU9vh7XTH1yrBrHs7227 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 intact-crc:F319066FF0A82C1C|rigid:Cm27nNCyh3WZxw6odO+D4jW3WQs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24159 uniprotkb:P23573 intact:EBI-455799|intact:EBI-1629390 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 psi-mi:q24159_drome(display_long)|uniprotkb:CycJ(gene name)|psi-mi:CycJ(display_short)|uniprotkb:CG10308(orf name) psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871850 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0010317|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0060966"(regulation of gene silencing by RNA)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361 refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N pubmed:11071782(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:v0+u1HylNkW8beHZZmGfAIjkczo7227 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 intact-crc:702A703A0682FACF|rigid:CLKkZwct3U4X1B0pfglUfHlxzN8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P54733 uniprotkb:P23573 intact:EBI-203549|intact:EBI-1628120|uniprotkb:Q24479|uniprotkb:Q95RP5|uniprotkb:Q9V3B3|uniprotkb:Q9V456|ensemblmetazoa:FBpp0080331|ensemblmetazoa:FBpp0080332|ensemblmetazoa:FBpp0080333|ensemblmetazoa:FBpp0080334 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 psi-mi:ccne_drome(display_long)|uniprotkb:CycE(gene name)|psi-mi:CycE(display_short)|uniprotkb:CG3938(orf name) psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871854 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476959.1|refseq:NP_476960.1|refseq:NP_723924.1|refseq:NP_723925.1|refseq:NP_723926.1|flybase:FBgn0010382|dip:DIP-18331N|ensemblmetazoa:FBgn0010382(gene)|ensemblmetazoa:FBtr0080773(transcript)|ensemblmetazoa:FBtr0080774(transcript)|ensemblmetazoa:FBtr0080775(transcript)|ensemblmetazoa:FBtr0080776(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007277"(pole cell development)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035736"(cell proliferation involved in compound eye morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048665"(neuron fate specification)|go:"GO:0090210"(regulation of establishment of blood-brain barrier)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P54733|reactome:R-DME-1538133|reactome:R-DME-187577|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-9706019 refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N pubmed:7797073(see-also)|pubmed:9691043(see-also)|pubmed:8156587(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:AwK/vwBDPgICbmeNxOxrcsj5kiQ7227 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 intact-crc:028383F2628717E4|rigid:seq1AFQiH4TAcrfE+SB8QHu9ba0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P14785 uniprotkb:P23573 intact:EBI-240333|uniprotkb:Q8IGR7|uniprotkb:Q9VTP6|uniprotkb:Q9VTP7|ensemblmetazoa:FBpp0075807 intact:EBI-95916|intact:EBI-1627637|uniprotkb:Q0KI40|uniprotkb:Q9TXB2|uniprotkb:Q9VDJ4|ensemblmetazoa:FBpp0083329|ensemblmetazoa:FBpp0083330|ensemblmetazoa:FBpp0289675 psi-mi:ccna_drome(display_long)|uniprotkb:CycA(gene name)|psi-mi:CycA(display_short)|uniprotkb:CG5940(orf name) psi-mi:cdk2_drome(display_long)|uniprotkb:Cdk2(gene name)|psi-mi:Cdk2(display_short)|uniprotkb:Cell division control protein 2 cognate(gene name synonym)|uniprotkb:cdc2c(gene name synonym)|uniprotkb:CG10498(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871862 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524030.2|flybase:FBgn0000404|dip:DIP-22019N|ensemblmetazoa:FBgn0000404(gene)|ensemblmetazoa:FBtr0076075(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045169"(fusome)|go:"GO:0045170"(spectrosome)|go:"GO:0045202"(synapse)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0097124"(cyclin A2-CDK2 complex)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P14785|reactome:R-DME-1538133|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-5689880|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69273|reactome:R-DME-69563|reactome:R-DME-69656 refseq:NP_001163666.1|refseq:NP_524420.1|refseq:NP_732544.1|flybase:FBgn0004107|ensemblmetazoa:FBgn0004107(gene)|ensemblmetazoa:FBtr0083921(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblmetazoa:FBtr0300447(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-1538133|reactome:R-DME-176187|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-69656|reactome:R-DME-9616222|ensemblmetazoa:FBtr0083922(transcript)|dip:DIP-648N pubmed:11027291(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Ym2ygZ2vFqtDFvZiyifYjRJ7K5c7227 rogid:PFQ6DWcVE9kINQT+XsO0c7ROMLc7227 intact-crc:414C0996D4A4EDD8|rigid:OKzAis9pqtREO1LlTdUCwku3kSk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9U1K1 uniprotkb:P40793 intact:EBI-91672|intact:EBI-867570|intact:EBI-499570|uniprotkb:Q9VIN3|uniprotkb:Q9VIN4|uniprotkb:Q5U0Z8|uniprotkb:Q8INV3|uniprotkb:Q8INV4|uniprotkb:Q8INV5|uniprotkb:Q8SXP3|uniprotkb:Q8T8P8|uniprotkb:Q9U4F0|uniprotkb:Q9U4F1|ensemblmetazoa:FBpp0080884 intact:EBI-114324|uniprotkb:Q540W4|ensemblmetazoa:FBpp0074520|ensemblmetazoa:FBpp0301153|ensemblmetazoa:FBpp0301154|uniprotkb:Q9U9S3|uniprotkb:Q9U9S4|uniprotkb:Q9U9S5|uniprotkb:Q9U9S6|uniprotkb:Q9V465 psi-mi:spir_drome(display_long)|uniprotkb:spir(gene name)|psi-mi:spir(display_short)|uniprotkb:p150-Spir(gene name synonym)|uniprotkb:CG10076(orf name) psi-mi:cdc42_drome(display_long)|uniprotkb:CG12530(orf name)|uniprotkb:Cdc42(gene name)|psi-mi:Cdc42(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871870 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001286100.1|refseq:NP_524854.2|refseq:NP_724254.1|refseq:NP_724255.1|refseq:NP_724256.2|flybase:FBgn0003475|ensemblmetazoa:FBgn0003475(gene)|ensemblmetazoa:FBtr0081352(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046907"(intracellular transport)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0048477"(oogenesis)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0007316"(pole plasm RNA localization)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051639"(actin filament network formation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011019(KIND)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030029"(actin filament-based process)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0030036"(actin cytoskeleton organization)|interpro:IPR029901|rcsb pdb:3MMV|rcsb pdb:3MN5|rcsb pdb:3MN6|rcsb pdb:3MN7|rcsb pdb:3MN9|rcsb pdb:3UE5|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030717"(oocyte karyosome formation)|rcsb pdb:4EFH|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045010"(actin nucleation)|refseq:NP_001246102.1|dip:DIP-17301N refseq:NP_001245762.1|refseq:NP_001245763.1|refseq:NP_523414.1|flybase:FBgn0010341|go:"GO:0007286"(spermatid development)|go:"GO:0007349"(cellularization)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009611"(response to wounding)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016028"(rhabdomere)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035010"(encapsulation of foreign target)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035318"(imaginal disc-derived wing hair outgrowth)|go:"GO:0042060"(wound healing)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0045202"(synapse)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0030027"(lamellipodium)|ensemblmetazoa:FBgn0010341(gene)|ensemblmetazoa:FBtr0074751(transcript)|ensemblmetazoa:FBtr0309214(transcript)|ensemblmetazoa:FBtr0309215(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007266"(Rho protein signal transduction)|interpro:IPR027417|interpro:IPR037874|reactome:R-DME-114604|reactome:R-DME-182971|reactome:R-DME-2029482|reactome:R-DME-389359|reactome:R-DME-3928662|reactome:R-DME-4420097|reactome:R-DME-525793|reactome:R-DME-5627123|reactome:R-DME-5663220|reactome:R-DME-5687128|reactome:R-DME-8964616|reactome:R-DME-9013148|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-9013406|reactome:R-DME-9013409|reactome:R-DME-9013420|reactome:R-DME-9013424|reactome:R-DME-983231|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051601"(exocyst localization)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097206"(nephrocyte filtration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|dip:DIP-31003N pubmed:10556052(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:d5/uax72i+0dvjWvfORgiCSMjwQ7227 rogid:p1Wn2f2lqp9i9DPM0uMTy/eVs+47227 intact-crc:1DF911243F588F7A|rigid:ZbVZkt/UrXKlEtkysJOMe1rGj9Y false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VI13 uniprotkb:P40793 intact:EBI-74826|intact:EBI-123979|intact:EBI-466309|uniprotkb:Q24190|uniprotkb:Q24213|ensemblmetazoa:FBpp0081211|ensemblmetazoa:FBpp0081212|ensemblmetazoa:FBpp0081213|ensemblmetazoa:FBpp0306606|ensemblmetazoa:FBpp0306611 intact:EBI-114324|uniprotkb:Q540W4|ensemblmetazoa:FBpp0074520|ensemblmetazoa:FBpp0301153|ensemblmetazoa:FBpp0301154|uniprotkb:Q9U9S3|uniprotkb:Q9U9S4|uniprotkb:Q9U9S5|uniprotkb:Q9U9S6|uniprotkb:Q9V465 psi-mi:pak_drome(display_long)|uniprotkb:Pak(gene name)|psi-mi:Pak(display_short)|uniprotkb:DPAK(gene name synonym)|uniprotkb:Dpak1(gene name synonym)|uniprotkb:CG10295(orf name) psi-mi:cdc42_drome(display_long)|uniprotkb:CG12530(orf name)|uniprotkb:Cdc42(gene name)|psi-mi:Cdc42(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871874 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0267698|refseq:NP_001262309.1|refseq:NP_001262313.1|refseq:NP_524681.1|refseq:NP_731073.1|refseq:NP_731074.1|ensemblmetazoa:FBgn0267698(gene)|ensemblmetazoa:FBtr0081714(transcript)|ensemblmetazoa:FBtr0081715(transcript)|ensemblmetazoa:FBtr0081716(transcript)|ensemblmetazoa:FBtr0334539(transcript)|ensemblmetazoa:FBtr0334544(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019991"(septate junction assembly)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936 refseq:NP_001245762.1|refseq:NP_001245763.1|refseq:NP_523414.1|flybase:FBgn0010341|go:"GO:0007286"(spermatid development)|go:"GO:0007349"(cellularization)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009611"(response to wounding)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016028"(rhabdomere)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035010"(encapsulation of foreign target)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035318"(imaginal disc-derived wing hair outgrowth)|go:"GO:0042060"(wound healing)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0045202"(synapse)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0030027"(lamellipodium)|ensemblmetazoa:FBgn0010341(gene)|ensemblmetazoa:FBtr0074751(transcript)|ensemblmetazoa:FBtr0309214(transcript)|ensemblmetazoa:FBtr0309215(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007266"(Rho protein signal transduction)|interpro:IPR027417|interpro:IPR037874|reactome:R-DME-114604|reactome:R-DME-182971|reactome:R-DME-2029482|reactome:R-DME-389359|reactome:R-DME-3928662|reactome:R-DME-4420097|reactome:R-DME-525793|reactome:R-DME-5627123|reactome:R-DME-5663220|reactome:R-DME-5687128|reactome:R-DME-8964616|reactome:R-DME-9013148|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-9013406|reactome:R-DME-9013409|reactome:R-DME-9013420|reactome:R-DME-9013424|reactome:R-DME-983231|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051601"(exocyst localization)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097206"(nephrocyte filtration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|dip:DIP-31003N pubmed:8628256(see-also)|pubmed:11322388(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2021/06/18 rogid:B88kI/CaRk7fc0eQ5+Y4jk4zWwc7227 rogid:p1Wn2f2lqp9i9DPM0uMTy/eVs+47227 intact-crc:7B8449319ECFC64A|rigid:0sfpHTY/pQvOU0Rpt3/prDdSVrg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9W1B0 uniprotkb:P40793 intact:EBI-868659|uniprotkb:O44368|ensemblmetazoa:FBpp0072194 intact:EBI-114324|uniprotkb:Q540W4|ensemblmetazoa:FBpp0074520|ensemblmetazoa:FBpp0301153|ensemblmetazoa:FBpp0301154|uniprotkb:Q9U9S3|uniprotkb:Q9U9S4|uniprotkb:Q9U9S5|uniprotkb:Q9U9S6|uniprotkb:Q9V465 psi-mi:gek_drome(display_long)|uniprotkb:gek(gene name)|psi-mi:gek(display_short)|uniprotkb:CG4012(orf name) psi-mi:cdc42_drome(display_long)|uniprotkb:CG12530(orf name)|uniprotkb:Cdc42(gene name)|psi-mi:Cdc42(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871878 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523837.2|flybase:FBgn0023081|ensemblmetazoa:FBgn0023081(gene)|ensemblmetazoa:FBtr0072287(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR031597|reactome:R-DME-9013149|reactome:R-DME-9013406 refseq:NP_001245762.1|refseq:NP_001245763.1|refseq:NP_523414.1|flybase:FBgn0010341|go:"GO:0007286"(spermatid development)|go:"GO:0007349"(cellularization)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009611"(response to wounding)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016028"(rhabdomere)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035010"(encapsulation of foreign target)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035318"(imaginal disc-derived wing hair outgrowth)|go:"GO:0042060"(wound healing)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0045202"(synapse)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0030027"(lamellipodium)|ensemblmetazoa:FBgn0010341(gene)|ensemblmetazoa:FBtr0074751(transcript)|ensemblmetazoa:FBtr0309214(transcript)|ensemblmetazoa:FBtr0309215(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007266"(Rho protein signal transduction)|interpro:IPR027417|interpro:IPR037874|reactome:R-DME-114604|reactome:R-DME-182971|reactome:R-DME-2029482|reactome:R-DME-389359|reactome:R-DME-3928662|reactome:R-DME-4420097|reactome:R-DME-525793|reactome:R-DME-5627123|reactome:R-DME-5663220|reactome:R-DME-5687128|reactome:R-DME-8964616|reactome:R-DME-9013148|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-9013406|reactome:R-DME-9013409|reactome:R-DME-9013420|reactome:R-DME-9013424|reactome:R-DME-983231|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051601"(exocyst localization)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097206"(nephrocyte filtration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|dip:DIP-31003N pubmed:9371783(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:4pX40IV5kTwIePYFyeIOD+lQtt07227 rogid:p1Wn2f2lqp9i9DPM0uMTy/eVs+47227 intact-crc:A68422AC06E9B0E4|rigid:sRZ6Ord3gJPjjJaD8asMgXQK97A false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VGW6 uniprotkb:O96989 intact:EBI-83298|ensemblmetazoa:FBpp0081756|intact:EBI-466357|uniprotkb:P91676 intact:EBI-156880|ensemblmetazoa:FBpp0070175 psi-mi:mcm5_drome(display_long)|uniprotkb:Mcm5(gene name)|psi-mi:Mcm5(display_short)|uniprotkb:CG4082(orf name)|uniprotkb:Minichromosome maintenance 5 protein(gene name synonym) psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871882 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0017577(gene)|ensemblmetazoa:FBtr0082279(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042555"(MCM complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|refseq:NP_524308.2|flybase:FBgn0017577 refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY pubmed:11024168(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:pE+5Qt9rUBjQz997MqFx67cZ/vI7227 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 intact-crc:E95A77042E421BC8|rigid:25UFsNSNeLgTSUx6kXcc4wqaizg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q26454 uniprotkb:O96989 intact:EBI-175772|uniprotkb:Q9V4M5|ensemblmetazoa:FBpp0088055|ensemblmetazoa:FBpp0311783 intact:EBI-156880|ensemblmetazoa:FBpp0070175 psi-mi:mcm4_drome(display_long)|uniprotkb:dpa(gene name)|psi-mi:dpa(display_short)|uniprotkb:CG1616(orf name)|uniprotkb:Protein disc proliferation abnormal(gene name synonym) psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871886 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477185.1|flybase:FBgn0015929|refseq:NP_001286160.1|dip:DIP-35346N|ensemblmetazoa:FBgn0015929(gene)|ensemblmetazoa:FBtr0088982(transcript)|ensemblmetazoa:FBtr0345797(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY pubmed:11024168(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NPLqbZqr627OjOQE1CaH1sUgciI7227 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 intact-crc:5FE349ABD6685F3D|rigid:+8iL3fN1fUoUyNotKMTnE0fktYA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24472 uniprotkb:Q94877 intact:EBI-145741|uniprotkb:O77272|uniprotkb:Q961U8|ensemblmetazoa:FBpp0070141 intact:EBI-868679 psi-mi:rbf_drome(display_long)|uniprotkb:Rbf(gene name)|psi-mi:Rbf(display_short)|uniprotkb:CG7413(orf name) psi-mi:q94877_drome(display_long)|uniprotkb:Cdk4(gene name)|psi-mi:Cdk4(display_short)|uniprotkb:cdk4/6(gene name synonym)|uniprotkb:CG5072(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871890 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525036.2|flybase:FBgn0015799|dip:DIP-34025N|ensemblmetazoa:FBgn0015799(gene)|ensemblmetazoa:FBtr0070146(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007113"(endomitotic cell cycle)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008361"(regulation of cell size)|reactome:R-DME-69231|reactome:R-DME-2173796|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0030154"(cell differentiation)|go:"GO:0031523"(Myb complex)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042594"(response to starvation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:1900117"(regulation of execution phase of apoptosis)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|reactome:R-DME-1538133|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage) flybase:FBgn0016131|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016592"(mediator complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) pubmed:10970847(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Z0pdwbec8RKtU9vh7XTH1yrBrHs7227 rogid:8JM799y0XwD+lMIfhTsjcsHN2PQ7227 intact-crc:249551A16CBCB69B|rigid:XgyEMx7z1K+lGO4/79IIcT5H4Gk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24158 uniprotkb:Q94877 intact:EBI-868643 intact:EBI-868679 psi-mi:q24158_drome(display_long)|uniprotkb:CycD(gene name)|psi-mi:CycD(display_short)|uniprotkb:CG9096(orf name) psi-mi:q94877_drome(display_long)|uniprotkb:Cdk4(gene name)|psi-mi:Cdk4(display_short)|uniprotkb:cdk4/6(gene name synonym)|uniprotkb:CG5072(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871894 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0010315|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015451(Cyclin D)|interpro:IPR036915|interpro:IPR039361 flybase:FBgn0016131|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016592"(mediator complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) pubmed:10970847(see-also)|pubmed:10970848(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:9qaYO0eTtTj6bFqv1hrTtqdN8LM7227 rogid:8JM799y0XwD+lMIfhTsjcsHN2PQ7227 intact-crc:BBAC59AEB0EFE32B|rigid:kUpuITU7857feOSN/mRMAdOAVTo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P04052 uniprotkb:Q9VT57 intact:EBI-173525|uniprotkb:Q9VYX6|ensemblmetazoa:FBpp0073387 intact:EBI-163640|uniprotkb:P91642|uniprotkb:Q8MS41|ensemblmetazoa:FBpp0076098 psi-mi:rpb1_drome(display_long)|uniprotkb:RpII215(gene name)|psi-mi:RpII215(display_short)|uniprotkb:CG1554(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym) psi-mi:cdk8_drome(display_long)|uniprotkb:Cdk8(gene name)|psi-mi:Cdk8(display_short)|uniprotkb:CG10572(orf name)|uniprotkb:Cell division protein kinase 8(gene name synonym)|uniprotkb:Mediator of RNA polymerase II transcription subunit Cdk8(gene name synonym)|uniprotkb:Mediator complex subunit Cdk8(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871898 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511124.1|flybase:FBgn0003277|dip:DIP-22282N|ensemblmetazoa:FBgn0003277(gene)|ensemblmetazoa:FBtr0073542(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|reactome:R-DME-112382|reactome:R-DME-113418|reactome:R-DME-674695|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-6782210|reactome:R-DME-6796648|reactome:R-DME-6803529|reactome:R-DME-6807505|reactome:R-DME-72086|reactome:R-DME-72163|reactome:R-DME-72165|reactome:R-DME-72203|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-75955|reactome:R-DME-76042|reactome:R-DME-77075|reactome:R-DME-9018519 refseq:NP_536735.2|flybase:FBgn0015618|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0022416"(chaeta development)|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0045498"(sex comb development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensemblmetazoa:FBgn0015618(gene)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9VT57|reactome:R-DME-2173796|ensemblmetazoa:FBtr0076369(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|dip:DIP-38574N pubmed:8730095(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:15kW36zkVzQkXGBb5/mQk4h4lSM7227 rogid:SfbQn3dRgHofURgYqE6dFxhkznY7227 intact-crc:B74448ECA2D2B07D|rigid:Lnz9lvvWE8Dm3U3OUopiD7EMVkc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P25008 uniprotkb:Q9VT57 intact:EBI-195485|intact:EBI-1627425|uniprotkb:Q9VFF1|ensemblmetazoa:FBpp0082469 intact:EBI-163640|uniprotkb:P91642|uniprotkb:Q8MS41|ensemblmetazoa:FBpp0076098 psi-mi:ccnc_drome(display_long)|uniprotkb:CycC(gene name)|psi-mi:CycC(display_short)|uniprotkb:CLND(gene name synonym)|uniprotkb:CG7281(orf name) psi-mi:cdk8_drome(display_long)|uniprotkb:Cdk8(gene name)|psi-mi:Cdk8(display_short)|uniprotkb:CG10572(orf name)|uniprotkb:Cell division protein kinase 8(gene name synonym)|uniprotkb:Mediator of RNA polymerase II transcription subunit Cdk8(gene name synonym)|uniprotkb:Mediator complex subunit Cdk8(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871902 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476848.1|flybase:FBgn0004597|dip:DIP-17706N|ensemblmetazoa:FBgn0004597(gene)|ensemblmetazoa:FBtr0083010(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0022416"(chaeta development)|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0045498"(sex comb development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028367|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|mint:P25008|reactome:R-DME-2173796 refseq:NP_536735.2|flybase:FBgn0015618|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0022416"(chaeta development)|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0045498"(sex comb development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensemblmetazoa:FBgn0015618(gene)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9VT57|reactome:R-DME-2173796|ensemblmetazoa:FBtr0076369(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|dip:DIP-38574N pubmed:8730095(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:3mNLFE+mOj60/HiqJck7MMMCdys7227 rogid:SfbQn3dRgHofURgYqE6dFxhkznY7227 intact-crc:96EF031812C36D9C|rigid:ZoGHJVNvG+jHsuT1LNOWNrTu5eQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O96433 uniprotkb:O17432 intact:EBI-191577|uniprotkb:Q9VVI6|ensemblmetazoa:FBpp0074968|ensemblmetazoa:FBpp0305335 intact:EBI-100284|ensemblmetazoa:FBpp0071848 psi-mi:ccnt_drome(display_long)|uniprotkb:CycT(gene name)|psi-mi:CycT(display_short)|uniprotkb:CG6292(orf name) psi-mi:o17432_drome(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:CDK9(gene name synonym)|uniprotkb:Dmel\CG5179(gene name synonym)|uniprotkb:P-TEF(gene name synonym)|uniprotkb:P-TEFb(gene name synonym)|uniprotkb:PTefb(gene name synonym)|uniprotkb:cdk9(gene name synonym)|uniprotkb:CG5179(orf name)|uniprotkb:Dmel_CG5179(orf name)|uniprotkb:DmP-TEFb(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871906 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524127.2|refseq:NP_996117.1|flybase:FBgn0025455|refseq:NP_001261992.1|refseq:NP_001261993.1|dip:DIP-29892N|ensemblmetazoa:FBgn0025455(gene)|ensemblmetazoa:FBtr0075205(transcript)|ensemblmetazoa:FBtr0333124(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007419"(ventral cord development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0009408"(response to heat)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032783"(super elongation complex)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|reactome:R-DME-112382|reactome:R-DME-2173796|reactome:R-DME-674695|reactome:R-DME-6796648|reactome:R-DME-6807505|reactome:R-DME-75955|reactome:R-DME-9018519 refseq:NP_477226.2|flybase:FBgn0019949|ensemblmetazoa:FBgn0019949(gene)|ensemblmetazoa:FBtr0071937(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009408"(response to heat)|go:"GO:0016592"(mediator complex)|go:"GO:0032783"(super elongation complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-112382|reactome:R-DME-2173796|reactome:R-DME-674695|reactome:R-DME-6796648|reactome:R-DME-6807505|reactome:R-DME-9018519|reactome:R-DME-75955 pubmed:7759473(see-also)|pubmed:9593731(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ETtMNDDCR0XQyrwPvavX7lDPdaA7227 rogid:vXCTz3FqzBzErQwfX0A9kybDIak7227 intact-crc:6DC517D61B4A6E17|rigid:nLkhNnNl/FZBc+0gwjxwHjUHV7M false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O02194 uniprotkb:Q9VEN1 intact:EBI-255741|uniprotkb:O02395|uniprotkb:O76802|uniprotkb:O96340|uniprotkb:Q9TY80|uniprotkb:Q9V3L9|uniprotkb:Q9V3S1|ensemblmetazoa:FBpp0077850|ensemblmetazoa:FBpp0305666 intact:EBI-133626|uniprotkb:Q7KJX2|uniprotkb:Q9U4I3|uniprotkb:Q9U6C0|uniprotkb:Q7KKC2|uniprotkb:Q9GQV1|uniprotkb:Q9U6C1|intact:EBI-868700|intact:EBI-3422596|ensemblmetazoa:FBpp0088478 psi-mi:psn_drome(display_long)|uniprotkb:Psn(gene name)|psi-mi:Psn(display_short)|uniprotkb:PS(gene name synonym)|uniprotkb:CG18803(orf name)|uniprotkb:dPS(gene name synonym) psi-mi:flna_drome(display_long)|uniprotkb:cher(gene name)|psi-mi:cher(display_short)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Filamin1(gene name synonym)|uniprotkb:cheerio(gene name synonym)|uniprotkb:sko(gene name synonym)|uniprotkb:CG3937(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871918 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0284421|refseq:NP_524184.1|refseq:NP_730535.1|refseq:NP_001262110.1|refseq:NP_001262111.1|dip:DIP-1139N|ensemblmetazoa:FBgn0284421(gene)|ensemblmetazoa:FBtr0078192(transcript)|ensemblmetazoa:FBtr0333479(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006508"(proteolysis)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0009986"(cell surface)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030018"(Z disc)|go:"GO:0030426"(growth cone)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035333"(Notch receptor processing, ligand-dependent)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0070765"(gamma-secretase complex)|interpro:IPR001108(Peptidase A22A, presenilin)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR042524|reactome:R-DME-1251985|reactome:R-DME-3928665|reactome:R-DME-6798695 refseq:NP_524383.3|flybase:FBgn0014141|refseq:NP_732207.1|refseq:NP_001262656.1|go:"GO:0045214"(sarcomere organization)|ensemblmetazoa:FBgn0014141(gene)|ensemblmetazoa:FBtr0089471(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007616"(long-term memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008104"(protein localization)|go:"GO:0008302"(female germline ring canal formation, actin assembly)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030725"(germline ring canal formation)|go:"GO:0035182"(female germline ring canal outer rim)|go:"GO:0035183"(female germline ring canal inner rim)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0035324"(female germline ring canal)|go:"GO:0045179"(apical cortex)|go:"GO:0051015"(actin filament binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051764"(actin crosslink formation)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|reactome:R-DME-114608|reactome:R-DME-446353|reactome:R-DME-5627123|go:"GO:0110069"(syncytial embryo cellularization) pubmed:10984440(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:UZooKoj+G0I4jZIcHgX+55Nlw887227 rogid:++xPEeu5Z1ZaL+pF0/UcA7kK7kE7227 intact-crc:2F4191E0A1ECD6E8|rigid:BQosnedPkkIlbbHbqYVoJQUZwc4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08970 uniprotkb:O18353 intact:EBI-101373|uniprotkb:Q0KI74|uniprotkb:Q9VFK9|ensemblmetazoa:FBpp0082404|ensemblmetazoa:FBpp0082405|ensemblmetazoa:FBpp0301708 intact:EBI-130074|ensemblmetazoa:FBpp0072100 psi-mi:suhw_drome(display_long)|uniprotkb:"su(Hw)"(gene name)|psi-mi:"su(Hw)"(display_short)|uniprotkb:CG8573(orf name) psi-mi:o18353_drome(display_long)|uniprotkb:Chi(gene name)|psi-mi:Chi(display_short)|uniprotkb:Chip(gene name synonym)|uniprotkb:CHIP(gene name synonym)|uniprotkb:Dmel\CG3924(gene name synonym)|uniprotkb:LDB(gene name synonym)|uniprotkb:Ldb(gene name synonym)|uniprotkb:chi(gene name synonym)|uniprotkb:chip(gene name synonym)|uniprotkb:dLDB(gene name synonym)|uniprotkb:dLdb(gene name synonym)|uniprotkb:"l(2)04405"(gene name synonym)|uniprotkb:"l(2)k04405"(gene name synonym)|uniprotkb:CG3924(orf name)|uniprotkb:Dmel_CG3924(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871922 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001247098.1|refseq:NP_524349.1|refseq:NP_731897.1|flybase:FBgn0003567|ensemblmetazoa:FBgn0003567(gene)|ensemblmetazoa:FBtr0082945(transcript)|ensemblmetazoa:FBtr0082946(transcript)|ensemblmetazoa:FBtr0310002(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035075"(response to ecdysone)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1990188"(euchromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P08970|dip:DIP-17895N refseq:NP_477082.1|flybase:FBgn0013764|ensemblmetazoa:FBgn0013764(gene)|ensemblmetazoa:FBtr0072191(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007563"(regulation of eclosion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030274"(LIM domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070983"(dendrite guidance)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|go:"GO:0010468"(regulation of gene expression) pubmed:10688916(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+ilEJg0b+kjTjvxxkEZDNwSTMpg7227 rogid:czIwVtaJWBnWCANwkEZHnvpMrn87227 intact-crc:4E8CF6920F3C6252|rigid:cVyE/Cefri4Ctg898i5ZpGljsXM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P52168 uniprotkb:O18353 intact:EBI-144873|ensemblmetazoa:FBpp0082675 intact:EBI-130074|ensemblmetazoa:FBpp0072100 psi-mi:pnr_drome(display_long)|uniprotkb:pnr(gene name)|psi-mi:pnr(display_short)|uniprotkb:GATA-A(gene name synonym)|uniprotkb:CG3978(orf name)|uniprotkb:Transcription factor GATA-A(gene name synonym)|uniprotkb:dGATA-A(gene name synonym)|uniprotkb:Protein pannier(gene name synonym) psi-mi:o18353_drome(display_long)|uniprotkb:Chi(gene name)|psi-mi:Chi(display_short)|uniprotkb:Chip(gene name synonym)|uniprotkb:CHIP(gene name synonym)|uniprotkb:Dmel\CG3924(gene name synonym)|uniprotkb:LDB(gene name synonym)|uniprotkb:Ldb(gene name synonym)|uniprotkb:chi(gene name synonym)|uniprotkb:chip(gene name synonym)|uniprotkb:dLDB(gene name synonym)|uniprotkb:dLdb(gene name synonym)|uniprotkb:"l(2)04405"(gene name synonym)|uniprotkb:"l(2)k04405"(gene name synonym)|uniprotkb:CG3924(orf name)|uniprotkb:Dmel_CG3924(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871926 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476685.1|flybase:FBgn0003117|ensemblmetazoa:FBgn0003117(gene)|ensemblmetazoa:FBtr0083221(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007510"(cardioblast cell fate determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0022416"(chaeta development)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035051"(cardiocyte differentiation)|go:"GO:0042440"(pigment metabolic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048542"(lymph gland development)|go:"GO:0060047"(heart contraction)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|reactome:R-DME-5683826|reactome:R-DME-983231 refseq:NP_477082.1|flybase:FBgn0013764|ensemblmetazoa:FBgn0013764(gene)|ensemblmetazoa:FBtr0072191(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007563"(regulation of eclosion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030274"(LIM domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070983"(dendrite guidance)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|go:"GO:0010468"(regulation of gene expression) pubmed:11090617(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:G0/pi+DhH2ncsNG77KXtUPOrH7M7227 rogid:czIwVtaJWBnWCANwkEZHnvpMrn87227 intact-crc:AD90D2B22AFCCBA9|rigid:vwwfmsWBZKC27oNJUTpOXoZ58QE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P22810 uniprotkb:O18353 intact:EBI-220589|uniprotkb:Q6NNU8|uniprotkb:Q9W3D0|uniprotkb:Q59E69|ensemblmetazoa:FBpp0289383|ensemblmetazoa:FBpp0303737|ensemblmetazoa:FBpp0304127 intact:EBI-130074|ensemblmetazoa:FBpp0072100 psi-mi:hmoc_drome(display_long)|uniprotkb:oc(gene name)|psi-mi:oc(display_short)|uniprotkb:Otd(gene name synonym)|uniprotkb:Protein orthodenticle(gene name synonym)|uniprotkb:CG12154(orf name) psi-mi:o18353_drome(display_long)|uniprotkb:Chi(gene name)|psi-mi:Chi(display_short)|uniprotkb:Chip(gene name synonym)|uniprotkb:CHIP(gene name synonym)|uniprotkb:Dmel\CG3924(gene name synonym)|uniprotkb:LDB(gene name synonym)|uniprotkb:Ldb(gene name synonym)|uniprotkb:chi(gene name synonym)|uniprotkb:chip(gene name synonym)|uniprotkb:dLDB(gene name synonym)|uniprotkb:dLdb(gene name synonym)|uniprotkb:"l(2)04405"(gene name synonym)|uniprotkb:"l(2)k04405"(gene name synonym)|uniprotkb:CG3924(orf name)|uniprotkb:Dmel_CG3924(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871930 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014727.2|flybase:FBgn0004102|refseq:NP_001259345.1|refseq:NP_001259346.1|ensemblmetazoa:FBgn0004102(gene)|ensemblmetazoa:FBtr0300106(transcript)|ensemblmetazoa:FBtr0331305(transcript)|ensemblmetazoa:FBtr0331738(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007355"(anterior region determination)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007420"(brain development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008056"(ocellus development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0035284"(brain segmentation)|go:"GO:0035288"(anterior head segmentation)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042463"(ocellus photoreceptor cell development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045315"(positive regulation of compound eye photoreceptor development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046552"(photoreceptor cell fate commitment)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048816"(ocellus morphogenesis)|go:"GO:0061541"(rhabdomere morphogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970 refseq:NP_477082.1|flybase:FBgn0013764|ensemblmetazoa:FBgn0013764(gene)|ensemblmetazoa:FBtr0072191(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007563"(regulation of eclosion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030274"(LIM domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070983"(dendrite guidance)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|go:"GO:0010468"(regulation of gene expression) pubmed:10688916(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:cEIfEbfubNtfQX7FSi1xo400erg7227 rogid:czIwVtaJWBnWCANwkEZHnvpMrn87227 intact-crc:CD4BDC812D455D4F|rigid:wrTfWeAp9YCXnClF3XY1+LOSXUg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P02835 uniprotkb:O18353 intact:EBI-125786|uniprotkb:O96929|uniprotkb:Q4V6Y3|uniprotkb:Q9V3W3|ensemblmetazoa:FBpp0081139 intact:EBI-130074|ensemblmetazoa:FBpp0072100 psi-mi:ftz_drome(display_long)|uniprotkb:ftz(gene name)|psi-mi:ftz(display_short)|uniprotkb:CG2047(orf name) psi-mi:o18353_drome(display_long)|uniprotkb:Chi(gene name)|psi-mi:Chi(display_short)|uniprotkb:Chip(gene name synonym)|uniprotkb:CHIP(gene name synonym)|uniprotkb:Dmel\CG3924(gene name synonym)|uniprotkb:LDB(gene name synonym)|uniprotkb:Ldb(gene name synonym)|uniprotkb:chi(gene name synonym)|uniprotkb:chip(gene name synonym)|uniprotkb:dLDB(gene name synonym)|uniprotkb:dLdb(gene name synonym)|uniprotkb:"l(2)04405"(gene name synonym)|uniprotkb:"l(2)k04405"(gene name synonym)|uniprotkb:CG3924(orf name)|uniprotkb:Dmel_CG3924(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871934 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477498.1|flybase:FBgn0001077|ensemblmetazoa:FBgn0001077(gene)|ensemblmetazoa:FBtr0081625(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007417"(central nervous system development)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0008354"(germ cell migration)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035282"(segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR005567(Fushi tarazu, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1FTZ|rcsb pdb:2XHS|dip:DIP-18500N refseq:NP_477082.1|flybase:FBgn0013764|ensemblmetazoa:FBgn0013764(gene)|ensemblmetazoa:FBtr0072191(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007563"(regulation of eclosion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030274"(LIM domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070983"(dendrite guidance)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|go:"GO:0010468"(regulation of gene expression) pubmed:10688916(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Kvf67LQf7eGvmUDSnAlxn8/kSwU7227 rogid:czIwVtaJWBnWCANwkEZHnvpMrn87227 intact-crc:0BB6F62BD3E77F08|rigid:SxfWeIZP9VEUeXXPn5FNMbBhMOU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O18683 uniprotkb:Q9XTN2 intact:EBI-136889|uniprotkb:Q95SY4|uniprotkb:Q9VPN6|ensemblmetazoa:FBpp0303635 intact:EBI-176370|uniprotkb:Q5U0V5|uniprotkb:Q9U4G2|uniprotkb:D0UY43|uniprotkb:D0UY45|uniprotkb:D0UY46|uniprotkb:D0UY47|uniprotkb:D0UY49|uniprotkb:D0UY50|uniprotkb:D0UY51|uniprotkb:D0UY52|uniprotkb:D0UY54|uniprotkb:D0UY55|uniprotkb:D0UY61|uniprotkb:D0UY62|uniprotkb:D0UY64|uniprotkb:D0UY65|uniprotkb:D0UY66|uniprotkb:D0UY67|uniprotkb:D0UY68|ensemblmetazoa:FBpp0079677|ensemblmetazoa:FBpp0292907|ensemblmetazoa:FBpp0305604 psi-mi:o18683_drome(display_long)|uniprotkb:Pi3K21B(gene name)|psi-mi:Pi3K21B(display_short)|uniprotkb:droPIK57(gene name synonym)|uniprotkb:p60(gene name synonym)|uniprotkb:CG2699(orf name) psi-mi:irs1_drome(display_long)|uniprotkb:chico(gene name)|psi-mi:chico(display_short)|uniprotkb:IRS(gene name synonym)|uniprotkb:CG5686(orf name)|uniprotkb:Protein chico(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871942 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0020622|ensemblmetazoa:FBgn0020622(gene)|ensemblmetazoa:FBtr0331208(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016301"(kinase activity)|go:"GO:0019900"(kinase binding)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|interpro:IPR000980(SH2 motif)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR036860|reactome:R-DME-110478 refseq:NP_001188772.1|refseq:NP_723540.1|flybase:FBgn0024248|refseq:NP_001260316.1|dip:DIP-23631N|ensemblmetazoa:FBgn0024248(gene)|ensemblmetazoa:FBtr0080088(transcript)|ensemblmetazoa:FBtr0303904(transcript)|ensemblmetazoa:FBtr0333412(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007285"(primary spermatocyte growth)|go:"GO:0007295"(growth of a germarium-derived egg chamber)|go:"GO:0007296"(vitellogenesis)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008355"(olfactory learning)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0034059"(response to anoxia)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0061964"(negative regulation of entry into reproductive diapause)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-DME-109704|reactome:R-DME-110478|reactome:R-DME-112399|reactome:R-DME-112412|reactome:R-DME-1257604|reactome:R-DME-198203|reactome:R-DME-5673001|reactome:R-DME-6811558|reactome:R-DME-74749|reactome:R-DME-9027276|reactome:R-DME-9027284 pubmed:12163412(see-also)|pubmed:10801879(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:cdOgMluWy8oZsnsqWrhsxv1GfSg7227 rogid:ewOZtT+2P14/RsctVcnrQEmQEjY7227 intact-crc:EB0F9A4D15BA3AA1|rigid:2IEHTmcQsCQzcM+rR7HILPtWzoc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q08012 uniprotkb:Q9XTN2 intact:EBI-161391|uniprotkb:Q0E989|uniprotkb:Q9V6Q5|uniprotkb:A4UZF9|ensemblmetazoa:FBpp0086813|ensemblmetazoa:FBpp0086814|ensemblmetazoa:FBpp0086815|ensemblmetazoa:FBpp0086816|ensemblmetazoa:FBpp0086817 intact:EBI-176370|uniprotkb:Q5U0V5|uniprotkb:Q9U4G2|uniprotkb:D0UY43|uniprotkb:D0UY45|uniprotkb:D0UY46|uniprotkb:D0UY47|uniprotkb:D0UY49|uniprotkb:D0UY50|uniprotkb:D0UY51|uniprotkb:D0UY52|uniprotkb:D0UY54|uniprotkb:D0UY55|uniprotkb:D0UY61|uniprotkb:D0UY62|uniprotkb:D0UY64|uniprotkb:D0UY65|uniprotkb:D0UY66|uniprotkb:D0UY67|uniprotkb:D0UY68|ensemblmetazoa:FBpp0079677|ensemblmetazoa:FBpp0292907|ensemblmetazoa:FBpp0305604 psi-mi:grap_drome(display_long)|uniprotkb:drk(gene name)|psi-mi:drk(display_short)|uniprotkb:"E(sev)2B"(gene name synonym)|uniprotkb:Downstream of receptor kinase(gene name synonym)|uniprotkb:Grb2(gene name synonym)|uniprotkb:Protein enhancer of sevenless 2B(gene name synonym)|uniprotkb:CG6033(orf name) psi-mi:irs1_drome(display_long)|uniprotkb:chico(gene name)|psi-mi:chico(display_short)|uniprotkb:IRS(gene name synonym)|uniprotkb:CG5686(orf name)|uniprotkb:Protein chico(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871946 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476858.1|refseq:NP_725302.1|refseq:NP_725303.1|refseq:NP_725304.1|refseq:NP_725306.1|flybase:FBgn0004638|ensemblmetazoa:FBgn0004638(gene)|ensemblmetazoa:FBtr0087694(transcript)|ensemblmetazoa:FBtr0087695(transcript)|ensemblmetazoa:FBtr0087696(transcript)|ensemblmetazoa:FBtr0087697(transcript)|ensemblmetazoa:FBtr0087698(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005118"(sevenless binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007614"(short-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR030219|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2A36|go:"GO:0008306"(associative learning)|rcsb pdb:2A37|rcsb pdb:2AZS|rcsb pdb:2AZV|reactome:R-DME-109704|reactome:R-DME-112412|reactome:R-DME-1250347|reactome:R-DME-1257604|reactome:R-DME-1295596|reactome:R-DME-1433557|reactome:R-DME-1433559|reactome:R-DME-167044|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-1963642|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2428933|reactome:R-DME-2730905|reactome:R-DME-2871796|reactome:R-DME-2871809|reactome:R-DME-375165|reactome:R-DME-5654688|go:"GO:0008355"(olfactory learning)|reactome:R-DME-5654689|reactome:R-DME-5654693|reactome:R-DME-5654695|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654710|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5654720|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5673001|reactome:R-DME-6811558|reactome:R-DME-74749|reactome:R-DME-74751|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-9027284|reactome:R-DME-912631|reactome:R-DME-9607240|reactome:R-DME-983695|reactome:R-DME-5654733|dip:DIP-21223N refseq:NP_001188772.1|refseq:NP_723540.1|flybase:FBgn0024248|refseq:NP_001260316.1|dip:DIP-23631N|ensemblmetazoa:FBgn0024248(gene)|ensemblmetazoa:FBtr0080088(transcript)|ensemblmetazoa:FBtr0303904(transcript)|ensemblmetazoa:FBtr0333412(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007285"(primary spermatocyte growth)|go:"GO:0007295"(growth of a germarium-derived egg chamber)|go:"GO:0007296"(vitellogenesis)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008355"(olfactory learning)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0034059"(response to anoxia)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0061964"(negative regulation of entry into reproductive diapause)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-DME-109704|reactome:R-DME-110478|reactome:R-DME-112399|reactome:R-DME-112412|reactome:R-DME-1257604|reactome:R-DME-198203|reactome:R-DME-5673001|reactome:R-DME-6811558|reactome:R-DME-74749|reactome:R-DME-9027276|reactome:R-DME-9027284 pubmed:12163412(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:GNPfKX2LH0HRXEW4ASFDTrXN3VY7227 rogid:ewOZtT+2P14/RsctVcnrQEmQEjY7227 intact-crc:C3EBD0BE8EE85A9E|rigid:BJmJaSTm1X7NtnjwRok6Xgl9TWw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q27279 uniprotkb:P19538 intact:EBI-496967 intact:EBI-94976|uniprotkb:O18525|uniprotkb:Q8T6T1|uniprotkb:Q9V4A8|ensemblmetazoa:FBpp0088245 psi-mi:q27279_drome(display_long)|uniprotkb:CG6054(orf name)|uniprotkb:"Su(fu)"(gene name)|psi-mi:"Su(fu)"(display_short)|uniprotkb:suppressor of fused(gene name synonym) psi-mi:ci_drome(display_long)|uniprotkb:ci(gene name)|psi-mi:ci(display_short)|uniprotkb:ci-D(gene name synonym)|uniprotkb:CG2125(orf name)|uniprotkb:ci form of 155 kDa(gene name synonym)|uniprotkb:ci full-length protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871950 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0005355|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-DME-209159|reactome:R-DME-216119 refseq:NP_524617.3|flybase:FBgn0004859|ensemblmetazoa:FBgn0004859(gene)|ensemblmetazoa:FBtr0089178(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002385"(mucosal immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035217"(labial disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043359|rcsb pdb:3HQM|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-209446|reactome:R-DME-216119|reactome:R-DME-216167|reactome:R-DME-216217|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684|go:"GO:0060914"(heart formation)|dip:DIP-121N pubmed:9601642(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:kJht+zz+5JAYtNJQ1IX1hW480e47227 rogid:OECmiJznkWySH07yEHq3R8HSsAQ7227 intact-crc:AE722E9747AD2FDA|rigid:sYJiHOQDY2PcpXOtsJHxff+aljk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18431 uniprotkb:P19538 intact:EBI-242141|uniprotkb:O76881|uniprotkb:P23646|uniprotkb:Q27603|uniprotkb:Q27604|uniprotkb:Q27605|uniprotkb:Q8MRF7|uniprotkb:Q9NF42|uniprotkb:Q9U094|uniprotkb:Q9W4X3|ensemblmetazoa:FBpp0070449|ensemblmetazoa:FBpp0070451|ensemblmetazoa:FBpp0070452|ensemblmetazoa:FBpp0070453|ensemblmetazoa:FBpp0089158|ensemblmetazoa:FBpp0089162 intact:EBI-94976|uniprotkb:O18525|uniprotkb:Q8T6T1|uniprotkb:Q9V4A8|ensemblmetazoa:FBpp0088245 psi-mi:sgg_drome(display_long)|uniprotkb:sgg(gene name)|psi-mi:sgg(display_short)|uniprotkb:zw3(gene name synonym)|uniprotkb:CG2621(orf name)|uniprotkb:Protein zeste-white 3(gene name synonym)|uniprotkb:gsk3(gene name synonym) psi-mi:ci_drome(display_long)|uniprotkb:ci(gene name)|psi-mi:ci(display_short)|uniprotkb:ci-D(gene name synonym)|uniprotkb:CG2125(orf name)|uniprotkb:ci form of 155 kDa(gene name synonym)|uniprotkb:ci full-length protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871954 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476714.1|refseq:NP_476715.1|refseq:NP_476716.2|refseq:NP_599105.1|refseq:NP_726822.1|refseq:NP_726823.1|refseq:NP_996335.1|refseq:NP_996336.1|refseq:NP_996337.1|refseq:NP_996338.1|flybase:FBgn0003371|dip:DIP-39170N|ensemblmetazoa:FBgn0003371(gene)|ensemblmetazoa:FBtr0070466(transcript)|ensemblmetazoa:FBtr0070468(transcript)|ensemblmetazoa:FBtr0070469(transcript)|ensemblmetazoa:FBtr0070470(transcript)|ensemblmetazoa:FBtr0070472(transcript)|ensemblmetazoa:FBtr0070473(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007165"(signal transduction)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007507"(heart development)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008355"(olfactory learning)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0022416"(chaeta development)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030424"(axon)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035324"(female germline ring canal)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045169"(fusome)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046959"(habituation)|go:"GO:0048477"(oogenesis)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070884"(regulation of calcineurin-NFAT signaling cascade)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209387|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3371453|reactome:R-DME-399956|reactome:R-DME-432553|reactome:R-DME-4641262|reactome:R-DME-5610785 refseq:NP_524617.3|flybase:FBgn0004859|ensemblmetazoa:FBgn0004859(gene)|ensemblmetazoa:FBtr0089178(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002385"(mucosal immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035217"(labial disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043359|rcsb pdb:3HQM|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-209446|reactome:R-DME-216119|reactome:R-DME-216167|reactome:R-DME-216217|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684|go:"GO:0060914"(heart formation)|dip:DIP-121N pubmed:11912487(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:sUjAtUAobW55mTZBsRiQg0K1U9o7227 rogid:OECmiJznkWySH07yEHq3R8HSsAQ7227 intact-crc:251844238847536B|rigid:ThA3s209E8tWvHlJnfkJ/60/QtI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P12370 uniprotkb:P19538 intact:EBI-82224|uniprotkb:Q9VL99|uniprotkb:A4V0I0|ensemblmetazoa:FBpp0079448|ensemblmetazoa:FBpp0089382|ensemblmetazoa:FBpp0307466 intact:EBI-94976|uniprotkb:O18525|uniprotkb:Q8T6T1|uniprotkb:Q9V4A8|ensemblmetazoa:FBpp0088245 psi-mi:kapc1_drome(display_long)|uniprotkb:Pka-C1(gene name)|psi-mi:Pka-C1(display_short)|uniprotkb:CdkA(gene name synonym)|uniprotkb:DC0(gene name synonym)|uniprotkb:Protein kinase DC0(gene name synonym)|uniprotkb:CG4379(orf name) psi-mi:ci_drome(display_long)|uniprotkb:ci(gene name)|psi-mi:ci(display_short)|uniprotkb:ci-D(gene name synonym)|uniprotkb:CG2125(orf name)|uniprotkb:ci form of 155 kDa(gene name synonym)|uniprotkb:ci full-length protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871958 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0000273(gene)|ensemblmetazoa:FBtr0079851(transcript)|ensemblmetazoa:FBtr0079852(transcript)|ensemblmetazoa:FBtr0335495(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007615"(anesthesia-resistant memory)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008355"(olfactory learning)|go:"GO:0008359"(regulation of bicoid mRNA localization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046823"(negative regulation of nucleocytoplasmic transport)|go:"GO:0048477"(oogenesis)|go:"GO:0048682"(sprouting of injured axon)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P12370|reactome:R-DME-163615|reactome:R-DME-164378|reactome:R-DME-180024|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209360|reactome:R-DME-381676|reactome:R-DME-392517|reactome:R-DME-432040|reactome:R-DME-4420097|reactome:R-DME-442720|reactome:R-DME-5578775|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5621575|reactome:R-DME-983231|refseq:NP_723479.1|refseq:NP_995672.1|flybase:FBgn0000273|refseq:NP_476977.1|dip:DIP-23727N refseq:NP_524617.3|flybase:FBgn0004859|ensemblmetazoa:FBgn0004859(gene)|ensemblmetazoa:FBtr0089178(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002385"(mucosal immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035217"(labial disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043359|rcsb pdb:3HQM|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-209446|reactome:R-DME-216119|reactome:R-DME-216167|reactome:R-DME-216217|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684|go:"GO:0060914"(heart formation)|dip:DIP-121N pubmed:10477300(see-also)|pubmed:9482888(see-also)|pubmed:11454764(see-also)|pubmed:11955435(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:e7pEt3E/V/RB/nj6uqwtAs5u1js7227 rogid:OECmiJznkWySH07yEHq3R8HSsAQ7227 intact-crc:266FCCEF556E1115|rigid:gIptuTtSb4PBfUXdxEFKdgy5Gx0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O01368 uniprotkb:P19538 intact:EBI-868028 intact:EBI-94976|uniprotkb:O18525|uniprotkb:Q8T6T1|uniprotkb:Q9V4A8|ensemblmetazoa:FBpp0088245 psi-mi:o01368_drome(display_long)|uniprotkb:nej(gene name)|psi-mi:nej(display_short)|uniprotkb:CG15319(orf name) psi-mi:ci_drome(display_long)|uniprotkb:ci(gene name)|psi-mi:ci(display_short)|uniprotkb:ci-D(gene name synonym)|uniprotkb:CG2125(orf name)|uniprotkb:ci form of 155 kDa(gene name synonym)|uniprotkb:ci full-length protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871962 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261617|dip:DIP-41329N|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008347"(glial cell migration)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016573"(histone acetylation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0043971"(histone H3-K18 acetylation)|go:"GO:0043974"(histone H3-K27 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043993"("histone acetyltransferase activity (H3-K18 specific)")|go:"GO:0044017"("histone acetyltransferase activity (H3-K27 specific)")|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0098793"(presynapse)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR038547|interpro:IPR043145|mint:O01368 refseq:NP_524617.3|flybase:FBgn0004859|ensemblmetazoa:FBgn0004859(gene)|ensemblmetazoa:FBtr0089178(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002385"(mucosal immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035217"(labial disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043359|rcsb pdb:3HQM|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-209446|reactome:R-DME-216119|reactome:R-DME-216167|reactome:R-DME-216217|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684|go:"GO:0060914"(heart formation)|dip:DIP-121N pubmed:10669739(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:JrQCBD9JpkCR4jgg0/08mthcy5o7227 rogid:OECmiJznkWySH07yEHq3R8HSsAQ7227 intact-crc:C9A1E1074326A5CA|rigid:lhoFXZ1CDGrZGo+K2XBurUya/aw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P23647 uniprotkb:P19538 intact:EBI-165536|ensemblmetazoa:FBpp0074373|uniprotkb:Q26346|uniprotkb:Q26347|uniprotkb:Q27412|uniprotkb:Q9VWR7 intact:EBI-94976|uniprotkb:O18525|uniprotkb:Q8T6T1|uniprotkb:Q9V4A8|ensemblmetazoa:FBpp0088245 psi-mi:fused_drome(display_long)|uniprotkb:fu(gene name)|psi-mi:fu(display_short)|uniprotkb:CG6551(orf name) psi-mi:ci_drome(display_long)|uniprotkb:ci(gene name)|psi-mi:ci(display_short)|uniprotkb:ci-D(gene name synonym)|uniprotkb:CG2125(orf name)|uniprotkb:ci form of 155 kDa(gene name synonym)|uniprotkb:ci full-length protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871966 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0001079(gene)|ensemblmetazoa:FBtr0074602(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007228"(positive regulation of hh target transcription factor activity)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007367"(segment polarity determination)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0005119"(smoothened binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6LPH|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-216119|reactome:R-DME-216217|refseq:NP_477499.1|flybase:FBgn0001079|dip:DIP-492N refseq:NP_524617.3|flybase:FBgn0004859|ensemblmetazoa:FBgn0004859(gene)|ensemblmetazoa:FBtr0089178(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002385"(mucosal immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035217"(labial disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043359|rcsb pdb:3HQM|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-209446|reactome:R-DME-216119|reactome:R-DME-216167|reactome:R-DME-216217|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684|go:"GO:0060914"(heart formation)|dip:DIP-121N pubmed:10825151(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:5KrFb8xuGHpjwIlFMx4AkeD9/m47227 rogid:OECmiJznkWySH07yEHq3R8HSsAQ7227 intact-crc:380048C7D66E4312|rigid:WNQgMeK//ptw2jJWqJcqucWKz7w false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q961T5 uniprotkb:P19538 intact:EBI-868711|ensemblmetazoa:FBpp0077759 intact:EBI-94976|uniprotkb:O18525|uniprotkb:Q8T6T1|uniprotkb:Q9V4A8|ensemblmetazoa:FBpp0088245 psi-mi:q961t5_drome(display_long)|uniprotkb:dbr(gene name)|psi-mi:dbr(display_short)|uniprotkb:"BcDNA:LD26519"(gene name synonym)|uniprotkb:CG11371(orf name) psi-mi:ci_drome(display_long)|uniprotkb:ci(gene name)|psi-mi:ci(display_short)|uniprotkb:ci-D(gene name synonym)|uniprotkb:CG2125(orf name)|uniprotkb:ci form of 155 kDa(gene name synonym)|uniprotkb:ci full-length protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871970 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0067779|ensemblmetazoa:FBgn0067779(gene)|ensemblmetazoa:FBtr0078100(transcript)|go:"GO:0005771"(multivesicular body)|go:"GO:0007616"(long-term memory) refseq:NP_524617.3|flybase:FBgn0004859|ensemblmetazoa:FBgn0004859(gene)|ensemblmetazoa:FBtr0089178(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002385"(mucosal immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035217"(labial disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043359|rcsb pdb:3HQM|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-209446|reactome:R-DME-216119|reactome:R-DME-216167|reactome:R-DME-216217|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684|go:"GO:0060914"(heart formation)|dip:DIP-121N pubmed:12791275(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:zZdRbgoy6U92KWMCozujfM2kVng7227 rogid:OECmiJznkWySH07yEHq3R8HSsAQ7227 intact-crc:A03DEAB50AAEE2FD|rigid:Goe+WRWBhfhFrA8SPUmYmqSStkY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P19538 uniprotkb:O16844 intact:EBI-94976|uniprotkb:O18525|uniprotkb:Q8T6T1|uniprotkb:Q9V4A8|ensemblmetazoa:FBpp0088245 intact:EBI-102069|intact:EBI-868718|intact:EBI-1151174|intact:EBI-497208|uniprotkb:A1Z6X4|uniprotkb:B5RIP3|uniprotkb:Q6AWI9|uniprotkb:Q8IH04|ensemblmetazoa:FBpp0088087|ensemblmetazoa:FBpp0307854 psi-mi:ci_drome(display_long)|uniprotkb:ci(gene name)|psi-mi:ci(display_short)|uniprotkb:ci-D(gene name synonym)|uniprotkb:CG2125(orf name)|uniprotkb:ci form of 155 kDa(gene name synonym)|uniprotkb:ci full-length protein(gene name synonym) psi-mi:cos_drome(display_long)|uniprotkb:cos(gene name)|psi-mi:cos(display_short)|uniprotkb:cos2(gene name synonym)|uniprotkb:costal-2(gene name synonym)|uniprotkb:Kinesin-like protein costal2(gene name synonym)|uniprotkb:CG1708(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871974 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524617.3|flybase:FBgn0004859|ensemblmetazoa:FBgn0004859(gene)|ensemblmetazoa:FBtr0089178(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002385"(mucosal immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035217"(labial disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043359|rcsb pdb:3HQM|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-209446|reactome:R-DME-216119|reactome:R-DME-216167|reactome:R-DME-216217|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684|go:"GO:0060914"(heart formation)|dip:DIP-121N refseq:NP_477092.1|flybase:FBgn0000352|ensemblmetazoa:FBgn0000352(gene)|ensemblmetazoa:FBtr0089015(transcript)|ensemblmetazoa:FBtr0336916(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005119"(smoothened binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0008017"(microtubule binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-216119|reactome:R-DME-216217|refseq:NP_001260765.1|dip:DIP-22550N pubmed:9244297(see-also)|pubmed:9244298(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:OECmiJznkWySH07yEHq3R8HSsAQ7227 rogid:6k5Ur6D1FPXovKN/UUjCoqKajQk7227 intact-crc:DC746FD00FF12163|rigid:8zO1OasPbM30htcthuHAQTpVbqg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P19538 uniprotkb:P54367 intact:EBI-94976|uniprotkb:O18525|uniprotkb:Q8T6T1|uniprotkb:Q9V4A8|ensemblmetazoa:FBpp0088245 intact:EBI-129996|uniprotkb:A4V4D3|uniprotkb:Q0KHT2|uniprotkb:Q9VYK2|ensemblmetazoa:FBpp0073513|ensemblmetazoa:FBpp0073515|ensemblmetazoa:FBpp0289609|ensemblmetazoa:FBpp0309354|ensemblmetazoa:FBpp0311372|ensemblmetazoa:FBpp0311373 psi-mi:ci_drome(display_long)|uniprotkb:ci(gene name)|psi-mi:ci(display_short)|uniprotkb:ci-D(gene name synonym)|uniprotkb:CG2125(orf name)|uniprotkb:ci form of 155 kDa(gene name synonym)|uniprotkb:ci full-length protein(gene name synonym) psi-mi:kc1a_drome(display_long)|uniprotkb:CkIalpha(gene name)|psi-mi:CkIalpha(display_short)|uniprotkb:CKI(gene name synonym)|uniprotkb:CG2028(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871978 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524617.3|flybase:FBgn0004859|ensemblmetazoa:FBgn0004859(gene)|ensemblmetazoa:FBtr0089178(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002385"(mucosal immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035217"(labial disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043359|rcsb pdb:3HQM|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-209446|reactome:R-DME-216119|reactome:R-DME-216167|reactome:R-DME-216217|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684|go:"GO:0060914"(heart formation)|dip:DIP-121N refseq:NP_001162737.1|refseq:NP_511140.1|refseq:NP_727631.1|refseq:NP_727632.1|flybase:FBgn0015024|ensemblmetazoa:FBtr0073680(transcript)|ensemblmetazoa:FBtr0073682(transcript)|ensemblmetazoa:FBtr0300380(transcript)|ensemblmetazoa:FBtr0340408(transcript)|ensemblmetazoa:FBtr0345162(transcript)|ensemblmetazoa:FBtr0345163(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-432553|reactome:R-DME-5610785|reactome:R-DME-5635838|refseq:NP_001285163.1|refseq:NP_001285164.1|ensemblmetazoa:FBgn0015024(gene)|dip:DIP-22041N pubmed:11955435(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:OECmiJznkWySH07yEHq3R8HSsAQ7227 rogid:Ze6yIkD2EQvC/BIhGbjP6MoS8aI7227 intact-crc:3BE589E47D2FD664|rigid:THSvCnixVvc4kQChPLuM2zZdi4U false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16371 uniprotkb:Q9U1H0 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 intact:EBI-98330|uniprotkb:Q9VDN9|uniprotkb:A8JR51|uniprotkb:B5RIQ9|uniprotkb:Q29R05|intact:EBI-9963872|intact:EBI-3428486|ensemblmetazoa:FBpp0293564 psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:cic_drome(display_long)|uniprotkb:Protein fettucine(gene name synonym)|uniprotkb:CG43122(orf name)|uniprotkb:cic(gene name)|psi-mi:cic(display_short)|uniprotkb:fet(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871982 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N refseq:NP_001097843.1|refseq:NP_524992.1|flybase:FBgn0262582|ensemblmetazoa:FBgn0262582(gene)|ensemblmetazoa:FBtr0305027(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007313"(maternal specification of dorsal/ventral axis, oocyte, soma encoded)|go:"GO:0007362"(terminal region determination)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048592"(eye morphogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q9U1H0|dip:DIP-23664N pubmed:10652276(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 rogid:5CzQRrC4vpMc+oNE9O31oQSqqbw7227 intact-crc:02C2DAECDD717F5E|rigid:HyKnZ7V4yba8CAl6NQrZN/V+n2c false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q23977 uniprotkb:Q86M30 intact:EBI-74214|uniprotkb:O18411|uniprotkb:Q8SZ04|uniprotkb:Q8SZZ1|uniprotkb:Q9I7S3|ensemblmetazoa:FBpp0073578 intact:EBI-868743 psi-mi:hep_drome(display_long)|uniprotkb:hep(gene name)|psi-mi:hep(display_short)|uniprotkb:hem(gene name synonym)|uniprotkb:MKK7(gene name synonym)|uniprotkb:CG4353(orf name) psi-mi:q86m30_drome(display_long)|uniprotkb:Cka(gene name)|psi-mi:Cka(display_short)|uniprotkb:CG7392(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871986 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_727661.1|flybase:FBgn0010303|refseq:NP_511142.2|refseq:NP_001259501.1|dip:DIP-30870N|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-209397|reactome:R-DME-209447|reactome:R-DME-350376|go:"GO:0042060"(wound healing)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046528"(imaginal disc fusion)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903688"(positive regulation of border follicle cell migration)|ensemblmetazoa:FBgn0010303(gene)|ensemblmetazoa:FBtr0073747(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007254"(JNK cascade)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007561"(imaginal disc eversion)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0009408"(response to heat)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030424"(axon)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0034769"(basement membrane disassembly)|go:"GO:0035006"(melanization defense response)|go:"GO:0036335"(intestinal stem cell homeostasis) flybase:FBgn0044323|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007391"(dorsal closure)|go:"GO:0016020"(membrane)|go:"GO:0042332"(gravitaxis)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322 pubmed:11865058(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:XTLY74pOC/Mk9P0Rrq5DSUM+K0w7227 rogid:yillGQGzBMxo2d97rey5gJNfNFc7227 intact-crc:4C4B1240EAA05703|rigid:vPJo1vUrNQaPdbVCGX65DQIkBOA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P15348 uniprotkb:P08181 intact:EBI-134105|uniprotkb:Q9VIW2|uniprotkb:Q6NR40|uniprotkb:M9PDQ1|ensemblmetazoa:FBpp0080825|ensemblmetazoa:FBpp0304598 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:top2_drome(display_long)|uniprotkb:Top2(gene name)|psi-mi:Top2(display_short)|uniprotkb:CG10223(orf name)|uniprotkb:DNA topoisomerase II(gene name synonym) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871990 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0284220|refseq:NP_476760.1|refseq:NP_001260580.1|ensemblmetazoa:FBgn0284220(gene)|ensemblmetazoa:FBtr0081287(transcript)|ensemblmetazoa:FBtr0332320(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006342"|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008623"(CHRAC)|go:"GO:0030261"(chromosome condensation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|interpro:IPR020568|interpro:IPR031660|interpro:IPR034157|interpro:IPR036890|reactome:R-DME-4615885 refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N pubmed:8383533(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:EkijDVP5cT0HlKzmQhXsNTYxwms7227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:50C3FD6723FB3CAC|rigid:qpvLdLyTJfb7ZTIqWcVymZkzUaI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VDS6 uniprotkb:P08181 intact:EBI-184542|uniprotkb:Q8MQW1|ensemblmetazoa:FBpp0083263 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:surf6_drome(display_long)|uniprotkb:Surf6(gene name)|psi-mi:Surf6(display_short)|uniprotkb:CG4510(orf name) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871994 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524408.1|flybase:FBgn0038746|dip:DIP-23125N|ensemblmetazoa:FBgn0038746(gene)|ensemblmetazoa:FBtr0083854(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0007419"(ventral cord development)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007019(Surfeit locus 6)|interpro:IPR029190 refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N pubmed:11827179(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:5ff0NWZxjCCoi9CGgJgl+yljHUc7227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:7FD7CF26A306A71D|rigid:+CCJDJfcjnytj1d8TAk64PihVLY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P05205 uniprotkb:P08181 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871998 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N pubmed:10329715(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:3E88D542909A37F6|rigid:MCwiLL2+ss+oEPsqDnWPJo24WAo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24536 uniprotkb:P08181 intact:EBI-142265|uniprotkb:Q24540|uniprotkb:Q9W163|uniprotkb:A4UZV0|ensemblmetazoa:FBpp0072258 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:ssl_drome(display_long)|uniprotkb:Ssl(gene name)|psi-mi:Ssl(display_short)|uniprotkb:CG13591(orf name) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872002 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523848.2|flybase:FBgn0015300|ensemblmetazoa:FBgn0015300(gene)|ensemblmetazoa:FBtr0072351(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991 refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N pubmed:12589803(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:guQV4pPMTc73Dj5MoHy9zIBkKng7227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:372E5BBE2B66A1F0|rigid:XLGgBebjO06udSVxfuPp4upAzxA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P39770 uniprotkb:P08181 intact:EBI-146567|uniprotkb:Q8MSC6|uniprotkb:Q9VKH2|ensemblmetazoa:FBpp0088852 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:salm_drome(display_long)|uniprotkb:salm(gene name)|psi-mi:salm(display_short)|uniprotkb:sal(gene name synonym)|uniprotkb:CG6464(orf name) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872006 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_723670.2|flybase:FBgn0261648|ensemblmetazoa:FBgn0261648(gene)|ensemblmetazoa:FBtr0089913(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007423"(sensory organ development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008584"(male gonad development)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0021782"(glial cell development)|go:"GO:0030539"(male genitalia development)|go:"GO:0035155"(negative regulation of terminal cell fate specification, open tracheal system)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035310"(notum cell fate specification)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0045465"(R8 cell differentiation)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048098"(antennal joint development)|go:"GO:0048644"(muscle organ morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-DME-8943724 refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N pubmed:11827179(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KI1tdyu7/m0UL6dTyptBCisG5cQ7227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:46C129B9BC7AC0C5|rigid:w8Wn3/IqFWSpAMQX3QBUDGJd0Jg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P50887 uniprotkb:P08181 intact:EBI-174190|uniprotkb:Q1EC97|uniprotkb:Q9UAN1|uniprotkb:Q9V3X9|ensemblmetazoa:FBpp0070143 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:rl22_drome(display_long)|uniprotkb:RpL22(gene name)|psi-mi:RpL22(display_short)|uniprotkb:CG7434(orf name) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872010 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477134.1|flybase:FBgn0015288|dip:DIP-19124N|ensemblmetazoa:FBgn0015288(gene)|ensemblmetazoa:FBtr0070148(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|rcsb pdb:4V6W|reactome:R-DME-156827|reactome:R-DME-1799339|reactome:R-DME-72689|reactome:R-DME-72706|reactome:R-DME-975956|reactome:R-DME-975957 refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N pubmed:12379220(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:iKbjVVZrZBoy/ffqYWWMNM+w38U7227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:CD0CCCDDFDD2C18D|rigid:f7UTouagTIOEa14peVfyVlspOT4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24150 uniprotkb:P08181 intact:EBI-603430 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:q24150_drome(display_long)|uniprotkb:Nap1(gene name)|psi-mi:Nap1(display_short)|uniprotkb:CG5330(orf name) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872014 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000723"(telomere maintenance)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0035041"(sperm DNA decondensation)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|flybase:FBgn0015268 refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N pubmed:10547286(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NvLzkn4vQ1SBJDrKk24AE4sFmrI7227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:01852DFA701969CC|rigid:hQ8qxqhrzlyR5y/QZR2t/iwP7AI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P13097 uniprotkb:P08181 intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872018 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N pubmed:15003630(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ko+76awzLWRJNBn06B3PQZWBhf47227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:EC78908E5E9F16D2|rigid:TlF6WY6a0g+gGSobp3P9FxRNOsU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24175 uniprotkb:P08181 intact:EBI-128624|ensemblmetazoa:FBpp0073824 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:q24175_drome(display_long)|uniprotkb:dah(gene name)|psi-mi:dah(display_short)|uniprotkb:Apd(gene name synonym)|uniprotkb:Dah(gene name synonym)|uniprotkb:Dmel\CG6157(gene name synonym)|uniprotkb:"fs(1)dah"(gene name synonym)|uniprotkb:Dmel_CG6157(orf name)|uniprotkb:CG6157(orf name) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872030 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511162.1|flybase:FBgn0015926|ensemblmetazoa:FBgn0015926(gene)|ensemblmetazoa:FBtr0074007(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007349"(cellularization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR043145 refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N pubmed:10712516(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:IIYG0wJu9SF227t5+d7Dux1TNn07227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:EF580FFA06994B8B|rigid:Sb8nvBYFBGfQjGy+LIBY8wLgL5U false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O96863 uniprotkb:P08181 intact:EBI-181456|uniprotkb:Q53XE8|uniprotkb:Q9V919|ensemblmetazoa:FBpp0085590 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:csk2c_drome(display_long)|uniprotkb:CkIIbeta2(gene name)|psi-mi:CkIIbeta2(display_short)|uniprotkb:CG8914(orf name) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872034 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477407.1|flybase:FBgn0026136|dip:DIP-23339N|ensemblmetazoa:FBgn0026136(gene)|ensemblmetazoa:FBtr0086278(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991 refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N pubmed:10329473(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:7KmCw2NoTB6FWasuMWrNrUe2oF07227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:EEA9473664E265B1|rigid:3N6S1zAA4CvacWXlgjDTjOAjGog false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08182 uniprotkb:P08181 intact:EBI-128120|uniprotkb:Q76NS4|uniprotkb:Q9VYU4|ensemblmetazoa:FBpp0089135 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:csk2b_drome(display_long)|uniprotkb:CkIIbeta(gene name)|psi-mi:CkIIbeta(display_short)|uniprotkb:Cask-II-b(gene name synonym)|uniprotkb:CG15224(orf name) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872038 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0000259|refseq:NP_001014731.1|refseq:NP_511131.3|refseq:NP_542940.1|refseq:NP_727561.1|refseq:NP_727562.1|refseq:NP_996415.1|refseq:NP_001245628.1|ensemblmetazoa:FBgn0000259(gene)|ensemblmetazoa:FBtr0073562(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016319"(mushroom body development)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0099523"(presynaptic cytosol)|reactome:R-DME-8934903|interpro:IPR000704(Casein kinase II, regulatory subunit)|reactome:R-DME-8948751|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6798695|reactome:R-DME-6804756|reactome:R-DME-6814122|dip:DIP-17048N refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N pubmed:11874456(see-also)|pubmed:10964752(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xiER9RXJ5YAbvII+LPCvwzp3s/47227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:ABD417645731C06E|rigid:5uwFVAnhkGdV/bC0rfh+8G7r4nE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24161 uniprotkb:P08181 intact:EBI-868757 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:q24161_drome(display_long)|uniprotkb:CkIIalpha-i1(gene name)|psi-mi:CkIIalpha-i1(display_short)|uniprotkb:CG6215(orf name)|uniprotkb:CkII-alpha-i1(gene name synonym) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872042 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0015025|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019901"(protein kinase binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N pubmed:11827180(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NbS2CzBkW6A+kl7nwfli7L4hR1o7227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:EA581EFA6B453BE7|rigid:uajshoVLSj3eIZqT6VLEDeaaPjc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8MSS1 uniprotkb:Q9VJE5 intact:EBI-104383|uniprotkb:Q9W4N7|ensemblmetazoa:FBpp0070596|ensemblmetazoa:FBpp0309608 intact:EBI-226404|uniprotkb:O44929|uniprotkb:Q8INY8|uniprotkb:Q8MSD0|ensemblmetazoa:FBpp0080529 psi-mi:lva_drome(display_long)|uniprotkb:lva(gene name)|psi-mi:lva(display_short)|uniprotkb:CG6450(orf name) psi-mi:cl190_drome(display_long)|uniprotkb:CLIP-190(gene name)|psi-mi:CLIP-190(display_short)|uniprotkb:CG5020(orf name)|uniprotkb:Cytoplasmic linker protein 190(gene name synonym)|uniprotkb:d-CLIP-190(gene name synonym)|uniprotkb:Microtubule-binding protein 190(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872050 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0029688(gene)|ensemblmetazoa:FBtr0070626(transcript)|ensemblmetazoa:FBtr0342740(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051683"(establishment of Golgi localization)|refseq:NP_525064.1|flybase:FBgn0029688|refseq:NP_001284849.1|dip:DIP-17967N refseq:NP_609835.2|refseq:NP_724047.2|refseq:NP_724048.1|flybase:FBgn0020503|dip:DIP-21005N|ensemblmetazoa:FBgn0020503(gene)|ensemblmetazoa:FBtr0080976(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045169"(fusome)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0070854"(myosin VI heavy chain binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR032108|interpro:IPR036859 pubmed:11076973(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:BzWYPT/+O9YU1yEXskdRm5Vq6qo7227 rogid:hOXPy+tlGFyG9tRsG6zL9i8wdvY7227 intact-crc:825B5F91ABCAB5C3|rigid:rJG4bpPswXsBBkClHOTmbpFntXc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q01989 uniprotkb:Q9VJE5 intact:EBI-497752|uniprotkb:A4V3C6|uniprotkb:Q59DV3|uniprotkb:Q59DV4|uniprotkb:Q9VCA4|intact:EBI-3428968|intact:EBI-3425979|ensemblmetazoa:FBpp0084020|ensemblmetazoa:FBpp0290581|ensemblmetazoa:FBpp0290584|ensemblmetazoa:FBpp0290585|ensemblmetazoa:FBpp0306895|intact:EBI-3406544 intact:EBI-226404|uniprotkb:O44929|uniprotkb:Q8INY8|uniprotkb:Q8MSD0|ensemblmetazoa:FBpp0080529 psi-mi:mys9_drome(display_long)|uniprotkb:95F MHC(gene name synonym)|uniprotkb:Protein jaguar(gene name synonym)|uniprotkb:CG5695(orf name)|uniprotkb:jar(gene name)|psi-mi:jar(display_short)|uniprotkb:Mhc95F(gene name synonym) psi-mi:cl190_drome(display_long)|uniprotkb:CLIP-190(gene name)|psi-mi:CLIP-190(display_short)|uniprotkb:CG5020(orf name)|uniprotkb:Cytoplasmic linker protein 190(gene name synonym)|uniprotkb:d-CLIP-190(gene name synonym)|uniprotkb:Microtubule-binding protein 190(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872054 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006997"(nucleus organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007051"(spindle organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007552"(metamorphosis)|go:"GO:0007560"(imaginal disc morphogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008104"(protein localization)|go:"GO:0008363"(larval chitin-based cuticle development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019749"(cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte)|refseq:NP_001014647.2|refseq:NP_001014648.2|refseq:NP_001014649.2|refseq:NP_001014650.2|refseq:NP_524478.4|refseq:NP_732976.1|flybase:FBgn0011225|ensemblmetazoa:FBgn0011225(gene)|ensemblmetazoa:FBtr0084636(transcript)|ensemblmetazoa:FBtr0301367(transcript)|ensemblmetazoa:FBtr0301370(transcript)|ensemblmetazoa:FBtr0301371(transcript)|ensemblmetazoa:FBtr0334872(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|refseq:NP_001262905.1|refseq:NP_001262906.1|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030426"(growth cone)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0031476"(myosin VI complex)|go:"GO:0031982"(vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045172"(germline ring canal)|go:"GO:0045175"(basal protein localization)|go:"GO:0045178"(basal part of cell)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0051015"(actin filament binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0055057"(neuroblast division)|go:"GO:0070856"(myosin VI light chain binding)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0070865"(investment cone)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|reactome:R-DME-190873|reactome:R-DME-9013418|reactome:R-DME-9013420|reactome:R-DME-9013422 refseq:NP_609835.2|refseq:NP_724047.2|refseq:NP_724048.1|flybase:FBgn0020503|dip:DIP-21005N|ensemblmetazoa:FBgn0020503(gene)|ensemblmetazoa:FBtr0080976(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045169"(fusome)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0070854"(myosin VI heavy chain binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR032108|interpro:IPR036859 pubmed:9472041(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:2hiVUfgstRkSFeg2mXMbetLQ+cA7227 rogid:hOXPy+tlGFyG9tRsG6zL9i8wdvY7227 intact-crc:9D891CCC4869462C|rigid:XCXCSztCeS/m9U3F7zE7vkkiQhM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P49021 uniprotkb:O61735 intact:EBI-266295|uniprotkb:O44380|uniprotkb:Q8I037|uniprotkb:Q95U67|uniprotkb:Q9VQR6|uniprotkb:Q9VQR7|intact:EBI-3407510|uniprotkb:M9MRE9|uniprotkb:A4V040|uniprotkb:B7Z007|uniprotkb:B7Z008|uniprotkb:C9QPB7|uniprotkb:Q1WWF5|uniprotkb:Q59E16|intact:EBI-9944820|ensemblmetazoa:FBpp0077256|ensemblmetazoa:FBpp0305454 intact:EBI-143834|uniprotkb:A4V1L9|uniprotkb:A4V1M0|uniprotkb:O76342|uniprotkb:O77137|uniprotkb:Q59E25|uniprotkb:Q9VSB0|ensemblmetazoa:FBpp0099478 psi-mi:tim_drome(display_long)|uniprotkb:tim(gene name)|psi-mi:tim(display_short)|uniprotkb:CG3234(orf name) psi-mi:clock_drome(display_long)|uniprotkb:Clk(gene name)|psi-mi:Clk(display_short)|uniprotkb:jrk(gene name synonym)|uniprotkb:CLOCK(gene name synonym)|uniprotkb:PAS1(gene name synonym)|uniprotkb:dCLOCK(gene name synonym)|uniprotkb:dPAS1(gene name synonym)|uniprotkb:CG7391(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872058 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_722914.3|flybase:FBgn0014396|refseq:NP_722912.3|refseq:NP_722913.3|refseq:NP_001014463.2|refseq:NP_001033872.2|refseq:NP_001137780.2|refseq:NP_001137781.2|refseq:NP_001188686.2|dip:DIP-29425N|ensemblmetazoa:FBgn0014396(gene)|ensemblmetazoa:FBtr0077567(transcript)|ensemblmetazoa:FBtr0333256(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003053"(circadian regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007617"(mating behavior)|go:"GO:0007620"(copulation)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009648"(photoperiodism)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0043111"(replication fork arrest)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0046957"(negative phototaxis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048478"(replication fork protection)|go:"GO:0048512"(circadian behavior)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR006906(Timeless protein)|interpro:IPR007725(Timeless C-terminal)|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 flybase:FBgn0023076|refseq:NP_001014574.1|refseq:NP_001014576.1|refseq:NP_523964.2|dip:DIP-46595N|ensemblmetazoa:FBgn0023076(gene)|ensemblmetazoa:FBtr0100132(transcript)|reactome:R-DME-432524|reactome:R-DME-432560|reactome:R-DME-432620|reactome:R-DME-432626|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003053"(circadian regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR035965|interpro:IPR036638|mint:O61735|reactome:R-DME-432395|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|reactome:R-DME-432408|reactome:R-DME-432501 pubmed:10684876(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:wdN/j17nXo6XpfHUGGSo5zYNhog7227 rogid:JUck6V2PVVXQJ0C6ro+ljBXge7E7227 intact-crc:C685929A52CDD6C5|rigid:c2OfYrnjZUze8pOLvxy5yrnlhBc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07663 uniprotkb:O61735 intact:EBI-496170|uniprotkb:O17483|uniprotkb:O76882|uniprotkb:O76883|uniprotkb:O76884|uniprotkb:O76885|uniprotkb:Q24446|uniprotkb:Q24447|uniprotkb:Q24448|uniprotkb:Q24449|uniprotkb:Q6PVA3|uniprotkb:Q8MLY0|uniprotkb:Q9GN20|uniprotkb:Q9GN51|uniprotkb:Q9GQH9|uniprotkb:Q9GV48|uniprotkb:Q9GV53|uniprotkb:Q9GV54|uniprotkb:Q9GV55|uniprotkb:Q9W4X0|ensemblmetazoa:FBpp0070455 intact:EBI-143834|uniprotkb:A4V1L9|uniprotkb:A4V1M0|uniprotkb:O76342|uniprotkb:O77137|uniprotkb:Q59E25|uniprotkb:Q9VSB0|ensemblmetazoa:FBpp0099478 psi-mi:per_drome(display_long)|uniprotkb:Protein clock-6(gene name synonym)|uniprotkb:per(gene name)|psi-mi:per(display_short)|uniprotkb:CG2647(orf name) psi-mi:clock_drome(display_long)|uniprotkb:Clk(gene name)|psi-mi:Clk(display_short)|uniprotkb:jrk(gene name synonym)|uniprotkb:CLOCK(gene name synonym)|uniprotkb:PAS1(gene name synonym)|uniprotkb:dCLOCK(gene name synonym)|uniprotkb:dPAS1(gene name synonym)|uniprotkb:CG7391(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872062 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525056.2|flybase:FBgn0003068|refseq:NP_001259194.1|dip:DIP-29426N|ensemblmetazoa:FBgn0003068(gene)|ensemblmetazoa:FBtr0070477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001306"(age-dependent response to oxidative stress)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007616"(long-term memory)|go:"GO:0007617"(mating behavior)|go:"GO:0007619"(courtship behavior)|go:"GO:0007620"(copulation)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0044297"(cell body)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0048512"(circadian behavior)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR035965|rcsb pdb:1WA9|rcsb pdb:3GEC|rcsb pdb:3RTY|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432524|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 flybase:FBgn0023076|refseq:NP_001014574.1|refseq:NP_001014576.1|refseq:NP_523964.2|dip:DIP-46595N|ensemblmetazoa:FBgn0023076(gene)|ensemblmetazoa:FBtr0100132(transcript)|reactome:R-DME-432524|reactome:R-DME-432560|reactome:R-DME-432620|reactome:R-DME-432626|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003053"(circadian regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR035965|interpro:IPR036638|mint:O61735|reactome:R-DME-432395|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|reactome:R-DME-432408|reactome:R-DME-432501 pubmed:10684876(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+l/mg+2MJForY5dORYWnWsVAhNI7227 rogid:JUck6V2PVVXQJ0C6ro+ljBXge7E7227 intact-crc:62330A119A07CAB6|rigid:9jrWfZdHpxwCvQik71vCgK/MhfM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O61734 uniprotkb:O61735 intact:EBI-87683|uniprotkb:O76344|uniprotkb:Q1LZ29|uniprotkb:Q540W7|uniprotkb:Q9VW44|ensemblmetazoa:FBpp0074693 intact:EBI-143834|uniprotkb:A4V1L9|uniprotkb:A4V1M0|uniprotkb:O76342|uniprotkb:O77137|uniprotkb:Q59E25|uniprotkb:Q9VSB0|ensemblmetazoa:FBpp0099478 psi-mi:cycl_drome(display_long)|uniprotkb:cyc(gene name)|psi-mi:cyc(display_short)|uniprotkb:CG8727(orf name)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:MOP3(gene name synonym) psi-mi:clock_drome(display_long)|uniprotkb:Clk(gene name)|psi-mi:Clk(display_short)|uniprotkb:jrk(gene name synonym)|uniprotkb:CLOCK(gene name synonym)|uniprotkb:PAS1(gene name synonym)|uniprotkb:dCLOCK(gene name synonym)|uniprotkb:dPAS1(gene name synonym)|uniprotkb:CG7391(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872066 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035965|interpro:IPR036638|mint:O61734|rcsb pdb:5F5Y|rcsb pdb:5F68|rcsb pdb:5F69|rcsb pdb:5F6A|reactome:R-DME-432395|reactome:R-DME-432408|reactome:R-DME-432501|reactome:R-DME-432524|reactome:R-DME-432560|reactome:R-DME-432620|reactome:R-DME-432626|interpro:IPR013767(PAS fold)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|ensemblmetazoa:FBtr0074924(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042594"(response to starvation)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0003053"(circadian regulation of heart rate)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0003677"(DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR011598(Helix-loop-helix DNA-binding)|go:"GO:0005634"(nucleus)|ensemblmetazoa:FBgn0023094(gene)|refseq:NP_524168.2|flybase:FBgn0023094 flybase:FBgn0023076|refseq:NP_001014574.1|refseq:NP_001014576.1|refseq:NP_523964.2|dip:DIP-46595N|ensemblmetazoa:FBgn0023076(gene)|ensemblmetazoa:FBtr0100132(transcript)|reactome:R-DME-432524|reactome:R-DME-432560|reactome:R-DME-432620|reactome:R-DME-432626|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003053"(circadian regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR035965|interpro:IPR036638|mint:O61735|reactome:R-DME-432395|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|reactome:R-DME-432408|reactome:R-DME-432501 pubmed:10684876(see-also)|pubmed:10409723(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:GJqWz9Sb11Oc1nTeQnlltpTZAR07227 rogid:JUck6V2PVVXQJ0C6ro+ljBXge7E7227 intact-crc:27A06100C7FE1877|rigid:aAJSiVy/lT9MElTKa3Gv6XTyDn4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08646 uniprotkb:Q7KNQ9 intact:EBI-119517|uniprotkb:Q9V448|ensemblmetazoa:FBpp0081600 intact:EBI-111569|intact:EBI-2564001|ensemblmetazoa:FBpp0086117|ensemblmetazoa:FBpp0309189 psi-mi:ras1_drome(display_long)|uniprotkb:Ras85D(gene name)|psi-mi:Ras85D(display_short)|uniprotkb:Ras1(gene name synonym)|uniprotkb:CG9375(orf name)|uniprotkb:Dmras85D(gene name synonym) psi-mi:q7knq9_drome(display_long)|uniprotkb:cnk(gene name)|psi-mi:cnk(display_short)|uniprotkb:CNK(gene name synonym)|uniprotkb:Cnk(gene name synonym)|uniprotkb:Dmel\CG6556(gene name synonym)|uniprotkb:EC2-3(gene name synonym)|uniprotkb:EK2-3(gene name synonym)|uniprotkb:anon-WO0140519.129(gene name synonym)|uniprotkb:anon-WO0257455.27(gene name synonym)|uniprotkb:"l(2)k16314"(gene name synonym)|uniprotkb:sag(gene name synonym)|uniprotkb:CG6556(orf name)|uniprotkb:Dmel_CG6556(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872070 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476699.1|flybase:FBgn0003205|ensemblmetazoa:FBgn0003205(gene)|ensemblmetazoa:FBtr0082122(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0001709"(cell fate determination)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0002168"(instar larval development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0019003"(GDP binding)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0000165"(MAPK cascade)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0040008"(regulation of growth)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0051607"(defense response to virus)|go:"GO:0060438"(trachea development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072002"(Malpighian tubule development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-DME-1250347|reactome:R-DME-1433557|reactome:R-DME-171007|reactome:R-DME-179812|reactome:R-DME-180336|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2871796|reactome:R-DME-375165|reactome:R-DME-3928662|reactome:R-DME-4086398|reactome:R-DME-432553|reactome:R-DME-5218921|reactome:R-DME-5621575|reactome:R-DME-5654688|reactome:R-DME-5654693|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5673000|reactome:R-DME-5673001|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-8951936|reactome:R-DME-9607240|reactome:R-DME-9634635|reactome:R-DME-9648002|dip:DIP-23541N refseq:NP_725671.1|refseq:NP_001286524.1|dip:DIP-29738N|flybase:FBgn0286070|ensemblmetazoa:FBgn0286070(gene)|ensemblmetazoa:FBtr0086962(transcript)|ensemblmetazoa:FBtr0340214(transcript)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007362"(terminal region determination)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0051607"(defense response to virus)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017874|interpro:IPR036034|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-432553|reactome:R-DME-5674135 pubmed:10557308(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+9A4GDDFmYKN5famfgTGA+t/y+Y7227 rogid:luUwzC5ziVQ0R3V3gskb0IrPiG47227 intact-crc:117C9BEAA6252634|rigid:ubvnfj/Pdff+L2CGqeCLhV71Qb8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P11346 uniprotkb:Q7KNQ9 intact:EBI-664624|uniprotkb:Q9W4Z3|uniprotkb:Q8I086|uniprotkb:Q8I0D9|uniprotkb:Q8ISE1|uniprotkb:Q8ISE2|uniprotkb:Q8ISE3|uniprotkb:Q9NEH9|uniprotkb:A8JUV5|uniprotkb:Q0KHW7|ensemblmetazoa:FBpp0070385|ensemblmetazoa:FBpp0310458 intact:EBI-111569|intact:EBI-2564001|ensemblmetazoa:FBpp0086117|ensemblmetazoa:FBpp0309189 psi-mi:kraf1_drome(display_long)|uniprotkb:Raf(gene name)|psi-mi:Raf(display_short)|uniprotkb:Protein pole-hole(gene name synonym)|uniprotkb:ph(gene name synonym)|uniprotkb:phl(gene name synonym)|uniprotkb:CG2845(orf name) psi-mi:q7knq9_drome(display_long)|uniprotkb:cnk(gene name)|psi-mi:cnk(display_short)|uniprotkb:CNK(gene name synonym)|uniprotkb:Cnk(gene name synonym)|uniprotkb:Dmel\CG6556(gene name synonym)|uniprotkb:EC2-3(gene name synonym)|uniprotkb:EK2-3(gene name synonym)|uniprotkb:anon-WO0140519.129(gene name synonym)|uniprotkb:anon-WO0257455.27(gene name synonym)|uniprotkb:"l(2)k16314"(gene name synonym)|uniprotkb:sag(gene name synonym)|uniprotkb:CG6556(orf name)|uniprotkb:Dmel_CG6556(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872074 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525047.1|flybase:FBgn0003079|refseq:NP_001096867.3|dip:DIP-29769N|ensemblmetazoa:FBgn0003079(gene)|ensemblmetazoa:FBtr0070401(transcript)|ensemblmetazoa:FBtr0344007(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0002168"(instar larval development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007552"(metamorphosis)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042386"(hemocyte differentiation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029071|reactome:R-DME-1295596|reactome:R-DME-170968|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-432553|reactome:R-DME-5621575|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5675482 refseq:NP_725671.1|refseq:NP_001286524.1|dip:DIP-29738N|flybase:FBgn0286070|ensemblmetazoa:FBgn0286070(gene)|ensemblmetazoa:FBtr0086962(transcript)|ensemblmetazoa:FBtr0340214(transcript)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007362"(terminal region determination)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0051607"(defense response to virus)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017874|interpro:IPR036034|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-432553|reactome:R-DME-5674135 pubmed:11741918(see-also)|pubmed:9814705(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:rbvsd7+5RvYrFoXyonEM6Li84hM7227 rogid:luUwzC5ziVQ0R3V3gskb0IrPiG47227 intact-crc:204A348E7B345042|rigid:1gSofrRfoG9klvaTYReXGeCsV7s false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24170 uniprotkb:Q7KNQ9 intact:EBI-868769 intact:EBI-111569|intact:EBI-2564001|ensemblmetazoa:FBpp0086117|ensemblmetazoa:FBpp0309189 psi-mi:q24170_drome(display_long)|uniprotkb:ksr(gene name)|psi-mi:ksr(display_short)|uniprotkb:CG2899(orf name) psi-mi:q7knq9_drome(display_long)|uniprotkb:cnk(gene name)|psi-mi:cnk(display_short)|uniprotkb:CNK(gene name synonym)|uniprotkb:Cnk(gene name synonym)|uniprotkb:Dmel\CG6556(gene name synonym)|uniprotkb:EC2-3(gene name synonym)|uniprotkb:EK2-3(gene name synonym)|uniprotkb:anon-WO0140519.129(gene name synonym)|uniprotkb:anon-WO0257455.27(gene name synonym)|uniprotkb:"l(2)k16314"(gene name synonym)|uniprotkb:sag(gene name synonym)|uniprotkb:CG6556(orf name)|uniprotkb:Dmel_CG6556(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872078 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0015402|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR025561|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-432553 refseq:NP_725671.1|refseq:NP_001286524.1|dip:DIP-29738N|flybase:FBgn0286070|ensemblmetazoa:FBgn0286070(gene)|ensemblmetazoa:FBtr0086962(transcript)|ensemblmetazoa:FBtr0340214(transcript)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007362"(terminal region determination)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0051607"(defense response to virus)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017874|interpro:IPR036034|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-432553|reactome:R-DME-5674135 pubmed:11741918(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ZsbLCPNIB7ojheTNUv7Htgd7Yrg7227 rogid:luUwzC5ziVQ0R3V3gskb0IrPiG47227 intact-crc:B37B9303EC4A64ED|rigid:qZwUoMBTDbwE5jSkDDfOAVyCyAA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08646 uniprotkb:Q24279 intact:EBI-119517|uniprotkb:Q9V448|ensemblmetazoa:FBpp0081600 intact:EBI-868783 psi-mi:ras1_drome(display_long)|uniprotkb:Ras85D(gene name)|psi-mi:Ras85D(display_short)|uniprotkb:Ras1(gene name synonym)|uniprotkb:CG9375(orf name)|uniprotkb:Dmras85D(gene name synonym) psi-mi:q24279_drome(display_long)|uniprotkb:cno(gene name)|psi-mi:cno(display_short)|uniprotkb:CG42312(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872082 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476699.1|flybase:FBgn0003205|ensemblmetazoa:FBgn0003205(gene)|ensemblmetazoa:FBtr0082122(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0001709"(cell fate determination)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0002168"(instar larval development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0019003"(GDP binding)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0000165"(MAPK cascade)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0040008"(regulation of growth)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0051607"(defense response to virus)|go:"GO:0060438"(trachea development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072002"(Malpighian tubule development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-DME-1250347|reactome:R-DME-1433557|reactome:R-DME-171007|reactome:R-DME-179812|reactome:R-DME-180336|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2871796|reactome:R-DME-375165|reactome:R-DME-3928662|reactome:R-DME-4086398|reactome:R-DME-432553|reactome:R-DME-5218921|reactome:R-DME-5621575|reactome:R-DME-5654688|reactome:R-DME-5654693|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5673000|reactome:R-DME-5673001|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-8951936|reactome:R-DME-9607240|reactome:R-DME-9634635|reactome:R-DME-9648002|dip:DIP-23541N flybase:FBgn0259212|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005524"(ATP binding)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007391"(dorsal closure)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0050839"(cell adhesion molecule binding)|interpro:IPR000159(Ras-association)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR036034|interpro:IPR037977 pubmed:9226438(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+9A4GDDFmYKN5famfgTGA+t/y+Y7227 rogid:Np4YgiiOrn4+9abaGHeA9kUFuso7227 intact-crc:617E95486A0217C3|rigid:TYuZbVaT0RXbzuxJul2i/+MS6OQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08645 uniprotkb:Q24279 intact:EBI-175963|uniprotkb:Q2XYB6|uniprotkb:Q540V3|uniprotkb:Q9V3N0|ensemblmetazoa:FBpp0072746|ensemblmetazoa:FBpp0292253|ensemblmetazoa:FBpp0304917 intact:EBI-868783 psi-mi:rap1_drome(display_long)|uniprotkb:Rap1(gene name)|psi-mi:Rap1(display_short)|uniprotkb:R(gene name synonym)|uniprotkb:RAP(gene name synonym)|uniprotkb:Rap1 GTPase(gene name synonym)|uniprotkb:Ras-like protein 3(gene name synonym)|uniprotkb:ras3(gene name synonym)|uniprotkb:CG1956(orf name) psi-mi:q24279_drome(display_long)|uniprotkb:cno(gene name)|psi-mi:cno(display_short)|uniprotkb:CG42312(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872086 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189023.1|refseq:NP_476857.1|flybase:FBgn0004636|refseq:NP_001261295.1|ensemblmetazoa:FBgn0004636(gene)|ensemblmetazoa:FBtr0072867(transcript)|ensemblmetazoa:FBtr0303154(transcript)|ensemblmetazoa:FBtr0332671(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031252"(cell leading edge)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0045874"(positive regulation of sevenless signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR038851|reactome:R-DME-170968|reactome:R-DME-354192|reactome:R-DME-381676|reactome:R-DME-392517|reactome:R-DME-5674135|reactome:R-DME-6798695 flybase:FBgn0259212|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005524"(ATP binding)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007391"(dorsal closure)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0050839"(cell adhesion molecule binding)|interpro:IPR000159(Ras-association)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR036034|interpro:IPR037977 pubmed:14504224(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:mu2X455U2/v4pF+nXz0kpjvYiA07227 rogid:Np4YgiiOrn4+9abaGHeA9kUFuso7227 intact-crc:F17E216E9E922433|rigid:a9mGVH5Xxi3tZLZrF/PRWpNOj0I false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7K4E2 uniprotkb:Q24279 intact:EBI-868803 intact:EBI-868783 psi-mi:q7k4e2_drome(display_long)|uniprotkb:pyd(gene name)|psi-mi:pyd(display_short)|uniprotkb:CG43140(orf name) psi-mi:q24279_drome(display_long)|uniprotkb:cno(gene name)|psi-mi:cno(display_short)|uniprotkb:CG42312(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872090 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0262614|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005917"(nephrocyte diaphragm)|go:"GO:0007391"(dorsal closure)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008258"(head involution)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0022416"(chaeta development)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030424"(axon)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035156"(fusion cell fate specification)|go:"GO:0035220"(wing disc development)|go:"GO:0036059"(nephrocyte diaphragm assembly)|go:"GO:0045177"(apical part of cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034 flybase:FBgn0259212|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005524"(ATP binding)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007391"(dorsal closure)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0050839"(cell adhesion molecule binding)|interpro:IPR000159(Ras-association)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR036034|interpro:IPR037977 pubmed:9858699(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:BgdNMn3rvKsUz+8OJRoFTaYeNtE7227 rogid:Np4YgiiOrn4+9abaGHeA9kUFuso7227 intact-crc:8BEDD94BF5E4192B|rigid:ILLp/y5Lst4Vy8sOoSZQSWiShR8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O44924 uniprotkb:Q24139 intact:EBI-74797 intact:EBI-118294|uniprotkb:Q9VUT9|ensemblmetazoa:FBpp0075332|ensemblmetazoa:FBpp0305237 psi-mi:o44924_drome(display_long)|uniprotkb:robo1(gene name)|psi-mi:robo1(display_short)|uniprotkb:robo(gene name synonym)|uniprotkb:CG13521(orf name) psi-mi:comm_drome(display_long)|uniprotkb:comm(gene name)|psi-mi:comm(display_short)|uniprotkb:Protein commissureless(gene name synonym)|uniprotkb:CG17943(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872094 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0005631|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0008038"(neuron recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008406"(gonad development)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0070983"(dendrite guidance)|go:"GO:0071666"(Slit-Robo signaling complex)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2VR9|rcsb pdb:2VRA refseq:NP_524095.1|flybase:FBgn0010105|refseq:NP_001261891.1|ensemblmetazoa:FBgn0010105(gene)|ensemblmetazoa:FBtr0075579(transcript)|ensemblmetazoa:FBtr0333023(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0008038"(neuron recognition)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0070983"(dendrite guidance)|go:"GO:0090160"(Golgi to lysosome transport)|interpro:IPR031878|rcsb pdb:2EZ5|dip:DIP-22799N pubmed:12202032(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:uLUQxfvRN9BQCyxNV6w22/4BtGw7227 rogid:XWYmHZwsV9lU9rT5zWoPgzkiOiQ7227 intact-crc:DFF44749C1DAF646|rigid:jb0ekQIrtVGq0fMHBX1m1bqbZqU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VVI3 uniprotkb:Q24139 intact:EBI-498113|uniprotkb:Q7KUR2|uniprotkb:Q8IQR6|uniprotkb:Q95R64|uniprotkb:Q95TQ0|uniprotkb:Q95ZF9|ensemblmetazoa:FBpp0289746 intact:EBI-118294|uniprotkb:Q9VUT9|ensemblmetazoa:FBpp0075332|ensemblmetazoa:FBpp0305237 psi-mi:nedd4_drome(display_long)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym)|uniprotkb:CG7555(orf name)|uniprotkb:Nedd4(gene name)|psi-mi:Nedd4(display_short) psi-mi:comm_drome(display_long)|uniprotkb:comm(gene name)|psi-mi:comm(display_short)|uniprotkb:Protein commissureless(gene name synonym)|uniprotkb:CG17943(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872098 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648993.1|refseq:NP_730282.1|refseq:NP_730283.1|refseq:NP_996116.1|flybase:FBgn0259174|dip:DIP-29040N|ensemblmetazoa:FBgn0259174(gene)|ensemblmetazoa:FBtr0300519(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:1905062"(positive regulation of cardioblast proliferation)|go:"GO:1905306"(positive regulation of cardiac myofibril assembly)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:2EZ5|reactome:R-DME-1253288|reactome:R-DME-2173795|reactome:R-DME-8948747|reactome:R-DME-8948751|reactome:R-DME-983168 refseq:NP_524095.1|flybase:FBgn0010105|refseq:NP_001261891.1|ensemblmetazoa:FBgn0010105(gene)|ensemblmetazoa:FBtr0075579(transcript)|ensemblmetazoa:FBtr0333023(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0008038"(neuron recognition)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0070983"(dendrite guidance)|go:"GO:0090160"(Golgi to lysosome transport)|interpro:IPR031878|rcsb pdb:2EZ5|dip:DIP-22799N pubmed:12165468(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:IIVKUUEjopMfaBBOZWdwdYAUWpQ7227 rogid:XWYmHZwsV9lU9rT5zWoPgzkiOiQ7227 intact-crc:672CCDF9595C4F1E|rigid:CWJnmhgQ/tOj6Flwg7TMOYqik9o false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q94887 uniprotkb:Q9V8R9 intact:EBI-140638|uniprotkb:Q9VTU5|ensemblmetazoa:FBpp0075730 intact:EBI-219125|uniprotkb:Q24440|uniprotkb:Q24441|uniprotkb:Q24442|uniprotkb:Q9V8R8|uniprotkb:Q9V8S0|uniprotkb:A1ZBI0|uniprotkb:Q1WWD0|ensemblmetazoa:FBpp0085697 psi-mi:nrx4_drome(display_long)|uniprotkb:Nrx-IV(gene name)|psi-mi:Nrx-IV(display_short)|uniprotkb:CG6827(orf name)|uniprotkb:Neurexin IV(gene name synonym)|uniprotkb:Nrx(gene name synonym) psi-mi:epb41_drome(display_long)|uniprotkb:cora(gene name)|psi-mi:cora(display_short)|uniprotkb:CG11949(orf name)|uniprotkb:Protein coracle(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872102 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0013997(gene)|ensemblmetazoa:FBtr0075998(transcript)|go:"GO:0003015"(heart process)|go:"GO:0005886"(plasma membrane)|go:"GO:0005919"(pleated septate junction)|go:"GO:0007391"(dorsal closure)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0008104"(protein localization)|go:"GO:0008366"(axon ensheathment)|go:"GO:0016021"(integral component of membrane)|refseq:NP_524034.2|flybase:FBgn0013997|go:"GO:0019991"(septate junction assembly)|go:"GO:0021682"(nerve maturation)|go:"GO:0035151"(regulation of tube size, open tracheal system)|go:"GO:0045202"(synapse)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0061343"(cell adhesion involved in heart morphogenesis)|go:"GO:0072553"(terminal button organization)|go:"GO:0097105"(presynaptic membrane assembly)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup) refseq:NP_523791.2|refseq:NP_725864.1|refseq:NP_725865.1|refseq:NP_725866.1|flybase:FBgn0010434|dip:DIP-20283N|ensemblmetazoa:FBgn0010434(gene)|ensemblmetazoa:FBtr0086509(transcript)|go:"GO:0003015"(heart process)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0005920"(smooth septate junction)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007391"(dorsal closure)|go:"GO:0007527"(adult somatic muscle development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0035151"(regulation of tube size, open tracheal system)|go:"GO:0035321"(maintenance of imaginal disc-derived wing hair orientation)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0061343"(cell adhesion involved in heart morphogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|reactome:R-DME-6794361 pubmed:9508778(see-also)|pubmed:8978610(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:kSDCNYBENTCaLMtF6r5slY5bVAU7227 rogid:oNsHQj2cu7kkPGkLeNEnSxxFleA7227 intact-crc:69CAD852E8B276EE|rigid:AhBg1kzO3U6pWy4pnNd76R5agFQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24367 uniprotkb:Q960M7 intact:EBI-868219 intact:EBI-868817|ensemblmetazoa:FBpp0288915 psi-mi:q24367_drome(display_long)|uniprotkb:insc(gene name)|psi-mi:insc(display_short)|uniprotkb:inscuteable(gene name synonym)|uniprotkb:CG11312(orf name) psi-mi:q960m7_drome(display_long)|uniprotkb:corn(gene name)|psi-mi:corn(display_short)|uniprotkb:CG42278(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0011674|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006403"(RNA localization)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008104"(protein localization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045176"(apical protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039921|rcsb pdb:5A7D flybase:FBgn0259173|ensemblmetazoa:FBgn0259173(gene)|ensemblmetazoa:FBtr0299640(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0008017"(microtubule binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0045921"(positive regulation of exocytosis) pubmed:11707517(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:gqUxZqIF4l7DUDBAs57rDl6o79U7227 rogid:HnSFiop0mEDg8FugjMXD1djzdJw7227 intact-crc:00FFADA74D760DEC|rigid:5TmzfrAmbEzQHJZhScd15K3Ox90 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7K4E2 uniprotkb:O96046 intact:EBI-868803 intact:EBI-868827 psi-mi:q7k4e2_drome(display_long)|uniprotkb:pyd(gene name)|psi-mi:pyd(display_short)|uniprotkb:CG43140(orf name) psi-mi:o96046_drome(display_long)|uniprotkb:Cortactin(gene name)|psi-mi:Cortactin(display_short)|uniprotkb:DCortactin(gene name synonym)|uniprotkb:CG3637(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872110 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0262614|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005917"(nephrocyte diaphragm)|go:"GO:0007391"(dorsal closure)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008258"(head involution)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0022416"(chaeta development)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030424"(axon)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035156"(fusion cell fate specification)|go:"GO:0035220"(wing disc development)|go:"GO:0036059"(nephrocyte diaphragm assembly)|go:"GO:0045177"(apical part of cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034 flybase:FBgn0025865|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030478"(actin cap)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070864"(sperm individualization complex)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR035716|interpro:IPR036028 pubmed:9792678(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:BgdNMn3rvKsUz+8OJRoFTaYeNtE7227 rogid:Ivff7cAgDDrqDMLxqhaF10gjjP47227 intact-crc:2D4935F4E280C691|rigid:EL8A16moBxQ8hD6lWTy1IBUKmA8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O16844 uniprotkb:P91682 intact:EBI-102069|intact:EBI-868718|intact:EBI-1151174|intact:EBI-497208|uniprotkb:A1Z6X4|uniprotkb:B5RIP3|uniprotkb:Q6AWI9|uniprotkb:Q8IH04|ensemblmetazoa:FBpp0088087|ensemblmetazoa:FBpp0307854 intact:EBI-142245|uniprotkb:Q9VPM8|uniprotkb:B7FNK1|ensemblmetazoa:FBpp0077788 psi-mi:cos_drome(display_long)|uniprotkb:cos(gene name)|psi-mi:cos(display_short)|uniprotkb:cos2(gene name synonym)|uniprotkb:costal-2(gene name synonym)|uniprotkb:Kinesin-like protein costal2(gene name synonym)|uniprotkb:CG1708(orf name) psi-mi:smo_drome(display_long)|uniprotkb:smo(gene name)|psi-mi:smo(display_short)|uniprotkb:CG11561(orf name)|uniprotkb:dSMO(gene name synonym)|uniprotkb:SMOH(gene name synonym)|uniprotkb:Smooth(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872114 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477092.1|flybase:FBgn0000352|ensemblmetazoa:FBgn0000352(gene)|ensemblmetazoa:FBtr0089015(transcript)|ensemblmetazoa:FBtr0336916(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005119"(smoothened binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0008017"(microtubule binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-216119|reactome:R-DME-216217|refseq:NP_001260765.1|dip:DIP-22550N refseq:NP_523443.1|flybase:FBgn0003444|dip:DIP-19956N|ensemblmetazoa:FBgn0003444(gene)|ensemblmetazoa:FBtr0078129(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0002385"(mucosal immune response)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005113"(patched binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048099"(anterior/posterior lineage restriction, imaginal disc)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026544|interpro:IPR035683|interpro:IPR036790|interpro:IPR041771|rcsb pdb:2MAH|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-216119|reactome:R-DME-216217|reactome:R-DME-5610787|reactome:R-DME-5620922|reactome:R-DME-5635838 pubmed:14614827(see-also)|pubmed:14636583(see-also)|pubmed:14523402(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6k5Ur6D1FPXovKN/UUjCoqKajQk7227 rogid:B/9O3wxDY6qY2W709uuH3tz1XTY7227 intact-crc:CD6F90694AE293E7|rigid:MLEovjBqI9I/n7xwkXo0D0HYF+0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P23647 uniprotkb:O16844 intact:EBI-165536|ensemblmetazoa:FBpp0074373|uniprotkb:Q26346|uniprotkb:Q26347|uniprotkb:Q27412|uniprotkb:Q9VWR7 intact:EBI-102069|intact:EBI-868718|intact:EBI-1151174|intact:EBI-497208|uniprotkb:A1Z6X4|uniprotkb:B5RIP3|uniprotkb:Q6AWI9|uniprotkb:Q8IH04|ensemblmetazoa:FBpp0088087|ensemblmetazoa:FBpp0307854 psi-mi:fused_drome(display_long)|uniprotkb:fu(gene name)|psi-mi:fu(display_short)|uniprotkb:CG6551(orf name) psi-mi:cos_drome(display_long)|uniprotkb:cos(gene name)|psi-mi:cos(display_short)|uniprotkb:cos2(gene name synonym)|uniprotkb:costal-2(gene name synonym)|uniprotkb:Kinesin-like protein costal2(gene name synonym)|uniprotkb:CG1708(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0001079(gene)|ensemblmetazoa:FBtr0074602(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007228"(positive regulation of hh target transcription factor activity)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007367"(segment polarity determination)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0005119"(smoothened binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6LPH|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-216119|reactome:R-DME-216217|refseq:NP_477499.1|flybase:FBgn0001079|dip:DIP-492N refseq:NP_477092.1|flybase:FBgn0000352|ensemblmetazoa:FBgn0000352(gene)|ensemblmetazoa:FBtr0089015(transcript)|ensemblmetazoa:FBtr0336916(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005119"(smoothened binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0008017"(microtubule binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-216119|reactome:R-DME-216217|refseq:NP_001260765.1|dip:DIP-22550N pubmed:11839821(see-also)|pubmed:9244297(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:5KrFb8xuGHpjwIlFMx4AkeD9/m47227 rogid:6k5Ur6D1FPXovKN/UUjCoqKajQk7227 intact-crc:0AB2D8B4F2591B14|rigid:bJKZP3SMTzOy8HkKRhCzyMFRo9s false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24147 uniprotkb:Q24478 intact:EBI-868853 intact:EBI-868840|intact:EBI-1627969|uniprotkb:A4V2Y3|uniprotkb:Q9VFA1|ensemblmetazoa:FBpp0082580|ensemblmetazoa:FBpp0082581 psi-mi:q24147_drome(display_long)|uniprotkb:Map60(gene name)|psi-mi:Map60(display_short)|uniprotkb:Cp60(gene name synonym)|uniprotkb:CG1825(orf name) psi-mi:cp190_drome(display_long)|uniprotkb:Cp190(gene name)|psi-mi:Cp190(display_short)|uniprotkb:"E(mod)4-1"(gene name synonym)|uniprotkb:CG6384(orf name)|uniprotkb:dMAP190(gene name synonym)|uniprotkb:"Protein enhancer of mod(mdg4)4-1"(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0010342|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0008017"(microtubule binding)|interpro:IPR006578(MADF)|mint:Q24147 refseq:NP_524359.2|refseq:NP_731998.1|flybase:FBgn0000283|ensemblmetazoa:FBgn0000283(gene)|ensemblmetazoa:FBtr0083126(transcript)|ensemblmetazoa:FBtr0083127(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008017"(microtubule binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0035191"(nuclear axial expansion)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0140588"(chromatin looping)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q24478|rcsb pdb:4U77|rcsb pdb:5EUP|rcsb pdb:6ER1 pubmed:8590797(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:0YEuPvKSjHSoA11nDAyszWGy1OM7227 rogid:nfYr0w5JQEwE6/9PftioES7vjCo7227 intact-crc:9F6E23E6FCF39B09|rigid:tdNSVNAAAWeCRSDASq62Mc0bAOs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10040 uniprotkb:P46150 intact:EBI-672928|uniprotkb:Q0KI19|uniprotkb:Q8MSX5|uniprotkb:Q9VC97|ensemblmetazoa:FBpp0083987 intact:EBI-206130|uniprotkb:P91930|uniprotkb:Q24053|uniprotkb:Q24435|uniprotkb:Q9W3B4|uniprotkb:A4V458|uniprotkb:Q7KVS6|uniprotkb:Q7KVS7|uniprotkb:Q9W3B5|uniprotkb:Q9W3B6|uniprotkb:Q9W3B7|ensemblmetazoa:FBpp0089236|ensemblmetazoa:FBpp0300514 psi-mi:crb_drome(display_long)|uniprotkb:95F(gene name synonym)|uniprotkb:crb(gene name)|psi-mi:crb(display_short)|uniprotkb:CG6383(orf name) psi-mi:moeh_drome(display_long)|uniprotkb:Moe(gene name)|psi-mi:Moe(display_short)|uniprotkb:EMR1(gene name synonym)|uniprotkb:CG10701(orf name)|uniprotkb:Moesin(gene name synonym)|uniprotkb:Protein D17(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872130 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036751.1|refseq:NP_524480.2|flybase:FBgn0259685|dip:DIP-40915N|ensemblmetazoa:FBgn0259685(gene)|ensemblmetazoa:FBtr0084603(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003383"(apical constriction)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016332"(establishment or maintenance of polarity of embryonic epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0030507"(spectrin binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0034332"(adherens junction organization)|go:"GO:0035002"(liquid clearance, open tracheal system)|go:"GO:0035003"(subapical complex)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035090"(maintenance of apical/basal cell polarity)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042052"(rhabdomere development)|go:"GO:0045176"(apical protein localization)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0046665"(amnioserosa maintenance)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0060438"(trachea development)|go:"GO:0061024"(membrane organization)|go:"GO:0061336"(cell morphogenesis involved in Malpighian tubule morphogenesis)|go:"GO:0061541"(rhabdomere morphogenesis)|go:"GO:0098813"(nuclear chromosome segregation)|go:"GO:0106036"(assembly of apicomedial cortex actomyosin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4WSI|rcsb pdb:4YL8 refseq:NP_001245584.1|refseq:NP_525082.2|refseq:NP_727290.1|refseq:NP_727291.1|refseq:NP_727292.1|refseq:NP_996387.1|refseq:NP_996388.1|refseq:NP_996389.1|refseq:NP_996390.1|refseq:NP_996391.1|refseq:NP_996392.1|flybase:FBgn0011661|dip:DIP-52150N|ensemblmetazoa:FBgn0011661(gene)|ensemblmetazoa:FBtr0071278(transcript)|ensemblmetazoa:FBtr0308194(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003779"(actin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008017"(microtubule binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016057"(regulation of membrane potential in photoreceptor cell)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016336"(establishment or maintenance of polarity of larval imaginal disc epithelium)|go:"GO:0030029"(actin filament-based process)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0035003"(subapical complex)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0035327"|go:"GO:0042052"(rhabdomere development)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045313"(rhabdomere membrane biogenesis)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|reactome:R-DME-373752 pubmed:12213838(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:eFe13WHwi5bdLUm1xQxhj22j9JU7227 rogid:SOC9aiyQCcmj5WK8Qr3obv9rxz87227 intact-crc:18A9B103B7E4046B|rigid:uWSGIZzKNsLkMXuLWr/XZkjqzng false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8T626 uniprotkb:P10040 intact:EBI-424300|uniprotkb:Q8T627|uniprotkb:Q9W084|ensemblmetazoa:FBpp0072673 intact:EBI-672928|uniprotkb:Q0KI19|uniprotkb:Q8MSX5|uniprotkb:Q9VC97|ensemblmetazoa:FBpp0083987 psi-mi:dlt_drome(display_long)|uniprotkb:Protein vanaso(gene name synonym)|uniprotkb:Codanin 1 homolog(gene name synonym)|uniprotkb:dlt(gene name)|psi-mi:dlt(display_short)|uniprotkb:VA(gene name synonym)|uniprotkb:CG32315(orf name) psi-mi:crb_drome(display_long)|uniprotkb:95F(gene name synonym)|uniprotkb:crb(gene name)|psi-mi:crb(display_short)|uniprotkb:CG6383(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872134 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_728672.1|flybase:FBgn0024510|ensemblmetazoa:FBgn0024510(gene)|ensemblmetazoa:FBtr0072790(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005737"(cytoplasm)|go:"GO:0007560"(imaginal disc morphogenesis)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR028171|interpro:IPR040031|dip:DIP-22407N refseq:NP_001036751.1|refseq:NP_524480.2|flybase:FBgn0259685|dip:DIP-40915N|ensemblmetazoa:FBgn0259685(gene)|ensemblmetazoa:FBtr0084603(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003383"(apical constriction)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016332"(establishment or maintenance of polarity of embryonic epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0030507"(spectrin binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0034332"(adherens junction organization)|go:"GO:0035002"(liquid clearance, open tracheal system)|go:"GO:0035003"(subapical complex)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035090"(maintenance of apical/basal cell polarity)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042052"(rhabdomere development)|go:"GO:0045176"(apical protein localization)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0046665"(amnioserosa maintenance)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0060438"(trachea development)|go:"GO:0061024"(membrane organization)|go:"GO:0061336"(cell morphogenesis involved in Malpighian tubule morphogenesis)|go:"GO:0061541"(rhabdomere morphogenesis)|go:"GO:0098813"(nuclear chromosome segregation)|go:"GO:0106036"(assembly of apicomedial cortex actomyosin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4WSI|rcsb pdb:4YL8 pubmed:10662667(see-also)|pubmed:10102271(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:XbkVY7EHTI+LVCWesMz/abFkq+M7227 rogid:eFe13WHwi5bdLUm1xQxhj22j9JU7227 intact-crc:2670C203EB0887EF|rigid:eeLgfqjSABc7fkT10QdDOIvtXBM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8MQW7 uniprotkb:Q9XYM0 intact:EBI-868875|ensemblmetazoa:FBpp0083850 intact:EBI-99477|uniprotkb:Q53XD2|ensemblmetazoa:FBpp0088181|ensemblmetazoa:FBpp0088182 psi-mi:q8mqw7_drome(display_long)|uniprotkb:mbc(gene name)|psi-mi:mbc(display_short)|uniprotkb:CG10379(orf name) psi-mi:crk_drome(display_long)|uniprotkb:Crk(gene name)|psi-mi:Crk(display_short)|uniprotkb:CG1587(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872138 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0015513|ensemblmetazoa:FBgn0015513(gene)|ensemblmetazoa:FBtr0084459(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007417"(central nervous system development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007523"(larval visceral muscle development)|go:"GO:0016203"(muscle attachment)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0061327"(anterior Malpighian tubule development)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR026791|interpro:IPR027357|interpro:IPR043161|interpro:IPR043162 refseq:NP_651908.1|refseq:NP_726549.1|flybase:FBgn0024811|ensemblmetazoa:FBgn0024811(gene)|ensemblmetazoa:FBtr0089112(transcript)|ensemblmetazoa:FBtr0089113(transcript)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:Q9XYM0|reactome:R-DME-186763|reactome:R-DME-8849471|reactome:R-DME-9027284|reactome:R-DME-912631|dip:DIP-21287N pubmed:10072777(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:WKK1nlVkrBUJBbPvHxb3al9gc+07227 rogid:/aQyKHKPKNANVUGCJwbvoeZrYiI7227 intact-crc:FDF186F7740C9F4D|rigid:HUqQoW4dRumLGFY6SHQ5D/2rcVU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P17917 uniprotkb:O76906 intact:EBI-148806|intact:EBI-1628820|uniprotkb:Q9V909|uniprotkb:Q540V1|ensemblmetazoa:FBpp0085619|ensemblmetazoa:FBpp0089395 intact:EBI-121676|uniprotkb:Q8MX91|uniprotkb:Q8MX92|uniprotkb:Q8MX93|uniprotkb:Q8MX94|uniprotkb:Q8MX95|uniprotkb:Q0KHW5|uniprotkb:Q8MM10|uniprotkb:Q8MM41|uniprotkb:Q8MM71|uniprotkb:Q8MX89|uniprotkb:Q8MX90|uniprotkb:Q9W4V7|ensemblmetazoa:FBpp0070472|ensemblmetazoa:FBpp0070473 psi-mi:pcna_drome(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym)|uniprotkb:Mutagen-sensitive 209 protein(gene name synonym)|uniprotkb:mus209(gene name synonym)|uniprotkb:CG9193(orf name)|uniprotkb:PCNA1(gene name synonym) psi-mi:crm_drome(display_long)|uniprotkb:crm(gene name)|psi-mi:crm(display_short)|uniprotkb:CG2714(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872142 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476905.1|refseq:NP_995904.1|flybase:FBgn0005655|dip:DIP-20560N|reactome:R-DME-5358565|reactome:R-DME-5651801|reactome:R-DME-5655862|reactome:R-DME-5656121|reactome:R-DME-5656169|reactome:R-DME-5696400|reactome:R-DME-6782135|reactome:R-DME-6804114|reactome:R-DME-69091|reactome:R-DME-69166|reactome:R-DME-69183|reactome:R-DME-110320|ensemblmetazoa:FBgn0005655(gene)|ensemblmetazoa:FBtr0086307(transcript)|ensemblmetazoa:FBtr0086308(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0009411"(response to UV)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043626"(PCNA complex)|go:"GO:0072702"(response to methyl methanesulfonate)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:4HK1|reactome:R-DME-110312|reactome:R-DME-110314 ensemblmetazoa:FBgn0000376(gene)|ensemblmetazoa:FBtr0070495(transcript)|ensemblmetazoa:FBtr0070496(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007389"(pattern specification process)|interpro:IPR001005(SANT, DNA-binding)|refseq:NP_477105.2|refseq:NP_726829.1|flybase:FBgn0000376 pubmed:9310333(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:JlorjL2CuAoJHo8z4Cnb16+Muf87227 rogid:K2rwDTYsqYtL9ZC9d0gOimHPwSg7227 intact-crc:40C6DFBC185110BB|rigid:yhINYqW4uG5sRgPGdlwk/UpoMVM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P49021 uniprotkb:O77059 intact:EBI-266295|uniprotkb:O44380|uniprotkb:Q8I037|uniprotkb:Q95U67|uniprotkb:Q9VQR6|uniprotkb:Q9VQR7|intact:EBI-3407510|uniprotkb:M9MRE9|uniprotkb:A4V040|uniprotkb:B7Z007|uniprotkb:B7Z008|uniprotkb:C9QPB7|uniprotkb:Q1WWF5|uniprotkb:Q59E16|intact:EBI-9944820|ensemblmetazoa:FBpp0077256|ensemblmetazoa:FBpp0305454 intact:EBI-94117|uniprotkb:Q9TYA0|ensemblmetazoa:FBpp0083150 psi-mi:tim_drome(display_long)|uniprotkb:tim(gene name)|psi-mi:tim(display_short)|uniprotkb:CG3234(orf name) psi-mi:cry1_drome(display_long)|uniprotkb:cry(gene name)|psi-mi:cry(display_short)|uniprotkb:Blue light photoreceptor(gene name synonym)|uniprotkb:CG3772(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_722914.3|flybase:FBgn0014396|refseq:NP_722912.3|refseq:NP_722913.3|refseq:NP_001014463.2|refseq:NP_001033872.2|refseq:NP_001137780.2|refseq:NP_001137781.2|refseq:NP_001188686.2|dip:DIP-29425N|ensemblmetazoa:FBgn0014396(gene)|ensemblmetazoa:FBtr0077567(transcript)|ensemblmetazoa:FBtr0333256(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003053"(circadian regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007617"(mating behavior)|go:"GO:0007620"(copulation)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009648"(photoperiodism)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0043111"(replication fork arrest)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0046957"(negative phototaxis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048478"(replication fork protection)|go:"GO:0048512"(circadian behavior)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR006906(Timeless protein)|interpro:IPR007725(Timeless C-terminal)|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 refseq:NP_732407.1|flybase:FBgn0025680|ensemblmetazoa:FBgn0025680(gene)|ensemblmetazoa:FBtr0083736(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007602"(phototransduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009588"(UV-A, blue light phototransduction)|go:"GO:0009637"(response to blue light)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0009785"(blue light signaling pathway)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0009882"(blue light photoreceptor activity)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042332"(gravitaxis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048512"(circadian behavior)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050958"(magnetoreception)|go:"GO:0050980"(detection of light stimulus involved in magnetoreception)|go:"GO:0071000"(response to magnetism)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0071949"(FAD binding)|interpro:IPR002081(Cryptochrome/DNA photolyase, class 1)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|rcsb pdb:4GU5|rcsb pdb:4JZY|rcsb pdb:4K03|rcsb pdb:6WTB|reactome:R-DME-432395|reactome:R-DME-432553|reactome:R-DME-538864|dip:DIP-29424N pubmed:10417378(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:wdN/j17nXo6XpfHUGGSo5zYNhog7227 rogid:oK310WTO66wYsiRt4J7d6x1EHYs7227 intact-crc:42AC9A8FB85C5DC5|rigid:5FSW0WSdUm6/Jt3GCymtjEpgxyg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07663 uniprotkb:O77059 intact:EBI-496170|uniprotkb:O17483|uniprotkb:O76882|uniprotkb:O76883|uniprotkb:O76884|uniprotkb:O76885|uniprotkb:Q24446|uniprotkb:Q24447|uniprotkb:Q24448|uniprotkb:Q24449|uniprotkb:Q6PVA3|uniprotkb:Q8MLY0|uniprotkb:Q9GN20|uniprotkb:Q9GN51|uniprotkb:Q9GQH9|uniprotkb:Q9GV48|uniprotkb:Q9GV53|uniprotkb:Q9GV54|uniprotkb:Q9GV55|uniprotkb:Q9W4X0|ensemblmetazoa:FBpp0070455 intact:EBI-94117|uniprotkb:Q9TYA0|ensemblmetazoa:FBpp0083150 psi-mi:per_drome(display_long)|uniprotkb:Protein clock-6(gene name synonym)|uniprotkb:per(gene name)|psi-mi:per(display_short)|uniprotkb:CG2647(orf name) psi-mi:cry1_drome(display_long)|uniprotkb:cry(gene name)|psi-mi:cry(display_short)|uniprotkb:Blue light photoreceptor(gene name synonym)|uniprotkb:CG3772(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525056.2|flybase:FBgn0003068|refseq:NP_001259194.1|dip:DIP-29426N|ensemblmetazoa:FBgn0003068(gene)|ensemblmetazoa:FBtr0070477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001306"(age-dependent response to oxidative stress)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007616"(long-term memory)|go:"GO:0007617"(mating behavior)|go:"GO:0007619"(courtship behavior)|go:"GO:0007620"(copulation)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0044297"(cell body)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0048512"(circadian behavior)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR035965|rcsb pdb:1WA9|rcsb pdb:3GEC|rcsb pdb:3RTY|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432524|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 refseq:NP_732407.1|flybase:FBgn0025680|ensemblmetazoa:FBgn0025680(gene)|ensemblmetazoa:FBtr0083736(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007602"(phototransduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009588"(UV-A, blue light phototransduction)|go:"GO:0009637"(response to blue light)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0009785"(blue light signaling pathway)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0009882"(blue light photoreceptor activity)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042332"(gravitaxis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048512"(circadian behavior)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050958"(magnetoreception)|go:"GO:0050980"(detection of light stimulus involved in magnetoreception)|go:"GO:0071000"(response to magnetism)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0071949"(FAD binding)|interpro:IPR002081(Cryptochrome/DNA photolyase, class 1)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|rcsb pdb:4GU5|rcsb pdb:4JZY|rcsb pdb:4K03|rcsb pdb:6WTB|reactome:R-DME-432395|reactome:R-DME-432553|reactome:R-DME-538864|dip:DIP-29424N pubmed:11448767(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+l/mg+2MJForY5dORYWnWsVAhNI7227 rogid:oK310WTO66wYsiRt4J7d6x1EHYs7227 intact-crc:E61A0204709641B6|rigid:jcB64cmjRNjITq18vVuhxSWNj5E false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P11147 uniprotkb:Q03751 intact:EBI-75181|uniprotkb:Q3KN45|uniprotkb:Q8SXQ4|uniprotkb:Q9VFB0|ensemblmetazoa:FBpp0082514|ensemblmetazoa:FBpp0082515|ensemblmetazoa:FBpp0082516|ensemblmetazoa:FBpp0082517|ensemblmetazoa:FBpp0082518|ensemblmetazoa:FBpp0082519|ensemblmetazoa:FBpp0307982 intact:EBI-604931|uniprotkb:O61664|uniprotkb:O61665|uniprotkb:Q95TD7|uniprotkb:Q9VNV1 psi-mi:hsp7d_drome(display_long)|uniprotkb:Hsc70-4(gene name)|psi-mi:Hsc70-4(display_short)|uniprotkb:Hsc4(gene name synonym)|uniprotkb:CG4264(orf name)|uniprotkb:Heat shock 70 kDa protein 88E(gene name synonym) psi-mi:dnjc5_drome(display_long)|uniprotkb:Csp(gene name)|psi-mi:Csp(display_short)|uniprotkb:Cysteine string protein(gene name synonym)|uniprotkb:CG6395(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524356.1|refseq:NP_731987.1|refseq:NP_731988.1|refseq:NP_731989.1|refseq:NP_788679.1|refseq:NP_788680.1|flybase:FBgn0266599|refseq:NP_001262586.1|dip:DIP-19158N|ensemblmetazoa:FBgn0266599(gene)|ensemblmetazoa:FBtr0083055(transcript)|ensemblmetazoa:FBtr0083056(transcript)|ensemblmetazoa:FBtr0083057(transcript)|ensemblmetazoa:FBtr0083058(transcript)|ensemblmetazoa:FBtr0083059(transcript)|ensemblmetazoa:FBtr0083060(transcript)|ensemblmetazoa:FBtr0337053(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016246"(RNA interference)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0035967"(cellular response to topologically incorrect protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097753"(membrane bending)|go:"GO:0098793"(presynapse)|go:"GO:0106161"(obsolete positive regulation of small RNA loading onto RISC)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11147|reactome:R-DME-3371453|reactome:R-DME-3371497|reactome:R-DME-3371571|reactome:R-DME-450408|reactome:R-DME-6798695|reactome:R-DME-72163|reactome:R-DME-8856828|reactome:R-DME-888590 go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006887"(exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0043195"(terminal bouton)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061177"(type Is terminal bouton)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:1900073"(regulation of neuromuscular synaptic transmission)|go:"GO:1903035"(negative regulation of response to wounding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|reactome:R-DME-6798695|reactome:R-DME-888590|refseq:NP_524213.1|refseq:NP_730713.1|refseq:NP_730714.2|flybase:FBgn0004179|refseq:NP_001287144.1 pubmed:11395008(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:0e7AjwNXSuekfdcT63i3/qeJ5ww7227 rogid:xCilLP0qwRho5gvMdrvW1P1RK2s7227 intact-crc:CEDA9B4095B4493F|rigid:YmseXaWl0T1FjW1yNdtAKvZunr8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P25991 uniprotkb:Q86NL1 intact:EBI-868900|uniprotkb:A0A023GQK0|uniprotkb:Q5BI40|uniprotkb:Q6NKM3|uniprotkb:Q7PLW9|uniprotkb:Q7PLX0|uniprotkb:Q7PLX1|uniprotkb:Q9W5P7|uniprotkb:A8Y5B4|uniprotkb:A8Y5B5|uniprotkb:Q24539|uniprotkb:Q8MZI2|ensemblmetazoa:FBpp0297502 intact:EBI-868890|ensemblmetazoa:FBpp0083075 psi-mi:suf_drome(display_long)|uniprotkb:"su(f)"(gene name)|psi-mi:"su(f)"(display_short)|uniprotkb:CG17170(orf name) psi-mi:q86nl1_drome(display_long)|uniprotkb:CstF64(gene name)|psi-mi:CstF64(display_short)|uniprotkb:CstF-64(gene name synonym)|uniprotkb:CG7697(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872158 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001015241.3|refseq:NP_001104480.2|refseq:NP_001104479.1|flybase:FBgn0003559|dip:DIP-22591N|ensemblmetazoa:FBgn0003559(gene)|ensemblmetazoa:FBtr0306544(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005848"(mRNA cleavage stimulating factor complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:1903220"("positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity")|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR008847(Suppressor of forked)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-72163|reactome:R-DME-72187|reactome:R-DME-73856|reactome:R-DME-77595 flybase:FBgn0027841|ensemblmetazoa:FBgn0027841(gene)|ensemblmetazoa:FBtr0083660(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR025742|interpro:IPR026896|interpro:IPR035979|interpro:IPR038192 pubmed:10606651(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:hfri2YSI44RobrSM58sGOc0Ho107227 rogid:I98mgb0Ky3/9yLfSn7Vmwjubn1Q7227 intact-crc:FEF6890C7993872D|rigid:YhenVwjgpaxCCqWIQiWtHXkrYmk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18475 uniprotkb:P29349 intact:EBI-195402|uniprotkb:A8DY54|uniprotkb:A8DY56|uniprotkb:Q9V4R2|ensemblmetazoa:FBpp0088012 intact:EBI-208539|uniprotkb:Q24032|uniprotkb:Q24033|uniprotkb:Q8I074|uniprotkb:Q8I0H8|uniprotkb:Q8I0S4|uniprotkb:Q8ISD5|uniprotkb:Q8ISD6|uniprotkb:Q9V3H1|uniprotkb:Q9W524 psi-mi:torso_drome(display_long)|uniprotkb:tor(gene name)|psi-mi:tor(display_short)|uniprotkb:CG1389(orf name) psi-mi:csw_drome(display_long)|uniprotkb:csw(gene name)|psi-mi:csw(display_short)|uniprotkb:CG3954(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872162 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097212.2|refseq:NP_476762.1|flybase:FBgn0003733|ensemblmetazoa:FBgn0003733(gene)|ensemblmetazoa:FBtr0088938(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007278"(pole cell fate determination)|go:"GO:0007280"(pole cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0046957"(negative phototaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116 refseq:NP_477130.1|refseq:NP_477131.1|refseq:NP_726793.1|flybase:FBgn0000382|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007362"(terminal region determination)|go:"GO:0007418"(ventral midline development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007498"(mesoderm development)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016311"(dephosphorylation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045314"(regulation of compound eye photoreceptor development)|go:"GO:0045500"(sevenless signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|reactome:R-DME-6798695 pubmed:9885560(see-also)|pubmed:8598287(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xto08nbumwFlew52tyO4IgeMEqs7227 rogid:8cPxz9jsuZeJmMHnTa0xLs5EAT47227 intact-crc:D3DB167C98341861|rigid:pVepQJvcdXf5oFIeo8k1ZzAFVow false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KIF8 uniprotkb:P29349 intact:EBI-868910 intact:EBI-208539|uniprotkb:Q24032|uniprotkb:Q24033|uniprotkb:Q8I074|uniprotkb:Q8I0H8|uniprotkb:Q8I0S4|uniprotkb:Q8ISD5|uniprotkb:Q8ISD6|uniprotkb:Q9V3H1|uniprotkb:Q9W524 psi-mi:q7kif8_drome(display_long)|uniprotkb:msk(gene name)|psi-mi:msk(display_short)|uniprotkb:CG7935(orf name) psi-mi:csw_drome(display_long)|uniprotkb:csw(gene name)|psi-mi:csw(display_short)|uniprotkb:CG3954(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872166 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0026252|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0015030"(Cajal body)|go:"GO:0016203"(muscle attachment)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0030576"(Cajal body organization)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035311"(wing cell fate specification)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045465"(R8 cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048749"(compound eye development)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold) refseq:NP_477130.1|refseq:NP_477131.1|refseq:NP_726793.1|flybase:FBgn0000382|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007362"(terminal region determination)|go:"GO:0007418"(ventral midline development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007498"(mesoderm development)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016311"(dephosphorylation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045314"(regulation of compound eye photoreceptor development)|go:"GO:0045500"(sevenless signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|reactome:R-DME-6798695 pubmed:11262240(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:LyYWvxv5lrIKAyUcBdCYuv0gajw7227 rogid:8cPxz9jsuZeJmMHnTa0xLs5EAT47227 intact-crc:E4C14B58978674E0|rigid:MvyTZ+BRN1N8AyCSIl7zZZUXq2o false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q08012 uniprotkb:P29349 intact:EBI-161391|uniprotkb:Q0E989|uniprotkb:Q9V6Q5|uniprotkb:A4UZF9|ensemblmetazoa:FBpp0086813|ensemblmetazoa:FBpp0086814|ensemblmetazoa:FBpp0086815|ensemblmetazoa:FBpp0086816|ensemblmetazoa:FBpp0086817 intact:EBI-208539|uniprotkb:Q24032|uniprotkb:Q24033|uniprotkb:Q8I074|uniprotkb:Q8I0H8|uniprotkb:Q8I0S4|uniprotkb:Q8ISD5|uniprotkb:Q8ISD6|uniprotkb:Q9V3H1|uniprotkb:Q9W524 psi-mi:grap_drome(display_long)|uniprotkb:drk(gene name)|psi-mi:drk(display_short)|uniprotkb:"E(sev)2B"(gene name synonym)|uniprotkb:Downstream of receptor kinase(gene name synonym)|uniprotkb:Grb2(gene name synonym)|uniprotkb:Protein enhancer of sevenless 2B(gene name synonym)|uniprotkb:CG6033(orf name) psi-mi:csw_drome(display_long)|uniprotkb:csw(gene name)|psi-mi:csw(display_short)|uniprotkb:CG3954(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872170 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476858.1|refseq:NP_725302.1|refseq:NP_725303.1|refseq:NP_725304.1|refseq:NP_725306.1|flybase:FBgn0004638|ensemblmetazoa:FBgn0004638(gene)|ensemblmetazoa:FBtr0087694(transcript)|ensemblmetazoa:FBtr0087695(transcript)|ensemblmetazoa:FBtr0087696(transcript)|ensemblmetazoa:FBtr0087697(transcript)|ensemblmetazoa:FBtr0087698(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005118"(sevenless binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007614"(short-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR030219|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2A36|go:"GO:0008306"(associative learning)|rcsb pdb:2A37|rcsb pdb:2AZS|rcsb pdb:2AZV|reactome:R-DME-109704|reactome:R-DME-112412|reactome:R-DME-1250347|reactome:R-DME-1257604|reactome:R-DME-1295596|reactome:R-DME-1433557|reactome:R-DME-1433559|reactome:R-DME-167044|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-1963642|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2428933|reactome:R-DME-2730905|reactome:R-DME-2871796|reactome:R-DME-2871809|reactome:R-DME-375165|reactome:R-DME-5654688|go:"GO:0008355"(olfactory learning)|reactome:R-DME-5654689|reactome:R-DME-5654693|reactome:R-DME-5654695|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654710|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5654720|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5673001|reactome:R-DME-6811558|reactome:R-DME-74749|reactome:R-DME-74751|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-9027284|reactome:R-DME-912631|reactome:R-DME-9607240|reactome:R-DME-983695|reactome:R-DME-5654733|dip:DIP-21223N refseq:NP_477130.1|refseq:NP_477131.1|refseq:NP_726793.1|flybase:FBgn0000382|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007362"(terminal region determination)|go:"GO:0007418"(ventral midline development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007498"(mesoderm development)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016311"(dephosphorylation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045314"(regulation of compound eye photoreceptor development)|go:"GO:0045500"(sevenless signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|reactome:R-DME-6798695 pubmed:9885560(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:GNPfKX2LH0HRXEW4ASFDTrXN3VY7227 rogid:8cPxz9jsuZeJmMHnTa0xLs5EAT47227 intact-crc:6824AAB2C2B062E6|rigid:AGV+nYUuXxkrya6VoYNAKqYnpOQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VZZ9 uniprotkb:P29349 intact:EBI-104022|intact:EBI-868924|uniprotkb:Q24452|uniprotkb:Q9W000|ensemblmetazoa:FBpp0072803 intact:EBI-208539|uniprotkb:Q24032|uniprotkb:Q24033|uniprotkb:Q8I074|uniprotkb:Q8I0H8|uniprotkb:Q8I0S4|uniprotkb:Q8ISD5|uniprotkb:Q8ISD6|uniprotkb:Q9V3H1|uniprotkb:Q9W524 psi-mi:dos_drome(display_long)|uniprotkb:dos(gene name)|psi-mi:dos(display_short)|uniprotkb:CG1044(orf name) psi-mi:csw_drome(display_long)|uniprotkb:csw(gene name)|psi-mi:csw(display_short)|uniprotkb:CG3954(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872174 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523890.2|refseq:NP_728757.1|flybase:FBgn0016794|ensemblmetazoa:FBtr0072926(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046578"(regulation of Ras protein signal transduction)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-DME-109704|reactome:R-DME-1257604|reactome:R-DME-180292|reactome:R-DME-1963642|reactome:R-DME-2730905|reactome:R-DME-5654689|reactome:R-DME-5654695|reactome:R-DME-5654710|ensemblmetazoa:FBgn0016794(gene)|reactome:R-DME-6811558|reactome:R-DME-9027276|reactome:R-DME-5654720 refseq:NP_477130.1|refseq:NP_477131.1|refseq:NP_726793.1|flybase:FBgn0000382|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007362"(terminal region determination)|go:"GO:0007418"(ventral midline development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007498"(mesoderm development)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016311"(dephosphorylation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045314"(regulation of compound eye photoreceptor development)|go:"GO:0045500"(sevenless signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|reactome:R-DME-6798695 pubmed:8681384(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8+7DM2mtq2Y/RMZxXwE+oyjrT247227 rogid:8cPxz9jsuZeJmMHnTa0xLs5EAT47227 intact-crc:1A98DF1BF8197A1B|rigid:4Kmg/zIEWnLzBCS2tBA1rtfqYwk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P48148 uniprotkb:P25157 intact:EBI-87246|uniprotkb:Q0E958|uniprotkb:Q9V3J0|ensemblmetazoa:FBpp0086353|ensemblmetazoa:FBpp0086354|ensemblmetazoa:FBpp0086355|ensemblmetazoa:FBpp0086356|ensemblmetazoa:FBpp0089129|ensemblmetazoa:FBpp0089130|uniprotkb:A4UZI6 intact:EBI-485522|uniprotkb:Q7PL79|uniprotkb:Q9U3X3|ensemblmetazoa:FBpp0110418|ensemblmetazoa:FBpp0306274 psi-mi:rho1_drome(display_long)|uniprotkb:Rho1(gene name)|psi-mi:Rho1(display_short)|uniprotkb:CG8416(orf name) psi-mi:gnal_drome(display_long)|uniprotkb:cta(gene name)|psi-mi:cta(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CG17678(orf name)|uniprotkb:Protein concertina(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872178 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0014020(gene)|ensemblmetazoa:FBtr0087211(transcript)|ensemblmetazoa:FBtr0087212(transcript)|ensemblmetazoa:FBtr0087213(transcript)|ensemblmetazoa:FBtr0087214(transcript)|ensemblmetazoa:FBtr0087216(transcript)|ensemblmetazoa:FBtr0087217(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007349"(cellularization)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007374"(posterior midgut invagination)|go:"GO:0007377"(germ-band extension)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0005737"(cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0070451"(cell hair)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0110020"(regulation of actomyosin structure organization)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-193634|reactome:R-DME-198203|reactome:R-DME-2173791|reactome:R-DME-350368|reactome:R-DME-350407|reactome:R-DME-350480|reactome:R-DME-392451|reactome:R-DME-3928662|reactome:R-DME-3928663|reactome:R-DME-4086400|interpro:IPR001806(Ras GTPase)|reactome:R-DME-416482|reactome:R-DME-416572|reactome:R-DME-4420097|reactome:R-DME-450728|reactome:R-DME-5625740|reactome:R-DME-5627117|reactome:R-DME-5663220|reactome:R-DME-5666185|reactome:R-DME-5689896|reactome:R-DME-6785631|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-8980692|reactome:R-DME-9013405|reactome:R-DME-9035034|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007601"(visual perception)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035006"(melanization defense response)|go:"GO:0035099"(hemocyte migration)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035298"(regulation of Malpighian tubule size)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0042060"(wound healing)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045179"(apical cortex)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046663"(dorsal closure, leading edge cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0035149"(lumen formation, open tracheal system)|refseq:NP_477098.1|refseq:NP_599135.1|refseq:NP_599136.1|refseq:NP_725524.1|refseq:NP_995849.1|refseq:NP_995850.1|flybase:FBgn0014020|dip:DIP-22676N refseq:NP_001036421.1|flybase:FBgn0000384|ensemblmetazoa:FBtr0111126(transcript)|ensemblmetazoa:FBtr0334157(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003380"(establishment or maintenance of cytoskeleton polarity involved in gastrulation)|go:"GO:0003384"(apical constriction involved in gastrulation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0031526"(brush border membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031752"(D5 dopamine receptor binding)|go:"GO:0043519"(regulation of myosin II filament organization)|ensemblmetazoa:FBgn0000384(gene)|interpro:IPR027417|go:"GO:0046872"(metal ion binding)|go:"GO:0048383"(mesectoderm development)|reactome:R-DME-193648|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0070252"(actin-mediated cell contraction)|interpro:IPR000469(G-protein alpha subunit, group 12)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|reactome:R-DME-416482|interpro:IPR011025(G protein alpha subunit, helical insertion)|reactome:R-DME-428930|reactome:R-DME-9013148|reactome:R-DME-9013149|refseq:NP_001260696.1 pubmed:10556060(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:DbVx4weiFRCcGfqdsUQWqWQc0Q47227 rogid:F/DIjv15FFJ6EdgqGjzdzYOXKac7227 intact-crc:EA9A747E274C0398|rigid:NdVy91L3PA/Vby/GlPgvFWUL090 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40795 uniprotkb:P25157 intact:EBI-183027|uniprotkb:Q9VR71|ensemblmetazoa:FBpp0077034|ensemblmetazoa:FBpp0099983|ensemblmetazoa:FBpp0305381|ensemblmetazoa:FBpp0305382|ensemblmetazoa:FBpp0305383|ensemblmetazoa:FBpp0305384 intact:EBI-485522|uniprotkb:Q7PL79|uniprotkb:Q9U3X3|ensemblmetazoa:FBpp0110418|ensemblmetazoa:FBpp0306274 psi-mi:fog_drome(display_long)|uniprotkb:fog(gene name)|psi-mi:fog(display_short)|uniprotkb:CG9559(orf name) psi-mi:gnal_drome(display_long)|uniprotkb:cta(gene name)|psi-mi:cta(display_short)|uniprotkb:CTR(gene name synonym)|uniprotkb:CG17678(orf name)|uniprotkb:Protein concertina(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872182 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033860.1|refseq:NP_523438.1|flybase:FBgn0000719|refseq:NP_001259781.1|refseq:NP_001259782.1|refseq:NP_001259783.1|refseq:NP_001259784.1|ensemblmetazoa:FBgn0000719(gene)|ensemblmetazoa:FBtr0077342(transcript)|ensemblmetazoa:FBtr0100538(transcript)|ensemblmetazoa:FBtr0333179(transcript)|ensemblmetazoa:FBtr0333180(transcript)|ensemblmetazoa:FBtr0333181(transcript)|ensemblmetazoa:FBtr0333182(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003383"(apical constriction)|go:"GO:0003384"(apical constriction involved in gastrulation)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007374"(posterior midgut invagination)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0021782"(glial cell development)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048383"(mesectoderm development)|go:"GO:0060662"(salivary gland cavitation)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0110072"(apical constriction involved in ventral furrow formation)|interpro:IPR031761 refseq:NP_001036421.1|flybase:FBgn0000384|ensemblmetazoa:FBtr0111126(transcript)|ensemblmetazoa:FBtr0334157(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003380"(establishment or maintenance of cytoskeleton polarity involved in gastrulation)|go:"GO:0003384"(apical constriction involved in gastrulation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0031526"(brush border membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031752"(D5 dopamine receptor binding)|go:"GO:0043519"(regulation of myosin II filament organization)|ensemblmetazoa:FBgn0000384(gene)|interpro:IPR027417|go:"GO:0046872"(metal ion binding)|go:"GO:0048383"(mesectoderm development)|reactome:R-DME-193648|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0070252"(actin-mediated cell contraction)|interpro:IPR000469(G-protein alpha subunit, group 12)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|reactome:R-DME-416482|interpro:IPR011025(G protein alpha subunit, helical insertion)|reactome:R-DME-428930|reactome:R-DME-9013148|reactome:R-DME-9013149|refseq:NP_001260696.1 pubmed:8137424(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:YfK/3zKk38FbZ7Vup6Qv0Gkysek7227 rogid:F/DIjv15FFJ6EdgqGjzdzYOXKac7227 intact-crc:CDEE9B3802D9A23A|rigid:OmUIV/vDFFtdsXKr8HI2jpP4rEc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42282 uniprotkb:O46036 intact:EBI-77008|uniprotkb:A4V3Q3|uniprotkb:Q0KHY0|uniprotkb:Q1LZ43|uniprotkb:Q24313|uniprotkb:Q9V9V2|ensemblmetazoa:FBpp0085186|ensemblmetazoa:FBpp0085188|ensemblmetazoa:FBpp0085190|ensemblmetazoa:FBpp0292319 intact:EBI-159330|uniprotkb:O61283|uniprotkb:Q59DX5|ensemblmetazoa:FBpp0099514|uniprotkb:Q95SQ8|uniprotkb:Q9VG02 psi-mi:ttka_drome(display_long)|uniprotkb:ttk(gene name)|psi-mi:ttk(display_short)|uniprotkb:FTZ-F2(gene name synonym)|uniprotkb:CG1856(orf name)|uniprotkb:Tramtrack p88(gene name synonym)|uniprotkb:Repressor protein fushi tarazu(gene name synonym) psi-mi:ctbp_drome(display_long)|uniprotkb:CtBP(gene name)|psi-mi:CtBP(display_short)|uniprotkb:CG7583(orf name)|uniprotkb:dCtBP(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872186 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189329.1|refseq:NP_733443.1|refseq:NP_733444.1|refseq:NP_733445.1|flybase:FBgn0003870|ensemblmetazoa:FBgn0003870(gene)|ensemblmetazoa:FBtr0085825(transcript)|ensemblmetazoa:FBtr0085827(transcript)|ensemblmetazoa:FBtr0085829(transcript)|ensemblmetazoa:FBtr0303227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031208"(POZ domain binding)|go:"GO:0035001"(dorsal trunk growth, open tracheal system)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035151"(regulation of tube size, open tracheal system)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042682"(regulation of compound eye cone cell fate specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045677"(negative regulation of R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048053"(R1/R6 development)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048750"(compound eye corneal lens morphogenesis)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 refseq:NP_001014617.1|refseq:NP_524336.2|refseq:NP_731762.1|refseq:NP_731763.1|refseq:NP_731764.1|flybase:FBgn0020496|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0022416"(chaeta development)|go:"GO:0031010"(ISWI-type complex)|go:"GO:0035220"(wing disc development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051287"(NAD binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:O46036|reactome:R-DME-3769402|go:"GO:0008134"(transcription factor binding)|ensemblmetazoa:FBgn0020496(gene)|ensemblmetazoa:FBtr0100161(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-DME-3899300|reactome:R-DME-4641265|refseq:NP_001262520.1|dip:DIP-17268N pubmed:10978285(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:k0MeF2/ch3ddqz7uLHjP8aeJwoI7227 rogid:hbMeldNlirFwVr+5QX9bGiPqZ1w7227 intact-crc:3B8860ADD5763330|rigid:+VsipO1CEa9Yi6bTlAxdEtb0JFo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08044 uniprotkb:O46036 intact:EBI-152305|uniprotkb:Q9V3D3|ensemblmetazoa:FBpp0080298 intact:EBI-159330|uniprotkb:O61283|uniprotkb:Q59DX5|ensemblmetazoa:FBpp0099514|uniprotkb:Q95SQ8|uniprotkb:Q9VG02 psi-mi:snai_drome(display_long)|uniprotkb:sna(gene name)|psi-mi:sna(display_short)|uniprotkb:CG3956(orf name) psi-mi:ctbp_drome(display_long)|uniprotkb:CtBP(gene name)|psi-mi:CtBP(display_short)|uniprotkb:CG7583(orf name)|uniprotkb:dCtBP(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872190 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476732.1|flybase:FBgn0003448|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P08044|ensemblmetazoa:FBgn0003448(gene)|ensemblmetazoa:FBtr0080739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007417"(central nervous system development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0010004"(gastrulation involving germ band extension)|dip:DIP-21498N refseq:NP_001014617.1|refseq:NP_524336.2|refseq:NP_731762.1|refseq:NP_731763.1|refseq:NP_731764.1|flybase:FBgn0020496|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0022416"(chaeta development)|go:"GO:0031010"(ISWI-type complex)|go:"GO:0035220"(wing disc development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051287"(NAD binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:O46036|reactome:R-DME-3769402|go:"GO:0008134"(transcription factor binding)|ensemblmetazoa:FBgn0020496(gene)|ensemblmetazoa:FBtr0100161(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-DME-3899300|reactome:R-DME-4641265|refseq:NP_001262520.1|dip:DIP-17268N pubmed:9843507(see-also)|pubmed:11731456(see-also)|pubmed:9525852(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:HFtckXPHuhGM8O7Wdy/sQ2fX7AY7227 rogid:hbMeldNlirFwVr+5QX9bGiPqZ1w7227 intact-crc:041E357234A0CD46|rigid:jmhJMFnkEfbAFH4k1XQ/fzVm1B0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07247 uniprotkb:O46036 intact:EBI-672843|uniprotkb:Q8SYW3|uniprotkb:Q9W0V9|ensemblmetazoa:FBpp0072351|ensemblmetazoa:FBpp0305365 intact:EBI-159330|uniprotkb:O61283|uniprotkb:Q59DX5|ensemblmetazoa:FBpp0099514|uniprotkb:Q95SQ8|uniprotkb:Q9VG02 psi-mi:krup_drome(display_long)|uniprotkb:Kr(gene name)|psi-mi:Kr(display_short)|uniprotkb:CG3340(orf name) psi-mi:ctbp_drome(display_long)|uniprotkb:CtBP(gene name)|psi-mi:CtBP(display_short)|uniprotkb:CG7583(orf name)|uniprotkb:dCtBP(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872194 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523867.1|flybase:FBgn0001325|refseq:NP_001261181.1|ensemblmetazoa:FBgn0001325(gene)|ensemblmetazoa:FBtr0072449(transcript)|ensemblmetazoa:FBtr0333162(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007517"(muscle organ development)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061332"(Malpighian tubule bud morphogenesis)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR031243|interpro:IPR036236 refseq:NP_001014617.1|refseq:NP_524336.2|refseq:NP_731762.1|refseq:NP_731763.1|refseq:NP_731764.1|flybase:FBgn0020496|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0022416"(chaeta development)|go:"GO:0031010"(ISWI-type complex)|go:"GO:0035220"(wing disc development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051287"(NAD binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:O46036|reactome:R-DME-3769402|go:"GO:0008134"(transcription factor binding)|ensemblmetazoa:FBgn0020496(gene)|ensemblmetazoa:FBtr0100161(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-DME-3899300|reactome:R-DME-4641265|refseq:NP_001262520.1|dip:DIP-17268N pubmed:9843507(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:r0X90GV+LseJkjX0mKqmA6xjcns7227 rogid:hbMeldNlirFwVr+5QX9bGiPqZ1w7227 intact-crc:40B8BDACE632BB83|rigid:4j7Yqent91PSU6MhYdnkvluhTa0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10734 uniprotkb:O46036 intact:EBI-170297|intact:EBI-1630197|uniprotkb:Q540X6|uniprotkb:Q9VPC6|ensemblmetazoa:FBpp0077941 intact:EBI-159330|uniprotkb:O61283|uniprotkb:Q59DX5|ensemblmetazoa:FBpp0099514|uniprotkb:Q95SQ8|uniprotkb:Q9VG02 psi-mi:knir_drome(display_long)|uniprotkb:kni(gene name)|psi-mi:kni(display_short)|uniprotkb:NR0A1(gene name synonym)|uniprotkb:CG4717(orf name)|uniprotkb:Nuclear receptor subfamily 0 group A member 1(gene name synonym) psi-mi:ctbp_drome(display_long)|uniprotkb:CtBP(gene name)|psi-mi:CtBP(display_short)|uniprotkb:CG7583(orf name)|uniprotkb:dCtBP(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872198 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524187.1|flybase:FBgn0001320|ensemblmetazoa:FBgn0001320(gene)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|ensemblmetazoa:FBtr0078283(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0008270"(zinc ion binding)|dip:DIP-17716N refseq:NP_001014617.1|refseq:NP_524336.2|refseq:NP_731762.1|refseq:NP_731763.1|refseq:NP_731764.1|flybase:FBgn0020496|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0022416"(chaeta development)|go:"GO:0031010"(ISWI-type complex)|go:"GO:0035220"(wing disc development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051287"(NAD binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:O46036|reactome:R-DME-3769402|go:"GO:0008134"(transcription factor binding)|ensemblmetazoa:FBgn0020496(gene)|ensemblmetazoa:FBtr0100161(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-DME-3899300|reactome:R-DME-4641265|refseq:NP_001262520.1|dip:DIP-17268N pubmed:9843507(see-also)|pubmed:10982842(see-also)|pubmed:9525852(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:zPloouLNEALRKuLvtZc0jT4RZu07227 rogid:hbMeldNlirFwVr+5QX9bGiPqZ1w7227 intact-crc:B75A3070F8F1D889|rigid:bmTJwkOcBe5m2+1+Q915b/0r1L0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q02308 uniprotkb:O46036 intact:EBI-222848|uniprotkb:Q9VDK0|uniprotkb:Q9VDK1|uniprotkb:A4V358|uniprotkb:A4V359|uniprotkb:Q6AWM8|uniprotkb:Q960W5|ensemblmetazoa:FBpp0083322|ensemblmetazoa:FBpp0083324 intact:EBI-159330|uniprotkb:O61283|uniprotkb:Q59DX5|ensemblmetazoa:FBpp0099514|uniprotkb:Q95SQ8|uniprotkb:Q9VG02 psi-mi:hles_drome(display_long)|uniprotkb:H(gene name)|psi-mi:H(display_short)|uniprotkb:CG5460(orf name) psi-mi:ctbp_drome(display_long)|uniprotkb:CtBP(gene name)|psi-mi:CtBP(display_short)|uniprotkb:CG7583(orf name)|uniprotkb:dCtBP(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872202 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524418.2|refseq:NP_732533.1|refseq:NP_732534.1|refseq:NP_732535.1|flybase:FBgn0001169|dip:DIP-39152N|ensemblmetazoa:FBgn0001169(gene)|ensemblmetazoa:FBtr0083914(transcript)|ensemblmetazoa:FBtr0083916(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0008052"(sensory organ boundary specification)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|rcsb pdb:5E24 refseq:NP_001014617.1|refseq:NP_524336.2|refseq:NP_731762.1|refseq:NP_731763.1|refseq:NP_731764.1|flybase:FBgn0020496|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0022416"(chaeta development)|go:"GO:0031010"(ISWI-type complex)|go:"GO:0035220"(wing disc development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051287"(NAD binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:O46036|reactome:R-DME-3769402|go:"GO:0008134"(transcription factor binding)|ensemblmetazoa:FBgn0020496(gene)|ensemblmetazoa:FBtr0100161(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-DME-3899300|reactome:R-DME-4641265|refseq:NP_001262520.1|dip:DIP-17268N pubmed:12154126(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:TM6PF6mRjXrOiWFNPSPfb6oLYhg7227 rogid:hbMeldNlirFwVr+5QX9bGiPqZ1w7227 intact-crc:2D03ADED7DC034CC|rigid:+YSJy13XMxtk+M7KgrNgYUYgtPM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P14003 uniprotkb:O46036 intact:EBI-123011|intact:EBI-1639662|uniprotkb:A4V1N7|uniprotkb:Q95NH3|uniprotkb:Q95NU9|uniprotkb:Q9VSN8|ensemblmetazoa:FBpp0076296|ensemblmetazoa:FBpp0099504 intact:EBI-159330|uniprotkb:O61283|uniprotkb:Q59DX5|ensemblmetazoa:FBpp0099514|uniprotkb:Q95SQ8|uniprotkb:Q9VG02 psi-mi:hair_drome(display_long)|uniprotkb:CG6494(orf name)|uniprotkb:h(gene name)|psi-mi:h(display_short) psi-mi:ctbp_drome(display_long)|uniprotkb:CtBP(gene name)|psi-mi:CtBP(display_short)|uniprotkb:CG7583(orf name)|uniprotkb:dCtBP(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872206 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014577.1|refseq:NP_523977.2|flybase:FBgn0001168|ensemblmetazoa:FBgn0001168(gene)|ensemblmetazoa:FBtr0076569(transcript)|ensemblmetazoa:FBtr0100153(transcript)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0035290"(trunk segmentation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061024"(membrane organization)|go:"GO:0070888"(E-box binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P14003|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|dip:DIP-637N refseq:NP_001014617.1|refseq:NP_524336.2|refseq:NP_731762.1|refseq:NP_731763.1|refseq:NP_731764.1|flybase:FBgn0020496|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0022416"(chaeta development)|go:"GO:0031010"(ISWI-type complex)|go:"GO:0035220"(wing disc development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051287"(NAD binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:O46036|reactome:R-DME-3769402|go:"GO:0008134"(transcription factor binding)|ensemblmetazoa:FBgn0020496(gene)|ensemblmetazoa:FBtr0100161(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-DME-3899300|reactome:R-DME-4641265|refseq:NP_001262520.1|dip:DIP-17268N pubmed:9843507(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:bO023bTsk72HhqvmgSjLEIotrDw7227 rogid:hbMeldNlirFwVr+5QX9bGiPqZ1w7227 intact-crc:6291F0CBEFB0DC30|rigid:6SxefJVI+l+gOYH86/l/XVmVe/0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40688 uniprotkb:Q24117 intact:EBI-173220|uniprotkb:Q9W400|ensemblmetazoa:FBpp0070884 intact:EBI-156442|uniprotkb:A4V3Y5|uniprotkb:Q9V3Y6|ensemblmetazoa:FBpp0070672|ensemblmetazoa:FBpp0070674|ensemblmetazoa:FBpp0070675|ensemblmetazoa:FBpp0297908 psi-mi:swa_drome(display_long)|uniprotkb:swa(gene name)|psi-mi:swa(display_short)|uniprotkb:CG3429(orf name) psi-mi:dyl1_drome(display_long)|uniprotkb:ctp(gene name)|psi-mi:ctp(display_short)|uniprotkb:Cdlc1(gene name synonym)|uniprotkb:ddlc1(gene name synonym)|uniprotkb:CG6998(orf name)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Cut up protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872210 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511060.2|flybase:FBgn0003655|dip:DIP-17669N|ensemblmetazoa:FBgn0003655(gene)|ensemblmetazoa:FBtr0070922(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0045450"(bicoid mRNA localization)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|rcsb pdb:3BRL|rcsb pdb:3E2B|rcsb pdb:6XOR refseq:NP_001245530.1|refseq:NP_525075.1|refseq:NP_726942.1|refseq:NP_726943.1|flybase:FBgn0011760|dip:DIP-17520N|ensemblmetazoa:FBgn0011760(gene)|ensemblmetazoa:FBtr0070704(transcript)|ensemblmetazoa:FBtr0070706(transcript)|ensemblmetazoa:FBtr0070707(transcript)|ensemblmetazoa:FBtr0307065(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006914"(autophagy)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030286"(dynein complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0035220"(wing disc development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1904801"(positive regulation of neuron remodeling)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|rcsb pdb:1RHW|rcsb pdb:2P2T|rcsb pdb:2PG1|rcsb pdb:3BRI|rcsb pdb:3BRL|rcsb pdb:3DVH|rcsb pdb:3DVP|rcsb pdb:3DVT|rcsb pdb:3E2B|rcsb pdb:3FM7|rcsb pdb:3GLW|rcsb pdb:4QH7|rcsb pdb:4QH8|rcsb pdb:5E0L|rcsb pdb:5E0M|rcsb pdb:7K3J|rcsb pdb:7K3K|rcsb pdb:7K3L|reactome:R-DME-1632852|reactome:R-DME-3371497|reactome:R-DME-5620924|reactome:R-DME-6798695|reactome:R-DME-6807878|reactome:R-DME-6811436|reactome:R-DME-9646399 pubmed:10783235(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:TScOq/uoPMn/KJZGTWld7vUt7PY7227 rogid:6vmsGSXptNwMEkZ3YJ6bXYMuicM7227 intact-crc:7067659638E06C4B|rigid:Dp4xy8wFIySEHJkcSzscKOWgFd8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24117 uniprotkb:Q24117 intact:EBI-156442|uniprotkb:A4V3Y5|uniprotkb:Q9V3Y6|ensemblmetazoa:FBpp0070672|ensemblmetazoa:FBpp0070674|ensemblmetazoa:FBpp0070675|ensemblmetazoa:FBpp0297908 intact:EBI-156442|uniprotkb:A4V3Y5|uniprotkb:Q9V3Y6|ensemblmetazoa:FBpp0070672|ensemblmetazoa:FBpp0070674|ensemblmetazoa:FBpp0070675|ensemblmetazoa:FBpp0297908 psi-mi:dyl1_drome(display_long)|uniprotkb:ctp(gene name)|psi-mi:ctp(display_short)|uniprotkb:Cdlc1(gene name synonym)|uniprotkb:ddlc1(gene name synonym)|uniprotkb:CG6998(orf name)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Cut up protein(gene name synonym) psi-mi:dyl1_drome(display_long)|uniprotkb:ctp(gene name)|psi-mi:ctp(display_short)|uniprotkb:Cdlc1(gene name synonym)|uniprotkb:ddlc1(gene name synonym)|uniprotkb:CG6998(orf name)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Cut up protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872214 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245530.1|refseq:NP_525075.1|refseq:NP_726942.1|refseq:NP_726943.1|flybase:FBgn0011760|dip:DIP-17520N|ensemblmetazoa:FBgn0011760(gene)|ensemblmetazoa:FBtr0070704(transcript)|ensemblmetazoa:FBtr0070706(transcript)|ensemblmetazoa:FBtr0070707(transcript)|ensemblmetazoa:FBtr0307065(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006914"(autophagy)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030286"(dynein complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0035220"(wing disc development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1904801"(positive regulation of neuron remodeling)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|rcsb pdb:1RHW|rcsb pdb:2P2T|rcsb pdb:2PG1|rcsb pdb:3BRI|rcsb pdb:3BRL|rcsb pdb:3DVH|rcsb pdb:3DVP|rcsb pdb:3DVT|rcsb pdb:3E2B|rcsb pdb:3FM7|rcsb pdb:3GLW|rcsb pdb:4QH7|rcsb pdb:4QH8|rcsb pdb:5E0L|rcsb pdb:5E0M|rcsb pdb:7K3J|rcsb pdb:7K3K|rcsb pdb:7K3L|reactome:R-DME-1632852|reactome:R-DME-3371497|reactome:R-DME-5620924|reactome:R-DME-6798695|reactome:R-DME-6807878|reactome:R-DME-6811436|reactome:R-DME-9646399 refseq:NP_001245530.1|refseq:NP_525075.1|refseq:NP_726942.1|refseq:NP_726943.1|flybase:FBgn0011760|dip:DIP-17520N|ensemblmetazoa:FBgn0011760(gene)|ensemblmetazoa:FBtr0070704(transcript)|ensemblmetazoa:FBtr0070706(transcript)|ensemblmetazoa:FBtr0070707(transcript)|ensemblmetazoa:FBtr0307065(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006914"(autophagy)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007291"(sperm individualization)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030286"(dynein complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0035220"(wing disc development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1904801"(positive regulation of neuron remodeling)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|rcsb pdb:1RHW|rcsb pdb:2P2T|rcsb pdb:2PG1|rcsb pdb:3BRI|rcsb pdb:3BRL|rcsb pdb:3DVH|rcsb pdb:3DVP|rcsb pdb:3DVT|rcsb pdb:3E2B|rcsb pdb:3FM7|rcsb pdb:3GLW|rcsb pdb:4QH7|rcsb pdb:4QH8|rcsb pdb:5E0L|rcsb pdb:5E0M|rcsb pdb:7K3J|rcsb pdb:7K3K|rcsb pdb:7K3L|reactome:R-DME-1632852|reactome:R-DME-3371497|reactome:R-DME-5620924|reactome:R-DME-6798695|reactome:R-DME-6807878|reactome:R-DME-6811436|reactome:R-DME-9646399 pubmed:11327818(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6vmsGSXptNwMEkZ3YJ6bXYMuicM7227 rogid:6vmsGSXptNwMEkZ3YJ6bXYMuicM7227 intact-crc:B3B9106F0C6E3B23|rigid:5CnsC1zvy3JQ5zLJjtQdo11dc0Q false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VMA3 uniprotkb:P25724 intact:EBI-95398|uniprotkb:O02432|intact:EBI-3427114|ensemblmetazoa:FBpp0288761|ensemblmetazoa:FBpp0312102 intact:EBI-106556|uniprotkb:Q9VDZ6|ensemblmetazoa:FBpp0083146 psi-mi:cup_drome(display_long)|uniprotkb:cup(gene name)|psi-mi:cup(display_short)|uniprotkb:"fs(2)cup"(gene name synonym)|uniprotkb:Oskar ribonucleoprotein complex 147 kDa subunit(gene name synonym)|uniprotkb:CG11181(orf name) psi-mi:nanos_drome(display_long)|uniprotkb:nos(gene name)|psi-mi:nos(display_short)|uniprotkb:CG5637(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872218 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001285687.1|refseq:NP_523493.3|flybase:FBgn0000392|ensemblmetazoa:FBgn0000392(gene)|ensemblmetazoa:FBtr0290322(transcript)|ensemblmetazoa:FBtr0346452(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007319"(negative regulation of oskar mRNA translation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030715"(oocyte growth in germarium-derived egg chamber)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0043195"(terminal bouton)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048477"(oogenesis)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:1905536"(negative regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR018862|rcsb pdb:4AXG|dip:DIP-17920N refseq:NP_476658.1|flybase:FBgn0002962|dip:DIP-23696N|ensemblmetazoa:FBgn0002962(gene)|ensemblmetazoa:FBtr0083732(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007280"(pole cell migration)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035282"(segmentation)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045495"(pole plasm)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0098975"(postsynapse of neuromuscular junction)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR008705(Zinc finger, Nanos)|interpro:IPR024161|interpro:IPR038129|rcsb pdb:5KL1|rcsb pdb:5KL8 pubmed:11060247(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xiN4nWnlbAAHM/WDCZDRsbgoyH47227 rogid:Odk9EPZ9mhtw2sC1379nInFonas7227 intact-crc:EFE3B2D3954BDA7F|rigid:gf7okYyC41ADFxBhz6qOw6USl8o false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P48598 uniprotkb:Q9VMA3 intact:EBI-198574|uniprotkb:Q95SV3|uniprotkb:Q9VSX8|uniprotkb:Q9VSX9|uniprotkb:A4V1Q6|ensemblmetazoa:FBpp0076215|ensemblmetazoa:FBpp0076217|ensemblmetazoa:FBpp0076218|ensemblmetazoa:FBpp0076219|ensemblmetazoa:FBpp0076220|ensemblmetazoa:FBpp0076221|ensemblmetazoa:FBpp0306016|ensemblmetazoa:FBpp0306017 intact:EBI-95398|uniprotkb:O02432|intact:EBI-3427114|ensemblmetazoa:FBpp0288761|ensemblmetazoa:FBpp0312102 psi-mi:if4e_drome(display_long)|uniprotkb:eIF4E1(gene name)|psi-mi:eIF4E1(display_short)|uniprotkb:Eif4e(gene name synonym)|uniprotkb:eIF-4E(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:CG4035(orf name) psi-mi:cup_drome(display_long)|uniprotkb:cup(gene name)|psi-mi:cup(display_short)|uniprotkb:"fs(2)cup"(gene name synonym)|uniprotkb:Oskar ribonucleoprotein complex 147 kDa subunit(gene name synonym)|uniprotkb:CG11181(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872222 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001261626.1|refseq:NP_001261627.1|refseq:NP_524829.1|refseq:NP_729480.1|refseq:NP_729481.1|refseq:NP_729482.1|refseq:NP_729483.1|refseq:NP_729484.1|refseq:NP_729485.1|flybase:FBgn0015218|dip:DIP-17448N|ensemblmetazoa:FBgn0015218(gene)|ensemblmetazoa:FBtr0076487(transcript)|ensemblmetazoa:FBtr0076489(transcript)|ensemblmetazoa:FBtr0076490(transcript)|ensemblmetazoa:FBtr0076491(transcript)|ensemblmetazoa:FBtr0076492(transcript)|ensemblmetazoa:FBtr0076493(transcript)|ensemblmetazoa:FBtr0333884(transcript)|ensemblmetazoa:FBtr0333885(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045182"(translation regulator activity)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098794"(postsynapse)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|rcsb pdb:4AXG|rcsb pdb:4UE8|rcsb pdb:4UE9|rcsb pdb:4UEA|rcsb pdb:4UEB|rcsb pdb:4UEC|rcsb pdb:5ABU|rcsb pdb:5ABV|rcsb pdb:5T47|rcsb pdb:5T48|reactome:R-DME-110523|reactome:R-DME-1169408|reactome:R-DME-156827|reactome:R-DME-159227|reactome:R-DME-159230|reactome:R-DME-159231|reactome:R-DME-166208|reactome:R-DME-429947|reactome:R-DME-72649|reactome:R-DME-72662|reactome:R-DME-72702 refseq:NP_001285687.1|refseq:NP_523493.3|flybase:FBgn0000392|ensemblmetazoa:FBgn0000392(gene)|ensemblmetazoa:FBtr0290322(transcript)|ensemblmetazoa:FBtr0346452(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007319"(negative regulation of oskar mRNA translation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030715"(oocyte growth in germarium-derived egg chamber)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0043195"(terminal bouton)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048477"(oogenesis)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:1905536"(negative regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR018862|rcsb pdb:4AXG|dip:DIP-17920N pubmed:14691132(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:htX4CrNeZ/TE59IjlVxQ9GeQdxk7227 rogid:xiN4nWnlbAAHM/WDCZDRsbgoyH47227 intact-crc:ABDE3E3F761AB3D6|rigid:cxprloZIUitNWhMtj8Gd11jQ7BM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P50445 uniprotkb:P14785 intact:EBI-166782|uniprotkb:Q540W5|uniprotkb:Q9W446|ensemblmetazoa:FBpp0070854|ensemblmetazoa:FBpp0298289 intact:EBI-240333|uniprotkb:Q8IGR7|uniprotkb:Q9VTP6|uniprotkb:Q9VTP7|ensemblmetazoa:FBpp0075807 psi-mi:rux_drome(display_long)|uniprotkb:rux(gene name)|psi-mi:rux(display_short)|uniprotkb:CG4336(orf name) psi-mi:ccna_drome(display_long)|uniprotkb:CycA(gene name)|psi-mi:CycA(display_short)|uniprotkb:CG5940(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872226 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511053.2|flybase:FBgn0003302|refseq:NP_001245540.1|ensemblmetazoa:FBgn0003302(gene)|ensemblmetazoa:FBtr0070889(transcript)|ensemblmetazoa:FBtr0307288(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR009259(Drosophila roughex)|dip:DIP-23711N refseq:NP_524030.2|flybase:FBgn0000404|dip:DIP-22019N|ensemblmetazoa:FBgn0000404(gene)|ensemblmetazoa:FBtr0076075(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045169"(fusome)|go:"GO:0045170"(spectrosome)|go:"GO:0045202"(synapse)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0097124"(cyclin A2-CDK2 complex)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P14785|reactome:R-DME-1538133|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-5689880|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69273|reactome:R-DME-69563|reactome:R-DME-69656 pubmed:11231149(see-also)|pubmed:11027291(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Suf5Lwme/fBq9AKJtz/E3Bip5kk7227 rogid:Ym2ygZ2vFqtDFvZiyifYjRJ7K5c7227 intact-crc:DECF9CE160DAE5BE|rigid:RfsMjcU+9S/qRXmx9+H3ywvO6Fs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24044 uniprotkb:P14785 intact:EBI-176696|ensemblmetazoa:FBpp0080391 intact:EBI-240333|uniprotkb:Q8IGR7|uniprotkb:Q9VTP6|uniprotkb:Q9VTP7|ensemblmetazoa:FBpp0075807 psi-mi:q24044_drome(display_long)|uniprotkb:fzy-RA(gene name synonym)|uniprotkb:fzy(gene name)|psi-mi:fzy(display_short)|uniprotkb:Dmel_CG4274(orf name)|uniprotkb:"BG:DS02740.14"(gene name synonym)|uniprotkb:CDC20(gene name synonym)|uniprotkb:Cdc20(gene name synonym)|uniprotkb:Cdc20[Fzy](gene name synonym)|uniprotkb:Cdc20[fizzy](gene name synonym)|uniprotkb:Dmel\CG4274(gene name synonym)|uniprotkb:FZY(gene name synonym)|uniprotkb:Fizzy(gene name synonym)|uniprotkb:Fzy(gene name synonym)|uniprotkb:cdc20(gene name synonym)|uniprotkb:dCDC20(gene name synonym)|uniprotkb:dFZY(gene name synonym)|uniprotkb:fizzy(gene name synonym)|uniprotkb:CG4274(orf name)|uniprotkb:Cdc20FZY(gene name synonym)|uniprotkb:cdc2(gene name synonym) psi-mi:ccna_drome(display_long)|uniprotkb:CycA(gene name)|psi-mi:CycA(display_short)|uniprotkb:CG5940(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872230 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477501.1|flybase:FBgn0001086|dip:DIP-60667N|ensemblmetazoa:FBgn0001086(gene)|ensemblmetazoa:FBtr0080833(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0007144"(female meiosis I)|go:"GO:0007147"(female meiosis II)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0060547"(negative regulation of necrotic cell death)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q24044|reactome:R-DME-141405|reactome:R-DME-141430|reactome:R-DME-174048|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-176407|reactome:R-DME-176408|reactome:R-DME-176409|reactome:R-DME-176417|reactome:R-DME-179409|reactome:R-DME-2467813|reactome:R-DME-983168 refseq:NP_524030.2|flybase:FBgn0000404|dip:DIP-22019N|ensemblmetazoa:FBgn0000404(gene)|ensemblmetazoa:FBtr0076075(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045169"(fusome)|go:"GO:0045170"(spectrosome)|go:"GO:0045202"(synapse)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0097124"(cyclin A2-CDK2 complex)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P14785|reactome:R-DME-1538133|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-5689880|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69273|reactome:R-DME-69563|reactome:R-DME-69656 pubmed:7730407(see-also)|pubmed:7588612(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:o3IV0N/UEpFvqMOFNx4/bxLUUV87227 rogid:Ym2ygZ2vFqtDFvZiyifYjRJ7K5c7227 intact-crc:17FED41BB698597F|rigid:4/PZ/fFidv4LEUcTrXJm3vvMJYU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VDG2 uniprotkb:P20439 intact:EBI-173258|uniprotkb:O96392|uniprotkb:Q8MZ58|ensemblmetazoa:FBpp0083406 intact:EBI-190039|uniprotkb:Q0E8Y2|uniprotkb:Q8MME2|uniprotkb:Q9I7V2|uniprotkb:Q9TYH6|uniprotkb:Q9TYH7|uniprotkb:Q9V3F4|ensemblmetazoa:FBpp0071822 psi-mi:rlip_drome(display_long)|uniprotkb:Rlip(gene name)|psi-mi:Rlip(display_short)|uniprotkb:CG11622(orf name)|uniprotkb:Ral-interacting protein 1(gene name synonym) psi-mi:ccnb_drome(display_long)|uniprotkb:CycB(gene name)|psi-mi:CycB(display_short)|uniprotkb:CG3510(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872234 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650933.2|flybase:FBgn0026056|ensemblmetazoa:FBgn0026056(gene)|ensemblmetazoa:FBtr0084002(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046578"(regulation of Ras protein signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|reactome:R-DME-9013148|reactome:R-DME-9013149 refseq:NP_726245.2|refseq:NP_726244.1|refseq:NP_726246.1|refseq:NP_726247.1|flybase:FBgn0000405|ensemblmetazoa:FBgn0000405(gene)|ensemblmetazoa:FBtr0071911(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0048134"(germ-line cyst formation)|go:"GO:0051233"(spindle midzone)|go:"GO:0061952"(midbody abscission)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P20439|reactome:R-DME-174048|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166 pubmed:12775724(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:yFklQl4olbZi9X62QgjH3VbyGzE7227 rogid:189MafBrFMpT06ZsFFwvx1UWPHw7227 intact-crc:4FDF46105807CF65|rigid:7uZ42ICOLmjJgVnRJMFiiMYUdPc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O46308 uniprotkb:P20439 intact:EBI-137864|ensemblmetazoa:FBpp0070225 intact:EBI-190039|uniprotkb:Q0E8Y2|uniprotkb:Q8MME2|uniprotkb:Q9I7V2|uniprotkb:Q9TYH6|uniprotkb:Q9TYH7|uniprotkb:Q9V3F4|ensemblmetazoa:FBpp0071822 psi-mi:o46308_drome(display_long)|uniprotkb:png(gene name)|psi-mi:png(display_short)|uniprotkb:"EG:8D8.5"(gene name synonym)|uniprotkb:Dmel\CG11420(gene name synonym)|uniprotkb:PNG(gene name synonym)|uniprotkb:Png(gene name synonym)|uniprotkb:"fs(1)M2"(gene name synonym)|uniprotkb:pan-gnu(gene name synonym)|uniprotkb:Dmel_CG11420(orf name)|uniprotkb:"fs(1)N"(gene name synonym)|uniprotkb:CG11420(orf name) psi-mi:ccnb_drome(display_long)|uniprotkb:CycB(gene name)|psi-mi:CycB(display_short)|uniprotkb:CG3510(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872238 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477492.1|flybase:FBgn0000826|dip:DIP-19818N|ensemblmetazoa:FBgn0000826(gene)|ensemblmetazoa:FBtr0070234(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007343"(egg activation)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1902911"(protein kinase complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like) refseq:NP_726245.2|refseq:NP_726244.1|refseq:NP_726246.1|refseq:NP_726247.1|flybase:FBgn0000405|ensemblmetazoa:FBgn0000405(gene)|ensemblmetazoa:FBtr0071911(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0048134"(germ-line cyst formation)|go:"GO:0051233"(spindle midzone)|go:"GO:0061952"(midbody abscission)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P20439|reactome:R-DME-174048|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166 pubmed:11044392(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:edS/8LZU3aJj4+A1YmKxmD5wQY87227 rogid:189MafBrFMpT06ZsFFwvx1UWPHw7227 intact-crc:C59368A88188BE44|rigid:YDwElBStRGG8edDAi1/qwlp0Xck false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24044 uniprotkb:P20439 intact:EBI-176696|ensemblmetazoa:FBpp0080391 intact:EBI-190039|uniprotkb:Q0E8Y2|uniprotkb:Q8MME2|uniprotkb:Q9I7V2|uniprotkb:Q9TYH6|uniprotkb:Q9TYH7|uniprotkb:Q9V3F4|ensemblmetazoa:FBpp0071822 psi-mi:q24044_drome(display_long)|uniprotkb:fzy-RA(gene name synonym)|uniprotkb:fzy(gene name)|psi-mi:fzy(display_short)|uniprotkb:Dmel_CG4274(orf name)|uniprotkb:"BG:DS02740.14"(gene name synonym)|uniprotkb:CDC20(gene name synonym)|uniprotkb:Cdc20(gene name synonym)|uniprotkb:Cdc20[Fzy](gene name synonym)|uniprotkb:Cdc20[fizzy](gene name synonym)|uniprotkb:Dmel\CG4274(gene name synonym)|uniprotkb:FZY(gene name synonym)|uniprotkb:Fizzy(gene name synonym)|uniprotkb:Fzy(gene name synonym)|uniprotkb:cdc20(gene name synonym)|uniprotkb:dCDC20(gene name synonym)|uniprotkb:dFZY(gene name synonym)|uniprotkb:fizzy(gene name synonym)|uniprotkb:CG4274(orf name)|uniprotkb:Cdc20FZY(gene name synonym)|uniprotkb:cdc2(gene name synonym) psi-mi:ccnb_drome(display_long)|uniprotkb:CycB(gene name)|psi-mi:CycB(display_short)|uniprotkb:CG3510(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872242 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477501.1|flybase:FBgn0001086|dip:DIP-60667N|ensemblmetazoa:FBgn0001086(gene)|ensemblmetazoa:FBtr0080833(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0007144"(female meiosis I)|go:"GO:0007147"(female meiosis II)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0060547"(negative regulation of necrotic cell death)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q24044|reactome:R-DME-141405|reactome:R-DME-141430|reactome:R-DME-174048|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-176407|reactome:R-DME-176408|reactome:R-DME-176409|reactome:R-DME-176417|reactome:R-DME-179409|reactome:R-DME-2467813|reactome:R-DME-983168 refseq:NP_726245.2|refseq:NP_726244.1|refseq:NP_726246.1|refseq:NP_726247.1|flybase:FBgn0000405|ensemblmetazoa:FBgn0000405(gene)|ensemblmetazoa:FBtr0071911(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0048134"(germ-line cyst formation)|go:"GO:0051233"(spindle midzone)|go:"GO:0061952"(midbody abscission)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P20439|reactome:R-DME-174048|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166 pubmed:7730407(see-also)|pubmed:7588612(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:o3IV0N/UEpFvqMOFNx4/bxLUUV87227 rogid:189MafBrFMpT06ZsFFwvx1UWPHw7227 intact-crc:C1CDA5DD8AD9B002|rigid:RNTXMMYF85F75W7UTU1a9iHCiiY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24044 uniprotkb:Q9I7I0 intact:EBI-176696|ensemblmetazoa:FBpp0080391 intact:EBI-150964|uniprotkb:O96718|uniprotkb:Q9TYG8|ensemblmetazoa:FBpp0084103|ensemblmetazoa:FBpp0306645 psi-mi:q24044_drome(display_long)|uniprotkb:fzy-RA(gene name synonym)|uniprotkb:fzy(gene name)|psi-mi:fzy(display_short)|uniprotkb:Dmel_CG4274(orf name)|uniprotkb:"BG:DS02740.14"(gene name synonym)|uniprotkb:CDC20(gene name synonym)|uniprotkb:Cdc20(gene name synonym)|uniprotkb:Cdc20[Fzy](gene name synonym)|uniprotkb:Cdc20[fizzy](gene name synonym)|uniprotkb:Dmel\CG4274(gene name synonym)|uniprotkb:FZY(gene name synonym)|uniprotkb:Fizzy(gene name synonym)|uniprotkb:Fzy(gene name synonym)|uniprotkb:cdc20(gene name synonym)|uniprotkb:dCDC20(gene name synonym)|uniprotkb:dFZY(gene name synonym)|uniprotkb:fizzy(gene name synonym)|uniprotkb:CG4274(orf name)|uniprotkb:Cdc20FZY(gene name synonym)|uniprotkb:cdc2(gene name synonym) psi-mi:ccnb3_drome(display_long)|uniprotkb:CycB3(gene name)|psi-mi:CycB3(display_short)|uniprotkb:CG5814(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872246 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477501.1|flybase:FBgn0001086|dip:DIP-60667N|ensemblmetazoa:FBgn0001086(gene)|ensemblmetazoa:FBtr0080833(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0007144"(female meiosis I)|go:"GO:0007147"(female meiosis II)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0060547"(negative regulation of necrotic cell death)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q24044|reactome:R-DME-141405|reactome:R-DME-141430|reactome:R-DME-174048|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-176407|reactome:R-DME-176408|reactome:R-DME-176409|reactome:R-DME-176417|reactome:R-DME-179409|reactome:R-DME-2467813|reactome:R-DME-983168 refseq:NP_651303.2|flybase:FBgn0015625|refseq:NP_001262934.1|dip:DIP-22205N|ensemblmetazoa:FBgn0015625(gene)|ensemblmetazoa:FBtr0084728(transcript)|ensemblmetazoa:FBtr0334578(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015452(G2/mitotic-specific cyclin B3)|interpro:IPR036915|interpro:IPR039361|mint:Q9I7I0 pubmed:7588612(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:o3IV0N/UEpFvqMOFNx4/bxLUUV87227 rogid:x00iO2ghcNgpERCKftXiPiDv+Is7227 intact-crc:44F41497D9A0EB1B|rigid:BwZOCKBWTdXKHjHQA5KYl64UBvw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24090 uniprotkb:P54733 intact:EBI-151570|ensemblmetazoa:FBpp0078331 intact:EBI-203549|intact:EBI-1628120|uniprotkb:Q24479|uniprotkb:Q95RP5|uniprotkb:Q9V3B3|uniprotkb:Q9V456|ensemblmetazoa:FBpp0080331|ensemblmetazoa:FBpp0080332|ensemblmetazoa:FBpp0080333|ensemblmetazoa:FBpp0080334 psi-mi:q24090_drome(display_long)|uniprotkb:Snr1(gene name)|psi-mi:Snr1(display_short)|uniprotkb:BAP45(gene name synonym)|uniprotkb:Dmel\CG1064(gene name synonym)|uniprotkb:SNR1(gene name synonym)|uniprotkb:Snr(gene name synonym)|uniprotkb:Snr-1(gene name synonym)|uniprotkb:"l(3)01319"(gene name synonym)|uniprotkb:snr(gene name synonym)|uniprotkb:snr-1(gene name synonym)|uniprotkb:snr1(gene name synonym)|uniprotkb:Dmel_CG1064(orf name)|uniprotkb:CG1064(orf name) psi-mi:ccne_drome(display_long)|uniprotkb:CycE(gene name)|psi-mi:CycE(display_short)|uniprotkb:CG3938(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872250 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_730935.1|flybase:FBgn0011715|dip:DIP-17554N|ensemblmetazoa:FBgn0011715(gene)|ensemblmetazoa:FBtr0078682(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035060"(brahma complex)|go:"GO:0043044"|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070983"(dendrite guidance)|go:"GO:0070984"(SET domain binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|mint:Q24090|reactome:R-DME-3214858|reactome:R-DME-8939243 refseq:NP_476959.1|refseq:NP_476960.1|refseq:NP_723924.1|refseq:NP_723925.1|refseq:NP_723926.1|flybase:FBgn0010382|dip:DIP-18331N|ensemblmetazoa:FBgn0010382(gene)|ensemblmetazoa:FBtr0080773(transcript)|ensemblmetazoa:FBtr0080774(transcript)|ensemblmetazoa:FBtr0080775(transcript)|ensemblmetazoa:FBtr0080776(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007277"(pole cell development)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035736"(cell proliferation involved in compound eye morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048665"(neuron fate specification)|go:"GO:0090210"(regulation of establishment of blood-brain barrier)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P54733|reactome:R-DME-1538133|reactome:R-DME-187577|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-9706019 pubmed:12093739(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:fKg0O+kw3EfuBuHr8S9MQNxAugU7227 rogid:AwK/vwBDPgICbmeNxOxrcsj5kiQ7227 intact-crc:ABDB099F3944A73F|rigid:+QZSjBKQ/H1dawzf8yUIhHU7ZRw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P50445 uniprotkb:P54733 intact:EBI-166782|uniprotkb:Q540W5|uniprotkb:Q9W446|ensemblmetazoa:FBpp0070854|ensemblmetazoa:FBpp0298289 intact:EBI-203549|intact:EBI-1628120|uniprotkb:Q24479|uniprotkb:Q95RP5|uniprotkb:Q9V3B3|uniprotkb:Q9V456|ensemblmetazoa:FBpp0080331|ensemblmetazoa:FBpp0080332|ensemblmetazoa:FBpp0080333|ensemblmetazoa:FBpp0080334 psi-mi:rux_drome(display_long)|uniprotkb:rux(gene name)|psi-mi:rux(display_short)|uniprotkb:CG4336(orf name) psi-mi:ccne_drome(display_long)|uniprotkb:CycE(gene name)|psi-mi:CycE(display_short)|uniprotkb:CG3938(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872254 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511053.2|flybase:FBgn0003302|refseq:NP_001245540.1|ensemblmetazoa:FBgn0003302(gene)|ensemblmetazoa:FBtr0070889(transcript)|ensemblmetazoa:FBtr0307288(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR009259(Drosophila roughex)|dip:DIP-23711N refseq:NP_476959.1|refseq:NP_476960.1|refseq:NP_723924.1|refseq:NP_723925.1|refseq:NP_723926.1|flybase:FBgn0010382|dip:DIP-18331N|ensemblmetazoa:FBgn0010382(gene)|ensemblmetazoa:FBtr0080773(transcript)|ensemblmetazoa:FBtr0080774(transcript)|ensemblmetazoa:FBtr0080775(transcript)|ensemblmetazoa:FBtr0080776(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007277"(pole cell development)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035736"(cell proliferation involved in compound eye morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048665"(neuron fate specification)|go:"GO:0090210"(regulation of establishment of blood-brain barrier)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P54733|reactome:R-DME-1538133|reactome:R-DME-187577|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-9706019 pubmed:9171373(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Suf5Lwme/fBq9AKJtz/E3Bip5kk7227 rogid:AwK/vwBDPgICbmeNxOxrcsj5kiQ7227 intact-crc:B9FD96CF91FB6EE2|rigid:+zo7xMmCVweEhmUT9pomxHYq+X4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24472 uniprotkb:P54733 intact:EBI-145741|uniprotkb:O77272|uniprotkb:Q961U8|ensemblmetazoa:FBpp0070141 intact:EBI-203549|intact:EBI-1628120|uniprotkb:Q24479|uniprotkb:Q95RP5|uniprotkb:Q9V3B3|uniprotkb:Q9V456|ensemblmetazoa:FBpp0080331|ensemblmetazoa:FBpp0080332|ensemblmetazoa:FBpp0080333|ensemblmetazoa:FBpp0080334 psi-mi:rbf_drome(display_long)|uniprotkb:Rbf(gene name)|psi-mi:Rbf(display_short)|uniprotkb:CG7413(orf name) psi-mi:ccne_drome(display_long)|uniprotkb:CycE(gene name)|psi-mi:CycE(display_short)|uniprotkb:CG3938(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872258 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525036.2|flybase:FBgn0015799|dip:DIP-34025N|ensemblmetazoa:FBgn0015799(gene)|ensemblmetazoa:FBtr0070146(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007113"(endomitotic cell cycle)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008361"(regulation of cell size)|reactome:R-DME-69231|reactome:R-DME-2173796|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0030154"(cell differentiation)|go:"GO:0031523"(Myb complex)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042594"(response to starvation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:1900117"(regulation of execution phase of apoptosis)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|reactome:R-DME-1538133|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage) refseq:NP_476959.1|refseq:NP_476960.1|refseq:NP_723924.1|refseq:NP_723925.1|refseq:NP_723926.1|flybase:FBgn0010382|dip:DIP-18331N|ensemblmetazoa:FBgn0010382(gene)|ensemblmetazoa:FBtr0080773(transcript)|ensemblmetazoa:FBtr0080774(transcript)|ensemblmetazoa:FBtr0080775(transcript)|ensemblmetazoa:FBtr0080776(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007277"(pole cell development)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035736"(cell proliferation involved in compound eye morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048665"(neuron fate specification)|go:"GO:0090210"(regulation of establishment of blood-brain barrier)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P54733|reactome:R-DME-1538133|reactome:R-DME-187577|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-9706019 pubmed:9691043(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Z0pdwbec8RKtU9vh7XTH1yrBrHs7227 rogid:AwK/vwBDPgICbmeNxOxrcsj5kiQ7227 intact-crc:B714F7DB0F27E0AC|rigid:z/K7xVQy2v/ldUCQS+EOBxrqOJQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P91654 uniprotkb:P54733 intact:EBI-868936|intact:EBI-1627645 intact:EBI-203549|intact:EBI-1628120|uniprotkb:Q24479|uniprotkb:Q95RP5|uniprotkb:Q9V3B3|uniprotkb:Q9V456|ensemblmetazoa:FBpp0080331|ensemblmetazoa:FBpp0080332|ensemblmetazoa:FBpp0080333|ensemblmetazoa:FBpp0080334 psi-mi:p91654_drome(display_long)|uniprotkb:dap(gene name)|psi-mi:dap(display_short)|uniprotkb:dacapo(gene name synonym)|uniprotkb:CG1772(orf name) psi-mi:ccne_drome(display_long)|uniprotkb:CycE(gene name)|psi-mi:CycE(display_short)|uniprotkb:CG3938(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872262 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0010316|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048477"(oogenesis)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003175(Cyclin-dependent kinase inhibitor) refseq:NP_476959.1|refseq:NP_476960.1|refseq:NP_723924.1|refseq:NP_723925.1|refseq:NP_723926.1|flybase:FBgn0010382|dip:DIP-18331N|ensemblmetazoa:FBgn0010382(gene)|ensemblmetazoa:FBtr0080773(transcript)|ensemblmetazoa:FBtr0080774(transcript)|ensemblmetazoa:FBtr0080775(transcript)|ensemblmetazoa:FBtr0080776(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007277"(pole cell development)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035736"(cell proliferation involved in compound eye morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048665"(neuron fate specification)|go:"GO:0090210"(regulation of establishment of blood-brain barrier)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P54733|reactome:R-DME-1538133|reactome:R-DME-187577|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-9706019 pubmed:11784102(see-also)|pubmed:9691043(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ntkvuc9a0N4KShJCJrbHYgpwBS47227 rogid:AwK/vwBDPgICbmeNxOxrcsj5kiQ7227 intact-crc:D1E163FCB8CAA5C3|rigid:+w2zLT4PXJUKLStcORdmsI7orj8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16241 uniprotkb:Q24533 intact:EBI-132677|uniprotkb:Q24460|uniprotkb:Q86P26|uniprotkb:Q9VRY9|ensemblmetazoa:FBpp0076653|ensemblmetazoa:FBpp0311831 intact:EBI-147892|uniprotkb:A2VED6|uniprotkb:Q8MSP8|uniprotkb:Q9VUD4|ensemblmetazoa:FBpp0075488|ensemblmetazoa:FBpp0305248|ensemblmetazoa:FBpp0305249|ensemblmetazoa:FBpp0305250 psi-mi:cf1a_drome(display_long)|uniprotkb:CG10037(orf name)|uniprotkb:vvl(gene name)|psi-mi:vvl(display_short)|uniprotkb:Cf1a(gene name synonym)|uniprotkb:Chorion factor 1A(gene name synonym)|uniprotkb:Ventral veins lacking protein(gene name synonym)|uniprotkb:Protein drifter(gene name synonym) psi-mi:dich_drome(display_long)|uniprotkb:D(gene name)|psi-mi:D(display_short)|uniprotkb:fish(gene name synonym)|uniprotkb:Sox70D(gene name synonym)|uniprotkb:CG5893(orf name)|uniprotkb:Protein fish-hook(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872270 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523948.1|flybase:FBgn0086680|refseq:NP_001286957.1|ensemblmetazoa:FBgn0086680(gene)|ensemblmetazoa:FBtr0076944(transcript)|ensemblmetazoa:FBtr0345911(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002807"(positive regulation of antimicrobial peptide biosynthetic process)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0035284"(brain segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR016362(Transcription factor, homeobox/POU)|interpro:IPR017970|dip:DIP-17200N refseq:NP_524066.1|flybase:FBgn0000411|refseq:NP_001261830.1|refseq:NP_001261831.1|refseq:NP_001261832.1|dip:DIP-21577N|ensemblmetazoa:FBgn0000411(gene)|ensemblmetazoa:FBtr0075746(transcript)|ensemblmetazoa:FBtr0333034(transcript)|ensemblmetazoa:FBtr0333035(transcript)|ensemblmetazoa:FBtr0333036(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002168"(instar larval development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035120"(post-embryonic appendage morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0070983"(dendrite guidance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-DME-3769402|go:"GO:0008301"(DNA binding, bending) pubmed:10844029(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:5KOEjYBWVSLPmVYoSIRHX3/NbcU7227 rogid:7F+gCqXkLD0BTK3K/BHJEIEKW6s7227 intact-crc:E1FB7B09002C18FF|rigid:yhn8DRla627l5JnjHS6lXpW97BU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24119 uniprotkb:Q24533 intact:EBI-867721|uniprotkb:Q24165|uniprotkb:Q8SX13|uniprotkb:Q9W0Q7|uniprotkb:A8JNH0|uniprotkb:A8WHG8|uniprotkb:Q0E8K2|ensemblmetazoa:FBpp0303179 intact:EBI-147892|uniprotkb:A2VED6|uniprotkb:Q8MSP8|uniprotkb:Q9VUD4|ensemblmetazoa:FBpp0075488|ensemblmetazoa:FBpp0305248|ensemblmetazoa:FBpp0305249|ensemblmetazoa:FBpp0305250 psi-mi:trh_drome(display_long)|uniprotkb:trh(gene name)|psi-mi:trh(display_short)|uniprotkb:CG6883(orf name) psi-mi:dich_drome(display_long)|uniprotkb:D(gene name)|psi-mi:D(display_short)|uniprotkb:fish(gene name synonym)|uniprotkb:Sox70D(gene name synonym)|uniprotkb:CG5893(orf name)|uniprotkb:Protein fish-hook(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872274 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036575.1|refseq:NP_001097461.2|refseq:NP_523872.2|flybase:FBgn0262139|refseq:NP_001261207.1|ensemblmetazoa:FBgn0262139(gene)|ensemblmetazoa:FBtr0330146(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007425"(epithelial cell fate determination, open tracheal system)|go:"GO:0007431"(salivary gland development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048736"(appendage development)|go:"GO:0072175"(epithelial tube formation)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638 refseq:NP_524066.1|flybase:FBgn0000411|refseq:NP_001261830.1|refseq:NP_001261831.1|refseq:NP_001261832.1|dip:DIP-21577N|ensemblmetazoa:FBgn0000411(gene)|ensemblmetazoa:FBtr0075746(transcript)|ensemblmetazoa:FBtr0333034(transcript)|ensemblmetazoa:FBtr0333035(transcript)|ensemblmetazoa:FBtr0333036(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002168"(instar larval development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035120"(post-embryonic appendage morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0070983"(dendrite guidance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-DME-3769402|go:"GO:0008301"(DNA binding, bending) pubmed:10844029(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Kpsq6NkJNU789aMg3CMeZGq2kgw7227 rogid:7F+gCqXkLD0BTK3K/BHJEIEKW6s7227 intact-crc:38222A8BEB3F59AB|rigid:Cmyga5I5N5KVjGpjZp0aseQMPfo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P05709 uniprotkb:Q24533 intact:EBI-88929|uniprotkb:O96521|uniprotkb:Q7KSL7|uniprotkb:Q8MQI7|uniprotkb:Q9VFZ3|intact:EBI-3426277 intact:EBI-147892|uniprotkb:A2VED6|uniprotkb:Q8MSP8|uniprotkb:Q9VUD4|ensemblmetazoa:FBpp0075488|ensemblmetazoa:FBpp0305248|ensemblmetazoa:FBpp0305249|ensemblmetazoa:FBpp0305250 psi-mi:sim_drome(display_long)|uniprotkb:sim(gene name)|psi-mi:sim(display_short)|uniprotkb:CG7771(orf name) psi-mi:dich_drome(display_long)|uniprotkb:D(gene name)|psi-mi:D(display_short)|uniprotkb:fish(gene name synonym)|uniprotkb:Sox70D(gene name synonym)|uniprotkb:CG5893(orf name)|uniprotkb:Protein fish-hook(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872278 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524340.2|refseq:NP_731771.3|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007398"(ectoderm development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007418"(ventral midline development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007420"(brain development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0040011"(locomotion)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000014(PAS)|go:"GO:0003700"(DNA-binding transcription factor activity)|flybase:FBgn0004666 refseq:NP_524066.1|flybase:FBgn0000411|refseq:NP_001261830.1|refseq:NP_001261831.1|refseq:NP_001261832.1|dip:DIP-21577N|ensemblmetazoa:FBgn0000411(gene)|ensemblmetazoa:FBtr0075746(transcript)|ensemblmetazoa:FBtr0333034(transcript)|ensemblmetazoa:FBtr0333035(transcript)|ensemblmetazoa:FBtr0333036(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002168"(instar larval development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035120"(post-embryonic appendage morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0070983"(dendrite guidance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-DME-3769402|go:"GO:0008301"(DNA binding, bending) pubmed:10844029(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Xj4MTmDPyNDCBHuTSv9zZgIfvO07227 rogid:7F+gCqXkLD0BTK3K/BHJEIEKW6s7227 intact-crc:3BCCF902B9C20561|rigid:V2cXA7dQ1kmO7FLmFbCIky9uiME false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24533 uniprotkb:P07663 intact:EBI-147892|uniprotkb:A2VED6|uniprotkb:Q8MSP8|uniprotkb:Q9VUD4|ensemblmetazoa:FBpp0075488|ensemblmetazoa:FBpp0305248|ensemblmetazoa:FBpp0305249|ensemblmetazoa:FBpp0305250 intact:EBI-496170|uniprotkb:O17483|uniprotkb:O76882|uniprotkb:O76883|uniprotkb:O76884|uniprotkb:O76885|uniprotkb:Q24446|uniprotkb:Q24447|uniprotkb:Q24448|uniprotkb:Q24449|uniprotkb:Q6PVA3|uniprotkb:Q8MLY0|uniprotkb:Q9GN20|uniprotkb:Q9GN51|uniprotkb:Q9GQH9|uniprotkb:Q9GV48|uniprotkb:Q9GV53|uniprotkb:Q9GV54|uniprotkb:Q9GV55|uniprotkb:Q9W4X0|ensemblmetazoa:FBpp0070455 psi-mi:dich_drome(display_long)|uniprotkb:D(gene name)|psi-mi:D(display_short)|uniprotkb:fish(gene name synonym)|uniprotkb:Sox70D(gene name synonym)|uniprotkb:CG5893(orf name)|uniprotkb:Protein fish-hook(gene name synonym) psi-mi:per_drome(display_long)|uniprotkb:Protein clock-6(gene name synonym)|uniprotkb:per(gene name)|psi-mi:per(display_short)|uniprotkb:CG2647(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872282 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524066.1|flybase:FBgn0000411|refseq:NP_001261830.1|refseq:NP_001261831.1|refseq:NP_001261832.1|dip:DIP-21577N|ensemblmetazoa:FBgn0000411(gene)|ensemblmetazoa:FBtr0075746(transcript)|ensemblmetazoa:FBtr0333034(transcript)|ensemblmetazoa:FBtr0333035(transcript)|ensemblmetazoa:FBtr0333036(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002168"(instar larval development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035120"(post-embryonic appendage morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0070983"(dendrite guidance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-DME-3769402|go:"GO:0008301"(DNA binding, bending) refseq:NP_525056.2|flybase:FBgn0003068|refseq:NP_001259194.1|dip:DIP-29426N|ensemblmetazoa:FBgn0003068(gene)|ensemblmetazoa:FBtr0070477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001306"(age-dependent response to oxidative stress)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007616"(long-term memory)|go:"GO:0007617"(mating behavior)|go:"GO:0007619"(courtship behavior)|go:"GO:0007620"(copulation)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0044297"(cell body)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0048512"(circadian behavior)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR035965|rcsb pdb:1WA9|rcsb pdb:3GEC|rcsb pdb:3RTY|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432524|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 pubmed:10844029(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:7F+gCqXkLD0BTK3K/BHJEIEKW6s7227 rogid:+l/mg+2MJForY5dORYWnWsVAhNI7227 intact-crc:201DBE5CA38E1A0C|rigid:D1bpvrfBcnVER/RInsDLsWBBoiU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24533 uniprotkb:P31369 intact:EBI-147892|uniprotkb:A2VED6|uniprotkb:Q8MSP8|uniprotkb:Q9VUD4|ensemblmetazoa:FBpp0075488|ensemblmetazoa:FBpp0305248|ensemblmetazoa:FBpp0305249|ensemblmetazoa:FBpp0305250 intact:EBI-141169|uniprotkb:Q24430|uniprotkb:Q9VK70|uniprotkb:Q6NR41|ensemblmetazoa:FBpp0079974 psi-mi:dich_drome(display_long)|uniprotkb:D(gene name)|psi-mi:D(display_short)|uniprotkb:fish(gene name synonym)|uniprotkb:Sox70D(gene name synonym)|uniprotkb:CG5893(orf name)|uniprotkb:Protein fish-hook(gene name synonym) psi-mi:pdm2a_drome(display_long)|uniprotkb:pdm2(gene name)|psi-mi:pdm2(display_short)|uniprotkb:pdm-2(gene name synonym)|uniprotkb:dim(gene name synonym)|uniprotkb:OCT2(gene name synonym)|uniprotkb:POU-28(gene name synonym)|uniprotkb:CG12287(orf name)|uniprotkb:Protein didymous(gene name synonym)|uniprotkb:Pdm-2(gene name synonym)|uniprotkb:dPOU-28(gene name synonym)|uniprotkb:dOct2(gene name synonym)|uniprotkb:Miti-mere(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872286 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524066.1|flybase:FBgn0000411|refseq:NP_001261830.1|refseq:NP_001261831.1|refseq:NP_001261832.1|dip:DIP-21577N|ensemblmetazoa:FBgn0000411(gene)|ensemblmetazoa:FBtr0075746(transcript)|ensemblmetazoa:FBtr0333034(transcript)|ensemblmetazoa:FBtr0333035(transcript)|ensemblmetazoa:FBtr0333036(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002168"(instar larval development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035120"(post-embryonic appendage morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0070983"(dendrite guidance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-DME-3769402|go:"GO:0008301"(DNA binding, bending) ensemblmetazoa:FBgn0004394(gene)|ensemblmetazoa:FBtr0080393(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007398"(ectoderm development)|go:"GO:0007417"(central nervous system development)|go:"GO:0014019"(neuroblast development)|go:"GO:0048699"(generation of neurons)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|refseq:NP_523558.2|flybase:FBgn0004394 pubmed:10844029(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:7F+gCqXkLD0BTK3K/BHJEIEKW6s7227 rogid:BrKMZGsxZKjmogMmLCXZupcHics7227 intact-crc:F8990AE2D5ED5651|rigid:jeLC2gERjRVulCMTkkQoy/O9PNg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24533 uniprotkb:P31368 intact:EBI-147892|uniprotkb:A2VED6|uniprotkb:Q8MSP8|uniprotkb:Q9VUD4|ensemblmetazoa:FBpp0075488|ensemblmetazoa:FBpp0305248|ensemblmetazoa:FBpp0305249|ensemblmetazoa:FBpp0305250 intact:EBI-150557|uniprotkb:Q9VK74|ensemblmetazoa:FBpp0111555|ensemblmetazoa:FBpp0309559 psi-mi:dich_drome(display_long)|uniprotkb:D(gene name)|psi-mi:D(display_short)|uniprotkb:fish(gene name synonym)|uniprotkb:Sox70D(gene name synonym)|uniprotkb:CG5893(orf name)|uniprotkb:Protein fish-hook(gene name synonym) psi-mi:pdm1_drome(display_long)|uniprotkb:nub(gene name)|psi-mi:nub(display_short)|uniprotkb:OCT1(gene name synonym)|uniprotkb:pdm-1(gene name synonym)|uniprotkb:POU-19(gene name synonym)|uniprotkb:TWN(gene name synonym)|uniprotkb:POU domain protein 1(gene name synonym)|uniprotkb:dPOU-19(gene name synonym)|uniprotkb:dOCT1(gene name synonym)|uniprotkb:CG34395(orf name)|uniprotkb:Protein twain(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872290 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524066.1|flybase:FBgn0000411|refseq:NP_001261830.1|refseq:NP_001261831.1|refseq:NP_001261832.1|dip:DIP-21577N|ensemblmetazoa:FBgn0000411(gene)|ensemblmetazoa:FBtr0075746(transcript)|ensemblmetazoa:FBtr0333034(transcript)|ensemblmetazoa:FBtr0333035(transcript)|ensemblmetazoa:FBtr0333036(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002168"(instar larval development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035120"(post-embryonic appendage morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0070983"(dendrite guidance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-DME-3769402|go:"GO:0008301"(DNA binding, bending) refseq:NP_476659.1|flybase:FBgn0085424|refseq:NP_001285876.1|ensemblmetazoa:FBgn0085424(gene)|ensemblmetazoa:FBtr0112643(transcript)|ensemblmetazoa:FBtr0342628(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002809"(negative regulation of antibacterial peptide biosynthetic process)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035107"(appendage morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|reactome:R-DME-6807505 pubmed:10844029(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:7F+gCqXkLD0BTK3K/BHJEIEKW6s7227 rogid:KPrV5WNZfP8W/r4lJ746Tc70aP87227 intact-crc:889966FF799D4701|rigid:OIfLgu97xYeI7AnnoAZ2IIocZ5E false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24533 uniprotkb:Q24533 intact:EBI-147892|uniprotkb:A2VED6|uniprotkb:Q8MSP8|uniprotkb:Q9VUD4|ensemblmetazoa:FBpp0075488|ensemblmetazoa:FBpp0305248|ensemblmetazoa:FBpp0305249|ensemblmetazoa:FBpp0305250 intact:EBI-147892|uniprotkb:A2VED6|uniprotkb:Q8MSP8|uniprotkb:Q9VUD4|ensemblmetazoa:FBpp0075488|ensemblmetazoa:FBpp0305248|ensemblmetazoa:FBpp0305249|ensemblmetazoa:FBpp0305250 psi-mi:dich_drome(display_long)|uniprotkb:D(gene name)|psi-mi:D(display_short)|uniprotkb:fish(gene name synonym)|uniprotkb:Sox70D(gene name synonym)|uniprotkb:CG5893(orf name)|uniprotkb:Protein fish-hook(gene name synonym) psi-mi:dich_drome(display_long)|uniprotkb:D(gene name)|psi-mi:D(display_short)|uniprotkb:fish(gene name synonym)|uniprotkb:Sox70D(gene name synonym)|uniprotkb:CG5893(orf name)|uniprotkb:Protein fish-hook(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872294 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524066.1|flybase:FBgn0000411|refseq:NP_001261830.1|refseq:NP_001261831.1|refseq:NP_001261832.1|dip:DIP-21577N|ensemblmetazoa:FBgn0000411(gene)|ensemblmetazoa:FBtr0075746(transcript)|ensemblmetazoa:FBtr0333034(transcript)|ensemblmetazoa:FBtr0333035(transcript)|ensemblmetazoa:FBtr0333036(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002168"(instar larval development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035120"(post-embryonic appendage morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0070983"(dendrite guidance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-DME-3769402|go:"GO:0008301"(DNA binding, bending) refseq:NP_524066.1|flybase:FBgn0000411|refseq:NP_001261830.1|refseq:NP_001261831.1|refseq:NP_001261832.1|dip:DIP-21577N|ensemblmetazoa:FBgn0000411(gene)|ensemblmetazoa:FBtr0075746(transcript)|ensemblmetazoa:FBtr0333034(transcript)|ensemblmetazoa:FBtr0333035(transcript)|ensemblmetazoa:FBtr0333036(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002168"(instar larval development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035120"(post-embryonic appendage morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0070983"(dendrite guidance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-DME-3769402|go:"GO:0008301"(DNA binding, bending) pubmed:10844029(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:7F+gCqXkLD0BTK3K/BHJEIEKW6s7227 rogid:7F+gCqXkLD0BTK3K/BHJEIEKW6s7227 intact-crc:BDDC52845B71A06B|rigid:KPxYhlaAm8uqXspOBiLhqVMme2w false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10627 uniprotkb:P11420 intact:EBI-104826|uniprotkb:Q8MT07|uniprotkb:Q8T8Y9|uniprotkb:Q9W1W1|uniprotkb:Q1LZ34|ensemblmetazoa:FBpp0071864|ensemblmetazoa:FBpp0099476|ensemblmetazoa:FBpp0311714 intact:EBI-151268|intact:EBI-1639097|uniprotkb:Q9VKX3|ensemblmetazoa:FBpp0079598|ensemblmetazoa:FBpp0304504|ensemblmetazoa:FBpp0304505 psi-mi:twist_drome(display_long)|uniprotkb:twi(gene name)|psi-mi:twi(display_short)|uniprotkb:CG2956(orf name) psi-mi:da_drome(display_long)|uniprotkb:da(gene name)|psi-mi:da(display_short)|uniprotkb:CG5102(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872298 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033967.1|refseq:NP_523816.2|flybase:FBgn0003900|refseq:NP_001286752.1|ensemblmetazoa:FBgn0003900(gene)|ensemblmetazoa:FBtr0071953(transcript)|ensemblmetazoa:FBtr0100130(transcript)|ensemblmetazoa:FBtr0345653(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0007507"(heart development)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032502"(developmental process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0055001"(muscle cell development)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015789(Twist)|interpro:IPR036638 go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007423"(sensory organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030237"(female sex determination)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050821"(protein stabilization)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-525793|reactome:R-DME-8939236|go:"GO:0061525"(hindgut development)|flybase:FBgn0267821|ensemblmetazoa:FBgn0267821(gene)|ensemblmetazoa:FBtr0080008(transcript)|ensemblmetazoa:FBtr0332195(transcript)|ensemblmetazoa:FBtr0332196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_477189.1|refseq:NP_001260340.1|refseq:NP_001260341.1|dip:DIP-50N pubmed:11688563(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:opc0LqFf1LFamPnLiKVnBlMgYzs7227 rogid:EwPK9ObnWH1gzRFPpERKnmw/kDA7227 intact-crc:BE8A08B3F405982A|rigid:l0XTP9U3DBw3gX3+nBYJ9YqND3U false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10084 uniprotkb:P11420 intact:EBI-174136|intact:EBI-1639078|uniprotkb:O76890|uniprotkb:Q4V705|ensemblmetazoa:FBpp0070072 intact:EBI-151268|intact:EBI-1639097|uniprotkb:Q9VKX3|ensemblmetazoa:FBpp0079598|ensemblmetazoa:FBpp0304504|ensemblmetazoa:FBpp0304505 psi-mi:ast4_drome(display_long)|uniprotkb:sc(gene name)|psi-mi:sc(display_short)|uniprotkb:T4(gene name synonym)|uniprotkb:Protein scute(gene name synonym)|uniprotkb:sis-b(gene name synonym)|uniprotkb:CG3827(orf name) psi-mi:da_drome(display_long)|uniprotkb:da(gene name)|psi-mi:da(display_short)|uniprotkb:CG5102(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872302 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476803.1|flybase:FBgn0004170|dip:DIP-325N|ensemblmetazoa:FBgn0004170(gene)|ensemblmetazoa:FBtr0070073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638 go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007423"(sensory organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030237"(female sex determination)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050821"(protein stabilization)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-525793|reactome:R-DME-8939236|go:"GO:0061525"(hindgut development)|flybase:FBgn0267821|ensemblmetazoa:FBgn0267821(gene)|ensemblmetazoa:FBtr0080008(transcript)|ensemblmetazoa:FBtr0332195(transcript)|ensemblmetazoa:FBtr0332196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_477189.1|refseq:NP_001260340.1|refseq:NP_001260341.1|dip:DIP-50N pubmed:1915272(see-also)|pubmed:7623836(see-also)|pubmed:1764999(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:WTTmp3SuZ10YiZMKYALr68UiRO07227 rogid:EwPK9ObnWH1gzRFPpERKnmw/kDA7227 intact-crc:22D703A4ED830491|rigid:qqYzgDQzJn5cLnNAQT98CVheLX4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P22816 uniprotkb:P11420 intact:EBI-86779|uniprotkb:Q9VCJ1|ensemblmetazoa:FBpp0083863 intact:EBI-151268|intact:EBI-1639097|uniprotkb:Q9VKX3|ensemblmetazoa:FBpp0079598|ensemblmetazoa:FBpp0304504|ensemblmetazoa:FBpp0304505 psi-mi:myod_drome(display_long)|uniprotkb:nau(gene name)|psi-mi:nau(display_short)|uniprotkb:MYD(gene name synonym)|uniprotkb:dMyd(gene name synonym)|uniprotkb:Protein nautilus(gene name synonym)|uniprotkb:CG10250(orf name) psi-mi:da_drome(display_long)|uniprotkb:da(gene name)|psi-mi:da(display_short)|uniprotkb:CG5102(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872306 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476650.1|flybase:FBgn0002922|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0016204"(determination of muscle attachment site)|go:"GO:0030154"(cell differentiation)|ensemblmetazoa:FBgn0002922(gene)|ensemblmetazoa:FBtr0084472(transcript)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR002546(Myogenic basic muscle-specific protein)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR039704|reactome:R-DME-525793 go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007423"(sensory organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030237"(female sex determination)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050821"(protein stabilization)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-525793|reactome:R-DME-8939236|go:"GO:0061525"(hindgut development)|flybase:FBgn0267821|ensemblmetazoa:FBgn0267821(gene)|ensemblmetazoa:FBtr0080008(transcript)|ensemblmetazoa:FBtr0332195(transcript)|ensemblmetazoa:FBtr0332196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_477189.1|refseq:NP_001260340.1|refseq:NP_001260341.1|dip:DIP-50N pubmed:11112327(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:s13LNQ+5ckI8+PRqkSDVHWkpp307227 rogid:EwPK9ObnWH1gzRFPpERKnmw/kDA7227 intact-crc:5276DB6CCD380E89|rigid:zSrBPPyMgdpPzD+GRcguTiXzsO4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09774 uniprotkb:P11420 intact:EBI-174224|intact:EBI-1628024|uniprotkb:Q24387|uniprotkb:Q8MRA5|ensemblmetazoa:FBpp0070073 intact:EBI-151268|intact:EBI-1639097|uniprotkb:Q9VKX3|ensemblmetazoa:FBpp0079598|ensemblmetazoa:FBpp0304504|ensemblmetazoa:FBpp0304505 psi-mi:ast3_drome(display_long)|uniprotkb:"l(1)sc"(gene name)|psi-mi:"l(1)sc"(display_short)|uniprotkb:T3(gene name synonym)|uniprotkb:l'sc(gene name synonym)|uniprotkb:CG3839(orf name)|uniprotkb:Protein lethal of scute(gene name synonym) psi-mi:da_drome(display_long)|uniprotkb:da(gene name)|psi-mi:da(display_short)|uniprotkb:CG5102(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872310 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476623.1|flybase:FBgn0002561|ensemblmetazoa:FBgn0002561(gene)|ensemblmetazoa:FBtr0070074(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638 go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007423"(sensory organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030237"(female sex determination)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050821"(protein stabilization)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-525793|reactome:R-DME-8939236|go:"GO:0061525"(hindgut development)|flybase:FBgn0267821|ensemblmetazoa:FBgn0267821(gene)|ensemblmetazoa:FBtr0080008(transcript)|ensemblmetazoa:FBtr0332195(transcript)|ensemblmetazoa:FBtr0332196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_477189.1|refseq:NP_001260340.1|refseq:NP_001260341.1|dip:DIP-50N pubmed:1915272(see-also)|pubmed:1764999(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6/qKHfmqMOsi8uWoKA4A3IbeOGk7227 rogid:EwPK9ObnWH1gzRFPpERKnmw/kDA7227 intact-crc:52302B7E74992B2C|rigid:x0m7B+78Dh9vAcB5GthsYElzCfQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O18374 uniprotkb:P11420 intact:EBI-868952 intact:EBI-151268|intact:EBI-1639097|uniprotkb:Q9VKX3|ensemblmetazoa:FBpp0079598|ensemblmetazoa:FBpp0304504|ensemblmetazoa:FBpp0304505 psi-mi:o18374_drome(display_long)|uniprotkb:HLH54F(gene name)|psi-mi:HLH54F(display_short)|uniprotkb:bHLH54F(gene name synonym)|uniprotkb:CG5005(orf name) psi-mi:da_drome(display_long)|uniprotkb:da(gene name)|psi-mi:da(display_short)|uniprotkb:CG5102(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872314 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0022740|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007522"(visceral muscle development)|go:"GO:0032502"(developmental process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007423"(sensory organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030237"(female sex determination)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050821"(protein stabilization)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-525793|reactome:R-DME-8939236|go:"GO:0061525"(hindgut development)|flybase:FBgn0267821|ensemblmetazoa:FBgn0267821(gene)|ensemblmetazoa:FBtr0080008(transcript)|ensemblmetazoa:FBtr0332195(transcript)|ensemblmetazoa:FBtr0332196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_477189.1|refseq:NP_001260340.1|refseq:NP_001260341.1|dip:DIP-50N pubmed:9486535(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:7V4spK5Vq7ci/j8ag1XJ83IB+hQ7227 rogid:EwPK9ObnWH1gzRFPpERKnmw/kDA7227 intact-crc:C3A528F6AC53EFF8|rigid:MreYYv75IY8yIgxrsgrfx8q0z98 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18491 uniprotkb:P11420 intact:EBI-105737|intact:EBI-1639647|uniprotkb:Q9W0N0|intact:EBI-3431186|ensemblmetazoa:FBpp0072477 intact:EBI-151268|intact:EBI-1639097|uniprotkb:Q9VKX3|ensemblmetazoa:FBpp0079598|ensemblmetazoa:FBpp0304504|ensemblmetazoa:FBpp0304505 psi-mi:emc_drome(display_long)|uniprotkb:emc(gene name)|psi-mi:emc(display_short)|uniprotkb:CG1007(orf name) psi-mi:da_drome(display_long)|uniprotkb:da(gene name)|psi-mi:da(display_short)|uniprotkb:CG5102(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872318 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|go:"GO:0046552"(photoreceptor cell fate commitment)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0061525"(hindgut development)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_523876.2|flybase:FBgn0000575|dip:DIP-73N|ensemblmetazoa:FBgn0000575(gene)|ensemblmetazoa:FBtr0072578(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007391"(dorsal closure)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0007530"(sex determination)|go:"GO:0008258"(head involution)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0030154"(cell differentiation) go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007423"(sensory organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0030237"(female sex determination)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0050821"(protein stabilization)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-525793|reactome:R-DME-8939236|go:"GO:0061525"(hindgut development)|flybase:FBgn0267821|ensemblmetazoa:FBgn0267821(gene)|ensemblmetazoa:FBtr0080008(transcript)|ensemblmetazoa:FBtr0332195(transcript)|ensemblmetazoa:FBtr0332196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_477189.1|refseq:NP_001260340.1|refseq:NP_001260341.1|dip:DIP-50N pubmed:7821225(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:JfE7tW1Lu4C7KafkWe31A98gZoM7227 rogid:EwPK9ObnWH1gzRFPpERKnmw/kDA7227 intact-crc:50294C7626D8F75E|rigid:ofEQuiBLSqLFyIBF9DPUXHlSpz0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P13368 uniprotkb:P98081 intact:EBI-522166|uniprotkb:Q9TYI0|uniprotkb:Q9U5V7|uniprotkb:Q9VZ36|ensemblmetazoa:FBpp0073249 intact:EBI-596484|uniprotkb:Q9VV93|ensemblmetazoa:FBpp0075077 psi-mi:7less_drome(display_long)|uniprotkb:sev(gene name)|psi-mi:sev(display_short)|uniprotkb:HD-265(gene name synonym)|uniprotkb:CG18085(orf name) psi-mi:dab_drome(display_long)|uniprotkb:Dab(gene name)|psi-mi:Dab(display_short)|uniprotkb:CG9695(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872322 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511114.2|flybase:FBgn0003366|ensemblmetazoa:FBgn0003366(gene)|go:"GO:0045500"(sevenless signaling pathway)|ensemblmetazoa:FBtr0073393(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008288"(boss receptor activity)|go:"GO:0019199"(transmembrane receptor protein kinase activity)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0043235"(receptor complex)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116 refseq:NP_524119.2|flybase:FBgn0000414|ensemblmetazoa:FBgn0000414(gene)|ensemblmetazoa:FBtr0075318(transcript)|go:"GO:0005118"(sevenless binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007349"(cellularization)|go:"GO:0007391"(dorsal closure)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030424"(axon)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0045874"(positive regulation of sevenless signaling pathway)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098793"(presynapse)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028761|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-8856825|reactome:R-DME-8856828 pubmed:9671493(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:YpmSTbTsxz1LSM+oNtflAISXkIQ7227 rogid:XcOuBhCV6ZOpIOxRpX/qWTa3Xp07227 intact-crc:94F7F3A5DAAF5FF7|rigid:ZfwiLmiw0dsFerrr7JRJIqJas5M false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07207 uniprotkb:P98081 intact:EBI-103438|uniprotkb:O97458|uniprotkb:P04154|uniprotkb:Q9W4T8|ensemblmetazoa:FBpp0070483|ensemblmetazoa:FBpp0293201 intact:EBI-596484|uniprotkb:Q9VV93|ensemblmetazoa:FBpp0075077 psi-mi:notch_drome(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:CG3936(orf name) psi-mi:dab_drome(display_long)|uniprotkb:Dab(gene name)|psi-mi:Dab(display_short)|uniprotkb:CG9695(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872326 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476859.2|flybase:FBgn0004647|ensemblmetazoa:FBgn0004647(gene)|ensemblmetazoa:FBtr0070507(transcript)|ensemblmetazoa:FBtr0304659(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002213"(defense response to insect)|go:"GO:0003682"(chromatin binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007391"(dorsal closure)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009608"(response to symbiont)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0022416"(chaeta development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0007498"(mesoderm development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0007616"(long-term memory)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0040008"(regulation of growth)|go:"GO:0042686"(regulation of cardioblast cell fate specification)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045316"(negative regulation of compound eye photoreceptor development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048627"(myoblast development)|go:"GO:0048664"(neuron fate determination)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050699"(WW domain binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0060289"(compartment boundary maintenance)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990433"(CSL-Notch-Mastermind transcription factor complex)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1OT8|rcsb pdb:2JMF|refseq:NP_001245510.1|dip:DIP-5N refseq:NP_524119.2|flybase:FBgn0000414|ensemblmetazoa:FBgn0000414(gene)|ensemblmetazoa:FBtr0075318(transcript)|go:"GO:0005118"(sevenless binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007349"(cellularization)|go:"GO:0007391"(dorsal closure)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030424"(axon)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0045874"(positive regulation of sevenless signaling pathway)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098793"(presynapse)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028761|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-8856825|reactome:R-DME-8856828 pubmed:9581760(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:T1iHJGMHXkhxbFRybmSDlizN7oQ7227 rogid:XcOuBhCV6ZOpIOxRpX/qWTa3Xp07227 intact-crc:5C78E177AC3B357F|rigid:s+5TjvZr4kY1LWNav/1wcF59NCQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q08012 uniprotkb:P98081 intact:EBI-161391|uniprotkb:Q0E989|uniprotkb:Q9V6Q5|uniprotkb:A4UZF9|ensemblmetazoa:FBpp0086813|ensemblmetazoa:FBpp0086814|ensemblmetazoa:FBpp0086815|ensemblmetazoa:FBpp0086816|ensemblmetazoa:FBpp0086817 intact:EBI-596484|uniprotkb:Q9VV93|ensemblmetazoa:FBpp0075077 psi-mi:grap_drome(display_long)|uniprotkb:drk(gene name)|psi-mi:drk(display_short)|uniprotkb:"E(sev)2B"(gene name synonym)|uniprotkb:Downstream of receptor kinase(gene name synonym)|uniprotkb:Grb2(gene name synonym)|uniprotkb:Protein enhancer of sevenless 2B(gene name synonym)|uniprotkb:CG6033(orf name) psi-mi:dab_drome(display_long)|uniprotkb:Dab(gene name)|psi-mi:Dab(display_short)|uniprotkb:CG9695(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872330 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476858.1|refseq:NP_725302.1|refseq:NP_725303.1|refseq:NP_725304.1|refseq:NP_725306.1|flybase:FBgn0004638|ensemblmetazoa:FBgn0004638(gene)|ensemblmetazoa:FBtr0087694(transcript)|ensemblmetazoa:FBtr0087695(transcript)|ensemblmetazoa:FBtr0087696(transcript)|ensemblmetazoa:FBtr0087697(transcript)|ensemblmetazoa:FBtr0087698(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005118"(sevenless binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007614"(short-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR030219|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2A36|go:"GO:0008306"(associative learning)|rcsb pdb:2A37|rcsb pdb:2AZS|rcsb pdb:2AZV|reactome:R-DME-109704|reactome:R-DME-112412|reactome:R-DME-1250347|reactome:R-DME-1257604|reactome:R-DME-1295596|reactome:R-DME-1433557|reactome:R-DME-1433559|reactome:R-DME-167044|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-1963642|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2428933|reactome:R-DME-2730905|reactome:R-DME-2871796|reactome:R-DME-2871809|reactome:R-DME-375165|reactome:R-DME-5654688|go:"GO:0008355"(olfactory learning)|reactome:R-DME-5654689|reactome:R-DME-5654693|reactome:R-DME-5654695|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654710|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5654720|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5673001|reactome:R-DME-6811558|reactome:R-DME-74749|reactome:R-DME-74751|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-9027284|reactome:R-DME-912631|reactome:R-DME-9607240|reactome:R-DME-983695|reactome:R-DME-5654733|dip:DIP-21223N refseq:NP_524119.2|flybase:FBgn0000414|ensemblmetazoa:FBgn0000414(gene)|ensemblmetazoa:FBtr0075318(transcript)|go:"GO:0005118"(sevenless binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007349"(cellularization)|go:"GO:0007391"(dorsal closure)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030424"(axon)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0045874"(positive regulation of sevenless signaling pathway)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098793"(presynapse)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028761|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-8856825|reactome:R-DME-8856828 pubmed:9671493(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:GNPfKX2LH0HRXEW4ASFDTrXN3VY7227 rogid:XcOuBhCV6ZOpIOxRpX/qWTa3Xp07227 intact-crc:973F668D9EAB955C|rigid:SImLMgJkKhUXZFNRyMJdrDVhNM0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q05201 uniprotkb:Q24027 intact:EBI-209758|uniprotkb:Q961V4|uniprotkb:Q9VMC1|ensemblmetazoa:FBpp0078964 intact:EBI-868965 psi-mi:eya_drome(display_long)|uniprotkb:eya(gene name)|psi-mi:eya(display_short)|uniprotkb:cli(gene name synonym)|uniprotkb:CG9554(orf name)|uniprotkb:Protein Clift(gene name synonym) psi-mi:q24027_drome(display_long)|uniprotkb:dac(gene name)|psi-mi:dac(display_short)|uniprotkb:CG4952(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872334 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523492.1|refseq:NP_723188.1|flybase:FBgn0000320|dip:DIP-19253N|ensemblmetazoa:FBgn0000320(gene)|ensemblmetazoa:FBtr0079335(transcript)|go:"GO:0001744"(insect visual primordium formation)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007419"(ventral cord development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008406"(gonad development)|go:"GO:0008584"(male gonad development)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030946"(protein tyrosine phosphatase activity, metal-dependent)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0070285"(pigment cell development)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR006545(EYA)|interpro:IPR028472|interpro:IPR038102|interpro:IPR042577 flybase:FBgn0005677|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007411"(axon guidance)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007483"(genital disc morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016319"(mushroom body development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035211"(spermathecum morphogenesis)|go:"GO:0035215"(genital disc development)|go:"GO:0035263"(genital disc sexually dimorphic development)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0043704"(photoreceptor cell fate specification)|go:"GO:0048098"(antennal joint development)|go:"GO:0048749"(compound eye development)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR037000 pubmed:9927595(see-also)|pubmed:9428513(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:owG+XSUY77mdV1nsAe7eILGxuho7227 rogid:B19RKBrARwDXMPK5S4ii0L2h+Gs7227 intact-crc:0B006DA1AC8594E5|rigid:ku031maqPCOaOkj17eDGjQFADtY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O61495 uniprotkb:Q24175 intact:EBI-868982 intact:EBI-128624|ensemblmetazoa:FBpp0073824 psi-mi:o61495_drome(display_long)|uniprotkb:nuf(gene name)|psi-mi:nuf(display_short)|uniprotkb:CG33991(orf name) psi-mi:q24175_drome(display_long)|uniprotkb:dah(gene name)|psi-mi:dah(display_short)|uniprotkb:Apd(gene name synonym)|uniprotkb:Dah(gene name synonym)|uniprotkb:Dmel\CG6157(gene name synonym)|uniprotkb:"fs(1)dah"(gene name synonym)|uniprotkb:Dmel_CG6157(orf name)|uniprotkb:CG6157(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872338 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0013718|go:"GO:0005813"(centrosome)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030496"(midbody)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0045179"(apical cortex)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR019018|interpro:IPR037245 refseq:NP_511162.1|flybase:FBgn0015926|ensemblmetazoa:FBgn0015926(gene)|ensemblmetazoa:FBtr0074007(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007349"(cellularization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR043145 pubmed:10444383(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:OnndNdOM36FJDJbp2Jlo38MY3RA7227 rogid:IIYG0wJu9SF227t5+d7Dux1TNn07227 intact-crc:D0AAB3BC4D43FF4C|rigid:Ll18EUfsYYbj9a3Z1DtR0YLp2zA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P27619 uniprotkb:O61618 intact:EBI-199421|uniprotkb:Q0KHS4|uniprotkb:Q9VXM2|ensemblmetazoa:FBpp0089277|ensemblmetazoa:FBpp0089280|ensemblmetazoa:FBpp0290809|ensemblmetazoa:FBpp0290810 intact:EBI-868990 psi-mi:dyn_drome(display_long)|uniprotkb:shi(gene name)|psi-mi:shi(display_short)|uniprotkb:CG18102(orf name)|uniprotkb:dDyn(gene name synonym)|uniprotkb:Protein shibire(gene name synonym) psi-mi:o61618_drome(display_long)|uniprotkb:Dap160(gene name)|psi-mi:Dap160(display_short)|uniprotkb:CG1099(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872342 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036278.1|refseq:NP_001036279.1|refseq:NP_001162766.1|refseq:NP_001162768.1|refseq:NP_524853.2|refseq:NP_727910.1|refseq:NP_727911.1|refseq:NP_996465.1|refseq:NP_996466.1|refseq:NP_996467.1|refseq:NP_996468.1|flybase:FBgn0003392|dip:DIP-17621N|ensemblmetazoa:FBgn0003392(gene)|ensemblmetazoa:FBtr0074123(transcript)|ensemblmetazoa:FBtr0074124(transcript)|ensemblmetazoa:FBtr0301594(transcript)|ensemblmetazoa:FBtr0301595(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007291"(sperm individualization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007349"(cellularization)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007637"(proboscis extension reflex)|go:"GO:0008017"(microtubule binding)|go:"GO:0008355"(olfactory learning)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030424"(axon)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0035152"(regulation of tube architecture, open tracheal system)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0040008"(regulation of growth)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045202"(synapse)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0061883"(clathrin-dependent endocytosis involved in vitellogenesis)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090148"(membrane fission)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:0150008"(bulk synaptic vesicle endocytosis)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|reactome:R-DME-190873|reactome:R-DME-196025|reactome:R-DME-3928665|reactome:R-DME-432720|reactome:R-DME-432722|reactome:R-DME-437239|reactome:R-DME-8856828 flybase:FBgn0023388|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008104"(protein localization)|go:"GO:0016197"(endosomal transport)|go:"GO:0045179"(apical cortex)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR036028 pubmed:9668096(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:1uT0LaH+gjGC9t6PDwrVJfYljBc7227 rogid:CDue2hjqJIqHmYa67wue1WtnfEg7227 intact-crc:CC40B9E5D67D8EB8|rigid:gInpNHjr9uDo42lA+1MMS7WggyA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07663 uniprotkb:O76324 intact:EBI-496170|uniprotkb:O17483|uniprotkb:O76882|uniprotkb:O76883|uniprotkb:O76884|uniprotkb:O76885|uniprotkb:Q24446|uniprotkb:Q24447|uniprotkb:Q24448|uniprotkb:Q24449|uniprotkb:Q6PVA3|uniprotkb:Q8MLY0|uniprotkb:Q9GN20|uniprotkb:Q9GN51|uniprotkb:Q9GQH9|uniprotkb:Q9GV48|uniprotkb:Q9GV53|uniprotkb:Q9GV54|uniprotkb:Q9GV55|uniprotkb:Q9W4X0|ensemblmetazoa:FBpp0070455 intact:EBI-189923|uniprotkb:A4V3P5|uniprotkb:Q0KHY4|uniprotkb:Q9V462|ensemblmetazoa:FBpp0085104|ensemblmetazoa:FBpp0085105|ensemblmetazoa:FBpp0085106|ensemblmetazoa:FBpp0306615|ensemblmetazoa:FBpp0422974 psi-mi:per_drome(display_long)|uniprotkb:Protein clock-6(gene name synonym)|uniprotkb:per(gene name)|psi-mi:per(display_short)|uniprotkb:CG2647(orf name) psi-mi:dco_drome(display_long)|uniprotkb:dco(gene name)|psi-mi:dco(display_short)|uniprotkb:dbt(gene name synonym)|uniprotkb:Protein double-time(gene name synonym)|uniprotkb:CG2048(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872346 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525056.2|flybase:FBgn0003068|refseq:NP_001259194.1|dip:DIP-29426N|ensemblmetazoa:FBgn0003068(gene)|ensemblmetazoa:FBtr0070477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001306"(age-dependent response to oxidative stress)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007616"(long-term memory)|go:"GO:0007617"(mating behavior)|go:"GO:0007619"(courtship behavior)|go:"GO:0007620"(copulation)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0044297"(cell body)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0048512"(circadian behavior)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR035965|rcsb pdb:1WA9|rcsb pdb:3GEC|rcsb pdb:3RTY|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432524|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 refseq:NP_524602.1|refseq:NP_733414.1|refseq:NP_733415.1|flybase:FBgn0002413|refseq:NP_001263132.1|dip:DIP-46048N|ensemblmetazoa:FBgn0002413(gene)|ensemblmetazoa:FBtr0085742(transcript)|ensemblmetazoa:FBtr0085743(transcript)|ensemblmetazoa:FBtr0085744(transcript)|ensemblmetazoa:FBtr0334548(transcript)|ensemblmetazoa:FBtr0473370(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007154"(cell communication)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007555"(regulation of ecdysteroid secretion)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-390023|reactome:R-DME-390150|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432524|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 pubmed:9674431(see-also)|pubmed:14701759(see-also)|pubmed:14759367(see-also)|pubmed:9674430(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+l/mg+2MJForY5dORYWnWsVAhNI7227 rogid:ei2gU3lKLNgH3s2sv4AHRE7OM8Q7227 intact-crc:9C1BE8F6EAA9266F|rigid:XTKpmBkRVvbHYup6RJgmkYbhzkY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24306 uniprotkb:O02002 intact:EBI-456419|uniprotkb:A4V1Z9|uniprotkb:Q0E8E4|uniprotkb:Q8MRM5|uniprotkb:Q9VUX5|uniprotkb:A9UN33|ensemblmetazoa:FBpp0075254|ensemblmetazoa:FBpp0075255|ensemblmetazoa:FBpp0075256|ensemblmetazoa:FBpp0305793|ensemblmetazoa:FBpp0305794|ensemblmetazoa:FBpp0305795 intact:EBI-167663|uniprotkb:Q9W1N0|ensemblmetazoa:FBpp0071971 psi-mi:diap1_drome(display_long)|uniprotkb:Diap1(gene name)|psi-mi:Diap1(display_short)|uniprotkb:Apoptosis 1 inhibitor(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase th(gene name synonym)|uniprotkb:Iap1(gene name synonym)|uniprotkb:Inhibitor of apoptosis 1(gene name synonym)|uniprotkb:Protein thread(gene name synonym)|uniprotkb:th(gene name synonym)|uniprotkb:CG12284(orf name)|uniprotkb:RING-type E3 ubiquitin transferase Diap1(gene name synonym) psi-mi:casp1_drome(display_long)|uniprotkb:Dcp-1(gene name)|psi-mi:Dcp-1(display_short)|uniprotkb:CG5370(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872350 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524101.2|refseq:NP_730097.1|refseq:NP_730098.1|flybase:FBgn0260635|refseq:NP_001261916.1|refseq:NP_001261917.1|refseq:NP_001261918.1|go:"GO:0006915"(apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0022416"(chaeta development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0045116"(protein neddylation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|ensemblmetazoa:FBgn0260635(gene)|ensemblmetazoa:FBtr0075499(transcript)|ensemblmetazoa:FBtr0075500(transcript)|ensemblmetazoa:FBtr0075501(transcript)|ensemblmetazoa:FBtr0333617(transcript)|ensemblmetazoa:FBtr0333618(transcript)|ensemblmetazoa:FBtr0333619(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|mint:Q24306|rcsb pdb:1JD4|rcsb pdb:1JD5|rcsb pdb:1JD6|rcsb pdb:1Q4Q|rcsb pdb:1SDZ|rcsb pdb:1SE0|rcsb pdb:3SIP|rcsb pdb:3SIQ|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-3769402|reactome:R-DME-390150|reactome:R-DME-5675482|reactome:R-DME-8948747|reactome:R-DME-8948751 refseq:NP_476974.1|flybase:FBgn0010501|ensemblmetazoa:FBgn0010501(gene)|ensemblmetazoa:FBtr0072062(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010623"(programmed cell death involved in cell development)|go:"GO:0012501"(programmed cell death)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045476"(nurse cell apoptotic process)|go:"GO:0048477"(oogenesis)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990525"(BIR domain binding)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139 pubmed:10077606(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:loBQ//cKQ1NYhq3gnIKwRBn5vZg7227 rogid:sY/9RuOQT/bsELp83N0Nfmekhgo7227 intact-crc:442A9CC045CDA500|rigid:SODydgd6t4aDWP+WScj3Oq3+aBk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O01382 uniprotkb:O02002 intact:EBI-91422|uniprotkb:Q9VAH1|ensemblmetazoa:FBpp0084848 intact:EBI-167663|uniprotkb:Q9W1N0|ensemblmetazoa:FBpp0071971 psi-mi:drice_drome(display_long)|uniprotkb:drICE(gene name synonym)|uniprotkb:CG7788(orf name)|uniprotkb:Drice(gene name)|psi-mi:Drice(display_short)|uniprotkb:ICE(gene name synonym) psi-mi:casp1_drome(display_long)|uniprotkb:Dcp-1(gene name)|psi-mi:Dcp-1(display_short)|uniprotkb:CG5370(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872354 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524551.2|flybase:FBgn0019972|ensemblmetazoa:FBgn0019972(gene)|ensemblmetazoa:FBtr0085482(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0010165"(response to X-ray)|go:"GO:0010623"(programmed cell death involved in cell development)|go:"GO:0012501"(programmed cell death)|go:"GO:0016322"(neuron remodeling)|go:"GO:0035070"(salivary gland histolysis)|go:"GO:0035103"(sterol regulatory element binding protein cleavage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045476"(nurse cell apoptotic process)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:1990525"(BIR domain binding)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|rcsb pdb:3SIP|rcsb pdb:3SIR|reactome:R-DME-111465|reactome:R-DME-264870|reactome:R-DME-75153|dip:DIP-21838N refseq:NP_476974.1|flybase:FBgn0010501|ensemblmetazoa:FBgn0010501(gene)|ensemblmetazoa:FBtr0072062(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010623"(programmed cell death involved in cell development)|go:"GO:0012501"(programmed cell death)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045476"(nurse cell apoptotic process)|go:"GO:0048477"(oogenesis)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990525"(BIR domain binding)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139 pubmed:10733594(see-also)|pubmed:9321398(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:aJREbCpkH2DICPbhBY7VVZe4qx07227 rogid:sY/9RuOQT/bsELp83N0Nfmekhgo7227 intact-crc:56D79D4F9E20258B|rigid:HpJkWyjat9fpfnC1EV7ow+UFrXs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O02002 uniprotkb:O02002 intact:EBI-167663|uniprotkb:Q9W1N0|ensemblmetazoa:FBpp0071971 intact:EBI-167663|uniprotkb:Q9W1N0|ensemblmetazoa:FBpp0071971 psi-mi:casp1_drome(display_long)|uniprotkb:Dcp-1(gene name)|psi-mi:Dcp-1(display_short)|uniprotkb:CG5370(orf name) psi-mi:casp1_drome(display_long)|uniprotkb:Dcp-1(gene name)|psi-mi:Dcp-1(display_short)|uniprotkb:CG5370(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872358 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476974.1|flybase:FBgn0010501|ensemblmetazoa:FBgn0010501(gene)|ensemblmetazoa:FBtr0072062(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010623"(programmed cell death involved in cell development)|go:"GO:0012501"(programmed cell death)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045476"(nurse cell apoptotic process)|go:"GO:0048477"(oogenesis)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990525"(BIR domain binding)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139 refseq:NP_476974.1|flybase:FBgn0010501|ensemblmetazoa:FBgn0010501(gene)|ensemblmetazoa:FBtr0072062(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010623"(programmed cell death involved in cell development)|go:"GO:0012501"(programmed cell death)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045476"(nurse cell apoptotic process)|go:"GO:0048477"(oogenesis)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990525"(BIR domain binding)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139 pubmed:10733594(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:sY/9RuOQT/bsELp83N0Nfmekhgo7227 rogid:sY/9RuOQT/bsELp83N0Nfmekhgo7227 intact-crc:613147BFC7D17765|rigid:KxFsFSFe2PTKvuShOE8wLfbrOGE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VLW8 uniprotkb:Q95YG3 intact:EBI-156415|ensemblmetazoa:FBpp0079112|ensemblmetazoa:FBpp0290544|ensemblmetazoa:FBpp0310061 intact:EBI-869007 psi-mi:q9vlw8_drome(display_long)|uniprotkb:r2d2(gene name)|psi-mi:r2d2(display_short)|uniprotkb:Dmel\CG7138(gene name synonym)|uniprotkb:R2D2(gene name synonym)|uniprotkb:R2d2(gene name synonym)|uniprotkb:cg7138(gene name synonym)|uniprotkb:CG7138(orf name)|uniprotkb:Dmel_CG7138(orf name) psi-mi:q95yg3_drome(display_long)|uniprotkb:Dcr-2(gene name)|psi-mi:Dcr-2(display_short)|uniprotkb:dcr-2(gene name synonym)|uniprotkb:CG6493(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872362 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162903.1|refseq:NP_609152.1|flybase:FBgn0031951|refseq:NP_001285720.1|dip:DIP-34805N|ensemblmetazoa:FBgn0031951(gene)|ensemblmetazoa:FBtr0079489(transcript)|ensemblmetazoa:FBtr0301329(transcript)|ensemblmetazoa:FBtr0343415(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016442"(RISC complex)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035197"(siRNA binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0070918"(primary sncRNA processing)|go:"GO:0070920"(regulation of production of small RNA involved in gene silencing by RNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|reactome:R-DME-203927|reactome:R-DME-426486 flybase:FBgn0034246|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0006342"|go:"GO:0007626"(locomotory behavior)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0009597"(detection of virus)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035197"(siRNA binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0098586"(cellular response to virus)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036389|interpro:IPR038248 pubmed:14512631(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xnR+vKJN0j+r0G/bo3UdrnNAjIU7227 rogid:IMwfObhQ1+W8CeMngvVKnraPnjo7227 intact-crc:B20FC0F925953BCB|rigid:a8E2EIIbR+FXbz+aFCQur6NVV7s false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q94527 uniprotkb:P98149 intact:EBI-869024|uniprotkb:Q9U435|uniprotkb:Q9U436|uniprotkb:Q9U437|uniprotkb:Q9U438|uniprotkb:Q9U439|uniprotkb:Q9U440|uniprotkb:Q9U6H3|uniprotkb:Q9U6H4|uniprotkb:Q9U6H5|uniprotkb:Q9VHI0|uniprotkb:A4V2K3|ensemblmetazoa:FBpp0088375|ensemblmetazoa:FBpp0088971|ensemblmetazoa:FBpp0088973 intact:EBI-188843|uniprotkb:Q1LYZ5|uniprotkb:Q8MT54|uniprotkb:Q9VJE2|ensemblmetazoa:FBpp0080561|ensemblmetazoa:FBpp0080562|ensemblmetazoa:FBpp0290793 psi-mi:nfkb1_drome(display_long)|uniprotkb:Relish protein(gene name synonym)|uniprotkb:Rel-p110(gene name synonym)|uniprotkb:Rel(gene name)|psi-mi:Rel(display_short)|uniprotkb:CG11992(orf name) psi-mi:dif_drome(display_long)|uniprotkb:Dif(gene name)|psi-mi:Dif(display_short)|uniprotkb:CG6794(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872366 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477094.1|refseq:NP_996187.1|refseq:NP_996188.1|refseq:NP_996189.1|flybase:FBgn0014018|dip:DIP-60434N|ensemblmetazoa:FBgn0014018(gene)|ensemblmetazoa:FBtr0089338(transcript)|ensemblmetazoa:FBtr0089339(transcript)|ensemblmetazoa:FBtr0089340(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0006964"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0006967"(positive regulation of antifungal peptide biosynthetic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051607"(defense response to virus)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:2000647"(negative regulation of stem cell proliferation)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209394|reactome:R-DME-209560|reactome:R-DME-214399|reactome:R-DME-214411|reactome:R-DME-214416|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-6798695|reactome:R-DME-9020702|reactome:R-DME-933542 refseq:NP_001162999.1|refseq:NP_523589.2|refseq:NP_724050.1|flybase:FBgn0011274|dip:DIP-34965N|ensemblmetazoa:FBgn0011274(gene)|ensemblmetazoa:FBtr0081008(transcript)|ensemblmetazoa:FBtr0081009(transcript)|ensemblmetazoa:FBtr0301578(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0034097"(response to cytokine)|go:"GO:0035070"(salivary gland histolysis)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011363(Dorsal protein)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-9020702|reactome:R-DME-933542 pubmed:10409696(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:QSjX/buJS65odmpaKMzPkTgHW/Y7227 rogid:LlE+/iR1xdrGI7Qg/QJiRJHNmL87227 intact-crc:0181CA2AD4E6D6E6|rigid:q58G1I13vwi04/br7ZjtNJLJxfw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9GYU8 uniprotkb:P98149 intact:EBI-161961|uniprotkb:Q9VG41|ensemblmetazoa:FBpp0082137 intact:EBI-188843|uniprotkb:Q1LYZ5|uniprotkb:Q8MT54|uniprotkb:Q9VJE2|ensemblmetazoa:FBpp0080561|ensemblmetazoa:FBpp0080562|ensemblmetazoa:FBpp0290793 psi-mi:nup88_drome(display_long)|uniprotkb:mbo(gene name)|psi-mi:mbo(display_short)|uniprotkb:Nup88(gene name synonym)|uniprotkb:Nucleoporin Nup88(gene name synonym)|uniprotkb:dNup88(gene name synonym)|uniprotkb:88 kDa nuclear pore complex protein(gene name synonym)|uniprotkb:Protein members only(gene name synonym)|uniprotkb:CG6819(orf name) psi-mi:dif_drome(display_long)|uniprotkb:Dif(gene name)|psi-mi:Dif(display_short)|uniprotkb:CG6794(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872370 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524330.2|flybase:FBgn0026207|ensemblmetazoa:FBgn0026207(gene)|ensemblmetazoa:FBtr0082668(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031981"(nuclear lumen)|go:"GO:0046826"(negative regulation of protein export from nucleus)|interpro:IPR019321|interpro:IPR037700|reactome:R-DME-159227|reactome:R-DME-159230|reactome:R-DME-159231|reactome:R-DME-159236|reactome:R-DME-3301854|reactome:R-DME-3371453|reactome:R-DME-4551638|reactome:R-DME-4615885|reactome:R-DME-5578749|dip:DIP-18195N refseq:NP_001162999.1|refseq:NP_523589.2|refseq:NP_724050.1|flybase:FBgn0011274|dip:DIP-34965N|ensemblmetazoa:FBgn0011274(gene)|ensemblmetazoa:FBtr0081008(transcript)|ensemblmetazoa:FBtr0081009(transcript)|ensemblmetazoa:FBtr0301578(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0034097"(response to cytokine)|go:"GO:0035070"(salivary gland histolysis)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011363(Dorsal protein)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-9020702|reactome:R-DME-933542 pubmed:10921908(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:a58sYPQ56KDVGtSnPUhqq/P9wnI7227 rogid:LlE+/iR1xdrGI7Qg/QJiRJHNmL87227 intact-crc:E154332F2AA7DC8B|rigid:wUoOgnLQwppYW1m7jay9KxMyPe4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P54359 uniprotkb:Q9NHV6 intact:EBI-188936|uniprotkb:Q24092|uniprotkb:Q9VDK8|ensemblmetazoa:FBpp0083352 intact:EBI-869079 psi-mi:sept2_drome(display_long)|uniprotkb:Sep2(gene name)|psi-mi:Sep2(display_short)|uniprotkb:CG4173(orf name) psi-mi:q9nhv6_drome(display_long)|uniprotkb:Dlip2(gene name)|psi-mi:Dlip2(display_short)|uniprotkb:Dip2(gene name synonym)|uniprotkb:CG9771(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872378 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524417.1|flybase:FBgn0014029|dip:DIP-20060N|ensemblmetazoa:FBgn0014029(gene)|ensemblmetazoa:FBtr0083945(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007295"(growth of a germarium-derived egg chamber)|go:"GO:0007349"(cellularization)|go:"GO:0007444"(imaginal disc development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379 flybase:FBgn0040466|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR006612(Zinc finger, C2CH-type) pubmed:11884525(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:yZOoGT0rH7z1Sm3rbziG/xiMNMg7227 rogid:aQiuGUhWRFekE9plrn3OYaAJpVU7227 intact-crc:651E8140B46403FC|rigid:Ronpy+nkleL1nrWtcJbj36yP9FE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42207 uniprotkb:Q9NHV6 intact:EBI-120528|uniprotkb:Q9VRH5|uniprotkb:Q8IQ47|ensemblmetazoa:FBpp0076897 intact:EBI-869079 psi-mi:sept1_drome(display_long)|uniprotkb:DIFF6 protein homolog(gene name synonym)|uniprotkb:Protein innocent bystander(gene name synonym)|uniprotkb:CG1403(orf name)|uniprotkb:Sep1(gene name)|psi-mi:Sep1(display_short)|uniprotkb:Diff6(gene name synonym)|uniprotkb:iby(gene name synonym) psi-mi:q9nhv6_drome(display_long)|uniprotkb:Dlip2(gene name)|psi-mi:Dlip2(display_short)|uniprotkb:Dip2(gene name synonym)|uniprotkb:CG9771(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872382 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0011710(gene)|ensemblmetazoa:FBtr0077198(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0007349"(cellularization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|refseq:NP_523430.1|flybase:FBgn0011710|dip:DIP-18454N flybase:FBgn0040466|go:"GO:0003677"(DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR006612(Zinc finger, C2CH-type) pubmed:11884525(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:owbyZvFu8+uF3t60BTm9IqquTL47227 rogid:aQiuGUhWRFekE9plrn3OYaAJpVU7227 intact-crc:C63471DB48ACD34F|rigid:qa1ccUv0kcpEIh/wJPVwLa+oK+0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P15330 uniprotkb:Q9NHV5 intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222 intact:EBI-869087 psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name) psi-mi:q9nhv5_drome(display_long)|uniprotkb:Dlip3(gene name)|psi-mi:Dlip3(display_short)|uniprotkb:Dip3(gene name synonym)|uniprotkb:CG12767(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872386 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542 flybase:FBgn0040465|go:"GO:0000228"(nuclear chromosome)|go:"GO:0001099"(basal RNA polymerase II transcription machinery binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006955"(immune response)|go:"GO:0007469"(antennal development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0016604"(nuclear body)|go:"GO:0042480"(negative regulation of eye photoreceptor cell development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045316"(negative regulation of compound eye photoreceptor development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004210(BESS motif)|interpro:IPR006578(MADF) pubmed:12459265(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227 rogid:FSyPy4rhKudaEzJr4biJQ0Qn6Rg7227 intact-crc:FF1020B5DB82552E|rigid:VuaQLivqIOJ1OkCGqTH+SekdKmg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9W0S9 uniprotkb:P23792 intact:EBI-94338|uniprotkb:Q9NGP2|ensemblmetazoa:FBpp0072420 intact:EBI-152064|uniprotkb:Q9VXJ4|uniprotkb:Q53YG0|ensemblmetazoa:FBpp0074028|ensemblmetazoa:FBpp0099796 psi-mi:dip2_drome(display_long)|uniprotkb:DIP2(gene name)|psi-mi:DIP2(display_short)|uniprotkb:CG7020(orf name) psi-mi:disc_drome(display_long)|uniprotkb:disco(gene name)|psi-mi:disco(display_short)|uniprotkb:CG9908(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872390 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612019.2|flybase:FBgn0024806|ensemblmetazoa:FBgn0024806(gene)|ensemblmetazoa:FBtr0072520(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR010506(DMAP1-binding)|interpro:IPR037337|interpro:IPR042099 refseq:NP_001033847.1|refseq:NP_523362.2|flybase:FBgn0000459|dip:DIP-19064N|ensemblmetazoa:FBgn0000459(gene)|ensemblmetazoa:FBtr0074250(transcript)|ensemblmetazoa:FBtr0100384(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007469"(antennal development)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007601"(visual perception)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050896"(response to stimulus)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR040436 pubmed:12137943(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:9SrSeyTwzVTtlOcKUTcC6i0ce2o7227 rogid:6Cbs780mLOjCMEnHepExeRvfu387227 intact-crc:3A641CA34B7F5A89|rigid:gW2kkrfJZIrZFb1Pic+lgFEG6uw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q02936 uniprotkb:Q9VNJ5 intact:EBI-499194|uniprotkb:A4V396|uniprotkb:Q9VCQ4|ensemblmetazoa:FBpp0099945 intact:EBI-869097|uniprotkb:Q8SY40|uniprotkb:Q9U477|uniprotkb:Q5U173|uniprotkb:B6IDI9|ensemblmetazoa:FBpp0078314 psi-mi:hh_drome(display_long)|uniprotkb:hh(gene name)|psi-mi:hh(display_short)|uniprotkb:CG4637(orf name) psi-mi:disp_drome(display_long)|uniprotkb:CG2019(orf name)|uniprotkb:disp(gene name)|psi-mi:disp(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872394 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034065.1|flybase:FBgn0004644|dip:DIP-51313N|ensemblmetazoa:FBgn0004644(gene)|ensemblmetazoa:FBtr0100506(transcript)|go:"GO:0001708"(cell fate specification)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002385"(mucosal immune response)|go:"GO:0005113"(patched binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007280"(pole cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007418"(ventral midline development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0007473"(wing disc proximal/distal pattern formation)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0007487"(analia development)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008347"(glial cell migration)|go:"GO:0008354"(germ cell migration)|go:"GO:0008544"(epidermis development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016015"(morphogen activity)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0035154"(terminal cell fate specification, open tracheal system)|go:"GO:0035215"(genital disc development)|go:"GO:0035217"(labial disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035231"(cytoneme assembly)|go:"GO:0035232"(germ cell attraction)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035288"(anterior head segmentation)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045168"(cell-cell signaling involved in cell fate commitment)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048099"(anterior/posterior lineage restriction, imaginal disc)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0060914"(heart formation)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR000320(Hedgehog amino-terminal signaling region)|interpro:IPR001657(Peptidase C46, hedgehog protein)|interpro:IPR001767(Peptidase C46, hedgehog protein, hint region)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR006141(Intein splicing site)|interpro:IPR009045(Hedgehog/DD-peptidase, zinc-binding motif)|interpro:IPR036844|rcsb pdb:1AT0|rcsb pdb:2IBG|rcsb pdb:6TD6|rcsb pdb:6TYY|reactome:R-DME-209338|reactome:R-DME-209471|reactome:R-DME-5358346|reactome:R-DME-5362798|reactome:R-DME-5632681 refseq:NP_524734.2|flybase:FBgn0029088|ensemblmetazoa:FBgn0029088(gene)|ensemblmetazoa:FBtr0078665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007225"(patched ligand maturation)|go:"GO:0007280"(pole cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035230"(cytoneme)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|interpro:IPR030223|rcsb pdb:6TBU|rcsb pdb:6TD6|reactome:R-DME-209471 pubmed:10619433(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:dXfS1AFla3efAqH2ITEHX65v0PQ7227 rogid:H/FYwrr0h55tsOn4Edz0QTqFUB47227 intact-crc:7D1DDD71A5013AD7|rigid:1mcgacN+szz4Dq1YWa0FgH2BB/U false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10627 uniprotkb:P15330 intact:EBI-104826|uniprotkb:Q8MT07|uniprotkb:Q8T8Y9|uniprotkb:Q9W1W1|uniprotkb:Q1LZ34|ensemblmetazoa:FBpp0071864|ensemblmetazoa:FBpp0099476|ensemblmetazoa:FBpp0311714 intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222 psi-mi:twist_drome(display_long)|uniprotkb:twi(gene name)|psi-mi:twi(display_short)|uniprotkb:CG2956(orf name) psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872398 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033967.1|refseq:NP_523816.2|flybase:FBgn0003900|refseq:NP_001286752.1|ensemblmetazoa:FBgn0003900(gene)|ensemblmetazoa:FBtr0071953(transcript)|ensemblmetazoa:FBtr0100130(transcript)|ensemblmetazoa:FBtr0345653(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0007507"(heart development)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032502"(developmental process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0055001"(muscle cell development)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015789(Twist)|interpro:IPR036638 refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542 pubmed:10660560(see-also)|pubmed:9154833(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:opc0LqFf1LFamPnLiKVnBlMgYzs7227 rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227 intact-crc:367590D4B01EA9D2|rigid:mmVz1mz5fUOv8FEY6QiwIi32qoU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P22812 uniprotkb:P15330 intact:EBI-93181|uniprotkb:Q9VN15|uniprotkb:B7Z0I9|uniprotkb:E8NH30|ensemblmetazoa:FBpp0291542 intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222 psi-mi:tube_drome(display_long)|uniprotkb:CG10520(orf name)|uniprotkb:tub(gene name)|psi-mi:tub(display_short)|uniprotkb:tube(gene name synonym) psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872402 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189164.1|flybase:FBgn0003882|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR029397|rcsb pdb:1D2Z|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874|go:"GO:0045087"(innate immune response)|ensemblmetazoa:FBgn0003882(gene)|ensemblmetazoa:FBtr0302338(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009620"(response to fungus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|dip:DIP-27623N refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542 pubmed:9405646(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:v00LZV72cvvYVI5cCthONXIlmrs7227 rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227 intact-crc:857D96C1B8B34CD5|rigid:P8fnt4KOtoogIT2UqNuEk9eWhus false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O97102 uniprotkb:P15330 intact:EBI-114439|ensemblmetazoa:FBpp0078984|ensemblmetazoa:FBpp0312327 intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222 psi-mi:o97102_drome(display_long)|uniprotkb:smt3(gene name)|psi-mi:smt3(display_short)|uniprotkb:Smt3(gene name synonym)|uniprotkb:DmSUMO-1(gene name synonym)|uniprotkb:Dm0342(gene name synonym)|uniprotkb:DmSmt3(gene name synonym)|uniprotkb:Dmel\CG4494(gene name synonym)|uniprotkb:Dmsmt3(gene name synonym)|uniprotkb:SMT3(gene name synonym)|uniprotkb:SUMO(gene name synonym)|uniprotkb:Sumo(gene name synonym)|uniprotkb:"anon-EST:Posey240"(gene name synonym)|uniprotkb:dSmt3(gene name synonym)|uniprotkb:dsmt3(gene name synonym)|uniprotkb:"l(2)04493"(gene name synonym)|uniprotkb:"l(2)SH0182"(gene name synonym)|uniprotkb:"l(2)SH2 0182"(gene name synonym)|uniprotkb:CG4494(orf name)|uniprotkb:sumo(gene name synonym)|uniprotkb:Dmel_CG4494(orf name) psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872406 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477411.1|go:"GO:0000940"(outer kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|ensemblmetazoa:FBgn0264922(gene)|ensemblmetazoa:FBtr0079356(transcript)|ensemblmetazoa:FBtr0346716(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016925"(protein sumoylation)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030496"(midbody)|go:"GO:0031386"(protein tag)|go:"GO:0035073"(pupariation)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:O97102|rcsb pdb:2K1F|reactome:R-DME-196791|reactome:R-DME-3065679|reactome:R-DME-3108214|reactome:R-DME-3232118|reactome:R-DME-3899300|reactome:R-DME-4090294|reactome:R-DME-4551638|reactome:R-DME-4570464|reactome:R-DME-4615885|reactome:R-DME-4755510|reactome:R-DME-5696395|refseq:NP_001303312.1|flybase:FBgn0264922 refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542 pubmed:11756545(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:fqo3Y86DDI0SsWGEfanaOs8qJlk7227 rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227 intact-crc:ED1F80330B716CBC|rigid:7ib1osv7X1uSSkgDWwL/qRk0zoA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q94527 uniprotkb:P15330 intact:EBI-869024|uniprotkb:Q9U435|uniprotkb:Q9U436|uniprotkb:Q9U437|uniprotkb:Q9U438|uniprotkb:Q9U439|uniprotkb:Q9U440|uniprotkb:Q9U6H3|uniprotkb:Q9U6H4|uniprotkb:Q9U6H5|uniprotkb:Q9VHI0|uniprotkb:A4V2K3|ensemblmetazoa:FBpp0088375|ensemblmetazoa:FBpp0088971|ensemblmetazoa:FBpp0088973 intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222 psi-mi:nfkb1_drome(display_long)|uniprotkb:Relish protein(gene name synonym)|uniprotkb:Rel-p110(gene name synonym)|uniprotkb:Rel(gene name)|psi-mi:Rel(display_short)|uniprotkb:CG11992(orf name) psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872410 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477094.1|refseq:NP_996187.1|refseq:NP_996188.1|refseq:NP_996189.1|flybase:FBgn0014018|dip:DIP-60434N|ensemblmetazoa:FBgn0014018(gene)|ensemblmetazoa:FBtr0089338(transcript)|ensemblmetazoa:FBtr0089339(transcript)|ensemblmetazoa:FBtr0089340(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0006964"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0006967"(positive regulation of antifungal peptide biosynthetic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051607"(defense response to virus)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:2000647"(negative regulation of stem cell proliferation)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209394|reactome:R-DME-209560|reactome:R-DME-214399|reactome:R-DME-214411|reactome:R-DME-214416|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-6798695|reactome:R-DME-9020702|reactome:R-DME-933542 refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542 pubmed:10409696(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:QSjX/buJS65odmpaKMzPkTgHW/Y7227 rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227 intact-crc:25F310D511D7A331|rigid:CKPmD1QUXbXprK3Sl7F02qD6Ya8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q05652 uniprotkb:P15330 intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005 intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222 psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short) psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872414 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542 pubmed:9405646(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227 rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227 intact-crc:E311D85D12B81A3E|rigid:6jELBMnCU4vGrngEHVgHKX5zAoM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P12370 uniprotkb:P15330 intact:EBI-82224|uniprotkb:Q9VL99|uniprotkb:A4V0I0|ensemblmetazoa:FBpp0079448|ensemblmetazoa:FBpp0089382|ensemblmetazoa:FBpp0307466 intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222 psi-mi:kapc1_drome(display_long)|uniprotkb:Pka-C1(gene name)|psi-mi:Pka-C1(display_short)|uniprotkb:CdkA(gene name synonym)|uniprotkb:DC0(gene name synonym)|uniprotkb:Protein kinase DC0(gene name synonym)|uniprotkb:CG4379(orf name) psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872418 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0000273(gene)|ensemblmetazoa:FBtr0079851(transcript)|ensemblmetazoa:FBtr0079852(transcript)|ensemblmetazoa:FBtr0335495(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007615"(anesthesia-resistant memory)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008355"(olfactory learning)|go:"GO:0008359"(regulation of bicoid mRNA localization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046823"(negative regulation of nucleocytoplasmic transport)|go:"GO:0048477"(oogenesis)|go:"GO:0048682"(sprouting of injured axon)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P12370|reactome:R-DME-163615|reactome:R-DME-164378|reactome:R-DME-180024|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209360|reactome:R-DME-381676|reactome:R-DME-392517|reactome:R-DME-432040|reactome:R-DME-4420097|reactome:R-DME-442720|reactome:R-DME-5578775|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5621575|reactome:R-DME-983231|refseq:NP_723479.1|refseq:NP_995672.1|flybase:FBgn0000273|refseq:NP_476977.1|dip:DIP-23727N refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542 pubmed:1325392(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:e7pEt3E/V/RB/nj6uqwtAs5u1js7227 rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227 intact-crc:3F2BABB942E049DF|rigid:AFN2QWmygq9Ul+aAvbdonMrPoyM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10041 uniprotkb:P29503 intact:EBI-115346|uniprotkb:Q6T3F7|uniprotkb:Q6T3G1|uniprotkb:Q6T3G7|uniprotkb:Q6T3G8|uniprotkb:Q6T3H0|uniprotkb:Q6T3H3|uniprotkb:Q6T3I3|uniprotkb:Q6T3I5|uniprotkb:Q6T3I7|uniprotkb:Q6T3J1|uniprotkb:Q6T3J2|uniprotkb:Q6T3J3|uniprotkb:Q6T3J4|uniprotkb:Q6T3K0|uniprotkb:Q6T3K1|uniprotkb:Q6T3K9|uniprotkb:Q6T3L5|uniprotkb:Q6T3L7|uniprotkb:Q6T3L9|uniprotkb:Q6T3M2|uniprotkb:Q6T3M4|uniprotkb:Q6T3M7|uniprotkb:Q6T3N1|uniprotkb:Q6T3N3|uniprotkb:Q6T3N5|uniprotkb:Q6T3N7|uniprotkb:Q6T4M9|uniprotkb:Q6T4N0|uniprotkb:Q6T4N1|uniprotkb:Q6T4N2|uniprotkb:Q6T4N3|uniprotkb:Q6T4N4|uniprotkb:Q6T4N6|uniprotkb:Q95RM9|uniprotkb:Q99108|uniprotkb:Q9VDY2|ensemblmetazoa:FBpp0083153|ensemblmetazoa:FBpp0083154|ensemblmetazoa:FBpp0293200 intact:EBI-197212|uniprotkb:Q26306|uniprotkb:Q27273|uniprotkb:Q8INP6|uniprotkb:Q8INP7|uniprotkb:Q960M1|ensemblmetazoa:FBpp0081481 psi-mi:dl_drome(display_long)|uniprotkb:Dl(gene name)|psi-mi:Dl(display_short)|uniprotkb:CG3619(orf name) psi-mi:neur_drome(display_long)|uniprotkb:neur(gene name)|psi-mi:neur(display_short)|uniprotkb:neu(gene name synonym)|uniprotkb:CG11988(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872422 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001247193.1|refseq:NP_477264.1|refseq:NP_732412.1|flybase:FBgn0000463|ensemblmetazoa:FBgn0000463(gene)|ensemblmetazoa:FBtr0083739(transcript)|ensemblmetazoa:FBtr0083740(transcript)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|ensemblmetazoa:FBtr0304658(transcript)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045466"(R7 cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|rcsb pdb:4XIB|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007475"(apposition of dorsal and ventral imaginal disc-derived wing surfaces)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0001708"(cell fate specification)|dip:DIP-22726N refseq:NP_001163563.1|refseq:NP_476652.1|refseq:NP_731309.1|refseq:NP_731310.1|refseq:NP_731311.1|flybase:FBgn0002932|dip:DIP-17176N|ensemblmetazoa:FBgn0002932(gene)|ensemblmetazoa:FBtr0082003(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0045314"(regulation of compound eye photoreceptor development)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046532"(regulation of photoreceptor cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048749"(compound eye development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR006573(NEUZ)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037962|interpro:IPR043136|mint:P29503|rcsb pdb:2YUE|rcsb pdb:4KG0 pubmed:11740942(see-also)|pubmed:11740940(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:2fMti94FA6yxkjlH7kgvKFV8gSM7227 rogid:XvbaN0Fg9K79x+Y56S19ovl/n5U7227 intact-crc:3DC4815951168E1B|rigid:aNbraasjE3odctsZk1Ll8gM4K4g false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O01368 uniprotkb:P15330 intact:EBI-868028 intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222 psi-mi:o01368_drome(display_long)|uniprotkb:nej(gene name)|psi-mi:nej(display_short)|uniprotkb:CG15319(orf name) psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872426 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261617|dip:DIP-41329N|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008347"(glial cell migration)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016573"(histone acetylation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0043971"(histone H3-K18 acetylation)|go:"GO:0043974"(histone H3-K27 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043993"("histone acetyltransferase activity (H3-K18 specific)")|go:"GO:0044017"("histone acetyltransferase activity (H3-K27 specific)")|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0098793"(presynapse)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR038547|interpro:IPR043145|mint:O01368 refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542 pubmed:10669739(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:JrQCBD9JpkCR4jgg0/08mthcy5o7227 rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227 intact-crc:D0E5865154A8FD00|rigid:x1POIUnZJAfooRI57rnteAwRkNk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07207 uniprotkb:P10041 intact:EBI-103438|uniprotkb:O97458|uniprotkb:P04154|uniprotkb:Q9W4T8|ensemblmetazoa:FBpp0070483|ensemblmetazoa:FBpp0293201 intact:EBI-115346|uniprotkb:Q6T3F7|uniprotkb:Q6T3G1|uniprotkb:Q6T3G7|uniprotkb:Q6T3G8|uniprotkb:Q6T3H0|uniprotkb:Q6T3H3|uniprotkb:Q6T3I3|uniprotkb:Q6T3I5|uniprotkb:Q6T3I7|uniprotkb:Q6T3J1|uniprotkb:Q6T3J2|uniprotkb:Q6T3J3|uniprotkb:Q6T3J4|uniprotkb:Q6T3K0|uniprotkb:Q6T3K1|uniprotkb:Q6T3K9|uniprotkb:Q6T3L5|uniprotkb:Q6T3L7|uniprotkb:Q6T3L9|uniprotkb:Q6T3M2|uniprotkb:Q6T3M4|uniprotkb:Q6T3M7|uniprotkb:Q6T3N1|uniprotkb:Q6T3N3|uniprotkb:Q6T3N5|uniprotkb:Q6T3N7|uniprotkb:Q6T4M9|uniprotkb:Q6T4N0|uniprotkb:Q6T4N1|uniprotkb:Q6T4N2|uniprotkb:Q6T4N3|uniprotkb:Q6T4N4|uniprotkb:Q6T4N6|uniprotkb:Q95RM9|uniprotkb:Q99108|uniprotkb:Q9VDY2|ensemblmetazoa:FBpp0083153|ensemblmetazoa:FBpp0083154|ensemblmetazoa:FBpp0293200 psi-mi:notch_drome(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:CG3936(orf name) psi-mi:dl_drome(display_long)|uniprotkb:Dl(gene name)|psi-mi:Dl(display_short)|uniprotkb:CG3619(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872430 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476859.2|flybase:FBgn0004647|ensemblmetazoa:FBgn0004647(gene)|ensemblmetazoa:FBtr0070507(transcript)|ensemblmetazoa:FBtr0304659(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002213"(defense response to insect)|go:"GO:0003682"(chromatin binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007391"(dorsal closure)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009608"(response to symbiont)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0022416"(chaeta development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0007498"(mesoderm development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0007616"(long-term memory)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0040008"(regulation of growth)|go:"GO:0042686"(regulation of cardioblast cell fate specification)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045316"(negative regulation of compound eye photoreceptor development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048627"(myoblast development)|go:"GO:0048664"(neuron fate determination)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050699"(WW domain binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0060289"(compartment boundary maintenance)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990433"(CSL-Notch-Mastermind transcription factor complex)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1OT8|rcsb pdb:2JMF|refseq:NP_001245510.1|dip:DIP-5N refseq:NP_001247193.1|refseq:NP_477264.1|refseq:NP_732412.1|flybase:FBgn0000463|ensemblmetazoa:FBgn0000463(gene)|ensemblmetazoa:FBtr0083739(transcript)|ensemblmetazoa:FBtr0083740(transcript)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|ensemblmetazoa:FBtr0304658(transcript)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045466"(R7 cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|rcsb pdb:4XIB|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007475"(apposition of dorsal and ventral imaginal disc-derived wing surfaces)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0001708"(cell fate specification)|dip:DIP-22726N pubmed:1657403(see-also)|pubmed:2185893(see-also)|pubmed:9778511(see-also)|pubmed:10862754(see-also)|pubmed:10504334(see-also)|pubmed:1618155(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:T1iHJGMHXkhxbFRybmSDlizN7oQ7227 rogid:2fMti94FA6yxkjlH7kgvKFV8gSM7227 intact-crc:B3EAA5FD04057CA6|rigid:PIo2x6TYU0AJ8rdQecSONE5alDo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9GYU8 uniprotkb:P15330 intact:EBI-161961|uniprotkb:Q9VG41|ensemblmetazoa:FBpp0082137 intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222 psi-mi:nup88_drome(display_long)|uniprotkb:mbo(gene name)|psi-mi:mbo(display_short)|uniprotkb:Nup88(gene name synonym)|uniprotkb:Nucleoporin Nup88(gene name synonym)|uniprotkb:dNup88(gene name synonym)|uniprotkb:88 kDa nuclear pore complex protein(gene name synonym)|uniprotkb:Protein members only(gene name synonym)|uniprotkb:CG6819(orf name) psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872434 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524330.2|flybase:FBgn0026207|ensemblmetazoa:FBgn0026207(gene)|ensemblmetazoa:FBtr0082668(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031981"(nuclear lumen)|go:"GO:0046826"(negative regulation of protein export from nucleus)|interpro:IPR019321|interpro:IPR037700|reactome:R-DME-159227|reactome:R-DME-159230|reactome:R-DME-159231|reactome:R-DME-159236|reactome:R-DME-3301854|reactome:R-DME-3371453|reactome:R-DME-4551638|reactome:R-DME-4615885|reactome:R-DME-5578749|dip:DIP-18195N refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542 pubmed:10921908(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:a58sYPQ56KDVGtSnPUhqq/P9wnI7227 rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227 intact-crc:C526E9D0EF96A95C|rigid:Fm9jV+PQ0ja8fgS8re3M5JvuaSo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KNM2 uniprotkb:P15330 intact:EBI-74966|intact:EBI-1627711|ensemblmetazoa:FBpp0077741|ensemblmetazoa:FBpp0077742|ensemblmetazoa:FBpp0301731|ensemblmetazoa:FBpp0301732 intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222 psi-mi:q7knm2_drome(display_long)|uniprotkb:lwr(gene name)|psi-mi:lwr(display_short)|uniprotkb:semi(gene name synonym)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:DUbc9(gene name synonym)|uniprotkb:DmUbc9(gene name synonym)|uniprotkb:Dmel\CG3018(gene name synonym)|uniprotkb:Dmubc9(gene name synonym)|uniprotkb:FBgn0010602(gene name synonym)|uniprotkb:Iwr(gene name synonym)|uniprotkb:Lwr(gene name synonym)|uniprotkb:Ubc 9(gene name synonym)|uniprotkb:Ubc-9(gene name synonym)|uniprotkb:UbcD9(gene name synonym)|uniprotkb:dUBC9(gene name synonym)|uniprotkb:dUbc9(gene name synonym)|uniprotkb:dip4(gene name synonym)|uniprotkb:hbl(gene name synonym)|uniprotkb:i105(gene name synonym)|uniprotkb:i56(gene name synonym)|uniprotkb:"l(2)01519"(gene name synonym)|uniprotkb:"l(2)02858"(gene name synonym)|uniprotkb:"l(2)05486"(gene name synonym)|uniprotkb:"l(2)05487"(gene name synonym)|uniprotkb:ubc9(gene name synonym)|uniprotkb:Dmel_CG3018(orf name)|uniprotkb:UBC9(gene name synonym)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:CG3018(orf name) psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872438 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476978.1|refseq:NP_722637.1|flybase:FBgn0010602|refseq:NP_001259833.1|refseq:NP_001259834.1|ensemblmetazoa:FBgn0010602(gene)|ensemblmetazoa:FBtr0078081(transcript)|ensemblmetazoa:FBtr0078082(transcript)|ensemblmetazoa:FBtr0310028(transcript)|ensemblmetazoa:FBtr0310029(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000940"(outer kinetochore)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007391"(dorsal closure)|go:"GO:0008354"(germ cell migration)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030721"(spectrosome organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033134"(ubiquitin activating enzyme binding)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0035207"(negative regulation of hemocyte proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0140540"(negative regulation melanotic encapsulation of foreign target)|go:"GO:1904677"(positive regulation of somatic stem cell division)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-196791|reactome:R-DME-3108214|reactome:R-DME-3232118|reactome:R-DME-3899300|reactome:R-DME-4090294|reactome:R-DME-4551638|reactome:R-DME-4570464|reactome:R-DME-4615885|reactome:R-DME-4755510|reactome:R-DME-5696395 refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542 pubmed:10660560(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:0klFCJX3ACVlfPFXyh4vl9degjM7227 rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227 intact-crc:81D59835E5A7C66E|rigid:SHFoMOP43O2Mv6FRzKBq6oJ+vWQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q94902 uniprotkb:P10041 intact:EBI-869108 intact:EBI-115346|uniprotkb:Q6T3F7|uniprotkb:Q6T3G1|uniprotkb:Q6T3G7|uniprotkb:Q6T3G8|uniprotkb:Q6T3H0|uniprotkb:Q6T3H3|uniprotkb:Q6T3I3|uniprotkb:Q6T3I5|uniprotkb:Q6T3I7|uniprotkb:Q6T3J1|uniprotkb:Q6T3J2|uniprotkb:Q6T3J3|uniprotkb:Q6T3J4|uniprotkb:Q6T3K0|uniprotkb:Q6T3K1|uniprotkb:Q6T3K9|uniprotkb:Q6T3L5|uniprotkb:Q6T3L7|uniprotkb:Q6T3L9|uniprotkb:Q6T3M2|uniprotkb:Q6T3M4|uniprotkb:Q6T3M7|uniprotkb:Q6T3N1|uniprotkb:Q6T3N3|uniprotkb:Q6T3N5|uniprotkb:Q6T3N7|uniprotkb:Q6T4M9|uniprotkb:Q6T4N0|uniprotkb:Q6T4N1|uniprotkb:Q6T4N2|uniprotkb:Q6T4N3|uniprotkb:Q6T4N4|uniprotkb:Q6T4N6|uniprotkb:Q95RM9|uniprotkb:Q99108|uniprotkb:Q9VDY2|ensemblmetazoa:FBpp0083153|ensemblmetazoa:FBpp0083154|ensemblmetazoa:FBpp0293200 psi-mi:q94902_drome(display_long)|uniprotkb:kuz(gene name)|psi-mi:kuz(display_short)|uniprotkb:CG7147(orf name) psi-mi:dl_drome(display_long)|uniprotkb:Dl(gene name)|psi-mi:Dl(display_short)|uniprotkb:CG3619(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872442 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0259984|go:"GO:0003007"(heart morphogenesis)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0008347"(glial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0035051"(cardiocyte differentiation)|go:"GO:0035386"(regulation of Roundabout signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0098595"(perivitelline space)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR024079|interpro:IPR034025|interpro:IPR036436 refseq:NP_001247193.1|refseq:NP_477264.1|refseq:NP_732412.1|flybase:FBgn0000463|ensemblmetazoa:FBgn0000463(gene)|ensemblmetazoa:FBtr0083739(transcript)|ensemblmetazoa:FBtr0083740(transcript)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|ensemblmetazoa:FBtr0304658(transcript)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045466"(R7 cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|rcsb pdb:4XIB|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007475"(apposition of dorsal and ventral imaginal disc-derived wing surfaces)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0001708"(cell fate specification)|dip:DIP-22726N pubmed:12591935(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:grwh/VZudq+kFSrdfeWejjN5xlo7227 rogid:2fMti94FA6yxkjlH7kgvKFV8gSM7227 intact-crc:96B925B02E98E994|rigid:I3oPr0GArwL8MxG0YUM419Q+DGY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8T069 uniprotkb:P15330 intact:EBI-499943|ensemblmetazoa:FBpp0084679 intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222 psi-mi:q8t069_drome(display_long)|uniprotkb:CG9995(orf name)|uniprotkb:htt(gene name)|psi-mi:htt(display_short)|uniprotkb:huntingtin(gene name synonym) psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872446 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0027655|ensemblmetazoa:FBgn0027655(gene)|ensemblmetazoa:FBtr0085310(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0043005"(neuron projection)|go:"GO:0048489"(synaptic vesicle transport)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028426 refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542 pubmed:12379151(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:hfp8Vanylq24vtoLFM8vt/z2dXk7227 rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227 intact-crc:F80855D195019678|rigid:ASJ67n39noKKxYbDCSlbkno9SLA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16371 uniprotkb:P15330 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222 psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872450 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542 pubmed:9367978(see-also)|pubmed:9774673(see-also)|pubmed:10660305(see-also)|pubmed:8001118(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227 intact-crc:14A245951D49DE98|rigid:tcfozdEGZcVkxMISigDRkZDE9qs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P15330 uniprotkb:P15330 intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222 intact:EBI-198375|uniprotkb:O77088|uniprotkb:Q0E8P9|uniprotkb:Q6AWP3|uniprotkb:Q9VJD9|uniprotkb:Q9VJE0|ensemblmetazoa:FBpp0080560|ensemblmetazoa:FBpp0309222 psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name) psi-mi:dors_drome(display_long)|uniprotkb:dl(gene name)|psi-mi:dl(display_short)|uniprotkb:CG6667(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872454 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542 refseq:NP_001286014.1|refseq:NP_001163000.1|refseq:NP_001163001.1|refseq:NP_724052.1|refseq:NP_724053.1|refseq:NP_724054.1|flybase:FBgn0260632|dip:DIP-17423N|ensemblmetazoa:FBgn0260632(gene)|ensemblmetazoa:FBtr0081007(transcript)|ensemblmetazoa:FBtr0340250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034097"(response to cytokine)|go:"GO:0035006"(melanization defense response)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045612"(positive regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0070379"(high mobility group box 1 binding)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209400|reactome:R-DME-209406|reactome:R-DME-209560|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214869|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-4755510|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-9020702|reactome:R-DME-933542 pubmed:8202491(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227 rogid:NFjUIuH+t9TZGcAOMpUIz/e8aCQ7227 intact-crc:25AFFE593555D9DF|rigid:aVV6xmDs/ELOo35wwEbUQvTh6B0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24312 uniprotkb:Q94524 intact:EBI-208642|uniprotkb:A4V3R8|uniprotkb:Q59E73|uniprotkb:Q59E74|uniprotkb:Q59E75|uniprotkb:Q59E76|uniprotkb:Q59E77|uniprotkb:Q8SXJ1|uniprotkb:Q9NF76|uniprotkb:Q9W5G8|uniprotkb:Q9W5G9|intact:EBI-3428964|ensemblmetazoa:FBpp0088457|ensemblmetazoa:FBpp0100032 intact:EBI-158251|ensemblmetazoa:FBpp0082996|intact:EBI-1630760|uniprotkb:Q9VE95 psi-mi:ewg_drome(display_long)|uniprotkb:ewg(gene name)|psi-mi:ewg(display_short)|uniprotkb:CG3114(orf name)|uniprotkb:Protein erect wing(gene name synonym) psi-mi:dylt_drome(display_long)|uniprotkb:Dlc90F(gene name)|psi-mi:Dlc90F(display_short)|uniprotkb:Tctex(gene name synonym)|uniprotkb:CG12363(orf name)|uniprotkb:TCTEX-1 protein homolog(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872458 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0005427|refseq:NP_001014707.1|refseq:NP_001014708.1|refseq:NP_001014709.1|refseq:NP_001014710.1|refseq:NP_001014711.1|refseq:NP_001014712.1|refseq:NP_476892.4|refseq:NP_726660.3|ensemblmetazoa:FBgn0005427(gene)|ensemblmetazoa:FBtr0089442(transcript)|ensemblmetazoa:FBtr0100577(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007527"(adult somatic muscle development)|go:"GO:0007560"(imaginal disc morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR019525|interpro:IPR019526|interpro:IPR039142 go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007286"(spermatid development)|ensemblmetazoa:FBgn0024432(gene)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030286"(dynein complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|rcsb pdb:1YGT|rcsb pdb:2PG1|ensemblmetazoa:FBtr0083575(transcript)|rcsb pdb:3FM7|reactome:R-DME-6798695|refseq:NP_477356.1|flybase:FBgn0024432|dip:DIP-17339N pubmed:11069771(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:29G77Np5rNzj91nulmnnrjrPBYk7227 rogid:hMehJpmM08K6vCn+PxlZA2upMCs7227 intact-crc:D82C211508E188E8|rigid:sP3xFeEu28Sls7kjFVpBQOzHz0g false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O45030 uniprotkb:P31007 intact:EBI-869122|ensemblmetazoa:FBpp0087647 intact:EBI-389374|uniprotkb:Q7KV38|uniprotkb:Q7KV39|uniprotkb:Q7KV40|uniprotkb:Q7YXH8|uniprotkb:Q8SY37|uniprotkb:Q8T0C6|uniprotkb:Q95TF5|uniprotkb:Q9VYZ4|uniprotkb:Q9VYZ5|uniprotkb:Q9VYZ6|uniprotkb:A4V4A8|uniprotkb:A4V4B0|uniprotkb:A8JUR9|uniprotkb:A8JUS0|uniprotkb:C7LAH6|intact:EBI-3430803|ensemblmetazoa:FBpp0089351 psi-mi:o45030_drome(display_long)|uniprotkb:Vang(gene name)|psi-mi:Vang(display_short)|uniprotkb:stbm(gene name synonym)|uniprotkb:CG8075(orf name) psi-mi:dlg1_drome(display_long)|uniprotkb:dlg1(gene name)|psi-mi:dlg1(display_short)|uniprotkb:"l(1)dlg1"(gene name synonym)|uniprotkb:CG1725(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872462 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0015838|dip:DIP-35779N|ensemblmetazoa:FBgn0015838(gene)|ensemblmetazoa:FBtr0088566(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005109"(frizzled binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR009539(Strabismus)|reactome:R-DME-350368|reactome:R-DME-350376|reactome:R-DME-350379|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-450728 refseq:NP_001245623.1|refseq:NP_001096955.1|refseq:NP_001096956.1|refseq:NP_001162719.1|refseq:NP_511120.2|refseq:NP_727518.1|refseq:NP_727519.1|refseq:NP_727520.1|refseq:NP_996402.1|refseq:NP_996403.1|refseq:NP_996404.1|refseq:NP_996405.1|refseq:NP_996406.1|refseq:NP_996407.1|flybase:FBgn0001624|refseq:NP_001259447.1|go:"GO:0007399"(nervous system development)|go:"GO:0007617"(mating behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008104"(protein localization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016336"(establishment or maintenance of polarity of larval imaginal disc epithelium)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030054"(cell junction)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042332"(gravitaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046956"(positive phototaxis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0060581"(cell fate commitment involved in pattern specification)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:3TVT|rcsb pdb:4RP3|rcsb pdb:4RP4|rcsb pdb:4RP5|reactome:R-DME-438066|reactome:R-DME-451308|reactome:R-DME-6794361|reactome:R-DME-8849932|ensemblmetazoa:FBgn0001624(gene)|ensemblmetazoa:FBtr0073488(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0005920"(smooth septate junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007391"(dorsal closure)|dip:DIP-31531N pubmed:14562058(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KK7iFNVimizORrJxiz5fcSV2f8c7227 rogid:NSQ2GlnRFSHOn1DErzrCGZaeSz47227 intact-crc:2205A334A5F80B2F|rigid:7BaOWTAeQ4+uHqS+cOcAMvOGcUo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08510 uniprotkb:P31007 intact:EBI-85074|uniprotkb:A4V4Q2|uniprotkb:P08511|uniprotkb:P08512|uniprotkb:P08513|uniprotkb:Q24277|uniprotkb:Q24521|uniprotkb:Q7KUW5|uniprotkb:Q8IQY9|uniprotkb:Q8MT41|uniprotkb:Q9VWZ5|uniprotkb:Q9VWZ9|uniprotkb:Q9VX00|ensemblmetazoa:FBpp0088599|uniprotkb:B6IDJ2|uniprotkb:M9MSC0|uniprotkb:M9NEM4|uniprotkb:M9PF21 intact:EBI-389374|uniprotkb:Q7KV38|uniprotkb:Q7KV39|uniprotkb:Q7KV40|uniprotkb:Q7YXH8|uniprotkb:Q8SY37|uniprotkb:Q8T0C6|uniprotkb:Q95TF5|uniprotkb:Q9VYZ4|uniprotkb:Q9VYZ5|uniprotkb:Q9VYZ6|uniprotkb:A4V4A8|uniprotkb:A4V4B0|uniprotkb:A8JUR9|uniprotkb:A8JUS0|uniprotkb:C7LAH6|intact:EBI-3430803|ensemblmetazoa:FBpp0089351 psi-mi:kcnas_drome(display_long)|uniprotkb:Sh(gene name)|psi-mi:Sh(display_short)|uniprotkb:mns(gene name synonym)|uniprotkb:Protein minisleep(gene name synonym)|uniprotkb:CG12348(orf name) psi-mi:dlg1_drome(display_long)|uniprotkb:dlg1(gene name)|psi-mi:dlg1(display_short)|uniprotkb:"l(1)dlg1"(gene name synonym)|uniprotkb:CG1725(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872466 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162788.1|refseq:NP_001188668.1|refseq:NP_523393.3|refseq:NP_728120.1|refseq:NP_728122.1|refseq:NP_728123.1|refseq:NP_728124.1|refseq:NP_996497.1|ensemblmetazoa:FBgn0003380(gene)|ensemblmetazoa:FBtr0089657(transcript)|go:"GO:0001508"(action potential)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007611"(learning or memory)|go:"GO:0007619"(courtship behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0009584"(detection of visible light)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030431"(sleep)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0048047"(mating behavior, sex discrimination)|go:"GO:0007637"(proboscis extension reflex)|go:"GO:0048150"(behavioral response to ether)|go:"GO:0048675"(axon extension)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060025"(regulation of synaptic activity)|go:"GO:0071805"(potassium ion transmembrane transport)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:1HO2|rcsb pdb:1HO7|reactome:R-DME-1296072|go:"GO:1903351"(cellular response to dopamine)|refseq:NP_001259665.2|refseq:NP_996498.2|flybase:FBgn0003380|refseq:NP_001245727.1|dip:DIP-41151N refseq:NP_001245623.1|refseq:NP_001096955.1|refseq:NP_001096956.1|refseq:NP_001162719.1|refseq:NP_511120.2|refseq:NP_727518.1|refseq:NP_727519.1|refseq:NP_727520.1|refseq:NP_996402.1|refseq:NP_996403.1|refseq:NP_996404.1|refseq:NP_996405.1|refseq:NP_996406.1|refseq:NP_996407.1|flybase:FBgn0001624|refseq:NP_001259447.1|go:"GO:0007399"(nervous system development)|go:"GO:0007617"(mating behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008104"(protein localization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016336"(establishment or maintenance of polarity of larval imaginal disc epithelium)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030054"(cell junction)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042332"(gravitaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046956"(positive phototaxis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0060581"(cell fate commitment involved in pattern specification)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:3TVT|rcsb pdb:4RP3|rcsb pdb:4RP4|rcsb pdb:4RP5|reactome:R-DME-438066|reactome:R-DME-451308|reactome:R-DME-6794361|reactome:R-DME-8849932|ensemblmetazoa:FBgn0001624(gene)|ensemblmetazoa:FBtr0073488(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0005920"(smooth septate junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007391"(dorsal closure)|dip:DIP-31531N pubmed:9390515(see-also)|pubmed:8987744(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:fEBHWlsCdztu/LP5Ecu0vdPDEVQ7227 rogid:NSQ2GlnRFSHOn1DErzrCGZaeSz47227 intact-crc:3A0F87FE98A6C410|rigid:ZtOdkSBeH8ufRJag7xNsv1AfpA0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9NFR7 uniprotkb:P31007 intact:EBI-497189 intact:EBI-389374|uniprotkb:Q7KV38|uniprotkb:Q7KV39|uniprotkb:Q7KV40|uniprotkb:Q7YXH8|uniprotkb:Q8SY37|uniprotkb:Q8T0C6|uniprotkb:Q95TF5|uniprotkb:Q9VYZ4|uniprotkb:Q9VYZ5|uniprotkb:Q9VYZ6|uniprotkb:A4V4A8|uniprotkb:A4V4B0|uniprotkb:A8JUR9|uniprotkb:A8JUS0|uniprotkb:C7LAH6|intact:EBI-3430803|ensemblmetazoa:FBpp0089351 psi-mi:q9nfr7_drome(display_long)|uniprotkb:pins(gene name)|psi-mi:pins(display_short)|uniprotkb:raps(gene name synonym)|uniprotkb:CG5692(orf name) psi-mi:dlg1_drome(display_long)|uniprotkb:dlg1(gene name)|psi-mi:dlg1(display_short)|uniprotkb:"l(1)dlg1"(gene name synonym)|uniprotkb:CG1725(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872470 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0040080|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0055059"(asymmetric neuroblast division)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 refseq:NP_001245623.1|refseq:NP_001096955.1|refseq:NP_001096956.1|refseq:NP_001162719.1|refseq:NP_511120.2|refseq:NP_727518.1|refseq:NP_727519.1|refseq:NP_727520.1|refseq:NP_996402.1|refseq:NP_996403.1|refseq:NP_996404.1|refseq:NP_996405.1|refseq:NP_996406.1|refseq:NP_996407.1|flybase:FBgn0001624|refseq:NP_001259447.1|go:"GO:0007399"(nervous system development)|go:"GO:0007617"(mating behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008104"(protein localization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016336"(establishment or maintenance of polarity of larval imaginal disc epithelium)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030054"(cell junction)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042332"(gravitaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046956"(positive phototaxis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0060581"(cell fate commitment involved in pattern specification)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:3TVT|rcsb pdb:4RP3|rcsb pdb:4RP4|rcsb pdb:4RP5|reactome:R-DME-438066|reactome:R-DME-451308|reactome:R-DME-6794361|reactome:R-DME-8849932|ensemblmetazoa:FBgn0001624(gene)|ensemblmetazoa:FBtr0073488(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0005920"(smooth septate junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007391"(dorsal closure)|dip:DIP-31531N pubmed:11509184(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:bJLhIKptzMvBzyui3OKrX5Ey3sw7227 rogid:NSQ2GlnRFSHOn1DErzrCGZaeSz47227 intact-crc:71C660F1DB3E2ECB|rigid:peZIdjq0h/rMFkcR7GLJ2IAMxE4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P34082 uniprotkb:P31007 intact:EBI-868243|uniprotkb:P34083|uniprotkb:Q8IRS5|uniprotkb:Q9W4M6|uniprotkb:Q6IDE4|ensemblmetazoa:FBpp0070633 intact:EBI-389374|uniprotkb:Q7KV38|uniprotkb:Q7KV39|uniprotkb:Q7KV40|uniprotkb:Q7YXH8|uniprotkb:Q8SY37|uniprotkb:Q8T0C6|uniprotkb:Q95TF5|uniprotkb:Q9VYZ4|uniprotkb:Q9VYZ5|uniprotkb:Q9VYZ6|uniprotkb:A4V4A8|uniprotkb:A4V4B0|uniprotkb:A8JUR9|uniprotkb:A8JUS0|uniprotkb:C7LAH6|intact:EBI-3430803|ensemblmetazoa:FBpp0089351 psi-mi:fas2_drome(display_long)|uniprotkb:Fasciclin II(gene name synonym)|uniprotkb:Fas2(gene name)|psi-mi:Fas2(display_short)|uniprotkb:CG3665(orf name) psi-mi:dlg1_drome(display_long)|uniprotkb:dlg1(gene name)|psi-mi:dlg1(display_short)|uniprotkb:"l(1)dlg1"(gene name synonym)|uniprotkb:CG1725(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872478 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_726911.1|refseq:NP_726912.1|flybase:FBgn0000635|refseq:NP_525066.1|ensemblmetazoa:FBgn0000635(gene)|ensemblmetazoa:FBtr0070665(transcript)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008038"(neuron recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008355"(olfactory learning)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035158"(regulation of tube diameter, open tracheal system)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050808"(synapse organization)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0072553"(terminal button organization)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904800"(negative regulation of neuron remodeling)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009138(Neural cell adhesion)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179 refseq:NP_001245623.1|refseq:NP_001096955.1|refseq:NP_001096956.1|refseq:NP_001162719.1|refseq:NP_511120.2|refseq:NP_727518.1|refseq:NP_727519.1|refseq:NP_727520.1|refseq:NP_996402.1|refseq:NP_996403.1|refseq:NP_996404.1|refseq:NP_996405.1|refseq:NP_996406.1|refseq:NP_996407.1|flybase:FBgn0001624|refseq:NP_001259447.1|go:"GO:0007399"(nervous system development)|go:"GO:0007617"(mating behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008104"(protein localization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016336"(establishment or maintenance of polarity of larval imaginal disc epithelium)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030054"(cell junction)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042332"(gravitaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046956"(positive phototaxis)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0060581"(cell fate commitment involved in pattern specification)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:3TVT|rcsb pdb:4RP3|rcsb pdb:4RP4|rcsb pdb:4RP5|reactome:R-DME-438066|reactome:R-DME-451308|reactome:R-DME-6794361|reactome:R-DME-8849932|ensemblmetazoa:FBgn0001624(gene)|ensemblmetazoa:FBtr0073488(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0005920"(smooth septate junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007391"(dorsal closure)|dip:DIP-31531N pubmed:9390515(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:QW5g1dqazQzsvEKXYHT1dPOJNjU7227 rogid:NSQ2GlnRFSHOn1DErzrCGZaeSz47227 intact-crc:140B682EAC50D45B|rigid:A77hmfIV3435pn+beRXVJs9Pth8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40427 uniprotkb:P20009 intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515 intact:EBI-200556|uniprotkb:Q7KVF4|uniprotkb:Q8MZ41|uniprotkb:Q9W0Z8|uniprotkb:Q9W0Z9|intact:EBI-200569|ensemblmetazoa:FBpp0072286 psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name) psi-mi:dll_drome(display_long)|uniprotkb:Dll(gene name)|psi-mi:Dll(display_short)|uniprotkb:CG3629(orf name)|uniprotkb:Protein brista(gene name synonym)|uniprotkb:Ba(gene name synonym)|uniprotkb:BR(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872482 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N refseq:NP_523857.1|refseq:NP_726486.1|flybase:FBgn0000157|ensemblmetazoa:FBgn0000157(gene)|ensemblmetazoa:FBtr0072379(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007449"(proximal/distal pattern formation, imaginal disc)|go:"GO:0007469"(antennal development)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007485"(imaginal disc-derived male genitalia development)|go:"GO:0007487"(analia development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016319"(mushroom body development)|go:"GO:0035114"(imaginal disc-derived appendage morphogenesis)|go:"GO:0035215"(genital disc development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048264"(determination of ventral identity)|go:"GO:0048728"(proboscis development)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0010092"(specification of animal organ identity) pubmed:9671305(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227 rogid:QdJq1ENCqUK0Lucl0CTEi6bW7xc7227 intact-crc:89DB4FC7B8B08967|rigid:0MqPXeeE+QOXMr7pm824dfUnPww false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q94887 uniprotkb:Q8T626 intact:EBI-140638|uniprotkb:Q9VTU5|ensemblmetazoa:FBpp0075730 intact:EBI-424300|uniprotkb:Q8T627|uniprotkb:Q9W084|ensemblmetazoa:FBpp0072673 psi-mi:nrx4_drome(display_long)|uniprotkb:Nrx-IV(gene name)|psi-mi:Nrx-IV(display_short)|uniprotkb:CG6827(orf name)|uniprotkb:Neurexin IV(gene name synonym)|uniprotkb:Nrx(gene name synonym) psi-mi:dlt_drome(display_long)|uniprotkb:Protein vanaso(gene name synonym)|uniprotkb:Codanin 1 homolog(gene name synonym)|uniprotkb:dlt(gene name)|psi-mi:dlt(display_short)|uniprotkb:VA(gene name synonym)|uniprotkb:CG32315(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872486 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0013997(gene)|ensemblmetazoa:FBtr0075998(transcript)|go:"GO:0003015"(heart process)|go:"GO:0005886"(plasma membrane)|go:"GO:0005919"(pleated septate junction)|go:"GO:0007391"(dorsal closure)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0008104"(protein localization)|go:"GO:0008366"(axon ensheathment)|go:"GO:0016021"(integral component of membrane)|refseq:NP_524034.2|flybase:FBgn0013997|go:"GO:0019991"(septate junction assembly)|go:"GO:0021682"(nerve maturation)|go:"GO:0035151"(regulation of tube size, open tracheal system)|go:"GO:0045202"(synapse)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0061343"(cell adhesion involved in heart morphogenesis)|go:"GO:0072553"(terminal button organization)|go:"GO:0097105"(presynaptic membrane assembly)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup) refseq:NP_728672.1|flybase:FBgn0024510|ensemblmetazoa:FBgn0024510(gene)|ensemblmetazoa:FBtr0072790(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005737"(cytoplasm)|go:"GO:0007560"(imaginal disc morphogenesis)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR028171|interpro:IPR040031|dip:DIP-22407N pubmed:10102271(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:kSDCNYBENTCaLMtF6r5slY5bVAU7227 rogid:XbkVY7EHTI+LVCWesMz/abFkq+M7227 intact-crc:3FEDC0BE15C513E6|rigid:5oL358nXSdx71JI07Oz3J6+lUqE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P91664 uniprotkb:Q9W4S7 intact:EBI-193577|uniprotkb:Q1LZ15|uniprotkb:Q8SXE2|uniprotkb:Q95S07|ensemblmetazoa:FBpp0074785|ensemblmetazoa:FBpp0301959|ensemblmetazoa:FBpp0311541 intact:EBI-120162|intact:EBI-1629093|uniprotkb:O96903|uniprotkb:P91665|ensemblmetazoa:FBpp0070501|ensemblmetazoa:FBpp0303995 psi-mi:max_drome(display_long)|uniprotkb:Max(gene name)|psi-mi:Max(display_short)|uniprotkb:CG9648(orf name)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:myc_drome(display_long)|uniprotkb:Myc(gene name)|psi-mi:Myc(display_short)|uniprotkb:Diminutive protein(gene name synonym)|uniprotkb:dMyc1(gene name synonym)|uniprotkb:dm(gene name synonym)|uniprotkb:CG10798(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872490 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001246833.1|refseq:NP_649097.1|flybase:FBgn0017578|refseq:NP_001287114.1|dip:DIP-60982N|ensemblmetazoa:FBgn0017578(gene)|ensemblmetazoa:FBtr0075018(transcript)|ensemblmetazoa:FBtr0310276(transcript)|ensemblmetazoa:FBtr0345391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|reactome:R-DME-8953750 refseq:NP_525062.2|flybase:FBgn0262656|ensemblmetazoa:FBgn0262656(gene)|ensemblmetazoa:FBtr0070525(transcript)|ensemblmetazoa:FBtr0331605(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0017126"(nucleologenesis)|go:"GO:0022008"(neurogenesis)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042594"(response to starvation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0090062"(regulation of trehalose metabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-DME-8866911|refseq:NP_001259204.1|dip:DIP-18847N pubmed:8929412(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8emwPxqInArcDRnGhwlfFDi47t07227 rogid:7ytdhcO8e5nJXpbfE0Wa/FsJ4hA7227 intact-crc:03F7615CE3154192|rigid:vslfY4RBzk353aLjzkjzc3lyZQ0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9W4X9 uniprotkb:Q7K2D2 intact:EBI-165891|ensemblmetazoa:FBpp0070425 intact:EBI-132258|ensemblmetazoa:FBpp0087722 psi-mi:zw10_drome(display_long)|uniprotkb:Zw10(gene name)|psi-mi:Zw10(display_short)|uniprotkb:Mitotic 15 protein(gene name synonym)|uniprotkb:"mit(1)15"(gene name synonym)|uniprotkb:CG9900(orf name) psi-mi:dctn2_drome(display_long)|uniprotkb:DCTN2-p50(gene name)|psi-mi:DCTN2-p50(display_short)|uniprotkb:Dmn(gene name synonym)|uniprotkb:Dynactin 2 p50 subunit(gene name synonym)|uniprotkb:CG8269(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872494 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0004643(gene)|ensemblmetazoa:FBtr0070441(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007107"(membrane addition at site of cytokinesis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0031267"(small GTPase binding)|go:"GO:0036063"(acroblast)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0051233"(spindle midzone)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|reactome:R-DME-6811434|refseq:NP_524901.2|flybase:FBgn0004643 refseq:NP_524690.1|flybase:FBgn0021825|ensemblmetazoa:FBgn0021825(gene)|ensemblmetazoa:FBtr0088641(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005869"(dynactin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007602"(phototransduction)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0016020"(membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030286"(dynein complex)|go:"GO:0031982"(vesicle)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0048477"(oogenesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0061883"(clathrin-dependent endocytosis involved in vitellogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001019"(positive regulation of retrograde axon cargo transport)|interpro:IPR028133|reactome:R-DME-3371497|reactome:R-DME-6807878|reactome:R-DME-6811436 pubmed:9700164(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:2g70SyEE4RbzkGOfTrZEG603PT87227 rogid:c6gFayijPTgtdrPD989rylpHA787227 intact-crc:D84916F3CE0BB61D|rigid:sP6f3Lx6nygWqNkgbLzntNVLDus false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P22813 uniprotkb:Q24133 intact:EBI-130048|uniprotkb:Q9V8C1|ensemblmetazoa:FBpp0085961 intact:EBI-87640|uniprotkb:Q9VRP0|ensemblmetazoa:FBpp0076829|ensemblmetazoa:FBpp0076830 psi-mi:hsf_drome(display_long)|uniprotkb:Hsf(gene name)|psi-mi:Hsf(display_short)|uniprotkb:CG5748(orf name)|uniprotkb:Heat shock transcription factor(gene name synonym) psi-mi:dnaj1_drome(display_long)|uniprotkb:DnaJ-1(gene name)|psi-mi:DnaJ-1(display_short)|uniprotkb:DROJ1(gene name synonym)|uniprotkb:CG10578(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872498 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476575.1|flybase:FBgn0001222|ensemblmetazoa:FBgn0001222(gene)|ensemblmetazoa:FBtr0086782(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009408"(response to heat)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050832"(defense response to fungus)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1HKS|rcsb pdb:1HKT|reactome:R-DME-3371453|reactome:R-DME-3371511|reactome:R-DME-3371568|reactome:R-DME-3371571|dip:DIP-20041N refseq:NP_523936.2|refseq:NP_729086.1|ensemblmetazoa:FBgn0263106(gene)|ensemblmetazoa:FBtr0077123(transcript)|ensemblmetazoa:FBtr0077124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009408"(response to heat)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|flybase:FBgn0263106|dip:DIP-18469N pubmed:11157756(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xliYPBKMVWUtd+/gAbMtbunTDrk7227 rogid:a9IH3J+QRKijRMBTudpvE5YV/Ek7227 intact-crc:D2C3E0201AB71E3B|rigid:pDW3x/373TbZnIV5YeM3cQQhK1k false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P02828 uniprotkb:P26019 intact:EBI-136814|ensemblmetazoa:FBpp0072904|ensemblmetazoa:FBpp0305095|uniprotkb:P92174|uniprotkb:P92202|uniprotkb:Q9VZT3 intact:EBI-419315|ensemblmetazoa:FBpp0083514|uniprotkb:O77034|uniprotkb:Q8T992|uniprotkb:Q9VD90 psi-mi:hsp83_drome(display_long)|uniprotkb:Hsp83(gene name)|psi-mi:Hsp83(display_short)|uniprotkb:Hsp82(gene name synonym)|uniprotkb:HSP 82(gene name synonym)|uniprotkb:Hsp90(gene name synonym)|uniprotkb:CG1242(orf name) psi-mi:dpola_drome(display_long)|uniprotkb:PolA1(gene name)|psi-mi:PolA1(display_short)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:DNApol-alpha(gene name synonym)|uniprotkb:DNApol-alpha180(gene name synonym)|uniprotkb:POLA(gene name synonym)|uniprotkb:CG6349(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872502 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005158"(insulin receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|ensemblmetazoa:FBgn0001233(gene)|ensemblmetazoa:FBtr0073040(transcript)|ensemblmetazoa:FBtr0332873(transcript)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0009631"(cold acclimation)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0030911"(TPR domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0101031"(chaperone complex)|go:"GO:0106161"(obsolete positive regulation of small RNA loading onto RISC)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|reactome:R-DME-1227986|reactome:R-DME-1474151|reactome:R-DME-2029482|reactome:R-DME-203615|reactome:R-DME-3371497|reactome:R-DME-3371511|refseq:NP_523899.1|flybase:FBgn0001233|refseq:NP_001261362.1|go:"GO:0043248"(proteasome assembly)|dip:DIP-17366N|reactome:R-DME-399954|reactome:R-DME-5218920|reactome:R-DME-5675482|reactome:R-DME-6798695|reactome:R-DME-3371571|reactome:R-DME-8863795|reactome:R-DME-8937144|reactome:R-DME-8939211|reactome:R-DME-9009391|reactome:R-DME-9013418|reactome:R-DME-9652282 ensemblmetazoa:FBgn0259113(gene)|ensemblmetazoa:FBtr0084115(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0016895"(exodeoxyribonuclease activity, producing 5'-phosphomonoesters)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|go:"GO:0006273"(lagging strand elongation)|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|interpro:IPR043502|reactome:R-DME-113501|reactome:R-DME-68952|reactome:R-DME-68962|reactome:R-DME-69091|reactome:R-DME-69166|reactome:R-DME-69183|refseq:NP_536736.2|flybase:FBgn0259113|dip:DIP-23937N pubmed:6409898(see-also)|pubmed:11493638(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:PS2fd2RD7YWygzaMqF40SNCb2xQ7227 rogid:n2+VCQ0AbVsPB8iHlCvGYM17t7g7227 intact-crc:5739DD4CD14C8508|rigid:nqo9Cf4pTygzUIndcJ46nn3UcnU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:A1Z6M6 uniprotkb:P26019 intact:EBI-117913|ensemblmetazoa:FBpp0085479|ensemblmetazoa:FBpp0307645|uniprotkb:Q6NMU5 intact:EBI-419315|ensemblmetazoa:FBpp0083514|uniprotkb:O77034|uniprotkb:Q8T992|uniprotkb:Q9VD90 psi-mi:ttc4_drome(display_long)|uniprotkb:Dpit47(gene name)|psi-mi:Dpit47(display_short)|uniprotkb:Tetratricopeptide repeat protein 4 homolog(gene name synonym)|uniprotkb:CG3189(orf name) psi-mi:dpola_drome(display_long)|uniprotkb:PolA1(gene name)|psi-mi:PolA1(display_short)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:DNApol-alpha(gene name synonym)|uniprotkb:DNApol-alpha180(gene name synonym)|uniprotkb:POLA(gene name synonym)|uniprotkb:CG6349(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872506 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0266518(gene)|ensemblmetazoa:FBtr0086146(transcript)|ensemblmetazoa:FBtr0336664(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044059|refseq:NP_525106.2|refseq:NP_001260729.1|flybase:FBgn0266518 ensemblmetazoa:FBgn0259113(gene)|ensemblmetazoa:FBtr0084115(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0016895"(exodeoxyribonuclease activity, producing 5'-phosphomonoesters)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|go:"GO:0006273"(lagging strand elongation)|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|interpro:IPR043502|reactome:R-DME-113501|reactome:R-DME-68952|reactome:R-DME-68962|reactome:R-DME-69091|reactome:R-DME-69166|reactome:R-DME-69183|refseq:NP_536736.2|flybase:FBgn0259113|dip:DIP-23937N pubmed:11493638(see-also)|pubmed:9784499(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:IGOpxGXDVNzgZlssqRhENIOfObw7227 rogid:n2+VCQ0AbVsPB8iHlCvGYM17t7g7227 intact-crc:D2B46064927E932A|rigid:qd1X+lRf8qvEKWr7UKoUedMndwQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q27607 uniprotkb:Q9VJV8 intact:EBI-122256|uniprotkb:Q8T4E6|uniprotkb:Q94906|uniprotkb:Q9V442|uniprotkb:B5RIX0|ensemblmetazoa:FBpp0080148 intact:EBI-852898|intact:EBI-3410137|uniprotkb:O02005|uniprotkb:Q9NKE7|ensemblmetazoa:FBpp0099758 psi-mi:dpog1_drome(display_long)|uniprotkb:tam(gene name)|psi-mi:tam(display_short)|uniprotkb:MtPolA(gene name synonym)|uniprotkb:Polg(gene name synonym)|uniprotkb:Mitochondrial DNA polymerase catalytic subunit(gene name synonym)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:DNApol-gamma(gene name synonym)|uniprotkb:DNApol-gamma125(gene name synonym)|uniprotkb:DNApolG1(gene name synonym)|uniprotkb:"l(2)34Dc"(gene name synonym)|uniprotkb:"l(2)br5"(gene name synonym)|uniprotkb:pol gamma-alpha(gene name synonym)|uniprotkb:CG8987(orf name) psi-mi:dpog2_drome(display_long)|uniprotkb:DNApol-gamma35(gene name)|psi-mi:DNApol-gamma35(display_short)|uniprotkb:MtPolB(gene name synonym)|uniprotkb:DNA polymerase beta subunit(gene name synonym)|uniprotkb:DNA polymerase gamma 35kD subunit(gene name synonym)|uniprotkb:DNApol-gamma(gene name synonym)|uniprotkb:DNApolG2(gene name synonym)|uniprotkb:"l(2)34De"(gene name synonym)|uniprotkb:"l(2)br16"(gene name synonym)|uniprotkb:pol gamma-beta(gene name synonym)|uniprotkb:CG33650(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872510 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476821.1|flybase:FBgn0004406|ensemblmetazoa:FBgn0004406(gene)|ensemblmetazoa:FBtr0080571(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030382"(sperm mitochondrion organization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045004"(DNA replication proofreading)|interpro:IPR001098(DNA-directed DNA polymerase, family A)|interpro:IPR002297(DNA-directed DNA-polymerase, family A, mitochondria)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR019760|interpro:IPR041336|interpro:IPR043502 flybase:FBgn0004407|refseq:NP_001027262.1|ensemblmetazoa:FBgn0004407(gene)|ensemblmetazoa:FBtr0091627(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0071667"(DNA/RNA hybrid binding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR004154(Anticodon-binding)|interpro:IPR027030|interpro:IPR027031|interpro:IPR036621|interpro:IPR042064 pubmed:3095323(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2019/11/15 rogid:lLFGFcc54iOgeRigPeL20pnGJzU7227 rogid:+Sk/9XXfLWoO6kgu2o5bMbFBzK47227 intact-crc:B2A356DD12A8C25E|rigid:CunVzypfLvSkbLCe+RLKcBfNWyY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P49762 uniprotkb:P49762 intact:EBI-198460|intact:EBI-1628787|uniprotkb:Q8IMM0|uniprotkb:Q8T041|uniprotkb:Q95RC9|uniprotkb:Q9VAR8|ensemblmetazoa:FBpp0289021 intact:EBI-198460|intact:EBI-1628787|uniprotkb:Q8IMM0|uniprotkb:Q8T041|uniprotkb:Q95RC9|uniprotkb:Q9VAR8|ensemblmetazoa:FBpp0289021 psi-mi:doa_drome(display_long)|uniprotkb:Doa(gene name)|psi-mi:Doa(display_short)|uniprotkb:Protein darkener of apricot(gene name synonym)|uniprotkb:CG42320(orf name) psi-mi:doa_drome(display_long)|uniprotkb:Doa(gene name)|psi-mi:Doa(display_short)|uniprotkb:Protein darkener of apricot(gene name synonym)|uniprotkb:CG42320(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872514 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014679.1|refseq:NP_001014680.1|refseq:NP_001036765.1|refseq:NP_001138120.1|refseq:NP_001138121.1|flybase:FBgn0265998|refseq:NP_001014682.1|refseq:NP_001138122.1|ensemblmetazoa:FBgn0265998(gene)|ensemblmetazoa:FBtr0299743(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007399"(nervous system development)|go:"GO:0007548"(sex differentiation)|go:"GO:0007601"(visual perception)|go:"GO:0009306"(protein secretion)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0018993"(somatic sex determination)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048749"(compound eye development)|go:"GO:0050896"(response to stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) refseq:NP_001014679.1|refseq:NP_001014680.1|refseq:NP_001036765.1|refseq:NP_001138120.1|refseq:NP_001138121.1|flybase:FBgn0265998|refseq:NP_001014682.1|refseq:NP_001138122.1|ensemblmetazoa:FBgn0265998(gene)|ensemblmetazoa:FBtr0299743(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007399"(nervous system development)|go:"GO:0007548"(sex differentiation)|go:"GO:0007601"(visual perception)|go:"GO:0009306"(protein secretion)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0018993"(somatic sex determination)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048749"(compound eye development)|go:"GO:0050896"(response to stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) pubmed:7926721(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6q2TXb52pJh/W+ZpdE5q9Catl/o7227 rogid:6q2TXb52pJh/W+ZpdE5q9Catl/o7227 intact-crc:74FA1F51AACFE634|rigid:rTP7saLMFuTU0NUAGlNMQQAAArE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KV88 uniprotkb:Q24218 intact:EBI-868359|ensemblmetazoa:FBpp0089311|ensemblmetazoa:FBpp0089312 intact:EBI-74727 psi-mi:q7kv88_drome(display_long)|uniprotkb:CG16973-RD(gene name synonym)|uniprotkb:CG16973(orf name)|uniprotkb:msn(gene name)|psi-mi:msn(display_short)|uniprotkb:6286(gene name synonym)|uniprotkb:DMSN(gene name synonym)|uniprotkb:Dmel\CG16973(gene name synonym)|uniprotkb:HGK(gene name synonym)|uniprotkb:JNKKKK(gene name synonym)|uniprotkb:MESR5(gene name synonym)|uniprotkb:MSN(gene name synonym)|uniprotkb:Msn(gene name synonym)|uniprotkb:NIK(gene name synonym)|uniprotkb:Nik(gene name synonym)|uniprotkb:"l(3)03349"(gene name synonym)|uniprotkb:"l(3)06946"(gene name synonym)|uniprotkb:"l(3)6286"(gene name synonym)|uniprotkb:"l(3)j1E2"(gene name synonym)|uniprotkb:msm(gene name synonym)|uniprotkb:Dmel_CG16973(orf name) psi-mi:q24218_drome(display_long)|uniprotkb:dock(gene name)|psi-mi:dock(display_short)|uniprotkb:CG3727(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872522 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_995972.1|refseq:NP_995973.1|flybase:FBgn0010909|ensemblmetazoa:FBtr0072958(transcript)|ensemblmetazoa:FBtr0072959(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001748"(insect visual primordium development)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007097"(nuclear migration)|go:"GO:0007254"(JNK cascade)|go:"GO:0007391"(dorsal closure)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009611"(response to wounding)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042656"(JUN kinase kinase kinase kinase activity)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR021160|ensemblmetazoa:FBgn0010909(gene) flybase:FBgn0010583|go:"GO:0005158"(insulin receptor binding)|go:"GO:0007411"(axon guidance)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR036028|interpro:IPR036860 pubmed:10595512(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:rcJvSCSw3DtAy5Tu69AYlOm0O6c7227 rogid:1/0GiSNvZrkPK4ZFhlLHLZZ8DmE7227 intact-crc:B2ADB55CFED015DF|rigid:AmeZBW4fijKuecHXlUr7yp0Wy2U false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09208 uniprotkb:Q24218 intact:EBI-92063|uniprotkb:Q24023|uniprotkb:Q24089|uniprotkb:Q9VD94|uniprotkb:B7Z0N6|ensemblmetazoa:FBpp0083519|ensemblmetazoa:FBpp0288669|ensemblmetazoa:FBpp0288670|ensemblmetazoa:FBpp0288671 intact:EBI-74727 psi-mi:insr_drome(display_long)|uniprotkb:InR(gene name)|psi-mi:InR(display_short)|uniprotkb:dinr(gene name synonym)|uniprotkb:Dir-a(gene name synonym)|uniprotkb:Inr-a(gene name synonym)|uniprotkb:dIRH(gene name synonym)|uniprotkb:CG18402(orf name) psi-mi:q24218_drome(display_long)|uniprotkb:dock(gene name)|psi-mi:dock(display_short)|uniprotkb:CG3727(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872526 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138093.1|refseq:NP_001138094.1|refseq:NP_001138095.1|refseq:NP_524436.2|flybase:FBgn0283499|go:"GO:0007411"(axon guidance)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008585"(female gonad development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034059"(response to anoxia)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042321"(negative regulation of circadian sleep/wake cycle, sleep)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043559"(insulin binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0048542"(lymph gland development)|go:"GO:0048589"(developmental growth)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060180"(female mating behavior)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0061964"(negative regulation of entry into reproductive diapause)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070346"(positive regulation of fat cell proliferation)|go:"GO:0090278"(negative regulation of peptide hormone secretion)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904801"(positive regulation of neuron remodeling)|go:"GO:2000252"(negative regulation of feeding behavior)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|interpro:IPR036941|reactome:R-DME-110478|reactome:R-DME-77387|reactome:R-DME-9009391|ensemblmetazoa:FBgn0283499(gene)|ensemblmetazoa:FBtr0084121(transcript)|ensemblmetazoa:FBtr0290230(transcript)|ensemblmetazoa:FBtr0290231(transcript)|ensemblmetazoa:FBtr0290232(transcript)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005009"(insulin-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005899"(insulin receptor complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007285"(primary spermatocyte growth)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007399"(nervous system development) flybase:FBgn0010583|go:"GO:0005158"(insulin receptor binding)|go:"GO:0007411"(axon guidance)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR036028|interpro:IPR036860 pubmed:12702880(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:IS/+aD6emSortrv0wVSEn2MIlLw7227 rogid:1/0GiSNvZrkPK4ZFhlLHLZZ8DmE7227 intact-crc:0D32FD293D237263|rigid:qGPzplw2p/BfTUY4j/CJS6bofQE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O96525 uniprotkb:Q9VWE0 intact:EBI-869141 intact:EBI-119639|ensemblmetazoa:FBpp0074525 psi-mi:o96525_drome(display_long)|uniprotkb:upd1(gene name)|psi-mi:upd1(display_short)|uniprotkb:os(gene name synonym)|uniprotkb:unpaired(gene name synonym)|uniprotkb:CG5993(orf name) psi-mi:dome_drome(display_long)|uniprotkb:dome(gene name)|psi-mi:dome(display_short)|uniprotkb:CG14226(orf name)|uniprotkb:Protein domeless(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872530 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0004956|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003383"(apical constriction)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007538"(primary sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0007616"(long-term memory)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017145"(stem cell division)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0038001"(paracrine signaling)|go:"GO:0045177"(apical part of cell)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0060031"(mediolateral intercalation)|go:"GO:0060729"(intestinal epithelial structure maintenance)|interpro:IPR031901|reactome:R-DME-209209|reactome:R-DME-209228|reactome:R-DME-210688 refseq:NP_523412.1|flybase:FBgn0043903|ensemblmetazoa:FBgn0043903(gene)|ensemblmetazoa:FBtr0074756(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007616"(long-term memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0042246"(tissue regeneration)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0097678"(SOCS family protein binding)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|reactome:R-DME-209209|reactome:R-DME-209228|reactome:R-DME-210688|reactome:R-DME-6798695|dip:DIP-19869N pubmed:10879541(see-also)|pubmed:11825879(see-also)|pubmed:9784499(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Ml42xVRLQw5OzuFjcsDyElNHKz47227 rogid:dV9rgiRCyY1HVyUM804JDMtTBuo7227 intact-crc:F6AD3DA8C499B898|rigid:kJXgbhDQqryi7P0716jxT5cf/io false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24318 uniprotkb:Q27368 intact:EBI-530830|uniprotkb:O17472|uniprotkb:O44080|uniprotkb:Q86PE0|uniprotkb:Q8ML56|uniprotkb:Q9V6M0|uniprotkb:B8A3X4|ensemblmetazoa:FBpp0086853 intact:EBI-108384|uniprotkb:O77035|uniprotkb:Q5U0Z6|ensemblmetazoa:FBpp0083516|ensemblmetazoa:FBpp0083517|ensemblmetazoa:FBpp0083518|ensemblmetazoa:FBpp0311985 psi-mi:tfdp_drome(display_long)|uniprotkb:Dp(gene name)|psi-mi:Dp(display_short)|uniprotkb:CG4654(orf name) psi-mi:e2f1_drome(display_long)|uniprotkb:E2f1(gene name)|psi-mi:E2f1(display_short)|uniprotkb:E2f(gene name synonym)|uniprotkb:dE2F(gene name synonym)|uniprotkb:CG6376(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872538 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477039.1|refseq:NP_725267.1|flybase:FBgn0011763|ensemblmetazoa:FBgn0011763(gene)|ensemblmetazoa:FBtr0087740(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007113"(endomitotic cell cycle)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0031523"(Myb complex)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0045850"(positive regulation of nurse cell apoptotic process)|go:"GO:0048477"(oogenesis)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|reactome:R-DME-1538133|reactome:R-DME-2173796|reactome:R-DME-69231|reactome:R-DME-8953750|go:"GO:0045476"(nurse cell apoptotic process) refseq:NP_524437.2|refseq:NP_732646.1|refseq:NP_732647.1|flybase:FBgn0011766|refseq:NP_001287455.1|dip:DIP-21076N|ensemblmetazoa:FBgn0011766(gene)|ensemblmetazoa:FBtr0084117(transcript)|ensemblmetazoa:FBtr0084118(transcript)|ensemblmetazoa:FBtr0084119(transcript)|ensemblmetazoa:FBtr0346157(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0007419"(ventral cord development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045850"(positive regulation of nurse cell apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900117"(regulation of execution phase of apoptosis)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|reactome:R-DME-68689|reactome:R-DME-68911|reactome:R-DME-8953750 pubmed:11511545(see-also)|pubmed:8022787(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:uM/3Ia2BNTAfz62QpZVgh+S63NM7227 rogid:iuWAVrB7ugwrZPPrJbYLNhkvS2A7227 intact-crc:48B0943C5A1EBE36|rigid:DzIzlVJuKIQ/Bk5XObytNz0cZaU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VK34 uniprotkb:Q26263 intact:EBI-83837|ensemblmetazoa:FBpp0080015|intact:EBI-869173|uniprotkb:D5SHQ6|uniprotkb:O96505 intact:EBI-144502|uniprotkb:Q9V384|ensemblmetazoa:FBpp0087879 psi-mi:sirt1_drome(display_long)|uniprotkb:Sirt1(gene name)|psi-mi:Sirt1(display_short)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Sir2(gene name synonym)|uniprotkb:CG5216(orf name) psi-mi:dpn_drome(display_long)|uniprotkb:dpn(gene name)|psi-mi:dpn(display_short)|uniprotkb:CG8704(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872550 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0024291(gene)|ensemblmetazoa:FBtr0080434(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016740"(transferase activity)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046872"(metal ion binding)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:1901416"(regulation of response to ethanol)|go:"GO:2000253"(positive regulation of feeding behavior)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|reactome:R-DME-9617629|refseq:NP_477351.1|flybase:FBgn0024291 refseq:NP_476923.1|flybase:FBgn0010109|dip:DIP-19436N|ensemblmetazoa:FBgn0010109(gene)|ensemblmetazoa:FBtr0088803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|go:"GO:0007549"(dosage compensation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0043565"(sequence-specific DNA binding) pubmed:12086602(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:c+w67u0SypZji7O8yy/JsMFtAeA7227 rogid:U1CUdm2K6ZYMRIRNp8diHtOZAX87227 intact-crc:E303713479A84A41|rigid:LdQ0JKrn9kfGs/eYGAmzoFtxoFc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16371 uniprotkb:Q26263 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 intact:EBI-144502|uniprotkb:Q9V384|ensemblmetazoa:FBpp0087879 psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:dpn_drome(display_long)|uniprotkb:dpn(gene name)|psi-mi:dpn(display_short)|uniprotkb:CG8704(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872554 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N refseq:NP_476923.1|flybase:FBgn0010109|dip:DIP-19436N|ensemblmetazoa:FBgn0010109(gene)|ensemblmetazoa:FBtr0088803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|go:"GO:0007549"(dosage compensation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0043565"(sequence-specific DNA binding) pubmed:8001118(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 rogid:U1CUdm2K6ZYMRIRNp8diHtOZAX87227 intact-crc:3F5A284268B3D21E|rigid:EfUVIGrc4c5excEfcMwmnUAJCjo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P25723 uniprotkb:P07713 intact:EBI-115496|uniprotkb:Q9VC46|ensemblmetazoa:FBpp0084070 intact:EBI-499422|uniprotkb:P91651|uniprotkb:Q6AWM1|uniprotkb:Q8I0M7|uniprotkb:Q8ITK4|uniprotkb:Q9VQC6|uniprotkb:A4V009|ensemblmetazoa:FBpp0077451|ensemblmetazoa:FBpp0077452|ensemblmetazoa:FBpp0077453|ensemblmetazoa:FBpp0077455 psi-mi:tld_drome(display_long)|uniprotkb:tld(gene name)|psi-mi:tld(display_short)|uniprotkb:CG6868(orf name) psi-mi:deca_drome(display_long)|uniprotkb:dpp(gene name)|psi-mi:dpp(display_short)|uniprotkb:CG9885(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872558 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524487.2|flybase:FBgn0003719|ensemblmetazoa:FBgn0003719(gene)|ensemblmetazoa:FBtr0084691(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007313"(maternal specification of dorsal/ventral axis, oocyte, soma encoded)|go:"GO:0007378"(amnioserosa formation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0016485"(protein processing)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0045464"(R8 cell fate specification)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001506(Peptidase M12A, astacin)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR015446(Bone morphogenetic protein 1/tolloid-like protein)|interpro:IPR018097|interpro:IPR024079|interpro:IPR034036|interpro:IPR035914|reactome:R-DME-1650814|reactome:R-DME-2243919|interpro:IPR001881(EGF-like calcium-binding)|dip:DIP-22889N refseq:NP_477311.1|refseq:NP_722810.1|refseq:NP_722811.1|refseq:NP_722813.1|flybase:FBgn0000490|dip:DIP-19N|ensemblmetazoa:FBgn0000490(gene)|ensemblmetazoa:FBtr0077771(transcript)|ensemblmetazoa:FBtr0077772(transcript)|ensemblmetazoa:FBtr0077773(transcript)|ensemblmetazoa:FBtr0077775(transcript)|go:"GO:0001715"(ectodermal cell fate specification)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005125"(cytokine activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007281"(germ cell development)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007313"(maternal specification of dorsal/ventral axis, oocyte, soma encoded)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0007391"(dorsal closure)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007516"(hemocyte development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0007378"(amnioserosa formation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016015"(morphogen activity)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030721"(spectrosome organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0035156"(fusion cell fate specification)|go:"GO:0035158"(regulation of tube diameter, open tracheal system)|go:"GO:0035168"(larval lymph gland hemocyte differentiation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035215"(genital disc development)|go:"GO:0035217"(labial disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035263"(genital disc sexually dimorphic development)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0036098"(male germ-line stem cell population maintenance)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048542"(lymph gland development)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048636"(positive regulation of muscle organ development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0061327"(anterior Malpighian tubule development)|go:"GO:0061352"(cell chemotaxis involved in Malpighian tubule morphogenesis)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0098898"(dense core granule lumen)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001111("Transforming growth factor beta (TGFb), N-terminal")|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR017948|interpro:IPR029034|reactome:R-DME-114608|reactome:R-DME-201451|reactome:R-DME-381426|go:"GO:0009950"(dorsal/ventral axis specification)|reactome:R-DME-8957275 pubmed:8536976(see-also)|pubmed:9363950(see-also)|pubmed:7600963(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:YdMM4yIwCvr3BEfcOk1c7jBHcw07227 rogid:ahdsWqw3mytdXdl3x3PIVupVxEc7227 intact-crc:0374133ADB89B032|rigid:Mc5vuST5yi9IzwIOOk4r5HgEBvA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24326 uniprotkb:P07713 intact:EBI-869183 intact:EBI-499422|uniprotkb:P91651|uniprotkb:Q6AWM1|uniprotkb:Q8I0M7|uniprotkb:Q8ITK4|uniprotkb:Q9VQC6|uniprotkb:A4V009|ensemblmetazoa:FBpp0077451|ensemblmetazoa:FBpp0077452|ensemblmetazoa:FBpp0077453|ensemblmetazoa:FBpp0077455 psi-mi:q24326_drome(display_long)|uniprotkb:tkv(gene name)|psi-mi:tkv(display_short)|uniprotkb:dtfr(gene name synonym)|uniprotkb:CG14026(orf name) psi-mi:deca_drome(display_long)|uniprotkb:dpp(gene name)|psi-mi:dpp(display_short)|uniprotkb:CG9885(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872562 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0003716|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005025"(transforming growth factor beta receptor activity, type I)|go:"GO:0005524"(ATP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007391"(dorsal closure)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008354"(germ cell migration)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030721"(spectrosome organization)|go:"GO:0035215"(genital disc development)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0043235"(receptor complex)|go:"GO:0045202"(synapse)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0046332"(SMAD binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0060799"(transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification)|go:"GO:0061327"(anterior Malpighian tubule development)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|interpro:IPR000333(Activin type II receptor)|interpro:IPR000472(TGF-beta receptor/activin receptor, type I/II)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003605(TGF beta receptor, GS motif)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) refseq:NP_477311.1|refseq:NP_722810.1|refseq:NP_722811.1|refseq:NP_722813.1|flybase:FBgn0000490|dip:DIP-19N|ensemblmetazoa:FBgn0000490(gene)|ensemblmetazoa:FBtr0077771(transcript)|ensemblmetazoa:FBtr0077772(transcript)|ensemblmetazoa:FBtr0077773(transcript)|ensemblmetazoa:FBtr0077775(transcript)|go:"GO:0001715"(ectodermal cell fate specification)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005125"(cytokine activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007281"(germ cell development)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007313"(maternal specification of dorsal/ventral axis, oocyte, soma encoded)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0007391"(dorsal closure)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007516"(hemocyte development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0007378"(amnioserosa formation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016015"(morphogen activity)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030721"(spectrosome organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0035156"(fusion cell fate specification)|go:"GO:0035158"(regulation of tube diameter, open tracheal system)|go:"GO:0035168"(larval lymph gland hemocyte differentiation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035215"(genital disc development)|go:"GO:0035217"(labial disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035263"(genital disc sexually dimorphic development)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0036098"(male germ-line stem cell population maintenance)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048542"(lymph gland development)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048636"(positive regulation of muscle organ development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0061327"(anterior Malpighian tubule development)|go:"GO:0061352"(cell chemotaxis involved in Malpighian tubule morphogenesis)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0098898"(dense core granule lumen)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001111("Transforming growth factor beta (TGFb), N-terminal")|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR017948|interpro:IPR029034|reactome:R-DME-114608|reactome:R-DME-201451|reactome:R-DME-381426|go:"GO:0009950"(dorsal/ventral axis specification)|reactome:R-DME-8957275 pubmed:8044839(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:FB2IWkOHoz7sCHdulTN4juLDwhk7227 rogid:ahdsWqw3mytdXdl3x3PIVupVxEc7227 intact-crc:0664463EE97B0D29|rigid:r6Hy3Vdzupe4Mzl9ltkQz5zXkdg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7JQ36 uniprotkb:P07713 intact:EBI-121415|ensemblmetazoa:FBpp0087908 intact:EBI-499422|uniprotkb:P91651|uniprotkb:Q6AWM1|uniprotkb:Q8I0M7|uniprotkb:Q8ITK4|uniprotkb:Q9VQC6|uniprotkb:A4V009|ensemblmetazoa:FBpp0077451|ensemblmetazoa:FBpp0077452|ensemblmetazoa:FBpp0077453|ensemblmetazoa:FBpp0077455 psi-mi:q7jq36_drome(display_long)|uniprotkb:sax(gene name)|psi-mi:sax(display_short)|uniprotkb:Sax(gene name synonym)|uniprotkb:CG1891(orf name)|uniprotkb:Dmel_CG1891(orf name)|uniprotkb:Bkr43E(gene name synonym)|uniprotkb:Brk43E(gene name synonym)|uniprotkb:Dmel\CG1891(gene name synonym)|uniprotkb:SAX(gene name synonym)|uniprotkb:STK-B(gene name synonym)|uniprotkb:Sa(gene name synonym) psi-mi:deca_drome(display_long)|uniprotkb:dpp(gene name)|psi-mi:dpp(display_short)|uniprotkb:CG9885(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872566 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523652.2|flybase:FBgn0003317|ensemblmetazoa:FBgn0003317(gene)|ensemblmetazoa:FBtr0088832(transcript)|go:"GO:0004675"(transmembrane receptor protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008358"(maternal determination of anterior/posterior axis, embryo)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000333(Activin type II receptor)|interpro:IPR000472(TGF-beta receptor/activin receptor, type I/II)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003605(TGF beta receptor, GS motif)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) refseq:NP_477311.1|refseq:NP_722810.1|refseq:NP_722811.1|refseq:NP_722813.1|flybase:FBgn0000490|dip:DIP-19N|ensemblmetazoa:FBgn0000490(gene)|ensemblmetazoa:FBtr0077771(transcript)|ensemblmetazoa:FBtr0077772(transcript)|ensemblmetazoa:FBtr0077773(transcript)|ensemblmetazoa:FBtr0077775(transcript)|go:"GO:0001715"(ectodermal cell fate specification)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005125"(cytokine activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007281"(germ cell development)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007313"(maternal specification of dorsal/ventral axis, oocyte, soma encoded)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0007391"(dorsal closure)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007516"(hemocyte development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0007378"(amnioserosa formation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016015"(morphogen activity)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030721"(spectrosome organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0035156"(fusion cell fate specification)|go:"GO:0035158"(regulation of tube diameter, open tracheal system)|go:"GO:0035168"(larval lymph gland hemocyte differentiation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035215"(genital disc development)|go:"GO:0035217"(labial disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035263"(genital disc sexually dimorphic development)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0036098"(male germ-line stem cell population maintenance)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048542"(lymph gland development)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048636"(positive regulation of muscle organ development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0061327"(anterior Malpighian tubule development)|go:"GO:0061352"(cell chemotaxis involved in Malpighian tubule morphogenesis)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0098898"(dense core granule lumen)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001111("Transforming growth factor beta (TGFb), N-terminal")|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR017948|interpro:IPR029034|reactome:R-DME-114608|reactome:R-DME-201451|reactome:R-DME-381426|go:"GO:0009950"(dorsal/ventral axis specification)|reactome:R-DME-8957275 pubmed:8044839(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:5cRHvkW8tEh2vkAn6uLRSdu8/Y87227 rogid:ahdsWqw3mytdXdl3x3PIVupVxEc7227 intact-crc:255B00589A35D0B8|rigid:KIZkm7soFTUM5fe8+sQc7PqZYas false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07713 uniprotkb:Q24229 intact:EBI-499422|uniprotkb:P91651|uniprotkb:Q6AWM1|uniprotkb:Q8I0M7|uniprotkb:Q8ITK4|uniprotkb:Q9VQC6|uniprotkb:A4V009|ensemblmetazoa:FBpp0077451|ensemblmetazoa:FBpp0077452|ensemblmetazoa:FBpp0077453|ensemblmetazoa:FBpp0077455 intact:EBI-869214 psi-mi:deca_drome(display_long)|uniprotkb:dpp(gene name)|psi-mi:dpp(display_short)|uniprotkb:CG9885(orf name) psi-mi:q24229_drome(display_long)|uniprotkb:put(gene name)|psi-mi:put(display_short)|uniprotkb:CG7904(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872570 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477311.1|refseq:NP_722810.1|refseq:NP_722811.1|refseq:NP_722813.1|flybase:FBgn0000490|dip:DIP-19N|ensemblmetazoa:FBgn0000490(gene)|ensemblmetazoa:FBtr0077771(transcript)|ensemblmetazoa:FBtr0077772(transcript)|ensemblmetazoa:FBtr0077773(transcript)|ensemblmetazoa:FBtr0077775(transcript)|go:"GO:0001715"(ectodermal cell fate specification)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005125"(cytokine activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007281"(germ cell development)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007313"(maternal specification of dorsal/ventral axis, oocyte, soma encoded)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0007391"(dorsal closure)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007516"(hemocyte development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0007378"(amnioserosa formation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016015"(morphogen activity)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030721"(spectrosome organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0035156"(fusion cell fate specification)|go:"GO:0035158"(regulation of tube diameter, open tracheal system)|go:"GO:0035168"(larval lymph gland hemocyte differentiation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035215"(genital disc development)|go:"GO:0035217"(labial disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035263"(genital disc sexually dimorphic development)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0036098"(male germ-line stem cell population maintenance)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048542"(lymph gland development)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048636"(positive regulation of muscle organ development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0061327"(anterior Malpighian tubule development)|go:"GO:0061352"(cell chemotaxis involved in Malpighian tubule morphogenesis)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0098898"(dense core granule lumen)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001111("Transforming growth factor beta (TGFb), N-terminal")|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR017948|interpro:IPR029034|reactome:R-DME-114608|reactome:R-DME-201451|reactome:R-DME-381426|go:"GO:0009950"(dorsal/ventral axis specification)|reactome:R-DME-8957275 flybase:FBgn0003169|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007391"(dorsal closure)|go:"GO:0007411"(axon guidance)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007428"(primary branching, open tracheal system)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0008258"(head involution)|go:"GO:0017002"(activin-activated receptor activity)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0046872"(metal ion binding)|go:"GO:0048179"(activin receptor complex)|go:"GO:0048185"(activin binding)|go:"GO:0048666"(neuron development)|interpro:IPR000333(Activin type II receptor)|interpro:IPR000472(TGF-beta receptor/activin receptor, type I/II)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like) pubmed:7697720(see-also)|pubmed:7697719(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ahdsWqw3mytdXdl3x3PIVupVxEc7227 rogid:m+Pexdc07PthjexkqjIsK/JHstk7227 intact-crc:7ECE022F72A05411|rigid:o+u3RZlTQwH97dplrcZSAm5okPs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24306 uniprotkb:Q7KHK9 intact:EBI-456419|uniprotkb:A4V1Z9|uniprotkb:Q0E8E4|uniprotkb:Q8MRM5|uniprotkb:Q9VUX5|uniprotkb:A9UN33|ensemblmetazoa:FBpp0075254|ensemblmetazoa:FBpp0075255|ensemblmetazoa:FBpp0075256|ensemblmetazoa:FBpp0305793|ensemblmetazoa:FBpp0305794|ensemblmetazoa:FBpp0305795 intact:EBI-194303|ensemblmetazoa:FBpp0085364|ensemblmetazoa:FBpp0307275 psi-mi:diap1_drome(display_long)|uniprotkb:Diap1(gene name)|psi-mi:Diap1(display_short)|uniprotkb:Apoptosis 1 inhibitor(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase th(gene name synonym)|uniprotkb:Iap1(gene name synonym)|uniprotkb:Inhibitor of apoptosis 1(gene name synonym)|uniprotkb:Protein thread(gene name synonym)|uniprotkb:th(gene name synonym)|uniprotkb:CG12284(orf name)|uniprotkb:RING-type E3 ubiquitin transferase Diap1(gene name synonym) psi-mi:q7khk9_drome(display_long)|uniprotkb:Strica(gene name)|psi-mi:Strica(display_short)|uniprotkb:dream(gene name synonym)|uniprotkb:strica(gene name synonym)|uniprotkb:Dmel_CG7863(orf name)|uniprotkb:DREAM(gene name synonym)|uniprotkb:Dmel\CG7863(gene name synonym)|uniprotkb:Dream(gene name synonym)|uniprotkb:STRICA(gene name synonym)|uniprotkb:CG7863(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872574 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524101.2|refseq:NP_730097.1|refseq:NP_730098.1|flybase:FBgn0260635|refseq:NP_001261916.1|refseq:NP_001261917.1|refseq:NP_001261918.1|go:"GO:0006915"(apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0022416"(chaeta development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0045116"(protein neddylation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|ensemblmetazoa:FBgn0260635(gene)|ensemblmetazoa:FBtr0075499(transcript)|ensemblmetazoa:FBtr0075500(transcript)|ensemblmetazoa:FBtr0075501(transcript)|ensemblmetazoa:FBtr0333617(transcript)|ensemblmetazoa:FBtr0333618(transcript)|ensemblmetazoa:FBtr0333619(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|mint:Q24306|rcsb pdb:1JD4|rcsb pdb:1JD5|rcsb pdb:1JD6|rcsb pdb:1Q4Q|rcsb pdb:1SDZ|rcsb pdb:1SE0|rcsb pdb:3SIP|rcsb pdb:3SIQ|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-3769402|reactome:R-DME-390150|reactome:R-DME-5675482|reactome:R-DME-8948747|reactome:R-DME-8948751 refseq:NP_610193.1|flybase:FBgn0033051|refseq:NP_001260718.1|ensemblmetazoa:FBgn0033051(gene)|ensemblmetazoa:FBtr0086028(transcript)|ensemblmetazoa:FBtr0335289(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0035070"(salivary gland histolysis)|go:"GO:0045476"(nurse cell apoptotic process)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030 pubmed:11550090(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:loBQ//cKQ1NYhq3gnIKwRBn5vZg7227 rogid:a5utlMfnZYZXJvTKftiyzyFgC6g7227 intact-crc:0AF8824FF7DE6FD2|rigid:MT1EGljgxaZh423D+aEVXArq3iU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KHK9 uniprotkb:Q24307 intact:EBI-194303|ensemblmetazoa:FBpp0085364|ensemblmetazoa:FBpp0307275 intact:EBI-112046|uniprotkb:A4UZI4|uniprotkb:Q24115|uniprotkb:Q24149|uniprotkb:Q24177|uniprotkb:Q960U3|uniprotkb:Q9V7G1|ensemblmetazoa:FBpp0086431|ensemblmetazoa:FBpp0086432 psi-mi:q7khk9_drome(display_long)|uniprotkb:Strica(gene name)|psi-mi:Strica(display_short)|uniprotkb:dream(gene name synonym)|uniprotkb:strica(gene name synonym)|uniprotkb:Dmel_CG7863(orf name)|uniprotkb:DREAM(gene name synonym)|uniprotkb:Dmel\CG7863(gene name synonym)|uniprotkb:Dream(gene name synonym)|uniprotkb:STRICA(gene name synonym)|uniprotkb:CG7863(orf name) psi-mi:diap2_drome(display_long)|uniprotkb:Diap2(gene name)|psi-mi:Diap2(display_short)|uniprotkb:Apoptosis 2 inhibitor(gene name synonym)|uniprotkb:DIHA(gene name synonym)|uniprotkb:IAP homolog A(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:Iap2(gene name synonym)|uniprotkb:Ilp(gene name synonym)|uniprotkb:Inhibitor of apoptosis 2(gene name synonym)|uniprotkb:CG8293(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872578 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610193.1|flybase:FBgn0033051|refseq:NP_001260718.1|ensemblmetazoa:FBgn0033051(gene)|ensemblmetazoa:FBtr0086028(transcript)|ensemblmetazoa:FBtr0335289(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0035070"(salivary gland histolysis)|go:"GO:0045476"(nurse cell apoptotic process)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030 refseq:NP_477127.1|refseq:NP_788362.1|flybase:FBgn0015247|ensemblmetazoa:FBgn0015247(gene)|ensemblmetazoa:FBtr0087296(transcript)|ensemblmetazoa:FBtr0087297(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006964"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0022416"(chaeta development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-209447|reactome:R-DME-3769402|reactome:R-DME-5675482|reactome:R-DME-8948747|reactome:R-DME-8948751 pubmed:11550090(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:a5utlMfnZYZXJvTKftiyzyFgC6g7227 rogid:DV11DOWYIDsW1ADpZuGD9UtXpYM7227 intact-crc:7AF8EE525BAE7E82|rigid:7iA1vA3jEL34a0wJlqBNrTRzHE4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q94527 uniprotkb:Q8IRY7 intact:EBI-869024|uniprotkb:Q9U435|uniprotkb:Q9U436|uniprotkb:Q9U437|uniprotkb:Q9U438|uniprotkb:Q9U439|uniprotkb:Q9U440|uniprotkb:Q9U6H3|uniprotkb:Q9U6H4|uniprotkb:Q9U6H5|uniprotkb:Q9VHI0|uniprotkb:A4V2K3|ensemblmetazoa:FBpp0088375|ensemblmetazoa:FBpp0088971|ensemblmetazoa:FBpp0088973 intact:EBI-442182|ensemblmetazoa:FBpp0113052|uniprotkb:O02433|uniprotkb:O76797|uniprotkb:O76798|uniprotkb:Q95T94|uniprotkb:Q9UB42|uniprotkb:Q9W5E3 psi-mi:nfkb1_drome(display_long)|uniprotkb:Relish protein(gene name synonym)|uniprotkb:Rel-p110(gene name synonym)|uniprotkb:Rel(gene name)|psi-mi:Rel(display_short)|uniprotkb:CG11992(orf name) psi-mi:casp8_drome(display_long)|uniprotkb:Death-related ced-3/NEDD2-like protein(gene name synonym)|uniprotkb:Dredd(gene name)|psi-mi:Dredd(display_short)|uniprotkb:DCP2(gene name synonym)|uniprotkb:CG7486(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872582 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477094.1|refseq:NP_996187.1|refseq:NP_996188.1|refseq:NP_996189.1|flybase:FBgn0014018|dip:DIP-60434N|ensemblmetazoa:FBgn0014018(gene)|ensemblmetazoa:FBtr0089338(transcript)|ensemblmetazoa:FBtr0089339(transcript)|ensemblmetazoa:FBtr0089340(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0006964"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0006967"(positive regulation of antifungal peptide biosynthetic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051607"(defense response to virus)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:2000647"(negative regulation of stem cell proliferation)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|reactome:R-DME-1169091|reactome:R-DME-1810476|reactome:R-DME-202424|reactome:R-DME-209394|reactome:R-DME-209560|reactome:R-DME-214399|reactome:R-DME-214411|reactome:R-DME-214416|reactome:R-DME-2871837|reactome:R-DME-3134963|reactome:R-DME-445989|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5621575|reactome:R-DME-5676590|reactome:R-DME-6798695|reactome:R-DME-9020702|reactome:R-DME-933542 ensemblmetazoa:FBgn0020381(gene)|ensemblmetazoa:FBtr0114560(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0006955"(immune response)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0006964"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0007291"(sperm individualization)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0016485"(protein processing)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|reactome:R-DME-198323|reactome:R-DME-214397|reactome:R-DME-214399|reactome:R-DME-214411|reactome:R-DME-214416|reactome:R-DME-448706|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|flybase:FBgn0020381|refseq:NP_477249.3|refseq:NP_477250.3|refseq:NP_477251.3 pubmed:11269501(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:QSjX/buJS65odmpaKMzPkTgHW/Y7227 rogid:8VF2wS5q6ZXJbm/BlLH8aUFz9bw7227 intact-crc:40353C87AAB3279D|rigid:Pe5U8D0ZIDiTQDVSXWWBF1OFRkY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KA83 uniprotkb:O96083 intact:EBI-869253|ensemblmetazoa:FBpp0111840 intact:EBI-869243 psi-mi:q7ka83_drome(display_long)|uniprotkb:Trf2(gene name)|psi-mi:Trf2(display_short)|uniprotkb:TLF(gene name synonym)|uniprotkb:CG18009(orf name)|uniprotkb:TBP-like factor(gene name synonym) psi-mi:o96083_drome(display_long)|uniprotkb:Dref(gene name)|psi-mi:Dref(display_short)|uniprotkb:DREF(gene name synonym)|uniprotkb:CG5838(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872586 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261793|ensemblmetazoa:FBgn0261793(gene)|ensemblmetazoa:FBtr0112927(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035209"(pupal development)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR015445(TATA-Box binding protein-like) flybase:FBgn0015664|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0022416"(chaeta development)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051900"(regulation of mitochondrial depolarization)|go:"GO:2000278"(regulation of DNA biosynthetic process)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236 pubmed:12459787(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:G7b+30YKaa6wwY/9fOikO89CHXM7227 rogid:EC0yoUSZW+vNIkV72Tjh7SLGdHM7227 intact-crc:A52D774A78525B20|rigid:TS2ujyFKM1AlK3BYPdva8vGdGO4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9NKV0 uniprotkb:O96083 intact:EBI-172802|uniprotkb:A1ZA61|uniprotkb:A1ZA62|uniprotkb:Q540Y3|uniprotkb:Q8IG90|uniprotkb:Q95P43|uniprotkb:Q9V7G3|ensemblmetazoa:FBpp0089346 intact:EBI-869243 psi-mi:mlf_drome(display_long)|uniprotkb:Mlf(gene name)|psi-mi:Mlf(display_short)|uniprotkb:CG8295(orf name)|uniprotkb:Myelodysplasia-myeloid leukemia factor(gene name synonym) psi-mi:o96083_drome(display_long)|uniprotkb:Dref(gene name)|psi-mi:Dref(display_short)|uniprotkb:DREF(gene name synonym)|uniprotkb:CG5838(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872590 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523753.1|refseq:NP_725501.2|refseq:NP_725502.1|refseq:NP_995847.1|flybase:FBgn0034051|ensemblmetazoa:FBgn0034051(gene)|ensemblmetazoa:FBtr0087295(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR019376 flybase:FBgn0015664|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0022416"(chaeta development)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051900"(regulation of mitochondrial depolarization)|go:"GO:2000278"(regulation of DNA biosynthetic process)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236 pubmed:11137299(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KczdABKCmzLycD8vxaBvfphu+EU7227 rogid:EC0yoUSZW+vNIkV72Tjh7SLGdHM7227 intact-crc:EF574AE1BE722C1E|rigid:4H4+rPkGwZM0kcc4wGhHYjG6o1M false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O96083 uniprotkb:O97159 intact:EBI-869243 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 psi-mi:o96083_drome(display_long)|uniprotkb:Dref(gene name)|psi-mi:Dref(display_short)|uniprotkb:DREF(gene name synonym)|uniprotkb:CG5838(orf name) psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872594 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0015664|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0022416"(chaeta development)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051900"(regulation of mitochondrial depolarization)|go:"GO:2000278"(regulation of DNA biosynthetic process)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236 refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724 pubmed:12077345(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:EC0yoUSZW+vNIkV72Tjh7SLGdHM7227 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 intact-crc:1FECCE44B08272DD|rigid:IB9hJs0sO30wraqGMG4TxM/7gX0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O44783 uniprotkb:Q08012 intact:EBI-132097|uniprotkb:A4V1F3|uniprotkb:Q6AWR4|uniprotkb:Q9VZP7|ensemblmetazoa:FBpp0073004|ensemblmetazoa:FBpp0073005 intact:EBI-161391|uniprotkb:Q0E989|uniprotkb:Q9V6Q5|uniprotkb:A4UZF9|ensemblmetazoa:FBpp0086813|ensemblmetazoa:FBpp0086814|ensemblmetazoa:FBpp0086815|ensemblmetazoa:FBpp0086816|ensemblmetazoa:FBpp0086817 psi-mi:spy_drome(display_long)|uniprotkb:sty(gene name)|psi-mi:sty(display_short)|uniprotkb:CG1921(orf name) psi-mi:grap_drome(display_long)|uniprotkb:drk(gene name)|psi-mi:drk(display_short)|uniprotkb:"E(sev)2B"(gene name synonym)|uniprotkb:Downstream of receptor kinase(gene name synonym)|uniprotkb:Grb2(gene name synonym)|uniprotkb:Protein enhancer of sevenless 2B(gene name synonym)|uniprotkb:CG6033(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872598 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523902.2|refseq:NP_728881.1|flybase:FBgn0014388|ensemblmetazoa:FBgn0014388(gene)|ensemblmetazoa:FBtr0073145(transcript)|ensemblmetazoa:FBtr0073146(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0021782"(glial cell development)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045314"(regulation of compound eye photoreceptor development)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0055001"(muscle cell development)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0110109"(negative regulation of imaginal disc-derived wing vein specification)|interpro:IPR007875(Sprouty)|reactome:R-DME-1295596|reactome:R-DME-182971|go:"GO:0120177"(negative regulation of torso signaling pathway)|dip:DIP-17914N refseq:NP_476858.1|refseq:NP_725302.1|refseq:NP_725303.1|refseq:NP_725304.1|refseq:NP_725306.1|flybase:FBgn0004638|ensemblmetazoa:FBgn0004638(gene)|ensemblmetazoa:FBtr0087694(transcript)|ensemblmetazoa:FBtr0087695(transcript)|ensemblmetazoa:FBtr0087696(transcript)|ensemblmetazoa:FBtr0087697(transcript)|ensemblmetazoa:FBtr0087698(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005118"(sevenless binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007614"(short-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR030219|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2A36|go:"GO:0008306"(associative learning)|rcsb pdb:2A37|rcsb pdb:2AZS|rcsb pdb:2AZV|reactome:R-DME-109704|reactome:R-DME-112412|reactome:R-DME-1250347|reactome:R-DME-1257604|reactome:R-DME-1295596|reactome:R-DME-1433557|reactome:R-DME-1433559|reactome:R-DME-167044|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-1963642|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2428933|reactome:R-DME-2730905|reactome:R-DME-2871796|reactome:R-DME-2871809|reactome:R-DME-375165|reactome:R-DME-5654688|go:"GO:0008355"(olfactory learning)|reactome:R-DME-5654689|reactome:R-DME-5654693|reactome:R-DME-5654695|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654710|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5654720|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5673001|reactome:R-DME-6811558|reactome:R-DME-74749|reactome:R-DME-74751|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-9027284|reactome:R-DME-912631|reactome:R-DME-9607240|reactome:R-DME-983695|reactome:R-DME-5654733|dip:DIP-21223N pubmed:10089881(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Epk95p/MSvHN+VVqzKqaTdmoO6g7227 rogid:GNPfKX2LH0HRXEW4ASFDTrXN3VY7227 intact-crc:48487128E819D15D|rigid:DGp0CsNJwQlre8jEW4QhgBbblzg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P26675 uniprotkb:Q08012 intact:EBI-82070|uniprotkb:Q6AWF4|uniprotkb:Q8I067|uniprotkb:Q8I0F7|uniprotkb:Q8ITK2|uniprotkb:Q95TI8|uniprotkb:Q969D6|uniprotkb:Q9VJV9|ensemblmetazoa:FBpp0080118 intact:EBI-161391|uniprotkb:Q0E989|uniprotkb:Q9V6Q5|uniprotkb:A4UZF9|ensemblmetazoa:FBpp0086813|ensemblmetazoa:FBpp0086814|ensemblmetazoa:FBpp0086815|ensemblmetazoa:FBpp0086816|ensemblmetazoa:FBpp0086817 psi-mi:sos_drome(display_long)|uniprotkb:Sos(gene name)|psi-mi:Sos(display_short)|uniprotkb:CG7793(orf name) psi-mi:grap_drome(display_long)|uniprotkb:drk(gene name)|psi-mi:drk(display_short)|uniprotkb:"E(sev)2B"(gene name synonym)|uniprotkb:Downstream of receptor kinase(gene name synonym)|uniprotkb:Grb2(gene name synonym)|uniprotkb:Protein enhancer of sevenless 2B(gene name synonym)|uniprotkb:CG6033(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872602 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476597.2|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR007125(Histone core)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR035899|interpro:IPR036964|rcsb pdb:1AZE|reactome:R-DME-112412|reactome:R-DME-1250347|reactome:R-DME-1433557|reactome:R-DME-1433559|reactome:R-DME-167044|reactome:R-DME-179812|reactome:R-DME-180336|reactome:R-DME-186763|reactome:R-DME-193648|reactome:R-DME-1963640|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2428933|reactome:R-DME-2730905|reactome:R-DME-2871796|reactome:R-DME-2871809|reactome:R-DME-375165|reactome:R-DME-416482|reactome:R-DME-5654688|reactome:R-DME-5654693|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5673001|reactome:R-DME-74749|reactome:R-DME-74751|reactome:R-DME-9013149|reactome:R-DME-9607240|ensemblmetazoa:FBgn0001965(gene)|ensemblmetazoa:FBtr0080541(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035997"(rhabdomere microvillus membrane)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045500"(sevenless signaling pathway)|flybase:FBgn0001965|dip:DIP-22308N refseq:NP_476858.1|refseq:NP_725302.1|refseq:NP_725303.1|refseq:NP_725304.1|refseq:NP_725306.1|flybase:FBgn0004638|ensemblmetazoa:FBgn0004638(gene)|ensemblmetazoa:FBtr0087694(transcript)|ensemblmetazoa:FBtr0087695(transcript)|ensemblmetazoa:FBtr0087696(transcript)|ensemblmetazoa:FBtr0087697(transcript)|ensemblmetazoa:FBtr0087698(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005118"(sevenless binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007614"(short-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR030219|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2A36|go:"GO:0008306"(associative learning)|rcsb pdb:2A37|rcsb pdb:2AZS|rcsb pdb:2AZV|reactome:R-DME-109704|reactome:R-DME-112412|reactome:R-DME-1250347|reactome:R-DME-1257604|reactome:R-DME-1295596|reactome:R-DME-1433557|reactome:R-DME-1433559|reactome:R-DME-167044|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-1963642|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2428933|reactome:R-DME-2730905|reactome:R-DME-2871796|reactome:R-DME-2871809|reactome:R-DME-375165|reactome:R-DME-5654688|go:"GO:0008355"(olfactory learning)|reactome:R-DME-5654689|reactome:R-DME-5654693|reactome:R-DME-5654695|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654710|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5654720|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5673001|reactome:R-DME-6811558|reactome:R-DME-74749|reactome:R-DME-74751|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-9027284|reactome:R-DME-912631|reactome:R-DME-9607240|reactome:R-DME-983695|reactome:R-DME-5654733|dip:DIP-21223N pubmed:8462098(see-also)|pubmed:7781603(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:TxXgLxqhzkv9TdP1KrgoN7wEyFo7227 rogid:GNPfKX2LH0HRXEW4ASFDTrXN3VY7227 intact-crc:BFFEA54CE80B9D80|rigid:S9Yt7EKFy90bw6gCt8/k4yhutMk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7JNX6 uniprotkb:Q08012 intact:EBI-869298 intact:EBI-161391|uniprotkb:Q0E989|uniprotkb:Q9V6Q5|uniprotkb:A4UZF9|ensemblmetazoa:FBpp0086813|ensemblmetazoa:FBpp0086814|ensemblmetazoa:FBpp0086815|ensemblmetazoa:FBpp0086816|ensemblmetazoa:FBpp0086817 psi-mi:q7jnx6_drome(display_long)|uniprotkb:Pi3K68D(gene name)|psi-mi:Pi3K68D(display_short)|uniprotkb:cpk(gene name synonym)|uniprotkb:CG11621(orf name) psi-mi:grap_drome(display_long)|uniprotkb:drk(gene name)|psi-mi:drk(display_short)|uniprotkb:"E(sev)2B"(gene name synonym)|uniprotkb:Downstream of receptor kinase(gene name synonym)|uniprotkb:Grb2(gene name synonym)|uniprotkb:Protein enhancer of sevenless 2B(gene name synonym)|uniprotkb:CG6033(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872610 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0015278|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0010008"(endosome membrane)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016477"(cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR001683(Phox-like)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036871|interpro:IPR036940|interpro:IPR042236 refseq:NP_476858.1|refseq:NP_725302.1|refseq:NP_725303.1|refseq:NP_725304.1|refseq:NP_725306.1|flybase:FBgn0004638|ensemblmetazoa:FBgn0004638(gene)|ensemblmetazoa:FBtr0087694(transcript)|ensemblmetazoa:FBtr0087695(transcript)|ensemblmetazoa:FBtr0087696(transcript)|ensemblmetazoa:FBtr0087697(transcript)|ensemblmetazoa:FBtr0087698(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005118"(sevenless binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007614"(short-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR030219|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2A36|go:"GO:0008306"(associative learning)|rcsb pdb:2A37|rcsb pdb:2AZS|rcsb pdb:2AZV|reactome:R-DME-109704|reactome:R-DME-112412|reactome:R-DME-1250347|reactome:R-DME-1257604|reactome:R-DME-1295596|reactome:R-DME-1433557|reactome:R-DME-1433559|reactome:R-DME-167044|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-1963642|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2428933|reactome:R-DME-2730905|reactome:R-DME-2871796|reactome:R-DME-2871809|reactome:R-DME-375165|reactome:R-DME-5654688|go:"GO:0008355"(olfactory learning)|reactome:R-DME-5654689|reactome:R-DME-5654693|reactome:R-DME-5654695|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654710|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5654720|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5673001|reactome:R-DME-6811558|reactome:R-DME-74749|reactome:R-DME-74751|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-9027284|reactome:R-DME-912631|reactome:R-DME-9607240|reactome:R-DME-983695|reactome:R-DME-5654733|dip:DIP-21223N pubmed:14701751(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:G/CxPug7CTMg5diBXpgl6jC8YeA7227 rogid:GNPfKX2LH0HRXEW4ASFDTrXN3VY7227 intact-crc:BF8F8A98682C3845|rigid:L+p1n+uO5LIakDk0to0psE25kzk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9NCC3 uniprotkb:A1Z6X2 intact:EBI-163600|uniprotkb:Q9VT36|ensemblmetazoa:FBpp0076142 intact:EBI-869317|intact:EBI-3409713|ensemblmetazoa:FBpp0089327 psi-mi:q9ncc3_drome(display_long)|uniprotkb:SH3PX1(gene name)|psi-mi:SH3PX1(display_short)|uniprotkb:DSH3PX1(gene name synonym)|uniprotkb:DSH3PX(gene name synonym)|uniprotkb:DmSNX18(gene name synonym)|uniprotkb:Dmel\CG6757(gene name synonym)|uniprotkb:dSH3PX1(gene name synonym)|uniprotkb:p63(gene name synonym)|uniprotkb:sh3px1(gene name synonym)|uniprotkb:Dmel_CG6757(orf name)|uniprotkb:CG6757(orf name)|uniprotkb:Sh3px1(gene name synonym) psi-mi:a1z6x2_drome(display_long)|uniprotkb:Dscam1(gene name)|psi-mi:Dscam1(display_short)|uniprotkb:Dscam(gene name synonym)|uniprotkb:43Bc(gene name synonym)|uniprotkb:CT39257(gene name synonym)|uniprotkb:DSCAM(gene name synonym)|uniprotkb:DScam(gene name synonym)|uniprotkb:DmDscam(gene name synonym)|uniprotkb:"Dm_2R:13579"(gene name synonym)|uniprotkb:"Dm_2R:13612"(gene name synonym)|uniprotkb:Dmel\CG17800(gene name synonym)|uniprotkb:DsCam(gene name synonym)|uniprotkb:Dscam-hv(gene name synonym)|uniprotkb:Dsm(gene name synonym)|uniprotkb:Neu1(gene name synonym)|uniprotkb:dScam(gene name synonym)|uniprotkb:dscam1(gene name synonym)|uniprotkb:"l(2)05518"(gene name synonym)|uniprotkb:"l(2)43Bc"(gene name synonym)|uniprotkb:p270(gene name synonym)|uniprotkb:CG17800(orf name)|uniprotkb:Dmel_CG17800(orf name)|uniprotkb:dscam(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872614 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648348.1|flybase:FBgn0040475|ensemblmetazoa:FBgn0040475(gene)|ensemblmetazoa:FBtr0076413(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0015031"(protein transport)|go:"GO:0019900"(kinase binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1990709"(presynaptic active zone organization)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR036028|interpro:IPR036871|reactome:R-DME-432722|reactome:R-DME-8856828 refseq:NP_995769.1|flybase:FBgn0033159|ensemblmetazoa:FBgn0033159(gene)|ensemblmetazoa:FBtr0089020(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0016319"(mushroom body development)|go:"GO:0021551"(central nervous system morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032490"(detection of molecule of bacterial origin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048666"(neuron development)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050976"(detection of mechanical stimulus involved in sensory perception of touch)|go:"GO:0070593"(dendrite self-avoidance)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR021012|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204 pubmed:11546816(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:sGeWtqBEWF+Y5aaq9lX9EoKO5aE7227 rogid:JvyxNIp3+FWkkir2xe49efTk/q87227 intact-crc:6D03F288EB7C057C|rigid:KY8ZlyAEbO3gRVZIlJVt30jWTAE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q3YNB2 uniprotkb:P51140 intact:EBI-869336 intact:EBI-499383|ensemblmetazoa:FBpp0073310|uniprotkb:Q494J5|uniprotkb:Q9VYZ9 psi-mi:q3ynb2_drome(display_long)|uniprotkb:pk(gene name)|psi-mi:pk(display_short)|uniprotkb:CG11084(orf name) psi-mi:dsh_drome(display_long)|uniprotkb:dsh(gene name)|psi-mi:dsh(display_short)|uniprotkb:CG18361(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872618 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0003090 refseq:NP_511118.2|flybase:FBgn0000499|ensemblmetazoa:FBgn0000499(gene)|ensemblmetazoa:FBtr0073454(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-201688|reactome:R-DME-2028269|reactome:R-DME-209440|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641258|reactome:R-DME-4641262|reactome:R-DME-5099900|reactome:R-DME-5663220|reactome:R-DME-8856825|reactome:R-DME-8856828|interpro:IPR038207 pubmed:12015986(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:VwW7JQR+5/MnS2Nvz7RID5sPxF47227 rogid:zXo1t6bIifQ3/t3hf/MVeEuPw9A7227 intact-crc:3280AF971C685BBA|rigid:Ku+2qULpS46CScXBqBOxEpBTyxU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07207 uniprotkb:P51140 intact:EBI-103438|uniprotkb:O97458|uniprotkb:P04154|uniprotkb:Q9W4T8|ensemblmetazoa:FBpp0070483|ensemblmetazoa:FBpp0293201 intact:EBI-499383|ensemblmetazoa:FBpp0073310|uniprotkb:Q494J5|uniprotkb:Q9VYZ9 psi-mi:notch_drome(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:CG3936(orf name) psi-mi:dsh_drome(display_long)|uniprotkb:dsh(gene name)|psi-mi:dsh(display_short)|uniprotkb:CG18361(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872626 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476859.2|flybase:FBgn0004647|ensemblmetazoa:FBgn0004647(gene)|ensemblmetazoa:FBtr0070507(transcript)|ensemblmetazoa:FBtr0304659(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002213"(defense response to insect)|go:"GO:0003682"(chromatin binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007391"(dorsal closure)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009608"(response to symbiont)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0022416"(chaeta development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0007498"(mesoderm development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0007616"(long-term memory)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0040008"(regulation of growth)|go:"GO:0042686"(regulation of cardioblast cell fate specification)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045316"(negative regulation of compound eye photoreceptor development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048627"(myoblast development)|go:"GO:0048664"(neuron fate determination)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050699"(WW domain binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0060289"(compartment boundary maintenance)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990433"(CSL-Notch-Mastermind transcription factor complex)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1OT8|rcsb pdb:2JMF|refseq:NP_001245510.1|dip:DIP-5N refseq:NP_511118.2|flybase:FBgn0000499|ensemblmetazoa:FBgn0000499(gene)|ensemblmetazoa:FBtr0073454(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-201688|reactome:R-DME-2028269|reactome:R-DME-209440|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641258|reactome:R-DME-4641262|reactome:R-DME-5099900|reactome:R-DME-5663220|reactome:R-DME-8856825|reactome:R-DME-8856828|interpro:IPR038207 pubmed:10028968(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:T1iHJGMHXkhxbFRybmSDlizN7oQ7227 rogid:zXo1t6bIifQ3/t3hf/MVeEuPw9A7227 intact-crc:C36BB2CCEAC931C4|rigid:fdu/+hdmR8K9GZyzXxHJ+3tViVI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18537 uniprotkb:P51140 intact:EBI-251576|uniprotkb:Q9VUE0|uniprotkb:Q9VUE2|intact:EBI-251599|ensemblmetazoa:FBpp0075485 intact:EBI-499383|ensemblmetazoa:FBpp0073310|uniprotkb:Q494J5|uniprotkb:Q9VYZ9 psi-mi:friz_drome(display_long)|uniprotkb:fz(gene name)|psi-mi:fz(display_short)|uniprotkb:CG17697(orf name)|uniprotkb:Frizzled-1(gene name synonym) psi-mi:dsh_drome(display_long)|uniprotkb:dsh(gene name)|psi-mi:dsh(display_short)|uniprotkb:CG18361(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872630 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524812.1|flybase:FBgn0001085|dip:DIP-22727N|ensemblmetazoa:FBgn0001085(gene)|ensemblmetazoa:FBtr0075743(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0007494"(midgut development)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035320"(imaginal disc-derived wing hair site selection)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0042685"(cardioblast cell fate specification)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048675"(axon extension)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026552|interpro:IPR036790|reactome:R-DME-209387|reactome:R-DME-209440|reactome:R-DME-209472|reactome:R-DME-350368|reactome:R-DME-350376|reactome:R-DME-350379|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086398|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641262|reactome:R-DME-5140745 refseq:NP_511118.2|flybase:FBgn0000499|ensemblmetazoa:FBgn0000499(gene)|ensemblmetazoa:FBtr0073454(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-201688|reactome:R-DME-2028269|reactome:R-DME-209440|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641258|reactome:R-DME-4641262|reactome:R-DME-5099900|reactome:R-DME-5663220|reactome:R-DME-8856825|reactome:R-DME-8856828|interpro:IPR038207 pubmed:9716412(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:4tfZSq+RV6xKUPYq7P2V6Nkvzxs7227 rogid:zXo1t6bIifQ3/t3hf/MVeEuPw9A7227 intact-crc:94BD805F4EF0A3FF|rigid:H2kCTPhDHnr9Be6WeniNeTaoCQY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40417 uniprotkb:Q24324 intact:EBI-867790|uniprotkb:A0A021WW06|uniprotkb:Q7PL59|uniprotkb:Q9W5M2|uniprotkb:A8Y4W1|uniprotkb:A8Y4W2|uniprotkb:Q9W5M3|ensemblmetazoa:FBpp0112423|ensemblmetazoa:FBpp0112425|ensemblmetazoa:FBpp0112426|ensemblmetazoa:FBpp0311493 intact:EBI-671282|ensemblmetazoa:FBpp0071248|uniprotkb:Q8ISE0|uniprotkb:Q9W360 psi-mi:erka_drome(display_long)|uniprotkb:Extracellular-regulated kinase A(gene name synonym)|uniprotkb:Protein rolled(gene name synonym)|uniprotkb:rl(gene name)|psi-mi:rl(display_short)|uniprotkb:ERKa(gene name synonym)|uniprotkb:CG12559(orf name)|uniprotkb:MAPK(gene name synonym) psi-mi:dsor1_drome(display_long)|uniprotkb:Dsor1(gene name)|psi-mi:Dsor1(display_short)|uniprotkb:CG15793(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872634 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001015121.3|refseq:NP_001104348.2|refseq:NP_001287635.1|refseq:NP_001015122.1|refseq:NP_001015123.1|refseq:NP_001104349.1|flybase:FBgn0003256|dip:DIP-17266N|ensemblmetazoa:FBgn0003256(gene)|ensemblmetazoa:FBtr0113700(transcript)|ensemblmetazoa:FBtr0113702(transcript)|ensemblmetazoa:FBtr0113703(transcript)|ensemblmetazoa:FBtr0345337(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007362"(terminal region determination)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000826"(regulation of heart morphogenesis)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P40417|reactome:R-DME-110056|reactome:R-DME-112409|reactome:R-DME-112411|reactome:R-DME-1295596|reactome:R-DME-162658|reactome:R-DME-170968|reactome:R-DME-198753|reactome:R-DME-202670|reactome:R-DME-2029482|reactome:R-DME-2559580|reactome:R-DME-2559582|reactome:R-DME-2559585|reactome:R-DME-2871796|reactome:R-DME-3371453|reactome:R-DME-375165|reactome:R-DME-437239|reactome:R-DME-445144|reactome:R-DME-450341|reactome:R-DME-456926|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5654733|reactome:R-DME-5663213|reactome:R-DME-5673001|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5687128|reactome:R-DME-6798695|reactome:R-DME-74749|reactome:R-DME-881907|reactome:R-DME-9634635|reactome:R-DME-9634638 ensemblmetazoa:FBgn0010269(gene)|ensemblmetazoa:FBtr0071313(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000793"(condensed chromosome)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007430"(terminal branching, open tracheal system)|refseq:NP_511098.1|flybase:FBgn0010269|refseq:NP_001285044.1|dip:DIP-29770N|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019900"(kinase binding)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042386"(hemocyte differentiation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-110056|reactome:R-DME-112411|reactome:R-DME-170968|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-432553|reactome:R-DME-445144|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5674499 pubmed:8798773(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:m7w7KhuZSyx3t+dR2TKtvx/vRtA7227 rogid:FsIuc6ILmQjnAJmLsgb17lwXMU07227 intact-crc:F24E59051B7BDC1D|rigid:O4mTid+0mgXkhPQrZoey6UTk+uY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P11346 uniprotkb:Q24324 intact:EBI-664624|uniprotkb:Q9W4Z3|uniprotkb:Q8I086|uniprotkb:Q8I0D9|uniprotkb:Q8ISE1|uniprotkb:Q8ISE2|uniprotkb:Q8ISE3|uniprotkb:Q9NEH9|uniprotkb:A8JUV5|uniprotkb:Q0KHW7|ensemblmetazoa:FBpp0070385|ensemblmetazoa:FBpp0310458 intact:EBI-671282|ensemblmetazoa:FBpp0071248|uniprotkb:Q8ISE0|uniprotkb:Q9W360 psi-mi:kraf1_drome(display_long)|uniprotkb:Raf(gene name)|psi-mi:Raf(display_short)|uniprotkb:Protein pole-hole(gene name synonym)|uniprotkb:ph(gene name synonym)|uniprotkb:phl(gene name synonym)|uniprotkb:CG2845(orf name) psi-mi:dsor1_drome(display_long)|uniprotkb:Dsor1(gene name)|psi-mi:Dsor1(display_short)|uniprotkb:CG15793(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872638 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525047.1|flybase:FBgn0003079|refseq:NP_001096867.3|dip:DIP-29769N|ensemblmetazoa:FBgn0003079(gene)|ensemblmetazoa:FBtr0070401(transcript)|ensemblmetazoa:FBtr0344007(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0002168"(instar larval development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007552"(metamorphosis)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042386"(hemocyte differentiation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029071|reactome:R-DME-1295596|reactome:R-DME-170968|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-432553|reactome:R-DME-5621575|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5675482 ensemblmetazoa:FBgn0010269(gene)|ensemblmetazoa:FBtr0071313(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000793"(condensed chromosome)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007430"(terminal branching, open tracheal system)|refseq:NP_511098.1|flybase:FBgn0010269|refseq:NP_001285044.1|dip:DIP-29770N|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019900"(kinase binding)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042386"(hemocyte differentiation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-110056|reactome:R-DME-112411|reactome:R-DME-170968|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-432553|reactome:R-DME-445144|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5674499 pubmed:11850406(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:rbvsd7+5RvYrFoXyonEM6Li84hM7227 rogid:FsIuc6ILmQjnAJmLsgb17lwXMU07227 intact-crc:8CB5D26F682BF98E|rigid:hhwlNXGA0yislHmqux9SCe1Tyro false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24170 uniprotkb:Q24324 intact:EBI-868769 intact:EBI-671282|ensemblmetazoa:FBpp0071248|uniprotkb:Q8ISE0|uniprotkb:Q9W360 psi-mi:q24170_drome(display_long)|uniprotkb:ksr(gene name)|psi-mi:ksr(display_short)|uniprotkb:CG2899(orf name) psi-mi:dsor1_drome(display_long)|uniprotkb:Dsor1(gene name)|psi-mi:Dsor1(display_short)|uniprotkb:CG15793(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872642 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0015402|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR025561|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-432553 ensemblmetazoa:FBgn0010269(gene)|ensemblmetazoa:FBtr0071313(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000793"(condensed chromosome)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007430"(terminal branching, open tracheal system)|refseq:NP_511098.1|flybase:FBgn0010269|refseq:NP_001285044.1|dip:DIP-29770N|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019900"(kinase binding)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042386"(hemocyte differentiation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-110056|reactome:R-DME-112411|reactome:R-DME-170968|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-432553|reactome:R-DME-445144|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5674499 pubmed:11850406(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ZsbLCPNIB7ojheTNUv7Htgd7Yrg7227 rogid:FsIuc6ILmQjnAJmLsgb17lwXMU07227 intact-crc:CBCDAE75296889EB|rigid:tFW7Dr1D6pPbZcdj5P90vDatMtE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KBL8 uniprotkb:P23023 intact:EBI-96589|intact:EBI-2108658|uniprotkb:Q0IGZ7|ensemblmetazoa:FBpp0087251 intact:EBI-196709|uniprotkb:P23022|uniprotkb:Q0KIA7|uniprotkb:Q95TA5|uniprotkb:Q9VHY0|ensemblmetazoa:FBpp0081256|ensemblmetazoa:FBpp0303106 psi-mi:med29_drome(display_long)|uniprotkb:ix(gene name)|psi-mi:ix(display_short)|uniprotkb:MED29(gene name synonym)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Protein intersex(gene name synonym)|uniprotkb:CG13201(orf name) psi-mi:dsx_drome(display_long)|uniprotkb:dsx(gene name)|psi-mi:dsx(display_short)|uniprotkb:CG11094(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872646 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610677.1|flybase:FBgn0001276|ensemblmetazoa:FBgn0001276(gene)|ensemblmetazoa:FBtr0088154(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0018993"(somatic sex determination)|go:"GO:0019101"(female somatic sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0035263"(genital disc sexually dimorphic development)|go:"GO:0048804"(imaginal disc-derived female genitalia morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|interpro:IPR021018 refseq:NP_524272.4|refseq:NP_731197.1|refseq:NP_731198.1|flybase:FBgn0000504|refseq:NP_001287220.1|refseq:NP_001262352.1|dip:DIP-17110N|ensemblmetazoa:FBgn0000504(gene)|ensemblmetazoa:FBtr0081759(transcript)|ensemblmetazoa:FBtr0330073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007485"(imaginal disc-derived male genitalia development)|go:"GO:0007486"(imaginal disc-derived female genitalia development)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0007619"(courtship behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0018993"(somatic sex determination)|go:"GO:0019101"(female somatic sex determination)|go:"GO:0035215"(genital disc development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0045496"(male analia development)|go:"GO:0045497"(female analia development)|go:"GO:0045498"(sex comb development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046660"(female sex differentiation)|go:"GO:0046661"(male sex differentiation)|go:"GO:0048071"(sex-specific pigmentation)|go:"GO:0048086"(negative regulation of developmental pigmentation)|interpro:IPR001275(DM DNA-binding)|interpro:IPR014932(Doublesex dimerisation)|interpro:IPR026607|interpro:IPR036407|rcsb pdb:1LPV|rcsb pdb:1ZV1|rcsb pdb:2JZ0|rcsb pdb:2JZ1 pubmed:12361959(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:/1NFeFBg+2kIpzgPP76GaEbvDxU7227 rogid:Qg6n+kEKMAVdGsN57ZqHQKt0SRM7227 intact-crc:7D9D887A2254C575|rigid:Zm7XuW5RzzhqrTUXh9vsSYpHtnA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P23023 uniprotkb:P23023 intact:EBI-196709|uniprotkb:P23022|uniprotkb:Q0KIA7|uniprotkb:Q95TA5|uniprotkb:Q9VHY0|ensemblmetazoa:FBpp0081256|ensemblmetazoa:FBpp0303106 intact:EBI-196709|uniprotkb:P23022|uniprotkb:Q0KIA7|uniprotkb:Q95TA5|uniprotkb:Q9VHY0|ensemblmetazoa:FBpp0081256|ensemblmetazoa:FBpp0303106 psi-mi:dsx_drome(display_long)|uniprotkb:dsx(gene name)|psi-mi:dsx(display_short)|uniprotkb:CG11094(orf name) psi-mi:dsx_drome(display_long)|uniprotkb:dsx(gene name)|psi-mi:dsx(display_short)|uniprotkb:CG11094(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872650 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524272.4|refseq:NP_731197.1|refseq:NP_731198.1|flybase:FBgn0000504|refseq:NP_001287220.1|refseq:NP_001262352.1|dip:DIP-17110N|ensemblmetazoa:FBgn0000504(gene)|ensemblmetazoa:FBtr0081759(transcript)|ensemblmetazoa:FBtr0330073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007485"(imaginal disc-derived male genitalia development)|go:"GO:0007486"(imaginal disc-derived female genitalia development)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0007619"(courtship behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0018993"(somatic sex determination)|go:"GO:0019101"(female somatic sex determination)|go:"GO:0035215"(genital disc development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0045496"(male analia development)|go:"GO:0045497"(female analia development)|go:"GO:0045498"(sex comb development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046660"(female sex differentiation)|go:"GO:0046661"(male sex differentiation)|go:"GO:0048071"(sex-specific pigmentation)|go:"GO:0048086"(negative regulation of developmental pigmentation)|interpro:IPR001275(DM DNA-binding)|interpro:IPR014932(Doublesex dimerisation)|interpro:IPR026607|interpro:IPR036407|rcsb pdb:1LPV|rcsb pdb:1ZV1|rcsb pdb:2JZ0|rcsb pdb:2JZ1 refseq:NP_524272.4|refseq:NP_731197.1|refseq:NP_731198.1|flybase:FBgn0000504|refseq:NP_001287220.1|refseq:NP_001262352.1|dip:DIP-17110N|ensemblmetazoa:FBgn0000504(gene)|ensemblmetazoa:FBtr0081759(transcript)|ensemblmetazoa:FBtr0330073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007485"(imaginal disc-derived male genitalia development)|go:"GO:0007486"(imaginal disc-derived female genitalia development)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0007619"(courtship behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0018993"(somatic sex determination)|go:"GO:0019101"(female somatic sex determination)|go:"GO:0035215"(genital disc development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0045496"(male analia development)|go:"GO:0045497"(female analia development)|go:"GO:0045498"(sex comb development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046660"(female sex differentiation)|go:"GO:0046661"(male sex differentiation)|go:"GO:0048071"(sex-specific pigmentation)|go:"GO:0048086"(negative regulation of developmental pigmentation)|interpro:IPR001275(DM DNA-binding)|interpro:IPR014932(Doublesex dimerisation)|interpro:IPR026607|interpro:IPR036407|rcsb pdb:1LPV|rcsb pdb:1ZV1|rcsb pdb:2JZ0|rcsb pdb:2JZ1 pubmed:8978051(see-also)|pubmed:8649422(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Qg6n+kEKMAVdGsN57ZqHQKt0SRM7227 rogid:Qg6n+kEKMAVdGsN57ZqHQKt0SRM7227 intact-crc:4D6A482E7E9D8BD5|rigid:MemuXT5ZJMt/nrvR6BaPH2hzTjo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07207 uniprotkb:Q23985 intact:EBI-103438|uniprotkb:O97458|uniprotkb:P04154|uniprotkb:Q9W4T8|ensemblmetazoa:FBpp0070483|ensemblmetazoa:FBpp0293201 intact:EBI-190618|intact:EBI-1630243|uniprotkb:Q86P53|uniprotkb:Q9W3Z1|uniprotkb:A9YJA9|uniprotkb:A9YJB1|uniprotkb:A9YJB7|uniprotkb:B3LF71|ensemblmetazoa:FBpp0070876 psi-mi:notch_drome(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:CG3936(orf name) psi-mi:dtx_drome(display_long)|uniprotkb:dx(gene name)|psi-mi:dx(display_short)|uniprotkb:Probable E3 ubiquitin-protein ligase deltex(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase deltex(gene name synonym)|uniprotkb:CG3929(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872654 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476859.2|flybase:FBgn0004647|ensemblmetazoa:FBgn0004647(gene)|ensemblmetazoa:FBtr0070507(transcript)|ensemblmetazoa:FBtr0304659(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002213"(defense response to insect)|go:"GO:0003682"(chromatin binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007391"(dorsal closure)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009608"(response to symbiont)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0022416"(chaeta development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0007498"(mesoderm development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0007616"(long-term memory)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0040008"(regulation of growth)|go:"GO:0042686"(regulation of cardioblast cell fate specification)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045316"(negative regulation of compound eye photoreceptor development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048627"(myoblast development)|go:"GO:0048664"(neuron fate determination)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050699"(WW domain binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0060289"(compartment boundary maintenance)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990433"(CSL-Notch-Mastermind transcription factor complex)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1OT8|rcsb pdb:2JMF|refseq:NP_001245510.1|dip:DIP-5N refseq:NP_511064.2|flybase:FBgn0000524|dip:DIP-18159N|ensemblmetazoa:FBgn0000524(gene)|ensemblmetazoa:FBtr0070914(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0035220"(wing disc development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018123|interpro:IPR037197|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|rcsb pdb:2A90|reactome:R-DME-2122948|reactome:R-DME-983168 pubmed:11861487(see-also)|pubmed:8162848(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:T1iHJGMHXkhxbFRybmSDlizN7oQ7227 rogid:BROv2MEe94OPExr6R/P0jYwR7WY7227 intact-crc:3649EE53C303E5DA|rigid:p7wXGhJ96oL7pd7e5R8WGj8DkOg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10084 uniprotkb:P13098 intact:EBI-174136|intact:EBI-1639078|uniprotkb:O76890|uniprotkb:Q4V705|ensemblmetazoa:FBpp0070072 intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335 psi-mi:ast4_drome(display_long)|uniprotkb:sc(gene name)|psi-mi:sc(display_short)|uniprotkb:T4(gene name synonym)|uniprotkb:Protein scute(gene name synonym)|uniprotkb:sis-b(gene name synonym)|uniprotkb:CG3827(orf name) psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872658 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476803.1|flybase:FBgn0004170|dip:DIP-325N|ensemblmetazoa:FBgn0004170(gene)|ensemblmetazoa:FBtr0070073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638 refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:WTTmp3SuZ10YiZMKYALr68UiRO07227 rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227 intact-crc:E1409EE0479B50B8|rigid:IBH2xMvLv5eN/DpQtF6AsYpzwP4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P13097 uniprotkb:P13098 intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334 intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335 psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name) psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872670 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ko+76awzLWRJNBn06B3PQZWBhf47227 rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227 intact-crc:77AAFEEA60BFC6B8|rigid:gRy3QahZGWyRQ6e8lR05HlgmQAQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P13096 uniprotkb:P13098 intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352 intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335 psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name) psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872674 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227 rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227 intact-crc:B51F0F27026324FD|rigid:SDcf05o6jOS+n+F7l5xiudZtNII false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P29052 uniprotkb:Q27272 intact:EBI-107328|uniprotkb:Q6AWH9|uniprotkb:Q9VKV7|ensemblmetazoa:FBpp0079615|ensemblmetazoa:FBpp0305673 intact:EBI-174260|uniprotkb:Q95RJ4|uniprotkb:Q9VX16|ensemblmetazoa:FBpp0074237 psi-mi:tf2b_drome(display_long)|uniprotkb:General transcription factor TFIIB(gene name synonym)|uniprotkb:TfIIB(gene name)|psi-mi:TfIIB(display_short)|uniprotkb:CG5193(orf name) psi-mi:taf9_drome(display_long)|uniprotkb:"e(y)1"(gene name)|psi-mi:"e(y)1"(display_short)|uniprotkb:TAF40(gene name synonym)|uniprotkb:CG6474(orf name)|uniprotkb:Transcription initiation factor TFIID 42 kDa subunit(gene name synonym)|uniprotkb:TAFII40(gene name synonym)|uniprotkb:p42(gene name synonym)|uniprotkb:Protein enhancer of yellow 1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872678 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001260349.1|refseq:NP_476888.1|flybase:FBgn0004915|dip:DIP-17603N|ensemblmetazoa:FBgn0004915(gene)|ensemblmetazoa:FBtr0080025(transcript)|ensemblmetazoa:FBtr0333489(transcript)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0070897"(transcription preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR000812(Transcription factor TFIIB related)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR013150(Transcription factor TFIIB, cyclin-related)|interpro:IPR013763(Cyclin-related)|interpro:IPR023486|interpro:IPR036915|reactome:R-DME-674695|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 refseq:NP_523391.3|flybase:FBgn0000617|dip:DIP-239N|ensemblmetazoa:FBgn0000617(gene)|ensemblmetazoa:FBtr0074463(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|rcsb pdb:1TAF|reactome:R-DME-5689880|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 pubmed:8221891(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:elkTGn4p1gaBf5tseVuCRdSz4aM7227 rogid:MB1JQfTIG1nLfK/apoLrr6GHKNU7227 intact-crc:5F3308618B534DEC|rigid:IJCs+pxihaC02nfbs7L38qfcbF4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P49847 uniprotkb:Q27272 intact:EBI-136204|uniprotkb:Q9VW16|uniprotkb:Q961B6|ensemblmetazoa:FBpp0074709 intact:EBI-174260|uniprotkb:Q95RJ4|uniprotkb:Q9VX16|ensemblmetazoa:FBpp0074237 psi-mi:taf6_drome(display_long)|uniprotkb:Taf6(gene name)|psi-mi:Taf6(display_short)|uniprotkb:Taf60(gene name synonym)|uniprotkb:CG32211(orf name)|uniprotkb:Transcription initiation factor TFIID 62 kDa subunit(gene name synonym)|uniprotkb:TAFII-60(gene name synonym)|uniprotkb:TAFII-62(gene name synonym) psi-mi:taf9_drome(display_long)|uniprotkb:"e(y)1"(gene name)|psi-mi:"e(y)1"(display_short)|uniprotkb:TAF40(gene name synonym)|uniprotkb:CG6474(orf name)|uniprotkb:Transcription initiation factor TFIID 42 kDa subunit(gene name synonym)|uniprotkb:TAFII40(gene name synonym)|uniprotkb:p42(gene name synonym)|uniprotkb:Protein enhancer of yellow 1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872682 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524161.2|flybase:FBgn0010417|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR011442(Protein of unknown function DUF1546)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037796|rcsb pdb:1TAF|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|ensemblmetazoa:FBgn0010417(gene)|ensemblmetazoa:FBtr0074941(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|dip:DIP-778N refseq:NP_523391.3|flybase:FBgn0000617|dip:DIP-239N|ensemblmetazoa:FBgn0000617(gene)|ensemblmetazoa:FBtr0074463(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|rcsb pdb:1TAF|reactome:R-DME-5689880|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 pubmed:8262073(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:B6rVKKVnmMjwbfPHdfjlEg2QdHs7227 rogid:MB1JQfTIG1nLfK/apoLrr6GHKNU7227 intact-crc:CF0B3BC97FA6CB4B|rigid:bDN+IsSAc3+FDWUr56vzOx15RPc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24472 uniprotkb:Q27368 intact:EBI-145741|uniprotkb:O77272|uniprotkb:Q961U8|ensemblmetazoa:FBpp0070141 intact:EBI-108384|uniprotkb:O77035|uniprotkb:Q5U0Z6|ensemblmetazoa:FBpp0083516|ensemblmetazoa:FBpp0083517|ensemblmetazoa:FBpp0083518|ensemblmetazoa:FBpp0311985 psi-mi:rbf_drome(display_long)|uniprotkb:Rbf(gene name)|psi-mi:Rbf(display_short)|uniprotkb:CG7413(orf name) psi-mi:e2f1_drome(display_long)|uniprotkb:E2f1(gene name)|psi-mi:E2f1(display_short)|uniprotkb:E2f(gene name synonym)|uniprotkb:dE2F(gene name synonym)|uniprotkb:CG6376(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872686 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525036.2|flybase:FBgn0015799|dip:DIP-34025N|ensemblmetazoa:FBgn0015799(gene)|ensemblmetazoa:FBtr0070146(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007113"(endomitotic cell cycle)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008361"(regulation of cell size)|reactome:R-DME-69231|reactome:R-DME-2173796|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0030154"(cell differentiation)|go:"GO:0031523"(Myb complex)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042594"(response to starvation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:1900117"(regulation of execution phase of apoptosis)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|reactome:R-DME-1538133|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage) refseq:NP_524437.2|refseq:NP_732646.1|refseq:NP_732647.1|flybase:FBgn0011766|refseq:NP_001287455.1|dip:DIP-21076N|ensemblmetazoa:FBgn0011766(gene)|ensemblmetazoa:FBtr0084117(transcript)|ensemblmetazoa:FBtr0084118(transcript)|ensemblmetazoa:FBtr0084119(transcript)|ensemblmetazoa:FBtr0346157(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0007419"(ventral cord development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045850"(positive regulation of nurse cell apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900117"(regulation of execution phase of apoptosis)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|reactome:R-DME-68689|reactome:R-DME-68911|reactome:R-DME-8953750 pubmed:12234932(see-also)|pubmed:8675008(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Z0pdwbec8RKtU9vh7XTH1yrBrHs7227 rogid:iuWAVrB7ugwrZPPrJbYLNhkvS2A7227 intact-crc:8FC77D8328C77323|rigid:SLEvhuFjXGdMXZb5+YaNcZ2mhfw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O77051 uniprotkb:Q27368 intact:EBI-93258|ensemblmetazoa:FBpp0081029|ensemblmetazoa:FBpp0312101 intact:EBI-108384|uniprotkb:O77035|uniprotkb:Q5U0Z6|ensemblmetazoa:FBpp0083516|ensemblmetazoa:FBpp0083517|ensemblmetazoa:FBpp0083518|ensemblmetazoa:FBpp0311985 psi-mi:e2f2_drome(display_long)|uniprotkb:E2f2(gene name)|psi-mi:E2f2(display_short)|uniprotkb:E2F transcription factor 2(gene name synonym)|uniprotkb:E2F-like transcription factor E2F2(gene name synonym)|uniprotkb:CG1071(orf name) psi-mi:e2f1_drome(display_long)|uniprotkb:E2f1(gene name)|psi-mi:E2f1(display_short)|uniprotkb:E2f(gene name synonym)|uniprotkb:dE2F(gene name synonym)|uniprotkb:CG6376(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872690 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477355.1|flybase:FBgn0024371|refseq:NP_001286115.1|go:"GO:0048477"(oogenesis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|reactome:R-DME-1538133|reactome:R-DME-2173796|reactome:R-DME-69231|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensemblmetazoa:FBgn0024371(gene)|ensemblmetazoa:FBtr0081501(transcript)|ensemblmetazoa:FBtr0346451(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007113"(endomitotic cell cycle)|go:"GO:0007444"(imaginal disc development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031523"(Myb complex)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|dip:DIP-18289N refseq:NP_524437.2|refseq:NP_732646.1|refseq:NP_732647.1|flybase:FBgn0011766|refseq:NP_001287455.1|dip:DIP-21076N|ensemblmetazoa:FBgn0011766(gene)|ensemblmetazoa:FBtr0084117(transcript)|ensemblmetazoa:FBtr0084118(transcript)|ensemblmetazoa:FBtr0084119(transcript)|ensemblmetazoa:FBtr0346157(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0007419"(ventral cord development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045850"(positive regulation of nurse cell apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900117"(regulation of execution phase of apoptosis)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|reactome:R-DME-68689|reactome:R-DME-68911|reactome:R-DME-8953750 pubmed:11511545(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:z60gPktDWudv7yxPjh6tUkX4s+g7227 rogid:iuWAVrB7ugwrZPPrJbYLNhkvS2A7227 intact-crc:07962E12386CEF67|rigid:dh7+0elK5+YvDB+rY3RYTsltA4c false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9NIS1 uniprotkb:O77051 intact:EBI-869347 intact:EBI-93258|ensemblmetazoa:FBpp0081029|ensemblmetazoa:FBpp0312101 psi-mi:q9nis1_drome(display_long)|uniprotkb:Rbf2(gene name)|psi-mi:Rbf2(display_short)|uniprotkb:CG5083(orf name) psi-mi:e2f2_drome(display_long)|uniprotkb:E2f2(gene name)|psi-mi:E2f2(display_short)|uniprotkb:E2F transcription factor 2(gene name synonym)|uniprotkb:E2F-like transcription factor E2F2(gene name synonym)|uniprotkb:CG1071(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872694 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0038390|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031523"(Myb complex)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915 refseq:NP_477355.1|flybase:FBgn0024371|refseq:NP_001286115.1|go:"GO:0048477"(oogenesis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|reactome:R-DME-1538133|reactome:R-DME-2173796|reactome:R-DME-69231|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensemblmetazoa:FBgn0024371(gene)|ensemblmetazoa:FBtr0081501(transcript)|ensemblmetazoa:FBtr0346451(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007113"(endomitotic cell cycle)|go:"GO:0007444"(imaginal disc development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031523"(Myb complex)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|dip:DIP-18289N pubmed:12234932(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xrrnqLg4IfpuNtU+/bGNK6cFLlI7227 rogid:z60gPktDWudv7yxPjh6tUkX4s+g7227 intact-crc:259C029CDB856B25|rigid:Q9KlM7AlOSFvk+a/D2JPk4ogG4Q false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P13582 uniprotkb:P48607 intact:EBI-91434|uniprotkb:Q9VF90|ensemblmetazoa:FBpp0082539 intact:EBI-261915|uniprotkb:Q95SU5|uniprotkb:Q9VB84|ensemblmetazoa:FBpp0084507 psi-mi:east_drome(display_long)|uniprotkb:ea(gene name)|psi-mi:ea(display_short)|uniprotkb:CG4920(orf name) psi-mi:spz_drome(display_long)|uniprotkb:spz(gene name)|psi-mi:spz(display_short)|uniprotkb:CG6134(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872698 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524362.2|flybase:FBgn0000533|ensemblmetazoa:FBgn0000533(gene)|interpro:IPR043504|reactome:R-DME-1592389|reactome:R-DME-209442|ensemblmetazoa:FBtr0083083(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007311"(maternal specification of dorsal/ventral axis, oocyte, germ-line encoded)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0098595"(perivitelline space)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR022700|interpro:IPR033116|interpro:IPR038565|dip:DIP-18843N refseq:NP_524526.1|refseq:NP_733188.1|refseq:NP_733191.1|refseq:NP_733194.1|refseq:NP_733195.1|flybase:FBgn0003495|dip:DIP-23237N|ensemblmetazoa:FBgn0003495(gene)|ensemblmetazoa:FBtr0085137(transcript)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002347"(response to tumor cell)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0002807"(positive regulation of antimicrobial peptide biosynthetic process)|go:"GO:0005121"(Toll binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0006967"(positive regulation of antifungal peptide biosynthetic process)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0008083"(growth factor activity)|go:"GO:0008592"(regulation of Toll signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021556"(central nervous system formation)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061760"(antifungal innate immune response)|interpro:IPR029034|interpro:IPR032104|rcsb pdb:3E07|rcsb pdb:4BV4|rcsb pdb:4LXR|rcsb pdb:4LXS|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874 pubmed:9533958(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:2dHOSJXgbcDiM1kzzfqIzxmbNrA7227 rogid:odMgEmovtblzFvylNYMuYbP6ODE7227 intact-crc:ADAE4EB6062AEA45|rigid:t/N99hfBFyhhvL/xASUtaYKTUUY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P05049 uniprotkb:P13582 intact:EBI-82507|uniprotkb:Q29QH0|uniprotkb:Q9VFZ7|ensemblmetazoa:FBpp0082184|ensemblmetazoa:FBpp0111746 intact:EBI-91434|uniprotkb:Q9VF90|ensemblmetazoa:FBpp0082539 psi-mi:snak_drome(display_long)|uniprotkb:snk(gene name)|psi-mi:snk(display_short)|uniprotkb:CG7996(orf name) psi-mi:east_drome(display_long)|uniprotkb:ea(gene name)|psi-mi:ea(display_short)|uniprotkb:CG4920(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872702 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097766.1|refseq:NP_524338.2|flybase:FBgn0003450|ensemblmetazoa:FBgn0003450(gene)|ensemblmetazoa:FBtr0082716(transcript)|ensemblmetazoa:FBtr0112833(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0031638"(zymogen activation)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR022700|interpro:IPR033116|interpro:IPR043504|reactome:R-DME-209442 refseq:NP_524362.2|flybase:FBgn0000533|ensemblmetazoa:FBgn0000533(gene)|interpro:IPR043504|reactome:R-DME-1592389|reactome:R-DME-209442|ensemblmetazoa:FBtr0083083(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007311"(maternal specification of dorsal/ventral axis, oocyte, germ-line encoded)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0098595"(perivitelline space)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR022700|interpro:IPR033116|interpro:IPR038565|dip:DIP-18843N pubmed:11296245(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:p90dDWv07u/IMHJwjtSeNT5pwuE7227 rogid:2dHOSJXgbcDiM1kzzfqIzxmbNrA7227 intact-crc:CF9CA5943ED34D1C|rigid:sKV2IRxMQDG0Ieu4TPY0zHXj7BE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O62589 uniprotkb:P13582 intact:EBI-115952|ensemblmetazoa:FBpp0304588|uniprotkb:D9PTR2|uniprotkb:M9PEE0|uniprotkb:M9PGY7|uniprotkb:M9PJK1|uniprotkb:Q1EC38 intact:EBI-91434|uniprotkb:Q9VF90|ensemblmetazoa:FBpp0082539 psi-mi:gd_drome(display_long)|uniprotkb:gd(gene name)|psi-mi:gd(display_short)|uniprotkb:CG1505(orf name)|uniprotkb:Protein gastrulation defective(gene name synonym) psi-mi:east_drome(display_long)|uniprotkb:ea(gene name)|psi-mi:ea(display_short)|uniprotkb:CG4920(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872706 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0000808|ensemblmetazoa:FBgn0000808(gene)|ensemblmetazoa:FBtr0332309(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031638"(zymogen activation)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0098595"(perivitelline space)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR031986|interpro:IPR043504|reactome:R-DME-209442|refseq:NP_001303552.1|refseq:NP_001259478.1|refseq:NP_001259479.1|refseq:NP_001259480.1 refseq:NP_524362.2|flybase:FBgn0000533|ensemblmetazoa:FBgn0000533(gene)|interpro:IPR043504|reactome:R-DME-1592389|reactome:R-DME-209442|ensemblmetazoa:FBtr0083083(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007311"(maternal specification of dorsal/ventral axis, oocyte, germ-line encoded)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0098595"(perivitelline space)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR022700|interpro:IPR033116|interpro:IPR038565|dip:DIP-18843N pubmed:11350927(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:7JiWN5uFENDvUOzB+akqxyqYmRM7227 rogid:2dHOSJXgbcDiM1kzzfqIzxmbNrA7227 intact-crc:AFD703B840BF2CCE|rigid:JDIcRu+vyys7ZU/6B2fw6MeXby8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24052 uniprotkb:Q02280 intact:EBI-498048 intact:EBI-85304|uniprotkb:Q9VXZ6|ensemblmetazoa:FBpp0073772 psi-mi:q24052_drome(display_long)|uniprotkb:Hk(gene name)|psi-mi:Hk(display_short)|uniprotkb:CG43388(orf name) psi-mi:kcnae_drome(display_long)|uniprotkb:eag(gene name)|psi-mi:eag(display_short)|uniprotkb:Ether-a-go-go protein(gene name synonym)|uniprotkb:CG10952(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872710 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0263220|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0050802"(circadian sleep/wake cycle, sleep)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1903818"(positive regulation of voltage-gated potassium channel activity)|interpro:IPR005399(Potassium channel, voltage-dependent, beta subunit, KCNAB-related)|interpro:IPR005983(Potassium channel, voltage-dependent, beta subunit, KCNAB)|interpro:IPR023210|interpro:IPR036812 refseq:NP_511158.2|flybase:FBgn0000535|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003949(Potassium channel, voltage-dependent, EAG)|interpro:IPR005821(Ion transport)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR035965|rcsb pdb:5FG8|rcsb pdb:5H9B|rcsb pdb:5HU3|reactome:R-DME-1296072|go:"GO:1903818"(positive regulation of voltage-gated potassium channel activity)|interpro:IPR000014(PAS)|ensemblmetazoa:FBgn0000535(gene)|ensemblmetazoa:FBtr0073955(transcript)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007619"(courtship behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0042066"(perineurial glial growth)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048150"(behavioral response to ether)|go:"GO:0071805"(potassium ion transmembrane transport) pubmed:9497369(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:MnNQ2sop2YJt4GWP9KoJOPrwQXw7227 rogid:NuiW+3la4tADV2Y5NCK6/F1Wlxg7227 intact-crc:894D218C9A64C1FC|rigid:uS6D7jgeGPQwXbQQxMGdcO5iU64 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20153 uniprotkb:P34021 intact:EBI-149021|uniprotkb:Q9W535|ensemblmetazoa:FBpp0070332|ensemblmetazoa:FBpp0305937 intact:EBI-251199|intact:EBI-1627522|uniprotkb:Q0E9N8|uniprotkb:Q6AWL4|uniprotkb:Q8SY10|uniprotkb:Q95TS4|uniprotkb:Q9V9K8|ensemblmetazoa:FBpp0085352|ensemblmetazoa:FBpp0291631 psi-mi:usp_drome(display_long)|uniprotkb:usp(gene name)|psi-mi:usp(display_short)|uniprotkb:Cf1(gene name synonym)|uniprotkb:NR2B4(gene name synonym)|uniprotkb:CG4380(orf name)|uniprotkb:XR2C(gene name synonym)|uniprotkb:Chorion factor 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 4(gene name synonym) psi-mi:ecr_drome(display_long)|uniprotkb:EcR(gene name)|psi-mi:EcR(display_short)|uniprotkb:NR1H1(gene name synonym)|uniprotkb:CG1765(orf name)|uniprotkb:Ecdysteroid receptor(gene name synonym)|uniprotkb:20-hydroxy-ecdysone receptor(gene name synonym)|uniprotkb:EcRH(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872714 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476781.1|flybase:FBgn0003964|refseq:NP_001259168.1|dip:DIP-645N|ensemblmetazoa:FBgn0003964(gene)|ensemblmetazoa:FBtr0070346(transcript)|ensemblmetazoa:FBtr0333803(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|reactome:R-DME-9707564|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006697"(ecdysone biosynthetic process)|go:"GO:0007281"(germ cell development)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007552"(metamorphosis)|go:"GO:0008230"(ecdysone receptor holocomplex)|reactome:R-DME-9623433|go:"GO:0008232"(activator ecdysone receptor complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016319"(mushroom body development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0035073"(pupariation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0042562"(hormone binding)|go:"GO:0042594"(response to starvation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071390"(cellular response to ecdysone)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1HG4|rcsb pdb:1R0O|rcsb pdb:2HAN|reactome:R-DME-159418|reactome:R-DME-200425|reactome:R-DME-204174|reactome:R-DME-381340|reactome:R-DME-383280|reactome:R-DME-400206|reactome:R-DME-5362517|reactome:R-DME-9029569|reactome:R-DME-9616222 refseq:NP_001163061.1|refseq:NP_724456.1|refseq:NP_724457.1|refseq:NP_724458.1|refseq:NP_724459.1|refseq:NP_724460.1|flybase:FBgn0000546|dip:DIP-158N|ensemblmetazoa:FBgn0000546(gene)|ensemblmetazoa:FBtr0086011(transcript)|ensemblmetazoa:FBtr0302439(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002164"(larval development)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007281"(germ cell development)|go:"GO:0007291"(sperm individualization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007552"(metamorphosis)|go:"GO:0007616"(long-term memory)|go:"GO:0008230"(ecdysone receptor holocomplex)|go:"GO:0008231"(repressor ecdysone receptor complex)|go:"GO:0008232"(activator ecdysone receptor complex)|go:"GO:0008258"(head involution)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008362"(chitin-based embryonic cuticle biosynthetic process)|go:"GO:0008544"(epidermis development)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016319"(mushroom body development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0018990"(ecdysis, chitin-based cuticle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0035053"(dorsal vessel heart proper cell fate commitment)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035073"(pupariation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035076"(ecdysone receptor-mediated signaling pathway)|go:"GO:0035100"(ecdysone binding)|go:"GO:0035180"(larval wandering behavior)|go:"GO:0035188"(hatching)|go:"GO:0035193"(larval central nervous system remodeling)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035297"(regulation of Malpighian tubule diameter)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0042220"(response to cocaine)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904799"(regulation of neuron remodeling)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003069(Ecdysteroid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR041889|rcsb pdb:1R0N|rcsb pdb:1R0O|rcsb pdb:2HAN|reactome:R-DME-159418|reactome:R-DME-383280|reactome:R-DME-4090294|reactome:R-DME-9029569|reactome:R-DME-9623433 pubmed:7882975(see-also)|pubmed:8247157(see-also)|pubmed:8385270(see-also)|pubmed:12084064(see-also)|pubmed:1327536(see-also)|pubmed:7729584(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:amASW54ZH6dtdZULbgr9lt4GbBE7227 rogid:0BpOr5B3E7+KCZaSBnNEGFjfBYI7227 intact-crc:2CFDDE334783D1B1|rigid:dG8Q1nSQxASfPu0YYRd76Y2RbTI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q95RS0 uniprotkb:P34021 intact:EBI-869358 intact:EBI-251199|intact:EBI-1627522|uniprotkb:Q0E9N8|uniprotkb:Q6AWL4|uniprotkb:Q8SY10|uniprotkb:Q95TS4|uniprotkb:Q9V9K8|ensemblmetazoa:FBpp0085352|ensemblmetazoa:FBpp0291631 psi-mi:q95rs0_drome(display_long)|uniprotkb:Smr(gene name)|psi-mi:Smr(display_short)|uniprotkb:CG4013(orf name) psi-mi:ecr_drome(display_long)|uniprotkb:EcR(gene name)|psi-mi:EcR(display_short)|uniprotkb:NR1H1(gene name synonym)|uniprotkb:CG1765(orf name)|uniprotkb:Ecdysteroid receptor(gene name synonym)|uniprotkb:20-hydroxy-ecdysone receptor(gene name synonym)|uniprotkb:EcRH(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872718 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0265523|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0042826"(histone deacetylase binding) refseq:NP_001163061.1|refseq:NP_724456.1|refseq:NP_724457.1|refseq:NP_724458.1|refseq:NP_724459.1|refseq:NP_724460.1|flybase:FBgn0000546|dip:DIP-158N|ensemblmetazoa:FBgn0000546(gene)|ensemblmetazoa:FBtr0086011(transcript)|ensemblmetazoa:FBtr0302439(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002164"(larval development)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007281"(germ cell development)|go:"GO:0007291"(sperm individualization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007552"(metamorphosis)|go:"GO:0007616"(long-term memory)|go:"GO:0008230"(ecdysone receptor holocomplex)|go:"GO:0008231"(repressor ecdysone receptor complex)|go:"GO:0008232"(activator ecdysone receptor complex)|go:"GO:0008258"(head involution)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008362"(chitin-based embryonic cuticle biosynthetic process)|go:"GO:0008544"(epidermis development)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016319"(mushroom body development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0018990"(ecdysis, chitin-based cuticle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0035053"(dorsal vessel heart proper cell fate commitment)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035073"(pupariation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035076"(ecdysone receptor-mediated signaling pathway)|go:"GO:0035100"(ecdysone binding)|go:"GO:0035180"(larval wandering behavior)|go:"GO:0035188"(hatching)|go:"GO:0035193"(larval central nervous system remodeling)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035297"(regulation of Malpighian tubule diameter)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0042220"(response to cocaine)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904799"(regulation of neuron remodeling)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003069(Ecdysteroid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR041889|rcsb pdb:1R0N|rcsb pdb:1R0O|rcsb pdb:2HAN|reactome:R-DME-159418|reactome:R-DME-383280|reactome:R-DME-4090294|reactome:R-DME-9029569|reactome:R-DME-9623433 pubmed:10488333(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:o8+vwhYspxfL0sTV2NiKCmIe1Jk7227 rogid:0BpOr5B3E7+KCZaSBnNEGFjfBYI7227 intact-crc:861AC229A3D52F82|rigid:3LJV22YKo0S9n58kbtol54hOapQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O44382 uniprotkb:P25867 intact:EBI-869364 intact:EBI-196394|uniprotkb:Q9VFG6|ensemblmetazoa:FBpp0082477|ensemblmetazoa:FBpp0302691|ensemblmetazoa:FBpp0307824 psi-mi:o44382_drome(display_long)|uniprotkb:slmb(gene name)|psi-mi:slmb(display_short)|uniprotkb:slimb(gene name synonym)|uniprotkb:CG3412(orf name) psi-mi:ubcd1_drome(display_long)|uniprotkb:eff(gene name)|psi-mi:eff(display_short)|uniprotkb:UbcD1(gene name synonym)|uniprotkb:CG7425(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Protein effete(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872722 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283468|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-432524 refseq:NP_001262578.1|refseq:NP_001262579.1|refseq:NP_731941.1|flybase:FBgn0011217|dip:DIP-18953N|ensemblmetazoa:FBgn0011217(gene)|ensemblmetazoa:FBtr0083018(transcript)|ensemblmetazoa:FBtr0310554(transcript)|ensemblmetazoa:FBtr0336876(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0051276"(chromosome organization)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0097039"(protein linear polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-1234176|reactome:R-DME-141430|reactome:R-DME-174048|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-176407|reactome:R-DME-176408|reactome:R-DME-176409|reactome:R-DME-176412|reactome:R-DME-179409|reactome:R-DME-201451|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-2559582|reactome:R-DME-5689896|reactome:R-DME-69017|reactome:R-DME-8866652|reactome:R-DME-8866654|reactome:R-DME-8951664|reactome:R-DME-9033241|reactome:R-DME-983168 pubmed:11500045(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:hKsZL6X4sxi/Zu4RDHlAV5IoZ2o7227 rogid:m591n40BVy1LgRJXj1+X1FvIbzc7227 intact-crc:07753866828F2F68|rigid:R+MtJl7b6YaqvYZ+xkmE+KMjQu0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24311 uniprotkb:P25867 intact:EBI-136038|uniprotkb:A4UZ78|ensemblmetazoa:FBpp0087921|ensemblmetazoa:FBpp0087922|ensemblmetazoa:FBpp0087923|ensemblmetazoa:FBpp0087924|uniprotkb:Q0E9G0|uniprotkb:Q9V312 intact:EBI-196394|uniprotkb:Q9VFG6|ensemblmetazoa:FBpp0082477|ensemblmetazoa:FBpp0302691|ensemblmetazoa:FBpp0307824 psi-mi:cul1_drome(display_long)|uniprotkb:Cul1(gene name)|psi-mi:Cul1(display_short)|uniprotkb:Lin-19 homolog protein(gene name synonym)|uniprotkb:cul-1(gene name synonym)|uniprotkb:lin19(gene name synonym)|uniprotkb:CG1877(orf name) psi-mi:ubcd1_drome(display_long)|uniprotkb:eff(gene name)|psi-mi:eff(display_short)|uniprotkb:UbcD1(gene name synonym)|uniprotkb:CG7425(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Protein effete(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872726 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523655.1|refseq:NP_724621.1|refseq:NP_724622.1|refseq:NP_724623.1|flybase:FBgn0015509|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904801"(positive regulation of neuron remodeling)|ensemblmetazoa:FBgn0015509(gene)|ensemblmetazoa:FBtr0088845(transcript)|ensemblmetazoa:FBtr0088846(transcript)|ensemblmetazoa:FBtr0088847(transcript)|ensemblmetazoa:FBtr0088848(transcript)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q24311|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168|dip:DIP-19461N refseq:NP_001262578.1|refseq:NP_001262579.1|refseq:NP_731941.1|flybase:FBgn0011217|dip:DIP-18953N|ensemblmetazoa:FBgn0011217(gene)|ensemblmetazoa:FBtr0083018(transcript)|ensemblmetazoa:FBtr0310554(transcript)|ensemblmetazoa:FBtr0336876(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0051276"(chromosome organization)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0097039"(protein linear polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-1234176|reactome:R-DME-141430|reactome:R-DME-174048|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-176407|reactome:R-DME-176408|reactome:R-DME-176409|reactome:R-DME-176412|reactome:R-DME-179409|reactome:R-DME-201451|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-2559582|reactome:R-DME-5689896|reactome:R-DME-69017|reactome:R-DME-8866652|reactome:R-DME-8866654|reactome:R-DME-8951664|reactome:R-DME-9033241|reactome:R-DME-983168 pubmed:11500045(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:uik6AV9MpfMBKBZoYZSxvCl5bTc7227 rogid:m591n40BVy1LgRJXj1+X1FvIbzc7227 intact-crc:7BD6AF20CCE30EFC|rigid:w0ne1s20Gcf/Q4Q2CO/CpPNw83E false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P04412 uniprotkb:Q94918 intact:EBI-197863|uniprotkb:O18370|uniprotkb:O61601|uniprotkb:P81868|uniprotkb:Q9W2G0|ensemblmetazoa:FBpp0071571 intact:EBI-869384|uniprotkb:Q9VRQ3|ensemblmetazoa:FBpp0076790 psi-mi:egfr_drome(display_long)|uniprotkb:Egfr(gene name)|psi-mi:Egfr(display_short)|uniprotkb:top(gene name synonym)|uniprotkb:DER(gene name synonym)|uniprotkb:c-erbB(gene name synonym)|uniprotkb:CG10079(orf name)|uniprotkb:Gurken receptor(gene name synonym)|uniprotkb:Protein torpedo(gene name synonym)|uniprotkb:Drosophila relative of ERBB(gene name synonym) psi-mi:vein_drome(display_long)|uniprotkb:Epidermal growth factor-like protein(gene name synonym)|uniprotkb:Protein defective dorsal discs(gene name synonym)|uniprotkb:vn(gene name)|psi-mi:vn(display_short)|uniprotkb:ddd(gene name synonym)|uniprotkb:CG10491(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872730 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476759.1|flybase:FBgn0003731|dip:DIP-17316N|ensemblmetazoa:FBgn0003731(gene)|ensemblmetazoa:FBtr0071654(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003015"(heart process)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007431"(salivary gland development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007477"(notum development)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007482"(haltere development)|go:"GO:0008071"(maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008355"(olfactory learning)|go:"GO:0008406"(gonad development)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0022008"(neurogenesis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035310"(notum cell fate specification)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|mint:P04412|rcsb pdb:3I2T|rcsb pdb:3LTF|rcsb pdb:3LTG|reactome:R-DME-1227986|reactome:R-DME-1250196|reactome:R-DME-1251985|reactome:R-DME-1253288|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-177929|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-1963642|reactome:R-DME-212718|reactome:R-DME-2179392|reactome:R-DME-416572|reactome:R-DME-5673001|reactome:R-DME-6785631|reactome:R-DME-6811558|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-9018519|reactome:R-DME-9652282 refseq:NP_523942.2|flybase:FBgn0003984|ensemblmetazoa:FBgn0003984(gene)|ensemblmetazoa:FBtr0077082(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007477"(notum development)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007482"(haltere development)|go:"GO:0007494"(midgut development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0035310"(notum cell fate specification)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048513"(animal organ development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040180 pubmed:10349622(see-also)|pubmed:9334331(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Ae9kedh1v+TZ5zG4QorNPm9/FgA7227 rogid:NkLTC71WZ3fPunYHAmnJnWzjeNg7227 intact-crc:FB90464C9DA53312|rigid:1pVoyYlF73w84QiUj8c7oIyhOTw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O44783 uniprotkb:P04412 intact:EBI-132097|uniprotkb:A4V1F3|uniprotkb:Q6AWR4|uniprotkb:Q9VZP7|ensemblmetazoa:FBpp0073004|ensemblmetazoa:FBpp0073005 intact:EBI-197863|uniprotkb:O18370|uniprotkb:O61601|uniprotkb:P81868|uniprotkb:Q9W2G0|ensemblmetazoa:FBpp0071571 psi-mi:spy_drome(display_long)|uniprotkb:sty(gene name)|psi-mi:sty(display_short)|uniprotkb:CG1921(orf name) psi-mi:egfr_drome(display_long)|uniprotkb:Egfr(gene name)|psi-mi:Egfr(display_short)|uniprotkb:top(gene name synonym)|uniprotkb:DER(gene name synonym)|uniprotkb:c-erbB(gene name synonym)|uniprotkb:CG10079(orf name)|uniprotkb:Gurken receptor(gene name synonym)|uniprotkb:Protein torpedo(gene name synonym)|uniprotkb:Drosophila relative of ERBB(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872734 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523902.2|refseq:NP_728881.1|flybase:FBgn0014388|ensemblmetazoa:FBgn0014388(gene)|ensemblmetazoa:FBtr0073145(transcript)|ensemblmetazoa:FBtr0073146(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0021782"(glial cell development)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045314"(regulation of compound eye photoreceptor development)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0055001"(muscle cell development)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0110109"(negative regulation of imaginal disc-derived wing vein specification)|interpro:IPR007875(Sprouty)|reactome:R-DME-1295596|reactome:R-DME-182971|go:"GO:0120177"(negative regulation of torso signaling pathway)|dip:DIP-17914N refseq:NP_476759.1|flybase:FBgn0003731|dip:DIP-17316N|ensemblmetazoa:FBgn0003731(gene)|ensemblmetazoa:FBtr0071654(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003015"(heart process)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007431"(salivary gland development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007477"(notum development)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007482"(haltere development)|go:"GO:0008071"(maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008355"(olfactory learning)|go:"GO:0008406"(gonad development)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0022008"(neurogenesis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035310"(notum cell fate specification)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|mint:P04412|rcsb pdb:3I2T|rcsb pdb:3LTF|rcsb pdb:3LTG|reactome:R-DME-1227986|reactome:R-DME-1250196|reactome:R-DME-1251985|reactome:R-DME-1253288|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-177929|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-1963642|reactome:R-DME-212718|reactome:R-DME-2179392|reactome:R-DME-416572|reactome:R-DME-5673001|reactome:R-DME-6785631|reactome:R-DME-6811558|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-9018519|reactome:R-DME-9652282 pubmed:10457022(see-also)|pubmed:10226010(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Epk95p/MSvHN+VVqzKqaTdmoO6g7227 rogid:Ae9kedh1v+TZ5zG4QorNPm9/FgA7227 intact-crc:293A8E58715DAD2C|rigid:OiM6ReNfz/YXwRq6Z8Dfkv0gpkA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q01083 uniprotkb:P04412 intact:EBI-91342|ensemblmetazoa:FBpp0080808|ensemblmetazoa:FBpp0080809|ensemblmetazoa:FBpp0080810|ensemblmetazoa:FBpp0080811|ensemblmetazoa:FBpp0100054|uniprotkb:Q8SXE0|uniprotkb:Q9VIT4 intact:EBI-197863|uniprotkb:O18370|uniprotkb:O61601|uniprotkb:P81868|uniprotkb:Q9W2G0|ensemblmetazoa:FBpp0071571 psi-mi:spitz_drome(display_long)|uniprotkb:spi(gene name)|psi-mi:spi(display_short)|uniprotkb:CG10334(orf name) psi-mi:egfr_drome(display_long)|uniprotkb:Egfr(gene name)|psi-mi:Egfr(display_short)|uniprotkb:top(gene name synonym)|uniprotkb:DER(gene name synonym)|uniprotkb:c-erbB(gene name synonym)|uniprotkb:CG10079(orf name)|uniprotkb:Gurken receptor(gene name synonym)|uniprotkb:Protein torpedo(gene name synonym)|uniprotkb:Drosophila relative of ERBB(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872738 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005789"(endoplasmic reticulum membrane)|ensemblmetazoa:FBgn0005672(gene)|ensemblmetazoa:FBtr0081267(transcript)|ensemblmetazoa:FBtr0081268(transcript)|ensemblmetazoa:FBtr0081269(transcript)|ensemblmetazoa:FBtr0081270(transcript)|ensemblmetazoa:FBtr0100597(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001713"(ectodermal cell fate determination)|go:"GO:0003015"(heart process)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001027281.1|refseq:NP_476909.2|refseq:NP_599118.2|refseq:NP_599119.2|refseq:NP_599120.2|flybase:FBgn0005672|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007421"(stomatogastric nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:3C9A|rcsb pdb:3CA7|rcsb pdb:3LTF|rcsb pdb:3LTG|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|dip:DIP-18037N refseq:NP_476759.1|flybase:FBgn0003731|dip:DIP-17316N|ensemblmetazoa:FBgn0003731(gene)|ensemblmetazoa:FBtr0071654(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003015"(heart process)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007431"(salivary gland development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007477"(notum development)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007482"(haltere development)|go:"GO:0008071"(maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008355"(olfactory learning)|go:"GO:0008406"(gonad development)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0022008"(neurogenesis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035310"(notum cell fate specification)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|mint:P04412|rcsb pdb:3I2T|rcsb pdb:3LTF|rcsb pdb:3LTG|reactome:R-DME-1227986|reactome:R-DME-1250196|reactome:R-DME-1251985|reactome:R-DME-1253288|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-177929|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-1963642|reactome:R-DME-212718|reactome:R-DME-2179392|reactome:R-DME-416572|reactome:R-DME-5673001|reactome:R-DME-6785631|reactome:R-DME-6811558|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-9018519|reactome:R-DME-9652282 pubmed:10556052(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:RO8D5JspHbtNUFx11JHFCoUuv0A7227 rogid:Ae9kedh1v+TZ5zG4QorNPm9/FgA7227 intact-crc:BA359D7E5AE04FBD|rigid:x8ujv6G5KzGfNLeJgOtgQrj/A+A false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24080 uniprotkb:P04412 intact:EBI-869415 intact:EBI-197863|uniprotkb:O18370|uniprotkb:O61601|uniprotkb:P81868|uniprotkb:Q9W2G0|ensemblmetazoa:FBpp0071571 psi-mi:q24080_drome(display_long)|uniprotkb:Shc(gene name)|psi-mi:Shc(display_short)|uniprotkb:shc(gene name synonym)|uniprotkb:CG3715(orf name) psi-mi:egfr_drome(display_long)|uniprotkb:Egfr(gene name)|psi-mi:Egfr(display_short)|uniprotkb:top(gene name synonym)|uniprotkb:DER(gene name synonym)|uniprotkb:c-erbB(gene name synonym)|uniprotkb:CG10079(orf name)|uniprotkb:Gurken receptor(gene name synonym)|uniprotkb:Protein torpedo(gene name synonym)|uniprotkb:Drosophila relative of ERBB(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872742 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0015296|go:"GO:0005886"(plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000980(SH2 motif)|interpro:IPR006019("Phosphotyrosine interaction (PID or PI)")|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035676|interpro:IPR036860 refseq:NP_476759.1|flybase:FBgn0003731|dip:DIP-17316N|ensemblmetazoa:FBgn0003731(gene)|ensemblmetazoa:FBtr0071654(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003015"(heart process)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007431"(salivary gland development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007477"(notum development)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007482"(haltere development)|go:"GO:0008071"(maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008355"(olfactory learning)|go:"GO:0008406"(gonad development)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0022008"(neurogenesis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035310"(notum cell fate specification)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|mint:P04412|rcsb pdb:3I2T|rcsb pdb:3LTF|rcsb pdb:3LTG|reactome:R-DME-1227986|reactome:R-DME-1250196|reactome:R-DME-1251985|reactome:R-DME-1253288|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-177929|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-1963642|reactome:R-DME-212718|reactome:R-DME-2179392|reactome:R-DME-416572|reactome:R-DME-5673001|reactome:R-DME-6785631|reactome:R-DME-6811558|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-9018519|reactome:R-DME-9652282 pubmed:10882065(see-also)|pubmed:7651398(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:2kguXmpfINpqc8t7N5is718hP0U7227 rogid:Ae9kedh1v+TZ5zG4QorNPm9/FgA7227 intact-crc:5E339580AA500F76|rigid:IyEEjuVZW5fyaR6DK6Ornra5WpQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VVJ6 uniprotkb:P04412 intact:EBI-174483|ensemblmetazoa:FBpp0074961 intact:EBI-197863|uniprotkb:O18370|uniprotkb:O61601|uniprotkb:P81868|uniprotkb:Q9W2G0|ensemblmetazoa:FBpp0071571 psi-mi:q9vvj6_drome(display_long)|uniprotkb:Krn(gene name)|psi-mi:Krn(display_short)|uniprotkb:Keren(gene name synonym)|uniprotkb:CT19073(gene name synonym)|uniprotkb:Dmel\CG32179(gene name synonym)|uniprotkb:Ker(gene name synonym)|uniprotkb:gritz(gene name synonym)|uniprotkb:keren(gene name synonym)|uniprotkb:krn(gene name synonym)|uniprotkb:s-krn(gene name synonym)|uniprotkb:skrn(gene name synonym)|uniprotkb:spitz2(gene name synonym)|uniprotkb:Dmel_CG32179(orf name)|uniprotkb:CG8056(gene name synonym)|uniprotkb:CG32179(orf name)|uniprotkb:KRN(gene name synonym) psi-mi:egfr_drome(display_long)|uniprotkb:Egfr(gene name)|psi-mi:Egfr(display_short)|uniprotkb:top(gene name synonym)|uniprotkb:DER(gene name synonym)|uniprotkb:c-erbB(gene name synonym)|uniprotkb:CG10079(orf name)|uniprotkb:Gurken receptor(gene name synonym)|uniprotkb:Protein torpedo(gene name synonym)|uniprotkb:Drosophila relative of ERBB(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872746 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524129.1|flybase:FBgn0052179|go:"GO:0016021"(integral component of membrane)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048749"(compound eye development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|ensemblmetazoa:FBgn0052179(gene)|ensemblmetazoa:FBtr0075197(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning) refseq:NP_476759.1|flybase:FBgn0003731|dip:DIP-17316N|ensemblmetazoa:FBgn0003731(gene)|ensemblmetazoa:FBtr0071654(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003015"(heart process)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007431"(salivary gland development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007477"(notum development)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007482"(haltere development)|go:"GO:0008071"(maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008355"(olfactory learning)|go:"GO:0008406"(gonad development)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0022008"(neurogenesis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035310"(notum cell fate specification)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|mint:P04412|rcsb pdb:3I2T|rcsb pdb:3LTF|rcsb pdb:3LTG|reactome:R-DME-1227986|reactome:R-DME-1250196|reactome:R-DME-1251985|reactome:R-DME-1253288|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-177929|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-1963642|reactome:R-DME-212718|reactome:R-DME-2179392|reactome:R-DME-416572|reactome:R-DME-5673001|reactome:R-DME-6785631|reactome:R-DME-6811558|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-9018519|reactome:R-DME-9652282 pubmed:12169631(see-also)|pubmed:12169630(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:F2CAuU2khjCjOygFAuFiVYiNcbk7227 rogid:Ae9kedh1v+TZ5zG4QorNPm9/FgA7227 intact-crc:589BAE7F7894802E|rigid:yJMyqAbcpMRxpiqThuGv9VpaLko false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42287 uniprotkb:P04412 intact:EBI-122571|uniprotkb:Q9VLL2|ensemblmetazoa:FBpp0079313 intact:EBI-197863|uniprotkb:O18370|uniprotkb:O61601|uniprotkb:P81868|uniprotkb:Q9W2G0|ensemblmetazoa:FBpp0071571 psi-mi:grk_drome(display_long)|uniprotkb:CG17610(orf name)|uniprotkb:grk(gene name)|psi-mi:grk(display_short) psi-mi:egfr_drome(display_long)|uniprotkb:Egfr(gene name)|psi-mi:Egfr(display_short)|uniprotkb:top(gene name synonym)|uniprotkb:DER(gene name synonym)|uniprotkb:c-erbB(gene name synonym)|uniprotkb:CG10079(orf name)|uniprotkb:Gurken receptor(gene name synonym)|uniprotkb:Protein torpedo(gene name synonym)|uniprotkb:Drosophila relative of ERBB(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872750 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-20922N|refseq:NP_476568.2|flybase:FBgn0001137|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008070"(maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:5F5K|rcsb pdb:6PJP|rcsb pdb:6PJQ|rcsb pdb:6PJR|rcsb pdb:6PJU|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|ensemblmetazoa:FBgn0001137(gene)|ensemblmetazoa:FBtr0079708(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space) refseq:NP_476759.1|flybase:FBgn0003731|dip:DIP-17316N|ensemblmetazoa:FBgn0003731(gene)|ensemblmetazoa:FBtr0071654(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003015"(heart process)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007431"(salivary gland development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007477"(notum development)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007482"(haltere development)|go:"GO:0008071"(maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008355"(olfactory learning)|go:"GO:0008406"(gonad development)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0022008"(neurogenesis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035149"(lumen formation, open tracheal system)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035310"(notum cell fate specification)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|mint:P04412|rcsb pdb:3I2T|rcsb pdb:3LTF|rcsb pdb:3LTG|reactome:R-DME-1227986|reactome:R-DME-1250196|reactome:R-DME-1251985|reactome:R-DME-1253288|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-177929|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-1963642|reactome:R-DME-212718|reactome:R-DME-2179392|reactome:R-DME-416572|reactome:R-DME-5673001|reactome:R-DME-6785631|reactome:R-DME-6811558|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-8863795|reactome:R-DME-9018519|reactome:R-DME-9652282 pubmed:11782411(see-also)|pubmed:7691414(see-also)|pubmed:11866425(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:9TGh46UunwejPDdD4Zxav6Xbl2M7227 rogid:Ae9kedh1v+TZ5zG4QorNPm9/FgA7227 intact-crc:A283EBC1412769DF|rigid:ULOA1Q61Jd4IJHB0EEtQzSMvHas false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9XZ56 uniprotkb:P48598 intact:EBI-112695|ensemblmetazoa:FBpp0077213|ensemblmetazoa:FBpp0311456 intact:EBI-198574|uniprotkb:Q95SV3|uniprotkb:Q9VSX8|uniprotkb:Q9VSX9|uniprotkb:A4V1Q6|ensemblmetazoa:FBpp0076215|ensemblmetazoa:FBpp0076217|ensemblmetazoa:FBpp0076218|ensemblmetazoa:FBpp0076219|ensemblmetazoa:FBpp0076220|ensemblmetazoa:FBpp0076221|ensemblmetazoa:FBpp0306016|ensemblmetazoa:FBpp0306017 psi-mi:4ebp_drome(display_long)|uniprotkb:Thor(gene name)|psi-mi:Thor(display_short)|uniprotkb:4E-binding protein Thor(gene name synonym)|uniprotkb:CG8846(orf name) psi-mi:if4e_drome(display_long)|uniprotkb:eIF4E1(gene name)|psi-mi:eIF4E1(display_short)|uniprotkb:Eif4e(gene name synonym)|uniprotkb:eIF-4E(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:CG4035(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872754 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477295.1|flybase:FBgn0261560|refseq:NP_001285588.1|ensemblmetazoa:FBgn0261560(gene)|ensemblmetazoa:FBtr0077524(transcript)|ensemblmetazoa:FBtr0345289(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009617"(response to bacterium)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042594"(response to starvation)|go:"GO:0045087"(innate immune response)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1905536"(negative regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|rcsb pdb:4UE8|reactome:R-DME-110523|reactome:R-DME-166208|reactome:R-DME-72662 refseq:NP_001261626.1|refseq:NP_001261627.1|refseq:NP_524829.1|refseq:NP_729480.1|refseq:NP_729481.1|refseq:NP_729482.1|refseq:NP_729483.1|refseq:NP_729484.1|refseq:NP_729485.1|flybase:FBgn0015218|dip:DIP-17448N|ensemblmetazoa:FBgn0015218(gene)|ensemblmetazoa:FBtr0076487(transcript)|ensemblmetazoa:FBtr0076489(transcript)|ensemblmetazoa:FBtr0076490(transcript)|ensemblmetazoa:FBtr0076491(transcript)|ensemblmetazoa:FBtr0076492(transcript)|ensemblmetazoa:FBtr0076493(transcript)|ensemblmetazoa:FBtr0333884(transcript)|ensemblmetazoa:FBtr0333885(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045182"(translation regulator activity)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098794"(postsynapse)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|rcsb pdb:4AXG|rcsb pdb:4UE8|rcsb pdb:4UE9|rcsb pdb:4UEA|rcsb pdb:4UEB|rcsb pdb:4UEC|rcsb pdb:5ABU|rcsb pdb:5ABV|rcsb pdb:5T47|rcsb pdb:5T48|reactome:R-DME-110523|reactome:R-DME-1169408|reactome:R-DME-156827|reactome:R-DME-159227|reactome:R-DME-159230|reactome:R-DME-159231|reactome:R-DME-166208|reactome:R-DME-429947|reactome:R-DME-72649|reactome:R-DME-72662|reactome:R-DME-72702 pubmed:10811906(see-also)|pubmed:11389445(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:BSs5we6e7D1aDFfyiDA0uCtui0Q7227 rogid:htX4CrNeZ/TE59IjlVxQ9GeQdxk7227 intact-crc:C71BE2E0E9AB2EC5|rigid:ajh6EMnhGa7tp8WMR5cPfZoFho0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09052 uniprotkb:Q9NJH7 intact:EBI-134067|uniprotkb:Q24582|uniprotkb:Q8SXU8|uniprotkb:Q9V3Q8|ensemblmetazoa:FBpp0401445|ensemblmetazoa:FBpp0401446|ensemblmetazoa:FBpp0401447 intact:EBI-869429|ensemblmetazoa:FBpp0301573 psi-mi:vasa1_drome(display_long)|uniprotkb:vas(gene name)|psi-mi:vas(display_short)|uniprotkb:Antigen Mab46F11(gene name synonym)|uniprotkb:vasa(gene name synonym)|uniprotkb:CG46283(orf name) psi-mi:q9njh7_drome(display_long)|uniprotkb:eIF5B(gene name)|psi-mi:eIF5B(display_short)|uniprotkb:cIF2(gene name synonym)|uniprotkb:CG10840(orf name)|uniprotkb:Translation initiation factor IF-2(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872762 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283442|refseq:NP_723899.1|refseq:NP_001303322.1|refseq:NP_001260458.1|ensemblmetazoa:FBgn0283442(gene)|rcsb pdb:2IHS|rcsb pdb:3EMW|rcsb pdb:3F2O|rcsb pdb:5NT7|ensemblmetazoa:FBtr0445185(transcript)|ensemblmetazoa:FBtr0445186(transcript)|ensemblmetazoa:FBtr0445187(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0008104"(protein localization)|go:"GO:0030154"(cell differentiation)|go:"GO:0043073"(germ cell nucleus)|go:"GO:0043186"(P granule)|go:"GO:0048477"(oogenesis)|go:"GO:0061803"(posterior cell cortex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|mint:P09052|rcsb pdb:2DB3|dip:DIP-20604N flybase:FBgn0026259|ensemblmetazoa:FBgn0026259(gene)|ensemblmetazoa:FBtr0309839(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR023115|interpro:IPR027417|interpro:IPR036925 pubmed:11262236(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:MPzIr/Dex98V189t6FOs8l0nQnM7227 rogid:gYnZe6RE0B+oDQ9SfsDOK/pa/OE7227 intact-crc:0BB423433FA95407|rigid:W/Cp5MyX+kDemIr1kC2AjaRqJnk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10084 uniprotkb:P18491 intact:EBI-174136|intact:EBI-1639078|uniprotkb:O76890|uniprotkb:Q4V705|ensemblmetazoa:FBpp0070072 intact:EBI-105737|intact:EBI-1639647|uniprotkb:Q9W0N0|intact:EBI-3431186|ensemblmetazoa:FBpp0072477 psi-mi:ast4_drome(display_long)|uniprotkb:sc(gene name)|psi-mi:sc(display_short)|uniprotkb:T4(gene name synonym)|uniprotkb:Protein scute(gene name synonym)|uniprotkb:sis-b(gene name synonym)|uniprotkb:CG3827(orf name) psi-mi:emc_drome(display_long)|uniprotkb:emc(gene name)|psi-mi:emc(display_short)|uniprotkb:CG1007(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872766 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476803.1|flybase:FBgn0004170|dip:DIP-325N|ensemblmetazoa:FBgn0004170(gene)|ensemblmetazoa:FBtr0070073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638 interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|go:"GO:0046552"(photoreceptor cell fate commitment)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0061525"(hindgut development)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_523876.2|flybase:FBgn0000575|dip:DIP-73N|ensemblmetazoa:FBgn0000575(gene)|ensemblmetazoa:FBtr0072578(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007391"(dorsal closure)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0007530"(sex determination)|go:"GO:0008258"(head involution)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0030154"(cell differentiation) pubmed:7821225(see-also)|pubmed:8497266(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:WTTmp3SuZ10YiZMKYALr68UiRO07227 rogid:JfE7tW1Lu4C7KafkWe31A98gZoM7227 intact-crc:F91E9F66400D0068|rigid:vlm7j3+GkJO8P6lezqqdH14O9YI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09774 uniprotkb:P18491 intact:EBI-174224|intact:EBI-1628024|uniprotkb:Q24387|uniprotkb:Q8MRA5|ensemblmetazoa:FBpp0070073 intact:EBI-105737|intact:EBI-1639647|uniprotkb:Q9W0N0|intact:EBI-3431186|ensemblmetazoa:FBpp0072477 psi-mi:ast3_drome(display_long)|uniprotkb:"l(1)sc"(gene name)|psi-mi:"l(1)sc"(display_short)|uniprotkb:T3(gene name synonym)|uniprotkb:l'sc(gene name synonym)|uniprotkb:CG3839(orf name)|uniprotkb:Protein lethal of scute(gene name synonym) psi-mi:emc_drome(display_long)|uniprotkb:emc(gene name)|psi-mi:emc(display_short)|uniprotkb:CG1007(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872770 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476623.1|flybase:FBgn0002561|ensemblmetazoa:FBgn0002561(gene)|ensemblmetazoa:FBtr0070074(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638 interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|go:"GO:0046552"(photoreceptor cell fate commitment)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0061525"(hindgut development)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_523876.2|flybase:FBgn0000575|dip:DIP-73N|ensemblmetazoa:FBgn0000575(gene)|ensemblmetazoa:FBtr0072578(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007391"(dorsal closure)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0007530"(sex determination)|go:"GO:0008258"(head involution)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0030154"(cell differentiation) pubmed:7821225(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6/qKHfmqMOsi8uWoKA4A3IbeOGk7227 rogid:JfE7tW1Lu4C7KafkWe31A98gZoM7227 intact-crc:53EB6F1AF61EF7C4|rigid:diQvB0fdVCUAMAg/CPZck0QqPgw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O46339 uniprotkb:P02836 intact:EBI-137488|intact:EBI-497943|intact:EBI-1558099|uniprotkb:Q8INL6|uniprotkb:O17427|uniprotkb:Q058V1|uniprotkb:Q4AB34|uniprotkb:Q59DX7|uniprotkb:Q6NR42|uniprotkb:Q7KQ21|uniprotkb:Q9VGY9|uniprotkb:Q8INL5|intact:EBI-3431899|ensemblmetazoa:FBpp0081732 intact:EBI-121995|uniprotkb:P02837|uniprotkb:Q0E9C0|uniprotkb:Q24356|uniprotkb:Q9V601|ensemblmetazoa:FBpp0087197|ensemblmetazoa:FBpp0087198 psi-mi:hth_drome(display_long)|uniprotkb:hth(gene name)|psi-mi:hth(display_short)|uniprotkb:dtl(gene name synonym)|uniprotkb:Homeobox protein dorsotonals(gene name synonym)|uniprotkb:CG17117(orf name) psi-mi:hmen_drome(display_long)|uniprotkb:en(gene name)|psi-mi:en(display_short)|uniprotkb:CG9015(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872774 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476577.3|refseq:NP_001014613.2|refseq:NP_001027170.1|refseq:NP_476576.1|refseq:NP_476578.3|flybase:FBgn0001235|ensemblmetazoa:FBgn0001235(gene)|ensemblmetazoa:FBtr0082255(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0001752"(compound eye photoreceptor fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007380"(specification of segmental identity, head)|go:"GO:0007383"(specification of segmental identity, antennal segment)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035282"(segmentation)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0048735"(haltere morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0072002"(Malpighian tubule development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000497"(positive regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|reactome:R-DME-390193 ensemblmetazoa:FBgn0000577(gene)|ensemblmetazoa:FBtr0088095(transcript)|ensemblmetazoa:FBtr0088096(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007388"(posterior compartment specification)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007418"(ventral midline development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007487"(analia development)|go:"GO:0008406"(gonad development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035215"(genital disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035288"(anterior head segmentation)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048099"(anterior/posterior lineage restriction, imaginal disc)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR000747('Homeobox' engrailed-type protein)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR019549|interpro:IPR019737|interpro:IPR020479|rcsb pdb:1DU0|rcsb pdb:1ENH|rcsb pdb:1HDD|rcsb pdb:1P7I|rcsb pdb:1P7J|rcsb pdb:1ZTR|rcsb pdb:2HDD|rcsb pdb:2HOS|rcsb pdb:2HOT|rcsb pdb:2JWT|rcsb pdb:2P81|rcsb pdb:3HDD|rcsb pdb:6FVC|rcsb pdb:6M3D|refseq:NP_523700.2|refseq:NP_725059.1|flybase:FBgn0000577 pubmed:12506004(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:3+HaeG85WPZHxn++kVkx3QXQvXU7227 rogid:3uusonfCVviXiwx/s34raqI1DfM7227 intact-crc:4B2B96EF3AF5CB11|rigid:Z+id5EseWE8304wDFYTADUXjJ+U false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16371 uniprotkb:P02836 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 intact:EBI-121995|uniprotkb:P02837|uniprotkb:Q0E9C0|uniprotkb:Q24356|uniprotkb:Q9V601|ensemblmetazoa:FBpp0087197|ensemblmetazoa:FBpp0087198 psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:hmen_drome(display_long)|uniprotkb:en(gene name)|psi-mi:en(display_short)|uniprotkb:CG9015(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872778 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N ensemblmetazoa:FBgn0000577(gene)|ensemblmetazoa:FBtr0088095(transcript)|ensemblmetazoa:FBtr0088096(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007388"(posterior compartment specification)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007418"(ventral midline development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007487"(analia development)|go:"GO:0008406"(gonad development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035215"(genital disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035288"(anterior head segmentation)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048099"(anterior/posterior lineage restriction, imaginal disc)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR000747('Homeobox' engrailed-type protein)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR019549|interpro:IPR019737|interpro:IPR020479|rcsb pdb:1DU0|rcsb pdb:1ENH|rcsb pdb:1HDD|rcsb pdb:1P7I|rcsb pdb:1P7J|rcsb pdb:1ZTR|rcsb pdb:2HDD|rcsb pdb:2HOS|rcsb pdb:2HOT|rcsb pdb:2JWT|rcsb pdb:2P81|rcsb pdb:3HDD|rcsb pdb:6FVC|rcsb pdb:6M3D|refseq:NP_523700.2|refseq:NP_725059.1|flybase:FBgn0000577 pubmed:9367988(see-also)|pubmed:9566899(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 rogid:3uusonfCVviXiwx/s34raqI1DfM7227 intact-crc:EF94734C51A61231|rigid:zwuoBFyyidwcXbG390W/sjPHJ74 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40427 uniprotkb:P02836 intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515 intact:EBI-121995|uniprotkb:P02837|uniprotkb:Q0E9C0|uniprotkb:Q24356|uniprotkb:Q9V601|ensemblmetazoa:FBpp0087197|ensemblmetazoa:FBpp0087198 psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name) psi-mi:hmen_drome(display_long)|uniprotkb:en(gene name)|psi-mi:en(display_short)|uniprotkb:CG9015(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872782 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N ensemblmetazoa:FBgn0000577(gene)|ensemblmetazoa:FBtr0088095(transcript)|ensemblmetazoa:FBtr0088096(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007388"(posterior compartment specification)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007418"(ventral midline development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007487"(analia development)|go:"GO:0008406"(gonad development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035215"(genital disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035288"(anterior head segmentation)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048099"(anterior/posterior lineage restriction, imaginal disc)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR000747('Homeobox' engrailed-type protein)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR019549|interpro:IPR019737|interpro:IPR020479|rcsb pdb:1DU0|rcsb pdb:1ENH|rcsb pdb:1HDD|rcsb pdb:1P7I|rcsb pdb:1P7J|rcsb pdb:1ZTR|rcsb pdb:2HDD|rcsb pdb:2HOS|rcsb pdb:2HOT|rcsb pdb:2JWT|rcsb pdb:2P81|rcsb pdb:3HDD|rcsb pdb:6FVC|rcsb pdb:6M3D|refseq:NP_523700.2|refseq:NP_725059.1|flybase:FBgn0000577 pubmed:12506004(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227 rogid:3uusonfCVviXiwx/s34raqI1DfM7227 intact-crc:3E4510A338A16584|rigid:yt7oJ4VX2WdtLMe4oRZbOxGPkWU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q5U0W6 uniprotkb:Q8T4F7 intact:EBI-869442 intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115 psi-mi:q5u0w6_drome(display_long)|uniprotkb:Zyx(gene name)|psi-mi:Zyx(display_short)|uniprotkb:Zyx102EF(gene name synonym)|uniprotkb:CG32018(orf name) psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872786 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0011642|go:"GO:0001725"(stress fiber)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007593"(chitin-based cuticle sclerotization)|go:"GO:0035002"(liquid clearance, open tracheal system)|go:"GO:0035003"(subapical complex)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0045805"(positive regulation of eclosion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001781(Zinc finger, LIM-type) refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization) pubmed:12594038(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:joGeKKcP0ekbfhEDSEKXAMcQvAs7227 rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227 intact-crc:49DE41684E1D99E7|rigid:XrKgGEGTAegPK4i1cfyCHb9OxQQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O44924 uniprotkb:Q8T4F7 intact:EBI-74797 intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115 psi-mi:o44924_drome(display_long)|uniprotkb:robo1(gene name)|psi-mi:robo1(display_short)|uniprotkb:robo(gene name synonym)|uniprotkb:CG13521(orf name) psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872790 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0005631|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0008038"(neuron recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008406"(gonad development)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0070983"(dendrite guidance)|go:"GO:0071666"(Slit-Robo signaling complex)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2VR9|rcsb pdb:2VRA refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization) pubmed:10892742(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:uLUQxfvRN9BQCyxNV6w22/4BtGw7227 rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227 intact-crc:8EBE6D18AEC7DED3|rigid:fjlzMinQCDvRgJSa82l5JE7TezU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8ST77 uniprotkb:O96435 intact:EBI-869473|ensemblmetazoa:FBpp0088144 intact:EBI-869451 psi-mi:q8st77_drome(display_long)|uniprotkb:CG1862(orf name)|uniprotkb:Ephrin(gene name)|psi-mi:Ephrin(display_short) psi-mi:o96435_drome(display_long)|uniprotkb:Eph(gene name)|psi-mi:Eph(display_short)|uniprotkb:eph(gene name synonym)|uniprotkb:CG1511(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872794 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0040324|ensemblmetazoa:FBgn0040324(gene)|ensemblmetazoa:FBtr0089075(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016319"(mushroom body development)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway) flybase:FBgn0025936|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016319"(mushroom body development)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR036116 pubmed:12183373(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:7+mCiFZOXDuPM+HMlPkze60S5+M7227 rogid:YLw+SeE/7GoDwg9+4IUvj6yRJCw7227 intact-crc:905AF7F6E3318790|rigid:0VRqcCQw+xOvIzA75lzGTfaAEBM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q4U2Q2 uniprotkb:Q95S37 intact:EBI-9630187 intact:EBI-869482 psi-mi:q4u2q2_drome(display_long)|uniprotkb:mus201(gene name)|psi-mi:mus201(display_short)|uniprotkb:CG10890(orf name) psi-mi:q95s37_drome(display_long)|uniprotkb:Ercc1(gene name)|psi-mi:Ercc1(display_short)|uniprotkb:CG10215(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872798 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0002887|go:"GO:0003677"(DNA binding)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR029060|interpro:IPR036279 flybase:FBgn0028434|go:"GO:0000110"(nucleotide-excision repair factor 1 complex)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006296"(nucleotide-excision repair, DNA incision, 5'-to lesion)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR004579(DNA repair protein rad10)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core) pubmed:10812334(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+xGm8bZNo0B2HufJBUhHlDCrUbQ7227 rogid:29azDSNLrdunlVaJLVvYsrWMCZw7227 intact-crc:5EB2CC650F58A57E|rigid:gpphCoCqcchIF7yf9is1a5fDlwU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24087 uniprotkb:Q95S37 intact:EBI-663297|uniprotkb:Q8IHB9|uniprotkb:Q9W4L3|ensemblmetazoa:FBpp0070624|ensemblmetazoa:FBpp0310174 intact:EBI-869482 psi-mi:xpf_drome(display_long)|uniprotkb:Protein meiotic 9(gene name synonym)|uniprotkb:mei-9(gene name)|psi-mi:mei-9(display_short)|uniprotkb:CG3697(orf name) psi-mi:q95s37_drome(display_long)|uniprotkb:Ercc1(gene name)|psi-mi:Ercc1(display_short)|uniprotkb:CG10215(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872802 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525068.1|flybase:FBgn0002707|refseq:NP_001284859.1|ensemblmetazoa:FBgn0002707(gene)|ensemblmetazoa:FBtr0070656(transcript)|ensemblmetazoa:FBtr0343574(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000110"(nucleotide-excision repair factor 1 complex)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006296"(nucleotide-excision repair, DNA incision, 5'-to lesion)|go:"GO:0006298"(mismatch repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0030716"(oocyte fate determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1901255"(nucleotide-excision repair involved in interstrand cross-link repair)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR006167(DNA repair protein)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|reactome:R-DME-5696395|reactome:R-DME-5696400|reactome:R-DME-6782135|go:"GO:0003697"(single-stranded DNA binding) flybase:FBgn0028434|go:"GO:0000110"(nucleotide-excision repair factor 1 complex)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006296"(nucleotide-excision repair, DNA incision, 5'-to lesion)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR004579(DNA repair protein rad10)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core) pubmed:10812334(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:bNXw/9Wdy694IPTd+ddBCdbsvfk7227 rogid:29azDSNLrdunlVaJLVvYsrWMCZw7227 intact-crc:BE49B6106D376EC0|rigid:rJeMK7LZGqaSKMTWW4VWfE7WVHM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P26017 uniprotkb:Q24338 intact:EBI-177152|uniprotkb:Q9VP49|ensemblmetazoa:FBpp0078059 intact:EBI-88911|ensemblmetazoa:FBpp0079907 psi-mi:pc_drome(display_long)|uniprotkb:Pc(gene name)|psi-mi:Pc(display_short)|uniprotkb:CG7618(orf name) psi-mi:esc_drome(display_long)|uniprotkb:esc(gene name)|psi-mi:esc(display_short)|uniprotkb:CG14941(orf name)|uniprotkb:Protein extra sex combs(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872810 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524199.1|flybase:FBgn0003042|ensemblmetazoa:FBgn0003042(gene)|ensemblmetazoa:FBtr0078405(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007385"(specification of segmental identity, abdomen)|go:"GO:0007419"(ventral cord development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0022008"(neurogenesis)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042060"(wound healing)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|rcsb pdb:1PDQ|rcsb pdb:1PFB|reactome:R-DME-3108214|reactome:R-DME-3899300|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724 ensemblmetazoa:FBgn0000588(gene)|ensemblmetazoa:FBtr0080325(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042802"(identical protein binding)|go:"GO:0048096"|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q24338|go:"GO:0016458"(obsolete gene silencing)|refseq:NP_477431.1|flybase:FBgn0000588|dip:DIP-20069N pubmed:11581156(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:EoeY3ywjOXNZO7fubeNPow+WW4w7227 rogid:owOOCkwb0LdPVnElMax3J1OIkEE7227 intact-crc:848345B73C363B4D|rigid:1USUfkBmFRWCSfpNpQRcc5NkAew false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42124 uniprotkb:Q24338 intact:EBI-112315|uniprotkb:Q9VTA3|uniprotkb:B7Z0G2|ensemblmetazoa:FBpp0076008|ensemblmetazoa:FBpp0271846 intact:EBI-88911|ensemblmetazoa:FBpp0079907 psi-mi:ez_drome(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:"E(z)"(gene name)|psi-mi:"E(z)"(display_short)|uniprotkb:CG6502(orf name)|uniprotkb:Protein enhancer of zeste(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym) psi-mi:esc_drome(display_long)|uniprotkb:esc(gene name)|psi-mi:esc(display_short)|uniprotkb:CG14941(orf name)|uniprotkb:Protein extra sex combs(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872814 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524021.2|refseq:NP_001137932.1|flybase:FBgn0000629|dip:DIP-20386N|ensemblmetazoa:FBgn0000629(gene)|ensemblmetazoa:FBtr0076279(transcript)|ensemblmetazoa:FBtr0273338(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016571"(histone methylation)|go:"GO:0022008"(neurogenesis)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:P42124|reactome:R-DME-2559580|reactome:R-DME-8943724 ensemblmetazoa:FBgn0000588(gene)|ensemblmetazoa:FBtr0080325(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042802"(identical protein binding)|go:"GO:0048096"|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q24338|go:"GO:0016458"(obsolete gene silencing)|refseq:NP_477431.1|flybase:FBgn0000588|dip:DIP-20069N pubmed:9566901(see-also)|pubmed:9693151(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:SgDch3Z90h2XcA4b2MqjzZN+gSI7227 rogid:owOOCkwb0LdPVnElMax3J1OIkEE7227 intact-crc:ADB9C276A3FE2A02|rigid:97CWoQ2IMfsQ4bSxZAjIKwtv42U false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20227 uniprotkb:P06602 intact:EBI-169179|uniprotkb:Q9W2D8|ensemblmetazoa:FBpp0071596 intact:EBI-128289|uniprotkb:P07667|uniprotkb:Q9V5E6|ensemblmetazoa:FBpp0087478 psi-mi:tbp_drome(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:CG9874(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:eve_drome(display_long)|uniprotkb:eve(gene name)|psi-mi:eve(display_short)|uniprotkb:CG2328(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872818 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523805.1|flybase:FBgn0003687|ensemblmetazoa:FBgn0003687(gene)|ensemblmetazoa:FBtr0071679(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519|dip:DIP-80N refseq:NP_523670.2|flybase:FBgn0000606|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1JGG|ensemblmetazoa:FBgn0000606(gene)|ensemblmetazoa:FBtr0088390(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007376"(cephalic furrow formation)|go:"GO:0007377"(germ-band extension)|go:"GO:0007512"(adult heart development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009997"(negative regulation of cardioblast cell fate specification)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:0003677"(DNA binding) pubmed:7651419(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:eRlX8luNoF4M7SFmEnxKSbI6FJo7227 rogid:WwyHWF4Qi7SifaofqFkM2cGiDOk7227 intact-crc:4A889C3A3EE317C3|rigid:bf0/UlDeUsO9ew13hclHTTgpsXA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18431 uniprotkb:P06602 intact:EBI-242141|uniprotkb:O76881|uniprotkb:P23646|uniprotkb:Q27603|uniprotkb:Q27604|uniprotkb:Q27605|uniprotkb:Q8MRF7|uniprotkb:Q9NF42|uniprotkb:Q9U094|uniprotkb:Q9W4X3|ensemblmetazoa:FBpp0070449|ensemblmetazoa:FBpp0070451|ensemblmetazoa:FBpp0070452|ensemblmetazoa:FBpp0070453|ensemblmetazoa:FBpp0089158|ensemblmetazoa:FBpp0089162 intact:EBI-128289|uniprotkb:P07667|uniprotkb:Q9V5E6|ensemblmetazoa:FBpp0087478 psi-mi:sgg_drome(display_long)|uniprotkb:sgg(gene name)|psi-mi:sgg(display_short)|uniprotkb:zw3(gene name synonym)|uniprotkb:CG2621(orf name)|uniprotkb:Protein zeste-white 3(gene name synonym)|uniprotkb:gsk3(gene name synonym) psi-mi:eve_drome(display_long)|uniprotkb:eve(gene name)|psi-mi:eve(display_short)|uniprotkb:CG2328(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872822 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476714.1|refseq:NP_476715.1|refseq:NP_476716.2|refseq:NP_599105.1|refseq:NP_726822.1|refseq:NP_726823.1|refseq:NP_996335.1|refseq:NP_996336.1|refseq:NP_996337.1|refseq:NP_996338.1|flybase:FBgn0003371|dip:DIP-39170N|ensemblmetazoa:FBgn0003371(gene)|ensemblmetazoa:FBtr0070466(transcript)|ensemblmetazoa:FBtr0070468(transcript)|ensemblmetazoa:FBtr0070469(transcript)|ensemblmetazoa:FBtr0070470(transcript)|ensemblmetazoa:FBtr0070472(transcript)|ensemblmetazoa:FBtr0070473(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007165"(signal transduction)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007507"(heart development)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008355"(olfactory learning)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0022416"(chaeta development)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030424"(axon)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035324"(female germline ring canal)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045169"(fusome)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046959"(habituation)|go:"GO:0048477"(oogenesis)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070884"(regulation of calcineurin-NFAT signaling cascade)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209387|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3371453|reactome:R-DME-399956|reactome:R-DME-432553|reactome:R-DME-4641262|reactome:R-DME-5610785 refseq:NP_523670.2|flybase:FBgn0000606|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1JGG|ensemblmetazoa:FBgn0000606(gene)|ensemblmetazoa:FBtr0088390(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007376"(cephalic furrow formation)|go:"GO:0007377"(germ-band extension)|go:"GO:0007512"(adult heart development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009997"(negative regulation of cardioblast cell fate specification)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:0003677"(DNA binding) pubmed:10024881(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:sUjAtUAobW55mTZBsRiQg0K1U9o7227 rogid:WwyHWF4Qi7SifaofqFkM2cGiDOk7227 intact-crc:5247B38321EFBC86|rigid:F2QE/VHiMn1BtrvSsvh/ed2AYGI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KUA8 uniprotkb:P06602 intact:EBI-869512|ensemblmetazoa:FBpp0089427|ensemblmetazoa:FBpp0296976 intact:EBI-128289|uniprotkb:P07667|uniprotkb:Q9V5E6|ensemblmetazoa:FBpp0087478 psi-mi:q7kua8_drome(display_long)|uniprotkb:Gug(gene name)|psi-mi:Gug(display_short)|uniprotkb:Atro(gene name synonym)|uniprotkb:Dmel\CG6964(gene name synonym)|uniprotkb:GUG(gene name synonym)|uniprotkb:atro(gene name synonym)|uniprotkb:gug(gene name synonym)|uniprotkb:"l(3)01323"(gene name synonym)|uniprotkb:"l(3)03928"(gene name synonym)|uniprotkb:"l(3)S146907"(gene name synonym)|uniprotkb:"l(3)j5A3"(gene name synonym)|uniprotkb:"l(3)rO116"(gene name synonym)|uniprotkb:Dmel_CG6964(orf name)|uniprotkb:CG6964(orf name) psi-mi:eve_drome(display_long)|uniprotkb:eve(gene name)|psi-mi:eve(display_short)|uniprotkb:CG2328(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872826 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_996025.1|flybase:FBgn0010825|refseq:NP_001246670.1|ensemblmetazoa:FBgn0010825(gene)|ensemblmetazoa:FBtr0076619(transcript)|ensemblmetazoa:FBtr0305696(transcript)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0007379"(segment specification)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035282"(segmentation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR002951(Atrophin)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884 refseq:NP_523670.2|flybase:FBgn0000606|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1JGG|ensemblmetazoa:FBgn0000606(gene)|ensemblmetazoa:FBtr0088390(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007376"(cephalic furrow formation)|go:"GO:0007377"(germ-band extension)|go:"GO:0007512"(adult heart development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009997"(negative regulation of cardioblast cell fate specification)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:0003677"(DNA binding) pubmed:11792320(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:71LMTkSbQbK24u/4jXWxpMmO5P47227 rogid:WwyHWF4Qi7SifaofqFkM2cGiDOk7227 intact-crc:413F72A04869216E|rigid:p8R9kUVWwEKhTF2yRgbKU+8LbGA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16371 uniprotkb:P06602 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 intact:EBI-128289|uniprotkb:P07667|uniprotkb:Q9V5E6|ensemblmetazoa:FBpp0087478 psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:eve_drome(display_long)|uniprotkb:eve(gene name)|psi-mi:eve(display_short)|uniprotkb:CG2328(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872830 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N refseq:NP_523670.2|flybase:FBgn0000606|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1JGG|ensemblmetazoa:FBgn0000606(gene)|ensemblmetazoa:FBtr0088390(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007376"(cephalic furrow formation)|go:"GO:0007377"(germ-band extension)|go:"GO:0007512"(adult heart development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009997"(negative regulation of cardioblast cell fate specification)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:0003677"(DNA binding) pubmed:11311161(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 rogid:WwyHWF4Qi7SifaofqFkM2cGiDOk7227 intact-crc:3AC67E4CCF823B52|rigid:loa/IO1zeUlEo5tt2IpnTXP99Ys false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24564 uniprotkb:Q07436 intact:EBI-180142|uniprotkb:Q24054|uniprotkb:Q8SWY3|ensemblmetazoa:FBpp0074523|ensemblmetazoa:FBpp0311877 intact:EBI-192660|uniprotkb:Q9VPQ0|ensemblmetazoa:FBpp0077719|ensemblmetazoa:FBpp0302878 psi-mi:merh_drome(display_long)|uniprotkb:Mer(gene name)|psi-mi:Mer(display_short)|uniprotkb:EMR2(gene name synonym)|uniprotkb:CG14228(orf name)|uniprotkb:Ezrin-moesin-radixin 2(gene name synonym)|uniprotkb:Merlin(gene name synonym) psi-mi:expa_drome(display_long)|uniprotkb:ex(gene name)|psi-mi:ex(display_short)|uniprotkb:CG4114(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872834 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523413.1|flybase:FBgn0086384|refseq:NP_001285458.1|dip:DIP-17087N|ensemblmetazoa:FBgn0086384(gene)|ensemblmetazoa:FBtr0074754(transcript)|ensemblmetazoa:FBtr0345992(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009798"(axis specification)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016006"(Nebenkern)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035329"(hippo signaling)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0036375"(Kibra-Ex-Mer complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046669"(regulation of compound eye retinal cell programmed cell death)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0120219"(subapical part of cell)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|rcsb pdb:7EDR|reactome:R-DME-2029482|reactome:R-DME-5627123 refseq:NP_476840.2|flybase:FBgn0004583|refseq:NP_001259823.1|dip:DIP-59337N|ensemblmetazoa:FBgn0004583(gene)|ensemblmetazoa:FBtr0078059(transcript)|ensemblmetazoa:FBtr0329832(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0036375"(Kibra-Ex-Mer complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:0120219"(subapical part of cell)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041781|reactome:R-DME-451806 pubmed:10683183(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:L3AloQnHvXayDqSyF+QhKptEjjQ7227 rogid:jCsq6JzSOCfaz06zd5R8hdkiWVg7227 intact-crc:C214D7F18A4B5115|rigid:C430WYMuKQRPyVO+YWgfdmQSg+c false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P83949 uniprotkb:P40427 intact:EBI-202590|uniprotkb:P02834|uniprotkb:Q9TX83|uniprotkb:Q9VER4|uniprotkb:Q9VER5|ensemblmetazoa:FBpp0082793 intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515 psi-mi:ubx_drome(display_long)|uniprotkb:Ubx(gene name)|psi-mi:Ubx(display_short)|uniprotkb:CG10388(orf name) psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872838 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_536748.1|refseq:NP_536752.1|refseq:NP_732171.1|refseq:NP_732172.1|refseq:NP_732173.1|refseq:NP_996219.1|flybase:FBgn0003944|dip:DIP-33048N|ensemblmetazoa:FBgn0003944(gene)|ensemblmetazoa:FBtr0083347(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001706"(endoderm formation)|go:"GO:0001709"(cell fate determination)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007384"(specification of segmental identity, thorax)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007494"(midgut development)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0007507"(heart development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035052"(dorsal vessel aortic cell fate commitment)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048636"(positive regulation of muscle organ development)|go:"GO:0060969"(obsolete negative regulation of gene silencing)|go:"GO:0061327"(anterior Malpighian tubule development)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1B8I|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:4UUT refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N pubmed:7846045(see-also)|pubmed:7915199(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:PciTV5UxWTqbliI2WZAasPEr42g7227 rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227 intact-crc:E23207C31A02561D|rigid:M+fmYYjItm5I/cFREJYtr3DsNrM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09077 uniprotkb:P40427 intact:EBI-666569|uniprotkb:Q23990|uniprotkb:Q24508|uniprotkb:Q9V3Q3|ensemblmetazoa:FBpp0081163|ensemblmetazoa:FBpp0089393 intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515 psi-mi:scr_drome(display_long)|uniprotkb:Scr(gene name)|psi-mi:Scr(display_short)|uniprotkb:CG1030(orf name) psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872842 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524248.2|refseq:NP_996165.1|flybase:FBgn0003339|dip:DIP-40017N|ensemblmetazoa:FBgn0003339(gene)|ensemblmetazoa:FBtr0081657(transcript)|ensemblmetazoa:FBtr0081658(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007494"(midgut development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045498"(sex comb development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|rcsb pdb:2R5Y|rcsb pdb:2R5Z refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N pubmed:10398683(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:z5Lj6W1yKerSXCkC3CX96vECd507227 rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227 intact-crc:EE478F1D81591C86|rigid:p3Jky7oQNHF4HFdb/wzWdZTVKyk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O46339 uniprotkb:P40427 intact:EBI-137488|intact:EBI-497943|intact:EBI-1558099|uniprotkb:Q8INL6|uniprotkb:O17427|uniprotkb:Q058V1|uniprotkb:Q4AB34|uniprotkb:Q59DX7|uniprotkb:Q6NR42|uniprotkb:Q7KQ21|uniprotkb:Q9VGY9|uniprotkb:Q8INL5|intact:EBI-3431899|ensemblmetazoa:FBpp0081732 intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515 psi-mi:hth_drome(display_long)|uniprotkb:hth(gene name)|psi-mi:hth(display_short)|uniprotkb:dtl(gene name synonym)|uniprotkb:Homeobox protein dorsotonals(gene name synonym)|uniprotkb:CG17117(orf name) psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872846 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476577.3|refseq:NP_001014613.2|refseq:NP_001027170.1|refseq:NP_476576.1|refseq:NP_476578.3|flybase:FBgn0001235|ensemblmetazoa:FBgn0001235(gene)|ensemblmetazoa:FBtr0082255(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0001752"(compound eye photoreceptor fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007380"(specification of segmental identity, head)|go:"GO:0007383"(specification of segmental identity, antennal segment)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035282"(segmentation)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0048735"(haltere morphogenesis)|go:"GO:0048749"(compound eye development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0072002"(Malpighian tubule development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000497"(positive regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|reactome:R-DME-390193 refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N pubmed:9450936(see-also)|pubmed:9463350(see-also)|pubmed:10529430(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:3+HaeG85WPZHxn++kVkx3QXQvXU7227 rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227 intact-crc:D9C90CFE13DBCCC5|rigid:s8bemnV/cDUFpN8KE0D+icTyLVw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P31264 uniprotkb:O18381 intact:EBI-869531|uniprotkb:O97058|uniprotkb:Q9VI44|uniprotkb:Q4JFI5|ensemblmetazoa:FBpp0088333 intact:EBI-232318|uniprotkb:Q8ST91|uniprotkb:Q8ST92|uniprotkb:Q9V4F5 psi-mi:hmpb_drome(display_long)|uniprotkb:pb(gene name)|psi-mi:pb(display_short)|uniprotkb:CG31481(orf name) psi-mi:pax6_drome(display_long)|uniprotkb:ey(gene name)|psi-mi:ey(display_short)|uniprotkb:pax6(gene name synonym)|uniprotkb:CG1464(orf name)|uniprotkb:Protein eyeless(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872850 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476669.3|refseq:NP_996161.1|refseq:NP_996162.1|refseq:NP_996163.1|flybase:FBgn0051481|ensemblmetazoa:FBgn0051481(gene)|ensemblmetazoa:FBtr0089276(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007381"(specification of segmental identity, labial segment)|go:"GO:0007382"(specification of segmental identity, maxillary segment)|go:"GO:0048728"(proboscis development)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479 refseq:NP_524628.2|refseq:NP_726607.1|flybase:FBgn0005558|dip:DIP-46285N|go:"GO:0043704"(photoreceptor cell fate specification)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048036"(central complex development)|go:"GO:0048749"(compound eye development)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048856"(anatomical structure development)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|reactome:R-DME-8939245|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0016319"(mushroom body development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway) pubmed:12490563(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:kv0/YsaNKPyeKuzmiDPE33GRS/Q7227 rogid:5c/N+xgYitvP49d/QbUAWYs7J+A7227 intact-crc:A8FF2235E94DF69C|rigid:/Fusbp8rAeWEBpRzUZPNRMJvSco false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q27350 uniprotkb:Q05201 intact:EBI-161504|intact:EBI-1631381|uniprotkb:A0AVT8|uniprotkb:Q9V4L0|ensemblmetazoa:FBpp0089177 intact:EBI-209758|uniprotkb:Q961V4|uniprotkb:Q9VMC1|ensemblmetazoa:FBpp0078964 psi-mi:so_drome(display_long)|uniprotkb:so(gene name)|psi-mi:so(display_short)|uniprotkb:CG11121(orf name) psi-mi:eya_drome(display_long)|uniprotkb:eya(gene name)|psi-mi:eya(display_short)|uniprotkb:cli(gene name synonym)|uniprotkb:CG9554(orf name)|uniprotkb:Protein Clift(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872854 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476733.1|flybase:FBgn0003460|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008347"(glial cell migration)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0035271"(ring gland development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|ensemblmetazoa:FBgn0003460(gene)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR031701|ensemblmetazoa:FBtr0088970(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001744"(insect visual primordium formation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001746"(Bolwig's organ morphogenesis)|dip:DIP-18228N refseq:NP_523492.1|refseq:NP_723188.1|flybase:FBgn0000320|dip:DIP-19253N|ensemblmetazoa:FBgn0000320(gene)|ensemblmetazoa:FBtr0079335(transcript)|go:"GO:0001744"(insect visual primordium formation)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007419"(ventral cord development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008406"(gonad development)|go:"GO:0008584"(male gonad development)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030946"(protein tyrosine phosphatase activity, metal-dependent)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0070285"(pigment cell development)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR006545(EYA)|interpro:IPR028472|interpro:IPR038102|interpro:IPR042577 pubmed:9428512(see-also)|pubmed:9927595(see-also)|pubmed:12917324(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:TnP/raOhk9Hfkp45tH8n+HW1UI07227 rogid:owG+XSUY77mdV1nsAe7eILGxuho7227 intact-crc:D158295EDF90AD0A|rigid:LSVEF3P6cWOjUUEHhMDR0d7IRHk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q05201 uniprotkb:Q05201 intact:EBI-209758|uniprotkb:Q961V4|uniprotkb:Q9VMC1|ensemblmetazoa:FBpp0078964 intact:EBI-209758|uniprotkb:Q961V4|uniprotkb:Q9VMC1|ensemblmetazoa:FBpp0078964 psi-mi:eya_drome(display_long)|uniprotkb:eya(gene name)|psi-mi:eya(display_short)|uniprotkb:cli(gene name synonym)|uniprotkb:CG9554(orf name)|uniprotkb:Protein Clift(gene name synonym) psi-mi:eya_drome(display_long)|uniprotkb:eya(gene name)|psi-mi:eya(display_short)|uniprotkb:cli(gene name synonym)|uniprotkb:CG9554(orf name)|uniprotkb:Protein Clift(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872858 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523492.1|refseq:NP_723188.1|flybase:FBgn0000320|dip:DIP-19253N|ensemblmetazoa:FBgn0000320(gene)|ensemblmetazoa:FBtr0079335(transcript)|go:"GO:0001744"(insect visual primordium formation)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007419"(ventral cord development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008406"(gonad development)|go:"GO:0008584"(male gonad development)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030946"(protein tyrosine phosphatase activity, metal-dependent)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0070285"(pigment cell development)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR006545(EYA)|interpro:IPR028472|interpro:IPR038102|interpro:IPR042577 refseq:NP_523492.1|refseq:NP_723188.1|flybase:FBgn0000320|dip:DIP-19253N|ensemblmetazoa:FBgn0000320(gene)|ensemblmetazoa:FBtr0079335(transcript)|go:"GO:0001744"(insect visual primordium formation)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007419"(ventral cord development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008406"(gonad development)|go:"GO:0008584"(male gonad development)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030946"(protein tyrosine phosphatase activity, metal-dependent)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0070285"(pigment cell development)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR006545(EYA)|interpro:IPR028472|interpro:IPR038102|interpro:IPR042577 pubmed:12917324(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:owG+XSUY77mdV1nsAe7eILGxuho7227 rogid:owG+XSUY77mdV1nsAe7eILGxuho7227 intact-crc:69609A6D6EB5C0E7|rigid:TfdPGuCDlyeTOag29la9Gr4o0TI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09052 uniprotkb:P55824 intact:EBI-134067|uniprotkb:Q24582|uniprotkb:Q8SXU8|uniprotkb:Q9V3Q8|ensemblmetazoa:FBpp0401445|ensemblmetazoa:FBpp0401446|ensemblmetazoa:FBpp0401447 intact:EBI-869561|uniprotkb:Q9V9T6|uniprotkb:Q9Y0Z7|ensemblmetazoa:FBpp0085202 psi-mi:vasa1_drome(display_long)|uniprotkb:vas(gene name)|psi-mi:vas(display_short)|uniprotkb:Antigen Mab46F11(gene name synonym)|uniprotkb:vasa(gene name synonym)|uniprotkb:CG46283(orf name) psi-mi:faf_drome(display_long)|uniprotkb:Ubiquitin-specific-processing protease FAF(gene name synonym)|uniprotkb:Protein fat facets(gene name synonym)|uniprotkb:faf(gene name)|psi-mi:faf(display_short)|uniprotkb:CG1945(orf name)|uniprotkb:Ubiquitin thioesterase FAF(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872862 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283442|refseq:NP_723899.1|refseq:NP_001303322.1|refseq:NP_001260458.1|ensemblmetazoa:FBgn0283442(gene)|rcsb pdb:2IHS|rcsb pdb:3EMW|rcsb pdb:3F2O|rcsb pdb:5NT7|ensemblmetazoa:FBtr0445185(transcript)|ensemblmetazoa:FBtr0445186(transcript)|ensemblmetazoa:FBtr0445187(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0008104"(protein localization)|go:"GO:0030154"(cell differentiation)|go:"GO:0043073"(germ cell nucleus)|go:"GO:0043186"(P granule)|go:"GO:0048477"(oogenesis)|go:"GO:0061803"(posterior cell cortex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|mint:P09052|rcsb pdb:2DB3|dip:DIP-20604N refseq:NP_524612.2|refseq:NP_733455.1|flybase:FBgn0005632|ensemblmetazoa:FBgn0005632(gene)|ensemblmetazoa:FBtr0085843(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007349"(cellularization)|go:"GO:0007601"(visual perception)|go:"GO:0008354"(germ cell migration)|go:"GO:0008583"(mystery cell differentiation)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035192"(nuclear cortical migration)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0048477"(oogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR038765|reactome:R-DME-2173795|reactome:R-DME-5689880|reactome:R-DME-8866652|reactome:R-DME-9013420|reactome:R-DME-9013424|reactome:R-DME-9033241 pubmed:14588248(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:MPzIr/Dex98V189t6FOs8l0nQnM7227 rogid:CjwYV0DymVXfh1K1mM9PWgbfdnc7227 intact-crc:DB6F67639B325E37|rigid:ZP7jmRRKoLHhH4fxXR3vIGJuNjg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KU90 uniprotkb:P55824 intact:EBI-869603|ensemblmetazoa:FBpp0076508|ensemblmetazoa:FBpp0076510 intact:EBI-869561|uniprotkb:Q9V9T6|uniprotkb:Q9Y0Z7|ensemblmetazoa:FBpp0085202 psi-mi:q7ku90_drome(display_long)|uniprotkb:lqf(gene name)|psi-mi:lqf(display_short)|uniprotkb:0110(gene name synonym)|uniprotkb:27(gene name synonym)|uniprotkb:Dmel\CG8532(gene name synonym)|uniprotkb:"E(faf)bE25"(gene name synonym)|uniprotkb:Epsin(gene name synonym)|uniprotkb:LqF(gene name synonym)|uniprotkb:Lqf(gene name synonym)|uniprotkb:anon-WO0118547.239(gene name synonym)|uniprotkb:dEpsin(gene name synonym)|uniprotkb:epsin(gene name synonym)|uniprotkb:"l(3)S011027"(gene name synonym)|uniprotkb:Dmel_CG8532(orf name)|uniprotkb:CG8532(orf name) psi-mi:faf_drome(display_long)|uniprotkb:Ubiquitin-specific-processing protease FAF(gene name synonym)|uniprotkb:Protein fat facets(gene name synonym)|uniprotkb:faf(gene name)|psi-mi:faf(display_short)|uniprotkb:CG1945(orf name)|uniprotkb:Ubiquitin thioesterase FAF(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872866 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523962.2|refseq:NP_729267.1|flybase:FBgn0028582|ensemblmetazoa:FBgn0028582(gene)|ensemblmetazoa:FBtr0076794(transcript)|ensemblmetazoa:FBtr0076796(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0009997"(negative regulation of cardioblast cell fate specification)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal) refseq:NP_524612.2|refseq:NP_733455.1|flybase:FBgn0005632|ensemblmetazoa:FBgn0005632(gene)|ensemblmetazoa:FBtr0085843(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007349"(cellularization)|go:"GO:0007601"(visual perception)|go:"GO:0008354"(germ cell migration)|go:"GO:0008583"(mystery cell differentiation)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035192"(nuclear cortical migration)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0048477"(oogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR038765|reactome:R-DME-2173795|reactome:R-DME-5689880|reactome:R-DME-8866652|reactome:R-DME-9013420|reactome:R-DME-9013424|reactome:R-DME-9033241 pubmed:10725248(see-also)|pubmed:11825870(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NESkuDxxm84z4qw0yji+n7fQLsk7227 rogid:CjwYV0DymVXfh1K1mM9PWgbfdnc7227 intact-crc:FAB15A7DFE3A37D5|rigid:oZkwLo9iOsDVmGTJFnR0l4MJp7M false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24008 uniprotkb:Q9VL78 intact:EBI-195326|uniprotkb:Q9NBV3|ensemblmetazoa:FBpp0071820 intact:EBI-123090|uniprotkb:Q9U4N1|ensemblmetazoa:FBpp0079468|ensemblmetazoa:FBpp0309663 psi-mi:inad_drome(display_long)|uniprotkb:inaD(gene name)|psi-mi:inaD(display_short)|uniprotkb:CG3504(orf name) psi-mi:fkb59_drome(display_long)|uniprotkb:Fkbp59(gene name)|psi-mi:Fkbp59(display_short)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:dFKBP59(gene name synonym)|uniprotkb:CG4535(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872870 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_726260.1|flybase:FBgn0001263|dip:DIP-18621N|ensemblmetazoa:FBgn0001263(gene)|ensemblmetazoa:FBtr0071909(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008104"(protein localization)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0017022"(myosin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031473"(myosin III binding)|go:"GO:0050962"(detection of light stimulus involved in sensory perception)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rcsb pdb:1IHJ|rcsb pdb:2LA8|rcsb pdb:2QKT|rcsb pdb:2QKU|rcsb pdb:2QKV|rcsb pdb:3R0H|rcsb pdb:5F67|rcsb pdb:6IRE|reactome:R-DME-983168 refseq:NP_524895.2|flybase:FBgn0029174|refseq:NP_001285784.1|ensemblmetazoa:FBgn0029174(gene)|ensemblmetazoa:FBtr0079872(transcript)|ensemblmetazoa:FBtr0342837(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 pubmed:11514552(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:A8GcGpwkZoLFwA/GoYkveOsUzC07227 rogid:soxcv6VDkXWWU6WqKagLDL5sBog7227 intact-crc:A76986EA4E33BD07|rigid:vuu8PASM0HFxaDl6+oEXAeCTD+I false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P05661 uniprotkb:P35554 intact:EBI-195031|uniprotkb:O18392|uniprotkb:O18393|uniprotkb:Q24412|uniprotkb:Q7JN62|uniprotkb:Q7JN63|uniprotkb:Q7JQ08|uniprotkb:Q7JQ09|uniprotkb:Q7M4K4|uniprotkb:Q8INZ9|uniprotkb:Q8IP00|uniprotkb:Q8IP01|uniprotkb:Q8IP02|uniprotkb:Q8IP03|uniprotkb:Q8IP04|uniprotkb:Q8IP05|uniprotkb:Q8IP06|uniprotkb:Q8IP07|uniprotkb:Q8IP08|uniprotkb:Q8IP09|uniprotkb:Q8IP10|uniprotkb:Q9TY21|uniprotkb:Q9TY22|uniprotkb:Q9TYD7|uniprotkb:Q9VJI3 intact:EBI-869611|uniprotkb:Q9VW65|ensemblmetazoa:FBpp0074679|ensemblmetazoa:FBpp0304969 psi-mi:mysa_drome(display_long)|uniprotkb:Mhc(gene name)|psi-mi:Mhc(display_short)|uniprotkb:CG17927(orf name) psi-mi:ftn_drome(display_long)|uniprotkb:Muscle protein 27(gene name synonym)|uniprotkb:fln(gene name)|psi-mi:fln(display_short)|uniprotkb:FTN(gene name synonym)|uniprotkb:mp27(gene name synonym)|uniprotkb:CG7445(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872874 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162991.1|refseq:NP_523587.4|refseq:NP_723999.1|refseq:NP_724000.1|refseq:NP_724001.1|refseq:NP_724003.1|refseq:NP_724004.1|refseq:NP_724005.1|refseq:NP_724006.1|refseq:NP_724007.1|refseq:NP_724008.1|refseq:NP_724009.1|refseq:NP_724010.1|refseq:NP_724002.2|flybase:FBgn0264695|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007517"(muscle organ development)|go:"GO:0007527"(adult somatic muscle development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0030017"(sarcomere)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031033"(myosin filament organization)|go:"GO:0031672"(A band)|go:"GO:0040011"(locomotion)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060361"(flight)|go:"GO:0071689"(muscle thin filament assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P05661|rcsb pdb:5W1A refseq:NP_524174.1|flybase:FBgn0005633|refseq:NP_001262084.1|ensemblmetazoa:FBgn0005633(gene)|ensemblmetazoa:FBtr0074910(transcript)|ensemblmetazoa:FBtr0332723(transcript)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0007527"(adult somatic muscle development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014703"(oscillatory muscle contraction)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031672"(A band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0097493"(structural molecule activity conferring elasticity) pubmed:8486738(see-also)|pubmed:11134077(see-also)|pubmed:12663941(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:PjIC1oHiwbQEdum3SDZnk/b7O5E7227 rogid:UM67qGMdLOYEwZiUMPuxEyU8R0E7227 intact-crc:35C7CF92BBED777F|rigid:wofieO/doiMFLs68WyQf93BRIgw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P12982 uniprotkb:P48462 intact:EBI-152633|uniprotkb:Q4PIY5|uniprotkb:Q9VG75|ensemblmetazoa:FBpp0082067 intact:EBI-869621|uniprotkb:Q9W2V5|ensemblmetazoa:FBpp0071382|ensemblmetazoa:FBpp0305497 psi-mi:pp12_drome(display_long)|uniprotkb:Pp1-87B(gene name)|psi-mi:Pp1-87B(display_short)|uniprotkb:CG5650(orf name) psi-mi:pp1b_drome(display_long)|uniprotkb:Protein flap wing(gene name synonym)|uniprotkb:flw(gene name)|psi-mi:flw(display_short)|uniprotkb:PP1-9C(gene name synonym)|uniprotkb:PP1-BETA-9C(gene name synonym)|uniprotkb:CG2096(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872878 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524937.1|flybase:FBgn0004103|ensemblmetazoa:FBgn0004103(gene)|ensemblmetazoa:FBtr0082595(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007611"(learning or memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008355"(olfactory learning)|go:"GO:0008542"(visual learning)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030261"(chromosome condensation)|go:"GO:0040011"(locomotion)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|go:"GO:0005737"(cytoplasm)|reactome:R-DME-350416|reactome:R-DME-350480|reactome:R-DME-538898|go:"GO:0005700"(polytene chromosome)|dip:DIP-18465N refseq:NP_524738.1|flybase:FBgn0000711|refseq:NP_001259407.1|ensemblmetazoa:FBgn0000711(gene)|ensemblmetazoa:FBtr0071447(transcript)|ensemblmetazoa:FBtr0333305(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0007312"(oocyte nucleus migration involved in oocyte dorsal/ventral axis specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0014706"(striated muscle tissue development)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:1905330"(regulation of morphogenesis of an epithelium)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|reactome:R-DME-2565942|reactome:R-DME-350416|reactome:R-DME-350480|reactome:R-DME-538898|reactome:R-DME-5625740|reactome:R-DME-5627123 pubmed:12134149(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:wYZDYWZEbdafO7gAM+avnFnIF9Q7227 rogid:PZSfwmpwqFs81zLVfparcg1xIZY7227 intact-crc:82F527E6A030F60C|rigid:q89YE5iBM6CtvClvXD8wD1DXY1E false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9V3C7 uniprotkb:P48462 intact:EBI-95729|ensemblmetazoa:FBpp0076099 intact:EBI-869621|uniprotkb:Q9W2V5|ensemblmetazoa:FBpp0071382|ensemblmetazoa:FBpp0305497 psi-mi:q9v3c7_drome(display_long)|uniprotkb:I-2(gene name)|psi-mi:I-2(display_short)|uniprotkb:inhibitor-2(gene name synonym)|uniprotkb:I-2Dm(gene name synonym)|uniprotkb:Dmel_CG10574(orf name)|uniprotkb:DI-2(gene name synonym)|uniprotkb:Dm I-2(gene name synonym)|uniprotkb:Dmel\CG10574(gene name synonym)|uniprotkb:I-2PP1(gene name synonym)|uniprotkb:SET(gene name synonym)|uniprotkb:CG10574(orf name) psi-mi:pp1b_drome(display_long)|uniprotkb:Protein flap wing(gene name synonym)|uniprotkb:flw(gene name)|psi-mi:flw(display_short)|uniprotkb:PP1-9C(gene name synonym)|uniprotkb:PP1-BETA-9C(gene name synonym)|uniprotkb:CG2096(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872882 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524013.1|flybase:FBgn0028429|ensemblmetazoa:FBgn0028429(gene)|ensemblmetazoa:FBtr0076370(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007062("Protein phosphatase inhibitor 2 (IPP-2)") refseq:NP_524738.1|flybase:FBgn0000711|refseq:NP_001259407.1|ensemblmetazoa:FBgn0000711(gene)|ensemblmetazoa:FBtr0071447(transcript)|ensemblmetazoa:FBtr0333305(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0007312"(oocyte nucleus migration involved in oocyte dorsal/ventral axis specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0014706"(striated muscle tissue development)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:1905330"(regulation of morphogenesis of an epithelium)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|reactome:R-DME-2565942|reactome:R-DME-350416|reactome:R-DME-350480|reactome:R-DME-538898|reactome:R-DME-5625740|reactome:R-DME-5627123 pubmed:10587451(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Ags55wNBOzMzDZSeYLLaXPA8Ovw7227 rogid:PZSfwmpwqFs81zLVfparcg1xIZY7227 intact-crc:AF562B33F1B76E92|rigid:5cx66AGjyMoF4h5IoSGxNehygyw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07207 uniprotkb:Q24342 intact:EBI-103438|uniprotkb:O97458|uniprotkb:P04154|uniprotkb:Q9W4T8|ensemblmetazoa:FBpp0070483|ensemblmetazoa:FBpp0293201 intact:EBI-192182|uniprotkb:Q9VP97|ensemblmetazoa:FBpp0077925 psi-mi:notch_drome(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:CG3936(orf name) psi-mi:fng_drome(display_long)|uniprotkb:fng(gene name)|psi-mi:fng(display_short)|uniprotkb:CG10580(orf name)|uniprotkb:O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872886 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476859.2|flybase:FBgn0004647|ensemblmetazoa:FBgn0004647(gene)|ensemblmetazoa:FBtr0070507(transcript)|ensemblmetazoa:FBtr0304659(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002213"(defense response to insect)|go:"GO:0003682"(chromatin binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007391"(dorsal closure)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009608"(response to symbiont)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0022416"(chaeta development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0007498"(mesoderm development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0007616"(long-term memory)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0040008"(regulation of growth)|go:"GO:0042686"(regulation of cardioblast cell fate specification)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045316"(negative regulation of compound eye photoreceptor development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048627"(myoblast development)|go:"GO:0048664"(neuron fate determination)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050699"(WW domain binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0060289"(compartment boundary maintenance)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990433"(CSL-Notch-Mastermind transcription factor complex)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1OT8|rcsb pdb:2JMF|refseq:NP_001245510.1|dip:DIP-5N refseq:NP_524191.1|flybase:FBgn0011591|ensemblmetazoa:FBgn0011591(gene)|ensemblmetazoa:FBtr0078267(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0006486"(protein glycosylation)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0033829"(O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048749"(compound eye development)|interpro:IPR003378(Fringe-like)|interpro:IPR017374(Fringe) pubmed:10935626(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:T1iHJGMHXkhxbFRybmSDlizN7oQ7227 rogid:616UHwuLAOTkM5jHeg7RlydgiVw7227 intact-crc:47C4132D5CED15A9|rigid:e0O6bv4xH7T6b0rq2/a4JUzHEZ4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08928 uniprotkb:P25028 intact:EBI-188444|uniprotkb:Q9VMQ0|ensemblmetazoa:FBpp0078733|ensemblmetazoa:FBpp0297901|ensemblmetazoa:FBpp0297902|ensemblmetazoa:FBpp0312110 intact:EBI-106103|uniprotkb:Q8T057|uniprotkb:Q9W4W0|uniprotkb:Q9W4W1|ensemblmetazoa:FBpp0070463 psi-mi:lam0_drome(display_long)|uniprotkb:Lam(gene name)|psi-mi:Lam(display_short)|uniprotkb:CG6944(orf name) psi-mi:fsya_drome(display_long)|uniprotkb:"fs(1)Ya"(gene name)|psi-mi:"fs(1)Ya"(display_short)|uniprotkb:CG2707(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872894 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476616.1|flybase:FBgn0002525|refseq:NP_001245892.1|refseq:NP_001245893.1|refseq:NP_001285629.1|dip:DIP-2663N|ensemblmetazoa:FBgn0002525(gene)|ensemblmetazoa:FBtr0079100(transcript)|ensemblmetazoa:FBtr0307058(transcript)|ensemblmetazoa:FBtr0307059(transcript)|ensemblmetazoa:FBtr0346460(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007097"(nuclear migration)|go:"GO:0007110"(meiosis I cytokinesis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007569"(cell aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0048137"(spermatocyte division)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:2000433"(positive regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-DME-352238|reactome:R-DME-4419969|reactome:R-DME-9013405|reactome:R-DME-9035034 ensemblmetazoa:FBgn0000927(gene)|ensemblmetazoa:FBtr0070485(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006997"(nucleus organization)|go:"GO:0007344"(pronuclear fusion)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)|refseq:NP_477493.2|flybase:FBgn0000927|dip:DIP-115N pubmed:12679383(see-also)|pubmed:9632815(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Kuv16J8T6uZ7lIJaqjVrdn9x5WU7227 rogid:zhZCbl2NOBca2tb8+Ov6M2KicW07227 intact-crc:3CCCD4E096B5AD45|rigid:mFHp2X+QayPG+gPtbb60dhaWI94 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P02283 uniprotkb:P25028 intact:EBI-188137|uniprotkb:Q4ABE1|uniprotkb:Q9W5U7|ensemblmetazoa:FBpp0085281|ensemblmetazoa:FBpp0091113|ensemblmetazoa:FBpp0091115|ensemblmetazoa:FBpp0091117|ensemblmetazoa:FBpp0091119|ensemblmetazoa:FBpp0091121|ensemblmetazoa:FBpp0091123|ensemblmetazoa:FBpp0091125|ensemblmetazoa:FBpp0091127|ensemblmetazoa:FBpp0091129|ensemblmetazoa:FBpp0091131|ensemblmetazoa:FBpp0091133|ensemblmetazoa:FBpp0091135|ensemblmetazoa:FBpp0091137|ensemblmetazoa:FBpp0091139|ensemblmetazoa:FBpp0091141|ensemblmetazoa:FBpp0091143|ensemblmetazoa:FBpp0091145|ensemblmetazoa:FBpp0091147|ensemblmetazoa:FBpp0091149|ensemblmetazoa:FBpp0091151|ensemblmetazoa:FBpp0091153|ensemblmetazoa:FBpp0091155 intact:EBI-106103|uniprotkb:Q8T057|uniprotkb:Q9W4W0|uniprotkb:Q9W4W1|ensemblmetazoa:FBpp0070463 psi-mi:h2b_drome(display_long)|uniprotkb:His2B(gene name)|psi-mi:His2B(display_short)|uniprotkb:"His2B:CG17949"(gene name)|psi-mi:"His2B:CG17949"(display_short)|uniprotkb:"His2B:CG33868"(gene name)|psi-mi:"His2B:CG33868"(display_short)|uniprotkb:"His2B:CG33870"(gene name)|psi-mi:"His2B:CG33870"(display_short)|uniprotkb:"His2B:CG33872"(gene name)|psi-mi:"His2B:CG33872"(display_short)|uniprotkb:"His2B:CG33874"(gene name)|psi-mi:"His2B:CG33874"(display_short)|uniprotkb:"His2B:CG33876"(gene name)|psi-mi:"His2B:CG33876"(display_short)|uniprotkb:"His2B:CG33878"(gene name)|psi-mi:"His2B:CG33878"(display_short)|uniprotkb:"His2B:CG33880"(gene name)|psi-mi:"His2B:CG33880"(display_short)|uniprotkb:"His2B:CG33882"(gene name)|psi-mi:"His2B:CG33882"(display_short)|uniprotkb:"His2B:CG33884"(gene name)|psi-mi:"His2B:CG33884"(display_short)|uniprotkb:"His2B:CG33886"(gene name)|psi-mi:"His2B:CG33886"(display_short)|uniprotkb:"His2B:CG33888"(gene name)|psi-mi:"His2B:CG33888"(display_short)|uniprotkb:"His2B:CG33890"(gene name)|psi-mi:"His2B:CG33890"(display_short)|uniprotkb:"His2B:CG33892"(gene name)|psi-mi:"His2B:CG33892"(display_short)|uniprotkb:"His2B:CG33894"(gene name)|psi-mi:"His2B:CG33894"(display_short)|uniprotkb:"His2B:CG33896"(gene name)|psi-mi:"His2B:CG33896"(display_short)|uniprotkb:"His2B:CG33898"(gene name)|psi-mi:"His2B:CG33898"(display_short)|uniprotkb:"His2B:CG33900"(gene name)|psi-mi:"His2B:CG33900"(display_short)|uniprotkb:"His2B:CG33902"(gene name)|psi-mi:"His2B:CG33902"(display_short)|uniprotkb:"His2B:CG33904"(gene name)|psi-mi:"His2B:CG33904"(display_short)|uniprotkb:"His2B:CG33906"(gene name)|psi-mi:"His2B:CG33906"(display_short)|uniprotkb:"His2B:CG33908"(gene name)|psi-mi:"His2B:CG33908"(display_short)|uniprotkb:"His2B:CG33910"(gene name)|psi-mi:"His2B:CG33910"(display_short)|uniprotkb:CG17949(orf name)|uniprotkb:CG33868(orf name)|uniprotkb:CG33870(orf name)|uniprotkb:CG33872(orf name)|uniprotkb:CG33874(orf name)|uniprotkb:CG33876(orf name)|uniprotkb:CG33878(orf name)|uniprotkb:CG33880(orf name)|uniprotkb:CG33882(orf name)|uniprotkb:CG33884(orf name)|uniprotkb:CG33886(orf name)|uniprotkb:CG33888(orf name)|uniprotkb:CG33890(orf name)|uniprotkb:CG33892(orf name)|uniprotkb:CG33894(orf name)|uniprotkb:CG33896(orf name)|uniprotkb:CG33898(orf name)|uniprotkb:CG33900(orf name)|uniprotkb:CG33902(orf name)|uniprotkb:CG33904(orf name)|uniprotkb:CG33906(orf name)|uniprotkb:CG33908(orf name)|uniprotkb:CG33910(orf name) psi-mi:fsya_drome(display_long)|uniprotkb:"fs(1)Ya"(gene name)|psi-mi:"fs(1)Ya"(display_short)|uniprotkb:CG2707(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872898 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027283.1|refseq:NP_001027287.1|refseq:NP_001027291.1|refseq:NP_001027296.1|refseq:NP_001027300.1|refseq:NP_001027305.1|refseq:NP_001027310.1|refseq:NP_001027315.1|refseq:NP_001027320.1|refseq:NP_001027325.1|refseq:NP_001027330.1|refseq:NP_001027335.1|refseq:NP_001027340.1|refseq:NP_001027345.1|refseq:NP_001027350.1|refseq:NP_001027355.1|refseq:NP_001027360.1|refseq:NP_001027365.1|refseq:NP_001027370.1|refseq:NP_001027375.1|refseq:NP_001027380.1|refseq:NP_001027385.1|refseq:NP_724342.1|flybase:FBgn0001198|flybase:FBgn0061209|flybase:FBgn0053868|flybase:FBgn0053870|flybase:FBgn0053872|flybase:FBgn0053874|flybase:FBgn0053876|flybase:FBgn0053878|flybase:FBgn0053880|flybase:FBgn0053882|flybase:FBgn0053884|flybase:FBgn0053886|flybase:FBgn0053888|flybase:FBgn0053890|flybase:FBgn0053892|flybase:FBgn0053894|flybase:FBgn0053896|flybase:FBgn0053898|flybase:FBgn0053900|flybase:FBgn0053902|flybase:FBgn0053904|flybase:FBgn0053906|flybase:FBgn0053908|flybase:FBgn0053910|dip:DIP-22804N|ensemblmetazoa:FBgn0053886(gene)|ensemblmetazoa:FBgn0053888(gene)|ensemblmetazoa:FBgn0053890(gene)|ensemblmetazoa:FBgn0053892(gene)|ensemblmetazoa:FBgn0053894(gene)|ensemblmetazoa:FBgn0053896(gene)|ensemblmetazoa:FBgn0053898(gene)|ensemblmetazoa:FBgn0053900(gene)|ensemblmetazoa:FBgn0053902(gene)|ensemblmetazoa:FBgn0053904(gene)|ensemblmetazoa:FBgn0053906(gene)|ensemblmetazoa:FBgn0053908(gene)|ensemblmetazoa:FBgn0053910(gene)|ensemblmetazoa:FBgn0061209(gene)|ensemblmetazoa:FBtr0085927(transcript)|ensemblmetazoa:FBtr0091872(transcript)|ensemblmetazoa:FBtr0091874(transcript)|ensemblmetazoa:FBtr0091876(transcript)|ensemblmetazoa:FBtr0091878(transcript)|ensemblmetazoa:FBtr0091880(transcript)|ensemblmetazoa:FBtr0091882(transcript)|ensemblmetazoa:FBtr0091884(transcript)|ensemblmetazoa:FBtr0091886(transcript)|ensemblmetazoa:FBtr0091888(transcript)|ensemblmetazoa:FBtr0091890(transcript)|ensemblmetazoa:FBtr0091892(transcript)|ensemblmetazoa:FBtr0091894(transcript)|ensemblmetazoa:FBtr0091896(transcript)|ensemblmetazoa:FBtr0091898(transcript)|ensemblmetazoa:FBtr0091900(transcript)|ensemblmetazoa:FBtr0091902(transcript)|ensemblmetazoa:FBtr0091904(transcript)|ensemblmetazoa:FBtr0091906(transcript)|ensemblmetazoa:FBtr0091908(transcript)|ensemblmetazoa:FBtr0091910(transcript)|ensemblmetazoa:FBtr0091912(transcript)|ensemblmetazoa:FBtr0091914(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02283|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:4QLC|rcsb pdb:4X23|rcsb pdb:5CVE|rcsb pdb:5WCU|rcsb pdb:6DZT|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-3214847|reactome:R-DME-5689880|reactome:R-DME-8866654|reactome:R-DME-8936459|ensemblmetazoa:FBgn0053868(gene)|ensemblmetazoa:FBgn0053870(gene)|ensemblmetazoa:FBgn0053872(gene)|ensemblmetazoa:FBgn0053874(gene)|ensemblmetazoa:FBgn0053876(gene)|ensemblmetazoa:FBgn0053878(gene)|ensemblmetazoa:FBgn0053880(gene)|ensemblmetazoa:FBgn0053882(gene)|ensemblmetazoa:FBgn0053884(gene) ensemblmetazoa:FBgn0000927(gene)|ensemblmetazoa:FBtr0070485(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006997"(nucleus organization)|go:"GO:0007344"(pronuclear fusion)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)|refseq:NP_477493.2|flybase:FBgn0000927|dip:DIP-115N pubmed:11854412(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KuGc2Ovj9eNDpjfoKjx7mAA/g+E7227 rogid:zhZCbl2NOBca2tb8+Ov6M2KicW07227 intact-crc:DA3EA6F000ED35B4|rigid:ZZpT8fctzxEx3lHW52UOd0aKNHs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P52295 uniprotkb:O18388 intact:EBI-145898|uniprotkb:Q24431|uniprotkb:Q95R96|uniprotkb:Q9VL45|ensemblmetazoa:FBpp0079527 intact:EBI-155558|uniprotkb:Q540Y0|uniprotkb:Q9V3E6|ensemblmetazoa:FBpp0080922|ensemblmetazoa:FBpp0294035|ensemblmetazoa:FBpp0294036|ensemblmetazoa:FBpp0294037|ensemblmetazoa:FBpp0294038 psi-mi:ima_drome(display_long)|uniprotkb:Pen(gene name)|psi-mi:Pen(display_short)|uniprotkb:CG4799(orf name)|uniprotkb:Pendulin(gene name synonym)|uniprotkb:Karyopherin subunit alpha(gene name synonym) psi-mi:imb_drome(display_long)|uniprotkb:"Fs(2)Ket"(gene name)|psi-mi:"Fs(2)Ket"(display_short)|uniprotkb:CG2637(orf name)|uniprotkb:Karyopherin subunit beta(gene name synonym)|uniprotkb:Protein ketel(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872902 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477041.1|dip:DIP-17105N|go:"GO:0048542"(lymph gland development)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|reactome:R-DME-5693548|ensemblmetazoa:FBgn0267727(gene)|ensemblmetazoa:FBtr0079937(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007291"(sperm individualization)|go:"GO:0007301"(female germline ring canal formation)|go:"GO:0042332"(gravitaxis)|flybase:FBgn0287720 refseq:NP_001246108.1|refseq:NP_001246109.1|refseq:NP_001246110.1|refseq:NP_001246111.1|refseq:NP_477496.1|flybase:FBgn0262743|dip:DIP-23049N|ensemblmetazoa:FBgn0262743(gene)|ensemblmetazoa:FBtr0081392(transcript)|ensemblmetazoa:FBtr0305584(transcript)|ensemblmetazoa:FBtr0305585(transcript)|ensemblmetazoa:FBtr0305586(transcript)|ensemblmetazoa:FBtr0305587(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043186"(P granule)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:O18388|reactome:R-DME-140342|reactome:R-DME-1655829|reactome:R-DME-2995383|reactome:R-DME-6798695|reactome:R-DME-909733 pubmed:10882518(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:EmTbVo4vLA06arpd8xmxacQBdwk7227 rogid:aOINvxY8YoLIUhNwXg/7We/Vvtg7227 intact-crc:F47D37F69631764A|rigid:hWhDQUDSy+fV8k5k4CbUOmLk4SY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O76522 uniprotkb:O18388 intact:EBI-499003 intact:EBI-155558|uniprotkb:Q540Y0|uniprotkb:Q9V3E6|ensemblmetazoa:FBpp0080922|ensemblmetazoa:FBpp0294035|ensemblmetazoa:FBpp0294036|ensemblmetazoa:FBpp0294037|ensemblmetazoa:FBpp0294038 psi-mi:o76522_drome(display_long)|uniprotkb:CG9423(orf name)|uniprotkb:Kap-alpha3(gene name)|psi-mi:Kap-alpha3(display_short)|uniprotkb:Kap-alpha-3(gene name synonym) psi-mi:imb_drome(display_long)|uniprotkb:"Fs(2)Ket"(gene name)|psi-mi:"Fs(2)Ket"(display_short)|uniprotkb:CG2637(orf name)|uniprotkb:Karyopherin subunit beta(gene name synonym)|uniprotkb:Protein ketel(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872906 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0027338|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0009411"(response to UV)|go:"GO:0017022"(myosin binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975 refseq:NP_001246108.1|refseq:NP_001246109.1|refseq:NP_001246110.1|refseq:NP_001246111.1|refseq:NP_477496.1|flybase:FBgn0262743|dip:DIP-23049N|ensemblmetazoa:FBgn0262743(gene)|ensemblmetazoa:FBtr0081392(transcript)|ensemblmetazoa:FBtr0305584(transcript)|ensemblmetazoa:FBtr0305585(transcript)|ensemblmetazoa:FBtr0305586(transcript)|ensemblmetazoa:FBtr0305587(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043186"(P granule)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:O18388|reactome:R-DME-140342|reactome:R-DME-1655829|reactome:R-DME-2995383|reactome:R-DME-6798695|reactome:R-DME-909733 pubmed:10882518(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Ry3o76SK18N9E4hRVDYUCOJl6U07227 rogid:aOINvxY8YoLIUhNwXg/7We/Vvtg7227 intact-crc:E9F0FD414E0D8420|rigid:CvajS8xwE7RMbVQZtBL5zFbqpXE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42282 uniprotkb:P02835 intact:EBI-77008|uniprotkb:A4V3Q3|uniprotkb:Q0KHY0|uniprotkb:Q1LZ43|uniprotkb:Q24313|uniprotkb:Q9V9V2|ensemblmetazoa:FBpp0085186|ensemblmetazoa:FBpp0085188|ensemblmetazoa:FBpp0085190|ensemblmetazoa:FBpp0292319 intact:EBI-125786|uniprotkb:O96929|uniprotkb:Q4V6Y3|uniprotkb:Q9V3W3|ensemblmetazoa:FBpp0081139 psi-mi:ttka_drome(display_long)|uniprotkb:ttk(gene name)|psi-mi:ttk(display_short)|uniprotkb:FTZ-F2(gene name synonym)|uniprotkb:CG1856(orf name)|uniprotkb:Tramtrack p88(gene name synonym)|uniprotkb:Repressor protein fushi tarazu(gene name synonym) psi-mi:ftz_drome(display_long)|uniprotkb:ftz(gene name)|psi-mi:ftz(display_short)|uniprotkb:CG2047(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872914 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189329.1|refseq:NP_733443.1|refseq:NP_733444.1|refseq:NP_733445.1|flybase:FBgn0003870|ensemblmetazoa:FBgn0003870(gene)|ensemblmetazoa:FBtr0085825(transcript)|ensemblmetazoa:FBtr0085827(transcript)|ensemblmetazoa:FBtr0085829(transcript)|ensemblmetazoa:FBtr0303227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031208"(POZ domain binding)|go:"GO:0035001"(dorsal trunk growth, open tracheal system)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035151"(regulation of tube size, open tracheal system)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042682"(regulation of compound eye cone cell fate specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045677"(negative regulation of R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048053"(R1/R6 development)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048750"(compound eye corneal lens morphogenesis)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 refseq:NP_477498.1|flybase:FBgn0001077|ensemblmetazoa:FBgn0001077(gene)|ensemblmetazoa:FBtr0081625(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007417"(central nervous system development)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0008354"(germ cell migration)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035282"(segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR005567(Fushi tarazu, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1FTZ|rcsb pdb:2XHS|dip:DIP-18500N pubmed:10381570(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:k0MeF2/ch3ddqz7uLHjP8aeJwoI7227 rogid:Kvf67LQf7eGvmUDSnAlxn8/kSwU7227 intact-crc:634F3C6B986AA122|rigid:JDOS3QicKhYh3euJz3XrtfWxFto false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P32030 uniprotkb:P02835 intact:EBI-183822|intact:EBI-1628505|uniprotkb:Q9VQV4 intact:EBI-125786|uniprotkb:O96929|uniprotkb:Q4V6Y3|uniprotkb:Q9V3W3|ensemblmetazoa:FBpp0081139 psi-mi:slp1_drome(display_long)|uniprotkb:slp1(gene name)|psi-mi:slp1(display_short)|uniprotkb:FD6(gene name synonym)|uniprotkb:CG16738(orf name)|uniprotkb:Sloppy paired locus protein 1(gene name synonym) psi-mi:ftz_drome(display_long)|uniprotkb:ftz(gene name)|psi-mi:ftz(display_short)|uniprotkb:CG2047(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872918 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476730.1|flybase:FBgn0003430|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007380"(specification of segmental identity, head)|go:"GO:0007507"(heart development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0060914"(heart formation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390 refseq:NP_477498.1|flybase:FBgn0001077|ensemblmetazoa:FBgn0001077(gene)|ensemblmetazoa:FBtr0081625(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007417"(central nervous system development)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0008354"(germ cell migration)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035282"(segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR005567(Fushi tarazu, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1FTZ|rcsb pdb:2XHS|dip:DIP-18500N pubmed:10381570(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:uebOFSa00gfCnbGKVhNpUz35rgI7227 rogid:Kvf67LQf7eGvmUDSnAlxn8/kSwU7227 intact-crc:7A5B12E372080B54|rigid:3mYU8S3NNldzhJ88ebCAZnHo0Yg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P06601 uniprotkb:P02835 intact:EBI-254508|uniprotkb:Q9VKB6|ensemblmetazoa:FBpp0079882 intact:EBI-125786|uniprotkb:O96929|uniprotkb:Q4V6Y3|uniprotkb:Q9V3W3|ensemblmetazoa:FBpp0081139 psi-mi:prd_drome(display_long)|uniprotkb:prd(gene name)|psi-mi:prd(display_short)|uniprotkb:CG6716(orf name) psi-mi:ftz_drome(display_long)|uniprotkb:ftz(gene name)|psi-mi:ftz(display_short)|uniprotkb:CG2047(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872922 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523556.1|refseq:NP_723721.1|flybase:FBgn0003145|dip:DIP-22888N|ensemblmetazoa:FBgn0003145(gene)|ensemblmetazoa:FBtr0080298(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|rcsb pdb:1FJL|rcsb pdb:1PDN|reactome:R-DME-3214847 refseq:NP_477498.1|flybase:FBgn0001077|ensemblmetazoa:FBgn0001077(gene)|ensemblmetazoa:FBtr0081625(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007417"(central nervous system development)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0008354"(germ cell migration)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035282"(segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR005567(Fushi tarazu, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1FTZ|rcsb pdb:2XHS|dip:DIP-18500N pubmed:8538765(see-also)|pubmed:8095092(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:hab+069Bmgz4DDY0kUHA+b+hObM7227 rogid:Kvf67LQf7eGvmUDSnAlxn8/kSwU7227 intact-crc:C458E06AE1670236|rigid:rOMbaXymRxrhzi53GqYmtK5tr9A false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P33244 uniprotkb:P02835 intact:EBI-160447|ensemblmetazoa:FBpp0074853|uniprotkb:Q24538|uniprotkb:Q8IQT5|uniprotkb:Q960U2|uniprotkb:Q9VVS8|uniprotkb:B9EQU1 intact:EBI-125786|uniprotkb:O96929|uniprotkb:Q4V6Y3|uniprotkb:Q9V3W3|ensemblmetazoa:FBpp0081139 psi-mi:ftzf1_drome(display_long)|uniprotkb:ftz-f1(gene name)|psi-mi:ftz-f1(display_short)|uniprotkb:NR5A3(gene name synonym)|uniprotkb:CG4059(orf name)|uniprotkb:FTZ-F1 alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 5 group A member 3(gene name synonym) psi-mi:ftz_drome(display_long)|uniprotkb:ftz(gene name)|psi-mi:ftz(display_short)|uniprotkb:CG2047(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872926 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524143.2|refseq:NP_730359.1|flybase:FBgn0001078|ensemblmetazoa:FBgn0001078(gene)|ensemblmetazoa:FBtr0075086(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002165"(instar larval or pupal development)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007552"(metamorphosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008219"(cell death)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009888"(tissue development)|go:"GO:0016319"(mushroom body development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0035073"(pupariation)|go:"GO:0035074"(pupation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035626"(juvenile hormone mediated signaling pathway)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016355(Orphan nuclear receptor Fushi-tarazu factor 1)|interpro:IPR035500|rcsb pdb:2XHS|reactome:R-DME-383280|reactome:R-DME-4090294|refseq:NP_001246824.1 refseq:NP_477498.1|flybase:FBgn0001077|ensemblmetazoa:FBgn0001077(gene)|ensemblmetazoa:FBtr0081625(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007417"(central nervous system development)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0008354"(germ cell migration)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035282"(segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR005567(Fushi tarazu, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1FTZ|rcsb pdb:2XHS|dip:DIP-18500N pubmed:9020364(see-also)|pubmed:9043065(see-also)|pubmed:9020363(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:m/yxQjjm37/IaCCpLPpZFwPPV+c7227 rogid:Kvf67LQf7eGvmUDSnAlxn8/kSwU7227 intact-crc:A86DB8850E8F6941|rigid:ONre2Kh2sJnVzLxIFWeW/jJz6/o false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q27279 uniprotkb:P23647 intact:EBI-496967 intact:EBI-165536|ensemblmetazoa:FBpp0074373|uniprotkb:Q26346|uniprotkb:Q26347|uniprotkb:Q27412|uniprotkb:Q9VWR7 psi-mi:q27279_drome(display_long)|uniprotkb:CG6054(orf name)|uniprotkb:"Su(fu)"(gene name)|psi-mi:"Su(fu)"(display_short)|uniprotkb:suppressor of fused(gene name synonym) psi-mi:fused_drome(display_long)|uniprotkb:fu(gene name)|psi-mi:fu(display_short)|uniprotkb:CG6551(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872930 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0005355|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-DME-209159|reactome:R-DME-216119 ensemblmetazoa:FBgn0001079(gene)|ensemblmetazoa:FBtr0074602(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007228"(positive regulation of hh target transcription factor activity)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007367"(segment polarity determination)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0005119"(smoothened binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6LPH|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-216119|reactome:R-DME-216217|refseq:NP_477499.1|flybase:FBgn0001079|dip:DIP-492N pubmed:9601642(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:kJht+zz+5JAYtNJQ1IX1hW480e47227 rogid:5KrFb8xuGHpjwIlFMx4AkeD9/m47227 intact-crc:B089410716A61512|rigid:KHpcqOzH1MXIlDRJ4vRVAhA4lMg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P28465 uniprotkb:P18537 intact:EBI-869633|uniprotkb:Q86PC8|uniprotkb:Q9V584|ensemblmetazoa:FBpp0087596 intact:EBI-251576|uniprotkb:Q9VUE0|uniprotkb:Q9VUE2|intact:EBI-251599|ensemblmetazoa:FBpp0075485 psi-mi:wnt2_drome(display_long)|uniprotkb:dWnt-2(gene name synonym)|uniprotkb:Wnt2(gene name)|psi-mi:Wnt2(display_short)|uniprotkb:Wnt-2(gene name synonym)|uniprotkb:CG1916(orf name) psi-mi:friz_drome(display_long)|uniprotkb:fz(gene name)|psi-mi:fz(display_short)|uniprotkb:CG17697(orf name)|uniprotkb:Frizzled-1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872938 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476810.1|flybase:FBgn0004360|ensemblmetazoa:FBgn0004360(gene)|ensemblmetazoa:FBtr0088512(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048675"(axon extension)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR043158|reactome:R-DME-3238698 refseq:NP_524812.1|flybase:FBgn0001085|dip:DIP-22727N|ensemblmetazoa:FBgn0001085(gene)|ensemblmetazoa:FBtr0075743(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0007494"(midgut development)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035320"(imaginal disc-derived wing hair site selection)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0042685"(cardioblast cell fate specification)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048675"(axon extension)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026552|interpro:IPR036790|reactome:R-DME-209387|reactome:R-DME-209440|reactome:R-DME-209472|reactome:R-DME-350368|reactome:R-DME-350376|reactome:R-DME-350379|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086398|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641262|reactome:R-DME-5140745 pubmed:12205098(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:4bsdFt58cDSXk5mgtety27IEE2E7227 rogid:4tfZSq+RV6xKUPYq7P2V6Nkvzxs7227 intact-crc:333614C47D07F7CE|rigid:6/RsMUkPg/Qg7d/2kLyKEQ1583k false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09615 uniprotkb:P18537 intact:EBI-98242|uniprotkb:Q27768|uniprotkb:Q27769|uniprotkb:Q8IPI1|uniprotkb:Q8MQP9|uniprotkb:Q9VM27|ensemblmetazoa:FBpp0079060 intact:EBI-251576|uniprotkb:Q9VUE0|uniprotkb:Q9VUE2|intact:EBI-251599|ensemblmetazoa:FBpp0075485 psi-mi:wntg_drome(display_long)|uniprotkb:Protein Wnt-1(gene name synonym)|uniprotkb:Protein int-1(gene name synonym)|uniprotkb:CG4889(orf name)|uniprotkb:wg(gene name)|psi-mi:wg(display_short)|uniprotkb:dWnt-1(gene name synonym)|uniprotkb:dInt-1(gene name synonym) psi-mi:friz_drome(display_long)|uniprotkb:fz(gene name)|psi-mi:fz(display_short)|uniprotkb:CG17697(orf name)|uniprotkb:Frizzled-1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872942 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523502.1|ensemblmetazoa:FBgn0284084(gene)|ensemblmetazoa:FBtr0079432(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007398"(ectoderm development)|go:"GO:0007418"(ventral midline development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007523"(larval visceral muscle development)|go:"GO:0007616"(long-term memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014019"(neuroblast development)|go:"GO:0016015"(morphogen activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0061328"(posterior Malpighian tubule development)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061332"(Malpighian tubule bud morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR043158|reactome:R-DME-201681|reactome:R-DME-209387|reactome:R-DME-209440|reactome:R-DME-209472|reactome:R-DME-3238698|reactome:R-DME-4086400|reactome:R-DME-4641262|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032876"(negative regulation of DNA endoreduplication)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035217"(labial disc development)|go:"GO:0035220"(wing disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035263"(genital disc sexually dimorphic development)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035311"(wing cell fate specification)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043195"(terminal bouton)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048332"(mesoderm morphogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048728"(proboscis development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050808"(synapse organization)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0060061"(Spemann organizer formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060914"(heart formation)|go:"GO:0061316"(canonical Wnt signaling pathway involved in heart development)|go:"GO:0045572"(positive regulation of imaginal disc growth)|flybase:FBgn0284084|dip:DIP-21777N refseq:NP_524812.1|flybase:FBgn0001085|dip:DIP-22727N|ensemblmetazoa:FBgn0001085(gene)|ensemblmetazoa:FBtr0075743(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0007494"(midgut development)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035320"(imaginal disc-derived wing hair site selection)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0042685"(cardioblast cell fate specification)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048675"(axon extension)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026552|interpro:IPR036790|reactome:R-DME-209387|reactome:R-DME-209440|reactome:R-DME-209472|reactome:R-DME-350368|reactome:R-DME-350376|reactome:R-DME-350379|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086398|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641262|reactome:R-DME-5140745 pubmed:10556068(see-also)|pubmed:11437451(see-also)|pubmed:12205098(see-also)|pubmed:10457026(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ioGPXpHjZchgMT2/PR2ivC4Jo+s7227 rogid:4tfZSq+RV6xKUPYq7P2V6Nkvzxs7227 intact-crc:A6979C7E20539D0B|rigid:54Exs/l4ujUfW0R2RtYZmlCPRNc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P28465 uniprotkb:Q9VVX3 intact:EBI-869633|uniprotkb:Q86PC8|uniprotkb:Q9V584|ensemblmetazoa:FBpp0087596 intact:EBI-118222|uniprotkb:A8JNV7|uniprotkb:Q494J1|uniprotkb:Q94916|uniprotkb:Q9VVX2|intact:EBI-3433048|ensemblmetazoa:FBpp0074795|ensemblmetazoa:FBpp0074796|ensemblmetazoa:FBpp0111803|ensemblmetazoa:FBpp0288861|ensemblmetazoa:FBpp0303227|ensemblmetazoa:FBpp0304981 psi-mi:wnt2_drome(display_long)|uniprotkb:dWnt-2(gene name synonym)|uniprotkb:Wnt2(gene name)|psi-mi:Wnt2(display_short)|uniprotkb:Wnt-2(gene name synonym)|uniprotkb:CG1916(orf name) psi-mi:friz2_drome(display_long)|uniprotkb:CG9739(orf name)|uniprotkb:fz2(gene name)|psi-mi:fz2(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872946 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476810.1|flybase:FBgn0004360|ensemblmetazoa:FBgn0004360(gene)|ensemblmetazoa:FBtr0088512(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048675"(axon extension)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR043158|reactome:R-DME-3238698 refseq:NP_001262036.1|refseq:NP_001262038.1|refseq:NP_001097643.1|refseq:NP_001137971.1|refseq:NP_524155.1|refseq:NP_730389.1|flybase:FBgn0016797|ensemblmetazoa:FBgn0016797(gene)|ensemblmetazoa:FBtr0075028(transcript)|ensemblmetazoa:FBtr0075029(transcript)|ensemblmetazoa:FBtr0112890(transcript)|ensemblmetazoa:FBtr0299586(transcript)|ensemblmetazoa:FBtr0330194(transcript)|ensemblmetazoa:FBtr0332735(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0042685"(cardioblast cell fate specification)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048675"(axon extension)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|reactome:R-DME-209387|reactome:R-DME-209440|reactome:R-DME-209472|reactome:R-DME-4086398|reactome:R-DME-4608870|reactome:R-DME-5140745|dip:DIP-17196N pubmed:12205098(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:4bsdFt58cDSXk5mgtety27IEE2E7227 rogid:DONCeTs13fWZaew7Mv060K0qqjg7227 intact-crc:40E98AE5F866DB41|rigid:D344FpzPksD+PLboA9RfNL+4elY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09615 uniprotkb:Q9VVX3 intact:EBI-98242|uniprotkb:Q27768|uniprotkb:Q27769|uniprotkb:Q8IPI1|uniprotkb:Q8MQP9|uniprotkb:Q9VM27|ensemblmetazoa:FBpp0079060 intact:EBI-118222|uniprotkb:A8JNV7|uniprotkb:Q494J1|uniprotkb:Q94916|uniprotkb:Q9VVX2|intact:EBI-3433048|ensemblmetazoa:FBpp0074795|ensemblmetazoa:FBpp0074796|ensemblmetazoa:FBpp0111803|ensemblmetazoa:FBpp0288861|ensemblmetazoa:FBpp0303227|ensemblmetazoa:FBpp0304981 psi-mi:wntg_drome(display_long)|uniprotkb:Protein Wnt-1(gene name synonym)|uniprotkb:Protein int-1(gene name synonym)|uniprotkb:CG4889(orf name)|uniprotkb:wg(gene name)|psi-mi:wg(display_short)|uniprotkb:dWnt-1(gene name synonym)|uniprotkb:dInt-1(gene name synonym) psi-mi:friz2_drome(display_long)|uniprotkb:CG9739(orf name)|uniprotkb:fz2(gene name)|psi-mi:fz2(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872950 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523502.1|ensemblmetazoa:FBgn0284084(gene)|ensemblmetazoa:FBtr0079432(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007398"(ectoderm development)|go:"GO:0007418"(ventral midline development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007523"(larval visceral muscle development)|go:"GO:0007616"(long-term memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014019"(neuroblast development)|go:"GO:0016015"(morphogen activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0061328"(posterior Malpighian tubule development)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061332"(Malpighian tubule bud morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR043158|reactome:R-DME-201681|reactome:R-DME-209387|reactome:R-DME-209440|reactome:R-DME-209472|reactome:R-DME-3238698|reactome:R-DME-4086400|reactome:R-DME-4641262|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032876"(negative regulation of DNA endoreduplication)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035217"(labial disc development)|go:"GO:0035220"(wing disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035263"(genital disc sexually dimorphic development)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035311"(wing cell fate specification)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043195"(terminal bouton)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048332"(mesoderm morphogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048728"(proboscis development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050808"(synapse organization)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0060061"(Spemann organizer formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060914"(heart formation)|go:"GO:0061316"(canonical Wnt signaling pathway involved in heart development)|go:"GO:0045572"(positive regulation of imaginal disc growth)|flybase:FBgn0284084|dip:DIP-21777N refseq:NP_001262036.1|refseq:NP_001262038.1|refseq:NP_001097643.1|refseq:NP_001137971.1|refseq:NP_524155.1|refseq:NP_730389.1|flybase:FBgn0016797|ensemblmetazoa:FBgn0016797(gene)|ensemblmetazoa:FBtr0075028(transcript)|ensemblmetazoa:FBtr0075029(transcript)|ensemblmetazoa:FBtr0112890(transcript)|ensemblmetazoa:FBtr0299586(transcript)|ensemblmetazoa:FBtr0330194(transcript)|ensemblmetazoa:FBtr0332735(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0042685"(cardioblast cell fate specification)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048675"(axon extension)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|reactome:R-DME-209387|reactome:R-DME-209440|reactome:R-DME-209472|reactome:R-DME-4086398|reactome:R-DME-4608870|reactome:R-DME-5140745|dip:DIP-17196N pubmed:9630221(see-also)|pubmed:9671581(see-also)|pubmed:9822716(see-also)|pubmed:9875855(see-also)|pubmed:9875856(see-also)|pubmed:9876186(see-also)|pubmed:10421372(see-also)|pubmed:11437451(see-also)|pubmed:8717036(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ioGPXpHjZchgMT2/PR2ivC4Jo+s7227 rogid:DONCeTs13fWZaew7Mv060K0qqjg7227 intact-crc:BA2F991F90741640|rigid:6EX0rOr0Uz1TEs6hgFywKenc1LY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P28465 uniprotkb:O77438 intact:EBI-869633|uniprotkb:Q86PC8|uniprotkb:Q9V584|ensemblmetazoa:FBpp0087596 intact:EBI-97795|uniprotkb:Q540W1|uniprotkb:Q9I7Z7|uniprotkb:Q9NIU0|uniprotkb:Q9U902|uniprotkb:Q9W5D5 psi-mi:wnt2_drome(display_long)|uniprotkb:dWnt-2(gene name synonym)|uniprotkb:Wnt2(gene name)|psi-mi:Wnt2(display_short)|uniprotkb:Wnt-2(gene name synonym)|uniprotkb:CG1916(orf name) psi-mi:friz3_drome(display_long)|uniprotkb:fz3(gene name)|psi-mi:fz3(display_short)|uniprotkb:CG16785(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872954 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476810.1|flybase:FBgn0004360|ensemblmetazoa:FBgn0004360(gene)|ensemblmetazoa:FBtr0088512(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048675"(axon extension)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR043158|reactome:R-DME-3238698 refseq:NP_001284760.1|refseq:NP_525035.2|flybase:FBgn0027343|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|reactome:R-DME-4086398|reactome:R-DME-4608870|reactome:R-DME-5099900|reactome:R-DME-8856825|reactome:R-DME-8856828 pubmed:12205098(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:4bsdFt58cDSXk5mgtety27IEE2E7227 rogid:+qou9Aq655ywnMRMga7YlUXx2/s7227 intact-crc:56F42F040D7F7643|rigid:zMZyoofbu4NFCSrj3PjkZnOPojo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09615 uniprotkb:O77438 intact:EBI-98242|uniprotkb:Q27768|uniprotkb:Q27769|uniprotkb:Q8IPI1|uniprotkb:Q8MQP9|uniprotkb:Q9VM27|ensemblmetazoa:FBpp0079060 intact:EBI-97795|uniprotkb:Q540W1|uniprotkb:Q9I7Z7|uniprotkb:Q9NIU0|uniprotkb:Q9U902|uniprotkb:Q9W5D5 psi-mi:wntg_drome(display_long)|uniprotkb:Protein Wnt-1(gene name synonym)|uniprotkb:Protein int-1(gene name synonym)|uniprotkb:CG4889(orf name)|uniprotkb:wg(gene name)|psi-mi:wg(display_short)|uniprotkb:dWnt-1(gene name synonym)|uniprotkb:dInt-1(gene name synonym) psi-mi:friz3_drome(display_long)|uniprotkb:fz3(gene name)|psi-mi:fz3(display_short)|uniprotkb:CG16785(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872958 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523502.1|ensemblmetazoa:FBgn0284084(gene)|ensemblmetazoa:FBtr0079432(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007398"(ectoderm development)|go:"GO:0007418"(ventral midline development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007523"(larval visceral muscle development)|go:"GO:0007616"(long-term memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014019"(neuroblast development)|go:"GO:0016015"(morphogen activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0061328"(posterior Malpighian tubule development)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061332"(Malpighian tubule bud morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR043158|reactome:R-DME-201681|reactome:R-DME-209387|reactome:R-DME-209440|reactome:R-DME-209472|reactome:R-DME-3238698|reactome:R-DME-4086400|reactome:R-DME-4641262|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032876"(negative regulation of DNA endoreduplication)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035217"(labial disc development)|go:"GO:0035220"(wing disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035263"(genital disc sexually dimorphic development)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035311"(wing cell fate specification)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043195"(terminal bouton)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048332"(mesoderm morphogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048728"(proboscis development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050808"(synapse organization)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0060061"(Spemann organizer formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060914"(heart formation)|go:"GO:0061316"(canonical Wnt signaling pathway involved in heart development)|go:"GO:0045572"(positive regulation of imaginal disc growth)|flybase:FBgn0284084|dip:DIP-21777N refseq:NP_001284760.1|refseq:NP_525035.2|flybase:FBgn0027343|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR036790|reactome:R-DME-4086398|reactome:R-DME-4608870|reactome:R-DME-5099900|reactome:R-DME-8856825|reactome:R-DME-8856828 pubmed:12205098(see-also)|pubmed:10498678(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ioGPXpHjZchgMT2/PR2ivC4Jo+s7227 rogid:+qou9Aq655ywnMRMga7YlUXx2/s7227 intact-crc:FCA68DC8941D15FA|rigid:H2flKhZdXg29XPJn2e4yz9YHHkU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VFX1 uniprotkb:Q9NBW1 intact:EBI-187543|ensemblmetazoa:FBpp0082243 intact:EBI-100535|ensemblmetazoa:FBpp0070976|ensemblmetazoa:FBpp0070977|uniprotkb:Q9W3S2 psi-mi:wnt8_drome(display_long)|uniprotkb:wntD(gene name)|psi-mi:wntD(display_short)|uniprotkb:CG8458(orf name)|uniprotkb:Wnt8(gene name synonym)|uniprotkb:Protein Wnt-8(gene name synonym)|uniprotkb:dWnt-8(gene name synonym) psi-mi:friz4_drome(display_long)|uniprotkb:fz4(gene name)|psi-mi:fz4(display_short)|uniprotkb:CG4626(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872962 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_650272.1|flybase:FBgn0038134|ensemblmetazoa:FBgn0038134(gene)|ensemblmetazoa:FBtr0082775(transcript)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007280"(pole cell migration)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR026540|interpro:IPR043158|rcsb pdb:4KRR|reactome:R-DME-3238698|reactome:R-DME-4086398|reactome:R-DME-4086400 ensemblmetazoa:FBgn0027342(gene)|ensemblmetazoa:FBtr0071017(transcript)|ensemblmetazoa:FBtr0071018(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026551|interpro:IPR036790|interpro:IPR041765|reactome:R-DME-4086398|reactome:R-DME-4608870|reactome:R-DME-5099900|reactome:R-DME-8856825|reactome:R-DME-8856828|refseq:NP_511068.2|refseq:NP_727170.2|flybase:FBgn0027342 pubmed:12205098(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:1t6IW8DsvSHtkYaK1noZcr6DkVg7227 rogid:X48Mehp+PvS4seoRrz4YPQO61IU7227 intact-crc:A28B80BC6CD5C73F|rigid:oILHOIruoyGssRyfmlTQIcfOPv0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9XYP8 uniprotkb:P23257 intact:EBI-176976|uniprotkb:Q9VY94|ensemblmetazoa:FBpp0073672 intact:EBI-178952|uniprotkb:Q9VQJ5|ensemblmetazoa:FBpp0077326 psi-mi:gcp3_drome(display_long)|uniprotkb:Grip91(gene name)|psi-mi:Grip91(display_short)|uniprotkb:Gamma-ring complex protein 91 kDa(gene name synonym)|uniprotkb:"l(1)dd4"(gene name synonym)|uniprotkb:CG10988(orf name) psi-mi:tbg1_drome(display_long)|uniprotkb:gammaTub23C(gene name)|psi-mi:gammaTub23C(display_short)|uniprotkb:Tub23C(gene name synonym)|uniprotkb:TubG(gene name synonym)|uniprotkb:TubG1(gene name synonym)|uniprotkb:CG3157(orf name)|uniprotkb:TubG23C(gene name synonym)|uniprotkb:Gamma-1-tubulin(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872966 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524919.2|flybase:FBgn0001612|dip:DIP-19100N|ensemblmetazoa:FBgn0001612(gene)|ensemblmetazoa:FBtr0073841(transcript)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470 refseq:NP_476804.1|flybase:FBgn0260639|ensemblmetazoa:FBgn0260639(gene)|ensemblmetazoa:FBtr0077641(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0019001"(guanyl nucleotide binding)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000217(Tubulin)|interpro:IPR002454(Gamma tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103 pubmed:11134079(see-also)|pubmed:10037793(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:K2mGj8qJLEn11hLmlwxkQr1cVYM7227 rogid:v8VA+z+B2QYczBYdLotcT1Rptso7227 intact-crc:15B3213CF52C1DD8|rigid:xNp90h3ZSCjt/69o2EbNI7FAhjg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9XYP7 uniprotkb:P23257 intact:EBI-252093|uniprotkb:Q95RT7|ensemblmetazoa:FBpp0074545 intact:EBI-178952|uniprotkb:Q9VQJ5|ensemblmetazoa:FBpp0077326 psi-mi:gcp2_drome(display_long)|uniprotkb:Grip84(gene name)|psi-mi:Grip84(display_short)|uniprotkb:CG3917(orf name)|uniprotkb:Gamma-ring complex protein 84 kDa(gene name synonym) psi-mi:tbg1_drome(display_long)|uniprotkb:gammaTub23C(gene name)|psi-mi:gammaTub23C(display_short)|uniprotkb:Tub23C(gene name synonym)|uniprotkb:TubG(gene name synonym)|uniprotkb:TubG1(gene name synonym)|uniprotkb:CG3157(orf name)|uniprotkb:TubG23C(gene name synonym)|uniprotkb:Gamma-1-tubulin(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872970 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523409.1|refseq:NP_728265.1|flybase:FBgn0026430|refseq:NP_001285444.1|ensemblmetazoa:FBgn0026430(gene)|ensemblmetazoa:FBtr0074776(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470 refseq:NP_476804.1|flybase:FBgn0260639|ensemblmetazoa:FBgn0260639(gene)|ensemblmetazoa:FBtr0077641(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0019001"(guanyl nucleotide binding)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000217(Tubulin)|interpro:IPR002454(Gamma tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103 pubmed:11134079(see-also)|pubmed:10037793(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KP3ZSIRYgfIRfWsvpQPMvSU1tOM7227 rogid:v8VA+z+B2QYczBYdLotcT1Rptso7227 intact-crc:D94C213C6EF75F91|rigid:cKWo+Rfv47jEzROiKYiFNptTc9k false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P13706 uniprotkb:P07486 intact:EBI-235735|uniprotkb:Q27590|uniprotkb:Q27925|uniprotkb:Q95077|uniprotkb:Q95TV4|uniprotkb:Q9VML0 intact:EBI-119077|uniprotkb:A5XCT3|uniprotkb:A5XCT7|uniprotkb:A4UZ75|uniprotkb:Q8SXG8|uniprotkb:Q9V318|ensemblmetazoa:FBpp0087977|ensemblmetazoa:FBpp0099914 psi-mi:gpda_drome(display_long)|uniprotkb:Gpdh(gene name synonym)|uniprotkb:CG9042(orf name)|uniprotkb:Gpdh1(gene name)|psi-mi:Gpdh1(display_short) psi-mi:g3p1_drome(display_long)|uniprotkb:Gapdh1(gene name)|psi-mi:Gapdh1(display_short)|uniprotkb:CG12055(orf name)|uniprotkb:Gadph-1(gene name synonym)|uniprotkb:Glyceraldehyde-3-phosphate dehydrogenase I(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872974 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476565.1|refseq:NP_476566.1|refseq:NP_476567.1|flybase:FBgn0001128|refseq:NP_001260111.1|refseq:NP_001260112.1|refseq:NP_001260113.1|dip:DIP-21689N|go:"GO:0004367"(glycerol-3-phosphate dehydrogenase [NAD+] activity)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006067"(ethanol metabolic process)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006116"(NADH oxidation)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006650"(glycerophospholipid metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0007629"(flight behavior)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046168"(glycerol-3-phosphate catabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0055093"(response to hyperoxia)|interpro:IPR006109(NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal)|interpro:IPR006168(NAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR011128(NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR017751(NAD-dependent glycerol-3-phosphate dehydrogenase, eukaryotic)|interpro:IPR036291|reactome:R-DME-1483166 refseq:NP_001033936.1|refseq:NP_525108.2|flybase:FBgn0001091|ensemblmetazoa:FBgn0001091(gene)|ensemblmetazoa:FBtr0088903(transcript)|ensemblmetazoa:FBtr0100479(transcript)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|reactome:R-DME-70171|reactome:R-DME-70263 pubmed:12756285(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:76a690NsDWc75jfcpNavsh0gFW87227 rogid:SWo7G67sD+c5P6vzKjHSlrO/ILE7227 intact-crc:62388D3A5E63C234|rigid:XVMMZYo/Q33b+XlryJhhk0E1gN0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24326 uniprotkb:P27091 intact:EBI-869183 intact:EBI-184929|uniprotkb:Q9W1I4|ensemblmetazoa:FBpp0072036|ensemblmetazoa:FBpp0309939 psi-mi:q24326_drome(display_long)|uniprotkb:tkv(gene name)|psi-mi:tkv(display_short)|uniprotkb:dtfr(gene name synonym)|uniprotkb:CG14026(orf name) psi-mi:60a_drome(display_long)|uniprotkb:gbb(gene name)|psi-mi:gbb(display_short)|uniprotkb:60A(gene name synonym)|uniprotkb:TGFb-60A(gene name synonym)|uniprotkb:CG5562(orf name)|uniprotkb:Protein glass bottom boat(gene name synonym)|uniprotkb:gbb-60A(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872978 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0003716|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005025"(transforming growth factor beta receptor activity, type I)|go:"GO:0005524"(ATP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007391"(dorsal closure)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008354"(germ cell migration)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030721"(spectrosome organization)|go:"GO:0035215"(genital disc development)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0043235"(receptor complex)|go:"GO:0045202"(synapse)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0046332"(SMAD binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0060799"(transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification)|go:"GO:0061327"(anterior Malpighian tubule development)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|interpro:IPR000333(Activin type II receptor)|interpro:IPR000472(TGF-beta receptor/activin receptor, type I/II)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003605(TGF beta receptor, GS motif)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) refseq:NP_477340.1|flybase:FBgn0024234|refseq:NP_001286786.1|dip:DIP-19466N|ensemblmetazoa:FBgn0024234(gene)|ensemblmetazoa:FBtr0072127(transcript)|ensemblmetazoa:FBtr0343274(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007391"(dorsal closure)|go:"GO:0007419"(ventral cord development)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007504"(larval fat body development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0012505"(endomembrane system)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031045"(dense core granule)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0045202"(synapse)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048636"(positive regulation of muscle organ development)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0098917"(retrograde trans-synaptic signaling)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001111("Transforming growth factor beta (TGFb), N-terminal")|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR017948|interpro:IPR029034|reactome:R-DME-114608|reactome:R-DME-2129379|reactome:R-DME-2173789|reactome:R-DME-2173791|reactome:R-DME-3000170|reactome:R-DME-381426|reactome:R-DME-8941855|reactome:R-DME-8941858|reactome:R-DME-8951936|reactome:R-DME-8957275 pubmed:9735359(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:FB2IWkOHoz7sCHdulTN4juLDwhk7227 rogid:Z3NX1qbSBiRBBJPKNgiZseJPPGk7227 intact-crc:03B2F8EAB8A83268|rigid:cOuYGDcrn+ryCfvkuc3o7k9L0yg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O76522 uniprotkb:Q01820 intact:EBI-499003 intact:EBI-176400|uniprotkb:Q9V4X5|ensemblmetazoa:FBpp0087789 psi-mi:o76522_drome(display_long)|uniprotkb:CG9423(orf name)|uniprotkb:Kap-alpha3(gene name)|psi-mi:Kap-alpha3(display_short)|uniprotkb:Kap-alpha-3(gene name synonym) psi-mi:gcl_drome(display_long)|uniprotkb:gcl(gene name)|psi-mi:gcl(display_short)|uniprotkb:CG8411(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872982 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0027338|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0009411"(response to UV)|go:"GO:0017022"(myosin binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975 refseq:NP_724708.1|flybase:FBgn0005695|dip:DIP-21769N|go:"GO:0005643"(nuclear pore)|go:"GO:0005938"(cell cortex)|go:"GO:0007278"(pole cell fate determination)|go:"GO:0007279"(pole cell formation)|go:"GO:0007281"(germ cell development)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0120177"(negative regulation of torso signaling pathway)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR043380|ensemblmetazoa:FBgn0005695(gene)|ensemblmetazoa:FBtr0088710(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope) pubmed:10614818(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Ry3o76SK18N9E4hRVDYUCOJl6U07227 rogid:juMykH/lgZ3hnV4gWjnvhEp4jUE7227 intact-crc:60F2B3C8757FBEE3|rigid:ORccnpf1j7sEXdFgVKAac/y1sEg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P05049 uniprotkb:O62589 intact:EBI-82507|uniprotkb:Q29QH0|uniprotkb:Q9VFZ7|ensemblmetazoa:FBpp0082184|ensemblmetazoa:FBpp0111746 intact:EBI-115952|ensemblmetazoa:FBpp0304588|uniprotkb:D9PTR2|uniprotkb:M9PEE0|uniprotkb:M9PGY7|uniprotkb:M9PJK1|uniprotkb:Q1EC38 psi-mi:snak_drome(display_long)|uniprotkb:snk(gene name)|psi-mi:snk(display_short)|uniprotkb:CG7996(orf name) psi-mi:gd_drome(display_long)|uniprotkb:gd(gene name)|psi-mi:gd(display_short)|uniprotkb:CG1505(orf name)|uniprotkb:Protein gastrulation defective(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872986 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097766.1|refseq:NP_524338.2|flybase:FBgn0003450|ensemblmetazoa:FBgn0003450(gene)|ensemblmetazoa:FBtr0082716(transcript)|ensemblmetazoa:FBtr0112833(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0031638"(zymogen activation)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR022700|interpro:IPR033116|interpro:IPR043504|reactome:R-DME-209442 flybase:FBgn0000808|ensemblmetazoa:FBgn0000808(gene)|ensemblmetazoa:FBtr0332309(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031638"(zymogen activation)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0098595"(perivitelline space)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR031986|interpro:IPR043504|reactome:R-DME-209442|refseq:NP_001303552.1|refseq:NP_001259478.1|refseq:NP_001259479.1|refseq:NP_001259480.1 pubmed:11350927(see-also)|pubmed:11296245(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:p90dDWv07u/IMHJwjtSeNT5pwuE7227 rogid:7JiWN5uFENDvUOzB+akqxyqYmRM7227 intact-crc:3D556020940450C4|rigid:CMml6lwRWqlAOQafEYlmFwVliss false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O62589 uniprotkb:O62589 intact:EBI-115952|ensemblmetazoa:FBpp0304588|uniprotkb:D9PTR2|uniprotkb:M9PEE0|uniprotkb:M9PGY7|uniprotkb:M9PJK1|uniprotkb:Q1EC38 intact:EBI-115952|ensemblmetazoa:FBpp0304588|uniprotkb:D9PTR2|uniprotkb:M9PEE0|uniprotkb:M9PGY7|uniprotkb:M9PJK1|uniprotkb:Q1EC38 psi-mi:gd_drome(display_long)|uniprotkb:gd(gene name)|psi-mi:gd(display_short)|uniprotkb:CG1505(orf name)|uniprotkb:Protein gastrulation defective(gene name synonym) psi-mi:gd_drome(display_long)|uniprotkb:gd(gene name)|psi-mi:gd(display_short)|uniprotkb:CG1505(orf name)|uniprotkb:Protein gastrulation defective(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872990 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0000808|ensemblmetazoa:FBgn0000808(gene)|ensemblmetazoa:FBtr0332309(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031638"(zymogen activation)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0098595"(perivitelline space)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR031986|interpro:IPR043504|reactome:R-DME-209442|refseq:NP_001303552.1|refseq:NP_001259478.1|refseq:NP_001259479.1|refseq:NP_001259480.1 flybase:FBgn0000808|ensemblmetazoa:FBgn0000808(gene)|ensemblmetazoa:FBtr0332309(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0031638"(zymogen activation)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0098595"(perivitelline space)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR031986|interpro:IPR043504|reactome:R-DME-209442|refseq:NP_001303552.1|refseq:NP_001259478.1|refseq:NP_001259479.1|refseq:NP_001259480.1 pubmed:11350927(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:7JiWN5uFENDvUOzB+akqxyqYmRM7227 rogid:7JiWN5uFENDvUOzB+akqxyqYmRM7227 intact-crc:1E95BB2C2F698030|rigid:IbxIFNfQXa79pWt0giBuDMu7AbI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9NFR7 uniprotkb:P20353 intact:EBI-497189 intact:EBI-119189|uniprotkb:Q9VS04|ensemblmetazoa:FBpp0076643 psi-mi:q9nfr7_drome(display_long)|uniprotkb:pins(gene name)|psi-mi:pins(display_short)|uniprotkb:raps(gene name synonym)|uniprotkb:CG5692(orf name) psi-mi:gnai_drome(display_long)|uniprotkb:Galphai(gene name)|psi-mi:Galphai(display_short)|uniprotkb:G-OA65C(gene name synonym)|uniprotkb:G-ialpha65A(gene name synonym)|uniprotkb:"Guanine nucleotide-binding protein G(i) subunit alpha 65A"(gene name synonym)|uniprotkb:CG10060(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872994 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0040080|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0055059"(asymmetric neuroblast division)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 refseq:NP_477502.1|flybase:FBgn0001104|ensemblmetazoa:FBgn0001104(gene)|ensemblmetazoa:FBtr0076934(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007419"(ventral cord development)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032291"(axon ensheathment in central nervous system)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045179"(apical cortex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0060857"(establishment of glial blood-brain barrier)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-DME-170670|reactome:R-DME-392170|reactome:R-DME-400042|reactome:R-DME-418594|reactome:R-DME-9009391|dip:DIP-17262N pubmed:12024035(see-also)|pubmed:10875939(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:bJLhIKptzMvBzyui3OKrX5Ey3sw7227 rogid:8aWPqFXD0lfIYSuPXAYso82oNRo7227 intact-crc:90259CECC5A95EFF|rigid:NuF8GWG9K12bsmECX8XGKFcw3kA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9U9A9 uniprotkb:Q7K0T0 intact:EBI-869664 intact:EBI-869652|ensemblmetazoa:FBpp0074588 psi-mi:q9u9a9_drome(display_long)|uniprotkb:Tsc1(gene name)|psi-mi:Tsc1(display_short)|uniprotkb:TSC1(gene name synonym)|uniprotkb:CG6147(orf name) psi-mi:q7k0t0_drome(display_long)|uniprotkb:gig(gene name)|psi-mi:gig(display_short)|uniprotkb:CG6975(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872998 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0026317|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0035069"(larval midgut histolysis)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048640"(negative regulation of developmental growth)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1902350"(cellular response to chloroquine)|go:"GO:2000331"(regulation of terminal button organization)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR007483(Hamartin)|reactome:R-DME-110523 flybase:FBgn0005198|ensemblmetazoa:FBgn0005198(gene)|ensemblmetazoa:FBtr0074819(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0035069"(larval midgut histolysis)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1902350"(cellular response to chloroquine)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018515|interpro:IPR024584|interpro:IPR027107|interpro:IPR035974 pubmed:11390358(see-also)|pubmed:11348592(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:bv7PpQf7s0sY4UtOd9v6b9g6tEs7227 rogid:hKVOJrKISwkA0tMHB8HVei0PCK07227 intact-crc:F4E59173B0FBB603|rigid:+dyEoxpSqxbddIOlAhg2ywmBxP4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O46308 uniprotkb:Q9VUI0 intact:EBI-137864|ensemblmetazoa:FBpp0070225 intact:EBI-174199|ensemblmetazoa:FBpp0075447 psi-mi:o46308_drome(display_long)|uniprotkb:png(gene name)|psi-mi:png(display_short)|uniprotkb:"EG:8D8.5"(gene name synonym)|uniprotkb:Dmel\CG11420(gene name synonym)|uniprotkb:PNG(gene name synonym)|uniprotkb:Png(gene name synonym)|uniprotkb:"fs(1)M2"(gene name synonym)|uniprotkb:pan-gnu(gene name synonym)|uniprotkb:Dmel_CG11420(orf name)|uniprotkb:"fs(1)N"(gene name synonym)|uniprotkb:CG11420(orf name) psi-mi:q9vui0_drome(display_long)|uniprotkb:gnu(gene name)|psi-mi:gnu(display_short)|uniprotkb:Dmel\CG5272(gene name synonym)|uniprotkb:Gnu(gene name synonym)|uniprotkb:Dmel_CG5272(orf name)|uniprotkb:CG5272(orf name)|uniprotkb:GNU(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873002 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477492.1|flybase:FBgn0000826|dip:DIP-19818N|ensemblmetazoa:FBgn0000826(gene)|ensemblmetazoa:FBtr0070234(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007343"(egg activation)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1902911"(protein kinase complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like) refseq:NP_648726.1|flybase:FBgn0001120|ensemblmetazoa:FBgn0001120(gene)|ensemblmetazoa:FBtr0075697(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0007343"(egg activation)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1902911"(protein kinase complex)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type) pubmed:14665672(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:edS/8LZU3aJj4+A1YmKxmD5wQY87227 rogid:WNZ3fQXG/g5GYaaCt4xLPkQUXcs7227 intact-crc:A84B4234D908AC6E|rigid:UjOvGPXUHcEF1Rz6+mnxPGGhLag false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24450 uniprotkb:P13706 intact:EBI-869684 intact:EBI-235735|uniprotkb:Q27590|uniprotkb:Q27925|uniprotkb:Q95077|uniprotkb:Q95TV4|uniprotkb:Q9VML0 psi-mi:q24450_drome(display_long)|uniprotkb:Pglym78(gene name)|psi-mi:Pglym78(display_short)|uniprotkb:CG1721(orf name) psi-mi:gpda_drome(display_long)|uniprotkb:Gpdh(gene name synonym)|uniprotkb:CG9042(orf name)|uniprotkb:Gpdh1(gene name)|psi-mi:Gpdh1(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873006 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0014869|go:"GO:0003824"(catalytic activity)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033 refseq:NP_476565.1|refseq:NP_476566.1|refseq:NP_476567.1|flybase:FBgn0001128|refseq:NP_001260111.1|refseq:NP_001260112.1|refseq:NP_001260113.1|dip:DIP-21689N|go:"GO:0004367"(glycerol-3-phosphate dehydrogenase [NAD+] activity)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006067"(ethanol metabolic process)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006116"(NADH oxidation)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006650"(glycerophospholipid metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0007629"(flight behavior)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046168"(glycerol-3-phosphate catabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0055093"(response to hyperoxia)|interpro:IPR006109(NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal)|interpro:IPR006168(NAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR011128(NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR017751(NAD-dependent glycerol-3-phosphate dehydrogenase, eukaryotic)|interpro:IPR036291|reactome:R-DME-1483166 pubmed:12756285(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8bAZbWPl6wpWNMAzWRSj3YBJoaQ7227 rogid:76a690NsDWc75jfcpNavsh0gFW87227 intact-crc:2F6F3649C3B3A7EB|rigid:8lbnzb368ZR8Smf9Ha2INcAJjMQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24325 uniprotkb:P13002 intact:EBI-141415|ensemblmetazoa:FBpp0076090|ensemblmetazoa:FBpp0304934|uniprotkb:Q8SZR7|uniprotkb:Q9VT64|intact:EBI-1631628 intact:EBI-497032|uniprotkb:A0JQ61|uniprotkb:Q6NN37|uniprotkb:Q86PE1|uniprotkb:Q8MMA8|uniprotkb:Q8MMB0|uniprotkb:Q8MMB1|uniprotkb:Q960H2|uniprotkb:Q9TYG4|uniprotkb:Q9V889|uniprotkb:Q9V890|uniprotkb:Q9V891|uniprotkb:A1ZB05|ensemblmetazoa:FBpp0288984 psi-mi:taf2_drome(display_long)|uniprotkb:Taf2(gene name)|psi-mi:Taf2(display_short)|uniprotkb:TAF150(gene name synonym)|uniprotkb:CG6711(orf name)|uniprotkb:Transcription initiation factor TFIID 150 kDa subunit(gene name synonym) psi-mi:elf1_drome(display_long)|uniprotkb:Protein grainy-head(gene name synonym)|uniprotkb:DNA-binding protein ELF-1(gene name synonym)|uniprotkb:Element I-binding activity(gene name synonym)|uniprotkb:Transcription factor NTF-1(gene name synonym)|uniprotkb:grh(gene name)|psi-mi:grh(display_short)|uniprotkb:elf1(gene name synonym)|uniprotkb:CG5058(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873010 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-73779|ensemblmetazoa:FBgn0011836(gene)|ensemblmetazoa:FBtr0076361(transcript)|ensemblmetazoa:FBtr0332688(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR037813|interpro:IPR042097|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|refseq:NP_729571.1|flybase:FBgn0011836|refseq:NP_001261668.1|dip:DIP-255N refseq:NP_001286551.1|refseq:NP_476842.2|refseq:NP_476843.2|refseq:NP_476844.2|refseq:NP_476845.2|refseq:NP_725725.1|flybase:FBgn0259211|refseq:NP_725723.2|dip:DIP-59591N|ensemblmetazoa:FBgn0259211(gene)|ensemblmetazoa:FBtr0299706(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007402"(ganglion mother cell fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0008362"(chitin-based embryonic cuticle biosynthetic process)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061024"(membrane organization)|go:"GO:0061041"(regulation of wound healing)|interpro:IPR007604(CP2 transcription factor) pubmed:7923382(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:X8spP5vvdSP/mRH+UROTaTVBt8I7227 rogid:gqr/UyLOAYSbe0+X8a8SsXGSZz87227 intact-crc:28197D4900D57329|rigid:dWk8HoXR3XWQTowLjYe8IyrISzI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VB08 uniprotkb:P13002 intact:EBI-145507|uniprotkb:O18380|ensemblmetazoa:FBpp0084614 intact:EBI-497032|uniprotkb:A0JQ61|uniprotkb:Q6NN37|uniprotkb:Q86PE1|uniprotkb:Q8MMA8|uniprotkb:Q8MMB0|uniprotkb:Q8MMB1|uniprotkb:Q960H2|uniprotkb:Q9TYG4|uniprotkb:Q9V889|uniprotkb:Q9V890|uniprotkb:Q9V891|uniprotkb:A1ZB05|ensemblmetazoa:FBpp0288984 psi-mi:ring1_drome(display_long)|uniprotkb:Sce(gene name)|psi-mi:Sce(display_short)|uniprotkb:CG5595(orf name)|uniprotkb:dRING1(gene name synonym)|uniprotkb:dRING protein(gene name synonym)|uniprotkb:Sex comb extra protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:elf1_drome(display_long)|uniprotkb:Protein grainy-head(gene name synonym)|uniprotkb:DNA-binding protein ELF-1(gene name synonym)|uniprotkb:Element I-binding activity(gene name synonym)|uniprotkb:Transcription factor NTF-1(gene name synonym)|uniprotkb:grh(gene name)|psi-mi:grh(display_short)|uniprotkb:elf1(gene name synonym)|uniprotkb:CG5058(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873014 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477509.1|flybase:FBgn0003330|ensemblmetazoa:FBgn0003330(gene)|ensemblmetazoa:FBtr0085245(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0006342"|go:"GO:0007275"(multicellular organism development)|go:"GO:0007419"(ventral cord development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045498"(sex comb development)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR043540|reactome:R-DME-3108214|reactome:R-DME-3899300|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724|reactome:R-DME-8953750|dip:DIP-21764N refseq:NP_001286551.1|refseq:NP_476842.2|refseq:NP_476843.2|refseq:NP_476844.2|refseq:NP_476845.2|refseq:NP_725725.1|flybase:FBgn0259211|refseq:NP_725723.2|dip:DIP-59591N|ensemblmetazoa:FBgn0259211(gene)|ensemblmetazoa:FBtr0299706(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007402"(ganglion mother cell fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0008362"(chitin-based embryonic cuticle biosynthetic process)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061024"(membrane organization)|go:"GO:0061041"(regulation of wound healing)|interpro:IPR007604(CP2 transcription factor) pubmed:11865070(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:k490ckiQQNYwnWuAIGCHp63L4BA7227 rogid:gqr/UyLOAYSbe0+X8a8SsXGSZz87227 intact-crc:9FB18BD1236724C1|rigid:jJzHDoAeOp4uNeV1/Xj2a8XSX18 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24306 uniprotkb:Q24570 intact:EBI-456419|uniprotkb:A4V1Z9|uniprotkb:Q0E8E4|uniprotkb:Q8MRM5|uniprotkb:Q9VUX5|uniprotkb:A9UN33|ensemblmetazoa:FBpp0075254|ensemblmetazoa:FBpp0075255|ensemblmetazoa:FBpp0075256|ensemblmetazoa:FBpp0305793|ensemblmetazoa:FBpp0305794|ensemblmetazoa:FBpp0305795 intact:EBI-167445|uniprotkb:Q9VVP6|ensemblmetazoa:FBpp0074896 psi-mi:diap1_drome(display_long)|uniprotkb:Diap1(gene name)|psi-mi:Diap1(display_short)|uniprotkb:Apoptosis 1 inhibitor(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase th(gene name synonym)|uniprotkb:Iap1(gene name synonym)|uniprotkb:Inhibitor of apoptosis 1(gene name synonym)|uniprotkb:Protein thread(gene name synonym)|uniprotkb:th(gene name synonym)|uniprotkb:CG12284(orf name)|uniprotkb:RING-type E3 ubiquitin transferase Diap1(gene name synonym) psi-mi:grim_drome(display_long)|uniprotkb:grim(gene name)|psi-mi:grim(display_short)|uniprotkb:CG4345(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873018 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524101.2|refseq:NP_730097.1|refseq:NP_730098.1|flybase:FBgn0260635|refseq:NP_001261916.1|refseq:NP_001261917.1|refseq:NP_001261918.1|go:"GO:0006915"(apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0022416"(chaeta development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0045116"(protein neddylation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|ensemblmetazoa:FBgn0260635(gene)|ensemblmetazoa:FBtr0075499(transcript)|ensemblmetazoa:FBtr0075500(transcript)|ensemblmetazoa:FBtr0075501(transcript)|ensemblmetazoa:FBtr0333617(transcript)|ensemblmetazoa:FBtr0333618(transcript)|ensemblmetazoa:FBtr0333619(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|mint:Q24306|rcsb pdb:1JD4|rcsb pdb:1JD5|rcsb pdb:1JD6|rcsb pdb:1Q4Q|rcsb pdb:1SDZ|rcsb pdb:1SE0|rcsb pdb:3SIP|rcsb pdb:3SIQ|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-3769402|reactome:R-DME-390150|reactome:R-DME-5675482|reactome:R-DME-8948747|reactome:R-DME-8948751 ensemblmetazoa:FBgn0015946(gene)|ensemblmetazoa:FBtr0075130(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010623"(programmed cell death involved in cell development)|go:"GO:0035006"(melanization defense response)|go:"GO:0035193"(larval central nervous system remodeling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|rcsb pdb:1JD5|rcsb pdb:1SE0|refseq:NP_524137.2|flybase:FBgn0015946|dip:DIP-20419N pubmed:11511363(see-also)|pubmed:10655220(see-also)|pubmed:9584170(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:loBQ//cKQ1NYhq3gnIKwRBn5vZg7227 rogid:WvnSy/Je28KP26OK/wqNrhitUsg7227 intact-crc:A3FDEA5A25870AD5|rigid:OpcWzkFSVMkHItiiObhAVwaghvk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24307 uniprotkb:Q24570 intact:EBI-112046|uniprotkb:A4UZI4|uniprotkb:Q24115|uniprotkb:Q24149|uniprotkb:Q24177|uniprotkb:Q960U3|uniprotkb:Q9V7G1|ensemblmetazoa:FBpp0086431|ensemblmetazoa:FBpp0086432 intact:EBI-167445|uniprotkb:Q9VVP6|ensemblmetazoa:FBpp0074896 psi-mi:diap2_drome(display_long)|uniprotkb:Diap2(gene name)|psi-mi:Diap2(display_short)|uniprotkb:Apoptosis 2 inhibitor(gene name synonym)|uniprotkb:DIHA(gene name synonym)|uniprotkb:IAP homolog A(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:Iap2(gene name synonym)|uniprotkb:Ilp(gene name synonym)|uniprotkb:Inhibitor of apoptosis 2(gene name synonym)|uniprotkb:CG8293(orf name) psi-mi:grim_drome(display_long)|uniprotkb:grim(gene name)|psi-mi:grim(display_short)|uniprotkb:CG4345(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873022 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477127.1|refseq:NP_788362.1|flybase:FBgn0015247|ensemblmetazoa:FBgn0015247(gene)|ensemblmetazoa:FBtr0087296(transcript)|ensemblmetazoa:FBtr0087297(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006964"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0022416"(chaeta development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-209447|reactome:R-DME-3769402|reactome:R-DME-5675482|reactome:R-DME-8948747|reactome:R-DME-8948751 ensemblmetazoa:FBgn0015946(gene)|ensemblmetazoa:FBtr0075130(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010623"(programmed cell death involved in cell development)|go:"GO:0035006"(melanization defense response)|go:"GO:0035193"(larval central nervous system remodeling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|rcsb pdb:1JD5|rcsb pdb:1SE0|refseq:NP_524137.2|flybase:FBgn0015946|dip:DIP-20419N pubmed:9584170(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:DV11DOWYIDsW1ADpZuGD9UtXpYM7227 rogid:WvnSy/Je28KP26OK/wqNrhitUsg7227 intact-crc:D3FD864789F71B85|rigid:V5Lsgrhk6SGyqrBvieGuB3P0fPk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9XYP8 uniprotkb:Q9XYP7 intact:EBI-176976|uniprotkb:Q9VY94|ensemblmetazoa:FBpp0073672 intact:EBI-252093|uniprotkb:Q95RT7|ensemblmetazoa:FBpp0074545 psi-mi:gcp3_drome(display_long)|uniprotkb:Grip91(gene name)|psi-mi:Grip91(display_short)|uniprotkb:Gamma-ring complex protein 91 kDa(gene name synonym)|uniprotkb:"l(1)dd4"(gene name synonym)|uniprotkb:CG10988(orf name) psi-mi:gcp2_drome(display_long)|uniprotkb:Grip84(gene name)|psi-mi:Grip84(display_short)|uniprotkb:CG3917(orf name)|uniprotkb:Gamma-ring complex protein 84 kDa(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873026 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524919.2|flybase:FBgn0001612|dip:DIP-19100N|ensemblmetazoa:FBgn0001612(gene)|ensemblmetazoa:FBtr0073841(transcript)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470 refseq:NP_523409.1|refseq:NP_728265.1|flybase:FBgn0026430|refseq:NP_001285444.1|ensemblmetazoa:FBgn0026430(gene)|ensemblmetazoa:FBtr0074776(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470 pubmed:11134079(see-also)|pubmed:10037793(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:K2mGj8qJLEn11hLmlwxkQr1cVYM7227 rogid:KP3ZSIRYgfIRfWsvpQPMvSU1tOM7227 intact-crc:50FB7D87E92D56E0|rigid:Ho6jb5hCLWybX+rVQwPhPRYzYqs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42519 uniprotkb:P42287 intact:EBI-184916|uniprotkb:Q9VPW0|ensemblmetazoa:FBpp0077658|ensemblmetazoa:FBpp0077659 intact:EBI-122571|uniprotkb:Q9VLL2|ensemblmetazoa:FBpp0079313 psi-mi:star_drome(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:CG4385(orf name) psi-mi:grk_drome(display_long)|uniprotkb:CG17610(orf name)|uniprotkb:grk(gene name)|psi-mi:grk(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873030 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523450.1|refseq:NP_722674.1|flybase:FBgn0003310|dip:DIP-22174N|ensemblmetazoa:FBgn0003310(gene)|ensemblmetazoa:FBtr0077993(transcript)|ensemblmetazoa:FBtr0077994(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007421"(stomatogastric nervous system development)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007601"(visual perception)|go:"GO:0016197"(endosomal transport)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|mint:P42519 dip:DIP-20922N|refseq:NP_476568.2|flybase:FBgn0001137|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008070"(maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:5F5K|rcsb pdb:6PJP|rcsb pdb:6PJQ|rcsb pdb:6PJR|rcsb pdb:6PJU|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|ensemblmetazoa:FBgn0001137(gene)|ensemblmetazoa:FBtr0079708(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space) pubmed:12169630(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8RiR9AUQmUsZN2w2weQ74nTjbls7227 rogid:9TGh46UunwejPDdD4Zxav6Xbl2M7227 intact-crc:089BA9ED8516E45E|rigid:Vky1pDFKmKgDzqKURj/kW19QNiQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9W0F8 uniprotkb:P42287 intact:EBI-159101|ensemblmetazoa:FBpp0072574|uniprotkb:Q9BML3 intact:EBI-122571|uniprotkb:Q9VLL2|ensemblmetazoa:FBpp0079313 psi-mi:q9w0f8_drome(display_long)|uniprotkb:ru(gene name)|psi-mi:ru(display_short)|uniprotkb:Dmel\CG1214(gene name synonym)|uniprotkb:Rho-3(gene name synonym)|uniprotkb:Rho-related [62A1](gene name synonym)|uniprotkb:Rho3(gene name synonym)|uniprotkb:rho-3(gene name synonym)|uniprotkb:rho3(gene name synonym)|uniprotkb:Dmel_CG1214(orf name)|uniprotkb:CG1214(orf name) psi-mi:grk_drome(display_long)|uniprotkb:CG17610(orf name)|uniprotkb:grk(gene name)|psi-mi:grk(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873034 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0003295(gene)|ensemblmetazoa:FBtr0072681(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001752"(compound eye photoreceptor fate commitment)|go:"GO:0003015"(heart process)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|go:"GO:0042676"(compound eye cone cell fate commitment)|go:"GO:0045177"(apical part of cell)|go:"GO:0050714"(positive regulation of protein secretion)|interpro:IPR017213(Peptidase S54, rhomboid, metazoan)|interpro:IPR022764|interpro:IPR035952|refseq:NP_524790.1|flybase:FBgn0003295 dip:DIP-20922N|refseq:NP_476568.2|flybase:FBgn0001137|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008070"(maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:5F5K|rcsb pdb:6PJP|rcsb pdb:6PJQ|rcsb pdb:6PJR|rcsb pdb:6PJU|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|ensemblmetazoa:FBgn0001137(gene)|ensemblmetazoa:FBtr0079708(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space) pubmed:12169630(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Fl5art/krhlG8AxqX+r9kU7Iy1o7227 rogid:9TGh46UunwejPDdD4Zxav6Xbl2M7227 intact-crc:A3D7AC46ADD57C74|rigid:sjRtbBUgqosDeG2Pug7QQfbRiYc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VYW6 uniprotkb:P42287 intact:EBI-108271|ensemblmetazoa:FBpp0073365|ensemblmetazoa:FBpp0073366 intact:EBI-122571|uniprotkb:Q9VLL2|ensemblmetazoa:FBpp0079313 psi-mi:q9vyw6_drome(display_long)|uniprotkb:rho-4(gene name)|psi-mi:rho-4(display_short)|uniprotkb:DmRho4(gene name synonym)|uniprotkb:Dmel\CG1697(gene name synonym)|uniprotkb:Rho-4(gene name synonym)|uniprotkb:Rho-related [10C6](gene name synonym)|uniprotkb:rho 4(gene name synonym)|uniprotkb:rho4(gene name synonym)|uniprotkb:Dmel_CG1697(orf name)|uniprotkb:CG1697(orf name) psi-mi:grk_drome(display_long)|uniprotkb:CG17610(orf name)|uniprotkb:grk(gene name)|psi-mi:grk(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873038 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_727538.1|flybase:FBgn0030318|refseq:NP_525084.1|ensemblmetazoa:FBgn0030318(gene)|ensemblmetazoa:FBtr0073518(transcript)|ensemblmetazoa:FBtr0073519(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR017213(Peptidase S54, rhomboid, metazoan)|interpro:IPR018247|interpro:IPR022764|interpro:IPR035952 dip:DIP-20922N|refseq:NP_476568.2|flybase:FBgn0001137|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008070"(maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:5F5K|rcsb pdb:6PJP|rcsb pdb:6PJQ|rcsb pdb:6PJR|rcsb pdb:6PJU|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|ensemblmetazoa:FBgn0001137(gene)|ensemblmetazoa:FBtr0079708(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space) pubmed:12169630(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:rNG5P1Q+0DjT0WpIkQVw1obOprk7227 rogid:9TGh46UunwejPDdD4Zxav6Xbl2M7227 intact-crc:399698DB3DD58F04|rigid:vIX+S7aIBs5+vRfCTCK/bwuT21I false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42287 uniprotkb:P20350 intact:EBI-122571|uniprotkb:Q9VLL2|ensemblmetazoa:FBpp0079313 intact:EBI-172815|uniprotkb:Q9W0F2|ensemblmetazoa:FBpp0072578|ensemblmetazoa:FBpp0305409 psi-mi:grk_drome(display_long)|uniprotkb:CG17610(orf name)|uniprotkb:grk(gene name)|psi-mi:grk(display_short) psi-mi:rhom_drome(display_long)|uniprotkb:rho(gene name)|psi-mi:rho(display_short)|uniprotkb:Ve(gene name synonym)|uniprotkb:CG1004(orf name)|uniprotkb:Protein veinlet(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873042 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-20922N|refseq:NP_476568.2|flybase:FBgn0001137|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008070"(maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:5F5K|rcsb pdb:6PJP|rcsb pdb:6PJQ|rcsb pdb:6PJR|rcsb pdb:6PJU|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|ensemblmetazoa:FBgn0001137(gene)|ensemblmetazoa:FBtr0079708(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space) refseq:NP_523883.2|flybase:FBgn0004635|refseq:NP_001261255.1|go:"GO:0001752"(compound eye photoreceptor fate commitment)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007436"(larval salivary gland morphogenesis)|go:"GO:0007438"(oenocyte development)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|ensemblmetazoa:FBgn0004635(gene)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035311"(wing cell fate specification)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045177"(apical part of cell)|ensemblmetazoa:FBtr0072694(transcript)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0090317"(negative regulation of intracellular protein transport)|interpro:IPR017213(Peptidase S54, rhomboid, metazoan)|interpro:IPR022764|ensemblmetazoa:FBtr0333207(transcript)|interpro:IPR035952|go:"GO:0000281"(mitotic cytokinesis)|mint:P20350|go:"GO:0001742"(oenocyte differentiation) pubmed:12169630(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:9TGh46UunwejPDdD4Zxav6Xbl2M7227 rogid:1xLHqeP8taUKQZy9DJw9AkfcVr07227 intact-crc:A57E4A058A9660E0|rigid:e4/Fy6J2B4P63L3zpQzSWx2c9Oc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P22711 uniprotkb:P16371 intact:EBI-143325|intact:EBI-1629549|uniprotkb:Q6AWK6|uniprotkb:Q6UKJ7|uniprotkb:Q6UKK8|uniprotkb:Q6UKL1|uniprotkb:Q6UKL4|uniprotkb:Q6UKL5|uniprotkb:Q9TY85|uniprotkb:Q9VDA7|ensemblmetazoa:FBpp0083485 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:tin_drome(display_long)|uniprotkb:tin(gene name)|psi-mi:tin(display_short)|uniprotkb:msh2(gene name synonym)|uniprotkb:CG7895(orf name)|uniprotkb:Msh-2(gene name synonym)|uniprotkb:NK-4(gene name synonym) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873046 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524433.1|flybase:FBgn0004110|ensemblmetazoa:FBgn0004110(gene)|ensemblmetazoa:FBtr0084086(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007280"(pole cell migration)|go:"GO:0007419"(ventral cord development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007552"(metamorphosis)|go:"GO:0008354"(germ cell migration)|go:"GO:0008406"(gonad development)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035051"(cardiocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048542"(lymph gland development)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970 refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N pubmed:10531357(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:5vTbkG0IGgGoekKpC4YuBi2qEfc7227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 intact-crc:08A14E034F546052|rigid:I4SdVCqrKjTqB5qwakSoFpm3SJw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q27350 uniprotkb:P16371 intact:EBI-161504|intact:EBI-1631381|uniprotkb:A0AVT8|uniprotkb:Q9V4L0|ensemblmetazoa:FBpp0089177 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:so_drome(display_long)|uniprotkb:so(gene name)|psi-mi:so(display_short)|uniprotkb:CG11121(orf name) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873050 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476733.1|flybase:FBgn0003460|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008347"(glial cell migration)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0035271"(ring gland development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|ensemblmetazoa:FBgn0003460(gene)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR031701|ensemblmetazoa:FBtr0088970(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001744"(insect visual primordium formation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001746"(Bolwig's organ morphogenesis)|dip:DIP-18228N refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N pubmed:12917324(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:TnP/raOhk9Hfkp45tH8n+HW1UI07227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 intact-crc:08F40A17540C1B89|rigid:r2fC68ymgyF1lrOo0LzqSbtmk3M false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P22814 uniprotkb:P16371 intact:EBI-868309|uniprotkb:A0AVT9|uniprotkb:O76551|uniprotkb:Q6SD78|uniprotkb:Q7KPD6|uniprotkb:Q8MRF4|uniprotkb:Q9TVG1|uniprotkb:Q9TVZ7|uniprotkb:Q9TZQ9|uniprotkb:Q9TZR0|uniprotkb:Q9VRB6|intact:EBI-1639673|ensemblmetazoa:FBpp0076971|ensemblmetazoa:FBpp0311837 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:runt_drome(display_long)|uniprotkb:run(gene name)|psi-mi:run(display_short)|uniprotkb:CG1849(orf name) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873054 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001285501.1|refseq:NP_523424.2|flybase:FBgn0003300|ensemblmetazoa:FBgn0003300(gene)|ensemblmetazoa:FBtr0077279(transcript)|ensemblmetazoa:FBtr0345922(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007377"(germ-band extension)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007419"(ventral cord development)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048592"(eye morphogenesis)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|reactome:R-DME-549127|reactome:R-DME-8878166|reactome:R-DME-8931987|reactome:R-DME-8934593|reactome:R-DME-8936459|reactome:R-DME-8939236|reactome:R-DME-8939243|reactome:R-DME-8939245|reactome:R-DME-8939246|reactome:R-DME-8939247|reactome:R-DME-8939902|reactome:R-DME-8940973|reactome:R-DME-8941326|reactome:R-DME-9018519 refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N pubmed:9706692(see-also)|pubmed:9271433(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:AhHjibxAU093Edu1nQPWbMTKGFo7227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 intact-crc:23F4B2FC39E23A4E|rigid:IYAdMU40RSLHUF25MILWglEJQd4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q94517 uniprotkb:P16371 intact:EBI-302197|uniprotkb:O17429|uniprotkb:O77213|uniprotkb:Q9VZA1|ensemblmetazoa:FBpp0073173 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:hdac1_drome(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:Rpd3(gene name synonym)|uniprotkb:CG7471(orf name) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873058 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0015805(gene)|ensemblmetazoa:FBtr0073317(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070983"(dendrite guidance)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0031523"(Myb complex)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q94517|reactome:R-DME-1538133|reactome:R-DME-201722|reactome:R-DME-209394|reactome:R-DME-3214815|reactome:R-DME-3769402|reactome:R-DME-6804758|reactome:R-DME-8943724|reactome:R-DME-983231|refseq:NP_647918.2|flybase:FBgn0015805|dip:DIP-29512N refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N pubmed:10485845(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:HYHCai8wP8lueOr33vYY32w2pHU7227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 intact-crc:04D007E8CB8FC690|rigid:AfEprqQPS1EN8jyDOOkdZEwIqEQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24573 uniprotkb:P16371 intact:EBI-414771|ensemblmetazoa:FBpp0071982|uniprotkb:Q8MSB0|uniprotkb:Q9W1M0 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:dri_drome(display_long)|uniprotkb:retn(gene name)|psi-mi:retn(display_short)|uniprotkb:dri(gene name synonym)|uniprotkb:CG5403(orf name)|uniprotkb:Protein retained(gene name synonym) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873062 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0004795(gene)|ensemblmetazoa:FBtr0072073(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007411"(axon guidance)|go:"GO:0007431"(salivary gland development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008049"(male courtship behavior)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042063"(gliogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045924"(regulation of female receptivity)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|interpro:IPR036431|rcsb pdb:1C20|rcsb pdb:1KQQ|refseq:NP_476864.2|refseq:NP_788434.1|flybase:FBgn0004795 refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N pubmed:9774673(see-also)|pubmed:10660305(see-also)|pubmed:9774673(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:1twnhx8btDlgRarJrkt+OvwpmRg7227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 intact-crc:87BC4FBD4AA8E3BD|rigid:lXrXyqqRBmUAqhNzMgz8W6J0RWs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P91943 uniprotkb:P16371 intact:EBI-147301|uniprotkb:O02548|uniprotkb:Q0KIE9|intact:EBI-1629313|uniprotkb:Q59DP5|uniprotkb:Q5BHZ3|uniprotkb:Q6W492|uniprotkb:Q6W493|uniprotkb:Q6W494|uniprotkb:Q6W495|uniprotkb:Q6W4A6|uniprotkb:Q6W4B4|uniprotkb:Q9V4B0|uniprotkb:A0AVW4|uniprotkb:A4V148|uniprotkb:B5RJS3|ensemblmetazoa:FBpp0088226|ensemblmetazoa:FBpp0088228|ensemblmetazoa:FBpp0088229|ensemblmetazoa:FBpp0301556 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:pang1_drome(display_long)|uniprotkb:pan(gene name)|psi-mi:pan(display_short)|uniprotkb:TCF(gene name synonym)|uniprotkb:dTCF(gene name synonym)|uniprotkb:CG34403(orf name) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873066 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245406.1|refseq:NP_001014685.1|refseq:NP_001033798.1|refseq:NP_524619.3|refseq:NP_726522.1|refseq:NP_726524.1|flybase:FBgn0085432|refseq:NP_726527.2|dip:DIP-19970N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019900"(kinase binding)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR028782|interpro:IPR036910|reactome:R-DME-209421|reactome:R-DME-209441|ensemblmetazoa:FBgn0085432(gene)|ensemblmetazoa:FBtr0089159(transcript)|ensemblmetazoa:FBtr0089161(transcript)|ensemblmetazoa:FBtr0089162(transcript)|ensemblmetazoa:FBtr0309803(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific) refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N pubmed:9783586(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:H6BhYVP6spDgW8etHP7+/L29jO87227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 intact-crc:173E7274A67AD6C2|rigid:ltrEc0yaqfrBkSELGiuzyJmRX5o false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KNM2 uniprotkb:P16371 intact:EBI-74966|intact:EBI-1627711|ensemblmetazoa:FBpp0077741|ensemblmetazoa:FBpp0077742|ensemblmetazoa:FBpp0301731|ensemblmetazoa:FBpp0301732 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:q7knm2_drome(display_long)|uniprotkb:lwr(gene name)|psi-mi:lwr(display_short)|uniprotkb:semi(gene name synonym)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:DUbc9(gene name synonym)|uniprotkb:DmUbc9(gene name synonym)|uniprotkb:Dmel\CG3018(gene name synonym)|uniprotkb:Dmubc9(gene name synonym)|uniprotkb:FBgn0010602(gene name synonym)|uniprotkb:Iwr(gene name synonym)|uniprotkb:Lwr(gene name synonym)|uniprotkb:Ubc 9(gene name synonym)|uniprotkb:Ubc-9(gene name synonym)|uniprotkb:UbcD9(gene name synonym)|uniprotkb:dUBC9(gene name synonym)|uniprotkb:dUbc9(gene name synonym)|uniprotkb:dip4(gene name synonym)|uniprotkb:hbl(gene name synonym)|uniprotkb:i105(gene name synonym)|uniprotkb:i56(gene name synonym)|uniprotkb:"l(2)01519"(gene name synonym)|uniprotkb:"l(2)02858"(gene name synonym)|uniprotkb:"l(2)05486"(gene name synonym)|uniprotkb:"l(2)05487"(gene name synonym)|uniprotkb:ubc9(gene name synonym)|uniprotkb:Dmel_CG3018(orf name)|uniprotkb:UBC9(gene name synonym)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:CG3018(orf name) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873070 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476978.1|refseq:NP_722637.1|flybase:FBgn0010602|refseq:NP_001259833.1|refseq:NP_001259834.1|ensemblmetazoa:FBgn0010602(gene)|ensemblmetazoa:FBtr0078081(transcript)|ensemblmetazoa:FBtr0078082(transcript)|ensemblmetazoa:FBtr0310028(transcript)|ensemblmetazoa:FBtr0310029(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000940"(outer kinetochore)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007391"(dorsal closure)|go:"GO:0008354"(germ cell migration)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030721"(spectrosome organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033134"(ubiquitin activating enzyme binding)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0035207"(negative regulation of hemocyte proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0140540"(negative regulation melanotic encapsulation of foreign target)|go:"GO:1904677"(positive regulation of somatic stem cell division)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-196791|reactome:R-DME-3108214|reactome:R-DME-3232118|reactome:R-DME-3899300|reactome:R-DME-4090294|reactome:R-DME-4551638|reactome:R-DME-4570464|reactome:R-DME-4615885|reactome:R-DME-4755510|reactome:R-DME-5696395 refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N pubmed:9990118(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:0klFCJX3ACVlfPFXyh4vl9degjM7227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 intact-crc:B0D823F9CDBBC129|rigid:8cThvSPAIF+N0/4zVoyE1dsnDdk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VN10 uniprotkb:P16371 intact:EBI-171756|ensemblmetazoa:FBpp0078591 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:q9vn10_drome(display_long)|uniprotkb:hkb(gene name)|psi-mi:hkb(display_short)|uniprotkb:CG9768(orf name)|uniprotkb:5953(gene name synonym)|uniprotkb:Dmel\CG9768(gene name synonym)|uniprotkb:HKB(gene name synonym)|uniprotkb:Hkb(gene name synonym)|uniprotkb:anon-82B3(gene name synonym)|uniprotkb:gurt(gene name synonym)|uniprotkb:Dmel_CG9768(orf name) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873078 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524221.1|flybase:FBgn0261434|dip:DIP-22721N|ensemblmetazoa:FBgn0261434(gene)|ensemblmetazoa:FBtr0078951(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007374"(posterior midgut invagination)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007431"(salivary gland development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007492"(endoderm development)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0061024"(membrane organization)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9VN10 refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N pubmed:10433905(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Qs1bZL0BQWORAvcmyIj/KJ/LDWQ7227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 intact-crc:D7EA558FE9DD1C1B|rigid:Mt4CRiONXfmlAmBSvfzj9eAlB+g false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P02299 uniprotkb:P16371 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873082 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231 refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N pubmed:11058116(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 intact-crc:3943744A199BB5CA|rigid:9DLf0bRxIZGnuTZDwbszSD2uqzs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q02308 uniprotkb:P16371 intact:EBI-222848|uniprotkb:Q9VDK0|uniprotkb:Q9VDK1|uniprotkb:A4V358|uniprotkb:A4V359|uniprotkb:Q6AWM8|uniprotkb:Q960W5|ensemblmetazoa:FBpp0083322|ensemblmetazoa:FBpp0083324 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:hles_drome(display_long)|uniprotkb:H(gene name)|psi-mi:H(display_short)|uniprotkb:CG5460(orf name) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873086 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524418.2|refseq:NP_732533.1|refseq:NP_732534.1|refseq:NP_732535.1|flybase:FBgn0001169|dip:DIP-39152N|ensemblmetazoa:FBgn0001169(gene)|ensemblmetazoa:FBtr0083914(transcript)|ensemblmetazoa:FBtr0083916(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0008052"(sensory organ boundary specification)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|rcsb pdb:5E24 refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N pubmed:12154126(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:TM6PF6mRjXrOiWFNPSPfb6oLYhg7227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 intact-crc:C01D57E952D6AE66|rigid:PhnX8jDX38iZZgwtjx83/gnYNl0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P14003 uniprotkb:P16371 intact:EBI-123011|intact:EBI-1639662|uniprotkb:A4V1N7|uniprotkb:Q95NH3|uniprotkb:Q95NU9|uniprotkb:Q9VSN8|ensemblmetazoa:FBpp0076296|ensemblmetazoa:FBpp0099504 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:hair_drome(display_long)|uniprotkb:CG6494(orf name)|uniprotkb:h(gene name)|psi-mi:h(display_short) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873090 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014577.1|refseq:NP_523977.2|flybase:FBgn0001168|ensemblmetazoa:FBgn0001168(gene)|ensemblmetazoa:FBtr0076569(transcript)|ensemblmetazoa:FBtr0100153(transcript)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0035290"(trunk segmentation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061024"(membrane organization)|go:"GO:0070888"(E-box binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P14003|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|dip:DIP-637N refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N pubmed:8649374(see-also)|pubmed:8001118(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:bO023bTsk72HhqvmgSjLEIotrDw7227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 intact-crc:7361A6777B679467|rigid:FHdrglr3JteKqIwUuxGzJp7BT8k false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P54366 uniprotkb:P16371 intact:EBI-137040|uniprotkb:Q9VPR9|ensemblmetazoa:FBpp0309909 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:gsc_drome(display_long)|uniprotkb:Gsc(gene name)|psi-mi:Gsc(display_short)|uniprotkb:CG2851(orf name) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873094 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0010323|refseq:NP_476949.2|ensemblmetazoa:FBgn0010323(gene)|ensemblmetazoa:FBtr0343220(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970 refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N pubmed:10022895(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2016/03/30 rogid:kupwrcWKe0z+NyQLkSRubaVkk6U7227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 intact-crc:2336CB75B536199E|rigid:SdDbMR5RnCq9Ahk7fmaptcMBTg8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09491 uniprotkb:P41043 intact:EBI-233791|uniprotkb:P09490|uniprotkb:Q24408|uniprotkb:Q24427|uniprotkb:Q24428|uniprotkb:Q8SZ65|uniprotkb:Q9VF95|uniprotkb:A0AVW5|uniprotkb:A4V2Y6|ensemblmetazoa:FBpp0089270 intact:EBI-116140|uniprotkb:Q0E945|ensemblmetazoa:FBpp0086156|ensemblmetazoa:FBpp0086157|ensemblmetazoa:FBpp0099646|uniprotkb:Q9V7Y4 psi-mi:tpm2_drome(display_long)|uniprotkb:Tm2(gene name)|psi-mi:Tm2(display_short)|uniprotkb:TmI(gene name synonym)|uniprotkb:CG4843(orf name)|uniprotkb:Tropomyosin I(gene name synonym) psi-mi:gsts1_drome(display_long)|uniprotkb:GST2(gene name synonym)|uniprotkb:CG8938(orf name)|uniprotkb:GST class-sigma 1(gene name synonym)|uniprotkb:GstS1(gene name)|psi-mi:GstS1(display_short)|uniprotkb:Glutathione S-transferase 2(gene name synonym)|uniprotkb:GSTS1-1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873098 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524361.4|refseq:NP_732012.1|refseq:NP_732013.2|flybase:FBgn0004117|refseq:NP_001287337.1|refseq:NP_001262592.1|refseq:NP_001262593.1|dip:DIP-21556N|ensemblmetazoa:FBgn0004117(gene)|ensemblmetazoa:FBtr0083080(transcript)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007507"(heart development)|go:"GO:0051015"(actin filament binding)|go:"GO:0060298"(positive regulation of sarcomere organization)|interpro:IPR000533(Tropomyosin)|reactome:R-DME-9013424 ensemblmetazoa:FBgn0010226(gene)|ensemblmetazoa:FBtr0087005(transcript)|ensemblmetazoa:FBtr0087006(transcript)|ensemblmetazoa:FBtr0100258(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004667"(prostaglandin-D synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006749"(glutathione metabolic process)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1M0U|reactome:R-DME-156590|reactome:R-DME-2162123|refseq:NP_523767.2|refseq:NP_725653.1|refseq:NP_725654.1|flybase:FBgn0010226|dip:DIP-21396N pubmed:9536439(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:U0ue0JykMFrmEJSiXLUGPRMvF9g7227 rogid:dHo8E2U/t+pgrYxxFZDXMjIZMFM7227 intact-crc:13760659041922BB|rigid:13nk/sc5ow26vyB5aQ4fI83yJio false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09052 uniprotkb:A1Z6E0 intact:EBI-134067|uniprotkb:Q24582|uniprotkb:Q8SXU8|uniprotkb:Q9V3Q8|ensemblmetazoa:FBpp0401445|ensemblmetazoa:FBpp0401446|ensemblmetazoa:FBpp0401447 intact:EBI-75338|uniprotkb:A1Z6D7|uniprotkb:A1Z6D9|uniprotkb:A1Z6E2|uniprotkb:F2FB59|uniprotkb:Q7JUY1|intact:EBI-1630026|intact:EBI-3406983|intact:EBI-466537|intact:EBI-869694|intact:EBI-9944856|ensemblmetazoa:FBpp0301580|ensemblmetazoa:FBpp0301581|ensemblmetazoa:FBpp0301582|ensemblmetazoa:FBpp0301583|ensemblmetazoa:FBpp0301584|ensemblmetazoa:FBpp0301585|ensemblmetazoa:FBpp0301586 psi-mi:vasa1_drome(display_long)|uniprotkb:vas(gene name)|psi-mi:vas(display_short)|uniprotkb:Antigen Mab46F11(gene name synonym)|uniprotkb:vasa(gene name synonym)|uniprotkb:CG46283(orf name) psi-mi:gus_drome(display_long)|uniprotkb:gus(gene name)|psi-mi:gus(display_short)|uniprotkb:CG2944(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283442|refseq:NP_723899.1|refseq:NP_001303322.1|refseq:NP_001260458.1|ensemblmetazoa:FBgn0283442(gene)|rcsb pdb:2IHS|rcsb pdb:3EMW|rcsb pdb:3F2O|rcsb pdb:5NT7|ensemblmetazoa:FBtr0445185(transcript)|ensemblmetazoa:FBtr0445186(transcript)|ensemblmetazoa:FBtr0445187(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0008104"(protein localization)|go:"GO:0030154"(cell differentiation)|go:"GO:0043073"(germ cell nucleus)|go:"GO:0043186"(P granule)|go:"GO:0048477"(oogenesis)|go:"GO:0061803"(posterior cell cortex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|mint:P09052|rcsb pdb:2DB3|dip:DIP-20604N refseq:NP_001246140.1|refseq:NP_610158.3|refseq:NP_724398.2|refseq:NP_724399.2|refseq:NP_724400.2|refseq:NP_724401.2|refseq:NP_724402.2|flybase:FBgn0026238|ensemblmetazoa:FBgn0026238(gene)|ensemblmetazoa:FBtr0309846(transcript)|ensemblmetazoa:FBtr0309847(transcript)|ensemblmetazoa:FBtr0309848(transcript)|ensemblmetazoa:FBtr0309849(transcript)|ensemblmetazoa:FBtr0309850(transcript)|ensemblmetazoa:FBtr0309851(transcript)|ensemblmetazoa:FBtr0309852(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007280"(pole cell migration)|go:"GO:0007281"(germ cell development)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045495"(pole plasm)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070449"(elongin complex)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR036036|interpro:IPR043136|mint:A1Z6E0|rcsb pdb:2FNJ|rcsb pdb:2IHS|reactome:R-DME-8951664|reactome:R-DME-983168 pubmed:12479811(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2016/03/30 rogid:MPzIr/Dex98V189t6FOs8l0nQnM7227 rogid:4qRmm2ryCinfjDMxKUZ30fn5cpQ7227 intact-crc:87FCF0DA88155A5C|rigid:iFModAC2ZqZHVk5vrBT/Y7H3oUI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P28159 uniprotkb:Q02308 intact:EBI-92180|uniprotkb:Q3S1M8|uniprotkb:Q9TVK8|uniprotkb:Q9TVY7|uniprotkb:Q9TW34|uniprotkb:Q9U8F9|uniprotkb:Q9V446|ensemblmetazoa:FBpp0080261|ensemblmetazoa:FBpp0312201 intact:EBI-222848|uniprotkb:Q9VDK0|uniprotkb:Q9VDK1|uniprotkb:A4V358|uniprotkb:A4V359|uniprotkb:Q6AWM8|uniprotkb:Q960W5|ensemblmetazoa:FBpp0083322|ensemblmetazoa:FBpp0083324 psi-mi:suh_drome(display_long)|uniprotkb:"Su(H)"(gene name)|psi-mi:"Su(H)"(display_short)|uniprotkb:dRBP-JK(gene name synonym)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym)|uniprotkb:CG3497(orf name) psi-mi:hles_drome(display_long)|uniprotkb:H(gene name)|psi-mi:H(display_short)|uniprotkb:CG5460(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873110 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001285948.1|refseq:NP_476868.1|flybase:FBgn0004837|ensemblmetazoa:FBgn0004837(gene)|ensemblmetazoa:FBtr0080700(transcript)|ensemblmetazoa:FBtr0346621(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007616"(long-term memory)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042683"(negative regulation of compound eye cone cell fate specification)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1990433"(CSL-Notch-Mastermind transcription factor complex)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|rcsb pdb:5E24|dip:DIP-177N refseq:NP_524418.2|refseq:NP_732533.1|refseq:NP_732534.1|refseq:NP_732535.1|flybase:FBgn0001169|dip:DIP-39152N|ensemblmetazoa:FBgn0001169(gene)|ensemblmetazoa:FBtr0083914(transcript)|ensemblmetazoa:FBtr0083916(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0008052"(sensory organ boundary specification)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|rcsb pdb:5E24 pubmed:8050354(see-also)|pubmed:8742832(see-also)|pubmed:9518521(see-also)|pubmed:7958912(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:3NFMvvrfh1WC+s9QwiDW5BCUr5I7227 rogid:TM6PF6mRjXrOiWFNPSPfb6oLYhg7227 intact-crc:BDF8B89906D164E3|rigid:EjBkI1sTxPbi0AfpKusZjIXKfrU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VK34 uniprotkb:P14003 intact:EBI-83837|ensemblmetazoa:FBpp0080015|intact:EBI-869173|uniprotkb:D5SHQ6|uniprotkb:O96505 intact:EBI-123011|intact:EBI-1639662|uniprotkb:A4V1N7|uniprotkb:Q95NH3|uniprotkb:Q95NU9|uniprotkb:Q9VSN8|ensemblmetazoa:FBpp0076296|ensemblmetazoa:FBpp0099504 psi-mi:sirt1_drome(display_long)|uniprotkb:Sirt1(gene name)|psi-mi:Sirt1(display_short)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Sir2(gene name synonym)|uniprotkb:CG5216(orf name) psi-mi:hair_drome(display_long)|uniprotkb:CG6494(orf name)|uniprotkb:h(gene name)|psi-mi:h(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873114 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0024291(gene)|ensemblmetazoa:FBtr0080434(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016740"(transferase activity)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046872"(metal ion binding)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:1901416"(regulation of response to ethanol)|go:"GO:2000253"(positive regulation of feeding behavior)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|reactome:R-DME-9617629|refseq:NP_477351.1|flybase:FBgn0024291 refseq:NP_001014577.1|refseq:NP_523977.2|flybase:FBgn0001168|ensemblmetazoa:FBgn0001168(gene)|ensemblmetazoa:FBtr0076569(transcript)|ensemblmetazoa:FBtr0100153(transcript)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0035290"(trunk segmentation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061024"(membrane organization)|go:"GO:0070888"(E-box binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P14003|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|dip:DIP-637N pubmed:12086602(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:c+w67u0SypZji7O8yy/JsMFtAeA7227 rogid:bO023bTsk72HhqvmgSjLEIotrDw7227 intact-crc:C81D2965C2844915|rigid:u9D4/fQJ/cjjSLi04VMOgNtNf4Y false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O97159 uniprotkb:P05084 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 intact:EBI-176716|uniprotkb:Q24018|uniprotkb:Q29R06|uniprotkb:Q960U7|ensemblmetazoa:FBpp0081431|ensemblmetazoa:FBpp0081432 psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:hunb_drome(display_long)|uniprotkb:hb(gene name)|psi-mi:hb(display_short)|uniprotkb:CG9786(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724 refseq:NP_731267.1|refseq:NP_731268.1|flybase:FBgn0001180|dip:DIP-17417N|ensemblmetazoa:FBgn0001180(gene)|go:"GO:0035290"(trunk segmentation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048699"(generation of neurons)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027742|interpro:IPR036236|reactome:R-DME-8951664|reactome:R-DME-983168|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007402"(ganglion mother cell fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007431"(salivary gland development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0035289"(posterior head segmentation)|ensemblmetazoa:FBtr0081950(transcript)|ensemblmetazoa:FBtr0081951(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity) pubmed:9836641(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 rogid:bMrJj8RnVLaTRujTf/pBJJkRlL47227 intact-crc:2AEB2642DE5C55E7|rigid:0wO+L0GortXLLIl2KxmI1PFCjqY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07247 uniprotkb:P05084 intact:EBI-672843|uniprotkb:Q8SYW3|uniprotkb:Q9W0V9|ensemblmetazoa:FBpp0072351|ensemblmetazoa:FBpp0305365 intact:EBI-176716|uniprotkb:Q24018|uniprotkb:Q29R06|uniprotkb:Q960U7|ensemblmetazoa:FBpp0081431|ensemblmetazoa:FBpp0081432 psi-mi:krup_drome(display_long)|uniprotkb:Kr(gene name)|psi-mi:Kr(display_short)|uniprotkb:CG3340(orf name) psi-mi:hunb_drome(display_long)|uniprotkb:hb(gene name)|psi-mi:hb(display_short)|uniprotkb:CG9786(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523867.1|flybase:FBgn0001325|refseq:NP_001261181.1|ensemblmetazoa:FBgn0001325(gene)|ensemblmetazoa:FBtr0072449(transcript)|ensemblmetazoa:FBtr0333162(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007517"(muscle organ development)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061332"(Malpighian tubule bud morphogenesis)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR031243|interpro:IPR036236 refseq:NP_731267.1|refseq:NP_731268.1|flybase:FBgn0001180|dip:DIP-17417N|ensemblmetazoa:FBgn0001180(gene)|go:"GO:0035290"(trunk segmentation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048699"(generation of neurons)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027742|interpro:IPR036236|reactome:R-DME-8951664|reactome:R-DME-983168|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007402"(ganglion mother cell fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007431"(salivary gland development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0035289"(posterior head segmentation)|ensemblmetazoa:FBtr0081950(transcript)|ensemblmetazoa:FBtr0081951(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity) pubmed:7588607(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:r0X90GV+LseJkjX0mKqmA6xjcns7227 rogid:bMrJj8RnVLaTRujTf/pBJJkRlL47227 intact-crc:8B105AF0AD201BBD|rigid:Na1jGs+NJf+MPVjEN2MvdUt07Hc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O97174 uniprotkb:A1Z9X4 intact:EBI-869721 intact:EBI-869704|ensemblmetazoa:FBpp0086545|ensemblmetazoa:FBpp0311546 psi-mi:o97174_drome(display_long)|uniprotkb:kirre(gene name)|psi-mi:kirre(display_short)|uniprotkb:"EG:163A10.1"(gene name synonym)|uniprotkb:CG3653(orf name) psi-mi:a1z9x4_drome(display_long)|uniprotkb:hbs(gene name)|psi-mi:hbs(display_short)|uniprotkb:CT22841(gene name synonym)|uniprotkb:Dmel\CG7449(gene name synonym)|uniprotkb:Hbs(gene name synonym)|uniprotkb:icon(gene name synonym)|uniprotkb:CG7449(orf name)|uniprotkb:Dmel_CG7449(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873126 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028369|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005917"(nephrocyte diaphragm)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007523"(larval visceral muscle development)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0036058"(filtration diaphragm assembly)|go:"GO:0036059"(nephrocyte diaphragm assembly)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0061321"(garland nephrocyte differentiation)|go:"GO:0097206"(nephrocyte filtration)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1901739"(regulation of myoblast fusion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179 refseq:NP_788355.1|flybase:FBgn0287864|refseq:NP_001286439.1|ensemblmetazoa:FBgn0029082(gene)|ensemblmetazoa:FBtr0087414(transcript)|ensemblmetazoa:FBtr0345419(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0061330"(Malpighian tubule stellate cell differentiation)|go:"GO:0098631"(cell adhesion mediator activity)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179 pubmed:11684662(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+OQs2IWpBbhQza2pX+eCNpeFLYs7227 rogid:5uDJtUysLZbdmaRV1roU7Rkoxws7227 intact-crc:425A060CC153C281|rigid:xexeEJuuAmfCkgsUnjGvddyobH4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P91682 uniprotkb:Q02936 intact:EBI-142245|uniprotkb:Q9VPM8|uniprotkb:B7FNK1|ensemblmetazoa:FBpp0077788 intact:EBI-499194|uniprotkb:A4V396|uniprotkb:Q9VCQ4|ensemblmetazoa:FBpp0099945 psi-mi:smo_drome(display_long)|uniprotkb:smo(gene name)|psi-mi:smo(display_short)|uniprotkb:CG11561(orf name)|uniprotkb:dSMO(gene name synonym)|uniprotkb:SMOH(gene name synonym)|uniprotkb:Smooth(gene name synonym) psi-mi:hh_drome(display_long)|uniprotkb:hh(gene name)|psi-mi:hh(display_short)|uniprotkb:CG4637(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873130 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523443.1|flybase:FBgn0003444|dip:DIP-19956N|ensemblmetazoa:FBgn0003444(gene)|ensemblmetazoa:FBtr0078129(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0002385"(mucosal immune response)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005113"(patched binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048099"(anterior/posterior lineage restriction, imaginal disc)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026544|interpro:IPR035683|interpro:IPR036790|interpro:IPR041771|rcsb pdb:2MAH|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-216119|reactome:R-DME-216217|reactome:R-DME-5610787|reactome:R-DME-5620922|reactome:R-DME-5635838 refseq:NP_001034065.1|flybase:FBgn0004644|dip:DIP-51313N|ensemblmetazoa:FBgn0004644(gene)|ensemblmetazoa:FBtr0100506(transcript)|go:"GO:0001708"(cell fate specification)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002385"(mucosal immune response)|go:"GO:0005113"(patched binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007280"(pole cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007418"(ventral midline development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0007473"(wing disc proximal/distal pattern formation)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0007487"(analia development)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008347"(glial cell migration)|go:"GO:0008354"(germ cell migration)|go:"GO:0008544"(epidermis development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016015"(morphogen activity)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0035154"(terminal cell fate specification, open tracheal system)|go:"GO:0035215"(genital disc development)|go:"GO:0035217"(labial disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035231"(cytoneme assembly)|go:"GO:0035232"(germ cell attraction)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035288"(anterior head segmentation)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045168"(cell-cell signaling involved in cell fate commitment)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048099"(anterior/posterior lineage restriction, imaginal disc)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0060914"(heart formation)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR000320(Hedgehog amino-terminal signaling region)|interpro:IPR001657(Peptidase C46, hedgehog protein)|interpro:IPR001767(Peptidase C46, hedgehog protein, hint region)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR006141(Intein splicing site)|interpro:IPR009045(Hedgehog/DD-peptidase, zinc-binding motif)|interpro:IPR036844|rcsb pdb:1AT0|rcsb pdb:2IBG|rcsb pdb:6TD6|rcsb pdb:6TYY|reactome:R-DME-209338|reactome:R-DME-209471|reactome:R-DME-5358346|reactome:R-DME-5362798|reactome:R-DME-5632681 pubmed:8898207(see-also)|pubmed:8700230(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:B/9O3wxDY6qY2W709uuH3tz1XTY7227 rogid:dXfS1AFla3efAqH2ITEHX65v0PQ7227 intact-crc:DC79486BC68B9D7D|rigid:OptLZmdKslBKJqUbiW3vs/31rns false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VZU2 uniprotkb:Q02936 intact:EBI-117067|uniprotkb:Q95VY0|ensemblmetazoa:FBpp0072893 intact:EBI-499194|uniprotkb:A4V396|uniprotkb:Q9VCQ4|ensemblmetazoa:FBpp0099945 psi-mi:hhat_drome(display_long)|uniprotkb:Protein central missing(gene name synonym)|uniprotkb:Protein sightless(gene name synonym)|uniprotkb:Protein skinny hedgehog(gene name synonym)|uniprotkb:rasp(gene name)|psi-mi:rasp(display_short)|uniprotkb:ski(gene name synonym)|uniprotkb:sit(gene name synonym)|uniprotkb:CG11495(orf name)|uniprotkb:cmn(gene name synonym) psi-mi:hh_drome(display_long)|uniprotkb:hh(gene name)|psi-mi:hh(display_short)|uniprotkb:CG4637(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873134 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0024194(gene)|ensemblmetazoa:FBtr0073029(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007225"(patched ligand maturation)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0018009"(N-terminal peptidyl-L-cysteine N-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|reactome:R-DME-209471|reactome:R-DME-5358346|refseq:NP_523898.1|flybase:FBgn0024194 refseq:NP_001034065.1|flybase:FBgn0004644|dip:DIP-51313N|ensemblmetazoa:FBgn0004644(gene)|ensemblmetazoa:FBtr0100506(transcript)|go:"GO:0001708"(cell fate specification)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002385"(mucosal immune response)|go:"GO:0005113"(patched binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007280"(pole cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007418"(ventral midline development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0007473"(wing disc proximal/distal pattern formation)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0007487"(analia development)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008347"(glial cell migration)|go:"GO:0008354"(germ cell migration)|go:"GO:0008544"(epidermis development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016015"(morphogen activity)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0035154"(terminal cell fate specification, open tracheal system)|go:"GO:0035215"(genital disc development)|go:"GO:0035217"(labial disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035231"(cytoneme assembly)|go:"GO:0035232"(germ cell attraction)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035288"(anterior head segmentation)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045168"(cell-cell signaling involved in cell fate commitment)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048099"(anterior/posterior lineage restriction, imaginal disc)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0060914"(heart formation)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR000320(Hedgehog amino-terminal signaling region)|interpro:IPR001657(Peptidase C46, hedgehog protein)|interpro:IPR001767(Peptidase C46, hedgehog protein, hint region)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR006141(Intein splicing site)|interpro:IPR009045(Hedgehog/DD-peptidase, zinc-binding motif)|interpro:IPR036844|rcsb pdb:1AT0|rcsb pdb:2IBG|rcsb pdb:6TD6|rcsb pdb:6TYY|reactome:R-DME-209338|reactome:R-DME-209471|reactome:R-DME-5358346|reactome:R-DME-5362798|reactome:R-DME-5632681 pubmed:11861468(see-also)|pubmed:11486055(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:zsM9b3wdS/ZmFi2l2obnIo5SrKI7227 rogid:dXfS1AFla3efAqH2ITEHX65v0PQ7227 intact-crc:81D66325E4796659|rigid:P8qdNMPs2TTGqVZO3qQmYCea2Vs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18502 uniprotkb:Q02936 intact:EBI-140029|uniprotkb:Q9V4W3|ensemblmetazoa:FBpp0088443 intact:EBI-499194|uniprotkb:A4V396|uniprotkb:Q9VCQ4|ensemblmetazoa:FBpp0099945 psi-mi:ptc_drome(display_long)|uniprotkb:ptc(gene name)|psi-mi:ptc(display_short)|uniprotkb:CG2411(orf name)|uniprotkb:Hedgehog receptor(gene name synonym) psi-mi:hh_drome(display_long)|uniprotkb:hh(gene name)|psi-mi:hh(display_short)|uniprotkb:CG4637(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873138 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523661.2|flybase:FBgn0003892|dip:DIP-634N|ensemblmetazoa:FBgn0003892(gene)|ensemblmetazoa:FBtr0089427(transcript)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0005119"(smoothened binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008158"(hedgehog receptor activity)|go:"GO:0008406"(gonad development)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048099"(anterior/posterior lineage restriction, imaginal disc)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0097108"(hedgehog family protein binding)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|interpro:IPR004766(Transmembrane receptor, patched)|reactome:R-DME-209338|reactome:R-DME-5610787|reactome:R-DME-5632681|reactome:R-DME-5632684 refseq:NP_001034065.1|flybase:FBgn0004644|dip:DIP-51313N|ensemblmetazoa:FBgn0004644(gene)|ensemblmetazoa:FBtr0100506(transcript)|go:"GO:0001708"(cell fate specification)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002385"(mucosal immune response)|go:"GO:0005113"(patched binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007280"(pole cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007418"(ventral midline development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0007473"(wing disc proximal/distal pattern formation)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0007487"(analia development)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008347"(glial cell migration)|go:"GO:0008354"(germ cell migration)|go:"GO:0008544"(epidermis development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016015"(morphogen activity)|go:"GO:0016335"(morphogenesis of larval imaginal disc epithelium)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0035154"(terminal cell fate specification, open tracheal system)|go:"GO:0035215"(genital disc development)|go:"GO:0035217"(labial disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035231"(cytoneme assembly)|go:"GO:0035232"(germ cell attraction)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035288"(anterior head segmentation)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045168"(cell-cell signaling involved in cell fate commitment)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048099"(anterior/posterior lineage restriction, imaginal disc)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0060914"(heart formation)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR000320(Hedgehog amino-terminal signaling region)|interpro:IPR001657(Peptidase C46, hedgehog protein)|interpro:IPR001767(Peptidase C46, hedgehog protein, hint region)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR006141(Intein splicing site)|interpro:IPR009045(Hedgehog/DD-peptidase, zinc-binding motif)|interpro:IPR036844|rcsb pdb:1AT0|rcsb pdb:2IBG|rcsb pdb:6TD6|rcsb pdb:6TYY|reactome:R-DME-209338|reactome:R-DME-209471|reactome:R-DME-5358346|reactome:R-DME-5362798|reactome:R-DME-5632681 pubmed:8898207(see-also)|pubmed:8906787(see-also)|pubmed:9811578(see-also)|pubmed:15300262(see-also)|pubmed:1653906(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:nSgw0TMBaqz8EOXgCCXdvffepz07227 rogid:dXfS1AFla3efAqH2ITEHX65v0PQ7227 intact-crc:E974F1C01CC17945|rigid:lSX3Y5S7skrIcW/Y1VEfzWdQQNw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P02255 uniprotkb:P51123 intact:EBI-151629|uniprotkb:Q4ABD3|ensemblmetazoa:FBpp0085248|ensemblmetazoa:FBpp0091052|ensemblmetazoa:FBpp0091057|ensemblmetazoa:FBpp0091059|ensemblmetazoa:FBpp0091062|ensemblmetazoa:FBpp0091065|ensemblmetazoa:FBpp0091068|ensemblmetazoa:FBpp0091071|ensemblmetazoa:FBpp0091074|ensemblmetazoa:FBpp0091077|ensemblmetazoa:FBpp0091083|ensemblmetazoa:FBpp0091086|ensemblmetazoa:FBpp0091089|ensemblmetazoa:FBpp0091092|ensemblmetazoa:FBpp0091095|ensemblmetazoa:FBpp0091098|ensemblmetazoa:FBpp0091110 intact:EBI-499582|uniprotkb:O97068|uniprotkb:Q7KSX6|uniprotkb:Q7KSX7|uniprotkb:Q86LF7|uniprotkb:Q9TX96|ensemblmetazoa:FBpp0089369 psi-mi:h1_drome(display_long)|uniprotkb:His1(gene name)|psi-mi:His1(display_short)|uniprotkb:"His1:CG31617"(gene name)|psi-mi:"His1:CG31617"(display_short)|uniprotkb:"His1:CG33846"(gene name)|psi-mi:"His1:CG33846"(display_short)|uniprotkb:"His1:CG33849"(gene name)|psi-mi:"His1:CG33849"(display_short)|uniprotkb:"His1:CG33852"(gene name)|psi-mi:"His1:CG33852"(display_short)|uniprotkb:"His1:CG33864"(gene name)|psi-mi:"His1:CG33864"(display_short)|uniprotkb:CG31617(orf name)|uniprotkb:CG33804(orf name)|uniprotkb:CG33810(orf name)|uniprotkb:CG33813(orf name)|uniprotkb:CG33816(orf name)|uniprotkb:CG33819(orf name)|uniprotkb:CG33822(orf name)|uniprotkb:CG33825(orf name)|uniprotkb:CG33828(orf name)|uniprotkb:CG33831(orf name)|uniprotkb:CG33837(orf name)|uniprotkb:CG33840(orf name)|uniprotkb:CG33843(orf name)|uniprotkb:CG33846(orf name)|uniprotkb:CG33849(orf name)|uniprotkb:CG33852(orf name)|uniprotkb:CG33864(orf name)|uniprotkb:"His1:CG33804"(gene name)|psi-mi:"His1:CG33804"(display_short)|uniprotkb:"His1:CG33810"(gene name)|psi-mi:"His1:CG33810"(display_short)|uniprotkb:"His1:CG33813"(gene name)|psi-mi:"His1:CG33813"(display_short)|uniprotkb:"His1:CG33816"(gene name)|psi-mi:"His1:CG33816"(display_short)|uniprotkb:"His1:CG33819"(gene name)|psi-mi:"His1:CG33819"(display_short)|uniprotkb:"His1:CG33822"(gene name)|psi-mi:"His1:CG33822"(display_short)|uniprotkb:"His1:CG33825"(gene name)|psi-mi:"His1:CG33825"(display_short)|uniprotkb:"His1:CG33828"(gene name)|psi-mi:"His1:CG33828"(display_short)|uniprotkb:"His1:CG33831"(gene name)|psi-mi:"His1:CG33831"(display_short)|uniprotkb:"His1:CG33837"(gene name)|psi-mi:"His1:CG33837"(display_short)|uniprotkb:"His1:CG33840"(gene name)|psi-mi:"His1:CG33840"(display_short)|uniprotkb:"His1:CG33843"(gene name)|psi-mi:"His1:CG33843"(display_short) psi-mi:taf1_drome(display_long)|uniprotkb:Transcription initiation factor TFIID 230 kDa subunit(gene name synonym)|uniprotkb:TAFII250(gene name synonym)|uniprotkb:TBP-associated factor 230 kDa(gene name synonym)|uniprotkb:Taf1(gene name)|psi-mi:Taf1(display_short)|uniprotkb:TAF250(gene name synonym)|uniprotkb:CG17603(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873142 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027286.1|refseq:NP_001027295.1|refseq:NP_001027299.1|refseq:NP_001027304.1|refseq:NP_001027309.1|refseq:NP_001027314.1|refseq:NP_001027319.1|refseq:NP_001027324.1|refseq:NP_001027329.1|refseq:NP_001027339.1|refseq:NP_001027344.1|refseq:NP_001027349.1|refseq:NP_001027354.1|refseq:NP_001027359.1|refseq:NP_001027364.1|refseq:NP_001027384.1|refseq:NP_724341.1|flybase:FBgn0001195|flybase:FBgn0051617|flybase:FBgn0053804|flybase:FBgn0053810|flybase:FBgn0053813|flybase:FBgn0053816|flybase:FBgn0053819|flybase:FBgn0053822|flybase:FBgn0053825|flybase:FBgn0053828|flybase:FBgn0053831|flybase:FBgn0053837|flybase:FBgn0053840|flybase:FBgn0053843|flybase:FBgn0053846|flybase:FBgn0053849|flybase:FBgn0053852|flybase:FBgn0053864|dip:DIP-61415N|ensemblmetazoa:FBgn0051617(gene)|ensemblmetazoa:FBgn0053804(gene)|ensemblmetazoa:FBgn0053810(gene)|ensemblmetazoa:FBgn0053813(gene)|ensemblmetazoa:FBgn0053816(gene)|ensemblmetazoa:FBgn0053819(gene)|ensemblmetazoa:FBgn0053822(gene)|ensemblmetazoa:FBgn0053825(gene)|ensemblmetazoa:FBgn0053828(gene)|ensemblmetazoa:FBgn0053831(gene)|ensemblmetazoa:FBgn0053837(gene)|ensemblmetazoa:FBgn0053840(gene)|ensemblmetazoa:FBgn0053843(gene)|ensemblmetazoa:FBgn0053846(gene)|ensemblmetazoa:FBgn0053849(gene)|ensemblmetazoa:FBgn0053852(gene)|ensemblmetazoa:FBgn0053864(gene)|ensemblmetazoa:FBtr0085892(transcript)|ensemblmetazoa:FBtr0091808(transcript)|ensemblmetazoa:FBtr0091814(transcript)|ensemblmetazoa:FBtr0091817(transcript)|ensemblmetazoa:FBtr0091820(transcript)|ensemblmetazoa:FBtr0091823(transcript)|ensemblmetazoa:FBtr0091826(transcript)|ensemblmetazoa:FBtr0091829(transcript)|ensemblmetazoa:FBtr0091832(transcript)|ensemblmetazoa:FBtr0091835(transcript)|ensemblmetazoa:FBtr0091841(transcript)|ensemblmetazoa:FBtr0091844(transcript)|ensemblmetazoa:FBtr0091847(transcript)|ensemblmetazoa:FBtr0091850(transcript)|ensemblmetazoa:FBtr0091853(transcript)|ensemblmetazoa:FBtr0091856(transcript)|ensemblmetazoa:FBtr0091868(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031057"(negative regulation of histone modification)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051276"(chromosome organization)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390 refseq:NP_476956.3|refseq:NP_996159.1|refseq:NP_996160.1|flybase:FBgn0010355|dip:DIP-228N|ensemblmetazoa:FBgn0010355(gene)|ensemblmetazoa:FBtr0081685(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036408"("histone acetyltransferase activity (H3-K14 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR017956|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|rcsb pdb:1TBA|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 pubmed:11009423(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:OnsvMISg2QzGh1q182URqoXbpIY7227 rogid:DxUDrj8iljY131pQOBswejQxoxI7227 intact-crc:7F80C0AA01D83A72|rigid:m13o4LJpzurPfdvr2fsXyDFwhk8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q05783 uniprotkb:P02255 intact:EBI-171019|uniprotkb:Q540Z0|uniprotkb:Q9W2D3|ensemblmetazoa:FBpp0071625|ensemblmetazoa:FBpp0071626|ensemblmetazoa:FBpp0290624|ensemblmetazoa:FBpp0311598 intact:EBI-151629|uniprotkb:Q4ABD3|ensemblmetazoa:FBpp0085248|ensemblmetazoa:FBpp0091052|ensemblmetazoa:FBpp0091057|ensemblmetazoa:FBpp0091059|ensemblmetazoa:FBpp0091062|ensemblmetazoa:FBpp0091065|ensemblmetazoa:FBpp0091068|ensemblmetazoa:FBpp0091071|ensemblmetazoa:FBpp0091074|ensemblmetazoa:FBpp0091077|ensemblmetazoa:FBpp0091083|ensemblmetazoa:FBpp0091086|ensemblmetazoa:FBpp0091089|ensemblmetazoa:FBpp0091092|ensemblmetazoa:FBpp0091095|ensemblmetazoa:FBpp0091098|ensemblmetazoa:FBpp0091110 psi-mi:hmgd_drome(display_long)|uniprotkb:HmgD(gene name)|psi-mi:HmgD(display_short)|uniprotkb:CG17950(orf name) psi-mi:h1_drome(display_long)|uniprotkb:His1(gene name)|psi-mi:His1(display_short)|uniprotkb:"His1:CG31617"(gene name)|psi-mi:"His1:CG31617"(display_short)|uniprotkb:"His1:CG33846"(gene name)|psi-mi:"His1:CG33846"(display_short)|uniprotkb:"His1:CG33849"(gene name)|psi-mi:"His1:CG33849"(display_short)|uniprotkb:"His1:CG33852"(gene name)|psi-mi:"His1:CG33852"(display_short)|uniprotkb:"His1:CG33864"(gene name)|psi-mi:"His1:CG33864"(display_short)|uniprotkb:CG31617(orf name)|uniprotkb:CG33804(orf name)|uniprotkb:CG33810(orf name)|uniprotkb:CG33813(orf name)|uniprotkb:CG33816(orf name)|uniprotkb:CG33819(orf name)|uniprotkb:CG33822(orf name)|uniprotkb:CG33825(orf name)|uniprotkb:CG33828(orf name)|uniprotkb:CG33831(orf name)|uniprotkb:CG33837(orf name)|uniprotkb:CG33840(orf name)|uniprotkb:CG33843(orf name)|uniprotkb:CG33846(orf name)|uniprotkb:CG33849(orf name)|uniprotkb:CG33852(orf name)|uniprotkb:CG33864(orf name)|uniprotkb:"His1:CG33804"(gene name)|psi-mi:"His1:CG33804"(display_short)|uniprotkb:"His1:CG33810"(gene name)|psi-mi:"His1:CG33810"(display_short)|uniprotkb:"His1:CG33813"(gene name)|psi-mi:"His1:CG33813"(display_short)|uniprotkb:"His1:CG33816"(gene name)|psi-mi:"His1:CG33816"(display_short)|uniprotkb:"His1:CG33819"(gene name)|psi-mi:"His1:CG33819"(display_short)|uniprotkb:"His1:CG33822"(gene name)|psi-mi:"His1:CG33822"(display_short)|uniprotkb:"His1:CG33825"(gene name)|psi-mi:"His1:CG33825"(display_short)|uniprotkb:"His1:CG33828"(gene name)|psi-mi:"His1:CG33828"(display_short)|uniprotkb:"His1:CG33831"(gene name)|psi-mi:"His1:CG33831"(display_short)|uniprotkb:"His1:CG33837"(gene name)|psi-mi:"His1:CG33837"(display_short)|uniprotkb:"His1:CG33840"(gene name)|psi-mi:"His1:CG33840"(display_short)|uniprotkb:"His1:CG33843"(gene name)|psi-mi:"His1:CG33843"(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001286696.1|refseq:NP_001163244.1|refseq:NP_726109.1|refseq:NP_726110.1|flybase:FBgn0004362|go:"GO:0008301"(DNA binding, bending)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|rcsb pdb:1E7J|rcsb pdb:1HMA|rcsb pdb:1QRV|rcsb pdb:3NM9|reactome:R-DME-140342|reactome:R-DME-5620971|reactome:R-DME-5686938|reactome:R-DME-6798695|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|ensemblmetazoa:FBgn0004362(gene)|ensemblmetazoa:FBtr0071708(transcript)|ensemblmetazoa:FBtr0071709(transcript)|ensemblmetazoa:FBtr0301410(transcript)|ensemblmetazoa:FBtr0345487(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|dip:DIP-22805N refseq:NP_001027286.1|refseq:NP_001027295.1|refseq:NP_001027299.1|refseq:NP_001027304.1|refseq:NP_001027309.1|refseq:NP_001027314.1|refseq:NP_001027319.1|refseq:NP_001027324.1|refseq:NP_001027329.1|refseq:NP_001027339.1|refseq:NP_001027344.1|refseq:NP_001027349.1|refseq:NP_001027354.1|refseq:NP_001027359.1|refseq:NP_001027364.1|refseq:NP_001027384.1|refseq:NP_724341.1|flybase:FBgn0001195|flybase:FBgn0051617|flybase:FBgn0053804|flybase:FBgn0053810|flybase:FBgn0053813|flybase:FBgn0053816|flybase:FBgn0053819|flybase:FBgn0053822|flybase:FBgn0053825|flybase:FBgn0053828|flybase:FBgn0053831|flybase:FBgn0053837|flybase:FBgn0053840|flybase:FBgn0053843|flybase:FBgn0053846|flybase:FBgn0053849|flybase:FBgn0053852|flybase:FBgn0053864|dip:DIP-61415N|ensemblmetazoa:FBgn0051617(gene)|ensemblmetazoa:FBgn0053804(gene)|ensemblmetazoa:FBgn0053810(gene)|ensemblmetazoa:FBgn0053813(gene)|ensemblmetazoa:FBgn0053816(gene)|ensemblmetazoa:FBgn0053819(gene)|ensemblmetazoa:FBgn0053822(gene)|ensemblmetazoa:FBgn0053825(gene)|ensemblmetazoa:FBgn0053828(gene)|ensemblmetazoa:FBgn0053831(gene)|ensemblmetazoa:FBgn0053837(gene)|ensemblmetazoa:FBgn0053840(gene)|ensemblmetazoa:FBgn0053843(gene)|ensemblmetazoa:FBgn0053846(gene)|ensemblmetazoa:FBgn0053849(gene)|ensemblmetazoa:FBgn0053852(gene)|ensemblmetazoa:FBgn0053864(gene)|ensemblmetazoa:FBtr0085892(transcript)|ensemblmetazoa:FBtr0091808(transcript)|ensemblmetazoa:FBtr0091814(transcript)|ensemblmetazoa:FBtr0091817(transcript)|ensemblmetazoa:FBtr0091820(transcript)|ensemblmetazoa:FBtr0091823(transcript)|ensemblmetazoa:FBtr0091826(transcript)|ensemblmetazoa:FBtr0091829(transcript)|ensemblmetazoa:FBtr0091832(transcript)|ensemblmetazoa:FBtr0091835(transcript)|ensemblmetazoa:FBtr0091841(transcript)|ensemblmetazoa:FBtr0091844(transcript)|ensemblmetazoa:FBtr0091847(transcript)|ensemblmetazoa:FBtr0091850(transcript)|ensemblmetazoa:FBtr0091853(transcript)|ensemblmetazoa:FBtr0091856(transcript)|ensemblmetazoa:FBtr0091868(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031057"(negative regulation of histone modification)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051276"(chromosome organization)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390 pubmed:11473125(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:bKMoyFB0GkI5U328cR9LYEYThq47227 rogid:OnsvMISg2QzGh1q182URqoXbpIY7227 intact-crc:8282A2D844241DB8|rigid:SV/Os5AAHLRVT2J0J3o+5M/evSg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24150 uniprotkb:P84051 intact:EBI-603430 intact:EBI-182580|uniprotkb:P02267|uniprotkb:Q4ABC7|intact:EBI-9918571|ensemblmetazoa:FBpp0085249|ensemblmetazoa:FBpp0091055|ensemblmetazoa:FBpp0091060|ensemblmetazoa:FBpp0091063|ensemblmetazoa:FBpp0091066|ensemblmetazoa:FBpp0091069|ensemblmetazoa:FBpp0091072|ensemblmetazoa:FBpp0091075|ensemblmetazoa:FBpp0091078|ensemblmetazoa:FBpp0091081|ensemblmetazoa:FBpp0091084|ensemblmetazoa:FBpp0091087|ensemblmetazoa:FBpp0091090|ensemblmetazoa:FBpp0091093|ensemblmetazoa:FBpp0091096|ensemblmetazoa:FBpp0091108|ensemblmetazoa:FBpp0091111 psi-mi:q24150_drome(display_long)|uniprotkb:Nap1(gene name)|psi-mi:Nap1(display_short)|uniprotkb:CG5330(orf name) psi-mi:h2a_drome(display_long)|uniprotkb:His2A(gene name)|psi-mi:His2A(display_short)|uniprotkb:H2a(gene name synonym)|uniprotkb:"His2A:CG31618"(gene name)|psi-mi:"His2A:CG31618"(display_short)|uniprotkb:CG31618(orf name)|uniprotkb:"His2A:CG33808"(gene name)|psi-mi:"His2A:CG33808"(display_short)|uniprotkb:"His2A:CG33814"(gene name)|psi-mi:"His2A:CG33814"(display_short)|uniprotkb:"His2A:CG33817"(gene name)|psi-mi:"His2A:CG33817"(display_short)|uniprotkb:"His2A:CG33820"(gene name)|psi-mi:"His2A:CG33820"(display_short)|uniprotkb:"His2A:CG33823"(gene name)|psi-mi:"His2A:CG33823"(display_short)|uniprotkb:"His2A:CG33826"(gene name)|psi-mi:"His2A:CG33826"(display_short)|uniprotkb:"His2A:CG33829"(gene name)|psi-mi:"His2A:CG33829"(display_short)|uniprotkb:"His2A:CG33832"(gene name)|psi-mi:"His2A:CG33832"(display_short)|uniprotkb:"His2A:CG33835"(gene name)|psi-mi:"His2A:CG33835"(display_short)|uniprotkb:"His2A:CG33838"(gene name)|psi-mi:"His2A:CG33838"(display_short)|uniprotkb:"His2A:CG33841"(gene name)|psi-mi:"His2A:CG33841"(display_short)|uniprotkb:"His2A:CG33844"(gene name)|psi-mi:"His2A:CG33844"(display_short)|uniprotkb:"His2A:CG33847"(gene name)|psi-mi:"His2A:CG33847"(display_short)|uniprotkb:"His2A:CG33850"(gene name)|psi-mi:"His2A:CG33850"(display_short)|uniprotkb:"His2A:CG33862"(gene name)|psi-mi:"His2A:CG33862"(display_short)|uniprotkb:"His2A:CG33865"(gene name)|psi-mi:"His2A:CG33865"(display_short)|uniprotkb:CG33808(orf name)|uniprotkb:CG33814(orf name)|uniprotkb:CG33817(orf name)|uniprotkb:CG33820(orf name)|uniprotkb:CG33823(orf name)|uniprotkb:CG33826(orf name)|uniprotkb:CG33829(orf name)|uniprotkb:CG33832(orf name)|uniprotkb:CG33835(orf name)|uniprotkb:CG33838(orf name)|uniprotkb:CG33841(orf name)|uniprotkb:CG33844(orf name)|uniprotkb:CG33847(orf name)|uniprotkb:CG33850(orf name)|uniprotkb:CG33862(orf name)|uniprotkb:CG33865(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000723"(telomere maintenance)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0035041"(sperm DNA decondensation)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|flybase:FBgn0015268 refseq:NP_001027292.1|refseq:NP_001027301.1|refseq:NP_001027306.1|refseq:NP_001027311.1|refseq:NP_001027316.1|refseq:NP_001027321.1|refseq:NP_001027326.1|refseq:NP_001027331.1|refseq:NP_001027336.1|refseq:NP_001027341.1|refseq:NP_001027346.1|refseq:NP_001027351.1|refseq:NP_001027356.1|refseq:NP_001027361.1|refseq:NP_001027381.1|refseq:NP_001027386.1|refseq:NP_724343.1|flybase:FBgn0001196|flybase:FBgn0051618|flybase:FBgn0053808|flybase:FBgn0053814|flybase:FBgn0053817|flybase:FBgn0053820|flybase:FBgn0053823|flybase:FBgn0053826|flybase:FBgn0053829|flybase:FBgn0053832|flybase:FBgn0053835|flybase:FBgn0053838|flybase:FBgn0053841|flybase:FBgn0053844|flybase:FBgn0053847|flybase:FBgn0053850|flybase:FBgn0053862|flybase:FBgn0053865|dip:DIP-29504N|ensemblmetazoa:FBgn0051618(gene)|ensemblmetazoa:FBgn0053808(gene)|ensemblmetazoa:FBgn0053814(gene)|ensemblmetazoa:FBgn0053817(gene)|ensemblmetazoa:FBgn0053820(gene)|ensemblmetazoa:FBgn0053823(gene)|ensemblmetazoa:FBgn0053826(gene)|ensemblmetazoa:FBgn0053829(gene)|ensemblmetazoa:FBgn0053832(gene)|ensemblmetazoa:FBgn0053835(gene)|ensemblmetazoa:FBgn0053838(gene)|ensemblmetazoa:FBgn0053841(gene)|ensemblmetazoa:FBgn0053844(gene)|ensemblmetazoa:FBgn0053847(gene)|ensemblmetazoa:FBgn0053850(gene)|ensemblmetazoa:FBgn0053862(gene)|ensemblmetazoa:FBgn0053865(gene)|ensemblmetazoa:FBtr0085893(transcript)|ensemblmetazoa:FBtr0091812(transcript)|ensemblmetazoa:FBtr0091818(transcript)|ensemblmetazoa:FBtr0091821(transcript)|ensemblmetazoa:FBtr0091824(transcript)|ensemblmetazoa:FBtr0091827(transcript)|ensemblmetazoa:FBtr0091830(transcript)|ensemblmetazoa:FBtr0091833(transcript)|ensemblmetazoa:FBtr0091836(transcript)|ensemblmetazoa:FBtr0091839(transcript)|ensemblmetazoa:FBtr0091842(transcript)|ensemblmetazoa:FBtr0091845(transcript)|ensemblmetazoa:FBtr0091848(transcript)|ensemblmetazoa:FBtr0091851(transcript)|ensemblmetazoa:FBtr0091854(transcript)|ensemblmetazoa:FBtr0091866(transcript)|ensemblmetazoa:FBtr0091869(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:4QLC|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6DZT|rcsb pdb:6PWE|rcsb pdb:6PWF pubmed:8649423(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NvLzkn4vQ1SBJDrKk24AE4sFmrI7227 rogid:8z5Mv86au0E38ZhRr23yRgd4sEY7227 intact-crc:EEC7AF3D18A90E5D|rigid:0IaSI683Ka8RcnElgWJ+3r7GTm0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24150 uniprotkb:P02283 intact:EBI-603430 intact:EBI-188137|uniprotkb:Q4ABE1|uniprotkb:Q9W5U7|ensemblmetazoa:FBpp0085281|ensemblmetazoa:FBpp0091113|ensemblmetazoa:FBpp0091115|ensemblmetazoa:FBpp0091117|ensemblmetazoa:FBpp0091119|ensemblmetazoa:FBpp0091121|ensemblmetazoa:FBpp0091123|ensemblmetazoa:FBpp0091125|ensemblmetazoa:FBpp0091127|ensemblmetazoa:FBpp0091129|ensemblmetazoa:FBpp0091131|ensemblmetazoa:FBpp0091133|ensemblmetazoa:FBpp0091135|ensemblmetazoa:FBpp0091137|ensemblmetazoa:FBpp0091139|ensemblmetazoa:FBpp0091141|ensemblmetazoa:FBpp0091143|ensemblmetazoa:FBpp0091145|ensemblmetazoa:FBpp0091147|ensemblmetazoa:FBpp0091149|ensemblmetazoa:FBpp0091151|ensemblmetazoa:FBpp0091153|ensemblmetazoa:FBpp0091155 psi-mi:q24150_drome(display_long)|uniprotkb:Nap1(gene name)|psi-mi:Nap1(display_short)|uniprotkb:CG5330(orf name) psi-mi:h2b_drome(display_long)|uniprotkb:His2B(gene name)|psi-mi:His2B(display_short)|uniprotkb:"His2B:CG17949"(gene name)|psi-mi:"His2B:CG17949"(display_short)|uniprotkb:"His2B:CG33868"(gene name)|psi-mi:"His2B:CG33868"(display_short)|uniprotkb:"His2B:CG33870"(gene name)|psi-mi:"His2B:CG33870"(display_short)|uniprotkb:"His2B:CG33872"(gene name)|psi-mi:"His2B:CG33872"(display_short)|uniprotkb:"His2B:CG33874"(gene name)|psi-mi:"His2B:CG33874"(display_short)|uniprotkb:"His2B:CG33876"(gene name)|psi-mi:"His2B:CG33876"(display_short)|uniprotkb:"His2B:CG33878"(gene name)|psi-mi:"His2B:CG33878"(display_short)|uniprotkb:"His2B:CG33880"(gene name)|psi-mi:"His2B:CG33880"(display_short)|uniprotkb:"His2B:CG33882"(gene name)|psi-mi:"His2B:CG33882"(display_short)|uniprotkb:"His2B:CG33884"(gene name)|psi-mi:"His2B:CG33884"(display_short)|uniprotkb:"His2B:CG33886"(gene name)|psi-mi:"His2B:CG33886"(display_short)|uniprotkb:"His2B:CG33888"(gene name)|psi-mi:"His2B:CG33888"(display_short)|uniprotkb:"His2B:CG33890"(gene name)|psi-mi:"His2B:CG33890"(display_short)|uniprotkb:"His2B:CG33892"(gene name)|psi-mi:"His2B:CG33892"(display_short)|uniprotkb:"His2B:CG33894"(gene name)|psi-mi:"His2B:CG33894"(display_short)|uniprotkb:"His2B:CG33896"(gene name)|psi-mi:"His2B:CG33896"(display_short)|uniprotkb:"His2B:CG33898"(gene name)|psi-mi:"His2B:CG33898"(display_short)|uniprotkb:"His2B:CG33900"(gene name)|psi-mi:"His2B:CG33900"(display_short)|uniprotkb:"His2B:CG33902"(gene name)|psi-mi:"His2B:CG33902"(display_short)|uniprotkb:"His2B:CG33904"(gene name)|psi-mi:"His2B:CG33904"(display_short)|uniprotkb:"His2B:CG33906"(gene name)|psi-mi:"His2B:CG33906"(display_short)|uniprotkb:"His2B:CG33908"(gene name)|psi-mi:"His2B:CG33908"(display_short)|uniprotkb:"His2B:CG33910"(gene name)|psi-mi:"His2B:CG33910"(display_short)|uniprotkb:CG17949(orf name)|uniprotkb:CG33868(orf name)|uniprotkb:CG33870(orf name)|uniprotkb:CG33872(orf name)|uniprotkb:CG33874(orf name)|uniprotkb:CG33876(orf name)|uniprotkb:CG33878(orf name)|uniprotkb:CG33880(orf name)|uniprotkb:CG33882(orf name)|uniprotkb:CG33884(orf name)|uniprotkb:CG33886(orf name)|uniprotkb:CG33888(orf name)|uniprotkb:CG33890(orf name)|uniprotkb:CG33892(orf name)|uniprotkb:CG33894(orf name)|uniprotkb:CG33896(orf name)|uniprotkb:CG33898(orf name)|uniprotkb:CG33900(orf name)|uniprotkb:CG33902(orf name)|uniprotkb:CG33904(orf name)|uniprotkb:CG33906(orf name)|uniprotkb:CG33908(orf name)|uniprotkb:CG33910(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000723"(telomere maintenance)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0035041"(sperm DNA decondensation)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|flybase:FBgn0015268 refseq:NP_001027283.1|refseq:NP_001027287.1|refseq:NP_001027291.1|refseq:NP_001027296.1|refseq:NP_001027300.1|refseq:NP_001027305.1|refseq:NP_001027310.1|refseq:NP_001027315.1|refseq:NP_001027320.1|refseq:NP_001027325.1|refseq:NP_001027330.1|refseq:NP_001027335.1|refseq:NP_001027340.1|refseq:NP_001027345.1|refseq:NP_001027350.1|refseq:NP_001027355.1|refseq:NP_001027360.1|refseq:NP_001027365.1|refseq:NP_001027370.1|refseq:NP_001027375.1|refseq:NP_001027380.1|refseq:NP_001027385.1|refseq:NP_724342.1|flybase:FBgn0001198|flybase:FBgn0061209|flybase:FBgn0053868|flybase:FBgn0053870|flybase:FBgn0053872|flybase:FBgn0053874|flybase:FBgn0053876|flybase:FBgn0053878|flybase:FBgn0053880|flybase:FBgn0053882|flybase:FBgn0053884|flybase:FBgn0053886|flybase:FBgn0053888|flybase:FBgn0053890|flybase:FBgn0053892|flybase:FBgn0053894|flybase:FBgn0053896|flybase:FBgn0053898|flybase:FBgn0053900|flybase:FBgn0053902|flybase:FBgn0053904|flybase:FBgn0053906|flybase:FBgn0053908|flybase:FBgn0053910|dip:DIP-22804N|ensemblmetazoa:FBgn0053886(gene)|ensemblmetazoa:FBgn0053888(gene)|ensemblmetazoa:FBgn0053890(gene)|ensemblmetazoa:FBgn0053892(gene)|ensemblmetazoa:FBgn0053894(gene)|ensemblmetazoa:FBgn0053896(gene)|ensemblmetazoa:FBgn0053898(gene)|ensemblmetazoa:FBgn0053900(gene)|ensemblmetazoa:FBgn0053902(gene)|ensemblmetazoa:FBgn0053904(gene)|ensemblmetazoa:FBgn0053906(gene)|ensemblmetazoa:FBgn0053908(gene)|ensemblmetazoa:FBgn0053910(gene)|ensemblmetazoa:FBgn0061209(gene)|ensemblmetazoa:FBtr0085927(transcript)|ensemblmetazoa:FBtr0091872(transcript)|ensemblmetazoa:FBtr0091874(transcript)|ensemblmetazoa:FBtr0091876(transcript)|ensemblmetazoa:FBtr0091878(transcript)|ensemblmetazoa:FBtr0091880(transcript)|ensemblmetazoa:FBtr0091882(transcript)|ensemblmetazoa:FBtr0091884(transcript)|ensemblmetazoa:FBtr0091886(transcript)|ensemblmetazoa:FBtr0091888(transcript)|ensemblmetazoa:FBtr0091890(transcript)|ensemblmetazoa:FBtr0091892(transcript)|ensemblmetazoa:FBtr0091894(transcript)|ensemblmetazoa:FBtr0091896(transcript)|ensemblmetazoa:FBtr0091898(transcript)|ensemblmetazoa:FBtr0091900(transcript)|ensemblmetazoa:FBtr0091902(transcript)|ensemblmetazoa:FBtr0091904(transcript)|ensemblmetazoa:FBtr0091906(transcript)|ensemblmetazoa:FBtr0091908(transcript)|ensemblmetazoa:FBtr0091910(transcript)|ensemblmetazoa:FBtr0091912(transcript)|ensemblmetazoa:FBtr0091914(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02283|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:4QLC|rcsb pdb:4X23|rcsb pdb:5CVE|rcsb pdb:5WCU|rcsb pdb:6DZT|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-3214847|reactome:R-DME-5689880|reactome:R-DME-8866654|reactome:R-DME-8936459|ensemblmetazoa:FBgn0053868(gene)|ensemblmetazoa:FBgn0053870(gene)|ensemblmetazoa:FBgn0053872(gene)|ensemblmetazoa:FBgn0053874(gene)|ensemblmetazoa:FBgn0053876(gene)|ensemblmetazoa:FBgn0053878(gene)|ensemblmetazoa:FBgn0053880(gene)|ensemblmetazoa:FBgn0053882(gene)|ensemblmetazoa:FBgn0053884(gene) pubmed:8649423(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NvLzkn4vQ1SBJDrKk24AE4sFmrI7227 rogid:KuGc2Ovj9eNDpjfoKjx7mAA/g+E7227 intact-crc:942FD0A19F6769C7|rigid:mrGLw7tTGfArwPSfdhC4jZIBZYE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20659 uniprotkb:P02299 intact:EBI-591327|ensemblmetazoa:FBpp0082406|ensemblmetazoa:FBpp0082409|uniprotkb:Q27255|uniprotkb:Q27327|uniprotkb:Q8INF9|uniprotkb:Q960R2|uniprotkb:Q9VFL1|uniprotkb:A4V2V9|uniprotkb:A4V2W0|intact:EBI-3404288|intact:EBI-3417031|intact:EBI-9922180|intact:EBI-9933604 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 psi-mi:trx_drome(display_long)|uniprotkb:KMT2A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2A(gene name synonym)|uniprotkb:trx(gene name)|psi-mi:trx(display_short)|uniprotkb:CG8651(orf name)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873158 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0003862(gene)|ensemblmetazoa:FBtr0082947(transcript)|ensemblmetazoa:FBtr0082950(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|reactome:R-DME-8936459|reactome:R-DME-8939236|refseq:NP_001014621.1|refseq:NP_476769.1|refseq:NP_476770.1|refseq:NP_599108.1|refseq:NP_599109.1|flybase:FBgn0003862 refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231 pubmed:11544176(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:LDT4/pLaHAuL/kuZMReRH9ZDrNk7227 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 intact-crc:8A6AF178681023FF|rigid:OgYiskKdpkR6EGkaWsMIvOErFxk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8IRW8 uniprotkb:P02299 intact:EBI-168703|uniprotkb:O46083|uniprotkb:Q8MYR5|uniprotkb:Q8T9I7|intact:EBI-869738|uniprotkb:Q9W548|ensemblmetazoa:FBpp0070347 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 psi-mi:trr_drome(display_long)|uniprotkb:trr(gene name)|psi-mi:trr(display_short)|uniprotkb:KMT2C(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2C(gene name synonym)|uniprotkb:Trithorax-related protein(gene name synonym)|uniprotkb:CG3848(orf name) psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873162 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525040.2|refseq:NP_726773.2|flybase:FBgn0023518|ensemblmetazoa:FBgn0023518(gene)|ensemblmetazoa:FBtr0070363(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0007458"(progression of morphogenetic furrow involved in compound eye morphogenesis)|go:"GO:0016571"(histone methylation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|reactome:R-DME-201722|reactome:R-DME-8936459 refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231 pubmed:14603321(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:mvgI4Lvj+Pq+7/DPZ9bw69QNkug7227 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 intact-crc:E026BF47E51245BD|rigid:FnbWYBbDq14S7jlINFz30hqD4s4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P05205 uniprotkb:P02299 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873166 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231 pubmed:11859155(see-also)|pubmed:11566886(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 intact-crc:1392BCC2030DFA7B|rigid:2HyCrfd+te2vBnq6aEr3KWEfYCI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P26017 uniprotkb:P02299 intact:EBI-177152|uniprotkb:Q9VP49|ensemblmetazoa:FBpp0078059 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 psi-mi:pc_drome(display_long)|uniprotkb:Pc(gene name)|psi-mi:Pc(display_short)|uniprotkb:CG7618(orf name) psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873170 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524199.1|flybase:FBgn0003042|ensemblmetazoa:FBgn0003042(gene)|ensemblmetazoa:FBtr0078405(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007385"(specification of segmental identity, abdomen)|go:"GO:0007419"(ventral cord development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0022008"(neurogenesis)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042060"(wound healing)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|rcsb pdb:1PDQ|rcsb pdb:1PFB|reactome:R-DME-3108214|reactome:R-DME-3899300|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724 refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231 pubmed:12897052(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:EoeY3ywjOXNZO7fubeNPow+WW4w7227 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 intact-crc:5E72D2868ED73DA3|rigid:U9QCg5HjAmh9hRkvRrkvDSQmTiI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9V3I5 uniprotkb:P02299 intact:EBI-84939|uniprotkb:Q0E8F9|uniprotkb:Q95RY3|uniprotkb:B5RJL0|ensemblmetazoa:FBpp0075965|ensemblmetazoa:FBpp0075966|ensemblmetazoa:FBpp0304953|intact:EBI-3425957 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 psi-mi:jil1_drome(display_long)|uniprotkb:JIL-1(gene name)|psi-mi:JIL-1(display_short)|uniprotkb:CG6297(orf name) psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873174 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648432.1|refseq:NP_729661.1|flybase:FBgn0020412|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|ensemblmetazoa:FBgn0020412(gene)|ensemblmetazoa:FBtr0076236(transcript)|ensemblmetazoa:FBtr0076237(transcript)|go:"GO:0016456"(X chromosome located dosage compensation complex, transcription activating)|ensemblmetazoa:FBtr0332707(transcript)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035175"("histone kinase activity (H3-S10 specific)")|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0048477"(oogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0000723"(telomere maintenance)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|reactome:R-DME-198753|reactome:R-DME-199920|reactome:R-DME-375165|reactome:R-DME-5621575|refseq:NP_001261697.1 refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231 pubmed:11371341(see-also)|pubmed:10445035(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NrVAOLnNFXZIoU33rJh/iIiWKZ87227 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 intact-crc:F87BA9E0467B6524|rigid:ar3n4Ldct4y8gANKgXMJJHgiN8k false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O02193 uniprotkb:P84040 intact:EBI-138539|uniprotkb:Q9W463|uniprotkb:A8B845|uniprotkb:A8B850|uniprotkb:A8B854|uniprotkb:A8B859|uniprotkb:A8B879|uniprotkb:A8B889|uniprotkb:A8B895|uniprotkb:A8B8A1|uniprotkb:A8ILB7|uniprotkb:A8ILC1|uniprotkb:A8ILC8|uniprotkb:A8ILD1|uniprotkb:A8ILD6|uniprotkb:A8ILE1|uniprotkb:A8ILE5|ensemblmetazoa:FBpp0070794 intact:EBI-185028|uniprotkb:A4V2W8|uniprotkb:P02307|uniprotkb:Q4AB71|uniprotkb:Q4ABE0|uniprotkb:Q6AWN1|uniprotkb:Q9VFH7|ensemblmetazoa:FBpp0082421|ensemblmetazoa:FBpp0082422|ensemblmetazoa:FBpp0082423|ensemblmetazoa:FBpp0085280|ensemblmetazoa:FBpp0091116|ensemblmetazoa:FBpp0091118|ensemblmetazoa:FBpp0091120|ensemblmetazoa:FBpp0091128|ensemblmetazoa:FBpp0091130|ensemblmetazoa:FBpp0091132|ensemblmetazoa:FBpp0091134|ensemblmetazoa:FBpp0091136|ensemblmetazoa:FBpp0091138|ensemblmetazoa:FBpp0091140|ensemblmetazoa:FBpp0091142|ensemblmetazoa:FBpp0091144|ensemblmetazoa:FBpp0091146|ensemblmetazoa:FBpp0091148|ensemblmetazoa:FBpp0091150|ensemblmetazoa:FBpp0091152|ensemblmetazoa:FBpp0091154|ensemblmetazoa:FBpp0306146 psi-mi:mof_drome(display_long)|uniprotkb:mof(gene name)|psi-mi:mof(display_short)|uniprotkb:Histone acetyl transferase MOF(gene name synonym)|uniprotkb:CG3025(orf name) psi-mi:h4_drome(display_long)|uniprotkb:H4(gene name synonym)|uniprotkb:His4r(gene name)|psi-mi:His4r(display_short)|uniprotkb:H4r(gene name synonym)|uniprotkb:CG3379(orf name)|uniprotkb:"His4:CG31611"(gene name)|psi-mi:"His4:CG31611"(display_short)|uniprotkb:CG31611(orf name)|uniprotkb:His4(gene name)|psi-mi:His4(display_short)|uniprotkb:"His4:CG33869"(gene name)|psi-mi:"His4:CG33869"(display_short)|uniprotkb:"His4:CG33871"(gene name)|psi-mi:"His4:CG33871"(display_short)|uniprotkb:"His4:CG33873"(gene name)|psi-mi:"His4:CG33873"(display_short)|uniprotkb:"His4:CG33875"(gene name)|psi-mi:"His4:CG33875"(display_short)|uniprotkb:"His4:CG33877"(gene name)|psi-mi:"His4:CG33877"(display_short)|uniprotkb:"His4:CG33879"(gene name)|psi-mi:"His4:CG33879"(display_short)|uniprotkb:"His4:CG33881"(gene name)|psi-mi:"His4:CG33881"(display_short)|uniprotkb:"His4:CG33883"(gene name)|psi-mi:"His4:CG33883"(display_short)|uniprotkb:"His4:CG33885"(gene name)|psi-mi:"His4:CG33885"(display_short)|uniprotkb:"His4:CG33887"(gene name)|psi-mi:"His4:CG33887"(display_short)|uniprotkb:"His4:CG33889"(gene name)|psi-mi:"His4:CG33889"(display_short)|uniprotkb:"His4:CG33891"(gene name)|psi-mi:"His4:CG33891"(display_short)|uniprotkb:"His4:CG33893"(gene name)|psi-mi:"His4:CG33893"(display_short)|uniprotkb:"His4:CG33895"(gene name)|psi-mi:"His4:CG33895"(display_short)|uniprotkb:"His4:CG33897"(gene name)|psi-mi:"His4:CG33897"(display_short)|uniprotkb:"His4:CG33899"(gene name)|psi-mi:"His4:CG33899"(display_short)|uniprotkb:"His4:CG33901"(gene name)|psi-mi:"His4:CG33901"(display_short)|uniprotkb:"His4:CG33903"(gene name)|psi-mi:"His4:CG33903"(display_short)|uniprotkb:"His4:CG33905"(gene name)|psi-mi:"His4:CG33905"(display_short)|uniprotkb:"His4:CG33907"(gene name)|psi-mi:"His4:CG33907"(display_short)|uniprotkb:"His4:CG33909"(gene name)|psi-mi:"His4:CG33909"(display_short)|uniprotkb:CG33869(orf name)|uniprotkb:CG33871(orf name)|uniprotkb:CG33873(orf name)|uniprotkb:CG33875(orf name)|uniprotkb:CG33877(orf name)|uniprotkb:CG33879(orf name)|uniprotkb:CG33881(orf name)|uniprotkb:CG33883(orf name)|uniprotkb:CG33885(orf name)|uniprotkb:CG33887(orf name)|uniprotkb:CG33889(orf name)|uniprotkb:CG33891(orf name)|uniprotkb:CG33893(orf name)|uniprotkb:CG33895(orf name)|uniprotkb:CG33897(orf name)|uniprotkb:CG33899(orf name)|uniprotkb:CG33901(orf name)|uniprotkb:CG33903(orf name)|uniprotkb:CG33905(orf name)|uniprotkb:CG33907(orf name)|uniprotkb:CG33909(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873178 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000805"(X chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006281"(DNA repair)|go:"GO:0007549"(dosage compensation)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016456"(X chromosome located dosage compensation complex, transcription activating)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042393"(histone binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072487"(MSL complex)|go:"GO:2000873"(regulation of histone H4 acetylation involved in response to DNA damage stimulus)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037906|interpro:IPR040706|rcsb pdb:2BUD|ensemblmetazoa:FBgn0014340(gene)|ensemblmetazoa:FBtr0070829(transcript)|refseq:NP_511051.1|flybase:FBgn0014340|dip:DIP-46346N refseq:NP_001027357.1|refseq:NP_001027284.1|refseq:NP_001027288.1|refseq:NP_001027293.1|refseq:NP_001027297.1|refseq:NP_001027302.1|refseq:NP_001027307.1|refseq:NP_001027312.1|refseq:NP_001027317.1|refseq:NP_001027322.1|refseq:NP_001027327.1|refseq:NP_001027332.1|refseq:NP_001027337.1|refseq:NP_001027342.1|refseq:NP_001027347.1|refseq:NP_001027352.1|refseq:NP_001027362.1|refseq:NP_001027367.1|refseq:NP_001027372.1|refseq:NP_001027377.1|refseq:NP_001027382.1|refseq:NP_524352.1|refseq:NP_724344.1|refseq:NP_731927.1|refseq:NP_731928.1|flybase:FBgn0001200|flybase:FBgn0051611|flybase:FBgn0053869|flybase:FBgn0053871|flybase:FBgn0053873|flybase:FBgn0053875|flybase:FBgn0053877|flybase:FBgn0053879|flybase:FBgn0053881|flybase:FBgn0053883|flybase:FBgn0053885|flybase:FBgn0053887|flybase:FBgn0053889|flybase:FBgn0053891|flybase:FBgn0053893|flybase:FBgn0053895|flybase:FBgn0053897|flybase:FBgn0053899|flybase:FBgn0053901|flybase:FBgn0053903|flybase:FBgn0053905|flybase:FBgn0053907|flybase:FBgn0053909|flybase:FBgn0013981|refseq:NP_001262576.1|dip:DIP-29505N|ensemblmetazoa:FBgn0013981(gene)|ensemblmetazoa:FBgn0051611(gene)|ensemblmetazoa:FBgn0053871(gene)|ensemblmetazoa:FBgn0053873(gene)|ensemblmetazoa:FBgn0053875(gene)|ensemblmetazoa:FBgn0053883(gene)|ensemblmetazoa:FBgn0053885(gene)|ensemblmetazoa:FBgn0053887(gene)|ensemblmetazoa:FBgn0053889(gene)|ensemblmetazoa:FBgn0053891(gene)|ensemblmetazoa:FBgn0053893(gene)|ensemblmetazoa:FBgn0053895(gene)|ensemblmetazoa:FBgn0053897(gene)|ensemblmetazoa:FBgn0053899(gene)|ensemblmetazoa:FBgn0053901(gene)|ensemblmetazoa:FBgn0053903(gene)|ensemblmetazoa:FBgn0053905(gene)|ensemblmetazoa:FBgn0053907(gene)|ensemblmetazoa:FBgn0053909(gene)|ensemblmetazoa:FBtr0082962(transcript)|ensemblmetazoa:FBtr0082963(transcript)|ensemblmetazoa:FBtr0082964(transcript)|ensemblmetazoa:FBtr0085926(transcript)|ensemblmetazoa:FBtr0091875(transcript)|ensemblmetazoa:FBtr0091877(transcript)|ensemblmetazoa:FBtr0091879(transcript)|ensemblmetazoa:FBtr0091887(transcript)|ensemblmetazoa:FBtr0091889(transcript)|ensemblmetazoa:FBtr0091891(transcript)|ensemblmetazoa:FBtr0091893(transcript)|ensemblmetazoa:FBtr0091895(transcript)|ensemblmetazoa:FBtr0091897(transcript)|ensemblmetazoa:FBtr0091899(transcript)|ensemblmetazoa:FBtr0091901(transcript)|ensemblmetazoa:FBtr0091903(transcript)|ensemblmetazoa:FBtr0091905(transcript)|ensemblmetazoa:FBtr0091907(transcript)|ensemblmetazoa:FBtr0091909(transcript)|ensemblmetazoa:FBtr0091911(transcript)|ensemblmetazoa:FBtr0091913(transcript)|ensemblmetazoa:FBtr0334029(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|mint:P84040|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2XYI|rcsb pdb:3C9C|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6DZT|rcsb pdb:6PWE|rcsb pdb:6PWF|rcsb pdb:6XWS|rcsb pdb:6XWT pubmed:11258702(see-also)|pubmed:9155031(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:YoHi/N+rxfKrb2CV6iRu+e0BEvs7227 rogid:DcYNQkOFmB4Cq/YNNvGuibPk2MM7227 intact-crc:FB2031E6D3C89252|rigid:2BwnXokNgH10o8cqHsc5vrH+FTY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08510 uniprotkb:Q24052 intact:EBI-85074|uniprotkb:A4V4Q2|uniprotkb:P08511|uniprotkb:P08512|uniprotkb:P08513|uniprotkb:Q24277|uniprotkb:Q24521|uniprotkb:Q7KUW5|uniprotkb:Q8IQY9|uniprotkb:Q8MT41|uniprotkb:Q9VWZ5|uniprotkb:Q9VWZ9|uniprotkb:Q9VX00|ensemblmetazoa:FBpp0088599|uniprotkb:B6IDJ2|uniprotkb:M9MSC0|uniprotkb:M9NEM4|uniprotkb:M9PF21 intact:EBI-498048 psi-mi:kcnas_drome(display_long)|uniprotkb:Sh(gene name)|psi-mi:Sh(display_short)|uniprotkb:mns(gene name synonym)|uniprotkb:Protein minisleep(gene name synonym)|uniprotkb:CG12348(orf name) psi-mi:q24052_drome(display_long)|uniprotkb:Hk(gene name)|psi-mi:Hk(display_short)|uniprotkb:CG43388(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873182 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162788.1|refseq:NP_001188668.1|refseq:NP_523393.3|refseq:NP_728120.1|refseq:NP_728122.1|refseq:NP_728123.1|refseq:NP_728124.1|refseq:NP_996497.1|ensemblmetazoa:FBgn0003380(gene)|ensemblmetazoa:FBtr0089657(transcript)|go:"GO:0001508"(action potential)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007611"(learning or memory)|go:"GO:0007619"(courtship behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0009584"(detection of visible light)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030431"(sleep)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0048047"(mating behavior, sex discrimination)|go:"GO:0007637"(proboscis extension reflex)|go:"GO:0048150"(behavioral response to ether)|go:"GO:0048675"(axon extension)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060025"(regulation of synaptic activity)|go:"GO:0071805"(potassium ion transmembrane transport)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:1HO2|rcsb pdb:1HO7|reactome:R-DME-1296072|go:"GO:1903351"(cellular response to dopamine)|refseq:NP_001259665.2|refseq:NP_996498.2|flybase:FBgn0003380|refseq:NP_001245727.1|dip:DIP-41151N flybase:FBgn0263220|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0050802"(circadian sleep/wake cycle, sleep)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1903818"(positive regulation of voltage-gated potassium channel activity)|interpro:IPR005399(Potassium channel, voltage-dependent, beta subunit, KCNAB-related)|interpro:IPR005983(Potassium channel, voltage-dependent, beta subunit, KCNAB)|interpro:IPR023210|interpro:IPR036812 pubmed:9497369(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:fEBHWlsCdztu/LP5Ecu0vdPDEVQ7227 rogid:MnNQ2sop2YJt4GWP9KoJOPrwQXw7227 intact-crc:2A1FC6FBAA33A260|rigid:K05UkmXrEVuuGsbbYgY0vaD4yv0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q01068 uniprotkb:Q01068 intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332 intact:EBI-121622|intact:EBI-1639233|uniprotkb:Q5S455|uniprotkb:Q5S479|uniprotkb:Q5S4J9|ensemblmetazoa:FBpp0084332 psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name) psi-mi:esm3_drome(display_long)|uniprotkb:"E(spl)m3-HLH"(gene name)|psi-mi:"E(spl)m3-HLH"(display_short)|uniprotkb:HLH-m3(gene name synonym)|uniprotkb:HLHm3(gene name synonym)|uniprotkb:CG8346(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873190 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N refseq:NP_524509.2|flybase:FBgn0002609|ensemblmetazoa:FBgn0002609(gene)|ensemblmetazoa:FBtr0084958(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-356N pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227 rogid:vUARbH3KdgSIFXpoweFPo1Di0vk7227 intact-crc:681CD107B183843F|rigid:TzRJeDHWarXwAfWT8xy7hHIsfFY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P13096 uniprotkb:P10084 intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352 intact:EBI-174136|intact:EBI-1639078|uniprotkb:O76890|uniprotkb:Q4V705|ensemblmetazoa:FBpp0070072 psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name) psi-mi:ast4_drome(display_long)|uniprotkb:sc(gene name)|psi-mi:sc(display_short)|uniprotkb:T4(gene name synonym)|uniprotkb:Protein scute(gene name synonym)|uniprotkb:sis-b(gene name synonym)|uniprotkb:CG3827(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873194 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 refseq:NP_476803.1|flybase:FBgn0004170|dip:DIP-325N|ensemblmetazoa:FBgn0004170(gene)|ensemblmetazoa:FBtr0070073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638 pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227 rogid:WTTmp3SuZ10YiZMKYALr68UiRO07227 intact-crc:39AE9EE0C731D29A|rigid:4xInL2XtooN1t+so5B96MVsqXUI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q01071 uniprotkb:P13096 intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328 intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352 psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name) psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873202 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227 rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227 intact-crc:A0325FFEF1495C7A|rigid:Fh7DW6UeyuhD3rIaB/DW6mnfWYQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P13096 uniprotkb:P13097 intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352 intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334 psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name) psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873210 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227 rogid:ko+76awzLWRJNBn06B3PQZWBhf47227 intact-crc:79E00F2799B866B4|rigid:6Bt5tbfQyPg48Bb6QV6eivlENy8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P13097 uniprotkb:P10084 intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334 intact:EBI-174136|intact:EBI-1639078|uniprotkb:O76890|uniprotkb:Q4V705|ensemblmetazoa:FBpp0070072 psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name) psi-mi:ast4_drome(display_long)|uniprotkb:sc(gene name)|psi-mi:sc(display_short)|uniprotkb:T4(gene name synonym)|uniprotkb:Protein scute(gene name synonym)|uniprotkb:sis-b(gene name synonym)|uniprotkb:CG3827(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873214 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638 refseq:NP_476803.1|flybase:FBgn0004170|dip:DIP-325N|ensemblmetazoa:FBgn0004170(gene)|ensemblmetazoa:FBtr0070073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638 pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ko+76awzLWRJNBn06B3PQZWBhf47227 rogid:WTTmp3SuZ10YiZMKYALr68UiRO07227 intact-crc:2DBF9EE0DC4012F1|rigid:YW33YvssDEHvawZNQpYRD92ldcI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q01069 uniprotkb:Q01069 intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355 intact:EBI-94554|intact:EBI-1639063|uniprotkb:Q01906|uniprotkb:Q540X9|uniprotkb:Q5S4K3|uniprotkb:Q9VBJ0|ensemblmetazoa:FBpp0084355 psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym) psi-mi:esmb_drome(display_long)|uniprotkb:"E(spl)mbeta-HLH"(gene name)|psi-mi:"E(spl)mbeta-HLH"(display_short)|uniprotkb:HLH-mbeta(gene name synonym)|uniprotkb:HLHmbeta(gene name synonym)|uniprotkb:CG14548(orf name)|uniprotkb:Split locus enhancer protein mA(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873218 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N refseq:NP_524505.2|flybase:FBgn0002733|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblmetazoa:FBgn0002733(gene)|ensemblmetazoa:FBtr0084982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|dip:DIP-721N pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227 rogid:pM6tCso2Uae9b5jO9YmXA8wEAPU7227 intact-crc:0C0DBD1A06825504|rigid:0sYxSim3vF/wf1PUgcskMqoCN08 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q01071 uniprotkb:Q01071 intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328 intact:EBI-118907|intact:EBI-1639272|uniprotkb:Q01897|uniprotkb:Q4V723|uniprotkb:Q56MT6|uniprotkb:Q56MU1|uniprotkb:Q56MU3|uniprotkb:Q56MU4|uniprotkb:Q56MU6|uniprotkb:Q56MU8|uniprotkb:Q56MV0|uniprotkb:Q56MV5|uniprotkb:Q56MV6|uniprotkb:Q56MW2|uniprotkb:Q56MW7|uniprotkb:Q56MW9|uniprotkb:Q56MX9|uniprotkb:Q56MY0|uniprotkb:Q56MY1|uniprotkb:Q56N19|uniprotkb:Q56N23|uniprotkb:Q5S485|uniprotkb:Q5S4A9|uniprotkb:Q5S4K5|ensemblmetazoa:FBpp0084328 psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name) psi-mi:esmd_drome(display_long)|uniprotkb:"E(spl)mdelta-HLH"(gene name)|psi-mi:"E(spl)mdelta-HLH"(display_short)|uniprotkb:HLH-mdelta(gene name synonym)|uniprotkb:HLHmdelta(gene name synonym)|uniprotkb:Split locus enhancer protein mC(gene name synonym)|uniprotkb:CG8328(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873222 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N refseq:NP_524503.2|flybase:FBgn0002734|ensemblmetazoa:FBgn0002734(gene)|ensemblmetazoa:FBtr0084954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|dip:DIP-722N pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227 rogid:Hj3BDiIsdTKnoVKAGru7+hHFLq47227 intact-crc:6EB2CC9BA33BDD0F|rigid:+NIRqitz5D9QPwlAbqX2u0SXDpc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24151 uniprotkb:Q24592 intact:EBI-254777|uniprotkb:Q0KI43|uniprotkb:Q24181|uniprotkb:Q59DV7|uniprotkb:Q5BIB0|uniprotkb:Q8IN54|uniprotkb:Q8SX55|uniprotkb:Q9VDL8|ensemblmetazoa:FBpp0088489|ensemblmetazoa:FBpp0306653 intact:EBI-521224|uniprotkb:Q712V3|uniprotkb:Q8SZI9|uniprotkb:Q9VYZ7|ensemblmetazoa:FBpp0073313 psi-mi:stat_drome(display_long)|uniprotkb:Stat92E(gene name)|psi-mi:Stat92E(display_short)|uniprotkb:MARE(gene name synonym)|uniprotkb:Stat(gene name synonym)|uniprotkb:mrL(gene name synonym)|uniprotkb:CG4257(orf name)|uniprotkb:Protein marelle(gene name synonym) psi-mi:jak_drome(display_long)|uniprotkb:hop(gene name)|psi-mi:hop(display_short)|uniprotkb:HD-160(gene name synonym)|uniprotkb:CG1594(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873226 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014643.1|refseq:NP_732516.2|refseq:NP_732517.2|refseq:NP_996242.1|refseq:NP_996243.1|flybase:FBgn0016917|refseq:NP_001262757.1|refseq:NP_001262762.1|dip:DIP-29510N|ensemblmetazoa:FBgn0016917(gene)|ensemblmetazoa:FBtr0089486(transcript)|ensemblmetazoa:FBtr0334586(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007379"(segment specification)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007538"(primary sex determination)|go:"GO:0007616"(long-term memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008348"(negative regulation of antimicrobial humoral response)|go:"GO:0017145"(stem cell division)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042393"(histone binding)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR036535|interpro:IPR036860|reactome:R-DME-1059683|reactome:R-DME-1251985|reactome:R-DME-1433557|reactome:R-DME-186763|reactome:R-DME-209228|reactome:R-DME-209394|reactome:R-DME-209405|reactome:R-DME-210671|reactome:R-DME-210688|reactome:R-DME-210693|reactome:R-DME-3249367|reactome:R-DME-6783783|reactome:R-DME-6785807|reactome:R-DME-877300|reactome:R-DME-877312|reactome:R-DME-8854691|reactome:R-DME-8983432|reactome:R-DME-8984722|reactome:R-DME-8985947|reactome:R-DME-9008059|reactome:R-DME-9020591|reactome:R-DME-9020933|reactome:R-DME-9020956|reactome:R-DME-909733 refseq:NP_511119.2|flybase:FBgn0004864|dip:DIP-61595N|ensemblmetazoa:FBgn0004864(gene)|ensemblmetazoa:FBtr0073457(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007365"(periodic partitioning)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0007481"(haltere disc morphogenesis)|go:"GO:0007538"(primary sex determination)|go:"GO:0007616"(long-term memory)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0042386"(hemocyte differentiation)|go:"GO:0045317"(equator specification)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0048749"(compound eye development)|go:"GO:0051607"(defense response to virus)|go:"GO:0060031"(mediolateral intercalation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR036860|reactome:R-DME-1266695|reactome:R-DME-1433557|reactome:R-DME-209209|reactome:R-DME-209228|reactome:R-DME-210688|reactome:R-DME-5673000|reactome:R-DME-6785807|reactome:R-DME-69231|reactome:R-DME-8985947|reactome:R-DME-9020558|reactome:R-DME-9027276|reactome:R-DME-9027284 pubmed:8608595(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:sAAgBR+DCg0o/jzk+KFV/ZH6aMU7227 rogid:3LpEsspOZyEaY6hDP/uKjAlBqZo7227 intact-crc:7158E1D6E592BE84|rigid:jG60tQhxpxN8+dr08DdAAIzXG9A false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P11346 uniprotkb:Q24592 intact:EBI-664624|uniprotkb:Q9W4Z3|uniprotkb:Q8I086|uniprotkb:Q8I0D9|uniprotkb:Q8ISE1|uniprotkb:Q8ISE2|uniprotkb:Q8ISE3|uniprotkb:Q9NEH9|uniprotkb:A8JUV5|uniprotkb:Q0KHW7|ensemblmetazoa:FBpp0070385|ensemblmetazoa:FBpp0310458 intact:EBI-521224|uniprotkb:Q712V3|uniprotkb:Q8SZI9|uniprotkb:Q9VYZ7|ensemblmetazoa:FBpp0073313 psi-mi:kraf1_drome(display_long)|uniprotkb:Raf(gene name)|psi-mi:Raf(display_short)|uniprotkb:Protein pole-hole(gene name synonym)|uniprotkb:ph(gene name synonym)|uniprotkb:phl(gene name synonym)|uniprotkb:CG2845(orf name) psi-mi:jak_drome(display_long)|uniprotkb:hop(gene name)|psi-mi:hop(display_short)|uniprotkb:HD-160(gene name synonym)|uniprotkb:CG1594(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873230 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525047.1|flybase:FBgn0003079|refseq:NP_001096867.3|dip:DIP-29769N|ensemblmetazoa:FBgn0003079(gene)|ensemblmetazoa:FBtr0070401(transcript)|ensemblmetazoa:FBtr0344007(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0002168"(instar larval development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007552"(metamorphosis)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042386"(hemocyte differentiation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029071|reactome:R-DME-1295596|reactome:R-DME-170968|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-432553|reactome:R-DME-5621575|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5675482 refseq:NP_511119.2|flybase:FBgn0004864|dip:DIP-61595N|ensemblmetazoa:FBgn0004864(gene)|ensemblmetazoa:FBtr0073457(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007365"(periodic partitioning)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0007481"(haltere disc morphogenesis)|go:"GO:0007538"(primary sex determination)|go:"GO:0007616"(long-term memory)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0042386"(hemocyte differentiation)|go:"GO:0045317"(equator specification)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0048749"(compound eye development)|go:"GO:0051607"(defense response to virus)|go:"GO:0060031"(mediolateral intercalation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR036860|reactome:R-DME-1266695|reactome:R-DME-1433557|reactome:R-DME-209209|reactome:R-DME-209228|reactome:R-DME-210688|reactome:R-DME-5673000|reactome:R-DME-6785807|reactome:R-DME-69231|reactome:R-DME-8985947|reactome:R-DME-9020558|reactome:R-DME-9027276|reactome:R-DME-9027284 pubmed:11919715(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:rbvsd7+5RvYrFoXyonEM6Li84hM7227 rogid:3LpEsspOZyEaY6hDP/uKjAlBqZo7227 intact-crc:A8C0F10933F93F93|rigid:vNmx3EYz3K6ZksfwRZrvDFfFNHc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24306 uniprotkb:Q8T0S6 intact:EBI-456419|uniprotkb:A4V1Z9|uniprotkb:Q0E8E4|uniprotkb:Q8MRM5|uniprotkb:Q9VUX5|uniprotkb:A9UN33|ensemblmetazoa:FBpp0075254|ensemblmetazoa:FBpp0075255|ensemblmetazoa:FBpp0075256|ensemblmetazoa:FBpp0305793|ensemblmetazoa:FBpp0305794|ensemblmetazoa:FBpp0305795 intact:EBI-101858|uniprotkb:Q9V8W4|ensemblmetazoa:FBpp0085688|ensemblmetazoa:FBpp0304253 psi-mi:diap1_drome(display_long)|uniprotkb:Diap1(gene name)|psi-mi:Diap1(display_short)|uniprotkb:Apoptosis 1 inhibitor(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase th(gene name synonym)|uniprotkb:Iap1(gene name synonym)|uniprotkb:Inhibitor of apoptosis 1(gene name synonym)|uniprotkb:Protein thread(gene name synonym)|uniprotkb:th(gene name synonym)|uniprotkb:CG12284(orf name)|uniprotkb:RING-type E3 ubiquitin transferase Diap1(gene name synonym) psi-mi:hippo_drome(display_long)|uniprotkb:hpo(gene name)|psi-mi:hpo(display_short)|uniprotkb:dMST(gene name synonym)|uniprotkb:Drosophila homolog of MST1 and MST2(gene name synonym)|uniprotkb:STE20-like kinase MST(gene name synonym)|uniprotkb:CG11228(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873234 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524101.2|refseq:NP_730097.1|refseq:NP_730098.1|flybase:FBgn0260635|refseq:NP_001261916.1|refseq:NP_001261917.1|refseq:NP_001261918.1|go:"GO:0006915"(apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0022416"(chaeta development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0045116"(protein neddylation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|ensemblmetazoa:FBgn0260635(gene)|ensemblmetazoa:FBtr0075499(transcript)|ensemblmetazoa:FBtr0075500(transcript)|ensemblmetazoa:FBtr0075501(transcript)|ensemblmetazoa:FBtr0333617(transcript)|ensemblmetazoa:FBtr0333618(transcript)|ensemblmetazoa:FBtr0333619(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|mint:Q24306|rcsb pdb:1JD4|rcsb pdb:1JD5|rcsb pdb:1JD6|rcsb pdb:1Q4Q|rcsb pdb:1SDZ|rcsb pdb:1SE0|rcsb pdb:3SIP|rcsb pdb:3SIQ|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-3769402|reactome:R-DME-390150|reactome:R-DME-5675482|reactome:R-DME-8948747|reactome:R-DME-8948751 interpro:IPR036674|mint:Q8T0S6|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-451806|interpro:IPR024205|refseq:NP_611427.1|flybase:FBgn0261456|ensemblmetazoa:FBgn0261456(gene)|ensemblmetazoa:FBtr0086500(transcript)|ensemblmetazoa:FBtr0331920(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0042127"(regulation of cell population proliferation)|refseq:NP_001261092.1|dip:DIP-17921N pubmed:14502295(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:loBQ//cKQ1NYhq3gnIKwRBn5vZg7227 rogid:KpEHzTCz7M84Nh6cjyyS55/p+XE7227 intact-crc:F33AC10B90B84CDE|rigid:aFZ/zuSmmnlE8Y+s2BvMskusGs0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VCR6 uniprotkb:Q8T0S6 intact:EBI-145004|uniprotkb:Q8MQH6|uniprotkb:Q8T9A6|uniprotkb:Q9VCR5|ensemblmetazoa:FBpp0083749 intact:EBI-101858|uniprotkb:Q9V8W4|ensemblmetazoa:FBpp0085688|ensemblmetazoa:FBpp0304253 psi-mi:sav_drome(display_long)|uniprotkb:sav(gene name)|psi-mi:sav(display_short)|uniprotkb:SHRP(gene name synonym)|uniprotkb:CG33193(orf name)|uniprotkb:Shar-pei(gene name synonym) psi-mi:hippo_drome(display_long)|uniprotkb:hpo(gene name)|psi-mi:hpo(display_short)|uniprotkb:dMST(gene name synonym)|uniprotkb:Drosophila homolog of MST1 and MST2(gene name synonym)|uniprotkb:STE20-like kinase MST(gene name synonym)|uniprotkb:CG11228(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873238 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_788721.1|flybase:FBgn0053193|dip:DIP-18696N|ensemblmetazoa:FBgn0053193(gene)|ensemblmetazoa:FBtr0084356(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007444"(imaginal disc development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0035329"(hippo signaling)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072002"(Malpighian tubule development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0106037"(apicomedial cortex)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR011524(SARAH)|interpro:IPR030030|interpro:IPR036020|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150 interpro:IPR036674|mint:Q8T0S6|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-451806|interpro:IPR024205|refseq:NP_611427.1|flybase:FBgn0261456|ensemblmetazoa:FBgn0261456(gene)|ensemblmetazoa:FBtr0086500(transcript)|ensemblmetazoa:FBtr0331920(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0042127"(regulation of cell population proliferation)|refseq:NP_001261092.1|dip:DIP-17921N pubmed:14502294(see-also)|pubmed:14502295(see-also)|pubmed:12941273(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:/omCdWbZCQT01Iwj5eU7isz1Kr47227 rogid:KpEHzTCz7M84Nh6cjyyS55/p+XE7227 intact-crc:C0FE43B3747FC8EB|rigid:IY/eIY0l+upAb7fqCoqMGKrc9KU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20153 uniprotkb:P49869 intact:EBI-149021|uniprotkb:Q9W535|ensemblmetazoa:FBpp0070332|ensemblmetazoa:FBpp0305937 intact:EBI-869754|uniprotkb:O18383|uniprotkb:Q9VIK4|intact:EBI-3415490|ensemblmetazoa:FBpp0080927 psi-mi:usp_drome(display_long)|uniprotkb:usp(gene name)|psi-mi:usp(display_short)|uniprotkb:Cf1(gene name synonym)|uniprotkb:NR2B4(gene name synonym)|uniprotkb:CG4380(orf name)|uniprotkb:XR2C(gene name synonym)|uniprotkb:Chorion factor 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 4(gene name synonym) psi-mi:hr38_drome(display_long)|uniprotkb:Nuclear receptor subfamily 4 group A member 4(gene name synonym)|uniprotkb:Hr38(gene name)|psi-mi:Hr38(display_short)|uniprotkb:NR4A4(gene name synonym)|uniprotkb:CG1864(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873242 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476781.1|flybase:FBgn0003964|refseq:NP_001259168.1|dip:DIP-645N|ensemblmetazoa:FBgn0003964(gene)|ensemblmetazoa:FBtr0070346(transcript)|ensemblmetazoa:FBtr0333803(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|reactome:R-DME-9707564|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006697"(ecdysone biosynthetic process)|go:"GO:0007281"(germ cell development)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007552"(metamorphosis)|go:"GO:0008230"(ecdysone receptor holocomplex)|reactome:R-DME-9623433|go:"GO:0008232"(activator ecdysone receptor complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016319"(mushroom body development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0035073"(pupariation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0042562"(hormone binding)|go:"GO:0042594"(response to starvation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071390"(cellular response to ecdysone)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1HG4|rcsb pdb:1R0O|rcsb pdb:2HAN|reactome:R-DME-159418|reactome:R-DME-200425|reactome:R-DME-204174|reactome:R-DME-381340|reactome:R-DME-383280|reactome:R-DME-400206|reactome:R-DME-5362517|reactome:R-DME-9029569|reactome:R-DME-9616222 refseq:NP_477119.1|flybase:FBgn0014859|dip:DIP-929N|ensemblmetazoa:FBgn0014859(gene)|ensemblmetazoa:FBtr0081397(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042335"(cuticle development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048082"(regulation of adult chitin-containing cuticle pigmentation)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1PDU|reactome:R-DME-198693|reactome:R-DME-383280 pubmed:12809604(see-also)|pubmed:7644522(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:amASW54ZH6dtdZULbgr9lt4GbBE7227 rogid:E3cL+MpOb5NWc0PjkVtp2kzo1oY7227 intact-crc:27880D659D17CECB|rigid:XtPJmTKEuzWYtgfCseklERw3a9E false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24142 uniprotkb:Q24142 intact:EBI-163133|uniprotkb:A4V288|uniprotkb:Q24108|uniprotkb:Q8IPT4|uniprotkb:Q9VP28|ensemblmetazoa:FBpp0078044|ensemblmetazoa:FBpp0078045|ensemblmetazoa:FBpp0089291|ensemblmetazoa:FBpp0292670|ensemblmetazoa:FBpp0292671 intact:EBI-163133|uniprotkb:A4V288|uniprotkb:Q24108|uniprotkb:Q8IPT4|uniprotkb:Q9VP28|ensemblmetazoa:FBpp0078044|ensemblmetazoa:FBpp0078045|ensemblmetazoa:FBpp0089291|ensemblmetazoa:FBpp0292670|ensemblmetazoa:FBpp0292671 psi-mi:hr78_drome(display_long)|uniprotkb:Hr78(gene name)|psi-mi:Hr78(display_short)|uniprotkb:Hr78D(gene name synonym)|uniprotkb:NR2D1(gene name synonym)|uniprotkb:CG7199(orf name)|uniprotkb:Nuclear receptor XR78E/F(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group D member 1(gene name synonym) psi-mi:hr78_drome(display_long)|uniprotkb:Hr78(gene name)|psi-mi:Hr78(display_short)|uniprotkb:Hr78D(gene name synonym)|uniprotkb:NR2D1(gene name synonym)|uniprotkb:CG7199(orf name)|uniprotkb:Nuclear receptor XR78E/F(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group D member 1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873246 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0015239(gene)|ensemblmetazoa:FBtr0078390(transcript)|ensemblmetazoa:FBtr0078392(transcript)|ensemblmetazoa:FBtr0303653(transcript)|ensemblmetazoa:FBtr0303654(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0035002"(liquid clearance, open tracheal system)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-DME-383280|ensemblmetazoa:FBtr0078389(transcript)|refseq:NP_001189151.1|refseq:NP_001189152.1|refseq:NP_524203.2|refseq:NP_730636.1|refseq:NP_730637.1|refseq:NP_996137.1|flybase:FBgn0015239 ensemblmetazoa:FBgn0015239(gene)|ensemblmetazoa:FBtr0078390(transcript)|ensemblmetazoa:FBtr0078392(transcript)|ensemblmetazoa:FBtr0303653(transcript)|ensemblmetazoa:FBtr0303654(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0035002"(liquid clearance, open tracheal system)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-DME-383280|ensemblmetazoa:FBtr0078389(transcript)|refseq:NP_001189151.1|refseq:NP_001189152.1|refseq:NP_524203.2|refseq:NP_730636.1|refseq:NP_730637.1|refseq:NP_996137.1|flybase:FBgn0015239 pubmed:7479823(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:/5+4LQ490LpPW0I+g8HfJJN6IyI7227 rogid:/5+4LQ490LpPW0I+g8HfJJN6IyI7227 intact-crc:5D0998D80C03A860|rigid:usr58L5aduA0YtvasrL6wWZKUdo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P19339 uniprotkb:P48810 intact:EBI-199576|uniprotkb:P19340|uniprotkb:Q0KHV2|uniprotkb:Q26466|uniprotkb:Q2MGN7|uniprotkb:Q2MGN8|uniprotkb:Q2MGN9|uniprotkb:Q2MGP1|uniprotkb:Q7KVU6|uniprotkb:Q7YZ92|uniprotkb:Q8IRQ1|uniprotkb:Q99141|uniprotkb:Q9TYF5|uniprotkb:Q9W3S6|uniprotkb:A4V435|uniprotkb:A4V437|uniprotkb:A4V434|uniprotkb:A4V436|uniprotkb:C9QP40|uniprotkb:D0IQK2|uniprotkb:D3PFI6|uniprotkb:E1JJI8|uniprotkb:E1JJI9|uniprotkb:E1JJJ0|uniprotkb:E1JJJ2|uniprotkb:E1JJJ3|ensemblmetazoa:FBpp0303697|ensemblmetazoa:FBpp0303704|ensemblmetazoa:FBpp0303710 intact:EBI-93570|uniprotkb:Q24486|uniprotkb:Q8INH0|uniprotkb:Q9VFT2|ensemblmetazoa:FBpp0082316|ensemblmetazoa:FBpp0289817|ensemblmetazoa:FBpp0302741|ensemblmetazoa:FBpp0306562 psi-mi:sxl_drome(display_long)|uniprotkb:Sxl(gene name)|psi-mi:Sxl(display_short)|uniprotkb:Sx1(gene name synonym)|uniprotkb:CG43770(orf name) psi-mi:rb87f_drome(display_long)|uniprotkb:Hrb87F(gene name)|psi-mi:Hrb87F(display_short)|uniprotkb:hrp36(gene name synonym)|uniprotkb:HRP36.1 protein(gene name synonym)|uniprotkb:Protein P11(gene name synonym)|uniprotkb:CG12749(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873250 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_727161.3|refseq:NP_001027062.1|refseq:NP_001027063.1|refseq:NP_001027064.1|refseq:NP_001027065.1|refseq:NP_001027066.1|refseq:NP_001162686.1|refseq:NP_001162687.1|refseq:NP_001162688.1|refseq:NP_001162689.1|refseq:NP_001162690.1|refseq:NP_524791.3|refseq:NP_727160.2|refseq:NP_727162.2|refseq:NP_727163.2|refseq:NP_727164.2|refseq:NP_727165.2|refseq:NP_727166.2|refseq:NP_727167.2|refseq:NP_727168.1|refseq:NP_001259305.1|refseq:NP_001259306.1|flybase:FBgn0264270|dip:DIP-44607N|ensemblmetazoa:FBgn0264270(gene)|ensemblmetazoa:FBtr0331255(transcript)|ensemblmetazoa:FBtr0331262(transcript)|ensemblmetazoa:FBtr0331268(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007530"(sex determination)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0007548"(sex differentiation)|go:"GO:0007549"(dosage compensation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0009994"(oocyte differentiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018993"(somatic sex determination)|go:"GO:0030237"(female sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990399"(epithelium regeneration)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006546(Sex-lethal splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P19339|rcsb pdb:1B7F|rcsb pdb:1SXL|rcsb pdb:2SXL|rcsb pdb:3SXL|rcsb pdb:4QQB refseq:NP_001163602.1|refseq:NP_476807.1|flybase:FBgn0004237|ensemblmetazoa:FBgn0004237(gene)|ensemblmetazoa:FBtr0082851(transcript)|ensemblmetazoa:FBtr0300590(transcript)|ensemblmetazoa:FBtr0310621(transcript)|ensemblmetazoa:FBtr0334495(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008585"(female gonad development)|go:"GO:0009408"(response to heat)|go:"GO:0034046"("poly(G) binding")|go:"GO:0035062"(omega speckle)|go:"GO:0042594"(response to starvation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0000785"(chromatin)|refseq:NP_001262538.1|refseq:NP_476806.2 pubmed:9268369(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:OOLyyjkFbL8POQarQfx8Yhy8SV47227 rogid:0/zJfq5ck29psI8dANCI0L9/Qbw7227 intact-crc:79ABA5267116CCEE|rigid:c6N6Qa1SRBPsawmJQUg/fGW7ezk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P41073 uniprotkb:P48810 intact:EBI-522331|uniprotkb:Q8IGB1|uniprotkb:Q8MSV5|uniprotkb:Q9VVJ2|uniprotkb:Q9VVJ3|uniprotkb:Q9VVJ4|ensemblmetazoa:FBpp0074963 intact:EBI-93570|uniprotkb:Q24486|uniprotkb:Q8INH0|uniprotkb:Q9VFT2|ensemblmetazoa:FBpp0082316|ensemblmetazoa:FBpp0289817|ensemblmetazoa:FBpp0302741|ensemblmetazoa:FBpp0306562 psi-mi:pep_drome(display_long)|uniprotkb:Pep(gene name)|psi-mi:Pep(display_short)|uniprotkb:CG6143(orf name) psi-mi:rb87f_drome(display_long)|uniprotkb:Hrb87F(gene name)|psi-mi:Hrb87F(display_short)|uniprotkb:hrp36(gene name synonym)|uniprotkb:HRP36.1 protein(gene name synonym)|uniprotkb:Protein P11(gene name synonym)|uniprotkb:CG12749(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873254 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524858.1|refseq:NP_730290.3|refseq:NP_996118.1|flybase:FBgn0004401|ensemblmetazoa:FBgn0004401(gene)|ensemblmetazoa:FBtr0075199(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR026811|interpro:IPR036236|mint:P41073|dip:DIP-20217N|refseq:NP_001246817.1 refseq:NP_001163602.1|refseq:NP_476807.1|flybase:FBgn0004237|ensemblmetazoa:FBgn0004237(gene)|ensemblmetazoa:FBtr0082851(transcript)|ensemblmetazoa:FBtr0300590(transcript)|ensemblmetazoa:FBtr0310621(transcript)|ensemblmetazoa:FBtr0334495(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008585"(female gonad development)|go:"GO:0009408"(response to heat)|go:"GO:0034046"("poly(G) binding")|go:"GO:0035062"(omega speckle)|go:"GO:0042594"(response to starvation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0000785"(chromatin)|refseq:NP_001262538.1|refseq:NP_476806.2 pubmed:10713453(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:29/JZMsZ78Uyh3MQGEfFkmct0S87227 rogid:0/zJfq5ck29psI8dANCI0L9/Qbw7227 intact-crc:F2F2C61A3B806111|rigid:jfx3DLO5wYb3hHGwR4yNIlQHEqE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q04047 uniprotkb:P48810 intact:EBI-134012|uniprotkb:Q24261|uniprotkb:Q59E42|uniprotkb:Q9VXH1|ensemblmetazoa:FBpp0074011|ensemblmetazoa:FBpp0309274 intact:EBI-93570|uniprotkb:Q24486|uniprotkb:Q8INH0|uniprotkb:Q9VFT2|ensemblmetazoa:FBpp0082316|ensemblmetazoa:FBpp0289817|ensemblmetazoa:FBpp0302741|ensemblmetazoa:FBpp0306562 psi-mi:nona_drome(display_long)|uniprotkb:nonA(gene name)|psi-mi:nonA(display_short)|uniprotkb:CG4211(orf name)|uniprotkb:Puff-specific protein Bj6(gene name synonym) psi-mi:rb87f_drome(display_long)|uniprotkb:Hrb87F(gene name)|psi-mi:Hrb87F(display_short)|uniprotkb:hrp36(gene name synonym)|uniprotkb:HRP36.1 protein(gene name synonym)|uniprotkb:Protein P11(gene name synonym)|uniprotkb:CG12749(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873258 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014747.1|refseq:NP_523367.2|flybase:FBgn0004227|refseq:NP_001285324.1|ensemblmetazoa:FBgn0004227(gene)|ensemblmetazoa:FBtr0074232(transcript)|ensemblmetazoa:FBtr0340313(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007601"(visual perception)|go:"GO:0007632"(visual behavior)|go:"GO:0042331"(phototaxis)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR035979|mint:Q04047 refseq:NP_001163602.1|refseq:NP_476807.1|flybase:FBgn0004237|ensemblmetazoa:FBgn0004237(gene)|ensemblmetazoa:FBtr0082851(transcript)|ensemblmetazoa:FBtr0300590(transcript)|ensemblmetazoa:FBtr0310621(transcript)|ensemblmetazoa:FBtr0334495(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005737"(cytoplasm)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008585"(female gonad development)|go:"GO:0009408"(response to heat)|go:"GO:0034046"("poly(G) binding")|go:"GO:0035062"(omega speckle)|go:"GO:0042594"(response to starvation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0000785"(chromatin)|refseq:NP_001262538.1|refseq:NP_476806.2 pubmed:10585281(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:4ART7xru9saoL461MJiyASUWfLo7227 rogid:0/zJfq5ck29psI8dANCI0L9/Qbw7227 intact-crc:40CB844E283BDC21|rigid:IzMq1hSg3K99R9rbSQxjVIKis8Q false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q08605 uniprotkb:P22813 intact:EBI-300317|uniprotkb:Q08083|uniprotkb:Q7JN57|uniprotkb:Q8MYL3|uniprotkb:Q8T387|uniprotkb:Q9V3X7|uniprotkb:Q9VUH2|uniprotkb:O18349|uniprotkb:O18350|uniprotkb:O18526 intact:EBI-130048|uniprotkb:Q9V8C1|ensemblmetazoa:FBpp0085961 psi-mi:gaga_drome(display_long)|uniprotkb:Trl(gene name)|psi-mi:Trl(display_short)|uniprotkb:GAGA(gene name synonym)|uniprotkb:TFGAGA(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:GAGA factor(gene name synonym)|uniprotkb:Adh transcription factor 2(gene name synonym)|uniprotkb:Neural conserved at 70F(gene name synonym)|uniprotkb:Adf-2(gene name synonym)|uniprotkb:Nc70F(gene name synonym)|uniprotkb:CG33261(orf name) psi-mi:hsf_drome(display_long)|uniprotkb:Hsf(gene name)|psi-mi:Hsf(display_short)|uniprotkb:CG5748(orf name)|uniprotkb:Heat shock transcription factor(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873262 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000280"(nuclear division)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007549"(dosage compensation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0034728"(nucleosome organization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051301"(cell division)|go:"GO:1901409"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:1990000"(amyloid fibril formation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR015318(Zinc finger, GAGAG binding factor)|rcsb pdb:1YUI|rcsb pdb:1YUJ|go:"GO:0035075"(response to ecdysone)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043044"|refseq:NP_001034014.1|refseq:NP_996077.1|refseq:NP_996078.1|refseq:NP_996079.1|refseq:NP_996080.1|refseq:NP_996081.1|refseq:NP_996082.1|flybase:FBgn0013263 refseq:NP_476575.1|flybase:FBgn0001222|ensemblmetazoa:FBgn0001222(gene)|ensemblmetazoa:FBtr0086782(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009408"(response to heat)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050832"(defense response to fungus)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1HKS|rcsb pdb:1HKT|reactome:R-DME-3371453|reactome:R-DME-3371511|reactome:R-DME-3371568|reactome:R-DME-3371571|dip:DIP-20041N pubmed:9407112(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:s2lpiYJCLr9x3aKiQRvlG3gE9nk7227 rogid:xliYPBKMVWUtd+/gAbMtbunTDrk7227 intact-crc:70D0F8CD059C4DE2|rigid:VYUgoBiOU181bUBnscMnUJe2FSo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20227 uniprotkb:P22813 intact:EBI-169179|uniprotkb:Q9W2D8|ensemblmetazoa:FBpp0071596 intact:EBI-130048|uniprotkb:Q9V8C1|ensemblmetazoa:FBpp0085961 psi-mi:tbp_drome(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:CG9874(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:hsf_drome(display_long)|uniprotkb:Hsf(gene name)|psi-mi:Hsf(display_short)|uniprotkb:CG5748(orf name)|uniprotkb:Heat shock transcription factor(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873266 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523805.1|flybase:FBgn0003687|ensemblmetazoa:FBgn0003687(gene)|ensemblmetazoa:FBtr0071679(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519|dip:DIP-80N refseq:NP_476575.1|flybase:FBgn0001222|ensemblmetazoa:FBgn0001222(gene)|ensemblmetazoa:FBtr0086782(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009408"(response to heat)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050832"(defense response to fungus)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1HKS|rcsb pdb:1HKT|reactome:R-DME-3371453|reactome:R-DME-3371511|reactome:R-DME-3371568|reactome:R-DME-3371571|dip:DIP-20041N pubmed:9407112(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:eRlX8luNoF4M7SFmEnxKSbI6FJo7227 rogid:xliYPBKMVWUtd+/gAbMtbunTDrk7227 intact-crc:76A8170406FFF955|rigid:n7ZmVxoq2+mmdI55nAYwpNp9WSQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O76522 uniprotkb:P22813 intact:EBI-499003 intact:EBI-130048|uniprotkb:Q9V8C1|ensemblmetazoa:FBpp0085961 psi-mi:o76522_drome(display_long)|uniprotkb:CG9423(orf name)|uniprotkb:Kap-alpha3(gene name)|psi-mi:Kap-alpha3(display_short)|uniprotkb:Kap-alpha-3(gene name synonym) psi-mi:hsf_drome(display_long)|uniprotkb:Hsf(gene name)|psi-mi:Hsf(display_short)|uniprotkb:CG5748(orf name)|uniprotkb:Heat shock transcription factor(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873270 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0027338|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0009411"(response to UV)|go:"GO:0017022"(myosin binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975 refseq:NP_476575.1|flybase:FBgn0001222|ensemblmetazoa:FBgn0001222(gene)|ensemblmetazoa:FBtr0086782(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009408"(response to heat)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050832"(defense response to fungus)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1HKS|rcsb pdb:1HKT|reactome:R-DME-3371453|reactome:R-DME-3371511|reactome:R-DME-3371568|reactome:R-DME-3371571|dip:DIP-20041N pubmed:11546751(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Ry3o76SK18N9E4hRVDYUCOJl6U07227 rogid:xliYPBKMVWUtd+/gAbMtbunTDrk7227 intact-crc:4B3567AAB6A67D33|rigid:EkYXPsdsxmO2yG69yPD25GIHDnA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9BIS2 uniprotkb:P22813 intact:EBI-422052|uniprotkb:B0BNN7|uniprotkb:Q5I7H2|uniprotkb:Q5I7H4|uniprotkb:Q5I7H6|uniprotkb:Q5I7H8|uniprotkb:Q5I7I3|uniprotkb:Q5I7I6|uniprotkb:Q5I7I8|uniprotkb:P02824|uniprotkb:Q53XF0|uniprotkb:Q9BIS1|uniprotkb:Q9I7J6|ensemblmetazoa:FBpp0082106|ensemblmetazoa:FBpp0082107 intact:EBI-130048|uniprotkb:Q9V8C1|ensemblmetazoa:FBpp0085961 psi-mi:hsp73_drome(display_long)|uniprotkb:HSP70-87C1(gene name synonym)|uniprotkb:Hsp70Bb(gene name)|psi-mi:Hsp70Bb(display_short)|uniprotkb:CG31359(orf name) psi-mi:hsf_drome(display_long)|uniprotkb:Hsf(gene name)|psi-mi:Hsf(display_short)|uniprotkb:CG5748(orf name)|uniprotkb:Heat shock transcription factor(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873274 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524927.2|refseq:NP_650209.1|flybase:FBgn0013278|ensemblmetazoa:FBgn0013278(gene)|ensemblmetazoa:FBgn0013279(gene)|ensemblmetazoa:FBtr0082637(transcript)|ensemblmetazoa:FBtr0082638(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009408"(response to heat)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0035080"(heat shock-mediated polytene chromosome puffing)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|reactome:R-DME-3371453|reactome:R-DME-3371497|reactome:R-DME-3371571|reactome:R-DME-450408|reactome:R-DME-6798695 refseq:NP_476575.1|flybase:FBgn0001222|ensemblmetazoa:FBgn0001222(gene)|ensemblmetazoa:FBtr0086782(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009408"(response to heat)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050832"(defense response to fungus)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1HKS|rcsb pdb:1HKT|reactome:R-DME-3371453|reactome:R-DME-3371511|reactome:R-DME-3371568|reactome:R-DME-3371571|dip:DIP-20041N pubmed:7935376(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:LG3jrV5/vMwOhQ9E+fq+HzW0bkk7227 rogid:xliYPBKMVWUtd+/gAbMtbunTDrk7227 intact-crc:98801170DDA61998|rigid:cnwh1C+QCmEwbSZJBIF09WYdEmc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P52304 uniprotkb:P02828 intact:EBI-163922|uniprotkb:A4V258|uniprotkb:Q9VWB2|ensemblmetazoa:FBpp0074608|ensemblmetazoa:FBpp0099722 intact:EBI-136814|ensemblmetazoa:FBpp0072904|ensemblmetazoa:FBpp0305095|uniprotkb:P92174|uniprotkb:P92202|uniprotkb:Q9VZT3 psi-mi:polo_drome(display_long)|uniprotkb:polo(gene name)|psi-mi:polo(display_short)|uniprotkb:CG12306(orf name) psi-mi:hsp83_drome(display_long)|uniprotkb:Hsp83(gene name)|psi-mi:Hsp83(display_short)|uniprotkb:Hsp82(gene name synonym)|uniprotkb:HSP 82(gene name synonym)|uniprotkb:Hsp90(gene name synonym)|uniprotkb:CG1242(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873290 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014592.1|refseq:NP_524179.2|flybase:FBgn0003124|ensemblmetazoa:FBgn0003124(gene)|ensemblmetazoa:FBtr0074839(transcript)|ensemblmetazoa:FBtr0100318(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007058"(spindle assembly involved in female meiosis II)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007147"(female meiosis II)|go:"GO:0007344"(pronuclear fusion)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0030496"(midbody)|go:"GO:0030726"(male germline ring canal formation)|go:"GO:0030954"(astral microtubule nucleation)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035044"(sperm aster formation)|go:"GO:0035046"(pronuclear migration)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0048600"(oocyte fate commitment)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|reactome:R-DME-156711|reactome:R-DME-162658|reactome:R-DME-174178|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-68881|reactome:R-DME-68884|reactome:R-DME-69273|reactome:R-DME-9648025|dip:DIP-18462N go:"GO:0005158"(insulin receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|ensemblmetazoa:FBgn0001233(gene)|ensemblmetazoa:FBtr0073040(transcript)|ensemblmetazoa:FBtr0332873(transcript)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0009631"(cold acclimation)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0030911"(TPR domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0101031"(chaperone complex)|go:"GO:0106161"(obsolete positive regulation of small RNA loading onto RISC)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|reactome:R-DME-1227986|reactome:R-DME-1474151|reactome:R-DME-2029482|reactome:R-DME-203615|reactome:R-DME-3371497|reactome:R-DME-3371511|refseq:NP_523899.1|flybase:FBgn0001233|refseq:NP_001261362.1|go:"GO:0043248"(proteasome assembly)|dip:DIP-17366N|reactome:R-DME-399954|reactome:R-DME-5218920|reactome:R-DME-5675482|reactome:R-DME-6798695|reactome:R-DME-3371571|reactome:R-DME-8863795|reactome:R-DME-8937144|reactome:R-DME-8939211|reactome:R-DME-9009391|reactome:R-DME-9013418|reactome:R-DME-9652282 pubmed:11387220(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6tWOAy0eGhYWKuTzd50pYRSv62A7227 rogid:PS2fd2RD7YWygzaMqF40SNCb2xQ7227 intact-crc:563E48C5E4181BA8|rigid:rMZHEJ1pQhuSlK8weBDIrzYlXjY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P11346 uniprotkb:P02828 intact:EBI-664624|uniprotkb:Q9W4Z3|uniprotkb:Q8I086|uniprotkb:Q8I0D9|uniprotkb:Q8ISE1|uniprotkb:Q8ISE2|uniprotkb:Q8ISE3|uniprotkb:Q9NEH9|uniprotkb:A8JUV5|uniprotkb:Q0KHW7|ensemblmetazoa:FBpp0070385|ensemblmetazoa:FBpp0310458 intact:EBI-136814|ensemblmetazoa:FBpp0072904|ensemblmetazoa:FBpp0305095|uniprotkb:P92174|uniprotkb:P92202|uniprotkb:Q9VZT3 psi-mi:kraf1_drome(display_long)|uniprotkb:Raf(gene name)|psi-mi:Raf(display_short)|uniprotkb:Protein pole-hole(gene name synonym)|uniprotkb:ph(gene name synonym)|uniprotkb:phl(gene name synonym)|uniprotkb:CG2845(orf name) psi-mi:hsp83_drome(display_long)|uniprotkb:Hsp83(gene name)|psi-mi:Hsp83(display_short)|uniprotkb:Hsp82(gene name synonym)|uniprotkb:HSP 82(gene name synonym)|uniprotkb:Hsp90(gene name synonym)|uniprotkb:CG1242(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873294 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525047.1|flybase:FBgn0003079|refseq:NP_001096867.3|dip:DIP-29769N|ensemblmetazoa:FBgn0003079(gene)|ensemblmetazoa:FBtr0070401(transcript)|ensemblmetazoa:FBtr0344007(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0002168"(instar larval development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007552"(metamorphosis)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042386"(hemocyte differentiation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029071|reactome:R-DME-1295596|reactome:R-DME-170968|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-432553|reactome:R-DME-5621575|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5675482 go:"GO:0005158"(insulin receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|ensemblmetazoa:FBgn0001233(gene)|ensemblmetazoa:FBtr0073040(transcript)|ensemblmetazoa:FBtr0332873(transcript)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0009631"(cold acclimation)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0030911"(TPR domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0101031"(chaperone complex)|go:"GO:0106161"(obsolete positive regulation of small RNA loading onto RISC)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|reactome:R-DME-1227986|reactome:R-DME-1474151|reactome:R-DME-2029482|reactome:R-DME-203615|reactome:R-DME-3371497|reactome:R-DME-3371511|refseq:NP_523899.1|flybase:FBgn0001233|refseq:NP_001261362.1|go:"GO:0043248"(proteasome assembly)|dip:DIP-17366N|reactome:R-DME-399954|reactome:R-DME-5218920|reactome:R-DME-5675482|reactome:R-DME-6798695|reactome:R-DME-3371571|reactome:R-DME-8863795|reactome:R-DME-8937144|reactome:R-DME-8939211|reactome:R-DME-9009391|reactome:R-DME-9013418|reactome:R-DME-9652282 pubmed:9155022(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:rbvsd7+5RvYrFoXyonEM6Li84hM7227 rogid:PS2fd2RD7YWygzaMqF40SNCb2xQ7227 intact-crc:0B40E25CF1D25C52|rigid:qg6c9hZhueyzFe8Wzan2mOZsdn8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O96757 uniprotkb:Q07407 intact:EBI-74922 intact:EBI-74984|uniprotkb:O18371|uniprotkb:Q26294|uniprotkb:Q9VED5|uniprotkb:A4V320|ensemblmetazoa:FBpp0082970|ensemblmetazoa:FBpp0082971|ensemblmetazoa:FBpp0082972 psi-mi:o96757_drome(display_long)|uniprotkb:stumps(gene name)|psi-mi:stumps(display_short)|uniprotkb:dof(gene name synonym)|uniprotkb:CG31317(orf name) psi-mi:fgfr1_drome(display_long)|uniprotkb:htl(gene name)|psi-mi:htl(display_short)|uniprotkb:FR1(gene name synonym)|uniprotkb:Tk1(gene name synonym)|uniprotkb:CG7223(orf name)|uniprotkb:Protein heartless(gene name synonym)|uniprotkb:Tyrosine kinase 1(gene name synonym)|uniprotkb:DmHD-38(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873298 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0020299|go:"GO:0007498"(mesoderm development)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0021782"(glial cell development)|go:"GO:0042802"(identical protein binding)|interpro:IPR017893|interpro:IPR035897|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0007424"(open tracheal system development) refseq:NP_524394.2|refseq:NP_732286.1|refseq:NP_732287.1|flybase:FBgn0010389|ensemblmetazoa:FBgn0010389(gene)|ensemblmetazoa:FBtr0083548(transcript)|ensemblmetazoa:FBtr0083549(transcript)|ensemblmetazoa:FBtr0083550(transcript)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005007"(fibroblast growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007280"(pole cell migration)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007431"(salivary gland development)|go:"GO:0007493"(endodermal cell fate determination)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007523"(larval visceral muscle development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008354"(germ cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0021782"(glial cell development)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0042065"(glial cell growth)|go:"GO:0043235"(receptor complex)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0048542"(lymph gland development)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055001"(muscle cell development)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0098975"(postsynapse of neuromuscular junction)|go:"GO:0110122"(myotube cell migration)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:2001107"(negative regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016248(Fibroblast growth factor receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036179|reactome:R-DME-109704|reactome:R-DME-1257604|reactome:R-DME-1307965|reactome:R-DME-190322|reactome:R-DME-190370|reactome:R-DME-190371|reactome:R-DME-190372|reactome:R-DME-190373|reactome:R-DME-190374|reactome:R-DME-5654219|reactome:R-DME-5654227|reactome:R-DME-5654228|reactome:R-DME-5654687|reactome:R-DME-5654688|reactome:R-DME-5654689|reactome:R-DME-5654693|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654710|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5654720|reactome:R-DME-5654726|reactome:R-DME-5654732|reactome:R-DME-5654733|reactome:R-DME-5673001|reactome:R-DME-6811558 pubmed:14993266(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:m4z7q+AYHJsoJ3FMJ5FxnC/olaw7227 rogid:TbGJaZTKQbblXdwRafekth09o4A7227 intact-crc:823AEB5B66D0FE47|rigid:5a3TWnJKKo9dBpy3s5Sv44WHVos false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P12982 uniprotkb:Q9V3C7 intact:EBI-152633|uniprotkb:Q4PIY5|uniprotkb:Q9VG75|ensemblmetazoa:FBpp0082067 intact:EBI-95729|ensemblmetazoa:FBpp0076099 psi-mi:pp12_drome(display_long)|uniprotkb:Pp1-87B(gene name)|psi-mi:Pp1-87B(display_short)|uniprotkb:CG5650(orf name) psi-mi:q9v3c7_drome(display_long)|uniprotkb:I-2(gene name)|psi-mi:I-2(display_short)|uniprotkb:inhibitor-2(gene name synonym)|uniprotkb:I-2Dm(gene name synonym)|uniprotkb:Dmel_CG10574(orf name)|uniprotkb:DI-2(gene name synonym)|uniprotkb:Dm I-2(gene name synonym)|uniprotkb:Dmel\CG10574(gene name synonym)|uniprotkb:I-2PP1(gene name synonym)|uniprotkb:SET(gene name synonym)|uniprotkb:CG10574(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873302 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524937.1|flybase:FBgn0004103|ensemblmetazoa:FBgn0004103(gene)|ensemblmetazoa:FBtr0082595(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007611"(learning or memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008355"(olfactory learning)|go:"GO:0008542"(visual learning)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030261"(chromosome condensation)|go:"GO:0040011"(locomotion)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|go:"GO:0005737"(cytoplasm)|reactome:R-DME-350416|reactome:R-DME-350480|reactome:R-DME-538898|go:"GO:0005700"(polytene chromosome)|dip:DIP-18465N refseq:NP_524013.1|flybase:FBgn0028429|ensemblmetazoa:FBgn0028429(gene)|ensemblmetazoa:FBtr0076370(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007062("Protein phosphatase inhibitor 2 (IPP-2)") pubmed:10587451(see-also)|pubmed:12750335(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:wYZDYWZEbdafO7gAM+avnFnIF9Q7227 rogid:Ags55wNBOzMzDZSeYLLaXPA8Ovw7227 intact-crc:1BF1DD835E02BA1F|rigid:JMby25AfoAbos1P5iSwAxSEQqwU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VKN7 uniprotkb:Q8IGP7 intact:EBI-118412|uniprotkb:Q9XTQ0|ensemblmetazoa:FBpp0079769 intact:EBI-869808|ensemblmetazoa:FBpp0088035 psi-mi:aurkb_drome(display_long)|uniprotkb:aurB(gene name)|psi-mi:aurB(display_short)|uniprotkb:IPL1/Aurora-like protein kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Ial(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-B(gene name synonym)|uniprotkb:ial(gene name synonym)|uniprotkb:CG6620(orf name) psi-mi:q8igp7_drome(display_long)|uniprotkb:Incenp(gene name)|psi-mi:Incenp(display_short)|uniprotkb:CG12165(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873306 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477336.1|flybase:FBgn0024227|ensemblmetazoa:FBgn0024227(gene)|ensemblmetazoa:FBtr0080180(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006325"(chromatin organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030496"(midbody)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0051233"(spindle midzone)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061952"(midbody abscission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990385"(meiotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028772|interpro:IPR030616|reactome:R-DME-174178|reactome:R-DME-4615885|reactome:R-DME-6804756 flybase:FBgn0260991|ensemblmetazoa:FBgn0260991(gene)|ensemblmetazoa:FBtr0088961(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0007065"(male meiosis sister chromatid cohesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1902412"(regulation of mitotic cytokinesis)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990385"(meiotic spindle midzone)|interpro:IPR005635(Inner centromere protein, ARK binding region)|interpro:IPR039130 pubmed:11352945(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:RuIbYEJ93iyYiQpITOftFN7pMJI7227 rogid:BdD5jx/hv477hjaScA94luGdl/s7227 intact-crc:515015BE2217C585|rigid:tiJmhBni0RmrFkM6CcjE3j3KRXA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P02299 uniprotkb:Q9VKN7 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 intact:EBI-118412|uniprotkb:Q9XTQ0|ensemblmetazoa:FBpp0079769 psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:aurkb_drome(display_long)|uniprotkb:aurB(gene name)|psi-mi:aurB(display_short)|uniprotkb:IPL1/Aurora-like protein kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Ial(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-B(gene name synonym)|uniprotkb:ial(gene name synonym)|uniprotkb:CG6620(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873310 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231 refseq:NP_477336.1|flybase:FBgn0024227|ensemblmetazoa:FBgn0024227(gene)|ensemblmetazoa:FBtr0080180(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006325"(chromatin organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030496"(midbody)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0051233"(spindle midzone)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061952"(midbody abscission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990385"(meiotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028772|interpro:IPR030616|reactome:R-DME-174178|reactome:R-DME-4615885|reactome:R-DME-6804756 pubmed:11266459(see-also)|pubmed:11352945(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 rogid:RuIbYEJ93iyYiQpITOftFN7pMJI7227 intact-crc:D82ABB3870DF0051|rigid:j4Sj/opkwc7QM7jZyw8pfx6epvg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24106 uniprotkb:Q24307 intact:EBI-135509|uniprotkb:Q9VVP1|ensemblmetazoa:FBpp0074899|ensemblmetazoa:FBpp0305084 intact:EBI-112046|uniprotkb:A4UZI4|uniprotkb:Q24115|uniprotkb:Q24149|uniprotkb:Q24177|uniprotkb:Q960U3|uniprotkb:Q9V7G1|ensemblmetazoa:FBpp0086431|ensemblmetazoa:FBpp0086432 psi-mi:hid_drome(display_long)|uniprotkb:hid(gene name)|psi-mi:hid(display_short)|uniprotkb:Protein head involution defective(gene name synonym)|uniprotkb:Protein wrinkled(gene name synonym)|uniprotkb:W(gene name synonym)|uniprotkb:CG5123(orf name) psi-mi:diap2_drome(display_long)|uniprotkb:Diap2(gene name)|psi-mi:Diap2(display_short)|uniprotkb:Apoptosis 2 inhibitor(gene name synonym)|uniprotkb:DIHA(gene name synonym)|uniprotkb:IAP homolog A(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:Iap2(gene name synonym)|uniprotkb:Ilp(gene name synonym)|uniprotkb:Inhibitor of apoptosis 2(gene name synonym)|uniprotkb:CG8293(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873314 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524136.2|flybase:FBgn0003997|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008219"(cell death)|go:"GO:0008258"(head involution)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010114"(response to red light)|go:"GO:0012501"(programmed cell death)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005739"(mitochondrion)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1904747"(positive regulation of apoptotic process involved in development)|go:"GO:1990525"(BIR domain binding)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|rcsb pdb:1JD6|ensemblmetazoa:FBgn0003997(gene)|ensemblmetazoa:FBtr0075133(transcript)|ensemblmetazoa:FBtr0332862(transcript)|go:"GO:0002165"(instar larval or pupal development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001262010.1|dip:DIP-20052N refseq:NP_477127.1|refseq:NP_788362.1|flybase:FBgn0015247|ensemblmetazoa:FBgn0015247(gene)|ensemblmetazoa:FBtr0087296(transcript)|ensemblmetazoa:FBtr0087297(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006964"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0022416"(chaeta development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-209447|reactome:R-DME-3769402|reactome:R-DME-5675482|reactome:R-DME-8948747|reactome:R-DME-8948751 pubmed:9584170(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:x/Jsu6gdz5rnLlOny3LOrreZP2c7227 rogid:DV11DOWYIDsW1ADpZuGD9UtXpYM7227 intact-crc:3927E53CBDA91D41|rigid:qOYCI+lrGuxmsLNN5ESHEOt+emk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24326 uniprotkb:Q24307 intact:EBI-869183 intact:EBI-112046|uniprotkb:A4UZI4|uniprotkb:Q24115|uniprotkb:Q24149|uniprotkb:Q24177|uniprotkb:Q960U3|uniprotkb:Q9V7G1|ensemblmetazoa:FBpp0086431|ensemblmetazoa:FBpp0086432 psi-mi:q24326_drome(display_long)|uniprotkb:tkv(gene name)|psi-mi:tkv(display_short)|uniprotkb:dtfr(gene name synonym)|uniprotkb:CG14026(orf name) psi-mi:diap2_drome(display_long)|uniprotkb:Diap2(gene name)|psi-mi:Diap2(display_short)|uniprotkb:Apoptosis 2 inhibitor(gene name synonym)|uniprotkb:DIHA(gene name synonym)|uniprotkb:IAP homolog A(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:Iap2(gene name synonym)|uniprotkb:Ilp(gene name synonym)|uniprotkb:Inhibitor of apoptosis 2(gene name synonym)|uniprotkb:CG8293(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873318 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0003716|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005025"(transforming growth factor beta receptor activity, type I)|go:"GO:0005524"(ATP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007391"(dorsal closure)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008354"(germ cell migration)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030721"(spectrosome organization)|go:"GO:0035215"(genital disc development)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0043235"(receptor complex)|go:"GO:0045202"(synapse)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0046332"(SMAD binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0060799"(transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification)|go:"GO:0061327"(anterior Malpighian tubule development)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|interpro:IPR000333(Activin type II receptor)|interpro:IPR000472(TGF-beta receptor/activin receptor, type I/II)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003605(TGF beta receptor, GS motif)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) refseq:NP_477127.1|refseq:NP_788362.1|flybase:FBgn0015247|ensemblmetazoa:FBgn0015247(gene)|ensemblmetazoa:FBtr0087296(transcript)|ensemblmetazoa:FBtr0087297(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006964"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0022416"(chaeta development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-209447|reactome:R-DME-3769402|reactome:R-DME-5675482|reactome:R-DME-8948747|reactome:R-DME-8948751 pubmed:9545255(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:FB2IWkOHoz7sCHdulTN4juLDwhk7227 rogid:DV11DOWYIDsW1ADpZuGD9UtXpYM7227 intact-crc:C2304B21D2A5771A|rigid:xLLS4oN45MBwYnO+SfjTKaMsX+s false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24475 uniprotkb:Q24307 intact:EBI-106786|uniprotkb:A0JQ43|uniprotkb:Q4V3S2|uniprotkb:Q9VVP7|ensemblmetazoa:FBpp0074886 intact:EBI-112046|uniprotkb:A4UZI4|uniprotkb:Q24115|uniprotkb:Q24149|uniprotkb:Q24177|uniprotkb:Q960U3|uniprotkb:Q9V7G1|ensemblmetazoa:FBpp0086431|ensemblmetazoa:FBpp0086432 psi-mi:rpr_drome(display_long)|uniprotkb:Protein reaper(gene name synonym)|uniprotkb:rpr(gene name)|psi-mi:rpr(display_short)|uniprotkb:CG4319(orf name) psi-mi:diap2_drome(display_long)|uniprotkb:Diap2(gene name)|psi-mi:Diap2(display_short)|uniprotkb:Apoptosis 2 inhibitor(gene name synonym)|uniprotkb:DIHA(gene name synonym)|uniprotkb:IAP homolog A(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:Iap2(gene name synonym)|uniprotkb:Ilp(gene name synonym)|uniprotkb:Inhibitor of apoptosis 2(gene name synonym)|uniprotkb:CG8293(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873322 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524138.1|flybase:FBgn0011706|dip:DIP-21897N|ensemblmetazoa:FBgn0011706(gene)|ensemblmetazoa:FBtr0075120(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008219"(cell death)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0012501"(programmed cell death)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0035193"(larval central nervous system remodeling)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis) refseq:NP_477127.1|refseq:NP_788362.1|flybase:FBgn0015247|ensemblmetazoa:FBgn0015247(gene)|ensemblmetazoa:FBtr0087296(transcript)|ensemblmetazoa:FBtr0087297(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006964"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0022416"(chaeta development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-209447|reactome:R-DME-3769402|reactome:R-DME-5675482|reactome:R-DME-8948747|reactome:R-DME-8948751 pubmed:9294184(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:dfUqX1oqC/PI0TTvY+EBfGyh5k47227 rogid:DV11DOWYIDsW1ADpZuGD9UtXpYM7227 intact-crc:23FDC256FF41C133|rigid:TIkFPfFarumYt7pMFj7F0kC9VlQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9XYF4 uniprotkb:O01382 intact:EBI-108311|ensemblmetazoa:FBpp0076076 intact:EBI-91422|uniprotkb:Q9VAH1|ensemblmetazoa:FBpp0084848 psi-mi:dronc_drome(display_long)|uniprotkb:Dronc(gene name)|psi-mi:Dronc(display_short)|uniprotkb:NEDD2-like caspase(gene name synonym)|uniprotkb:Nc(gene name synonym)|uniprotkb:CG8091(orf name) psi-mi:drice_drome(display_long)|uniprotkb:drICE(gene name synonym)|uniprotkb:CG7788(orf name)|uniprotkb:Drice(gene name)|psi-mi:Drice(display_short)|uniprotkb:ICE(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873326 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524017.1|flybase:FBgn0026404|dip:DIP-31484N|ensemblmetazoa:FBgn0026404(gene)|ensemblmetazoa:FBtr0076347(transcript)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007516"(hemocyte development)|go:"GO:0007552"(metamorphosis)|go:"GO:0008258"(head involution)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010623"(programmed cell death involved in cell development)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0010941"(regulation of cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0022416"(chaeta development)|go:"GO:0031638"(zymogen activation)|go:"GO:0035006"(melanization defense response)|go:"GO:0035070"(salivary gland histolysis)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043293"(apoptosome)|go:"GO:0045476"(nurse cell apoptotic process)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050700"(CARD domain binding)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|interpro:IPR033139|rcsb pdb:1Q4Q|rcsb pdb:2FP3|rcsb pdb:3J9K|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-140342|reactome:R-DME-198323|reactome:R-DME-264870|reactome:R-DME-351906|reactome:R-DME-418889|reactome:R-DME-448706|reactome:R-DME-449836 refseq:NP_524551.2|flybase:FBgn0019972|ensemblmetazoa:FBgn0019972(gene)|ensemblmetazoa:FBtr0085482(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0010165"(response to X-ray)|go:"GO:0010623"(programmed cell death involved in cell development)|go:"GO:0012501"(programmed cell death)|go:"GO:0016322"(neuron remodeling)|go:"GO:0035070"(salivary gland histolysis)|go:"GO:0035103"(sterol regulatory element binding protein cleavage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045476"(nurse cell apoptotic process)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:1990525"(BIR domain binding)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|rcsb pdb:3SIP|rcsb pdb:3SIR|reactome:R-DME-111465|reactome:R-DME-264870|reactome:R-DME-75153|dip:DIP-21838N pubmed:9774110(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:5OjYCr0Yvr0eiWhfG14i20fZwNA7227 rogid:aJREbCpkH2DICPbhBY7VVZe4qx07227 intact-crc:23F45CBB4D5208D2|rigid:TzFN2iNNNY5xCDD1OzZuseh12Hk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08928 uniprotkb:O01382 intact:EBI-188444|uniprotkb:Q9VMQ0|ensemblmetazoa:FBpp0078733|ensemblmetazoa:FBpp0297901|ensemblmetazoa:FBpp0297902|ensemblmetazoa:FBpp0312110 intact:EBI-91422|uniprotkb:Q9VAH1|ensemblmetazoa:FBpp0084848 psi-mi:lam0_drome(display_long)|uniprotkb:Lam(gene name)|psi-mi:Lam(display_short)|uniprotkb:CG6944(orf name) psi-mi:drice_drome(display_long)|uniprotkb:drICE(gene name synonym)|uniprotkb:CG7788(orf name)|uniprotkb:Drice(gene name)|psi-mi:Drice(display_short)|uniprotkb:ICE(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873330 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476616.1|flybase:FBgn0002525|refseq:NP_001245892.1|refseq:NP_001245893.1|refseq:NP_001285629.1|dip:DIP-2663N|ensemblmetazoa:FBgn0002525(gene)|ensemblmetazoa:FBtr0079100(transcript)|ensemblmetazoa:FBtr0307058(transcript)|ensemblmetazoa:FBtr0307059(transcript)|ensemblmetazoa:FBtr0346460(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007097"(nuclear migration)|go:"GO:0007110"(meiosis I cytokinesis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007569"(cell aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0048137"(spermatocyte division)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:2000433"(positive regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-DME-352238|reactome:R-DME-4419969|reactome:R-DME-9013405|reactome:R-DME-9035034 refseq:NP_524551.2|flybase:FBgn0019972|ensemblmetazoa:FBgn0019972(gene)|ensemblmetazoa:FBtr0085482(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0010165"(response to X-ray)|go:"GO:0010623"(programmed cell death involved in cell development)|go:"GO:0012501"(programmed cell death)|go:"GO:0016322"(neuron remodeling)|go:"GO:0035070"(salivary gland histolysis)|go:"GO:0035103"(sterol regulatory element binding protein cleavage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045476"(nurse cell apoptotic process)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:1990525"(BIR domain binding)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|rcsb pdb:3SIP|rcsb pdb:3SIR|reactome:R-DME-111465|reactome:R-DME-264870|reactome:R-DME-75153|dip:DIP-21838N pubmed:9321398(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Kuv16J8T6uZ7lIJaqjVrdn9x5WU7227 rogid:aJREbCpkH2DICPbhBY7VVZe4qx07227 intact-crc:93AD2B048DC66A97|rigid:d+HZ6nMqDdOzaljq5ajSNMOeTf0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8IP51 uniprotkb:P12080 intact:EBI-498443|ensemblmetazoa:FBpp0291871 intact:EBI-259113|uniprotkb:Q9VXB6|intact:EBI-9925499|intact:EBI-3415358|uniprotkb:E1JJN2|uniprotkb:Q8IR07|uniprotkb:Q8MSG3|ensemblmetazoa:FBpp0074131|ensemblmetazoa:FBpp0290567|ensemblmetazoa:FBpp0290568 psi-mi:q8ip51_drome(display_long)|uniprotkb:CG15288(gene name synonym)|uniprotkb:CG32970(gene name synonym)|uniprotkb:Wb(gene name synonym)|uniprotkb:wb(gene name)|psi-mi:wb(display_short)|uniprotkb:&agr1(gene name synonym)|uniprotkb:2(gene name synonym)|uniprotkb:2Lan(gene name synonym)|uniprotkb:2]](gene name synonym)|uniprotkb:A1(gene name synonym)|uniprotkb:"BEST:CK02229"(gene name synonym)|uniprotkb:"BG:DS03792.1"(gene name synonym)|uniprotkb:"BG:DS03792.2"(gene name synonym)|uniprotkb:CK02229(gene name synonym)|uniprotkb:CT35236(gene name synonym)|uniprotkb:DLAM(gene name synonym)|uniprotkb:Dmel\CG42677(gene name synonym)|uniprotkb:LM-A(gene name synonym)|uniprotkb:LanA1(gene name synonym)|uniprotkb:alpha2(gene name synonym)|uniprotkb:alpha[[1(gene name synonym)|uniprotkb:fus5(gene name synonym)|uniprotkb:"l(2)09437"(gene name synonym)|uniprotkb:"l(2)34Fb"(gene name synonym)|uniprotkb:"l(2)br1"(gene name synonym)|uniprotkb:l34Fb(gene name synonym)|uniprotkb:Dmel_CG42677(orf name)|uniprotkb:CG42677(orf name) psi-mi:ita2_drome(display_long)|uniprotkb:if(gene name)|psi-mi:if(display_short)|uniprotkb:CG9623(orf name)|uniprotkb:Position-specific antigen subunit alpha-2(gene name synonym)|uniprotkb:Protein inflated(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873334 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_723870.1|flybase:FBgn0261563|ensemblmetazoa:FBgn0261563(gene)|ensemblmetazoa:FBtr0302731(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0007502"(digestive tract mesoderm development)|go:"GO:0008406"(gonad development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0010669"(epithelial structure maintenance)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|reactome:R-DME-1474228|reactome:R-DME-3000157|reactome:R-DME-446107|interpro:IPR000034(Laminin B) refseq:NP_728021.2|refseq:NP_001162777.1|refseq:NP_001162778.1|refseq:NP_523378.2|flybase:FBgn0001250|dip:DIP-23111N|ensemblmetazoa:FBgn0001250(gene)|ensemblmetazoa:FBtr0074357(transcript)|ensemblmetazoa:FBtr0301353(transcript)|ensemblmetazoa:FBtr0301354(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007411"(axon guidance)|go:"GO:0007414"(axonal defasciculation)|go:"GO:0007419"(ventral cord development)|go:"GO:0007431"(salivary gland development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007475"(apposition of dorsal and ventral imaginal disc-derived wing surfaces)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008305"(integrin complex)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021551"(central nervous system morphogenesis)|go:"GO:0030239"(myofibril assembly)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0042383"(sarcolemma)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|reactome:R-DME-1566977|reactome:R-DME-198933|reactome:R-DME-202733|reactome:R-DME-2129379|reactome:R-DME-216083|reactome:R-DME-3000157|reactome:R-DME-3000170|reactome:R-DME-3000178|reactome:R-DME-354192|reactome:R-DME-5674135|reactome:R-DME-6798695 pubmed:9660786(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xiGrMY99fRqN9JQt5tH/nz7MblQ7227 rogid:srwsUuxnXhFxPinl41xbr5x8g207227 intact-crc:98725B20FD116E66|rigid:2h0GN3gzWbTZuCtbbBHUG35fSls false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VMD9 uniprotkb:P12080 intact:EBI-151709|intact:EBI-869822|uniprotkb:Q23984|uniprotkb:Q6NR23|ensemblmetazoa:FBpp0078905|ensemblmetazoa:FBpp0309850 intact:EBI-259113|uniprotkb:Q9VXB6|intact:EBI-9925499|intact:EBI-3415358|uniprotkb:E1JJN2|uniprotkb:Q8IR07|uniprotkb:Q8MSG3|ensemblmetazoa:FBpp0074131|ensemblmetazoa:FBpp0290567|ensemblmetazoa:FBpp0290568 psi-mi:tig_drome(display_long)|uniprotkb:Tig(gene name)|psi-mi:Tig(display_short)|uniprotkb:CG11527(orf name) psi-mi:ita2_drome(display_long)|uniprotkb:if(gene name)|psi-mi:if(display_short)|uniprotkb:CG9623(orf name)|uniprotkb:Position-specific antigen subunit alpha-2(gene name synonym)|uniprotkb:Protein inflated(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873338 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001285670.1|refseq:NP_477033.1|flybase:FBgn0011722|ensemblmetazoa:FBgn0011722(gene)|ensemblmetazoa:FBtr0079275(transcript)|ensemblmetazoa:FBtr0343152(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0072499"(photoreceptor cell axon guidance)|interpro:IPR016084(Haem oxygenase-like, multi-helical) refseq:NP_728021.2|refseq:NP_001162777.1|refseq:NP_001162778.1|refseq:NP_523378.2|flybase:FBgn0001250|dip:DIP-23111N|ensemblmetazoa:FBgn0001250(gene)|ensemblmetazoa:FBtr0074357(transcript)|ensemblmetazoa:FBtr0301353(transcript)|ensemblmetazoa:FBtr0301354(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007411"(axon guidance)|go:"GO:0007414"(axonal defasciculation)|go:"GO:0007419"(ventral cord development)|go:"GO:0007431"(salivary gland development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007475"(apposition of dorsal and ventral imaginal disc-derived wing surfaces)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008305"(integrin complex)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021551"(central nervous system morphogenesis)|go:"GO:0030239"(myofibril assembly)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0042383"(sarcolemma)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|reactome:R-DME-1566977|reactome:R-DME-198933|reactome:R-DME-202733|reactome:R-DME-2129379|reactome:R-DME-216083|reactome:R-DME-3000157|reactome:R-DME-3000170|reactome:R-DME-3000178|reactome:R-DME-354192|reactome:R-DME-5674135|reactome:R-DME-6798695 pubmed:7972082(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:9lQuCrQ/U4TzUezweIpodaD1fwQ7227 rogid:srwsUuxnXhFxPinl41xbr5x8g207227 intact-crc:3C27C914D9A68C6A|rigid:eQWGS1hiqsT76RALqNmUG7K/sn8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O61307 uniprotkb:P12080 intact:EBI-118556|ensemblmetazoa:FBpp0078161|intact:EBI-9921296|intact:EBI-6405206|intact:EBI-3417376|intact:EBI-869833|uniprotkb:A8JNW8|uniprotkb:O18366|uniprotkb:Q24551|uniprotkb:Q9TX59|uniprotkb:Q9VNU6 intact:EBI-259113|uniprotkb:Q9VXB6|intact:EBI-9925499|intact:EBI-3415358|uniprotkb:E1JJN2|uniprotkb:Q8IR07|uniprotkb:Q8MSG3|ensemblmetazoa:FBpp0074131|ensemblmetazoa:FBpp0290567|ensemblmetazoa:FBpp0290568 psi-mi:tenm_drome(display_long)|uniprotkb:Ten-m(gene name)|psi-mi:Ten-m(display_short)|uniprotkb:Odd Oz protein(gene name synonym)|uniprotkb:Tenascin-like protein(gene name synonym)|uniprotkb:odz(gene name synonym)|uniprotkb:CG5723(orf name) psi-mi:ita2_drome(display_long)|uniprotkb:if(gene name)|psi-mi:if(display_short)|uniprotkb:CG9623(orf name)|uniprotkb:Position-specific antigen subunit alpha-2(gene name synonym)|uniprotkb:Protein inflated(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873342 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0004449|refseq:NP_001097661.2|refseq:NP_524215.2|ensemblmetazoa:FBgn0004449(gene)|ensemblmetazoa:FBtr0078509(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0016200"(synaptic target attraction)|go:"GO:0022416"(chaeta development)|go:"GO:0031005"(filamin binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034110"(regulation of homotypic cell-cell adhesion)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045467"(R7 cell development)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048058"(compound eye corneal lens development)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0050808"(synapse organization)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0097090"(presynaptic membrane organization)|go:"GO:0099190"(postsynaptic spectrin-associated cytoskeleton organization)|go:"GO:0099559"(maintenance of alignment of postsynaptic density and presynaptic active zone)|go:"GO:2000331"(regulation of terminal button organization)|go:"GO:0001745"(compound eye morphogenesis)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR006530(YD repeat)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR028916|interpro:IPR031325|go:"GO:0001941"(postsynaptic membrane organization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane) refseq:NP_728021.2|refseq:NP_001162777.1|refseq:NP_001162778.1|refseq:NP_523378.2|flybase:FBgn0001250|dip:DIP-23111N|ensemblmetazoa:FBgn0001250(gene)|ensemblmetazoa:FBtr0074357(transcript)|ensemblmetazoa:FBtr0301353(transcript)|ensemblmetazoa:FBtr0301354(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007411"(axon guidance)|go:"GO:0007414"(axonal defasciculation)|go:"GO:0007419"(ventral cord development)|go:"GO:0007431"(salivary gland development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007475"(apposition of dorsal and ventral imaginal disc-derived wing surfaces)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008305"(integrin complex)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021551"(central nervous system morphogenesis)|go:"GO:0030239"(myofibril assembly)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0042383"(sarcolemma)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|reactome:R-DME-1566977|reactome:R-DME-198933|reactome:R-DME-202733|reactome:R-DME-2129379|reactome:R-DME-216083|reactome:R-DME-3000157|reactome:R-DME-3000170|reactome:R-DME-3000178|reactome:R-DME-354192|reactome:R-DME-5674135|reactome:R-DME-6798695 pubmed:9660786(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:fQRGDVAakYq/Zy5noZyJEeDgrQY7227 rogid:srwsUuxnXhFxPinl41xbr5x8g207227 intact-crc:4524B529DAF2BD20|rigid:YZwyfFcZMzngT90BzHadH84b/wo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10676 uniprotkb:P13677 intact:EBI-674492|uniprotkb:P10677|uniprotkb:Q8MRP1|uniprotkb:Q9VM23|uniprotkb:Q9VM24|ensemblmetazoa:FBpp0079064 intact:EBI-130595|uniprotkb:Q9V7V5|ensemblmetazoa:FBpp0086196 psi-mi:ninac_drome(display_long)|uniprotkb:ninaC(gene name)|psi-mi:ninaC(display_short)|uniprotkb:CG5125(orf name) psi-mi:kpc2_drome(display_long)|uniprotkb:inaC(gene name)|psi-mi:inaC(display_short)|uniprotkb:PKC2(gene name synonym)|uniprotkb:CG6518(orf name)|uniprotkb:Eye-PKC(gene name synonym)|uniprotkb:Photoreceptor-specific PKC(gene name synonym)|uniprotkb:"dPKC53E(EY)"(gene name synonym)|uniprotkb:Inactivation no after-potential C protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873346 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523503.2|refseq:NP_723271.1|flybase:FBgn0002938|refseq:NP_001260189.1|refseq:NP_001260190.1|interpro:IPR036961|ensemblmetazoa:FBgn0002938(gene)|ensemblmetazoa:FBtr0079436(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0007604"(phototransduction, UV)|go:"GO:0008104"(protein localization)|go:"GO:0009416"(response to light stimulus)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0033227"(dsRNA transport)|go:"GO:0033583"(rhabdomere membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042385"(myosin III complex)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990146"(protein localization to rhabdomere)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020635|interpro:IPR027417 refseq:NP_476863.1|flybase:FBgn0004784|ensemblmetazoa:FBgn0004784(gene)|ensemblmetazoa:FBtr0087047(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008585"(female gonad development)|go:"GO:0009416"(response to light stimulus)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030845"(phospholipase C-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045471"(response to ethanol)|go:"GO:0050962"(detection of light stimulus involved in sensory perception)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR035892|reactome:R-DME-111933|reactome:R-DME-114516|reactome:R-DME-1169091|reactome:R-DME-4419969|reactome:R-DME-5099900|reactome:R-DME-5218921|reactome:R-DME-76005|dip:DIP-54N pubmed:9822721(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:igNic9r58X1xxPMXgTE4sUFkwkE7227 rogid:foe+SbTNOE16H0jrxgDbyAGKxHk7227 intact-crc:50BB12D8514BF82B|rigid:MLRd77beM0Ld8jEsLFnmJoHRBD8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24008 uniprotkb:P13677 intact:EBI-195326|uniprotkb:Q9NBV3|ensemblmetazoa:FBpp0071820 intact:EBI-130595|uniprotkb:Q9V7V5|ensemblmetazoa:FBpp0086196 psi-mi:inad_drome(display_long)|uniprotkb:inaD(gene name)|psi-mi:inaD(display_short)|uniprotkb:CG3504(orf name) psi-mi:kpc2_drome(display_long)|uniprotkb:inaC(gene name)|psi-mi:inaC(display_short)|uniprotkb:PKC2(gene name synonym)|uniprotkb:CG6518(orf name)|uniprotkb:Eye-PKC(gene name synonym)|uniprotkb:Photoreceptor-specific PKC(gene name synonym)|uniprotkb:"dPKC53E(EY)"(gene name synonym)|uniprotkb:Inactivation no after-potential C protein(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873350 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_726260.1|flybase:FBgn0001263|dip:DIP-18621N|ensemblmetazoa:FBgn0001263(gene)|ensemblmetazoa:FBtr0071909(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008104"(protein localization)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0017022"(myosin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031473"(myosin III binding)|go:"GO:0050962"(detection of light stimulus involved in sensory perception)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rcsb pdb:1IHJ|rcsb pdb:2LA8|rcsb pdb:2QKT|rcsb pdb:2QKU|rcsb pdb:2QKV|rcsb pdb:3R0H|rcsb pdb:5F67|rcsb pdb:6IRE|reactome:R-DME-983168 refseq:NP_476863.1|flybase:FBgn0004784|ensemblmetazoa:FBgn0004784(gene)|ensemblmetazoa:FBtr0087047(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008585"(female gonad development)|go:"GO:0009416"(response to light stimulus)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0016062"(adaptation of rhodopsin mediated signaling)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030845"(phospholipase C-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045471"(response to ethanol)|go:"GO:0050962"(detection of light stimulus involved in sensory perception)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR035892|reactome:R-DME-111933|reactome:R-DME-114516|reactome:R-DME-1169091|reactome:R-DME-4419969|reactome:R-DME-5099900|reactome:R-DME-5218921|reactome:R-DME-76005|dip:DIP-54N pubmed:9651370(see-also)|pubmed:9679151(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:A8GcGpwkZoLFwA/GoYkveOsUzC07227 rogid:foe+SbTNOE16H0jrxgDbyAGKxHk7227 intact-crc:A0716E14886392E3|rigid:krhcjrYCf9NJ3fNG8XT18D/yV0U false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P48994 uniprotkb:Q24008 intact:EBI-98143|uniprotkb:Q0E9E3|uniprotkb:Q8IH62|uniprotkb:Q8MKU9|uniprotkb:Q9V5B2|intact:EBI-3407987|uniprotkb:C6TPC1|ensemblmetazoa:FBpp0087555|ensemblmetazoa:FBpp0087557|ensemblmetazoa:FBpp0290876 intact:EBI-195326|uniprotkb:Q9NBV3|ensemblmetazoa:FBpp0071820 psi-mi:trpl_drome(display_long)|uniprotkb:trpl(gene name)|psi-mi:trpl(display_short)|uniprotkb:CG18345(orf name) psi-mi:inad_drome(display_long)|uniprotkb:inaD(gene name)|psi-mi:inaD(display_short)|uniprotkb:CG3504(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873354 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476895.1|refseq:NP_724822.1|refseq:NP_724823.2|flybase:FBgn0005614|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071454"(cellular response to anoxia)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-114508|reactome:R-DME-139853|reactome:R-DME-3295583|reactome:R-DME-5578775|reactome:R-DME-983695|ensemblmetazoa:FBgn0005614(gene)|ensemblmetazoa:FBtr0088471(transcript)|ensemblmetazoa:FBtr0088473(transcript)|ensemblmetazoa:FBtr0301662(transcript)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006828"(manganese ion transport)|go:"GO:0007589"(body fluid secretion)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010461"(light-activated ion channel activity)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0034703"(cation channel complex)|go:"GO:0035997"(rhabdomere microvillus membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070588"(calcium ion transmembrane transport) refseq:NP_726260.1|flybase:FBgn0001263|dip:DIP-18621N|ensemblmetazoa:FBgn0001263(gene)|ensemblmetazoa:FBtr0071909(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008104"(protein localization)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0017022"(myosin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031473"(myosin III binding)|go:"GO:0050962"(detection of light stimulus involved in sensory perception)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rcsb pdb:1IHJ|rcsb pdb:2LA8|rcsb pdb:2QKT|rcsb pdb:2QKU|rcsb pdb:2QKV|rcsb pdb:3R0H|rcsb pdb:5F67|rcsb pdb:6IRE|reactome:R-DME-983168 pubmed:9679151(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:glMABf53+ZJj3aUROdZNs7ts6Bc7227 rogid:A8GcGpwkZoLFwA/GoYkveOsUzC07227 intact-crc:F0420BF20B1130D2|rigid:XsKQvw5oMhPZxRkXNDIC+h12j3I false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P19334 uniprotkb:Q24008 intact:EBI-165136|uniprotkb:Q7YU76|uniprotkb:Q9VAE1|ensemblmetazoa:FBpp0084879 intact:EBI-195326|uniprotkb:Q9NBV3|ensemblmetazoa:FBpp0071820 psi-mi:trp_drome(display_long)|uniprotkb:trp(gene name)|psi-mi:trp(display_short)|uniprotkb:CG7875(orf name) psi-mi:inad_drome(display_long)|uniprotkb:inaD(gene name)|psi-mi:inaD(display_short)|uniprotkb:CG3504(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873358 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476768.1|flybase:FBgn0003861|ensemblmetazoa:FBgn0003861(gene)|ensemblmetazoa:FBtr0085513(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006828"(manganese ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007602"(phototransduction)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008104"(protein localization)|go:"GO:0008355"(olfactory learning)|go:"GO:0008377"(light-induced release of internally sequestered calcium ion)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010461"(light-activated ion channel activity)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0034703"(cation channel complex)|go:"GO:0035997"(rhabdomere microvillus membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0050962"(detection of light stimulus involved in sensory perception)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:0098662"(inorganic cation transmembrane transport)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:5F67|rcsb pdb:7CQH|rcsb pdb:7CQV|reactome:R-DME-114508|reactome:R-DME-139853|reactome:R-DME-3295583|reactome:R-DME-5578775|reactome:R-DME-983695 refseq:NP_726260.1|flybase:FBgn0001263|dip:DIP-18621N|ensemblmetazoa:FBgn0001263(gene)|ensemblmetazoa:FBtr0071909(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008104"(protein localization)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0017022"(myosin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031473"(myosin III binding)|go:"GO:0050962"(detection of light stimulus involved in sensory perception)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rcsb pdb:1IHJ|rcsb pdb:2LA8|rcsb pdb:2QKT|rcsb pdb:2QKU|rcsb pdb:2QKV|rcsb pdb:3R0H|rcsb pdb:5F67|rcsb pdb:6IRE|reactome:R-DME-983168 pubmed:10995445(see-also)|pubmed:11150331(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:CZ/nZUylQKoS0GQ3jKaucCw8gjo7227 rogid:A8GcGpwkZoLFwA/GoYkveOsUzC07227 intact-crc:7688DEE3D591AADD|rigid:yKZ8+as1sCVyTMyv69MfpUkf70o false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24008 uniprotkb:P08099 intact:EBI-195326|uniprotkb:Q9NBV3|ensemblmetazoa:FBpp0071820 intact:EBI-162315|uniprotkb:Q9VE29|ensemblmetazoa:FBpp0083111 psi-mi:inad_drome(display_long)|uniprotkb:inaD(gene name)|psi-mi:inaD(display_short)|uniprotkb:CG3504(orf name) psi-mi:ops2_drome(display_long)|uniprotkb:Rh2(gene name)|psi-mi:Rh2(display_short)|uniprotkb:CG16740(orf name)|uniprotkb:Ocellar opsin(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873362 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_726260.1|flybase:FBgn0001263|dip:DIP-18621N|ensemblmetazoa:FBgn0001263(gene)|ensemblmetazoa:FBtr0071909(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008104"(protein localization)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0017022"(myosin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031473"(myosin III binding)|go:"GO:0050962"(detection of light stimulus involved in sensory perception)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rcsb pdb:1IHJ|rcsb pdb:2LA8|rcsb pdb:2QKT|rcsb pdb:2QKU|rcsb pdb:2QKV|rcsb pdb:3R0H|rcsb pdb:5F67|rcsb pdb:6IRE|reactome:R-DME-983168 refseq:NP_524398.1|flybase:FBgn0003248|ensemblmetazoa:FBgn0003248(gene)|ensemblmetazoa:FBtr0083697(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018298"(protein-chromophore linkage)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001735(Opsin RH1/RH2)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR027430|dip:DIP-22447N pubmed:11500369(see-also)|pubmed:12238768(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:A8GcGpwkZoLFwA/GoYkveOsUzC07227 rogid:wupEQruy/r60f/UvVvmuD8AyaGg7227 intact-crc:2DE1E1DE36790094|rigid:4Qf/DAvUleW5OquIBaUSwVfudFU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P06002 uniprotkb:Q24008 intact:EBI-100064|uniprotkb:Q9TX56|ensemblmetazoa:FBpp0083266|uniprotkb:Q9VDS8|uniprotkb:A0AVV9|uniprotkb:Q4QPQ2 intact:EBI-195326|uniprotkb:Q9NBV3|ensemblmetazoa:FBpp0071820 psi-mi:ops1_drome(display_long)|uniprotkb:ninaE(gene name)|psi-mi:ninaE(display_short)|uniprotkb:Rh1(gene name synonym)|uniprotkb:CG4550(orf name)|uniprotkb:Outer R1-R6 photoreceptor cells opsin(gene name synonym)|uniprotkb:Neither inactivation nor afterpotential E protein(gene name synonym) psi-mi:inad_drome(display_long)|uniprotkb:inaD(gene name)|psi-mi:inaD(display_short)|uniprotkb:CG3504(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873366 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524407.1|flybase:FBgn0002940|ensemblmetazoa:FBgn0002940(gene)|ensemblmetazoa:FBtr0083857(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005769"(early endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009584"(detection of visible light)|go:"GO:0009589"(detection of UV)|go:"GO:0009642"(response to light intensity)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0016029"(subrhabdomeral cisterna)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030265"(phospholipase C-activating rhodopsin mediated signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042331"(phototaxis)|go:"GO:0043052"(thermotaxis)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0071632"(optomotor response)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001735(Opsin RH1/RH2)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR027430|mint:P06002|dip:DIP-17500N refseq:NP_726260.1|flybase:FBgn0001263|dip:DIP-18621N|ensemblmetazoa:FBgn0001263(gene)|ensemblmetazoa:FBtr0071909(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008104"(protein localization)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0016059"(deactivation of rhodopsin mediated signaling)|go:"GO:0017022"(myosin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031473"(myosin III binding)|go:"GO:0050962"(detection of light stimulus involved in sensory perception)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rcsb pdb:1IHJ|rcsb pdb:2LA8|rcsb pdb:2QKT|rcsb pdb:2QKU|rcsb pdb:2QKV|rcsb pdb:3R0H|rcsb pdb:5F67|rcsb pdb:6IRE|reactome:R-DME-983168 pubmed:9679151(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:HJLSoXvFeTRzj6pgJKay21a6l3U7227 rogid:A8GcGpwkZoLFwA/GoYkveOsUzC07227 intact-crc:1AC3530DDC0778A4|rigid:8FTSKMj48kYowdhaXV2nuXAGf2s false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9NFR7 uniprotkb:Q24367 intact:EBI-497189 intact:EBI-868219 psi-mi:q9nfr7_drome(display_long)|uniprotkb:pins(gene name)|psi-mi:pins(display_short)|uniprotkb:raps(gene name synonym)|uniprotkb:CG5692(orf name) psi-mi:q24367_drome(display_long)|uniprotkb:insc(gene name)|psi-mi:insc(display_short)|uniprotkb:inscuteable(gene name synonym)|uniprotkb:CG11312(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873370 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0040080|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0055059"(asymmetric neuroblast division)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 flybase:FBgn0011674|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006403"(RNA localization)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008104"(protein localization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045176"(apical protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039921|rcsb pdb:5A7D pubmed:10693757(see-also)|pubmed:10753746(see-also)|pubmed:12024035(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:bJLhIKptzMvBzyui3OKrX5Ey3sw7227 rogid:gqUxZqIF4l7DUDBAs57rDl6o79U7227 intact-crc:DCCA30F4945DFD50|rigid:Mee6cIp8xBKi/k/4BCHH46hDtdI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P29617 uniprotkb:Q24367 intact:EBI-213350|uniprotkb:Q95SP0|uniprotkb:Q9U6A2|uniprotkb:Q9VGP8|uniprotkb:Q6AWI5|uniprotkb:A0A0B4K660|ensemblmetazoa:FBpp0293150 intact:EBI-868219 psi-mi:pros_drome(display_long)|uniprotkb:pros(gene name)|psi-mi:pros(display_short)|uniprotkb:CG17228(orf name) psi-mi:q24367_drome(display_long)|uniprotkb:insc(gene name)|psi-mi:insc(display_short)|uniprotkb:inscuteable(gene name synonym)|uniprotkb:CG11312(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873374 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001247046.1|refseq:NP_524317.4|refseq:NP_731565.4|refseq:NP_788636.3|flybase:FBgn0004595|ensemblmetazoa:FBgn0004595(gene)|ensemblmetazoa:FBtr0304608(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007402"(ganglion mother cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014016"(neuroblast differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045179"(apical cortex)|go:"GO:0045180"(basal cortex)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0055060"(asymmetric neuroblast division resulting in ganglion mother cell formation)|go:"GO:0060385"(axonogenesis involved in innervation)|go:"GO:0061564"(axon development)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070983"(dendrite guidance)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR009057(Homeodomain-like)|interpro:IPR023082|interpro:IPR037131|interpro:IPR039350|rcsb pdb:1MIJ|rcsb pdb:1XPX flybase:FBgn0011674|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006403"(RNA localization)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008104"(protein localization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045176"(apical protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039921|rcsb pdb:5A7D pubmed:10021388(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xphiJOfb887AalCF1YoE2OD0DcQ7227 rogid:gqUxZqIF4l7DUDBAs57rDl6o79U7227 intact-crc:09295F66CDB29BC3|rigid:ySmY+Nu/U2+wYmlskfVbae1a4tE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16554 uniprotkb:Q24367 intact:EBI-429581|uniprotkb:Q8IPE9|uniprotkb:Q961A6|uniprotkb:Q9VLB8|uniprotkb:B8A413|uniprotkb:B8A419|ensemblmetazoa:FBpp0079420|ensemblmetazoa:FBpp0308609 intact:EBI-868219 psi-mi:numb_drome(display_long)|uniprotkb:CG3779(orf name)|uniprotkb:numb(gene name)|psi-mi:numb(display_short) psi-mi:q24367_drome(display_long)|uniprotkb:insc(gene name)|psi-mi:insc(display_short)|uniprotkb:inscuteable(gene name synonym)|uniprotkb:CG11312(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873378 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523523.2|refseq:NP_723460.1|flybase:FBgn0002973|refseq:NP_001260291.1|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051642"(centrosome localization)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|mint:P16554|go:"GO:0045178"(basal part of cell)|rcsb pdb:1DDM|rcsb pdb:2NMB|rcsb pdb:5YI7|rcsb pdb:5YI8|reactome:R-DME-5610780|reactome:R-DME-5632684|ensemblmetazoa:FBgn0002973(gene)|ensemblmetazoa:FBtr0079822(transcript)|ensemblmetazoa:FBtr0339526(transcript)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005112"(Notch binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008104"(protein localization)|go:"GO:0008347"(glial cell migration)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0045035"(sensory organ precursor cell division) flybase:FBgn0011674|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006403"(RNA localization)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008104"(protein localization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045176"(apical protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039921|rcsb pdb:5A7D pubmed:10021388(see-also)|pubmed:10212148(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:9FGhbcAA6k1LCDHPoLSXwEEVwzY7227 rogid:gqUxZqIF4l7DUDBAs57rDl6o79U7227 intact-crc:EB313A6969D195E6|rigid:plmAI5r9baJhFlvDNm1nrLHOeCc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O44224 uniprotkb:Q24367 intact:EBI-869852 intact:EBI-868219 psi-mi:o44224_drome(display_long)|uniprotkb:mira(gene name)|psi-mi:mira(display_short)|uniprotkb:CG12249(orf name) psi-mi:q24367_drome(display_long)|uniprotkb:insc(gene name)|psi-mi:insc(display_short)|uniprotkb:inscuteable(gene name synonym)|uniprotkb:CG11312(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873382 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0021776|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005938"(cell cortex)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007402"(ganglion mother cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007419"(ventral cord development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045178"(basal part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045180"(basal cortex)|go:"GO:0048477"(oogenesis)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0072697"(protein localization to cell cortex) flybase:FBgn0011674|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006403"(RNA localization)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008104"(protein localization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045176"(apical protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039921|rcsb pdb:5A7D pubmed:9267025(see-also)|pubmed:9425348(see-also)|pubmed:9637685(see-also)|pubmed:10021388(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:BJlUYvSh2EVnA0PxNbeFipc/S207227 rogid:gqUxZqIF4l7DUDBAs57rDl6o79U7227 intact-crc:96968A6895CD6356|rigid:AJzATwbYeM03GWNJFTsxf8xrvp4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P12982 uniprotkb:O96723 intact:EBI-152633|uniprotkb:Q4PIY5|uniprotkb:Q9VG75|ensemblmetazoa:FBpp0082067 intact:EBI-869863 psi-mi:pp12_drome(display_long)|uniprotkb:Pp1-87B(gene name)|psi-mi:Pp1-87B(display_short)|uniprotkb:CG5650(orf name) psi-mi:o96723_drome(display_long)|uniprotkb:I-t(gene name)|psi-mi:I-t(display_short)|uniprotkb:Inhibitor-t(gene name synonym)|uniprotkb:CG14719(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873386 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524937.1|flybase:FBgn0004103|ensemblmetazoa:FBgn0004103(gene)|ensemblmetazoa:FBtr0082595(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007611"(learning or memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008355"(olfactory learning)|go:"GO:0008542"(visual learning)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030261"(chromosome condensation)|go:"GO:0040011"(locomotion)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|go:"GO:0005737"(cytoplasm)|reactome:R-DME-350416|reactome:R-DME-350480|reactome:R-DME-538898|go:"GO:0005700"(polytene chromosome)|dip:DIP-18465N flybase:FBgn0025821|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0035308"(negative regulation of protein dephosphorylation) pubmed:9821974(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:wYZDYWZEbdafO7gAM+avnFnIF9Q7227 rogid:yoNLko0ic/J4a28nKOWZ6wcfYrw7227 intact-crc:6BA5B2F1B56D18FA|rigid:tBHk/o7J/9ao6qBdEV/28yIFzug false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24306 uniprotkb:Q9V3Q4 intact:EBI-456419|uniprotkb:A4V1Z9|uniprotkb:Q0E8E4|uniprotkb:Q8MRM5|uniprotkb:Q9VUX5|uniprotkb:A9UN33|ensemblmetazoa:FBpp0075254|ensemblmetazoa:FBpp0075255|ensemblmetazoa:FBpp0075256|ensemblmetazoa:FBpp0305793|ensemblmetazoa:FBpp0305794|ensemblmetazoa:FBpp0305795 intact:EBI-136438|ensemblmetazoa:FBpp0072852|ensemblmetazoa:FBpp0072853|ensemblmetazoa:FBpp0304422 psi-mi:diap1_drome(display_long)|uniprotkb:Diap1(gene name)|psi-mi:Diap1(display_short)|uniprotkb:Apoptosis 1 inhibitor(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase th(gene name synonym)|uniprotkb:Iap1(gene name synonym)|uniprotkb:Inhibitor of apoptosis 1(gene name synonym)|uniprotkb:Protein thread(gene name synonym)|uniprotkb:th(gene name synonym)|uniprotkb:CG12284(orf name)|uniprotkb:RING-type E3 ubiquitin transferase Diap1(gene name synonym) psi-mi:q9v3q4_drome(display_long)|uniprotkb:Jafrac2(gene name)|psi-mi:Jafrac2(display_short)|uniprotkb:1274(gene name synonym)|uniprotkb:DPx-4156(gene name synonym)|uniprotkb:DPx4156(gene name synonym)|uniprotkb:Dmel\CG1274(gene name synonym)|uniprotkb:JafRac2(gene name synonym)|uniprotkb:Jafrac(gene name synonym)|uniprotkb:Jafrac-2(gene name synonym)|uniprotkb:Prx4(gene name synonym)|uniprotkb:Prx4156(gene name synonym)|uniprotkb:dPrx4(gene name synonym)|uniprotkb:jafrac2(gene name synonym)|uniprotkb:Dmel_CG1274(orf name)|uniprotkb:CG1274(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873390 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524101.2|refseq:NP_730097.1|refseq:NP_730098.1|flybase:FBgn0260635|refseq:NP_001261916.1|refseq:NP_001261917.1|refseq:NP_001261918.1|go:"GO:0006915"(apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0022416"(chaeta development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0045116"(protein neddylation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|ensemblmetazoa:FBgn0260635(gene)|ensemblmetazoa:FBtr0075499(transcript)|ensemblmetazoa:FBtr0075500(transcript)|ensemblmetazoa:FBtr0075501(transcript)|ensemblmetazoa:FBtr0333617(transcript)|ensemblmetazoa:FBtr0333618(transcript)|ensemblmetazoa:FBtr0333619(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|mint:Q24306|rcsb pdb:1JD4|rcsb pdb:1JD5|rcsb pdb:1JD6|rcsb pdb:1Q4Q|rcsb pdb:1SDZ|rcsb pdb:1SE0|rcsb pdb:3SIP|rcsb pdb:3SIQ|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-3769402|reactome:R-DME-390150|reactome:R-DME-5675482|reactome:R-DME-8948747|reactome:R-DME-8948751 refseq:NP_525002.1|refseq:NP_728793.1|flybase:FBgn0040308|refseq:NP_001261350.1|ensemblmetazoa:FBgn0040308(gene)|ensemblmetazoa:FBtr0072982(transcript)|ensemblmetazoa:FBtr0072983(transcript)|ensemblmetazoa:FBtr0332112(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0012505"(endomembrane system)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0070417"(cellular response to cold)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|reactome:R-DME-6798695 pubmed:12356728(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:loBQ//cKQ1NYhq3gnIKwRBn5vZg7227 rogid:XcgC9jqN4GXjeJoBnFMXhebmUFk7227 intact-crc:897781E5C07C022C|rigid:0d7ess/9zjo/kyPf+C+flSWQ7uo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42283 uniprotkb:Q9V3I5 intact:EBI-869872|uniprotkb:Q54A11|uniprotkb:Q9V5M2|intact:EBI-3415560|ensemblmetazoa:FBpp0088381|ensemblmetazoa:FBpp0088391 intact:EBI-84939|uniprotkb:Q0E8F9|uniprotkb:Q95RY3|uniprotkb:B5RJL0|ensemblmetazoa:FBpp0075965|ensemblmetazoa:FBpp0075966|ensemblmetazoa:FBpp0304953|intact:EBI-3425957 psi-mi:lola1_drome(display_long)|uniprotkb:lola(gene name)|psi-mi:lola(display_short)|uniprotkb:CG12052(orf name) psi-mi:jil1_drome(display_long)|uniprotkb:JIL-1(gene name)|psi-mi:JIL-1(display_short)|uniprotkb:CG6297(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873394 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524766.2|refseq:NP_788312.2|flybase:FBgn0283521|ensemblmetazoa:FBgn0283521(gene)|ensemblmetazoa:FBtr0089347(transcript)|ensemblmetazoa:FBtr0089357(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008406"(gonad development)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0045467"(R7 cell development)|go:"GO:0045476"(nurse cell apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048813"(dendrite morphogenesis)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 refseq:NP_648432.1|refseq:NP_729661.1|flybase:FBgn0020412|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|ensemblmetazoa:FBgn0020412(gene)|ensemblmetazoa:FBtr0076236(transcript)|ensemblmetazoa:FBtr0076237(transcript)|go:"GO:0016456"(X chromosome located dosage compensation complex, transcription activating)|ensemblmetazoa:FBtr0332707(transcript)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035175"("histone kinase activity (H3-S10 specific)")|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0048477"(oogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0000723"(telomere maintenance)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|reactome:R-DME-198753|reactome:R-DME-199920|reactome:R-DME-375165|reactome:R-DME-5621575|refseq:NP_001261697.1 pubmed:12538650(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:weHOCGBLH7iSAw9DnPetQaJkntg7227 rogid:NrVAOLnNFXZIoU33rJh/iIiWKZ87227 intact-crc:7B0C7A47A0B60D61|rigid:Cxd85By2Xp89HIYACbYVlbPdT7A false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P51023 uniprotkb:P18289 intact:EBI-154079|uniprotkb:B9EQV8|uniprotkb:Q29R53|uniprotkb:Q8IG92|uniprotkb:Q9VCN2|uniprotkb:Q8IMZ1|intact:EBI-870003|uniprotkb:A0A0B4KH96|uniprotkb:H8F4R1|uniprotkb:P19420|uniprotkb:P51022|ensemblmetazoa:FBpp0088658 intact:EBI-159948|uniprotkb:Q0E9D8|ensemblmetazoa:FBpp0087498|ensemblmetazoa:FBpp0087499|uniprotkb:Q9V5G4 psi-mi:pnt_drome(display_long)|uniprotkb:pnt(gene name)|psi-mi:pnt(display_short)|uniprotkb:ETS2(gene name synonym)|uniprotkb:Ets58AB(gene name synonym)|uniprotkb:DMPOINT1A(gene name synonym)|uniprotkb:pointed(gene name synonym)|uniprotkb:CG17077(orf name) psi-mi:jra_drome(display_long)|uniprotkb:Jra(gene name)|psi-mi:Jra(display_short)|uniprotkb:jun(gene name synonym)|uniprotkb:CG2275(orf name)|uniprotkb:Jun-related antigen(gene name synonym)|uniprotkb:dJRA(gene name synonym)|uniprotkb:dJun(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873398 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524461.2|refseq:NP_732857.1|flybase:FBgn0003118|ensemblmetazoa:FBgn0003118(gene)|ensemblmetazoa:FBtr0089717(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001742"(oenocyte differentiation)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009997"(negative regulation of cardioblast cell fate specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035154"(terminal cell fate specification, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0007428"(primary branching, open tracheal system)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0007429"(secondary branching, open tracheal system)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0055001"(muscle cell development)|go:"GO:0060438"(trachea development)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|mint:P51023|reactome:R-DME-2559585|go:"GO:0043697"(cell dedifferentiation)|dip:DIP-19576N|refseq:NP_001262872.1|refseq:NP_732858.1 refseq:NP_476586.1|refseq:NP_724882.1|flybase:FBgn0001291|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029823|reactome:R-DME-209394|reactome:R-DME-2559580|reactome:R-DME-209409|reactome:R-DME-2871796|reactome:R-DME-450341|reactome:R-DME-209425|ensemblmetazoa:FBgn0001291(gene)|ensemblmetazoa:FBtr0088410(transcript)|ensemblmetazoa:FBtr0088411(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007254"(JNK cascade)|go:"GO:0007391"(dorsal closure)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0008348"(negative regulation of antimicrobial humoral response)|go:"GO:0010259"(multicellular organism aging)|dip:DIP-18982N pubmed:8521492(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2018/07/05 rogid:CHksMmvAXZCAMhi61vR2ZtWY5aQ7227 rogid:2mZFIBFRb3iqZpVcG9UScYWj/I47227 intact-crc:3114F93B3D2FA453|rigid:Mwye45WLPSsL/d9+DUkBnEuyBPI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P21525 uniprotkb:P18289 intact:EBI-195448|uniprotkb:Q400M6|uniprotkb:Q400M7|uniprotkb:Q53YJ8|uniprotkb:A8MPI0|uniprotkb:Q8T9E2|uniprotkb:Q9BH37|uniprotkb:Q9NBW7|uniprotkb:Q9VAH5|ensemblmetazoa:FBpp0288515 intact:EBI-159948|uniprotkb:Q0E9D8|ensemblmetazoa:FBpp0087498|ensemblmetazoa:FBpp0087499|uniprotkb:Q9V5G4 psi-mi:fosla_drome(display_long)|uniprotkb:kay(gene name)|psi-mi:kay(display_short)|uniprotkb:Fra(gene name synonym)|uniprotkb:CG15509(orf name)|uniprotkb:Fos-related antigen(gene name synonym)|uniprotkb:AP-1(gene name synonym) psi-mi:jra_drome(display_long)|uniprotkb:Jra(gene name)|psi-mi:Jra(display_short)|uniprotkb:jun(gene name synonym)|uniprotkb:CG2275(orf name)|uniprotkb:Jun-related antigen(gene name synonym)|uniprotkb:dJRA(gene name synonym)|uniprotkb:dJun(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873402 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027577.2|refseq:NP_001027578.1|refseq:NP_001027579.1|flybase:FBgn0001297|dip:DIP-22245N|ensemblmetazoa:FBgn0001297(gene)|ensemblmetazoa:FBtr0290076(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006964"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007281"(germ cell development)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0009611"(response to wounding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0035220"(wing disc development)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042060"(wound healing)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048674"(collateral sprouting of injured axon)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|reactome:R-DME-209394|reactome:R-DME-209409|reactome:R-DME-209425|reactome:R-DME-2559580|reactome:R-DME-2871796|reactome:R-DME-450341 refseq:NP_476586.1|refseq:NP_724882.1|flybase:FBgn0001291|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029823|reactome:R-DME-209394|reactome:R-DME-2559580|reactome:R-DME-209409|reactome:R-DME-2871796|reactome:R-DME-450341|reactome:R-DME-209425|ensemblmetazoa:FBgn0001291(gene)|ensemblmetazoa:FBtr0088410(transcript)|ensemblmetazoa:FBtr0088411(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007254"(JNK cascade)|go:"GO:0007391"(dorsal closure)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0008348"(negative regulation of antimicrobial humoral response)|go:"GO:0010259"(multicellular organism aging)|dip:DIP-18982N pubmed:2116361(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:P1VNgVJTLHiW0Qxi4IeXzf0fWDw7227 rogid:2mZFIBFRb3iqZpVcG9UScYWj/I47227 intact-crc:8413B0C4A10D93F4|rigid:a0WBFcopfVv1P8BSVcrmdcOclMQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40417 uniprotkb:P21525 intact:EBI-867790|uniprotkb:A0A021WW06|uniprotkb:Q7PL59|uniprotkb:Q9W5M2|uniprotkb:A8Y4W1|uniprotkb:A8Y4W2|uniprotkb:Q9W5M3|ensemblmetazoa:FBpp0112423|ensemblmetazoa:FBpp0112425|ensemblmetazoa:FBpp0112426|ensemblmetazoa:FBpp0311493 intact:EBI-195448|uniprotkb:Q400M6|uniprotkb:Q400M7|uniprotkb:Q53YJ8|uniprotkb:A8MPI0|uniprotkb:Q8T9E2|uniprotkb:Q9BH37|uniprotkb:Q9NBW7|uniprotkb:Q9VAH5|ensemblmetazoa:FBpp0288515 psi-mi:erka_drome(display_long)|uniprotkb:Extracellular-regulated kinase A(gene name synonym)|uniprotkb:Protein rolled(gene name synonym)|uniprotkb:rl(gene name)|psi-mi:rl(display_short)|uniprotkb:ERKa(gene name synonym)|uniprotkb:CG12559(orf name)|uniprotkb:MAPK(gene name synonym) psi-mi:fosla_drome(display_long)|uniprotkb:kay(gene name)|psi-mi:kay(display_short)|uniprotkb:Fra(gene name synonym)|uniprotkb:CG15509(orf name)|uniprotkb:Fos-related antigen(gene name synonym)|uniprotkb:AP-1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873406 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001015121.3|refseq:NP_001104348.2|refseq:NP_001287635.1|refseq:NP_001015122.1|refseq:NP_001015123.1|refseq:NP_001104349.1|flybase:FBgn0003256|dip:DIP-17266N|ensemblmetazoa:FBgn0003256(gene)|ensemblmetazoa:FBtr0113700(transcript)|ensemblmetazoa:FBtr0113702(transcript)|ensemblmetazoa:FBtr0113703(transcript)|ensemblmetazoa:FBtr0345337(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007362"(terminal region determination)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000826"(regulation of heart morphogenesis)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P40417|reactome:R-DME-110056|reactome:R-DME-112409|reactome:R-DME-112411|reactome:R-DME-1295596|reactome:R-DME-162658|reactome:R-DME-170968|reactome:R-DME-198753|reactome:R-DME-202670|reactome:R-DME-2029482|reactome:R-DME-2559580|reactome:R-DME-2559582|reactome:R-DME-2559585|reactome:R-DME-2871796|reactome:R-DME-3371453|reactome:R-DME-375165|reactome:R-DME-437239|reactome:R-DME-445144|reactome:R-DME-450341|reactome:R-DME-456926|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5654733|reactome:R-DME-5663213|reactome:R-DME-5673001|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5687128|reactome:R-DME-6798695|reactome:R-DME-74749|reactome:R-DME-881907|reactome:R-DME-9634635|reactome:R-DME-9634638 refseq:NP_001027577.2|refseq:NP_001027578.1|refseq:NP_001027579.1|flybase:FBgn0001297|dip:DIP-22245N|ensemblmetazoa:FBgn0001297(gene)|ensemblmetazoa:FBtr0290076(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006964"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007281"(germ cell development)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0009611"(response to wounding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0035220"(wing disc development)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042060"(wound healing)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048674"(collateral sprouting of injured axon)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|reactome:R-DME-209394|reactome:R-DME-209409|reactome:R-DME-209425|reactome:R-DME-2559580|reactome:R-DME-2871796|reactome:R-DME-450341 pubmed:11410534(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:m7w7KhuZSyx3t+dR2TKtvx/vRtA7227 rogid:P1VNgVJTLHiW0Qxi4IeXzf0fWDw7227 intact-crc:3835DBF58D8234DA|rigid:TtJBQCQZtKH6rskn5t1H40XUeac false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8T0S7 uniprotkb:P17210 intact:EBI-870039 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 psi-mi:q8t0s7_drome(display_long)|uniprotkb:Unc-76(gene name)|psi-mi:Unc-76(display_short)|uniprotkb:CG3981(orf name) psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873410 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0040395|go:"GO:0005737"(cytoplasm)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030424"(axon) refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N pubmed:12925768(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:L008dmKy3XlWdkOuYVhnL7N0uXg7227 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 intact-crc:57A4BEE9449CA58B|rigid:BORfGnWvpGKZt18iisrmZmHv4s0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18105 uniprotkb:P17210 intact:EBI-87949|uniprotkb:Q9VYW9|ensemblmetazoa:FBpp0309258|ensemblmetazoa:FBpp0073363 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 psi-mi:nod_drome(display_long)|uniprotkb:nod(gene name)|psi-mi:nod(display_short)|uniprotkb:NODA(gene name synonym)|uniprotkb:CG1763(orf name) psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873414 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBtr0073516(transcript)|ensemblmetazoa:FBtr0340297(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008017"(microtubule binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032837"(distributive segregation)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|rcsb pdb:3DC4|rcsb pdb:3DCB|rcsb pdb:3DCO|rcsb pdb:3PXN|go:"GO:0051296"(establishment of meiotic spindle orientation)|ensemblmetazoa:FBgn0002948(gene)|refseq:NP_511125.2|flybase:FBgn0002948|refseq:NP_001285129.1|dip:DIP-22708N refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N pubmed:11739796(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:um8oDE5yfJBv3Cq57K1gtZZVTOI7227 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 intact-crc:10B91137C953CB1C|rigid:aILlZLzb1DgOA8e144wLp3IOiaI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P46824 uniprotkb:P17210 intact:EBI-77490|ensemblmetazoa:FBpp0075683|ensemblmetazoa:FBpp0303945|uniprotkb:Q9VU05 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 psi-mi:klc_drome(display_long)|uniprotkb:Klc(gene name)|psi-mi:Klc(display_short)|uniprotkb:CG5433(orf name) psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873418 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0010235(gene)|ensemblmetazoa:FBtr0075951(transcript)|ensemblmetazoa:FBtr0331555(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0046843"(dorsal appendage formation)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|reactome:R-DME-6811434|reactome:R-DME-983189|refseq:NP_524049.1|flybase:FBgn0010235|refseq:NP_001261780.1|dip:DIP-19091N refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N pubmed:9548722(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ggplfkjiCros+D00Q3kiqwGcRrE7227 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 intact-crc:BCB4171668412888|rigid:ZRqYwwKMBDviCIzWRPse9iaNTNY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P17210 uniprotkb:P17210 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 intact:EBI-102445|uniprotkb:Q9V7L9|ensemblmetazoa:FBpp0086328 psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:kinh_drome(display_long)|uniprotkb:Khc(gene name)|psi-mi:Khc(display_short)|uniprotkb:kin(gene name synonym)|uniprotkb:CG7765(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873422 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N refseq:NP_476590.1|flybase:FBgn0001308|ensemblmetazoa:FBgn0001308(gene)|ensemblmetazoa:FBtr0087184(transcript)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008345"(larval locomotory behavior)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030478"(actin cap)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051299"(centrosome separation)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:2Y5W|rcsb pdb:2Y65|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:7BJS|reactome:R-DME-6811434|reactome:R-DME-983189|dip:DIP-20367N pubmed:8206960(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 rogid:cRx8GAhruBKfSeUKt+moO6/OD+A7227 intact-crc:CD68CCF840FE5612|rigid:1aJ3PwY24BC+ZheTW3d4nD+cL7Q false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8WS23 uniprotkb:O97174 intact:EBI-870047 intact:EBI-869721 psi-mi:q8ws23_drome(display_long)|uniprotkb:rols(gene name)|psi-mi:rols(display_short)|uniprotkb:rols6(gene name synonym)|uniprotkb:CG32096(orf name) psi-mi:o97174_drome(display_long)|uniprotkb:kirre(gene name)|psi-mi:kirre(display_short)|uniprotkb:"EG:163A10.1"(gene name synonym)|uniprotkb:CG3653(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873426 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0041096|go:"GO:0005737"(cytoplasm)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016740"(transferase activity)|go:"GO:0030018"(Z disc)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0061327"(anterior Malpighian tubule development)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002110(Ankyrin)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770 flybase:FBgn0028369|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005917"(nephrocyte diaphragm)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007523"(larval visceral muscle development)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0036058"(filtration diaphragm assembly)|go:"GO:0036059"(nephrocyte diaphragm assembly)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0061321"(garland nephrocyte differentiation)|go:"GO:0097206"(nephrocyte filtration)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1901739"(regulation of myoblast fusion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179 pubmed:11709190(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:liZ6VBX2yzld6LPOkXv5Ro19rKY7227 rogid:+OQs2IWpBbhQza2pX+eCNpeFLYs7227 intact-crc:80F1314DCC46A1CC|rigid:xh24Ukpwqht9bsvXjBCsfe7Xxbw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07247 uniprotkb:P10734 intact:EBI-672843|uniprotkb:Q8SYW3|uniprotkb:Q9W0V9|ensemblmetazoa:FBpp0072351|ensemblmetazoa:FBpp0305365 intact:EBI-170297|intact:EBI-1630197|uniprotkb:Q540X6|uniprotkb:Q9VPC6|ensemblmetazoa:FBpp0077941 psi-mi:krup_drome(display_long)|uniprotkb:Kr(gene name)|psi-mi:Kr(display_short)|uniprotkb:CG3340(orf name) psi-mi:knir_drome(display_long)|uniprotkb:kni(gene name)|psi-mi:kni(display_short)|uniprotkb:NR0A1(gene name synonym)|uniprotkb:CG4717(orf name)|uniprotkb:Nuclear receptor subfamily 0 group A member 1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873430 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523867.1|flybase:FBgn0001325|refseq:NP_001261181.1|ensemblmetazoa:FBgn0001325(gene)|ensemblmetazoa:FBtr0072449(transcript)|ensemblmetazoa:FBtr0333162(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007517"(muscle organ development)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061332"(Malpighian tubule bud morphogenesis)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR031243|interpro:IPR036236 refseq:NP_524187.1|flybase:FBgn0001320|ensemblmetazoa:FBgn0001320(gene)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|ensemblmetazoa:FBtr0078283(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0008270"(zinc ion binding)|dip:DIP-17716N pubmed:7588607(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:r0X90GV+LseJkjX0mKqmA6xjcns7227 rogid:zPloouLNEALRKuLvtZc0jT4RZu07227 intact-crc:ED090F3A04426830|rigid:qmx3uWdRHKR49AvD6QPWv9nqVIA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O96881 uniprotkb:P07247 intact:EBI-176474|ensemblmetazoa:FBpp0073090 intact:EBI-672843|uniprotkb:Q8SYW3|uniprotkb:Q9W0V9|ensemblmetazoa:FBpp0072351|ensemblmetazoa:FBpp0305365 psi-mi:o96881_drome(display_long)|uniprotkb:TfIIEbeta(gene name)|psi-mi:TfIIEbeta(display_short)|uniprotkb:TfIIE-beta(gene name synonym)|uniprotkb:Dmel\CG1276(gene name synonym)|uniprotkb:E[[S]](gene name synonym)|uniprotkb:TFIIE(gene name synonym)|uniprotkb:TFIIEbeta(gene name synonym)|uniprotkb:TFIIbeta(gene name synonym)|uniprotkb:TfIIE(gene name synonym)|uniprotkb:dTFIIE-S(gene name synonym)|uniprotkb:dTFIIES(gene name synonym)|uniprotkb:Dmel_CG1276(orf name)|uniprotkb:CG1276(orf name) psi-mi:krup_drome(display_long)|uniprotkb:Kr(gene name)|psi-mi:Kr(display_short)|uniprotkb:CG3340(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873434 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523923.1|flybase:FBgn0015829|ensemblmetazoa:FBgn0015829(gene)|ensemblmetazoa:FBtr0073234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|interpro:IPR003166(Transcription factor TFIIE beta subunit, core)|interpro:IPR016656(Transcription initiation factor IIE, beta subunit)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040501|reactome:R-DME-674695|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 refseq:NP_523867.1|flybase:FBgn0001325|refseq:NP_001261181.1|ensemblmetazoa:FBgn0001325(gene)|ensemblmetazoa:FBtr0072449(transcript)|ensemblmetazoa:FBtr0333162(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007517"(muscle organ development)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061332"(Malpighian tubule bud morphogenesis)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR031243|interpro:IPR036236 pubmed:7753175(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:yw/WffMRusCfi/T9XmKG8uQENC47227 rogid:r0X90GV+LseJkjX0mKqmA6xjcns7227 intact-crc:7D9F9DCA381A028D|rigid:mm6N9BgdpfcrKUuD4v9glgfNppU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07247 uniprotkb:P29052 intact:EBI-672843|uniprotkb:Q8SYW3|uniprotkb:Q9W0V9|ensemblmetazoa:FBpp0072351|ensemblmetazoa:FBpp0305365 intact:EBI-107328|uniprotkb:Q6AWH9|uniprotkb:Q9VKV7|ensemblmetazoa:FBpp0079615|ensemblmetazoa:FBpp0305673 psi-mi:krup_drome(display_long)|uniprotkb:Kr(gene name)|psi-mi:Kr(display_short)|uniprotkb:CG3340(orf name) psi-mi:tf2b_drome(display_long)|uniprotkb:General transcription factor TFIIB(gene name synonym)|uniprotkb:TfIIB(gene name)|psi-mi:TfIIB(display_short)|uniprotkb:CG5193(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873438 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523867.1|flybase:FBgn0001325|refseq:NP_001261181.1|ensemblmetazoa:FBgn0001325(gene)|ensemblmetazoa:FBtr0072449(transcript)|ensemblmetazoa:FBtr0333162(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007517"(muscle organ development)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061332"(Malpighian tubule bud morphogenesis)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR031243|interpro:IPR036236 refseq:NP_001260349.1|refseq:NP_476888.1|flybase:FBgn0004915|dip:DIP-17603N|ensemblmetazoa:FBgn0004915(gene)|ensemblmetazoa:FBtr0080025(transcript)|ensemblmetazoa:FBtr0333489(transcript)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0070897"(transcription preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR000812(Transcription factor TFIIB related)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR013150(Transcription factor TFIIB, cyclin-related)|interpro:IPR013763(Cyclin-related)|interpro:IPR023486|interpro:IPR036915|reactome:R-DME-674695|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 pubmed:7753175(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:r0X90GV+LseJkjX0mKqmA6xjcns7227 rogid:elkTGn4p1gaBf5tseVuCRdSz4aM7227 intact-crc:1B4B46D60A0E8D5E|rigid:bGzVka3wjUB9Ni03k2niXMlfmwQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07247 uniprotkb:P07247 intact:EBI-672843|uniprotkb:Q8SYW3|uniprotkb:Q9W0V9|ensemblmetazoa:FBpp0072351|ensemblmetazoa:FBpp0305365 intact:EBI-672843|uniprotkb:Q8SYW3|uniprotkb:Q9W0V9|ensemblmetazoa:FBpp0072351|ensemblmetazoa:FBpp0305365 psi-mi:krup_drome(display_long)|uniprotkb:Kr(gene name)|psi-mi:Kr(display_short)|uniprotkb:CG3340(orf name) psi-mi:krup_drome(display_long)|uniprotkb:Kr(gene name)|psi-mi:Kr(display_short)|uniprotkb:CG3340(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873442 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523867.1|flybase:FBgn0001325|refseq:NP_001261181.1|ensemblmetazoa:FBgn0001325(gene)|ensemblmetazoa:FBtr0072449(transcript)|ensemblmetazoa:FBtr0333162(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007517"(muscle organ development)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061332"(Malpighian tubule bud morphogenesis)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR031243|interpro:IPR036236 refseq:NP_523867.1|flybase:FBgn0001325|refseq:NP_001261181.1|ensemblmetazoa:FBgn0001325(gene)|ensemblmetazoa:FBtr0072449(transcript)|ensemblmetazoa:FBtr0333162(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007517"(muscle organ development)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035290"(trunk segmentation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048749"(compound eye development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061332"(Malpighian tubule bud morphogenesis)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR031243|interpro:IPR036236 pubmed:8332216(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:r0X90GV+LseJkjX0mKqmA6xjcns7227 rogid:r0X90GV+LseJkjX0mKqmA6xjcns7227 intact-crc:1AEB82E61A810B3A|rigid:HZKoNLDJB6w+sMHYWpkVrJG3phQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q86P37 uniprotkb:Q9VVJ6 intact:EBI-870063|ensemblmetazoa:FBpp0072596 intact:EBI-174483|ensemblmetazoa:FBpp0074961 psi-mi:q86p37_drome(display_long)|uniprotkb:stet(gene name)|psi-mi:stet(display_short)|uniprotkb:rho-2(gene name synonym)|uniprotkb:CG33166(orf name) psi-mi:q9vvj6_drome(display_long)|uniprotkb:Krn(gene name)|psi-mi:Krn(display_short)|uniprotkb:Keren(gene name synonym)|uniprotkb:CT19073(gene name synonym)|uniprotkb:Dmel\CG32179(gene name synonym)|uniprotkb:Ker(gene name synonym)|uniprotkb:gritz(gene name synonym)|uniprotkb:keren(gene name synonym)|uniprotkb:krn(gene name synonym)|uniprotkb:s-krn(gene name synonym)|uniprotkb:skrn(gene name synonym)|uniprotkb:spitz2(gene name synonym)|uniprotkb:Dmel_CG32179(orf name)|uniprotkb:CG8056(gene name synonym)|uniprotkb:CG32179(orf name)|uniprotkb:KRN(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873446 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0020248|ensemblmetazoa:FBgn0020248(gene)|ensemblmetazoa:FBtr0072712(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR017213(Peptidase S54, rhomboid, metazoan)|interpro:IPR022764|interpro:IPR035952 refseq:NP_524129.1|flybase:FBgn0052179|go:"GO:0016021"(integral component of membrane)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048749"(compound eye development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|ensemblmetazoa:FBgn0052179(gene)|ensemblmetazoa:FBtr0075197(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning) pubmed:12169630(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:/V81SvMh6SpQatDYm99oUPvZ9887227 rogid:F2CAuU2khjCjOygFAuFiVYiNcbk7227 intact-crc:6793EB17AECAC200|rigid:Q1TQE3kaj1w9FGy45sHLjW5AMzY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42519 uniprotkb:Q9VVJ6 intact:EBI-184916|uniprotkb:Q9VPW0|ensemblmetazoa:FBpp0077658|ensemblmetazoa:FBpp0077659 intact:EBI-174483|ensemblmetazoa:FBpp0074961 psi-mi:star_drome(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:CG4385(orf name) psi-mi:q9vvj6_drome(display_long)|uniprotkb:Krn(gene name)|psi-mi:Krn(display_short)|uniprotkb:Keren(gene name synonym)|uniprotkb:CT19073(gene name synonym)|uniprotkb:Dmel\CG32179(gene name synonym)|uniprotkb:Ker(gene name synonym)|uniprotkb:gritz(gene name synonym)|uniprotkb:keren(gene name synonym)|uniprotkb:krn(gene name synonym)|uniprotkb:s-krn(gene name synonym)|uniprotkb:skrn(gene name synonym)|uniprotkb:spitz2(gene name synonym)|uniprotkb:Dmel_CG32179(orf name)|uniprotkb:CG8056(gene name synonym)|uniprotkb:CG32179(orf name)|uniprotkb:KRN(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873450 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523450.1|refseq:NP_722674.1|flybase:FBgn0003310|dip:DIP-22174N|ensemblmetazoa:FBgn0003310(gene)|ensemblmetazoa:FBtr0077993(transcript)|ensemblmetazoa:FBtr0077994(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007421"(stomatogastric nervous system development)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007601"(visual perception)|go:"GO:0016197"(endosomal transport)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|mint:P42519 refseq:NP_524129.1|flybase:FBgn0052179|go:"GO:0016021"(integral component of membrane)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048749"(compound eye development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|ensemblmetazoa:FBgn0052179(gene)|ensemblmetazoa:FBtr0075197(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning) pubmed:12169630(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8RiR9AUQmUsZN2w2weQ74nTjbls7227 rogid:F2CAuU2khjCjOygFAuFiVYiNcbk7227 intact-crc:F005F28942F068B3|rigid:Q8Krg8ZwYpA+0x3bd9Lkxq9lUMo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9W0F8 uniprotkb:Q9VVJ6 intact:EBI-159101|ensemblmetazoa:FBpp0072574|uniprotkb:Q9BML3 intact:EBI-174483|ensemblmetazoa:FBpp0074961 psi-mi:q9w0f8_drome(display_long)|uniprotkb:ru(gene name)|psi-mi:ru(display_short)|uniprotkb:Dmel\CG1214(gene name synonym)|uniprotkb:Rho-3(gene name synonym)|uniprotkb:Rho-related [62A1](gene name synonym)|uniprotkb:Rho3(gene name synonym)|uniprotkb:rho-3(gene name synonym)|uniprotkb:rho3(gene name synonym)|uniprotkb:Dmel_CG1214(orf name)|uniprotkb:CG1214(orf name) psi-mi:q9vvj6_drome(display_long)|uniprotkb:Krn(gene name)|psi-mi:Krn(display_short)|uniprotkb:Keren(gene name synonym)|uniprotkb:CT19073(gene name synonym)|uniprotkb:Dmel\CG32179(gene name synonym)|uniprotkb:Ker(gene name synonym)|uniprotkb:gritz(gene name synonym)|uniprotkb:keren(gene name synonym)|uniprotkb:krn(gene name synonym)|uniprotkb:s-krn(gene name synonym)|uniprotkb:skrn(gene name synonym)|uniprotkb:spitz2(gene name synonym)|uniprotkb:Dmel_CG32179(orf name)|uniprotkb:CG8056(gene name synonym)|uniprotkb:CG32179(orf name)|uniprotkb:KRN(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873454 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0003295(gene)|ensemblmetazoa:FBtr0072681(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001752"(compound eye photoreceptor fate commitment)|go:"GO:0003015"(heart process)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|go:"GO:0042676"(compound eye cone cell fate commitment)|go:"GO:0045177"(apical part of cell)|go:"GO:0050714"(positive regulation of protein secretion)|interpro:IPR017213(Peptidase S54, rhomboid, metazoan)|interpro:IPR022764|interpro:IPR035952|refseq:NP_524790.1|flybase:FBgn0003295 refseq:NP_524129.1|flybase:FBgn0052179|go:"GO:0016021"(integral component of membrane)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048749"(compound eye development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|ensemblmetazoa:FBgn0052179(gene)|ensemblmetazoa:FBtr0075197(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning) pubmed:12169630(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Fl5art/krhlG8AxqX+r9kU7Iy1o7227 rogid:F2CAuU2khjCjOygFAuFiVYiNcbk7227 intact-crc:D6347A64D1FE84C4|rigid:dzIy5nJW55ijVcSBk6YZuFL9nAw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VYW6 uniprotkb:Q9VVJ6 intact:EBI-108271|ensemblmetazoa:FBpp0073365|ensemblmetazoa:FBpp0073366 intact:EBI-174483|ensemblmetazoa:FBpp0074961 psi-mi:q9vyw6_drome(display_long)|uniprotkb:rho-4(gene name)|psi-mi:rho-4(display_short)|uniprotkb:DmRho4(gene name synonym)|uniprotkb:Dmel\CG1697(gene name synonym)|uniprotkb:Rho-4(gene name synonym)|uniprotkb:Rho-related [10C6](gene name synonym)|uniprotkb:rho 4(gene name synonym)|uniprotkb:rho4(gene name synonym)|uniprotkb:Dmel_CG1697(orf name)|uniprotkb:CG1697(orf name) psi-mi:q9vvj6_drome(display_long)|uniprotkb:Krn(gene name)|psi-mi:Krn(display_short)|uniprotkb:Keren(gene name synonym)|uniprotkb:CT19073(gene name synonym)|uniprotkb:Dmel\CG32179(gene name synonym)|uniprotkb:Ker(gene name synonym)|uniprotkb:gritz(gene name synonym)|uniprotkb:keren(gene name synonym)|uniprotkb:krn(gene name synonym)|uniprotkb:s-krn(gene name synonym)|uniprotkb:skrn(gene name synonym)|uniprotkb:spitz2(gene name synonym)|uniprotkb:Dmel_CG32179(orf name)|uniprotkb:CG8056(gene name synonym)|uniprotkb:CG32179(orf name)|uniprotkb:KRN(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873458 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_727538.1|flybase:FBgn0030318|refseq:NP_525084.1|ensemblmetazoa:FBgn0030318(gene)|ensemblmetazoa:FBtr0073518(transcript)|ensemblmetazoa:FBtr0073519(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR017213(Peptidase S54, rhomboid, metazoan)|interpro:IPR018247|interpro:IPR022764|interpro:IPR035952 refseq:NP_524129.1|flybase:FBgn0052179|go:"GO:0016021"(integral component of membrane)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048749"(compound eye development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|ensemblmetazoa:FBgn0052179(gene)|ensemblmetazoa:FBtr0075197(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning) pubmed:12169630(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:rNG5P1Q+0DjT0WpIkQVw1obOprk7227 rogid:F2CAuU2khjCjOygFAuFiVYiNcbk7227 intact-crc:4C754EF941FE77B4|rigid:cSvfq+2YDKqVJIx2pXwuSc3VGhE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20350 uniprotkb:Q9VVJ6 intact:EBI-172815|uniprotkb:Q9W0F2|ensemblmetazoa:FBpp0072578|ensemblmetazoa:FBpp0305409 intact:EBI-174483|ensemblmetazoa:FBpp0074961 psi-mi:rhom_drome(display_long)|uniprotkb:rho(gene name)|psi-mi:rho(display_short)|uniprotkb:Ve(gene name synonym)|uniprotkb:CG1004(orf name)|uniprotkb:Protein veinlet(gene name synonym) psi-mi:q9vvj6_drome(display_long)|uniprotkb:Krn(gene name)|psi-mi:Krn(display_short)|uniprotkb:Keren(gene name synonym)|uniprotkb:CT19073(gene name synonym)|uniprotkb:Dmel\CG32179(gene name synonym)|uniprotkb:Ker(gene name synonym)|uniprotkb:gritz(gene name synonym)|uniprotkb:keren(gene name synonym)|uniprotkb:krn(gene name synonym)|uniprotkb:s-krn(gene name synonym)|uniprotkb:skrn(gene name synonym)|uniprotkb:spitz2(gene name synonym)|uniprotkb:Dmel_CG32179(orf name)|uniprotkb:CG8056(gene name synonym)|uniprotkb:CG32179(orf name)|uniprotkb:KRN(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873462 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523883.2|flybase:FBgn0004635|refseq:NP_001261255.1|go:"GO:0001752"(compound eye photoreceptor fate commitment)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007436"(larval salivary gland morphogenesis)|go:"GO:0007438"(oenocyte development)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|ensemblmetazoa:FBgn0004635(gene)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035311"(wing cell fate specification)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045177"(apical part of cell)|ensemblmetazoa:FBtr0072694(transcript)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0090317"(negative regulation of intracellular protein transport)|interpro:IPR017213(Peptidase S54, rhomboid, metazoan)|interpro:IPR022764|ensemblmetazoa:FBtr0333207(transcript)|interpro:IPR035952|go:"GO:0000281"(mitotic cytokinesis)|mint:P20350|go:"GO:0001742"(oenocyte differentiation) refseq:NP_524129.1|flybase:FBgn0052179|go:"GO:0016021"(integral component of membrane)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048749"(compound eye development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|ensemblmetazoa:FBgn0052179(gene)|ensemblmetazoa:FBtr0075197(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning) pubmed:12169630(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:1xLHqeP8taUKQZy9DJw9AkfcVr07227 rogid:F2CAuU2khjCjOygFAuFiVYiNcbk7227 intact-crc:5F660FBBB3258911|rigid:WHcLLd4H/egJvv0Rxaqi+mdTy78 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P11346 uniprotkb:Q24170 intact:EBI-664624|uniprotkb:Q9W4Z3|uniprotkb:Q8I086|uniprotkb:Q8I0D9|uniprotkb:Q8ISE1|uniprotkb:Q8ISE2|uniprotkb:Q8ISE3|uniprotkb:Q9NEH9|uniprotkb:A8JUV5|uniprotkb:Q0KHW7|ensemblmetazoa:FBpp0070385|ensemblmetazoa:FBpp0310458 intact:EBI-868769 psi-mi:kraf1_drome(display_long)|uniprotkb:Raf(gene name)|psi-mi:Raf(display_short)|uniprotkb:Protein pole-hole(gene name synonym)|uniprotkb:ph(gene name synonym)|uniprotkb:phl(gene name synonym)|uniprotkb:CG2845(orf name) psi-mi:q24170_drome(display_long)|uniprotkb:ksr(gene name)|psi-mi:ksr(display_short)|uniprotkb:CG2899(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873466 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525047.1|flybase:FBgn0003079|refseq:NP_001096867.3|dip:DIP-29769N|ensemblmetazoa:FBgn0003079(gene)|ensemblmetazoa:FBtr0070401(transcript)|ensemblmetazoa:FBtr0344007(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0002168"(instar larval development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007552"(metamorphosis)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042386"(hemocyte differentiation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029071|reactome:R-DME-1295596|reactome:R-DME-170968|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-432553|reactome:R-DME-5621575|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5675482 flybase:FBgn0015402|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR025561|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-432553 pubmed:11850406(see-also)|pubmed:11741918(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:rbvsd7+5RvYrFoXyonEM6Li84hM7227 rogid:ZsbLCPNIB7ojheTNUv7Htgd7Yrg7227 intact-crc:B40F0F4D059A7800|rigid:WYXcJfPsvt7mjmAPiEo0iqkZz/4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07207 uniprotkb:Q94902 intact:EBI-103438|uniprotkb:O97458|uniprotkb:P04154|uniprotkb:Q9W4T8|ensemblmetazoa:FBpp0070483|ensemblmetazoa:FBpp0293201 intact:EBI-869108 psi-mi:notch_drome(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:CG3936(orf name) psi-mi:q94902_drome(display_long)|uniprotkb:kuz(gene name)|psi-mi:kuz(display_short)|uniprotkb:CG7147(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873470 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476859.2|flybase:FBgn0004647|ensemblmetazoa:FBgn0004647(gene)|ensemblmetazoa:FBtr0070507(transcript)|ensemblmetazoa:FBtr0304659(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002213"(defense response to insect)|go:"GO:0003682"(chromatin binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007391"(dorsal closure)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009608"(response to symbiont)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0022416"(chaeta development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0007498"(mesoderm development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0007616"(long-term memory)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0040008"(regulation of growth)|go:"GO:0042686"(regulation of cardioblast cell fate specification)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045316"(negative regulation of compound eye photoreceptor development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048627"(myoblast development)|go:"GO:0048664"(neuron fate determination)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050699"(WW domain binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0060289"(compartment boundary maintenance)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990433"(CSL-Notch-Mastermind transcription factor complex)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1OT8|rcsb pdb:2JMF|refseq:NP_001245510.1|dip:DIP-5N flybase:FBgn0259984|go:"GO:0003007"(heart morphogenesis)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0008347"(glial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0035051"(cardiocyte differentiation)|go:"GO:0035386"(regulation of Roundabout signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0098595"(perivitelline space)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR024079|interpro:IPR034025|interpro:IPR036436 pubmed:11799064(see-also)|pubmed:9244301(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:T1iHJGMHXkhxbFRybmSDlizN7oQ7227 rogid:grwh/VZudq+kFSrdfeWejjN5xlo7227 intact-crc:CCB3E2DA18362A88|rigid:YebijG4uDcCe0Eok4NYEOFyExdc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10084 uniprotkb:P09774 intact:EBI-174136|intact:EBI-1639078|uniprotkb:O76890|uniprotkb:Q4V705|ensemblmetazoa:FBpp0070072 intact:EBI-174224|intact:EBI-1628024|uniprotkb:Q24387|uniprotkb:Q8MRA5|ensemblmetazoa:FBpp0070073 psi-mi:ast4_drome(display_long)|uniprotkb:sc(gene name)|psi-mi:sc(display_short)|uniprotkb:T4(gene name synonym)|uniprotkb:Protein scute(gene name synonym)|uniprotkb:sis-b(gene name synonym)|uniprotkb:CG3827(orf name) psi-mi:ast3_drome(display_long)|uniprotkb:"l(1)sc"(gene name)|psi-mi:"l(1)sc"(display_short)|uniprotkb:T3(gene name synonym)|uniprotkb:l'sc(gene name synonym)|uniprotkb:CG3839(orf name)|uniprotkb:Protein lethal of scute(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873474 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476803.1|flybase:FBgn0004170|dip:DIP-325N|ensemblmetazoa:FBgn0004170(gene)|ensemblmetazoa:FBtr0070073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638 refseq:NP_476623.1|flybase:FBgn0002561|ensemblmetazoa:FBgn0002561(gene)|ensemblmetazoa:FBtr0070074(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638 pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:WTTmp3SuZ10YiZMKYALr68UiRO07227 rogid:6/qKHfmqMOsi8uWoKA4A3IbeOGk7227 intact-crc:938DC47E08B32ADF|rigid:Le5OhDkfphS3ozdXLsQthIf097c false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09774 uniprotkb:P09774 intact:EBI-174224|intact:EBI-1628024|uniprotkb:Q24387|uniprotkb:Q8MRA5|ensemblmetazoa:FBpp0070073 intact:EBI-174224|intact:EBI-1628024|uniprotkb:Q24387|uniprotkb:Q8MRA5|ensemblmetazoa:FBpp0070073 psi-mi:ast3_drome(display_long)|uniprotkb:"l(1)sc"(gene name)|psi-mi:"l(1)sc"(display_short)|uniprotkb:T3(gene name synonym)|uniprotkb:l'sc(gene name synonym)|uniprotkb:CG3839(orf name)|uniprotkb:Protein lethal of scute(gene name synonym) psi-mi:ast3_drome(display_long)|uniprotkb:"l(1)sc"(gene name)|psi-mi:"l(1)sc"(display_short)|uniprotkb:T3(gene name synonym)|uniprotkb:l'sc(gene name synonym)|uniprotkb:CG3839(orf name)|uniprotkb:Protein lethal of scute(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873478 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476623.1|flybase:FBgn0002561|ensemblmetazoa:FBgn0002561(gene)|ensemblmetazoa:FBtr0070074(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638 refseq:NP_476623.1|flybase:FBgn0002561|ensemblmetazoa:FBgn0002561(gene)|ensemblmetazoa:FBtr0070074(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638 pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6/qKHfmqMOsi8uWoKA4A3IbeOGk7227 rogid:6/qKHfmqMOsi8uWoKA4A3IbeOGk7227 intact-crc:1AED1C38D539B108|rigid:dkVwn4u8wLeDN3bjHgVW9rCRQo8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q99323 uniprotkb:P08111 intact:EBI-118064|uniprotkb:Q24138|uniprotkb:Q7JPC1|uniprotkb:Q7JPC2|uniprotkb:Q8MMC2|uniprotkb:Q94987|uniprotkb:Q94992|uniprotkb:Q9W0W8 intact:EBI-497569|uniprotkb:Q0E8V5|uniprotkb:Q24377|uniprotkb:D0IQ91|uniprotkb:D0IQJ0|uniprotkb:Q8IPV4|uniprotkb:Q8IPV5|uniprotkb:Q9VPI1|uniprotkb:A4UZW0|ensemblmetazoa:FBpp0077828|ensemblmetazoa:FBpp0077829|ensemblmetazoa:FBpp0297544|ensemblmetazoa:FBpp0297545|ensemblmetazoa:FBpp0297546|ensemblmetazoa:FBpp0297547 psi-mi:mysn_drome(display_long)|uniprotkb:zip(gene name)|psi-mi:zip(display_short)|uniprotkb:CG15792(orf name)|uniprotkb:Zipper protein(gene name synonym)|uniprotkb:Myosin II(gene name synonym)|uniprotkb:Non-muscle MHC(gene name synonym) psi-mi:l2gl_drome(display_long)|uniprotkb:"l(2)gl"(gene name)|psi-mi:"l(2)gl"(display_short)|uniprotkb:CG2671(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873482 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005938"(cell cortex)|go:"GO:0006936"(muscle contraction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007496"(anterior midgut development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008258"(head involution)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031036"(myosin II filament assembly)|go:"GO:0031252"(cell leading edge)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0005524"(ATP binding)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046663"(dorsal closure, leading edge cell differentiation)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0051015"(actin filament binding)|go:"GO:0060289"(compartment boundary maintenance)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|refseq:NP_523860.2|refseq:NP_726506.1|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|reactome:R-DME-350480|reactome:R-DME-5627123|flybase:FBgn0287873 refseq:NP_523439.2|refseq:NP_722583.1|refseq:NP_722584.1|refseq:NP_722585.1|refseq:NP_722586.1|refseq:NP_722587.1|flybase:FBgn0002121|refseq:NP_001245801.1|refseq:NP_001245802.1|refseq:NP_001245803.1|refseq:NP_001245804.1|dip:DIP-22687N|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005920"(smooth septate junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006887"(exocytosis)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007423"(sensory organ development)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016333"(morphogenesis of follicular epithelium)|go:"GO:0016334"(establishment or maintenance of polarity of follicular epithelium)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0017022"(myosin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019991"(septate junction assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031256"(leading edge membrane)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0035070"(salivary gland histolysis)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0045159"(myosin II binding)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045176"(apical protein localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045196"(establishment or maintenance of neuroblast polarity)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051668"(localization within membrane)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:0098725"(symmetric cell division)|go:"GO:1904580"(regulation of intracellular mRNA localization)|interpro:IPR000664("Lethal(2) giant larvae protein")|interpro:IPR013577(Lethal giant larvae homologue 2)|interpro:IPR013905("Lethal giant larvae (Lgl) like, C-terminal")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|ensemblmetazoa:FBgn0002121(gene)|ensemblmetazoa:FBtr0078170(transcript)|ensemblmetazoa:FBtr0078171(transcript)|ensemblmetazoa:FBtr0306589(transcript)|ensemblmetazoa:FBtr0306590(transcript)|ensemblmetazoa:FBtr0306591(transcript)|ensemblmetazoa:FBtr0306592(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0004860"(protein kinase inhibitor activity) pubmed:8799824(see-also)|pubmed:7962095(see-also) crc64:0D59519C1E83A411 - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:G6d6geCoR3HKWHNwB69h8p2n8cA7227 rogid:wMEqgAEqWRfMWlyvB1PjKBJ/vuI7227 intact-crc:EFB755F59CBFBAE5|rigid:bxS8uojDMhRK0xp/CJegdLnrP+E false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42003 uniprotkb:Q9V853 intact:EBI-162238|uniprotkb:Q9VQM3|ensemblmetazoa:FBpp0077302 intact:EBI-133520|uniprotkb:Q9U3W2|ensemblmetazoa:FBpp0086011|ensemblmetazoa:FBpp0305371 psi-mi:mad_drome(display_long)|uniprotkb:Mad(gene name)|psi-mi:Mad(display_short)|uniprotkb:CG12399(orf name) psi-mi:smuf1_drome(display_long)|uniprotkb:Smurf(gene name)|psi-mi:Smurf(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase Smurf1(gene name synonym)|uniprotkb:Lethal with a checkpoint kinase protein(gene name synonym)|uniprotkb:SMAD ubiquitination regulatory factor 1 homolog(gene name synonym)|uniprotkb:Smurf1(gene name synonym)|uniprotkb:lack(gene name synonym)|uniprotkb:CG4943(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873486 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477017.1|flybase:FBgn0011648|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007419"(ventral cord development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007560"(imaginal disc morphogenesis)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0009653"(anatomical structure morphogenesis)|ensemblmetazoa:FBgn0011648(gene)|ensemblmetazoa:FBtr0077616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035290"(trunk segmentation)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060799"(transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|rcsb pdb:3DIT|reactome:R-DME-201451|reactome:R-DME-8941326|rcsb pdb:3GMJ|dip:DIP-18256N refseq:NP_523779.1|flybase:FBgn0029006|refseq:NP_001261061.1|ensemblmetazoa:FBgn0029006(gene)|ensemblmetazoa:FBtr0086833(transcript)|ensemblmetazoa:FBtr0333168(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0040008"(regulation of growth)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048232"(male gamete generation)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035983|interpro:IPR036020|reactome:R-DME-201451|reactome:R-DME-2173788|reactome:R-DME-2173791|reactome:R-DME-2173795|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-5632684|reactome:R-DME-8941858|reactome:R-DME-983168|interpro:IPR035892 pubmed:11703946(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:WIV5vzeVJTr8sKiZNxHA9qmPahE7227 rogid:y+MepmRUDbeDXaSYafJ8vxu5W4U7227 intact-crc:5944E99CC9178773|rigid:k6gYtygMmRJtGmeKb1mc6ix+7mU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20240 uniprotkb:P08928 intact:EBI-115143|uniprotkb:Q9V8E5|ensemblmetazoa:FBpp0085947 intact:EBI-188444|uniprotkb:Q9VMQ0|ensemblmetazoa:FBpp0078733|ensemblmetazoa:FBpp0297901|ensemblmetazoa:FBpp0297902|ensemblmetazoa:FBpp0312110 psi-mi:ote_drome(display_long)|uniprotkb:Ote(gene name)|psi-mi:Ote(display_short)|uniprotkb:LEM domain-containing protein Otefin(gene name synonym)|uniprotkb:CG5581(orf name) psi-mi:lam0_drome(display_long)|uniprotkb:Lam(gene name)|psi-mi:Lam(display_short)|uniprotkb:CG6944(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873490 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0266420(gene)|ensemblmetazoa:FBtr0086768(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048477"(oogenesis)|go:"GO:0051301"(cell division)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|flybase:FBgn0266420|refseq:NP_476664.2 refseq:NP_476616.1|flybase:FBgn0002525|refseq:NP_001245892.1|refseq:NP_001245893.1|refseq:NP_001285629.1|dip:DIP-2663N|ensemblmetazoa:FBgn0002525(gene)|ensemblmetazoa:FBtr0079100(transcript)|ensemblmetazoa:FBtr0307058(transcript)|ensemblmetazoa:FBtr0307059(transcript)|ensemblmetazoa:FBtr0346460(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007097"(nuclear migration)|go:"GO:0007110"(meiosis I cytokinesis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007569"(cell aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0048137"(spermatocyte division)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:2000433"(positive regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-DME-352238|reactome:R-DME-4419969|reactome:R-DME-9013405|reactome:R-DME-9035034 pubmed:9632815(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:aKtK7UUuUQFU0zncT/4tjZEpE5k7227 rogid:Kuv16J8T6uZ7lIJaqjVrdn9x5WU7227 intact-crc:FB633A961860BC09|rigid:dejps802FcATXuDa1JrhpT+WlcY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08928 uniprotkb:P08928 intact:EBI-188444|uniprotkb:Q9VMQ0|ensemblmetazoa:FBpp0078733|ensemblmetazoa:FBpp0297901|ensemblmetazoa:FBpp0297902|ensemblmetazoa:FBpp0312110 intact:EBI-188444|uniprotkb:Q9VMQ0|ensemblmetazoa:FBpp0078733|ensemblmetazoa:FBpp0297901|ensemblmetazoa:FBpp0297902|ensemblmetazoa:FBpp0312110 psi-mi:lam0_drome(display_long)|uniprotkb:Lam(gene name)|psi-mi:Lam(display_short)|uniprotkb:CG6944(orf name) psi-mi:lam0_drome(display_long)|uniprotkb:Lam(gene name)|psi-mi:Lam(display_short)|uniprotkb:CG6944(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873494 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476616.1|flybase:FBgn0002525|refseq:NP_001245892.1|refseq:NP_001245893.1|refseq:NP_001285629.1|dip:DIP-2663N|ensemblmetazoa:FBgn0002525(gene)|ensemblmetazoa:FBtr0079100(transcript)|ensemblmetazoa:FBtr0307058(transcript)|ensemblmetazoa:FBtr0307059(transcript)|ensemblmetazoa:FBtr0346460(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007097"(nuclear migration)|go:"GO:0007110"(meiosis I cytokinesis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007569"(cell aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0048137"(spermatocyte division)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:2000433"(positive regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-DME-352238|reactome:R-DME-4419969|reactome:R-DME-9013405|reactome:R-DME-9035034 refseq:NP_476616.1|flybase:FBgn0002525|refseq:NP_001245892.1|refseq:NP_001245893.1|refseq:NP_001285629.1|dip:DIP-2663N|ensemblmetazoa:FBgn0002525(gene)|ensemblmetazoa:FBtr0079100(transcript)|ensemblmetazoa:FBtr0307058(transcript)|ensemblmetazoa:FBtr0307059(transcript)|ensemblmetazoa:FBtr0346460(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007097"(nuclear migration)|go:"GO:0007110"(meiosis I cytokinesis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007569"(cell aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0048137"(spermatocyte division)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:2000433"(positive regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-DME-352238|reactome:R-DME-4419969|reactome:R-DME-9013405|reactome:R-DME-9035034 pubmed:9774545(see-also)|pubmed:8776884(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Kuv16J8T6uZ7lIJaqjVrdn9x5WU7227 rogid:Kuv16J8T6uZ7lIJaqjVrdn9x5WU7227 intact-crc:822412A7C3976D17|rigid:Ujv2ORbksQGnBXogmMPaX8HJYOU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24247 uniprotkb:Q00174 intact:EBI-187829|uniprotkb:M9PEG3|uniprotkb:M9PHG7|uniprotkb:M9PJL8|uniprotkb:Q8SY51|uniprotkb:Q9VYF6|ensemblmetazoa:FBpp0073563 intact:EBI-138476|uniprotkb:Q9VRW0|ensemblmetazoa:FBpp0076722 psi-mi:ita1_drome(display_long)|uniprotkb:mew(gene name)|psi-mi:mew(display_short)|uniprotkb:CG1771(orf name)|uniprotkb:Position-specific antigen subunit alpha-1(gene name synonym)|uniprotkb:Protein multiple edematous wings(gene name synonym) psi-mi:lama_drome(display_long)|uniprotkb:LanA(gene name)|psi-mi:LanA(display_short)|uniprotkb:lamA(gene name synonym)|uniprotkb:CG10236(orf name)|uniprotkb:Laminin A chain(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873498 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511145.2|refseq:NP_727679.1|flybase:FBgn0004456|refseq:NP_001259503.1|refseq:NP_001259504.1|refseq:NP_001259505.1|ensemblmetazoa:FBgn0004456(gene)|ensemblmetazoa:FBtr0073732(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007414"(axonal defasciculation)|go:"GO:0007431"(salivary gland development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007475"(apposition of dorsal and ventral imaginal disc-derived wing surfaces)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008305"(integrin complex)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048567"(ectodermal digestive tract morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|reactome:R-DME-216083|reactome:R-DME-3000157|reactome:R-DME-3000170|reactome:R-DME-446107 go:"GO:0045995"(regulation of embryonic development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071711"(basement membrane organization)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR009254(Laminin I)|interpro:IPR010307(Laminin II)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|reactome:R-DME-1474228|reactome:R-DME-3000157|reactome:R-DME-446107|ensemblmetazoa:FBgn0002526(gene)|ensemblmetazoa:FBtr0077014(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035001"(dorsal trunk growth, open tracheal system)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|refseq:NP_476617.1|flybase:FBgn0002526 pubmed:9527881(see-also)|pubmed:7972082(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:lx6guHMeMxK+GXSLntQoBMuhuko7227 rogid:JFxJ12XAhFQZnPvENV7L4a7i19s7227 intact-crc:B25B145C54D11D6D|rigid:Jm1Nns8V5SpDt79UFxAcAAZYJ7c false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P15215 uniprotkb:P11046 intact:EBI-150670|uniprotkb:Q5BI30|uniprotkb:Q24373|uniprotkb:Q9VT18|ensemblmetazoa:FBpp0076111|ensemblmetazoa:FBpp0311281 intact:EBI-176205|uniprotkb:A4V0D8|uniprotkb:Q6AWM6|uniprotkb:Q8SWY0|uniprotkb:Q26328|uniprotkb:Q9VLW6|uniprotkb:Q9XZT4|ensemblmetazoa:FBpp0079113|ensemblmetazoa:FBpp0079114 psi-mi:lamc1_drome(display_long)|uniprotkb:LanB2(gene name)|psi-mi:LanB2(display_short)|uniprotkb:LAMC1(gene name synonym)|uniprotkb:LAMG1(gene name synonym)|uniprotkb:CG3322(orf name)|uniprotkb:Laminin B2 chain(gene name synonym) psi-mi:lamb1_drome(display_long)|uniprotkb:LanB1(gene name)|psi-mi:LanB1(display_short)|uniprotkb:lamB1(gene name synonym)|uniprotkb:CG7123(orf name)|uniprotkb:Laminin B1 chain(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873502 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0267348|refseq:NP_001287009.1|refseq:NP_524006.1|dip:DIP-21994N|ensemblmetazoa:FBgn0267348(gene)|ensemblmetazoa:FBtr0076382(transcript)|ensemblmetazoa:FBtr0345031(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0061031"(endodermal digestive tract morphogenesis)|go:"GO:0070831"(basement membrane assembly)|go:"GO:0071711"(basement membrane organization)|go:"GO:0085029"(extracellular matrix assembly)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|reactome:R-DME-1474228|reactome:R-DME-3000157|reactome:R-DME-381426|reactome:R-DME-446107|reactome:R-DME-8957275 refseq:NP_476618.1|refseq:NP_723319.1|flybase:FBgn0261800|ensemblmetazoa:FBgn0261800(gene)|ensemblmetazoa:FBtr0079490(transcript)|ensemblmetazoa:FBtr0079491(transcript)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008406"(gonad development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043256"(laminin complex)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048513"(animal organ development)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070831"(basement membrane assembly)|go:"GO:0071711"(basement membrane organization)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|reactome:R-DME-1474228|reactome:R-DME-3000157|reactome:R-DME-373752|reactome:R-DME-381426|reactome:R-DME-446107|reactome:R-DME-8957275 pubmed:9257722(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:QqR5GfiC1zF9tLHnsjm9suDJWtU7227 rogid:TRSRMFsah1k5KuLNdTjDqK0pttY7227 intact-crc:80547CC14F26555F|rigid:2w7NkMr70gFv95OWBA7/AwkA48w false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24168 uniprotkb:Q3YNA4 intact:EBI-179453|intact:EBI-1631787|uniprotkb:Q9VFP4|ensemblmetazoa:FBpp0082329 intact:EBI-870075 psi-mi:orc2_drome(display_long)|uniprotkb:Orc2(gene name)|psi-mi:Orc2(display_short)|uniprotkb:CG3041(orf name) psi-mi:q3yna4_drome(display_long)|uniprotkb:Orc3(gene name)|psi-mi:Orc3(display_short)|uniprotkb:lat(gene name synonym)|uniprotkb:CG4088(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873510 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_731873.1|flybase:FBgn0015270|dip:DIP-23209N|ensemblmetazoa:FBgn0015270(gene)|ensemblmetazoa:FBtr0082866(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005723"(alpha-heterochromatin)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0030261"(chromosome condensation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 flybase:FBgn0005654|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0008355"(olfactory learning)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:1903688"(positive regulation of border follicle cell migration) pubmed:10402192(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:SaBA2xfoQcWtCiLhN6rD5O5yMhg7227 rogid:JBJ8+eyCM9ty+zfnFxlkNBABEzs7227 intact-crc:34AA635C89144D01|rigid:FxehFvS974wqN6CNChO2WcHj+V0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P24014 uniprotkb:Q5U176 intact:EBI-498463|uniprotkb:Q24526|uniprotkb:Q8MLB9|uniprotkb:Q9V7F8|uniprotkb:Q9V7F9|uniprotkb:Q9XYV4|uniprotkb:A8DYF5|uniprotkb:A8DYF6|ensemblmetazoa:FBpp0303575|ensemblmetazoa:FBpp0303577 intact:EBI-870080 psi-mi:slit_drome(display_long)|uniprotkb:sli(gene name)|psi-mi:sli(display_short)|uniprotkb:CG43758(orf name) psi-mi:q5u176_drome(display_long)|uniprotkb:robo2(gene name)|psi-mi:robo2(display_short)|uniprotkb:lea(gene name synonym)|uniprotkb:CG5481(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873514 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097333.1|refseq:NP_001097334.1|refseq:NP_476727.1|refseq:NP_476728.1|refseq:NP_476729.1|flybase:FBgn0264089|ensemblmetazoa:FBgn0264089(gene)|ensemblmetazoa:FBtr0330731(transcript)|ensemblmetazoa:FBtr0330733(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007502"(digestive tract mesoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008201"(heparin binding)|go:"GO:0008347"(glial cell migration)|go:"GO:0008406"(gonad development)|go:"GO:0009986"(cell surface)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050929"(induction of negative chemotaxis)|go:"GO:0071666"(Slit-Robo signaling complex)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR032675|rcsb pdb:1W8A|reactome:R-DME-376176|reactome:R-DME-428890 flybase:FBgn0002543|go:"GO:0001764"(neuron migration)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007419"(ventral cord development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0008406"(gonad development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030424"(axon)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0042685"(cardioblast cell fate specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048036"(central complex development)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179 pubmed:11163179(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:v/6IXr7nKdgRcNRzTGPvyzwpoKY7227 rogid:oDtOju8FywnG346eA41pG+lf24Y7227 intact-crc:1E83AAB9C5CE46E2|rigid:cRBXg6gi2ZakzIihipNMK/4ADrI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9V9W8 uniprotkb:Q961D9 intact:EBI-152653|ensemblmetazoa:FBpp0085167 intact:EBI-85519|uniprotkb:Q9V4D2|ensemblmetazoa:FBpp0088180 psi-mi:pygo_drome(display_long)|uniprotkb:pygo(gene name)|psi-mi:pygo(display_short)|uniprotkb:gam(gene name synonym)|uniprotkb:CG11518(orf name)|uniprotkb:Protein gammy legs(gene name synonym) psi-mi:bcl9_drome(display_long)|uniprotkb:lgs(gene name)|psi-mi:lgs(display_short)|uniprotkb:BCL9(gene name synonym)|uniprotkb:CG2041(orf name)|uniprotkb:Protein legless(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873518 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651872.1|flybase:FBgn0043900|ensemblmetazoa:FBgn0043900(gene)|ensemblmetazoa:FBtr0085806(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|rcsb pdb:3ZPV|reactome:R-DME-201722|reactome:R-DME-209407|reactome:R-DME-209421|dip:DIP-29989N refseq:NP_651922.1|flybase:FBgn0039907|ensemblmetazoa:FBgn0039907(gene)|ensemblmetazoa:FBtr0089111(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007491"(sternite morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0035223"(leg disc pattern formation)|rcsb pdb:3ZPV|reactome:R-DME-201722|reactome:R-DME-209407|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|reactome:R-DME-209421|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR024670|dip:DIP-33392N pubmed:15208637(see-also)|pubmed:14612447(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Vg/PibxqoE0VAobzkEW0yTD6hSg7227 rogid:W5+IVXO6J6D9E9N7P5R6tFQ7bpc7227 intact-crc:EA51A0165F344770|rigid:zKwVOwJ3kKfhlK+5NJWPXTD2Y4Q false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O61443 uniprotkb:O62602 intact:EBI-82330|ensemblmetazoa:FBpp0080111 intact:EBI-107946|ensemblmetazoa:FBpp0073551 psi-mi:mk38b_drome(display_long)|uniprotkb:p38b(gene name)|psi-mi:p38b(display_short)|uniprotkb:CG7393(orf name) psi-mi:o62602_drome(display_long)|uniprotkb:lic(gene name)|psi-mi:lic(display_short)|uniprotkb:MKK3(gene name synonym)|uniprotkb:p38MAPKK(gene name synonym)|uniprotkb:Dmel_CG12244(orf name)|uniprotkb:D-MKK3(gene name synonym)|uniprotkb:DMEK3(gene name synonym)|uniprotkb:DMKK3(gene name synonym)|uniprotkb:DmMKK3(gene name synonym)|uniprotkb:Dmel\CG12244(gene name synonym)|uniprotkb:MEK3(gene name synonym)|uniprotkb:Mek3(gene name synonym)|uniprotkb:Mkk3(gene name synonym)|uniprotkb:Mpk3(gene name synonym)|uniprotkb:dMKK3(gene name synonym)|uniprotkb:"l(1)G0252"(gene name synonym)|uniprotkb:p38(gene name synonym)|uniprotkb:CG12244(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873522 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477361.1|flybase:FBgn0024846|go:"GO:0001934"(positive regulation of protein phosphorylation)|ensemblmetazoa:FBgn0024846(gene)|ensemblmetazoa:FBtr0080534(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0009617"(response to bacterium)|go:"GO:0009651"(response to salt stress)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038001"(paracrine signaling)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042594"(response to starvation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048082"(regulation of adult chitin-containing cuticle pigmentation)|go:"GO:0050832"(defense response to fungus)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-168638|reactome:R-DME-171007|reactome:R-DME-198753|reactome:R-DME-2559580|reactome:R-DME-376172|reactome:R-DME-418592|reactome:R-DME-432142|reactome:R-DME-4420097|reactome:R-DME-450302|reactome:R-DME-450341|reactome:R-DME-525793|reactome:R-DME-5675221|reactome:R-DME-6798695|dip:DIP-22779N refseq:NP_477162.1|flybase:FBgn0261524|ensemblmetazoa:FBgn0261524(gene)|ensemblmetazoa:FBtr0073720(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002385"(mucosal immune response)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048082"(regulation of adult chitin-containing cuticle pigmentation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|reactome:R-DME-168638|reactome:R-DME-2559580|reactome:R-DME-450302|reactome:R-DME-6811555 pubmed:9584193(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:rkuVJJgL+rmuXx8eEMG3/tjP8tE7227 rogid:+beA7Y2bGsmbJt7030eZmI7UvSU7227 intact-crc:FB5A7C8915B5022D|rigid:2PCBigXTqDAIaKWF5i+fGV8H2Jw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O62618 uniprotkb:O62602 intact:EBI-125935|uniprotkb:A4V3C0|uniprotkb:O46216|uniprotkb:Q9TXB4|ensemblmetazoa:FBpp0083965|ensemblmetazoa:FBpp0083966|ensemblmetazoa:FBpp0289799 intact:EBI-107946|ensemblmetazoa:FBpp0073551 psi-mi:mk38a_drome(display_long)|uniprotkb:p38a(gene name)|psi-mi:p38a(display_short)|uniprotkb:MAP kinase 14A(gene name synonym)|uniprotkb:Mpk2(gene name synonym)|uniprotkb:p38 MAPK(gene name synonym)|uniprotkb:CG5475(orf name) psi-mi:o62602_drome(display_long)|uniprotkb:lic(gene name)|psi-mi:lic(display_short)|uniprotkb:MKK3(gene name synonym)|uniprotkb:p38MAPKK(gene name synonym)|uniprotkb:Dmel_CG12244(orf name)|uniprotkb:D-MKK3(gene name synonym)|uniprotkb:DMEK3(gene name synonym)|uniprotkb:DMKK3(gene name synonym)|uniprotkb:DmMKK3(gene name synonym)|uniprotkb:Dmel\CG12244(gene name synonym)|uniprotkb:MEK3(gene name synonym)|uniprotkb:Mek3(gene name synonym)|uniprotkb:Mkk3(gene name synonym)|uniprotkb:Mpk3(gene name synonym)|uniprotkb:dMKK3(gene name synonym)|uniprotkb:"l(1)G0252"(gene name synonym)|uniprotkb:p38(gene name synonym)|uniprotkb:CG12244(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873526 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163711.1|refseq:NP_477163.1|refseq:NP_732959.1|flybase:FBgn0015765|go:"GO:0009408"(response to heat)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038001"(paracrine signaling)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042594"(response to starvation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048082"(regulation of adult chitin-containing cuticle pigmentation)|go:"GO:0050832"(defense response to fungus)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900407"(regulation of cellular response to oxidative stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|go:"GO:0008348"(negative regulation of antimicrobial humoral response)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-168638|reactome:R-DME-171007|reactome:R-DME-198753|reactome:R-DME-2559580|reactome:R-DME-376172|reactome:R-DME-4420097|reactome:R-DME-450302|reactome:R-DME-450341|reactome:R-DME-525793|reactome:R-DME-5675221|ensemblmetazoa:FBgn0015765(gene)|ensemblmetazoa:FBtr0084580(transcript)|ensemblmetazoa:FBtr0084581(transcript)|ensemblmetazoa:FBtr0300572(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0002385"(mucosal immune response)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006955"(immune response)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008340"(determination of adult lifespan) refseq:NP_477162.1|flybase:FBgn0261524|ensemblmetazoa:FBgn0261524(gene)|ensemblmetazoa:FBtr0073720(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002385"(mucosal immune response)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048082"(regulation of adult chitin-containing cuticle pigmentation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|reactome:R-DME-168638|reactome:R-DME-2559580|reactome:R-DME-450302|reactome:R-DME-6811555 pubmed:9584193(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Tr3U/xc9CPWbvchlyQI2yHXv98I7227 rogid:+beA7Y2bGsmbJt7030eZmI7UvSU7227 intact-crc:CDD5A9B4FA8D5F62|rigid:hwMYyVNkWKC9cPjsTR24UQlkPrI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P45594 uniprotkb:Q8IR79 intact:EBI-110774|uniprotkb:Q9W1C4|uniprotkb:C6SV25|ensemblmetazoa:FBpp0072097 intact:EBI-149780|uniprotkb:Q8IR78|uniprotkb:Q9GV18|uniprotkb:Q9GV19|uniprotkb:Q9VYL6|ensemblmetazoa:FBpp0073493 psi-mi:cadf_drome(display_long)|uniprotkb:Protein twinstar(gene name synonym)|uniprotkb:Protein D61(gene name synonym)|uniprotkb:tsr(gene name)|psi-mi:tsr(display_short)|uniprotkb:Cadf(gene name synonym)|uniprotkb:CG4254(orf name) psi-mi:limk1_drome(display_long)|uniprotkb:LIMK1(gene name)|psi-mi:LIMK1(display_short)|uniprotkb:CG1848(orf name)|uniprotkb:LIMK(gene name synonym)|uniprotkb:dLIMK(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873530 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477034.1|flybase:FBgn0011726|dip:DIP-20149N|ensemblmetazoa:FBgn0011726(gene)|ensemblmetazoa:FBtr0072188(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007409"(axonogenesis)|go:"GO:0008585"(female gonad development)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016319"(mushroom body development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0048749"(compound eye development)|go:"GO:0048870"(cell motility)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051299"(centrosome separation)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|rcsb pdb:2MV2 flybase:FBgn0283712|refseq:NP_001162733.1|refseq:NP_511139.2|refseq:NP_727621.1|refseq:NP_727622.1|ensemblmetazoa:FBgn0283712(gene)|ensemblmetazoa:FBtr0073660(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007560"(imaginal disc morphogenesis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036034|reactome:R-DME-2029482|reactome:R-DME-399954|reactome:R-DME-5627123 pubmed:11027607(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:khdE8vWqs/u/7AeaXb5MlajmjjM7227 rogid:dy7CpYdvHSjxHRGiPU/kYpXdOjI7227 intact-crc:5A32D493E7AB1C93|rigid:VZ+sfGed2IwHCwvqo3lcWoJad2E false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O77430 uniprotkb:Q24311 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 intact:EBI-136038|uniprotkb:A4UZ78|ensemblmetazoa:FBpp0087921|ensemblmetazoa:FBpp0087922|ensemblmetazoa:FBpp0087923|ensemblmetazoa:FBpp0087924|uniprotkb:Q0E9G0|uniprotkb:Q9V312 psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:cul1_drome(display_long)|uniprotkb:Cul1(gene name)|psi-mi:Cul1(display_short)|uniprotkb:Lin-19 homolog protein(gene name synonym)|uniprotkb:cul-1(gene name synonym)|uniprotkb:lin19(gene name synonym)|uniprotkb:CG1877(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873534 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 refseq:NP_523655.1|refseq:NP_724621.1|refseq:NP_724622.1|refseq:NP_724623.1|flybase:FBgn0015509|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904801"(positive regulation of neuron remodeling)|ensemblmetazoa:FBgn0015509(gene)|ensemblmetazoa:FBtr0088845(transcript)|ensemblmetazoa:FBtr0088846(transcript)|ensemblmetazoa:FBtr0088847(transcript)|ensemblmetazoa:FBtr0088848(transcript)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q24311|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168|dip:DIP-19461N pubmed:11500045(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 rogid:uik6AV9MpfMBKBZoYZSxvCl5bTc7227 intact-crc:F1E20BAA9A3CF9CF|rigid:J1oPCXolY80EWCMtFo55Kg5Nc+Y false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9W5E1 uniprotkb:Q24311 intact:EBI-153139|uniprotkb:O77429|ensemblmetazoa:FBpp0070117|ensemblmetazoa:FBpp0310165 intact:EBI-136038|uniprotkb:A4UZ78|ensemblmetazoa:FBpp0087921|ensemblmetazoa:FBpp0087922|ensemblmetazoa:FBpp0087923|ensemblmetazoa:FBpp0087924|uniprotkb:Q0E9G0|uniprotkb:Q9V312 psi-mi:rbx1a_drome(display_long)|uniprotkb:Roc1a(gene name)|psi-mi:Roc1a(display_short)|uniprotkb:CG16982(orf name)|uniprotkb:Regulator of cullins 1a(gene name synonym)|uniprotkb:dRbx1(gene name synonym) psi-mi:cul1_drome(display_long)|uniprotkb:Cul1(gene name)|psi-mi:Cul1(display_short)|uniprotkb:Lin-19 homolog protein(gene name synonym)|uniprotkb:cul-1(gene name synonym)|uniprotkb:lin19(gene name synonym)|uniprotkb:CG1877(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873538 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138143.2|ensemblmetazoa:FBgn0025638(gene)|ensemblmetazoa:FBtr0070122(transcript)|ensemblmetazoa:FBtr0343564(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|refseq:NP_569852.1|flybase:FBgn0025638|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016032"(viral process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045116"(protein neddylation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-DME-110314|reactome:R-DME-1234176|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-4641258|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-5696400|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-6782210|reactome:R-DME-68949|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|reactome:R-DME-983168|refseq:NP_001284754.1|dip:DIP-60717N refseq:NP_523655.1|refseq:NP_724621.1|refseq:NP_724622.1|refseq:NP_724623.1|flybase:FBgn0015509|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904801"(positive regulation of neuron remodeling)|ensemblmetazoa:FBgn0015509(gene)|ensemblmetazoa:FBtr0088845(transcript)|ensemblmetazoa:FBtr0088846(transcript)|ensemblmetazoa:FBtr0088847(transcript)|ensemblmetazoa:FBtr0088848(transcript)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q24311|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168|dip:DIP-19461N pubmed:11500045(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:cdi4DGamYmT/5salxPwmZnusYVA7227 rogid:uik6AV9MpfMBKBZoYZSxvCl5bTc7227 intact-crc:D2F91CFBFEEC4573|rigid:PDf+p1vjvH7lhQ7nKXjHBw8eRgg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40417 uniprotkb:Q8T9L5 intact:EBI-867790|uniprotkb:A0A021WW06|uniprotkb:Q7PL59|uniprotkb:Q9W5M2|uniprotkb:A8Y4W1|uniprotkb:A8Y4W2|uniprotkb:Q9W5M3|ensemblmetazoa:FBpp0112423|ensemblmetazoa:FBpp0112425|ensemblmetazoa:FBpp0112426|ensemblmetazoa:FBpp0311493 intact:EBI-92892|uniprotkb:Q9VFS7|ensemblmetazoa:FBpp0082276|ensemblmetazoa:FBpp0082277|ensemblmetazoa:FBpp0082278|ensemblmetazoa:FBpp0082279|ensemblmetazoa:FBpp0082280|ensemblmetazoa:FBpp0082281|ensemblmetazoa:FBpp0082282|ensemblmetazoa:FBpp0082283|ensemblmetazoa:FBpp0290703 psi-mi:erka_drome(display_long)|uniprotkb:Extracellular-regulated kinase A(gene name synonym)|uniprotkb:Protein rolled(gene name synonym)|uniprotkb:rl(gene name)|psi-mi:rl(display_short)|uniprotkb:ERKa(gene name synonym)|uniprotkb:CG12559(orf name)|uniprotkb:MAPK(gene name synonym) psi-mi:q8t9l5_drome(display_long)|uniprotkb:DmLKB1(gene name synonym)|uniprotkb:Dmel\CG9374(gene name synonym)|uniprotkb:LKB1(gene name synonym)|uniprotkb:PAR-4(gene name synonym)|uniprotkb:PAR4(gene name synonym)|uniprotkb:PEUTZ JEGHERS KINASE(gene name synonym)|uniprotkb:STK11(gene name synonym)|uniprotkb:"anon-EST:Posey135"(gene name synonym)|uniprotkb:dLKB1(gene name synonym)|uniprotkb:dlkb1(gene name synonym)|uniprotkb:par-4(gene name synonym)|uniprotkb:Dmel_CG9374(orf name)|uniprotkb:CG9374(orf name)|uniprotkb:Lkb1(gene name)|psi-mi:Lkb1(display_short)|uniprotkb:lkb1(gene name synonym)|uniprotkb:Par4(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873542 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001015121.3|refseq:NP_001104348.2|refseq:NP_001287635.1|refseq:NP_001015122.1|refseq:NP_001015123.1|refseq:NP_001104349.1|flybase:FBgn0003256|dip:DIP-17266N|ensemblmetazoa:FBgn0003256(gene)|ensemblmetazoa:FBtr0113700(transcript)|ensemblmetazoa:FBtr0113702(transcript)|ensemblmetazoa:FBtr0113703(transcript)|ensemblmetazoa:FBtr0345337(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007362"(terminal region determination)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000826"(regulation of heart morphogenesis)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P40417|reactome:R-DME-110056|reactome:R-DME-112409|reactome:R-DME-112411|reactome:R-DME-1295596|reactome:R-DME-162658|reactome:R-DME-170968|reactome:R-DME-198753|reactome:R-DME-202670|reactome:R-DME-2029482|reactome:R-DME-2559580|reactome:R-DME-2559582|reactome:R-DME-2559585|reactome:R-DME-2871796|reactome:R-DME-3371453|reactome:R-DME-375165|reactome:R-DME-437239|reactome:R-DME-445144|reactome:R-DME-450341|reactome:R-DME-456926|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5654733|reactome:R-DME-5663213|reactome:R-DME-5673001|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5687128|reactome:R-DME-6798695|reactome:R-DME-74749|reactome:R-DME-881907|reactome:R-DME-9634635|reactome:R-DME-9634638 refseq:NP_731844.1|refseq:NP_731845.1|refseq:NP_001163606.1|refseq:NP_650302.1|refseq:NP_731840.1|refseq:NP_731841.1|refseq:NP_731842.1|refseq:NP_731843.1|refseq:NP_731846.1|flybase:FBgn0038167|ensemblmetazoa:FBgn0038167(gene)|ensemblmetazoa:FBtr0082808(transcript)|ensemblmetazoa:FBtr0082809(transcript)|ensemblmetazoa:FBtr0082810(transcript)|ensemblmetazoa:FBtr0082811(transcript)|ensemblmetazoa:FBtr0082812(transcript)|ensemblmetazoa:FBtr0082813(transcript)|ensemblmetazoa:FBtr0082814(transcript)|ensemblmetazoa:FBtr0082815(transcript)|ensemblmetazoa:FBtr0301488(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007391"(dorsal closure)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030709"(border follicle cell delamination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045201"(maintenance of neuroblast polarity)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039154 pubmed:15487973(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:m7w7KhuZSyx3t+dR2TKtvx/vRtA7227 rogid:1GcU3qk9NZHUPp1Q9ykWZmvoEzM7227 intact-crc:851734ABEF4B3159|rigid:EPHVF9rFebTYjjehHYbYzzN5iT8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9NFR7 uniprotkb:O61267 intact:EBI-497189 intact:EBI-459145|ensemblmetazoa:FBpp0080860|uniprotkb:O61268|uniprotkb:P91876|uniprotkb:Q8SZS3 psi-mi:q9nfr7_drome(display_long)|uniprotkb:pins(gene name)|psi-mi:pins(display_short)|uniprotkb:raps(gene name synonym)|uniprotkb:CG5692(orf name) psi-mi:lok_drome(display_long)|uniprotkb:Protein loki(gene name synonym)|uniprotkb:dMNK(gene name synonym)|uniprotkb:lok(gene name)|psi-mi:lok(display_short)|uniprotkb:CG10895(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873546 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0040080|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0055059"(asymmetric neuroblast division)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-5693565|reactome:R-DME-6804756|reactome:R-DME-69473|reactome:R-DME-69541|reactome:R-DME-69601|reactome:R-DME-75035|ensemblmetazoa:FBgn0019686(gene)|ensemblmetazoa:FBtr0081328(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007281"(germ cell development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016607"(nuclear speck)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050321"(tau-protein kinase activity)|refseq:NP_477218.1|refseq:NP_477219.1|refseq:NP_724241.1|flybase:FBgn0019686 pubmed:12719437(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:bJLhIKptzMvBzyui3OKrX5Ey3sw7227 rogid:FZmIG1RfRlAOFh81NiMlZj1L/cg7227 intact-crc:88FEEE7DE63D8E82|rigid:VvJN62GPMX2H0+Yb5cpGVLHUZSY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O97102 uniprotkb:Q7KNM2 intact:EBI-114439|ensemblmetazoa:FBpp0078984|ensemblmetazoa:FBpp0312327 intact:EBI-74966|intact:EBI-1627711|ensemblmetazoa:FBpp0077741|ensemblmetazoa:FBpp0077742|ensemblmetazoa:FBpp0301731|ensemblmetazoa:FBpp0301732 psi-mi:o97102_drome(display_long)|uniprotkb:smt3(gene name)|psi-mi:smt3(display_short)|uniprotkb:Smt3(gene name synonym)|uniprotkb:DmSUMO-1(gene name synonym)|uniprotkb:Dm0342(gene name synonym)|uniprotkb:DmSmt3(gene name synonym)|uniprotkb:Dmel\CG4494(gene name synonym)|uniprotkb:Dmsmt3(gene name synonym)|uniprotkb:SMT3(gene name synonym)|uniprotkb:SUMO(gene name synonym)|uniprotkb:Sumo(gene name synonym)|uniprotkb:"anon-EST:Posey240"(gene name synonym)|uniprotkb:dSmt3(gene name synonym)|uniprotkb:dsmt3(gene name synonym)|uniprotkb:"l(2)04493"(gene name synonym)|uniprotkb:"l(2)SH0182"(gene name synonym)|uniprotkb:"l(2)SH2 0182"(gene name synonym)|uniprotkb:CG4494(orf name)|uniprotkb:sumo(gene name synonym)|uniprotkb:Dmel_CG4494(orf name) psi-mi:q7knm2_drome(display_long)|uniprotkb:lwr(gene name)|psi-mi:lwr(display_short)|uniprotkb:semi(gene name synonym)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:DUbc9(gene name synonym)|uniprotkb:DmUbc9(gene name synonym)|uniprotkb:Dmel\CG3018(gene name synonym)|uniprotkb:Dmubc9(gene name synonym)|uniprotkb:FBgn0010602(gene name synonym)|uniprotkb:Iwr(gene name synonym)|uniprotkb:Lwr(gene name synonym)|uniprotkb:Ubc 9(gene name synonym)|uniprotkb:Ubc-9(gene name synonym)|uniprotkb:UbcD9(gene name synonym)|uniprotkb:dUBC9(gene name synonym)|uniprotkb:dUbc9(gene name synonym)|uniprotkb:dip4(gene name synonym)|uniprotkb:hbl(gene name synonym)|uniprotkb:i105(gene name synonym)|uniprotkb:i56(gene name synonym)|uniprotkb:"l(2)01519"(gene name synonym)|uniprotkb:"l(2)02858"(gene name synonym)|uniprotkb:"l(2)05486"(gene name synonym)|uniprotkb:"l(2)05487"(gene name synonym)|uniprotkb:ubc9(gene name synonym)|uniprotkb:Dmel_CG3018(orf name)|uniprotkb:UBC9(gene name synonym)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:CG3018(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873554 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477411.1|go:"GO:0000940"(outer kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|ensemblmetazoa:FBgn0264922(gene)|ensemblmetazoa:FBtr0079356(transcript)|ensemblmetazoa:FBtr0346716(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016925"(protein sumoylation)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030496"(midbody)|go:"GO:0031386"(protein tag)|go:"GO:0035073"(pupariation)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:O97102|rcsb pdb:2K1F|reactome:R-DME-196791|reactome:R-DME-3065679|reactome:R-DME-3108214|reactome:R-DME-3232118|reactome:R-DME-3899300|reactome:R-DME-4090294|reactome:R-DME-4551638|reactome:R-DME-4570464|reactome:R-DME-4615885|reactome:R-DME-4755510|reactome:R-DME-5696395|refseq:NP_001303312.1|flybase:FBgn0264922 refseq:NP_476978.1|refseq:NP_722637.1|flybase:FBgn0010602|refseq:NP_001259833.1|refseq:NP_001259834.1|ensemblmetazoa:FBgn0010602(gene)|ensemblmetazoa:FBtr0078081(transcript)|ensemblmetazoa:FBtr0078082(transcript)|ensemblmetazoa:FBtr0310028(transcript)|ensemblmetazoa:FBtr0310029(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000940"(outer kinetochore)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007391"(dorsal closure)|go:"GO:0008354"(germ cell migration)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030721"(spectrosome organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033134"(ubiquitin activating enzyme binding)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0035207"(negative regulation of hemocyte proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0140540"(negative regulation melanotic encapsulation of foreign target)|go:"GO:1904677"(positive regulation of somatic stem cell division)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-196791|reactome:R-DME-3108214|reactome:R-DME-3232118|reactome:R-DME-3899300|reactome:R-DME-4090294|reactome:R-DME-4551638|reactome:R-DME-4570464|reactome:R-DME-4615885|reactome:R-DME-4755510|reactome:R-DME-5696395 pubmed:10629064(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:fqo3Y86DDI0SsWGEfanaOs8qJlk7227 rogid:0klFCJX3ACVlfPFXyh4vl9degjM7227 intact-crc:AF945B4F855C0D2D|rigid:6/XhKmZd3GMSgwlBGdCFvobSCo0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42207 uniprotkb:Q7KNM2 intact:EBI-120528|uniprotkb:Q9VRH5|uniprotkb:Q8IQ47|ensemblmetazoa:FBpp0076897 intact:EBI-74966|intact:EBI-1627711|ensemblmetazoa:FBpp0077741|ensemblmetazoa:FBpp0077742|ensemblmetazoa:FBpp0301731|ensemblmetazoa:FBpp0301732 psi-mi:sept1_drome(display_long)|uniprotkb:DIFF6 protein homolog(gene name synonym)|uniprotkb:Protein innocent bystander(gene name synonym)|uniprotkb:CG1403(orf name)|uniprotkb:Sep1(gene name)|psi-mi:Sep1(display_short)|uniprotkb:Diff6(gene name synonym)|uniprotkb:iby(gene name synonym) psi-mi:q7knm2_drome(display_long)|uniprotkb:lwr(gene name)|psi-mi:lwr(display_short)|uniprotkb:semi(gene name synonym)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:DUbc9(gene name synonym)|uniprotkb:DmUbc9(gene name synonym)|uniprotkb:Dmel\CG3018(gene name synonym)|uniprotkb:Dmubc9(gene name synonym)|uniprotkb:FBgn0010602(gene name synonym)|uniprotkb:Iwr(gene name synonym)|uniprotkb:Lwr(gene name synonym)|uniprotkb:Ubc 9(gene name synonym)|uniprotkb:Ubc-9(gene name synonym)|uniprotkb:UbcD9(gene name synonym)|uniprotkb:dUBC9(gene name synonym)|uniprotkb:dUbc9(gene name synonym)|uniprotkb:dip4(gene name synonym)|uniprotkb:hbl(gene name synonym)|uniprotkb:i105(gene name synonym)|uniprotkb:i56(gene name synonym)|uniprotkb:"l(2)01519"(gene name synonym)|uniprotkb:"l(2)02858"(gene name synonym)|uniprotkb:"l(2)05486"(gene name synonym)|uniprotkb:"l(2)05487"(gene name synonym)|uniprotkb:ubc9(gene name synonym)|uniprotkb:Dmel_CG3018(orf name)|uniprotkb:UBC9(gene name synonym)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:CG3018(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873558 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0011710(gene)|ensemblmetazoa:FBtr0077198(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0007349"(cellularization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|refseq:NP_523430.1|flybase:FBgn0011710|dip:DIP-18454N refseq:NP_476978.1|refseq:NP_722637.1|flybase:FBgn0010602|refseq:NP_001259833.1|refseq:NP_001259834.1|ensemblmetazoa:FBgn0010602(gene)|ensemblmetazoa:FBtr0078081(transcript)|ensemblmetazoa:FBtr0078082(transcript)|ensemblmetazoa:FBtr0310028(transcript)|ensemblmetazoa:FBtr0310029(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000940"(outer kinetochore)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007391"(dorsal closure)|go:"GO:0008354"(germ cell migration)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030721"(spectrosome organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033134"(ubiquitin activating enzyme binding)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0035207"(negative regulation of hemocyte proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0140540"(negative regulation melanotic encapsulation of foreign target)|go:"GO:1904677"(positive regulation of somatic stem cell division)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-196791|reactome:R-DME-3108214|reactome:R-DME-3232118|reactome:R-DME-3899300|reactome:R-DME-4090294|reactome:R-DME-4551638|reactome:R-DME-4570464|reactome:R-DME-4615885|reactome:R-DME-4755510|reactome:R-DME-5696395 pubmed:11884525(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:owbyZvFu8+uF3t60BTm9IqquTL47227 rogid:0klFCJX3ACVlfPFXyh4vl9degjM7227 intact-crc:927650F8868A0E0E|rigid:mQ6otKE+ovIH8AWimfBW/yrAwEU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P52172 uniprotkb:Q9W349 intact:EBI-668886|uniprotkb:Q6NMW1|uniprotkb:Q7K0H5|uniprotkb:Q8INC6|uniprotkb:Q94884|uniprotkb:Q9VF01|ensemblmetazoa:FBpp0082669 intact:EBI-102646|uniprotkb:Q24183|uniprotkb:Q9NHX9|ensemblmetazoa:FBpp0071255 psi-mi:srp_drome(display_long)|uniprotkb:GATA-binding factor B(gene name synonym)|uniprotkb:Transcription factor GATA-B(gene name synonym)|uniprotkb:dGATA-B(gene name synonym)|uniprotkb:Protein serpent(gene name synonym)|uniprotkb:srp(gene name)|psi-mi:srp(display_short)|uniprotkb:ABF(gene name synonym)|uniprotkb:CG3992(orf name) psi-mi:lozen_drome(display_long)|uniprotkb:lz(gene name)|psi-mi:lz(display_short)|uniprotkb:CG1689(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873562 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027190.1|refseq:NP_732098.1|refseq:NP_732100.2|flybase:FBgn0003507|refseq:NP_001262618.1|ensemblmetazoa:FBgn0003507(gene)|ensemblmetazoa:FBtr0083215(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007492"(endoderm development)|go:"GO:0007494"(midgut development)|go:"GO:0007503"(fat body development)|go:"GO:0007516"(hemocyte development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042690"(negative regulation of crystal cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046665"(amnioserosa maintenance)|go:"GO:0048542"(lymph gland development)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|reactome:R-DME-5689880|reactome:R-DME-8939236|reactome:R-DME-9018519|reactome:R-DME-983231 refseq:NP_511099.2|flybase:FBgn0002576|ensemblmetazoa:FBgn0002576(gene)|ensemblmetazoa:FBtr0071320(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007469"(antennal development)|go:"GO:0007486"(imaginal disc-derived female genitalia development)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035163"(embryonic hemocyte differentiation)|go:"GO:0035165"(embryonic crystal cell differentiation)|go:"GO:0035168"(larval lymph gland hemocyte differentiation)|go:"GO:0035211"(spermathecum morphogenesis)|go:"GO:0035314"(scab formation)|go:"GO:0042060"(wound healing)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045467"(R7 cell development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048592"(eye morphogenesis)|go:"GO:0048749"(compound eye development)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|reactome:R-DME-549127|reactome:R-DME-8878166|reactome:R-DME-8931987|reactome:R-DME-8934593|reactome:R-DME-8936459|reactome:R-DME-8939236|reactome:R-DME-8939243|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-DME-8939246|reactome:R-DME-8939247|reactome:R-DME-8939245|reactome:R-DME-8939902|reactome:R-DME-8940973|reactome:R-DME-8941326|reactome:R-DME-9018519 pubmed:14657024(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:oi8aA2pnZhIBw3UzV+zfcd2B1KY7227 rogid:y0EC6Q0MIEnXPovp3SsUU8JOQSY7227 intact-crc:D16D46BDD5490271|rigid:Gj+qsVvelcX+J068Pi49KwUY5m8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24107 uniprotkb:P42003 intact:EBI-870126 intact:EBI-162238|uniprotkb:Q9VQM3|ensemblmetazoa:FBpp0077302 psi-mi:q24107_drome(display_long)|uniprotkb:shn(gene name)|psi-mi:shn(display_short)|uniprotkb:CG7734(orf name) psi-mi:mad_drome(display_long)|uniprotkb:Mad(gene name)|psi-mi:Mad(display_short)|uniprotkb:CG12399(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873566 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0003396|go:"GO:0003676"(nucleic acid binding)|go:"GO:0007398"(ectoderm development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048813"(dendrite morphogenesis)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236 refseq:NP_477017.1|flybase:FBgn0011648|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007419"(ventral cord development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007560"(imaginal disc morphogenesis)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0009653"(anatomical structure morphogenesis)|ensemblmetazoa:FBgn0011648(gene)|ensemblmetazoa:FBtr0077616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035290"(trunk segmentation)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060799"(transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|rcsb pdb:3DIT|reactome:R-DME-201451|reactome:R-DME-8941326|rcsb pdb:3GMJ|dip:DIP-18256N pubmed:11071761(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:zSDXPidjbpouBPvovgHbNab6ybY7227 rogid:WIV5vzeVJTr8sKiZNxHA9qmPahE7227 intact-crc:52060DDC2A1DF60B|rigid:Y4YCSlbnAMWLA9dO+ZBdZhL0fW0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O01368 uniprotkb:P42003 intact:EBI-868028 intact:EBI-162238|uniprotkb:Q9VQM3|ensemblmetazoa:FBpp0077302 psi-mi:o01368_drome(display_long)|uniprotkb:nej(gene name)|psi-mi:nej(display_short)|uniprotkb:CG15319(orf name) psi-mi:mad_drome(display_long)|uniprotkb:Mad(gene name)|psi-mi:Mad(display_short)|uniprotkb:CG12399(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873570 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261617|dip:DIP-41329N|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008347"(glial cell migration)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016573"(histone acetylation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0043971"(histone H3-K18 acetylation)|go:"GO:0043974"(histone H3-K27 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043993"("histone acetyltransferase activity (H3-K18 specific)")|go:"GO:0044017"("histone acetyltransferase activity (H3-K27 specific)")|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0098793"(presynapse)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR038547|interpro:IPR043145|mint:O01368 refseq:NP_477017.1|flybase:FBgn0011648|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007419"(ventral cord development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007560"(imaginal disc morphogenesis)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0009653"(anatomical structure morphogenesis)|ensemblmetazoa:FBgn0011648(gene)|ensemblmetazoa:FBtr0077616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035290"(trunk segmentation)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060799"(transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|rcsb pdb:3DIT|reactome:R-DME-201451|reactome:R-DME-8941326|rcsb pdb:3GMJ|dip:DIP-18256N pubmed:10669739(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:JrQCBD9JpkCR4jgg0/08mthcy5o7227 rogid:WIV5vzeVJTr8sKiZNxHA9qmPahE7227 intact-crc:4BA8C6BE5A42022F|rigid:lkOSNG4aUVnlatFNQy9e5CRqVAU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O61458 uniprotkb:P42003 intact:EBI-870152 intact:EBI-162238|uniprotkb:Q9VQM3|ensemblmetazoa:FBpp0077302 psi-mi:o61458_drome(display_long)|uniprotkb:Med(gene name)|psi-mi:Med(display_short)|uniprotkb:SMAD family member(gene name synonym)|uniprotkb:CG1775(orf name) psi-mi:mad_drome(display_long)|uniprotkb:Mad(gene name)|psi-mi:Mad(display_short)|uniprotkb:CG12399(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873574 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0011655|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005737"(cytoplasm)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0046872"(metal ion binding)|go:"GO:0048666"(neuron development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071144"(heteromeric SMAD protein complex)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578 refseq:NP_477017.1|flybase:FBgn0011648|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007419"(ventral cord development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007560"(imaginal disc morphogenesis)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0009653"(anatomical structure morphogenesis)|ensemblmetazoa:FBgn0011648(gene)|ensemblmetazoa:FBtr0077616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035290"(trunk segmentation)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060799"(transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|rcsb pdb:3DIT|reactome:R-DME-201451|reactome:R-DME-8941326|rcsb pdb:3GMJ|dip:DIP-18256N pubmed:9693372(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:gMHOZFYgbFoV30NNGwcqD42yUTQ7227 rogid:WIV5vzeVJTr8sKiZNxHA9qmPahE7227 intact-crc:186AC89858E7BF01|rigid:0Ah19u3Cb9pLkLKAfxnBOk8XeXw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P48555 uniprotkb:Q8SX30 intact:EBI-115197|uniprotkb:Q540X1|ensemblmetazoa:FBpp0070558|ensemblmetazoa:FBpp0070559|uniprotkb:Q9W4Q6 intact:EBI-496977|ensemblmetazoa:FBpp0071559 psi-mi:rala_drome(display_long)|uniprotkb:Rala(gene name)|psi-mi:Rala(display_short)|uniprotkb:CG2849(orf name) psi-mi:q8sx30_drome(display_long)|uniprotkb:CG30388(orf name)|uniprotkb:Magi(gene name)|psi-mi:Magi(display_short)|uniprotkb:CG4117(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873578 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0015286(gene)|ensemblmetazoa:FBtr0070583(transcript)|ensemblmetazoa:FBtr0070584(transcript)|go:"GO:0003924"(GTPase activity)|rcsb pdb:5CM9|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0019003"(GDP binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0090543"(Flemming body)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|rcsb pdb:5CM8|refseq:NP_525063.1|refseq:NP_726882.1|flybase:FBgn0015286|dip:DIP-19199N flybase:FBgn0034590|ensemblmetazoa:FBgn0034590(gene)|ensemblmetazoa:FBtr0071636(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007165"(signal transduction)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0035329"(hippo signaling)|go:"GO:0043195"(terminal bouton)|go:"GO:0097482"(muscle cell postsynaptic specialization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034 pubmed:14516694(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:sTSyV5P4zR3/IGjwg6Ov0YFUl6g7227 rogid:JswSXbr6I8NnUgkMJIojqOUe+XI7227 intact-crc:7A33E32DA8272377|rigid:iLp3TVkK3J2bwHgBbdlCiNaaycs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9V535 uniprotkb:P49028 intact:EBI-172458|uniprotkb:Q8SZA6|uniprotkb:Q95X08|ensemblmetazoa:FBpp0087648 intact:EBI-159609|uniprotkb:Q9W2L3|ensemblmetazoa:FBpp0071497 psi-mi:rbm8a_drome(display_long)|uniprotkb:tsu(gene name)|psi-mi:tsu(display_short)|uniprotkb:Y14(gene name synonym)|uniprotkb:CG8781(orf name)|uniprotkb:Protein tsunagi(gene name synonym) psi-mi:mgn_drome(display_long)|uniprotkb:mago(gene name)|psi-mi:mago(display_short)|uniprotkb:mgn(gene name synonym)|uniprotkb:CG9401(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873582 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610454.2|flybase:FBgn0033378|dip:DIP-24075N|ensemblmetazoa:FBgn0033378(gene)|ensemblmetazoa:FBtr0088567(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000335"(negative regulation of transposition, DNA-mediated)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0008380"(RNA splicing)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046595"(establishment of pole plasm mRNA localization)|go:"GO:0051028"(mRNA transport)|go:"GO:0051663"(oocyte nucleus localization involved in oocyte dorsal/ventral axis specification)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR008111(RNA binding motif protein 8)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033744|interpro:IPR035979|rcsb pdb:1HL6|rcsb pdb:1OO0|rcsb pdb:1RK8|rcsb pdb:2X1G|reactome:R-DME-159236|reactome:R-DME-72163|reactome:R-DME-72187|reactome:R-DME-73856|reactome:R-DME-975957|interpro:IPR000504(RNA recognition motif, RNP-1) ensemblmetazoa:FBgn0002736(gene)|go:"GO:0045495"(pole plasm)|go:"GO:0046594"(maintenance of pole plasm mRNA location)|go:"GO:0048477"(oogenesis)|refseq:NP_476636.1|flybase:FBgn0002736|ensemblmetazoa:FBtr0071569(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000335"(negative regulation of transposition, DNA-mediated)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008104"(protein localization)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0045451"(pole plasm oskar mRNA localization)|interpro:IPR036605|rcsb pdb:1HL6|rcsb pdb:1OO0|rcsb pdb:1RK8|rcsb pdb:2X1G|reactome:R-DME-159236|reactome:R-DME-72163|reactome:R-DME-72187|reactome:R-DME-73856|go:"GO:0051028"(mRNA transport)|reactome:R-DME-975957|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004023(Mago nashi protein)|dip:DIP-23439N pubmed:11696323(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:mvXuoJybAPzkpZyxC85aOArJdDQ7227 rogid:em15spP6qWeChwVDIbDeN5OqtGU7227 intact-crc:7AFF99C70FBB380F|rigid:kU5tJ8Y26sp9fOlYh7Y5u0/IYrg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8WS23 uniprotkb:Q8MQW7 intact:EBI-870047 intact:EBI-868875|ensemblmetazoa:FBpp0083850 psi-mi:q8ws23_drome(display_long)|uniprotkb:rols(gene name)|psi-mi:rols(display_short)|uniprotkb:rols6(gene name synonym)|uniprotkb:CG32096(orf name) psi-mi:q8mqw7_drome(display_long)|uniprotkb:mbc(gene name)|psi-mi:mbc(display_short)|uniprotkb:CG10379(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873586 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0041096|go:"GO:0005737"(cytoplasm)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016740"(transferase activity)|go:"GO:0030018"(Z disc)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0061327"(anterior Malpighian tubule development)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002110(Ankyrin)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770 flybase:FBgn0015513|ensemblmetazoa:FBgn0015513(gene)|ensemblmetazoa:FBtr0084459(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007417"(central nervous system development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007523"(larval visceral muscle development)|go:"GO:0016203"(muscle attachment)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0061327"(anterior Malpighian tubule development)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR026791|interpro:IPR027357|interpro:IPR043161|interpro:IPR043162 pubmed:11709190(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:liZ6VBX2yzld6LPOkXv5Ro19rKY7227 rogid:WKK1nlVkrBUJBbPvHxb3al9gc+07227 intact-crc:8A5485F4E57F8558|rigid:bk4+H/YWcIpCD1MwOqzCjocNy/I false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40792 uniprotkb:Q8MQW7 intact:EBI-74845|uniprotkb:Q9W0H7|ensemblmetazoa:FBpp0072614|ensemblmetazoa:FBpp0304252 intact:EBI-868875|ensemblmetazoa:FBpp0083850 psi-mi:rac1_drome(display_long)|uniprotkb:Rac1(gene name)|psi-mi:Rac1(display_short)|uniprotkb:RacA(gene name synonym)|uniprotkb:CG2248(orf name) psi-mi:q8mqw7_drome(display_long)|uniprotkb:mbc(gene name)|psi-mi:mbc(display_short)|uniprotkb:CG10379(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873590 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476950.1|flybase:FBgn0010333|refseq:NP_001261247.1|ensemblmetazoa:FBgn0010333(gene)|ensemblmetazoa:FBtr0072730(transcript)|ensemblmetazoa:FBtr0331868(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002433"(immune response-regulating cell surface receptor signaling pathway involved in phagocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007394"(dorsal closure, elongation of leading edge cells)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007516"(hemocyte development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007613"(memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008258"(head involution)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0016028"(rhabdomere)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016203"(muscle attachment)|go:"GO:0016358"(dendrite development)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035010"(encapsulation of foreign target)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0035320"(imaginal disc-derived wing hair site selection)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048675"(axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0055001"(muscle cell development)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097206"(nephrocyte filtration)|go:"GO:0110125"(negative regulation of myotube cell migration)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1903391"(regulation of adherens junction organization)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-1433557|reactome:R-DME-193648|reactome:R-DME-2029482|reactome:R-DME-2871796|reactome:R-DME-350376|reactome:R-DME-376172|reactome:R-DME-389359|reactome:R-DME-3928662|reactome:R-DME-3928664|reactome:R-DME-3928665|reactome:R-DME-399954|reactome:R-DME-4086400|reactome:R-DME-4420097|reactome:R-DME-445144|reactome:R-DME-5218920|reactome:R-DME-5625740|reactome:R-DME-5627123|reactome:R-DME-5663213|reactome:R-DME-5687128|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-9013407|reactome:R-DME-9706019|reactome:R-DME-983231 flybase:FBgn0015513|ensemblmetazoa:FBgn0015513(gene)|ensemblmetazoa:FBtr0084459(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007417"(central nervous system development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007523"(larval visceral muscle development)|go:"GO:0016203"(muscle attachment)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0061327"(anterior Malpighian tubule development)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR026791|interpro:IPR027357|interpro:IPR043161|interpro:IPR043162 pubmed:9808621(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:nVrsdRuWmYjJp67rd4Es0mFDuUU7227 rogid:WKK1nlVkrBUJBbPvHxb3al9gc+07227 intact-crc:BFC85F4D151A9748|rigid:K+2fFRt6lU65eQRKrErFxMJ6qK8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O96660 uniprotkb:O61458 intact:EBI-145058|ensemblmetazoa:FBpp0071140|ensemblmetazoa:FBpp0309145 intact:EBI-870152 psi-mi:o96660_drome(display_long)|uniprotkb:Smox(gene name)|psi-mi:Smox(display_short)|uniprotkb:smad2(gene name synonym)|uniprotkb:CG2262(orf name)|uniprotkb:SMAD family member(gene name synonym)|uniprotkb:DSMAD2(gene name synonym)|uniprotkb:DSmad2(gene name synonym)|uniprotkb:Dmel\CG2262(gene name synonym)|uniprotkb:SMAD2(gene name synonym)|uniprotkb:SMOX(gene name synonym)|uniprotkb:Sad(gene name synonym)|uniprotkb:Smad(gene name synonym)|uniprotkb:Smad2(gene name synonym)|uniprotkb:SmoX(gene name synonym)|uniprotkb:dSMAD2(gene name synonym)|uniprotkb:dSmad2(gene name synonym)|uniprotkb:dsmad2(gene name synonym)|uniprotkb:"l(1)G0348"(gene name synonym)|uniprotkb:sad(gene name synonym)|uniprotkb:smox(gene name synonym)|uniprotkb:ted(gene name synonym)|uniprotkb:tmp(gene name synonym)|uniprotkb:Dmel_CG2262(orf name) psi-mi:o61458_drome(display_long)|uniprotkb:Med(gene name)|psi-mi:Med(display_short)|uniprotkb:SMAD family member(gene name synonym)|uniprotkb:CG1775(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873606 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511079.1|flybase:FBgn0025800|refseq:NP_001285006.1|ensemblmetazoa:FBgn0025800(gene)|ensemblmetazoa:FBtr0071192(transcript)|ensemblmetazoa:FBtr0340159(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010507"(negative regulation of autophagy)|dip:DIP-18259N|go:"GO:0016319"(mushroom body development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0044719"(regulation of imaginal disc-derived wing size)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048666"(neuron development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090256"(regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|reactome:R-DME-1181150|reactome:R-DME-1502540|reactome:R-DME-2173788|reactome:R-DME-2173789|reactome:R-DME-2173795|reactome:R-DME-2173796|reactome:R-DME-8941855|reactome:R-DME-9617828 flybase:FBgn0011655|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005737"(cytoplasm)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0046872"(metal ion binding)|go:"GO:0048666"(neuron development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071144"(heteromeric SMAD protein complex)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578 pubmed:10320478(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Yp3zkP2CIw7h2/zcG0RD6D6JivE7227 rogid:gMHOZFYgbFoV30NNGwcqD42yUTQ7227 intact-crc:E772A43E114E6F74|rigid:hejjHCn9ULC354aAh3K44L8aPIc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7YTZ1 uniprotkb:Q24087 intact:EBI-870194|uniprotkb:B7Z0D2|ensemblmetazoa:FBpp0288968 intact:EBI-663297|uniprotkb:Q8IHB9|uniprotkb:Q9W4L3|ensemblmetazoa:FBpp0070624|ensemblmetazoa:FBpp0310174 psi-mi:q7ytz1_drome(display_long)|uniprotkb:mus312(gene name)|psi-mi:mus312(display_short)|uniprotkb:mus312-RD(gene name synonym)|uniprotkb:Dmel_CG8601(orf name)|uniprotkb:Dmel\CG8601(gene name synonym)|uniprotkb:MUS312(gene name synonym)|uniprotkb:"mus(3)312"(gene name synonym)|uniprotkb:CG8601(orf name) psi-mi:xpf_drome(display_long)|uniprotkb:Protein meiotic 9(gene name synonym)|uniprotkb:mei-9(gene name)|psi-mi:mei-9(display_short)|uniprotkb:CG3697(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873610 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0002909|refseq:NP_001137902.1|ensemblmetazoa:FBgn0002909(gene)|ensemblmetazoa:FBtr0299690(transcript) refseq:NP_525068.1|flybase:FBgn0002707|refseq:NP_001284859.1|ensemblmetazoa:FBgn0002707(gene)|ensemblmetazoa:FBtr0070656(transcript)|ensemblmetazoa:FBtr0343574(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000110"(nucleotide-excision repair factor 1 complex)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006296"(nucleotide-excision repair, DNA incision, 5'-to lesion)|go:"GO:0006298"(mismatch repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0030716"(oocyte fate determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1901255"(nucleotide-excision repair involved in interstrand cross-link repair)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR006167(DNA repair protein)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|reactome:R-DME-5696395|reactome:R-DME-5696400|reactome:R-DME-6782135|go:"GO:0003697"(single-stranded DNA binding) pubmed:12504024(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Px5fSPN5YzmK2jGCbs90ytOYOZQ7227 rogid:bNXw/9Wdy694IPTd+ddBCdbsvfk7227 intact-crc:CC23260604E1265C|rigid:lbPBk3ncl1EmoNpP2MvUTb+E2WI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24141 uniprotkb:Q24141 intact:EBI-183986|ensemblmetazoa:FBpp0071675|ensemblmetazoa:FBpp0309743 intact:EBI-183986|ensemblmetazoa:FBpp0071675|ensemblmetazoa:FBpp0309743 psi-mi:sgo1_drome(display_long)|uniprotkb:mei-S332(gene name)|psi-mi:mei-S332(display_short)|uniprotkb:CG5303(orf name)|uniprotkb:Meiotic protein S332(gene name synonym) psi-mi:sgo1_drome(display_long)|uniprotkb:mei-S332(gene name)|psi-mi:mei-S332(display_short)|uniprotkb:CG5303(orf name)|uniprotkb:Meiotic protein S332(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873614 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476634.1|flybase:FBgn0002715|refseq:NP_001286705.1|dip:DIP-17412N|ensemblmetazoa:FBgn0002715(gene)|ensemblmetazoa:FBtr0071761(transcript)|ensemblmetazoa:FBtr0342979(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007065"(male meiosis sister chromatid cohesion)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|interpro:IPR011515(Shugoshin, C-terminal)|interpro:IPR011516(Shugoshin, N-terminal) refseq:NP_476634.1|flybase:FBgn0002715|refseq:NP_001286705.1|dip:DIP-17412N|ensemblmetazoa:FBgn0002715(gene)|ensemblmetazoa:FBtr0071761(transcript)|ensemblmetazoa:FBtr0342979(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007065"(male meiosis sister chromatid cohesion)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|interpro:IPR011515(Shugoshin, C-terminal)|interpro:IPR011516(Shugoshin, N-terminal) pubmed:9869638(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Y7NZIBor9Nu7SCUO74sK3MHs2ww7227 rogid:Y7NZIBor9Nu7SCUO74sK3MHs2ww7227 intact-crc:F13A2CFED501DB2D|rigid:r03vP8oSQeD+yPnhGmvDJGke8BQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O61443 uniprotkb:Q8MSQ4 intact:EBI-82330|ensemblmetazoa:FBpp0080111 intact:EBI-870203|ensemblmetazoa:FBpp0083099 psi-mi:mk38b_drome(display_long)|uniprotkb:p38b(gene name)|psi-mi:p38b(display_short)|uniprotkb:CG7393(orf name) psi-mi:q8msq4_drome(display_long)|uniprotkb:dMEKK1(gene name synonym)|uniprotkb:Dmel\CG7717(gene name synonym)|uniprotkb:MEKK(gene name synonym)|uniprotkb:MEKK1(gene name synonym)|uniprotkb:MEKK4(gene name synonym)|uniprotkb:dMEKK(gene name synonym)|uniprotkb:D-MEKK1(gene name synonym)|uniprotkb:4(gene name synonym)|uniprotkb:D-Mekk1(gene name synonym)|uniprotkb:DmMEKK1(gene name synonym)|uniprotkb:dMEKK4(gene name synonym)|uniprotkb:Mekk1(gene name)|psi-mi:Mekk1(display_short)|uniprotkb:mekk1(gene name synonym)|uniprotkb:dMekk1(gene name synonym)|uniprotkb:mekk1a(gene name synonym)|uniprotkb:mekk1b(gene name synonym)|uniprotkb:Dmel_CG7717(orf name)|uniprotkb:CG7717(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873618 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477361.1|flybase:FBgn0024846|go:"GO:0001934"(positive regulation of protein phosphorylation)|ensemblmetazoa:FBgn0024846(gene)|ensemblmetazoa:FBtr0080534(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0009617"(response to bacterium)|go:"GO:0009651"(response to salt stress)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038001"(paracrine signaling)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042594"(response to starvation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048082"(regulation of adult chitin-containing cuticle pigmentation)|go:"GO:0050832"(defense response to fungus)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-168638|reactome:R-DME-171007|reactome:R-DME-198753|reactome:R-DME-2559580|reactome:R-DME-376172|reactome:R-DME-418592|reactome:R-DME-432142|reactome:R-DME-4420097|reactome:R-DME-450302|reactome:R-DME-450341|reactome:R-DME-525793|reactome:R-DME-5675221|reactome:R-DME-6798695|dip:DIP-22779N refseq:NP_732373.1|flybase:FBgn0024329|dip:DIP-61848N|ensemblmetazoa:FBgn0024329(gene)|ensemblmetazoa:FBtr0083684(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002385"(mucosal immune response)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031452"(negative regulation of heterochromatin assembly)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071475"(cellular hyperosmotic salinity response)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-5607761|reactome:R-DME-5668541|reactome:R-DME-5676590|go:"GO:0034605"(cellular response to heat) pubmed:11574474(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:rkuVJJgL+rmuXx8eEMG3/tjP8tE7227 rogid:jrb8uK835Q/cxOH0Znp+4prVZOQ7227 intact-crc:EF3BA30E5E47D1BB|rigid:R/i62/7ZAJUGhDZN3oUiCX9Q2Kc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O02194 uniprotkb:Q86BS6 intact:EBI-255741|uniprotkb:O02395|uniprotkb:O76802|uniprotkb:O96340|uniprotkb:Q9TY80|uniprotkb:Q9V3L9|uniprotkb:Q9V3S1|ensemblmetazoa:FBpp0077850|ensemblmetazoa:FBpp0305666 intact:EBI-220604|uniprotkb:Q960S9|uniprotkb:Q9W0C0|ensemblmetazoa:FBpp0072696 psi-mi:psn_drome(display_long)|uniprotkb:Psn(gene name)|psi-mi:Psn(display_short)|uniprotkb:PS(gene name synonym)|uniprotkb:CG18803(orf name)|uniprotkb:dPS(gene name synonym) psi-mi:metl_drome(display_long)|uniprotkb:metl(gene name)|psi-mi:metl(display_short)|uniprotkb:CG13929(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873622 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0284421|refseq:NP_524184.1|refseq:NP_730535.1|refseq:NP_001262110.1|refseq:NP_001262111.1|dip:DIP-1139N|ensemblmetazoa:FBgn0284421(gene)|ensemblmetazoa:FBtr0078192(transcript)|ensemblmetazoa:FBtr0333479(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006508"(proteolysis)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0009986"(cell surface)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030018"(Z disc)|go:"GO:0030426"(growth cone)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035333"(Notch receptor processing, ligand-dependent)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0070765"(gamma-secretase complex)|interpro:IPR001108(Peptidase A22A, presenilin)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR042524|reactome:R-DME-1251985|reactome:R-DME-3928665|reactome:R-DME-6798695 refseq:NP_647636.3|refseq:NP_728647.2|flybase:FBgn0035247|ensemblmetazoa:FBgn0035247(gene)|ensemblmetazoa:FBtr0072814(transcript)|go:"GO:0016427"("tRNA (cytosine) methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0052735"("tRNA (cytosine-3-)-methyltransferase activity")|interpro:IPR026113|interpro:IPR029063|interpro:IPR041698 pubmed:11738826(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:UZooKoj+G0I4jZIcHgX+55Nlw887227 rogid:JJxv8S3deRbaT6VQRmmn6MqhU0I7227 intact-crc:802C7548BC630C7B|rigid:tWQOuK8qmIXwvZrR4RD48RTPg80 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9I7U4 uniprotkb:P05661 intact:EBI-867591|uniprotkb:O76275|uniprotkb:O76276|uniprotkb:O76277|uniprotkb:O76278|uniprotkb:O96767|uniprotkb:O96768|uniprotkb:Q7KA82|uniprotkb:Q7KAJ1|uniprotkb:Q7KPQ8|uniprotkb:Q7RTL4|uniprotkb:Q8T3N3|uniprotkb:Q9N2P7|uniprotkb:Q9N680|uniprotkb:Q9N9Y5|uniprotkb:Q9N9Y6|uniprotkb:Q9N9Y7|uniprotkb:Q9NFS3|uniprotkb:Q9NJP4|uniprotkb:Q9NL88|uniprotkb:Q9UB79|uniprotkb:Q9W055|uniprotkb:Q9XZT9|ensemblmetazoa:FBpp0072727|ensemblmetazoa:FBpp0304925 intact:EBI-195031|uniprotkb:O18392|uniprotkb:O18393|uniprotkb:Q24412|uniprotkb:Q7JN62|uniprotkb:Q7JN63|uniprotkb:Q7JQ08|uniprotkb:Q7JQ09|uniprotkb:Q7M4K4|uniprotkb:Q8INZ9|uniprotkb:Q8IP00|uniprotkb:Q8IP01|uniprotkb:Q8IP02|uniprotkb:Q8IP03|uniprotkb:Q8IP04|uniprotkb:Q8IP05|uniprotkb:Q8IP06|uniprotkb:Q8IP07|uniprotkb:Q8IP08|uniprotkb:Q8IP09|uniprotkb:Q8IP10|uniprotkb:Q9TY21|uniprotkb:Q9TY22|uniprotkb:Q9TYD7|uniprotkb:Q9VJI3 psi-mi:titin_drome(display_long)|uniprotkb:D-Titin(gene name synonym)|uniprotkb:Kettin(gene name synonym)|uniprotkb:sls(gene name)|psi-mi:sls(display_short)|uniprotkb:titin(gene name synonym)|uniprotkb:CG1915(orf name) psi-mi:mysa_drome(display_long)|uniprotkb:Mhc(gene name)|psi-mi:Mhc(display_short)|uniprotkb:CG17927(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873626 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524676.2|flybase:FBgn0086906|ensemblmetazoa:FBgn0086906(gene)|ensemblmetazoa:FBtr0072848(transcript)|ensemblmetazoa:FBtr0332679(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003779"(actin binding)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007498"(mesoderm development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016203"(muscle attachment)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0031674"(I band)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0040011"(locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051301"(cell division)|interpro:IPR001452(Src homology-3)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010939(Protein of unknown function DUF1136)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|reactome:R-DME-5658623 refseq:NP_001162991.1|refseq:NP_523587.4|refseq:NP_723999.1|refseq:NP_724000.1|refseq:NP_724001.1|refseq:NP_724003.1|refseq:NP_724004.1|refseq:NP_724005.1|refseq:NP_724006.1|refseq:NP_724007.1|refseq:NP_724008.1|refseq:NP_724009.1|refseq:NP_724010.1|refseq:NP_724002.2|flybase:FBgn0264695|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007517"(muscle organ development)|go:"GO:0007527"(adult somatic muscle development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0030017"(sarcomere)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031033"(myosin filament organization)|go:"GO:0031672"(A band)|go:"GO:0040011"(locomotion)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045214"(sarcomere organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060361"(flight)|go:"GO:0071689"(muscle thin filament assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P05661|rcsb pdb:5W1A pubmed:11535621(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KudT+8stWca6bWBIOIHz4zh5mqY7227 rogid:PjIC1oHiwbQEdum3SDZnk/b7O5E7227 intact-crc:E5BEC7C1DCDF275B|rigid:r3ZzhvgAF8hL7nLD97UGXYf6zUQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42282 uniprotkb:O97159 intact:EBI-77008|uniprotkb:A4V3Q3|uniprotkb:Q0KHY0|uniprotkb:Q1LZ43|uniprotkb:Q24313|uniprotkb:Q9V9V2|ensemblmetazoa:FBpp0085186|ensemblmetazoa:FBpp0085188|ensemblmetazoa:FBpp0085190|ensemblmetazoa:FBpp0292319 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 psi-mi:ttka_drome(display_long)|uniprotkb:ttk(gene name)|psi-mi:ttk(display_short)|uniprotkb:FTZ-F2(gene name synonym)|uniprotkb:CG1856(orf name)|uniprotkb:Tramtrack p88(gene name synonym)|uniprotkb:Repressor protein fushi tarazu(gene name synonym) psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873630 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189329.1|refseq:NP_733443.1|refseq:NP_733444.1|refseq:NP_733445.1|flybase:FBgn0003870|ensemblmetazoa:FBgn0003870(gene)|ensemblmetazoa:FBtr0085825(transcript)|ensemblmetazoa:FBtr0085827(transcript)|ensemblmetazoa:FBtr0085829(transcript)|ensemblmetazoa:FBtr0303227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031208"(POZ domain binding)|go:"GO:0035001"(dorsal trunk growth, open tracheal system)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035151"(regulation of tube size, open tracheal system)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042682"(regulation of compound eye cone cell fate specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045677"(negative regulation of R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048053"(R1/R6 development)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048750"(compound eye corneal lens morphogenesis)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724 pubmed:11743021(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:k0MeF2/ch3ddqz7uLHjP8aeJwoI7227 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 intact-crc:AA7A15E9E23CE23E|rigid:Pxpk9ecS/8hAp52TNl/ntg/CLkE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O96681 uniprotkb:Q86BA1 intact:EBI-870234 intact:EBI-107489|uniprotkb:Q9VH41|intact:EBI-2890407|intact:EBI-3423396|intact:EBI-498102|uniprotkb:B7Z0U5|uniprotkb:F2FB99|uniprotkb:Q86BA2|uniprotkb:Q86BA3|uniprotkb:Q8MTA1|uniprotkb:Q8MUJ8|uniprotkb:Q8MUJ9|uniprotkb:Q8MUK0|intact:EBI-9966258|intact:EBI-9920983|intact:EBI-870219|intact:EBI-3431449|ensemblmetazoa:FBpp0081687|ensemblmetazoa:FBpp0081688|ensemblmetazoa:FBpp0081690|ensemblmetazoa:FBpp0081691 psi-mi:o96681_drome(display_long)|uniprotkb:PlexA(gene name)|psi-mi:PlexA(display_short)|uniprotkb:plexA(gene name synonym)|uniprotkb:CG11081(orf name) psi-mi:mical_drome(display_long)|uniprotkb:Mical(gene name)|psi-mi:Mical(display_short)|uniprotkb:Molecule interacting with CasL protein homolog(gene name synonym)|uniprotkb:CG33208(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873634 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0025741|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0030250"(guanylate cyclase activator activity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097374"(sensory neuron axon guidance)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:2000305"(semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362 flybase:FBgn0053208|refseq:NP_788622.1|refseq:NP_788623.1|refseq:NP_788624.1|refseq:NP_788625.1|refseq:NP_788626.2|refseq:NP_001138032.1|refseq:NP_788620.1|refseq:NP_788621.1|refseq:NP_788627.1|dip:DIP-61753N|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030047"(actin modification)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031941"(filamentous actin)|go:"GO:0043195"(terminal bouton)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060386"(synapse assembly involved in innervation)|go:"GO:0071949"(FAD binding)|go:"GO:1904799"(regulation of neuron remodeling)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR022735|interpro:IPR036188|interpro:IPR036872|ensemblmetazoa:FBgn0053208(gene)|ensemblmetazoa:FBtr0082209(transcript)|ensemblmetazoa:FBtr0082210(transcript)|ensemblmetazoa:FBtr0082212(transcript)|ensemblmetazoa:FBtr0082213(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0007411"(axon guidance)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen") pubmed:12110185(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+9+nmrm+OrwkG/mEh1tqH0IC5C47227 rogid:DSZEZQLHL41Txz8pHo0HUmdKzjM7227 intact-crc:88D51A720848A9FD|rigid:v4fGlLKcUCfa/9JXZsYkii6filQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P25159 uniprotkb:O44224 intact:EBI-179533|intact:EBI-1630222|uniprotkb:Q6NQY8|uniprotkb:Q86PB7|uniprotkb:Q9V8B8|uniprotkb:Q9V8B9|ensemblmetazoa:FBpp0085962 intact:EBI-869852 psi-mi:stau_drome(display_long)|uniprotkb:stau(gene name)|psi-mi:stau(display_short)|uniprotkb:CG5753(orf name) psi-mi:o44224_drome(display_long)|uniprotkb:mira(gene name)|psi-mi:mira(display_short)|uniprotkb:CG12249(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873638 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163185.1|refseq:NP_476751.1|refseq:NP_725748.1|flybase:FBgn0003520|ensemblmetazoa:FBgn0003520(gene)|ensemblmetazoa:FBtr0086783(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006403"(RNA localization)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007316"(pole plasm RNA localization)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007616"(long-term memory)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045180"(basal cortex)|go:"GO:0045450"(bicoid mRNA localization)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046011"(regulation of oskar mRNA translation)|go:"GO:0048477"(oogenesis)|go:"GO:0060293"(germ plasm)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|rcsb pdb:1EKZ|rcsb pdb:1STU|rcsb pdb:5CFF flybase:FBgn0021776|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005938"(cell cortex)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007402"(ganglion mother cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007419"(ventral cord development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045178"(basal part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045180"(basal cortex)|go:"GO:0048477"(oogenesis)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0072697"(protein localization to cell cortex) pubmed:9637686(see-also)|pubmed:9735369(see-also)|pubmed:9888987(see-also)|pubmed:9637685(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8wlpvhd3GYYnc2+hayn2HjsYQ0A7227 rogid:BJlUYvSh2EVnA0PxNbeFipc/S207227 intact-crc:290E740A510E54CC|rigid:m3KDCG1V3MViXlM7KzVxvwwqizo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P29617 uniprotkb:O44224 intact:EBI-213350|uniprotkb:Q95SP0|uniprotkb:Q9U6A2|uniprotkb:Q9VGP8|uniprotkb:Q6AWI5|uniprotkb:A0A0B4K660|ensemblmetazoa:FBpp0293150 intact:EBI-869852 psi-mi:pros_drome(display_long)|uniprotkb:pros(gene name)|psi-mi:pros(display_short)|uniprotkb:CG17228(orf name) psi-mi:o44224_drome(display_long)|uniprotkb:mira(gene name)|psi-mi:mira(display_short)|uniprotkb:CG12249(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873642 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001247046.1|refseq:NP_524317.4|refseq:NP_731565.4|refseq:NP_788636.3|flybase:FBgn0004595|ensemblmetazoa:FBgn0004595(gene)|ensemblmetazoa:FBtr0304608(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007402"(ganglion mother cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014016"(neuroblast differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045179"(apical cortex)|go:"GO:0045180"(basal cortex)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0055060"(asymmetric neuroblast division resulting in ganglion mother cell formation)|go:"GO:0060385"(axonogenesis involved in innervation)|go:"GO:0061564"(axon development)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070983"(dendrite guidance)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR009057(Homeodomain-like)|interpro:IPR023082|interpro:IPR037131|interpro:IPR039350|rcsb pdb:1MIJ|rcsb pdb:1XPX flybase:FBgn0021776|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005938"(cell cortex)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007402"(ganglion mother cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007419"(ventral cord development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045178"(basal part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045180"(basal cortex)|go:"GO:0048477"(oogenesis)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0072697"(protein localization to cell cortex) pubmed:9637685(see-also)|pubmed:9267025(see-also)|pubmed:9403694(see-also)|pubmed:9735369(see-also)|pubmed:9888987(see-also)|pubmed:9403694(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xphiJOfb887AalCF1YoE2OD0DcQ7227 rogid:BJlUYvSh2EVnA0PxNbeFipc/S207227 intact-crc:1969134D1DC9510C|rigid:Q7zzIb613y62Ryeh3+bnR29GQkA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16554 uniprotkb:O44224 intact:EBI-429581|uniprotkb:Q8IPE9|uniprotkb:Q961A6|uniprotkb:Q9VLB8|uniprotkb:B8A413|uniprotkb:B8A419|ensemblmetazoa:FBpp0079420|ensemblmetazoa:FBpp0308609 intact:EBI-869852 psi-mi:numb_drome(display_long)|uniprotkb:CG3779(orf name)|uniprotkb:numb(gene name)|psi-mi:numb(display_short) psi-mi:o44224_drome(display_long)|uniprotkb:mira(gene name)|psi-mi:mira(display_short)|uniprotkb:CG12249(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873646 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523523.2|refseq:NP_723460.1|flybase:FBgn0002973|refseq:NP_001260291.1|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051642"(centrosome localization)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|mint:P16554|go:"GO:0045178"(basal part of cell)|rcsb pdb:1DDM|rcsb pdb:2NMB|rcsb pdb:5YI7|rcsb pdb:5YI8|reactome:R-DME-5610780|reactome:R-DME-5632684|ensemblmetazoa:FBgn0002973(gene)|ensemblmetazoa:FBtr0079822(transcript)|ensemblmetazoa:FBtr0339526(transcript)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005112"(Notch binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008104"(protein localization)|go:"GO:0008347"(glial cell migration)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0045035"(sensory organ precursor cell division) flybase:FBgn0021776|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005938"(cell cortex)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007402"(ganglion mother cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007419"(ventral cord development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045178"(basal part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045180"(basal cortex)|go:"GO:0048477"(oogenesis)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0072697"(protein localization to cell cortex) pubmed:9267025(see-also)|pubmed:9637685(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:9FGhbcAA6k1LCDHPoLSXwEEVwzY7227 rogid:BJlUYvSh2EVnA0PxNbeFipc/S207227 intact-crc:30BA977D0305FBB9|rigid:S7FZuIrUI2IrlB0FfZim6Pl3hRw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O96695 uniprotkb:Q9W4X9 intact:EBI-870247 intact:EBI-165891|ensemblmetazoa:FBpp0070425 psi-mi:o96695_drome(display_long)|uniprotkb:rod(gene name)|psi-mi:rod(display_short)|uniprotkb:CG1569(orf name) psi-mi:zw10_drome(display_long)|uniprotkb:Zw10(gene name)|psi-mi:Zw10(display_short)|uniprotkb:Mitotic 15 protein(gene name synonym)|uniprotkb:"mit(1)15"(gene name synonym)|uniprotkb:CG9900(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873650 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0003268|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005795"(Golgi stack)|go:"GO:0005819"(spindle)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0007030"(Golgi organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0036063"(acroblast)|go:"GO:0051233"(spindle midzone)|go:"GO:1990423"(RZZ complex)|interpro:IPR019527 ensemblmetazoa:FBgn0004643(gene)|ensemblmetazoa:FBtr0070441(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007107"(membrane addition at site of cytokinesis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0031267"(small GTPase binding)|go:"GO:0036063"(acroblast)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0051233"(spindle midzone)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|reactome:R-DME-6811434|refseq:NP_524901.2|flybase:FBgn0004643 pubmed:11590237(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ot0DXOAKlPmfVf8r1O1qDNGt2FY7227 rogid:2g70SyEE4RbzkGOfTrZEG603PT87227 intact-crc:28F2FE4B6BCB4ABF|rigid:sxuIPzHMMMaevxYkY+WZ1xrRWU4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VVW5 uniprotkb:P40417 intact:EBI-870259|uniprotkb:Q95SV1|uniprotkb:Q9VVW4|uniprotkb:Q86P14|ensemblmetazoa:FBpp0074802|ensemblmetazoa:FBpp0305422 intact:EBI-867790|uniprotkb:A0A021WW06|uniprotkb:Q7PL59|uniprotkb:Q9W5M2|uniprotkb:A8Y4W1|uniprotkb:A8Y4W2|uniprotkb:Q9W5M3|ensemblmetazoa:FBpp0112423|ensemblmetazoa:FBpp0112425|ensemblmetazoa:FBpp0112426|ensemblmetazoa:FBpp0311493 psi-mi:dusk3_drome(display_long)|uniprotkb:Mkp3(gene name)|psi-mi:Mkp3(display_short)|uniprotkb:CG14080(orf name)|uniprotkb:Drosophila MKP3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase phosphatase 3(gene name synonym) psi-mi:erka_drome(display_long)|uniprotkb:Extracellular-regulated kinase A(gene name synonym)|uniprotkb:Protein rolled(gene name synonym)|uniprotkb:rl(gene name)|psi-mi:rl(display_short)|uniprotkb:ERKa(gene name synonym)|uniprotkb:CG12559(orf name)|uniprotkb:MAPK(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873654 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_649087.1|refseq:NP_730385.1|flybase:FBgn0036844|refseq:NP_001262032.1|ensemblmetazoa:FBgn0036844(gene)|ensemblmetazoa:FBtr0075035(transcript)|ensemblmetazoa:FBtr0333220(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0002385"(mucosal immune response)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007428"(primary branching, open tracheal system)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008330"(protein tyrosine/threonine phosphatase activity)|go:"GO:0017017"(MAP kinase tyrosine/serine/threonine phosphatase activity)|go:"GO:0033550"(MAP kinase tyrosine phosphatase activity)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001763(Rhodanese-like)|interpro:IPR008343(MAP kinase phosphatase)|interpro:IPR020422|interpro:IPR029021|interpro:IPR036873|reactome:R-DME-112409|reactome:R-DME-202670|reactome:R-DME-5675221 refseq:NP_001015121.3|refseq:NP_001104348.2|refseq:NP_001287635.1|refseq:NP_001015122.1|refseq:NP_001015123.1|refseq:NP_001104349.1|flybase:FBgn0003256|dip:DIP-17266N|ensemblmetazoa:FBgn0003256(gene)|ensemblmetazoa:FBtr0113700(transcript)|ensemblmetazoa:FBtr0113702(transcript)|ensemblmetazoa:FBtr0113703(transcript)|ensemblmetazoa:FBtr0345337(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007362"(terminal region determination)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000826"(regulation of heart morphogenesis)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P40417|reactome:R-DME-110056|reactome:R-DME-112409|reactome:R-DME-112411|reactome:R-DME-1295596|reactome:R-DME-162658|reactome:R-DME-170968|reactome:R-DME-198753|reactome:R-DME-202670|reactome:R-DME-2029482|reactome:R-DME-2559580|reactome:R-DME-2559582|reactome:R-DME-2559585|reactome:R-DME-2871796|reactome:R-DME-3371453|reactome:R-DME-375165|reactome:R-DME-437239|reactome:R-DME-445144|reactome:R-DME-450341|reactome:R-DME-456926|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5654733|reactome:R-DME-5663213|reactome:R-DME-5673001|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5687128|reactome:R-DME-6798695|reactome:R-DME-74749|reactome:R-DME-881907|reactome:R-DME-9634635|reactome:R-DME-9634638 pubmed:14701731(see-also)|pubmed:12810595(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:j3L/XRHHe60qijCAGrgRF1rBxEU7227 rogid:m7w7KhuZSyx3t+dR2TKtvx/vRtA7227 intact-crc:7C8422FE91FABF89|rigid:jTU/VkOKhoyoGP4smYPjkGg33Gs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q961D4 uniprotkb:P18432 intact:EBI-870271 intact:EBI-83734|uniprotkb:Q9VA98|ensemblmetazoa:FBpp0088688 psi-mi:q961d4_drome(display_long)|uniprotkb:Rok(gene name)|psi-mi:Rok(display_short)|uniprotkb:rok(gene name synonym)|uniprotkb:CG9774(orf name) psi-mi:mlr_drome(display_long)|uniprotkb:Mlc2(gene name)|psi-mi:Mlc2(display_short)|uniprotkb:CG2184(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873658 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0026181|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0003384"(apical constriction involved in gastrulation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007302"(nurse cell nucleus anchoring)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007391"(dorsal closure)|go:"GO:0008335"(female germline ring canal stabilization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008544"(epidermis development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032065"(maintenance of protein location in cell cortex)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035191"(nuclear axial expansion)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048599"(oocyte development)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0072518"(Rho-dependent protein serine/threonine kinase activity)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1903035"(negative regulation of response to wounding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015008(Rho Binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020684 ensemblmetazoa:FBgn0002773(gene)|go:"GO:0003012"(muscle system process)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|go:"GO:0060361"(flight)|interpro:IPR002048(Calcium-binding EF-hand)|ensemblmetazoa:FBtr0089747(transcript)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|reactome:R-DME-5627123|refseq:NP_524586.1|flybase:FBgn0002773|dip:DIP-19462N pubmed:11301004(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:mN/LP4s8G6rMOrpeJxUEXLeQsjk7227 rogid:uAnLiMxBEfcweiS/L1nS4M8UGuM7227 intact-crc:1BB3F5134779276E|rigid:mlLh1hbn4zaBYchmrVgoOF0B22A false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VI13 uniprotkb:P18432 intact:EBI-74826|intact:EBI-123979|intact:EBI-466309|uniprotkb:Q24190|uniprotkb:Q24213|ensemblmetazoa:FBpp0081211|ensemblmetazoa:FBpp0081212|ensemblmetazoa:FBpp0081213|ensemblmetazoa:FBpp0306606|ensemblmetazoa:FBpp0306611 intact:EBI-83734|uniprotkb:Q9VA98|ensemblmetazoa:FBpp0088688 psi-mi:pak_drome(display_long)|uniprotkb:Pak(gene name)|psi-mi:Pak(display_short)|uniprotkb:DPAK(gene name synonym)|uniprotkb:Dpak1(gene name synonym)|uniprotkb:CG10295(orf name) psi-mi:mlr_drome(display_long)|uniprotkb:Mlc2(gene name)|psi-mi:Mlc2(display_short)|uniprotkb:CG2184(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873662 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0267698|refseq:NP_001262309.1|refseq:NP_001262313.1|refseq:NP_524681.1|refseq:NP_731073.1|refseq:NP_731074.1|ensemblmetazoa:FBgn0267698(gene)|ensemblmetazoa:FBtr0081714(transcript)|ensemblmetazoa:FBtr0081715(transcript)|ensemblmetazoa:FBtr0081716(transcript)|ensemblmetazoa:FBtr0334539(transcript)|ensemblmetazoa:FBtr0334544(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019991"(septate junction assembly)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936 ensemblmetazoa:FBgn0002773(gene)|go:"GO:0003012"(muscle system process)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|go:"GO:0060361"(flight)|interpro:IPR002048(Calcium-binding EF-hand)|ensemblmetazoa:FBtr0089747(transcript)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|reactome:R-DME-5627123|refseq:NP_524586.1|flybase:FBgn0002773|dip:DIP-19462N pubmed:11322388(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2021/06/18 rogid:B88kI/CaRk7fc0eQ5+Y4jk4zWwc7227 rogid:uAnLiMxBEfcweiS/L1nS4M8UGuM7227 intact-crc:D87EFCCEE3C3722A|rigid:OYp47L6cRLRvNXYY8Fv1NVX8TQ4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q27279 uniprotkb:Q9NKV0 intact:EBI-496967 intact:EBI-172802|uniprotkb:A1ZA61|uniprotkb:A1ZA62|uniprotkb:Q540Y3|uniprotkb:Q8IG90|uniprotkb:Q95P43|uniprotkb:Q9V7G3|ensemblmetazoa:FBpp0089346 psi-mi:q27279_drome(display_long)|uniprotkb:CG6054(orf name)|uniprotkb:"Su(fu)"(gene name)|psi-mi:"Su(fu)"(display_short)|uniprotkb:suppressor of fused(gene name synonym) psi-mi:mlf_drome(display_long)|uniprotkb:Mlf(gene name)|psi-mi:Mlf(display_short)|uniprotkb:CG8295(orf name)|uniprotkb:Myelodysplasia-myeloid leukemia factor(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873666 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0005355|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-DME-209159|reactome:R-DME-216119 refseq:NP_523753.1|refseq:NP_725501.2|refseq:NP_725502.1|refseq:NP_995847.1|flybase:FBgn0034051|ensemblmetazoa:FBgn0034051(gene)|ensemblmetazoa:FBtr0087295(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR019376 pubmed:14622141(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:kJht+zz+5JAYtNJQ1IX1hW480e47227 rogid:KczdABKCmzLycD8vxaBvfphu+EU7227 intact-crc:3C9D31752FC0C18E|rigid:5DEYXvgN6SQFuy0oxk8AP+E/GmQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O01368 uniprotkb:P13469 intact:EBI-868028 intact:EBI-182178|uniprotkb:Q9V9S2|ensemblmetazoa:FBpp0085233|ensemblmetazoa:FBpp0301951 psi-mi:o01368_drome(display_long)|uniprotkb:nej(gene name)|psi-mi:nej(display_short)|uniprotkb:CG15319(orf name) psi-mi:modu_drome(display_long)|uniprotkb:mod(gene name)|psi-mi:mod(display_short)|uniprotkb:CG2050(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873670 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261617|dip:DIP-41329N|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008347"(glial cell migration)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016573"(histone acetylation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0043971"(histone H3-K18 acetylation)|go:"GO:0043974"(histone H3-K27 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043993"("histone acetyltransferase activity (H3-K18 specific)")|go:"GO:0044017"("histone acetyltransferase activity (H3-K27 specific)")|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0098793"(presynapse)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR038547|interpro:IPR043145|mint:O01368 refseq:NP_524614.2|flybase:FBgn0002780|refseq:NP_001247401.1|dip:DIP-19479N|ensemblmetazoa:FBgn0002780(gene)|ensemblmetazoa:FBtr0085874(transcript)|ensemblmetazoa:FBtr0310268(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 pubmed:11854460(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:JrQCBD9JpkCR4jgg0/08mthcy5o7227 rogid:TCYsP4QVbkXfuzyna320LlpH87Y7227 intact-crc:899BF0BEF221C8FC|rigid:iO7h9V8D0fsPJzM0SfiwE9alEjw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08970 uniprotkb:Q86B87 intact:EBI-101373|uniprotkb:Q0KI74|uniprotkb:Q9VFK9|ensemblmetazoa:FBpp0082404|ensemblmetazoa:FBpp0082405|ensemblmetazoa:FBpp0301708 intact:EBI-124784|uniprotkb:A1A725|uniprotkb:A8JR64|uniprotkb:A8JR66|ensemblmetazoa:FBpp0083478|uniprotkb:P91932|uniprotkb:Q24099|uniprotkb:Q24100|uniprotkb:Q24101|uniprotkb:Q24482|uniprotkb:Q24483|uniprotkb:Q86B84|uniprotkb:Q86B85|uniprotkb:Q86B86|uniprotkb:Q8IN28|uniprotkb:Q8IN29|uniprotkb:Q8IN30|uniprotkb:Q8IN31|uniprotkb:Q8IN32|uniprotkb:Q8IN33|uniprotkb:Q8IN34|uniprotkb:Q8WTI9|uniprotkb:Q8WTJ0|uniprotkb:Q8WTJ1|uniprotkb:Q95R78|uniprotkb:Q95ZF4|uniprotkb:Q95ZF5|uniprotkb:Q95ZF6|uniprotkb:Q95ZF7|uniprotkb:Q95ZF8|uniprotkb:Q9N6U6|uniprotkb:Q9N6U7|uniprotkb:Q9N6U8|uniprotkb:Q9N6U9|uniprotkb:Q9N6V0|uniprotkb:Q9N6V1|uniprotkb:Q9N6V2|uniprotkb:Q9N6V3|uniprotkb:Q9N6V4|uniprotkb:Q9N6V5|uniprotkb:Q9N6V6|uniprotkb:Q9N6V7|uniprotkb:Q9N6V8|uniprotkb:Q9N6V9|uniprotkb:Q9N6W0|uniprotkb:Q9N6W1|uniprotkb:Q9N6W2|uniprotkb:Q9N6W3|uniprotkb:Q9N6W4|uniprotkb:Q9N6W5|uniprotkb:Q9VDA9|uniprotkb:Q9VDB2|uniprotkb:Q9VDB3|uniprotkb:Q9VDB4|uniprotkb:Q9VDB5 psi-mi:suhw_drome(display_long)|uniprotkb:"su(Hw)"(gene name)|psi-mi:"su(Hw)"(display_short)|uniprotkb:CG8573(orf name) psi-mi:mmd4_drome(display_long)|uniprotkb:"mod(mdg4)"(gene name)|psi-mi:"mod(mdg4)"(display_short)|uniprotkb:bpd(gene name synonym)|uniprotkb:doom(gene name synonym)|uniprotkb:"E(var)3-93D"(gene name synonym)|uniprotkb:CG32491(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873674 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001247098.1|refseq:NP_524349.1|refseq:NP_731897.1|flybase:FBgn0003567|ensemblmetazoa:FBgn0003567(gene)|ensemblmetazoa:FBtr0082945(transcript)|ensemblmetazoa:FBtr0082946(transcript)|ensemblmetazoa:FBtr0310002(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035075"(response to ecdysone)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1990188"(euchromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P08970|dip:DIP-17895N ensemblmetazoa:FBgn0002781(gene)|ensemblmetazoa:FBtr0084079(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001672"(regulation of chromatin assembly or disassembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007141"(male meiosis I)|go:"GO:0008354"(germ cell migration)|refseq:NP_001097856.1|refseq:NP_001097857.1|refseq:NP_001097858.1|refseq:NP_524936.2|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0031208"(POZ domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|refseq:NP_732619.1|refseq:NP_732620.1|refseq:NP_732621.1|refseq:NP_732622.1|refseq:NP_732624.1|refseq:NP_732625.1|refseq:NP_732626.1|refseq:NP_732627.1|refseq:NP_732628.1|refseq:NP_732629.1|refseq:NP_732630.1|refseq:NP_732631.1|refseq:NP_732632.1|refseq:NP_732633.1|refseq:NP_732634.1|refseq:NP_732635.1|refseq:NP_732636.1|flybase:FBgn0002781|refseq:NP_732623.2|interpro:IPR000210(BTB/POZ-like)|interpro:IPR007588(Zinc finger, FLYWCH-type)|interpro:IPR011333(BTB/POZ fold)|mint:Q86B87|refseq:NP_788698.1|refseq:NP_788699.1|refseq:NP_788700.1|refseq:NP_788701.1|refseq:NP_788702.1|refseq:NP_788703.1|refseq:NP_788704.1 pubmed:11350941(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+ilEJg0b+kjTjvxxkEZDNwSTMpg7227 rogid:b2OX/raroy6BMkaSC4EuYYprayM7227 intact-crc:5A3F176BCBF7F4FB|rigid:rdgoun4HjcelZs90s2uveVtuIu8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P50535 uniprotkb:O02193 intact:EBI-155450|uniprotkb:Q3ZAP1|uniprotkb:Q9VJ66|ensemblmetazoa:FBpp0080674|ensemblmetazoa:FBpp0309817 intact:EBI-138539|uniprotkb:Q9W463|uniprotkb:A8B845|uniprotkb:A8B850|uniprotkb:A8B854|uniprotkb:A8B859|uniprotkb:A8B879|uniprotkb:A8B889|uniprotkb:A8B895|uniprotkb:A8B8A1|uniprotkb:A8ILB7|uniprotkb:A8ILC1|uniprotkb:A8ILC8|uniprotkb:A8ILD1|uniprotkb:A8ILD6|uniprotkb:A8ILE1|uniprotkb:A8ILE5|ensemblmetazoa:FBpp0070794 psi-mi:msl1_drome(display_long)|uniprotkb:msl-1(gene name)|psi-mi:msl-1(display_short)|uniprotkb:CG10385(orf name) psi-mi:mof_drome(display_long)|uniprotkb:mof(gene name)|psi-mi:mof(display_short)|uniprotkb:Histone acetyl transferase MOF(gene name synonym)|uniprotkb:CG3025(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873678 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001286054.1|refseq:NP_476896.1|flybase:FBgn0005617|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0007549"(dosage compensation)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0016456"(X chromosome located dosage compensation complex, transcription activating)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0046536"(dosage compensation complex)|go:"GO:0072487"(MSL complex)|interpro:IPR026711|interpro:IPR029332|ensemblmetazoa:FBgn0005617(gene)|ensemblmetazoa:FBtr0081130(transcript)|ensemblmetazoa:FBtr0343118(transcript)|go:"GO:0000228"(nuclear chromosome)|dip:DIP-18144N go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000805"(X chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006281"(DNA repair)|go:"GO:0007549"(dosage compensation)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016456"(X chromosome located dosage compensation complex, transcription activating)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042393"(histone binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072487"(MSL complex)|go:"GO:2000873"(regulation of histone H4 acetylation involved in response to DNA damage stimulus)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037906|interpro:IPR040706|rcsb pdb:2BUD|ensemblmetazoa:FBgn0014340(gene)|ensemblmetazoa:FBtr0070829(transcript)|refseq:NP_511051.1|flybase:FBgn0014340|dip:DIP-46346N pubmed:10619853(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:fNvqBYYRB/IiH3KrLoXW3sTtpJc7227 rogid:YoHi/N+rxfKrb2CV6iRu+e0BEvs7227 intact-crc:4468700995E3700F|rigid:PFqrDsteESJBCTyp08twFy8Qtg0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KT87 uniprotkb:P16554 intact:EBI-870294|ensemblmetazoa:FBpp0304791 intact:EBI-429581|uniprotkb:Q8IPE9|uniprotkb:Q961A6|uniprotkb:Q9VLB8|uniprotkb:B8A413|uniprotkb:B8A419|ensemblmetazoa:FBpp0079420|ensemblmetazoa:FBpp0308609 psi-mi:q7kt87_drome(display_long)|uniprotkb:CG15268(gene name synonym)|uniprotkb:mol(gene name)|psi-mi:mol(display_short)|uniprotkb:"l(2)35Bb"(gene name synonym)|uniprotkb:"l(2)SH1330"(gene name synonym)|uniprotkb:"l(2)SH2 1330"(gene name synonym)|uniprotkb:"l(2)br23"(gene name synonym)|uniprotkb:"l(2)br3"(gene name synonym)|uniprotkb:l35Bb(gene name synonym)|uniprotkb:nip(gene name synonym)|uniprotkb:Dmel_CG4482(orf name)|uniprotkb:35Bb(gene name synonym)|uniprotkb:B1(gene name synonym)|uniprotkb:"BG:DS01219.1"(gene name synonym)|uniprotkb:Dmel\CG4482(gene name synonym)|uniprotkb:NIP(gene name synonym)|uniprotkb:br3(gene name synonym)|uniprotkb:Mol(gene name synonym)|uniprotkb:CG4482(orf name) psi-mi:numb_drome(display_long)|uniprotkb:CG3779(orf name)|uniprotkb:numb(gene name)|psi-mi:numb(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873682 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_723890.2|flybase:FBgn0086711|ensemblmetazoa:FBgn0086711(gene)|ensemblmetazoa:FBtr0332521(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045178"(basal part of cell)|interpro:IPR018469 refseq:NP_523523.2|refseq:NP_723460.1|flybase:FBgn0002973|refseq:NP_001260291.1|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051642"(centrosome localization)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|mint:P16554|go:"GO:0045178"(basal part of cell)|rcsb pdb:1DDM|rcsb pdb:2NMB|rcsb pdb:5YI7|rcsb pdb:5YI8|reactome:R-DME-5610780|reactome:R-DME-5632684|ensemblmetazoa:FBgn0002973(gene)|ensemblmetazoa:FBtr0079822(transcript)|ensemblmetazoa:FBtr0339526(transcript)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005112"(Notch binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008104"(protein localization)|go:"GO:0008347"(glial cell migration)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0045035"(sensory organ precursor cell division) pubmed:14670962(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:QaQ3pEl26h9wPAL+o4TAUBNwXfE7227 rogid:9FGhbcAA6k1LCDHPoLSXwEEVwzY7227 intact-crc:134D1CE79202A4B1|rigid:wkuyNS9PeWfYURtIuFICcKlPdgQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KND4 uniprotkb:Q7KND4 intact:EBI-868513|ensemblmetazoa:FBpp0291706 intact:EBI-868513|ensemblmetazoa:FBpp0291706 psi-mi:q7knd4_drome(display_long)|uniprotkb:mor(gene name)|psi-mi:mor(display_short)|uniprotkb:moira(gene name synonym)|uniprotkb:CG18740(orf name) psi-mi:q7knd4_drome(display_long)|uniprotkb:mor(gene name)|psi-mi:mor(display_short)|uniprotkb:moira(gene name synonym)|uniprotkb:CG18740(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873690 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0002783|ensemblmetazoa:FBgn0002783(gene)|ensemblmetazoa:FBtr0302550(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR032450 flybase:FBgn0002783|ensemblmetazoa:FBgn0002783(gene)|ensemblmetazoa:FBtr0302550(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR032450 pubmed:9891050(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NIID+nUemxYqyVHHGGKKXRz9nRo7227 rogid:NIID+nUemxYqyVHHGGKKXRz9nRo7227 intact-crc:675F7150FE4AFDA2|rigid:D1y5mr7jD3U8noNVDGe1O3a7HRs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24306 uniprotkb:Q86NX0 intact:EBI-456419|uniprotkb:A4V1Z9|uniprotkb:Q0E8E4|uniprotkb:Q8MRM5|uniprotkb:Q9VUX5|uniprotkb:A9UN33|ensemblmetazoa:FBpp0075254|ensemblmetazoa:FBpp0075255|ensemblmetazoa:FBpp0075256|ensemblmetazoa:FBpp0305793|ensemblmetazoa:FBpp0305794|ensemblmetazoa:FBpp0305795 intact:EBI-870300 psi-mi:diap1_drome(display_long)|uniprotkb:Diap1(gene name)|psi-mi:Diap1(display_short)|uniprotkb:Apoptosis 1 inhibitor(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase th(gene name synonym)|uniprotkb:Iap1(gene name synonym)|uniprotkb:Inhibitor of apoptosis 1(gene name synonym)|uniprotkb:Protein thread(gene name synonym)|uniprotkb:th(gene name synonym)|uniprotkb:CG12284(orf name)|uniprotkb:RING-type E3 ubiquitin transferase Diap1(gene name synonym) psi-mi:q86nx0_drome(display_long)|uniprotkb:morgue(gene name)|psi-mi:morgue(display_short)|uniprotkb:CG15437(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873694 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524101.2|refseq:NP_730097.1|refseq:NP_730098.1|flybase:FBgn0260635|refseq:NP_001261916.1|refseq:NP_001261917.1|refseq:NP_001261918.1|go:"GO:0006915"(apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0022416"(chaeta development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0045116"(protein neddylation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|ensemblmetazoa:FBgn0260635(gene)|ensemblmetazoa:FBtr0075499(transcript)|ensemblmetazoa:FBtr0075500(transcript)|ensemblmetazoa:FBtr0075501(transcript)|ensemblmetazoa:FBtr0333617(transcript)|ensemblmetazoa:FBtr0333618(transcript)|ensemblmetazoa:FBtr0333619(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|mint:Q24306|rcsb pdb:1JD4|rcsb pdb:1JD5|rcsb pdb:1JD6|rcsb pdb:1Q4Q|rcsb pdb:1SDZ|rcsb pdb:1SE0|rcsb pdb:3SIP|rcsb pdb:3SIQ|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-3769402|reactome:R-DME-390150|reactome:R-DME-5675482|reactome:R-DME-8948747|reactome:R-DME-8948751 flybase:FBgn0027609|go:"GO:0005634"(nucleus)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1901694"(positive regulation of compound eye retinal cell apoptotic process)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR036047 pubmed:12021772(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:loBQ//cKQ1NYhq3gnIKwRBn5vZg7227 rogid:HLJhoyPe9e85H35xvgmdUKKvyxA7227 intact-crc:04FD7C39A96D3CCB|rigid:J/WBflSKE80k+lTWd7tvPKq4V0k false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O77430 uniprotkb:Q86NX0 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 intact:EBI-870300 psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:q86nx0_drome(display_long)|uniprotkb:morgue(gene name)|psi-mi:morgue(display_short)|uniprotkb:CG15437(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873698 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 flybase:FBgn0027609|go:"GO:0005634"(nucleus)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1901694"(positive regulation of compound eye retinal cell apoptotic process)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR036047 pubmed:12021772(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 rogid:HLJhoyPe9e85H35xvgmdUKKvyxA7227 intact-crc:D49463AF0DFC701F|rigid:kUQrtY03c3fazYCzT0VBmPzOcLA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40417 uniprotkb:Q7KIF8 intact:EBI-867790|uniprotkb:A0A021WW06|uniprotkb:Q7PL59|uniprotkb:Q9W5M2|uniprotkb:A8Y4W1|uniprotkb:A8Y4W2|uniprotkb:Q9W5M3|ensemblmetazoa:FBpp0112423|ensemblmetazoa:FBpp0112425|ensemblmetazoa:FBpp0112426|ensemblmetazoa:FBpp0311493 intact:EBI-868910 psi-mi:erka_drome(display_long)|uniprotkb:Extracellular-regulated kinase A(gene name synonym)|uniprotkb:Protein rolled(gene name synonym)|uniprotkb:rl(gene name)|psi-mi:rl(display_short)|uniprotkb:ERKa(gene name synonym)|uniprotkb:CG12559(orf name)|uniprotkb:MAPK(gene name synonym) psi-mi:q7kif8_drome(display_long)|uniprotkb:msk(gene name)|psi-mi:msk(display_short)|uniprotkb:CG7935(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873702 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001015121.3|refseq:NP_001104348.2|refseq:NP_001287635.1|refseq:NP_001015122.1|refseq:NP_001015123.1|refseq:NP_001104349.1|flybase:FBgn0003256|dip:DIP-17266N|ensemblmetazoa:FBgn0003256(gene)|ensemblmetazoa:FBtr0113700(transcript)|ensemblmetazoa:FBtr0113702(transcript)|ensemblmetazoa:FBtr0113703(transcript)|ensemblmetazoa:FBtr0345337(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007362"(terminal region determination)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000826"(regulation of heart morphogenesis)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P40417|reactome:R-DME-110056|reactome:R-DME-112409|reactome:R-DME-112411|reactome:R-DME-1295596|reactome:R-DME-162658|reactome:R-DME-170968|reactome:R-DME-198753|reactome:R-DME-202670|reactome:R-DME-2029482|reactome:R-DME-2559580|reactome:R-DME-2559582|reactome:R-DME-2559585|reactome:R-DME-2871796|reactome:R-DME-3371453|reactome:R-DME-375165|reactome:R-DME-437239|reactome:R-DME-445144|reactome:R-DME-450341|reactome:R-DME-456926|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5654733|reactome:R-DME-5663213|reactome:R-DME-5673001|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5687128|reactome:R-DME-6798695|reactome:R-DME-74749|reactome:R-DME-881907|reactome:R-DME-9634635|reactome:R-DME-9634638 flybase:FBgn0026252|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0015030"(Cajal body)|go:"GO:0016203"(muscle attachment)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0030576"(Cajal body organization)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035311"(wing cell fate specification)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045465"(R8 cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048749"(compound eye development)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold) pubmed:11262240(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:m7w7KhuZSyx3t+dR2TKtvx/vRtA7227 rogid:LyYWvxv5lrIKAyUcBdCYuv0gajw7227 intact-crc:DDEDB0465166F405|rigid:a1UcXFVa2PV+ffp0+Lj/8s8vBEs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P50536 uniprotkb:P50535 intact:EBI-273810|uniprotkb:Q8IQ74|uniprotkb:Q9VS18|uniprotkb:A8BP72|uniprotkb:A8BP74|uniprotkb:A8BP87|uniprotkb:A8BP92|uniprotkb:A8IL14|uniprotkb:A8IL17|uniprotkb:A8IL22|uniprotkb:A8IL25|uniprotkb:A8IL30|uniprotkb:A8IL33|uniprotkb:A8IL37|uniprotkb:A8IL41|uniprotkb:A8IL46|intact:EBI-273823|ensemblmetazoa:FBpp0076635 intact:EBI-155450|uniprotkb:Q3ZAP1|uniprotkb:Q9VJ66|ensemblmetazoa:FBpp0080674|ensemblmetazoa:FBpp0309817 psi-mi:msl3_drome(display_long)|uniprotkb:msl-3(gene name)|psi-mi:msl-3(display_short)|uniprotkb:CG8631(orf name) psi-mi:msl1_drome(display_long)|uniprotkb:msl-1(gene name)|psi-mi:msl-1(display_short)|uniprotkb:CG10385(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873706 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523951.1|flybase:FBgn0002775|dip:DIP-23734N|ensemblmetazoa:FBgn0002775(gene)|ensemblmetazoa:FBtr0076926(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000805"(X chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006342"|go:"GO:0007549"(dosage compensation)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010369"(chromocenter)|go:"GO:0016456"(X chromosome located dosage compensation complex, transcription activating)|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0072487"(MSL complex)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR026541|rcsb pdb:3M9Q refseq:NP_001286054.1|refseq:NP_476896.1|flybase:FBgn0005617|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0007549"(dosage compensation)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0016456"(X chromosome located dosage compensation complex, transcription activating)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0046536"(dosage compensation complex)|go:"GO:0072487"(MSL complex)|interpro:IPR026711|interpro:IPR029332|ensemblmetazoa:FBgn0005617(gene)|ensemblmetazoa:FBtr0081130(transcript)|ensemblmetazoa:FBtr0343118(transcript)|go:"GO:0000228"(nuclear chromosome)|dip:DIP-18144N pubmed:10619853(see-also)|pubmed:9736618(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:U5/4FvrDTGTDRFkXxFXakNRLBdQ7227 rogid:fNvqBYYRB/IiH3KrLoXW3sTtpJc7227 intact-crc:7B843AF99F1565AD|rigid:dFiI8D6cD1DkUxCID4Z1B7P9+Ec false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P50534 uniprotkb:P50535 intact:EBI-175165|uniprotkb:Q9VQR1|ensemblmetazoa:FBpp0077259|ensemblmetazoa:FBpp0077260 intact:EBI-155450|uniprotkb:Q3ZAP1|uniprotkb:Q9VJ66|ensemblmetazoa:FBpp0080674|ensemblmetazoa:FBpp0309817 psi-mi:msl2_drome(display_long)|uniprotkb:msl-2(gene name)|psi-mi:msl-2(display_short)|uniprotkb:Protein male-specific lethal-2(gene name synonym)|uniprotkb:CG3241(orf name)|uniprotkb:E3 ubiquitin-protein transferase msl-2(gene name synonym) psi-mi:msl1_drome(display_long)|uniprotkb:msl-1(gene name)|psi-mi:msl-1(display_short)|uniprotkb:CG10385(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873710 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523467.1|refseq:NP_722907.1|flybase:FBgn0005616|ensemblmetazoa:FBgn0005616(gene)|ensemblmetazoa:FBtr0077570(transcript)|ensemblmetazoa:FBtr0077571(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000805"(X chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0007549"(dosage compensation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0016456"(X chromosome located dosage compensation complex, transcription activating)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0046536"(dosage compensation complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0072487"(MSL complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032043|interpro:IPR032049|interpro:IPR033467|interpro:IPR037922|rcsb pdb:2LUA|rcsb pdb:4RKG|rcsb pdb:4RKH refseq:NP_001286054.1|refseq:NP_476896.1|flybase:FBgn0005617|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0007549"(dosage compensation)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0016456"(X chromosome located dosage compensation complex, transcription activating)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0046536"(dosage compensation complex)|go:"GO:0072487"(MSL complex)|interpro:IPR026711|interpro:IPR029332|ensemblmetazoa:FBgn0005617(gene)|ensemblmetazoa:FBtr0081130(transcript)|ensemblmetazoa:FBtr0343118(transcript)|go:"GO:0000228"(nuclear chromosome)|dip:DIP-18144N pubmed:9736618(see-also)|pubmed:10619853(see-also)|pubmed:9409833(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:0+L5V487Qs0hWAaeAnPVeUfDT1I7227 rogid:fNvqBYYRB/IiH3KrLoXW3sTtpJc7227 intact-crc:37B756E41EF73440|rigid:U9PVAyML6Oa8m8gwZb2JOK/JPik false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9UAC5 uniprotkb:Q7KV88 intact:EBI-868447 intact:EBI-868359|ensemblmetazoa:FBpp0089311|ensemblmetazoa:FBpp0089312 psi-mi:q9uac5_drome(display_long)|uniprotkb:Traf4(gene name)|psi-mi:Traf4(display_short)|uniprotkb:traf1(gene name synonym)|uniprotkb:CG3048(orf name)|uniprotkb:Traf1(gene name synonym) psi-mi:q7kv88_drome(display_long)|uniprotkb:CG16973-RD(gene name synonym)|uniprotkb:CG16973(orf name)|uniprotkb:msn(gene name)|psi-mi:msn(display_short)|uniprotkb:6286(gene name synonym)|uniprotkb:DMSN(gene name synonym)|uniprotkb:Dmel\CG16973(gene name synonym)|uniprotkb:HGK(gene name synonym)|uniprotkb:JNKKKK(gene name synonym)|uniprotkb:MESR5(gene name synonym)|uniprotkb:MSN(gene name synonym)|uniprotkb:Msn(gene name synonym)|uniprotkb:NIK(gene name synonym)|uniprotkb:Nik(gene name synonym)|uniprotkb:"l(3)03349"(gene name synonym)|uniprotkb:"l(3)06946"(gene name synonym)|uniprotkb:"l(3)6286"(gene name synonym)|uniprotkb:"l(3)j1E2"(gene name synonym)|uniprotkb:msm(gene name synonym)|uniprotkb:Dmel_CG16973(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873714 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0026319|go:"GO:0001654"(eye development)|go:"GO:0003384"(apical constriction involved in gastrulation)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|go:"GO:0034332"(adherens junction organization) refseq:NP_995972.1|refseq:NP_995973.1|flybase:FBgn0010909|ensemblmetazoa:FBtr0072958(transcript)|ensemblmetazoa:FBtr0072959(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001748"(insect visual primordium development)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007097"(nuclear migration)|go:"GO:0007254"(JNK cascade)|go:"GO:0007391"(dorsal closure)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009611"(response to wounding)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042656"(JUN kinase kinase kinase kinase activity)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR021160|ensemblmetazoa:FBgn0010909(gene) pubmed:10021364(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:I+bBjRvDZ/MnoA5YyVxty92NBzE7227 rogid:rcJvSCSw3DtAy5Tu69AYlOm0O6c7227 intact-crc:D9028F8BFAEBDCA8|rigid:b9oGm6Pl9pTXaOF8bL2Ek+Ia/Cg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q3YNE8 uniprotkb:Q95TZ9 intact:EBI-868084 intact:EBI-499902|ensemblmetazoa:FBpp0290694 psi-mi:q3yne8_drome(display_long)|uniprotkb:tacc(gene name)|psi-mi:tacc(display_short)|uniprotkb:CG9765(orf name) psi-mi:q95tz9_drome(display_long)|uniprotkb:msps(gene name)|psi-mi:msps(display_short)|uniprotkb:CG5000(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873718 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0026620|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007279"(pole cell formation)|go:"GO:0007344"(pronuclear fusion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008104"(protein localization)|go:"GO:0035046"(pronuclear migration) flybase:FBgn0027948|ensemblmetazoa:FBgn0027948(gene)|ensemblmetazoa:FBtr0301479(transcript)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085 pubmed:11433295(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:PO4DpvSnzmXnfZp8sxH2Ohwr4VQ7227 rogid:Ud5YVGI3pgIf6hA90ozebVARAww7227 intact-crc:644B4F485D5E3A18|rigid:SNKKvwDzbTjYcHnKNGVhfNfDXmE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20480 uniprotkb:Q95TZ9 intact:EBI-84482|uniprotkb:Q9VAG8|ensemblmetazoa:FBpp0084900|ensemblmetazoa:FBpp0311231 intact:EBI-499902|ensemblmetazoa:FBpp0290694 psi-mi:ncd_drome(display_long)|uniprotkb:ncd(gene name)|psi-mi:ncd(display_short)|uniprotkb:"CA(ND)"(gene name synonym)|uniprotkb:CG7831(orf name) psi-mi:q95tz9_drome(display_long)|uniprotkb:msps(gene name)|psi-mi:msps(display_short)|uniprotkb:CG5000(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873722 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0031534"(minus-end directed microtubule sliding)|go:"GO:0032837"(distributive segregation)|ensemblmetazoa:FBtr0344976(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0072687"(meiotic spindle)|ensemblmetazoa:FBgn0002924(gene)|ensemblmetazoa:FBtr0085534(transcript)|rcsb pdb:3U06|rcsb pdb:5HLE|rcsb pdb:5HNW|rcsb pdb:5HNX|rcsb pdb:5HNY|rcsb pdb:5HNZ|rcsb pdb:5W3D|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:1CZ7|rcsb pdb:1N6M|rcsb pdb:1OZX|rcsb pdb:1SYJ|rcsb pdb:1SYP|rcsb pdb:1SZ4|rcsb pdb:1SZ5|rcsb pdb:2NCD|rcsb pdb:3L1C|refseq:NP_476651.1|flybase:FBgn0002924|refseq:NP_001287592.1|dip:DIP-21302N flybase:FBgn0027948|ensemblmetazoa:FBgn0027948(gene)|ensemblmetazoa:FBtr0301479(transcript)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085 pubmed:11433295(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8sydvdYOvP3j1aqufTIH/rvDyJw7227 rogid:Ud5YVGI3pgIf6hA90ozebVARAww7227 intact-crc:BB0F6BECD86792C2|rigid:XCE6ydmvky74g2rv2bHGp0hnI4k false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P22812 uniprotkb:Q7K105 intact:EBI-93181|uniprotkb:Q9VN15|uniprotkb:B7Z0I9|uniprotkb:E8NH30|ensemblmetazoa:FBpp0291542 intact:EBI-129988|ensemblmetazoa:FBpp0087679|ensemblmetazoa:FBpp0305215|ensemblmetazoa:FBpp0311274 psi-mi:tube_drome(display_long)|uniprotkb:CG10520(orf name)|uniprotkb:tub(gene name)|psi-mi:tub(display_short)|uniprotkb:tube(gene name synonym) psi-mi:q7k105_drome(display_long)|uniprotkb:Myd88(gene name)|psi-mi:Myd88(display_short)|uniprotkb:DMMYD88(gene name synonym)|uniprotkb:DmMyD88(gene name synonym)|uniprotkb:DmMyd88(gene name synonym)|uniprotkb:Dmel\CG2078(gene name synonym)|uniprotkb:"EP(2)2535"(gene name synonym)|uniprotkb:Kra(gene name synonym)|uniprotkb:LD20892(gene name synonym)|uniprotkb:MYD88(gene name synonym)|uniprotkb:MyD88(gene name synonym)|uniprotkb:Myd88F(gene name synonym)|uniprotkb:dMYd88(gene name synonym)|uniprotkb:dMyD88(gene name synonym)|uniprotkb:dMyd88(gene name synonym)|uniprotkb:kra(gene name synonym)|uniprotkb:myd88(gene name synonym)|uniprotkb:CG2078(orf name)|uniprotkb:Dmel_CG2078(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873726 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189164.1|flybase:FBgn0003882|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR029397|rcsb pdb:1D2Z|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874|go:"GO:0045087"(innate immune response)|ensemblmetazoa:FBgn0003882(gene)|ensemblmetazoa:FBtr0302338(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009620"(response to fungus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|dip:DIP-27623N refseq:NP_610479.1|flybase:FBgn0033402|refseq:NP_001286246.1|ensemblmetazoa:FBgn0033402(gene)|ensemblmetazoa:FBtr0088598(transcript)|ensemblmetazoa:FBtr0333000(transcript)|ensemblmetazoa:FBtr0345024(transcript)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002347"(response to tumor cell)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0005121"(Toll binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0070976"(TIR domain binding)|interpro:IPR011029(DEATH-like)|interpro:IPR017281(Myeloid differentiation primary response protein MyD88)|interpro:IPR035897|reactome:R-DME-1810476|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874|reactome:R-DME-3134963|interpro:IPR000157(Toll-Interleukin receptor)|refseq:NP_001260821.1 pubmed:14685264(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:v00LZV72cvvYVI5cCthONXIlmrs7227 rogid:ylgI2zl+aLG3S8D2ER2DrTRUpI47227 intact-crc:0A3A1CA04EBC1340|rigid:wldgN2majJxREvftSUEmhwg7UTg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O44386 uniprotkb:P11584 intact:EBI-280866|uniprotkb:O44387|uniprotkb:O46186|uniprotkb:Q58CK3|uniprotkb:Q6AWK3|uniprotkb:Q9V7A3|ensemblmetazoa:FBpp0086501 intact:EBI-169569|uniprotkb:Q8MYX9|uniprotkb:Q9W3L2|ensemblmetazoa:FBpp0071061|ensemblmetazoa:FBpp0309122|ensemblmetazoa:FBpp0309123 psi-mi:ita3_drome(display_long)|uniprotkb:Position-specific antigen subunit alpha-3(gene name synonym)|uniprotkb:Protein volado(gene name synonym)|uniprotkb:scb(gene name)|psi-mi:scb(display_short)|uniprotkb:Vol(gene name synonym)|uniprotkb:CG8095(orf name)|uniprotkb:alphaPS3(gene name synonym) psi-mi:itbx_drome(display_long)|uniprotkb:mys(gene name)|psi-mi:mys(display_short)|uniprotkb:"l(1)mys"(gene name synonym)|uniprotkb:olfC(gene name synonym)|uniprotkb:CG1560(orf name)|uniprotkb:Position-specific antigen beta subunit(gene name synonym)|uniprotkb:Protein myospheroid(gene name synonym)|uniprotkb:Protein olfactory C(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873730 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523750.2|refseq:NP_725445.1|flybase:FBgn0286785|ensemblmetazoa:FBgn0286785(gene)|ensemblmetazoa:FBtr0087369(transcript)|go:"GO:0001555"(oocyte growth)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007391"(dorsal closure)|go:"GO:0007411"(axon guidance)|go:"GO:0007431"(salivary gland development)|go:"GO:0007494"(midgut development)|go:"GO:0007508"(larval heart development)|go:"GO:0007613"(memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008305"(integrin complex)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035001"(dorsal trunk growth, open tracheal system)|go:"GO:0042060"(wound healing)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048149"(behavioral response to ethanol)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|reactome:R-DME-216083|reactome:R-DME-3000157|reactome:R-DME-3000170|reactome:R-DME-446107 ensemblmetazoa:FBgn0004657(gene)|ensemblmetazoa:FBtr0071105(transcript)|ensemblmetazoa:FBtr0340136(transcript)|ensemblmetazoa:FBtr0340137(transcript)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007377"(germ-band extension)|go:"GO:0007391"(dorsal closure)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007431"(salivary gland development)|go:"GO:0007494"(midgut development)|go:"GO:0007508"(larval heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0007629"(flight behavior)|go:"GO:0008305"(integrin complex)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016340"(calcium-dependent cell-matrix adhesion)|go:"GO:0021551"(central nervous system morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031252"(cell leading edge)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035001"(dorsal trunk growth, open tracheal system)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043034"(costamere)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0090129"(positive regulation of synapse maturation)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR032695|interpro:IPR036349|interpro:IPR036465|reactome:R-DME-1566977|reactome:R-DME-198933|reactome:R-DME-202733|reactome:R-DME-2129379|reactome:R-DME-216083|reactome:R-DME-3000157|reactome:R-DME-3000170|reactome:R-DME-3000178|reactome:R-DME-446107|reactome:R-DME-446343|reactome:R-DME-6798695|reactome:R-DME-9013149|reactome:R-DME-9013404|go:"GO:0016477"(cell migration)|refseq:NP_001284998.1|refseq:NP_001284999.1|refseq:NP_524793.2|flybase:FBgn0004657 pubmed:9409675(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:E3o+8S9ICJTAHZ5gA6M3hlwcsAk7227 rogid:CmFidny9jo+Zvpte2IK2BFX60tQ7227 intact-crc:45744B22966E2D43|rigid:dvr7z4x9yp6bKu3TpOQ3B1aAMqE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09615 uniprotkb:P07207 intact:EBI-98242|uniprotkb:Q27768|uniprotkb:Q27769|uniprotkb:Q8IPI1|uniprotkb:Q8MQP9|uniprotkb:Q9VM27|ensemblmetazoa:FBpp0079060 intact:EBI-103438|uniprotkb:O97458|uniprotkb:P04154|uniprotkb:Q9W4T8|ensemblmetazoa:FBpp0070483|ensemblmetazoa:FBpp0293201 psi-mi:wntg_drome(display_long)|uniprotkb:Protein Wnt-1(gene name synonym)|uniprotkb:Protein int-1(gene name synonym)|uniprotkb:CG4889(orf name)|uniprotkb:wg(gene name)|psi-mi:wg(display_short)|uniprotkb:dWnt-1(gene name synonym)|uniprotkb:dInt-1(gene name synonym) psi-mi:notch_drome(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:CG3936(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873734 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523502.1|ensemblmetazoa:FBgn0284084(gene)|ensemblmetazoa:FBtr0079432(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007398"(ectoderm development)|go:"GO:0007418"(ventral midline development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007523"(larval visceral muscle development)|go:"GO:0007616"(long-term memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014019"(neuroblast development)|go:"GO:0016015"(morphogen activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0061328"(posterior Malpighian tubule development)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061332"(Malpighian tubule bud morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR043158|reactome:R-DME-201681|reactome:R-DME-209387|reactome:R-DME-209440|reactome:R-DME-209472|reactome:R-DME-3238698|reactome:R-DME-4086400|reactome:R-DME-4641262|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032876"(negative regulation of DNA endoreduplication)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035217"(labial disc development)|go:"GO:0035220"(wing disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035263"(genital disc sexually dimorphic development)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035311"(wing cell fate specification)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043195"(terminal bouton)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048332"(mesoderm morphogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048728"(proboscis development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050808"(synapse organization)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0060061"(Spemann organizer formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060914"(heart formation)|go:"GO:0061316"(canonical Wnt signaling pathway involved in heart development)|go:"GO:0045572"(positive regulation of imaginal disc growth)|flybase:FBgn0284084|dip:DIP-21777N refseq:NP_476859.2|flybase:FBgn0004647|ensemblmetazoa:FBgn0004647(gene)|ensemblmetazoa:FBtr0070507(transcript)|ensemblmetazoa:FBtr0304659(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002213"(defense response to insect)|go:"GO:0003682"(chromatin binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007391"(dorsal closure)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009608"(response to symbiont)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0022416"(chaeta development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0007498"(mesoderm development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0007616"(long-term memory)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0040008"(regulation of growth)|go:"GO:0042686"(regulation of cardioblast cell fate specification)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045316"(negative regulation of compound eye photoreceptor development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048627"(myoblast development)|go:"GO:0048664"(neuron fate determination)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050699"(WW domain binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0060289"(compartment boundary maintenance)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990433"(CSL-Notch-Mastermind transcription factor complex)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1OT8|rcsb pdb:2JMF|refseq:NP_001245510.1|dip:DIP-5N pubmed:7954794(see-also)|pubmed:8575321(see-also)|pubmed:7848873(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ioGPXpHjZchgMT2/PR2ivC4Jo+s7227 rogid:T1iHJGMHXkhxbFRybmSDlizN7oQ7227 intact-crc:0E3393AAB4A5902F|rigid:sGM93wh82+1dE4dyplyg07lAEB4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P28159 uniprotkb:P07207 intact:EBI-92180|uniprotkb:Q3S1M8|uniprotkb:Q9TVK8|uniprotkb:Q9TVY7|uniprotkb:Q9TW34|uniprotkb:Q9U8F9|uniprotkb:Q9V446|ensemblmetazoa:FBpp0080261|ensemblmetazoa:FBpp0312201 intact:EBI-103438|uniprotkb:O97458|uniprotkb:P04154|uniprotkb:Q9W4T8|ensemblmetazoa:FBpp0070483|ensemblmetazoa:FBpp0293201 psi-mi:suh_drome(display_long)|uniprotkb:"Su(H)"(gene name)|psi-mi:"Su(H)"(display_short)|uniprotkb:dRBP-JK(gene name synonym)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym)|uniprotkb:CG3497(orf name) psi-mi:notch_drome(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:CG3936(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873738 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001285948.1|refseq:NP_476868.1|flybase:FBgn0004837|ensemblmetazoa:FBgn0004837(gene)|ensemblmetazoa:FBtr0080700(transcript)|ensemblmetazoa:FBtr0346621(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007616"(long-term memory)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042683"(negative regulation of compound eye cone cell fate specification)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1990433"(CSL-Notch-Mastermind transcription factor complex)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|rcsb pdb:5E24|dip:DIP-177N refseq:NP_476859.2|flybase:FBgn0004647|ensemblmetazoa:FBgn0004647(gene)|ensemblmetazoa:FBtr0070507(transcript)|ensemblmetazoa:FBtr0304659(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002213"(defense response to insect)|go:"GO:0003682"(chromatin binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007391"(dorsal closure)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009608"(response to symbiont)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0022416"(chaeta development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0007498"(mesoderm development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0007616"(long-term memory)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0040008"(regulation of growth)|go:"GO:0042686"(regulation of cardioblast cell fate specification)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045316"(negative regulation of compound eye photoreceptor development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048627"(myoblast development)|go:"GO:0048664"(neuron fate determination)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050699"(WW domain binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0060289"(compartment boundary maintenance)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990433"(CSL-Notch-Mastermind transcription factor complex)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1OT8|rcsb pdb:2JMF|refseq:NP_001245510.1|dip:DIP-5N pubmed:7590238(see-also)|pubmed:8787746(see-also)|pubmed:9651681(see-also)|pubmed:15123610(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:3NFMvvrfh1WC+s9QwiDW5BCUr5I7227 rogid:T1iHJGMHXkhxbFRybmSDlizN7oQ7227 intact-crc:1E6156339BA31594|rigid:qbq3TiqsqUPg/wmwJIwTNxKEMoE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18168 uniprotkb:P07207 intact:EBI-668028|uniprotkb:Q9VB65|intact:EBI-3409750|ensemblmetazoa:FBpp0084498 intact:EBI-103438|uniprotkb:O97458|uniprotkb:P04154|uniprotkb:Q9W4T8|ensemblmetazoa:FBpp0070483|ensemblmetazoa:FBpp0293201 psi-mi:serr_drome(display_long)|uniprotkb:Protein beaded(gene name synonym)|uniprotkb:Ser(gene name)|psi-mi:Ser(display_short)|uniprotkb:Bd(gene name synonym)|uniprotkb:CG6127(orf name) psi-mi:notch_drome(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:CG3936(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873742 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524527.3|flybase:FBgn0004197|refseq:NP_001287558.1|ensemblmetazoa:FBgn0004197(gene)|ensemblmetazoa:FBtr0085128(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007423"(sensory organ development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007436"(larval salivary gland morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0030673"(axolemma)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0045179"(apical cortex)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048749"(compound eye development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026219|mint:P18168 refseq:NP_476859.2|flybase:FBgn0004647|ensemblmetazoa:FBgn0004647(gene)|ensemblmetazoa:FBtr0070507(transcript)|ensemblmetazoa:FBtr0304659(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002213"(defense response to insect)|go:"GO:0003682"(chromatin binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007391"(dorsal closure)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009608"(response to symbiont)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0022416"(chaeta development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0007498"(mesoderm development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0007616"(long-term memory)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0040008"(regulation of growth)|go:"GO:0042686"(regulation of cardioblast cell fate specification)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045316"(negative regulation of compound eye photoreceptor development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048627"(myoblast development)|go:"GO:0048664"(neuron fate determination)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050699"(WW domain binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0060289"(compartment boundary maintenance)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990433"(CSL-Notch-Mastermind transcription factor complex)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1OT8|rcsb pdb:2JMF|refseq:NP_001245510.1|dip:DIP-5N pubmed:7720588(see-also)|pubmed:8483919(see-also)|pubmed:10504334(see-also)|pubmed:10862754(see-also)|pubmed:1657403(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:67XB9KE9JvKFJhBP11iDczeQH1I7227 rogid:T1iHJGMHXkhxbFRybmSDlizN7oQ7227 intact-crc:C98C69CC4CCC47BF|rigid:eN3Vb5uh+yMTKtO+HTt8ufzx+GE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O02194 uniprotkb:P07207 intact:EBI-255741|uniprotkb:O02395|uniprotkb:O76802|uniprotkb:O96340|uniprotkb:Q9TY80|uniprotkb:Q9V3L9|uniprotkb:Q9V3S1|ensemblmetazoa:FBpp0077850|ensemblmetazoa:FBpp0305666 intact:EBI-103438|uniprotkb:O97458|uniprotkb:P04154|uniprotkb:Q9W4T8|ensemblmetazoa:FBpp0070483|ensemblmetazoa:FBpp0293201 psi-mi:psn_drome(display_long)|uniprotkb:Psn(gene name)|psi-mi:Psn(display_short)|uniprotkb:PS(gene name synonym)|uniprotkb:CG18803(orf name)|uniprotkb:dPS(gene name synonym) psi-mi:notch_drome(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:CG3936(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873746 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0284421|refseq:NP_524184.1|refseq:NP_730535.1|refseq:NP_001262110.1|refseq:NP_001262111.1|dip:DIP-1139N|ensemblmetazoa:FBgn0284421(gene)|ensemblmetazoa:FBtr0078192(transcript)|ensemblmetazoa:FBtr0333479(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006508"(proteolysis)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0009986"(cell surface)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030018"(Z disc)|go:"GO:0030426"(growth cone)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035333"(Notch receptor processing, ligand-dependent)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0070765"(gamma-secretase complex)|interpro:IPR001108(Peptidase A22A, presenilin)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR042524|reactome:R-DME-1251985|reactome:R-DME-3928665|reactome:R-DME-6798695 refseq:NP_476859.2|flybase:FBgn0004647|ensemblmetazoa:FBgn0004647(gene)|ensemblmetazoa:FBtr0070507(transcript)|ensemblmetazoa:FBtr0304659(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002213"(defense response to insect)|go:"GO:0003682"(chromatin binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007391"(dorsal closure)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009608"(response to symbiont)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0022416"(chaeta development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0007498"(mesoderm development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0007616"(long-term memory)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0040008"(regulation of growth)|go:"GO:0042686"(regulation of cardioblast cell fate specification)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045316"(negative regulation of compound eye photoreceptor development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048627"(myoblast development)|go:"GO:0048664"(neuron fate determination)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050699"(WW domain binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0060289"(compartment boundary maintenance)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990433"(CSL-Notch-Mastermind transcription factor complex)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1OT8|rcsb pdb:2JMF|refseq:NP_001245510.1|dip:DIP-5N pubmed:10206646(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:UZooKoj+G0I4jZIcHgX+55Nlw887227 rogid:T1iHJGMHXkhxbFRybmSDlizN7oQ7227 intact-crc:2A6024F2C528543D|rigid:iTSxH63FUOji+MNIW38v6ct2ClM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P04755 uniprotkb:O18394 intact:EBI-85096|uniprotkb:Q9VZC3 intact:EBI-870315 psi-mi:ach3_drome(display_long)|uniprotkb:nAChRbeta1(gene name)|psi-mi:nAChRbeta1(display_short)|uniprotkb:Acr64B(gene name synonym)|uniprotkb:AcrD(gene name synonym)|uniprotkb:Nicotinic acetylcholine receptor beta 1(gene name synonym)|uniprotkb:ard(gene name synonym)|uniprotkb:nAcRbeta-64B(gene name synonym)|uniprotkb:CG11348(orf name) psi-mi:o18394_drome(display_long)|uniprotkb:nAChRalpha3(gene name)|psi-mi:nAChRalpha3(display_short)|uniprotkb:nACRalpha-7E(gene name synonym)|uniprotkb:nAcR-alpha-7E(gene name synonym)|uniprotkb:nAcRalpha-7E(gene name synonym)|uniprotkb:CG2302(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873750 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|reactome:R-DME-629587|reactome:R-DME-629594|interpro:IPR036734|refseq:NP_523927.2|flybase:FBgn0000038 flybase:FBgn0015519|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006812"(cation transport)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734 pubmed:11024458(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:0LHCK05JnM5JMssYjiFZuv6x3rk7227 rogid:0rNZE1mK4oW93DUVboSWOfi6tXI7227 intact-crc:4D7695CC6B3EF677|rigid:7jYL+Mz60MbzG42Ho2cuJF3jWIQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16554 uniprotkb:Q7KT38 intact:EBI-429581|uniprotkb:Q8IPE9|uniprotkb:Q961A6|uniprotkb:Q9VLB8|uniprotkb:B8A413|uniprotkb:B8A419|ensemblmetazoa:FBpp0079420|ensemblmetazoa:FBpp0308609 intact:EBI-870332|ensemblmetazoa:FBpp0089380 psi-mi:numb_drome(display_long)|uniprotkb:CG3779(orf name)|uniprotkb:numb(gene name)|psi-mi:numb(display_short) psi-mi:q7kt38_drome(display_long)|uniprotkb:Nak(gene name)|psi-mi:Nak(display_short)|uniprotkb:Dmel\CG10637(gene name synonym)|uniprotkb:nak(gene name synonym)|uniprotkb:Dmel_CG10637(orf name)|uniprotkb:CG10637(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873754 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523523.2|refseq:NP_723460.1|flybase:FBgn0002973|refseq:NP_001260291.1|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051642"(centrosome localization)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|mint:P16554|go:"GO:0045178"(basal part of cell)|rcsb pdb:1DDM|rcsb pdb:2NMB|rcsb pdb:5YI7|rcsb pdb:5YI8|reactome:R-DME-5610780|reactome:R-DME-5632684|ensemblmetazoa:FBgn0002973(gene)|ensemblmetazoa:FBtr0079822(transcript)|ensemblmetazoa:FBtr0339526(transcript)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005112"(Notch binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008104"(protein localization)|go:"GO:0008347"(glial cell migration)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0045035"(sensory organ precursor cell division) refseq:NP_995725.1|flybase:FBgn0015772|ensemblmetazoa:FBgn0015772(gene)|ensemblmetazoa:FBtr0081189(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051425"(PTB domain binding)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like) pubmed:9418906(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:9FGhbcAA6k1LCDHPoLSXwEEVwzY7227 rogid:NNztzyI+8U6bf0byXN7XZMqocOI7227 intact-crc:5A5EA7E7092FFABB|rigid:PujbKVbbD1GjNa3EkuEYC1Y1oJc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24306 uniprotkb:Q9XYF4 intact:EBI-456419|uniprotkb:A4V1Z9|uniprotkb:Q0E8E4|uniprotkb:Q8MRM5|uniprotkb:Q9VUX5|uniprotkb:A9UN33|ensemblmetazoa:FBpp0075254|ensemblmetazoa:FBpp0075255|ensemblmetazoa:FBpp0075256|ensemblmetazoa:FBpp0305793|ensemblmetazoa:FBpp0305794|ensemblmetazoa:FBpp0305795 intact:EBI-108311|ensemblmetazoa:FBpp0076076 psi-mi:diap1_drome(display_long)|uniprotkb:Diap1(gene name)|psi-mi:Diap1(display_short)|uniprotkb:Apoptosis 1 inhibitor(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase th(gene name synonym)|uniprotkb:Iap1(gene name synonym)|uniprotkb:Inhibitor of apoptosis 1(gene name synonym)|uniprotkb:Protein thread(gene name synonym)|uniprotkb:th(gene name synonym)|uniprotkb:CG12284(orf name)|uniprotkb:RING-type E3 ubiquitin transferase Diap1(gene name synonym) psi-mi:dronc_drome(display_long)|uniprotkb:Dronc(gene name)|psi-mi:Dronc(display_short)|uniprotkb:NEDD2-like caspase(gene name synonym)|uniprotkb:Nc(gene name synonym)|uniprotkb:CG8091(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873758 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524101.2|refseq:NP_730097.1|refseq:NP_730098.1|flybase:FBgn0260635|refseq:NP_001261916.1|refseq:NP_001261917.1|refseq:NP_001261918.1|go:"GO:0006915"(apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0022416"(chaeta development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0045116"(protein neddylation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|ensemblmetazoa:FBgn0260635(gene)|ensemblmetazoa:FBtr0075499(transcript)|ensemblmetazoa:FBtr0075500(transcript)|ensemblmetazoa:FBtr0075501(transcript)|ensemblmetazoa:FBtr0333617(transcript)|ensemblmetazoa:FBtr0333618(transcript)|ensemblmetazoa:FBtr0333619(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|mint:Q24306|rcsb pdb:1JD4|rcsb pdb:1JD5|rcsb pdb:1JD6|rcsb pdb:1Q4Q|rcsb pdb:1SDZ|rcsb pdb:1SE0|rcsb pdb:3SIP|rcsb pdb:3SIQ|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-3769402|reactome:R-DME-390150|reactome:R-DME-5675482|reactome:R-DME-8948747|reactome:R-DME-8948751 refseq:NP_524017.1|flybase:FBgn0026404|dip:DIP-31484N|ensemblmetazoa:FBgn0026404(gene)|ensemblmetazoa:FBtr0076347(transcript)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007516"(hemocyte development)|go:"GO:0007552"(metamorphosis)|go:"GO:0008258"(head involution)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010623"(programmed cell death involved in cell development)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0010941"(regulation of cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0022416"(chaeta development)|go:"GO:0031638"(zymogen activation)|go:"GO:0035006"(melanization defense response)|go:"GO:0035070"(salivary gland histolysis)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043293"(apoptosome)|go:"GO:0045476"(nurse cell apoptotic process)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050700"(CARD domain binding)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|interpro:IPR033139|rcsb pdb:1Q4Q|rcsb pdb:2FP3|rcsb pdb:3J9K|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-140342|reactome:R-DME-198323|reactome:R-DME-264870|reactome:R-DME-351906|reactome:R-DME-418889|reactome:R-DME-448706|reactome:R-DME-449836 pubmed:10825159(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:loBQ//cKQ1NYhq3gnIKwRBn5vZg7227 rogid:5OjYCr0Yvr0eiWhfG14i20fZwNA7227 intact-crc:48801FB72F8D7AF6|rigid:qalCjviB3SHZ6V5+m8m9iok9OG8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20480 uniprotkb:P20480 intact:EBI-84482|uniprotkb:Q9VAG8|ensemblmetazoa:FBpp0084900|ensemblmetazoa:FBpp0311231 intact:EBI-84482|uniprotkb:Q9VAG8|ensemblmetazoa:FBpp0084900|ensemblmetazoa:FBpp0311231 psi-mi:ncd_drome(display_long)|uniprotkb:ncd(gene name)|psi-mi:ncd(display_short)|uniprotkb:"CA(ND)"(gene name synonym)|uniprotkb:CG7831(orf name) psi-mi:ncd_drome(display_long)|uniprotkb:ncd(gene name)|psi-mi:ncd(display_short)|uniprotkb:"CA(ND)"(gene name synonym)|uniprotkb:CG7831(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873762 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0031534"(minus-end directed microtubule sliding)|go:"GO:0032837"(distributive segregation)|ensemblmetazoa:FBtr0344976(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0072687"(meiotic spindle)|ensemblmetazoa:FBgn0002924(gene)|ensemblmetazoa:FBtr0085534(transcript)|rcsb pdb:3U06|rcsb pdb:5HLE|rcsb pdb:5HNW|rcsb pdb:5HNX|rcsb pdb:5HNY|rcsb pdb:5HNZ|rcsb pdb:5W3D|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:1CZ7|rcsb pdb:1N6M|rcsb pdb:1OZX|rcsb pdb:1SYJ|rcsb pdb:1SYP|rcsb pdb:1SZ4|rcsb pdb:1SZ5|rcsb pdb:2NCD|rcsb pdb:3L1C|refseq:NP_476651.1|flybase:FBgn0002924|refseq:NP_001287592.1|dip:DIP-21302N go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0031534"(minus-end directed microtubule sliding)|go:"GO:0032837"(distributive segregation)|ensemblmetazoa:FBtr0344976(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0072687"(meiotic spindle)|ensemblmetazoa:FBgn0002924(gene)|ensemblmetazoa:FBtr0085534(transcript)|rcsb pdb:3U06|rcsb pdb:5HLE|rcsb pdb:5HNW|rcsb pdb:5HNX|rcsb pdb:5HNY|rcsb pdb:5HNZ|rcsb pdb:5W3D|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|rcsb pdb:1CZ7|rcsb pdb:1N6M|rcsb pdb:1OZX|rcsb pdb:1SYJ|rcsb pdb:1SYP|rcsb pdb:1SZ4|rcsb pdb:1SZ5|rcsb pdb:2NCD|rcsb pdb:3L1C|refseq:NP_476651.1|flybase:FBgn0002924|refseq:NP_001287592.1|dip:DIP-21302N pubmed:11278404(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8sydvdYOvP3j1aqufTIH/rvDyJw7227 rogid:8sydvdYOvP3j1aqufTIH/rvDyJw7227 intact-crc:6DFA33A9F28B0F6D|rigid:XSOmHDj9oiweCwt2579gB4h1a2s false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O02194 uniprotkb:Q9VC27 intact:EBI-255741|uniprotkb:O02395|uniprotkb:O76802|uniprotkb:O96340|uniprotkb:Q9TY80|uniprotkb:Q9V3L9|uniprotkb:Q9V3S1|ensemblmetazoa:FBpp0077850|ensemblmetazoa:FBpp0305666 intact:EBI-170442|ensemblmetazoa:FBpp0084083|ensemblmetazoa:FBpp0291079 psi-mi:psn_drome(display_long)|uniprotkb:Psn(gene name)|psi-mi:Psn(display_short)|uniprotkb:PS(gene name synonym)|uniprotkb:CG18803(orf name)|uniprotkb:dPS(gene name synonym) psi-mi:nica_drome(display_long)|uniprotkb:Nct(gene name)|psi-mi:Nct(display_short)|uniprotkb:NCSTN(gene name synonym)|uniprotkb:CG7012(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873766 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0284421|refseq:NP_524184.1|refseq:NP_730535.1|refseq:NP_001262110.1|refseq:NP_001262111.1|dip:DIP-1139N|ensemblmetazoa:FBgn0284421(gene)|ensemblmetazoa:FBtr0078192(transcript)|ensemblmetazoa:FBtr0333479(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006508"(proteolysis)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0009986"(cell surface)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030018"(Z disc)|go:"GO:0030426"(growth cone)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035333"(Notch receptor processing, ligand-dependent)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0070765"(gamma-secretase complex)|interpro:IPR001108(Peptidase A22A, presenilin)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR042524|reactome:R-DME-1251985|reactome:R-DME-3928665|reactome:R-DME-6798695 refseq:NP_001163713.1|refseq:NP_651297.2|flybase:FBgn0039234|ensemblmetazoa:FBgn0039234(gene)|ensemblmetazoa:FBtr0084705(transcript)|ensemblmetazoa:FBtr0301865(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0016485"(protein processing)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0035333"(Notch receptor processing, ligand-dependent)|go:"GO:0045314"(regulation of compound eye photoreceptor development)|go:"GO:0046331"(lateral inhibition)|go:"GO:0055037"(recycling endosome)|go:"GO:0070765"(gamma-secretase complex)|interpro:IPR008710(Nicastrin)|interpro:IPR041084|reactome:R-DME-1251985|reactome:R-DME-3928665|reactome:R-DME-6798695|dip:DIP-23689N pubmed:11782315(see-also)|pubmed:11781576(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:UZooKoj+G0I4jZIcHgX+55Nlw887227 rogid:/w1uFC4hJyPDuSpdh5Ldhl4dNts7227 intact-crc:912D3508A5C4D067|rigid:WDk6wX/UHhYTlHb68dzxwwElf8E false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P98159 uniprotkb:P98159 intact:EBI-187386|uniprotkb:Q9VRX5|ensemblmetazoa:FBpp0076693 intact:EBI-187386|uniprotkb:Q9VRX5|ensemblmetazoa:FBpp0076693 psi-mi:nudel_drome(display_long)|uniprotkb:ndl(gene name)|psi-mi:ndl(display_short)|uniprotkb:CG10129(orf name) psi-mi:nudel_drome(display_long)|uniprotkb:ndl(gene name)|psi-mi:ndl(display_short)|uniprotkb:CG10129(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873770 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523947.2|flybase:FBgn0002926|ensemblmetazoa:FBgn0002926(gene)|ensemblmetazoa:FBtr0076984(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|go:"GO:0007306"(eggshell chorion assembly)|go:"GO:0007313"(maternal specification of dorsal/ventral axis, oocyte, soma encoded)|go:"GO:0007343"(egg activation)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0031638"(zymogen activation)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0098595"(perivitelline space)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR015420(Region of unknown function DUF1986)|interpro:IPR018114|interpro:IPR023415|interpro:IPR033116|interpro:IPR034381|interpro:IPR036055|interpro:IPR043504 refseq:NP_523947.2|flybase:FBgn0002926|ensemblmetazoa:FBgn0002926(gene)|ensemblmetazoa:FBtr0076984(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|go:"GO:0007306"(eggshell chorion assembly)|go:"GO:0007313"(maternal specification of dorsal/ventral axis, oocyte, soma encoded)|go:"GO:0007343"(egg activation)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0031638"(zymogen activation)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0098595"(perivitelline space)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR015420(Region of unknown function DUF1986)|interpro:IPR018114|interpro:IPR023415|interpro:IPR033116|interpro:IPR034381|interpro:IPR036055|interpro:IPR043504 pubmed:10628985(see-also)|pubmed:9735365(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:wlPAa2tNKOd2pv+U684zR5rwilg7227 rogid:wlPAa2tNKOd2pv+U684zR5rwilg7227 intact-crc:D5B14236D0E40DE5|rigid:hJYJlbtAYEDc0XKGEiYu83qv+n8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P12982 uniprotkb:O16866 intact:EBI-152633|uniprotkb:Q4PIY5|uniprotkb:Q9VG75|ensemblmetazoa:FBpp0082067 intact:EBI-870347|uniprotkb:O02030|uniprotkb:O18389 psi-mi:pp12_drome(display_long)|uniprotkb:Pp1-87B(gene name)|psi-mi:Pp1-87B(display_short)|uniprotkb:CG5650(orf name) psi-mi:o16866_drome(display_long)|uniprotkb:neb(gene name)|psi-mi:neb(display_short)|uniprotkb:CG10718(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873774 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524937.1|flybase:FBgn0004103|ensemblmetazoa:FBgn0004103(gene)|ensemblmetazoa:FBtr0082595(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007611"(learning or memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008355"(olfactory learning)|go:"GO:0008542"(visual learning)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030261"(chromosome condensation)|go:"GO:0040011"(locomotion)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|go:"GO:0005737"(cytoplasm)|reactome:R-DME-350416|reactome:R-DME-350480|reactome:R-DME-538898|go:"GO:0005700"(polytene chromosome)|dip:DIP-18465N flybase:FBgn0004374|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0048477"(oogenesis)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961 pubmed:12358598(see-also)|pubmed:12750335(see-also)|pubmed:9230081(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:wYZDYWZEbdafO7gAM+avnFnIF9Q7227 rogid:3gp/2P097AFdcpAlrImxMUQ7i/s7227 intact-crc:CC0369133AD2CA93|rigid:/rlKcxTHnjVh31/an9tCnGBD4po false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20659 uniprotkb:O01368 intact:EBI-591327|ensemblmetazoa:FBpp0082406|ensemblmetazoa:FBpp0082409|uniprotkb:Q27255|uniprotkb:Q27327|uniprotkb:Q8INF9|uniprotkb:Q960R2|uniprotkb:Q9VFL1|uniprotkb:A4V2V9|uniprotkb:A4V2W0|intact:EBI-3404288|intact:EBI-3417031|intact:EBI-9922180|intact:EBI-9933604 intact:EBI-868028 psi-mi:trx_drome(display_long)|uniprotkb:KMT2A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2A(gene name synonym)|uniprotkb:trx(gene name)|psi-mi:trx(display_short)|uniprotkb:CG8651(orf name)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:o01368_drome(display_long)|uniprotkb:nej(gene name)|psi-mi:nej(display_short)|uniprotkb:CG15319(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873778 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0003862(gene)|ensemblmetazoa:FBtr0082947(transcript)|ensemblmetazoa:FBtr0082950(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|reactome:R-DME-8936459|reactome:R-DME-8939236|refseq:NP_001014621.1|refseq:NP_476769.1|refseq:NP_476770.1|refseq:NP_599108.1|refseq:NP_599109.1|flybase:FBgn0003862 flybase:FBgn0261617|dip:DIP-41329N|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008347"(glial cell migration)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016573"(histone acetylation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0043971"(histone H3-K18 acetylation)|go:"GO:0043974"(histone H3-K27 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043993"("histone acetyltransferase activity (H3-K18 specific)")|go:"GO:0044017"("histone acetyltransferase activity (H3-K27 specific)")|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0098793"(presynapse)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR038547|interpro:IPR043145|mint:O01368 pubmed:11701926(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:LDT4/pLaHAuL/kuZMReRH9ZDrNk7227 rogid:JrQCBD9JpkCR4jgg0/08mthcy5o7227 intact-crc:52C1B8AF0D3F6C72|rigid:CTia8JbAuQomhBlle08F1XDRQpM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VK34 uniprotkb:O01368 intact:EBI-83837|ensemblmetazoa:FBpp0080015|intact:EBI-869173|uniprotkb:D5SHQ6|uniprotkb:O96505 intact:EBI-868028 psi-mi:sirt1_drome(display_long)|uniprotkb:Sirt1(gene name)|psi-mi:Sirt1(display_short)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Sir2(gene name synonym)|uniprotkb:CG5216(orf name) psi-mi:o01368_drome(display_long)|uniprotkb:nej(gene name)|psi-mi:nej(display_short)|uniprotkb:CG15319(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873782 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0024291(gene)|ensemblmetazoa:FBtr0080434(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016740"(transferase activity)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046872"(metal ion binding)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:1901416"(regulation of response to ethanol)|go:"GO:2000253"(positive regulation of feeding behavior)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|reactome:R-DME-9617629|refseq:NP_477351.1|flybase:FBgn0024291 flybase:FBgn0261617|dip:DIP-41329N|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008347"(glial cell migration)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016573"(histone acetylation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0043971"(histone H3-K18 acetylation)|go:"GO:0043974"(histone H3-K27 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043993"("histone acetyltransferase activity (H3-K18 specific)")|go:"GO:0044017"("histone acetyltransferase activity (H3-K27 specific)")|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0098793"(presynapse)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR038547|interpro:IPR043145|mint:O01368 pubmed:12524341(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:c+w67u0SypZji7O8yy/JsMFtAeA7227 rogid:JrQCBD9JpkCR4jgg0/08mthcy5o7227 intact-crc:D382002B65061A8E|rigid:il+ujngmaJjfHsSlgfiZq+heXCY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P91943 uniprotkb:O01368 intact:EBI-147301|uniprotkb:O02548|uniprotkb:Q0KIE9|intact:EBI-1629313|uniprotkb:Q59DP5|uniprotkb:Q5BHZ3|uniprotkb:Q6W492|uniprotkb:Q6W493|uniprotkb:Q6W494|uniprotkb:Q6W495|uniprotkb:Q6W4A6|uniprotkb:Q6W4B4|uniprotkb:Q9V4B0|uniprotkb:A0AVW4|uniprotkb:A4V148|uniprotkb:B5RJS3|ensemblmetazoa:FBpp0088226|ensemblmetazoa:FBpp0088228|ensemblmetazoa:FBpp0088229|ensemblmetazoa:FBpp0301556 intact:EBI-868028 psi-mi:pang1_drome(display_long)|uniprotkb:pan(gene name)|psi-mi:pan(display_short)|uniprotkb:TCF(gene name synonym)|uniprotkb:dTCF(gene name synonym)|uniprotkb:CG34403(orf name) psi-mi:o01368_drome(display_long)|uniprotkb:nej(gene name)|psi-mi:nej(display_short)|uniprotkb:CG15319(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873786 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245406.1|refseq:NP_001014685.1|refseq:NP_001033798.1|refseq:NP_524619.3|refseq:NP_726522.1|refseq:NP_726524.1|flybase:FBgn0085432|refseq:NP_726527.2|dip:DIP-19970N|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019900"(kinase binding)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR028782|interpro:IPR036910|reactome:R-DME-209421|reactome:R-DME-209441|ensemblmetazoa:FBgn0085432(gene)|ensemblmetazoa:FBtr0089159(transcript)|ensemblmetazoa:FBtr0089161(transcript)|ensemblmetazoa:FBtr0089162(transcript)|ensemblmetazoa:FBtr0309803(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific) flybase:FBgn0261617|dip:DIP-41329N|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008347"(glial cell migration)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016573"(histone acetylation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0043971"(histone H3-K18 acetylation)|go:"GO:0043974"(histone H3-K27 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0043993"("histone acetyltransferase activity (H3-K18 specific)")|go:"GO:0044017"("histone acetyltransferase activity (H3-K27 specific)")|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048749"(compound eye development)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0098793"(presynapse)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR038547|interpro:IPR043145|mint:O01368 pubmed:9774110(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:H6BhYVP6spDgW8etHP7+/L29jO87227 rogid:JrQCBD9JpkCR4jgg0/08mthcy5o7227 intact-crc:3C9B2E411DF205FC|rigid:2BOynxYwCuNN95IkmewPezgMSUk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q05547 uniprotkb:Q9V7W9 intact:EBI-157144|uniprotkb:Q9VXW0|ensemblmetazoa:FBpp0073834 intact:EBI-108894|ensemblmetazoa:FBpp0086206 psi-mi:pp13_drome(display_long)|uniprotkb:Pp1-13C(gene name)|psi-mi:Pp1-13C(display_short)|uniprotkb:CG9156(orf name) psi-mi:q9v7w9_drome(display_long)|uniprotkb:NiPp1(gene name)|psi-mi:NiPp1(display_short)|uniprotkb:NIPP-1Dm(gene name synonym)|uniprotkb:Dmel\CG8980(gene name synonym)|uniprotkb:NIPP1(gene name synonym)|uniprotkb:NIPP1Dm(gene name synonym)|uniprotkb:NiPp-1(gene name synonym)|uniprotkb:nipp1(gene name synonym)|uniprotkb:CG8980(orf name)|uniprotkb:Dmel_CG8980(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873796 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524921.1|flybase:FBgn0003132|dip:DIP-23332N|ensemblmetazoa:FBgn0003132(gene)|ensemblmetazoa:FBtr0074017(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046692"(sperm competition)|go:"GO:0046872"(metal ion binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|reactome:R-DME-538898 refseq:NP_611177.1|flybase:FBgn0026402|ensemblmetazoa:FBgn0026402(gene)|ensemblmetazoa:FBtr0087058(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007411"(axon guidance)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) pubmed:9230081(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:3Asj1ctAhmzU9rsIbIwDdRufFdc7227 rogid:rdBh9IGE11vnHzjmdmopB1cGt+U7227 intact-crc:5B2C48F33FFF7457|rigid:SxCvzpH7WD+g5toTgWjmO1upDCw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P41073 uniprotkb:Q04047 intact:EBI-522331|uniprotkb:Q8IGB1|uniprotkb:Q8MSV5|uniprotkb:Q9VVJ2|uniprotkb:Q9VVJ3|uniprotkb:Q9VVJ4|ensemblmetazoa:FBpp0074963 intact:EBI-134012|uniprotkb:Q24261|uniprotkb:Q59E42|uniprotkb:Q9VXH1|ensemblmetazoa:FBpp0074011|ensemblmetazoa:FBpp0309274 psi-mi:pep_drome(display_long)|uniprotkb:Pep(gene name)|psi-mi:Pep(display_short)|uniprotkb:CG6143(orf name) psi-mi:nona_drome(display_long)|uniprotkb:nonA(gene name)|psi-mi:nonA(display_short)|uniprotkb:CG4211(orf name)|uniprotkb:Puff-specific protein Bj6(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873800 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524858.1|refseq:NP_730290.3|refseq:NP_996118.1|flybase:FBgn0004401|ensemblmetazoa:FBgn0004401(gene)|ensemblmetazoa:FBtr0075199(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR026811|interpro:IPR036236|mint:P41073|dip:DIP-20217N|refseq:NP_001246817.1 refseq:NP_001014747.1|refseq:NP_523367.2|flybase:FBgn0004227|refseq:NP_001285324.1|ensemblmetazoa:FBgn0004227(gene)|ensemblmetazoa:FBtr0074232(transcript)|ensemblmetazoa:FBtr0340313(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007601"(visual perception)|go:"GO:0007632"(visual behavior)|go:"GO:0042331"(phototaxis)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR035979|mint:Q04047 pubmed:10585281(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:29/JZMsZ78Uyh3MQGEfFkmct0S87227 rogid:4ART7xru9saoL461MJiyASUWfLo7227 intact-crc:1C1C4DF3F2A35CF9|rigid:T+GQ2LSiL3eBuMjTrqgfcSCoqNM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P25822 uniprotkb:P25724 intact:EBI-252055|uniprotkb:A4V2K5|uniprotkb:Q5BIA7|uniprotkb:Q7YU65|uniprotkb:Q9VHH4|uniprotkb:Q9VHH6|uniprotkb:Q8IGA8|ensemblmetazoa:FBpp0081470|ensemblmetazoa:FBpp0081471|ensemblmetazoa:FBpp0081472|ensemblmetazoa:FBpp0305823 intact:EBI-106556|uniprotkb:Q9VDZ6|ensemblmetazoa:FBpp0083146 psi-mi:pum_drome(display_long)|uniprotkb:pum(gene name)|psi-mi:pum(display_short)|uniprotkb:CG9755(orf name) psi-mi:nanos_drome(display_long)|uniprotkb:nos(gene name)|psi-mi:nos(display_short)|uniprotkb:CG5637(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873804 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524285.2|refseq:NP_731314.1|refseq:NP_731315.1|refseq:NP_731316.2|refseq:NP_788604.1|flybase:FBgn0003165|refseq:NP_001262403.1|ensemblmetazoa:FBgn0003165(gene)|ensemblmetazoa:FBtr0081990(transcript)|ensemblmetazoa:FBtr0081991(transcript)|ensemblmetazoa:FBtr0081992(transcript)|ensemblmetazoa:FBtr0333667(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007280"(pole cell migration)|go:"GO:0007281"(germ cell development)|go:"GO:0007616"(long-term memory)|go:"GO:0008258"(head involution)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0016477"(cell migration)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061177"(type Is terminal bouton)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901835"(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:1905762"(CCR4-NOT complex binding)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR033712|rcsb pdb:3H3D|rcsb pdb:5KL1|rcsb pdb:5KL8|rcsb pdb:5KLA|reactome:R-DME-432722 refseq:NP_476658.1|flybase:FBgn0002962|dip:DIP-23696N|ensemblmetazoa:FBgn0002962(gene)|ensemblmetazoa:FBtr0083732(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007280"(pole cell migration)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035282"(segmentation)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045495"(pole plasm)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0098975"(postsynapse of neuromuscular junction)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR008705(Zinc finger, Nanos)|interpro:IPR024161|interpro:IPR038129|rcsb pdb:5KL1|rcsb pdb:5KL8 pubmed:11336677(see-also)|pubmed:10541556(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:z0jqCHqL2L2hUrWEa1pQiksf6hs7227 rogid:Odk9EPZ9mhtw2sC1379nInFonas7227 intact-crc:F9C3504F4384EE63|rigid:9z6+fgRPqv6zTZ8K2mPy42ei3lw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q27571 uniprotkb:Q27571 intact:EBI-250644|uniprotkb:A4V0K9|uniprotkb:A4V0L0|uniprotkb:Q4ABG3|uniprotkb:Q4ABG4|uniprotkb:Q4ABG5|uniprotkb:Q4ABG6|uniprotkb:Q4ABG7|uniprotkb:Q7YU33|uniprotkb:Q9U096|uniprotkb:Q9VKP8|ensemblmetazoa:FBpp0079777 intact:EBI-250644|uniprotkb:A4V0K9|uniprotkb:A4V0L0|uniprotkb:Q4ABG3|uniprotkb:Q4ABG4|uniprotkb:Q4ABG5|uniprotkb:Q4ABG6|uniprotkb:Q4ABG7|uniprotkb:Q7YU33|uniprotkb:Q9U096|uniprotkb:Q9VKP8|ensemblmetazoa:FBpp0079777 psi-mi:nos_drome(display_long)|uniprotkb:Nos(gene name)|psi-mi:Nos(display_short)|uniprotkb:CG6713(orf name)|uniprotkb:dNOS(gene name synonym) psi-mi:nos_drome(display_long)|uniprotkb:Nos(gene name)|psi-mi:Nos(display_short)|uniprotkb:CG6713(orf name)|uniprotkb:dNOS(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873808 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027243.2|refseq:NP_001027240.1|refseq:NP_523541.2|flybase:FBgn0011676|ensemblmetazoa:FBgn0011676(gene)|ensemblmetazoa:FBtr0080188(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007416"(synapse assembly)|go:"GO:0007444"(imaginal disc development)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0010181"(FMN binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0020037"(heme binding)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036119|interpro:IPR039261|rcsb pdb:2I86|reactome:R-DME-1222556|reactome:R-DME-1474151|reactome:R-DME-203615|reactome:R-DME-203754|reactome:R-DME-392154|reactome:R-DME-5218920|reactome:R-DME-5578775|reactome:R-DME-9009391|reactome:R-DME-9033241 refseq:NP_001027243.2|refseq:NP_001027240.1|refseq:NP_523541.2|flybase:FBgn0011676|ensemblmetazoa:FBgn0011676(gene)|ensemblmetazoa:FBtr0080188(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007416"(synapse assembly)|go:"GO:0007444"(imaginal disc development)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0010181"(FMN binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0020037"(heme binding)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036119|interpro:IPR039261|rcsb pdb:2I86|reactome:R-DME-1222556|reactome:R-DME-1474151|reactome:R-DME-203615|reactome:R-DME-203754|reactome:R-DME-392154|reactome:R-DME-5218920|reactome:R-DME-5578775|reactome:R-DME-9009391|reactome:R-DME-9033241 pubmed:11526108(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KhGh/FIAYXuRXtDSb+P232renhY7227 rogid:KhGh/FIAYXuRXtDSb+P232renhY7227 intact-crc:FE0D7953701A2380|rigid:pKFZk7zff1PO2NnYmIeZrMl9xmg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09615 intact:EBI-870367 intact:EBI-98242|uniprotkb:Q27768|uniprotkb:Q27769|uniprotkb:Q8IPI1|uniprotkb:Q8MQP9|uniprotkb:Q9VM27|ensemblmetazoa:FBpp0079060 - psi-mi:wntg_drome(display_long)|uniprotkb:Protein Wnt-1(gene name synonym)|uniprotkb:Protein int-1(gene name synonym)|uniprotkb:CG4889(orf name)|uniprotkb:wg(gene name)|psi-mi:wg(display_short)|uniprotkb:dWnt-1(gene name synonym)|uniprotkb:dInt-1(gene name synonym) psi-mi:q8iqn5_drome(display_short)|psi-mi:EBI-870367(display_long)|uniprotkb:Notum(gene name)|psi-mi:Notum(display_short)|uniprotkb:Dmel_CG13076(orf name)|uniprotkb:CG13076(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873812 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523502.1|ensemblmetazoa:FBgn0284084(gene)|ensemblmetazoa:FBtr0079432(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007398"(ectoderm development)|go:"GO:0007418"(ventral midline development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007523"(larval visceral muscle development)|go:"GO:0007616"(long-term memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014019"(neuroblast development)|go:"GO:0016015"(morphogen activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0061328"(posterior Malpighian tubule development)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061332"(Malpighian tubule bud morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR043158|reactome:R-DME-201681|reactome:R-DME-209387|reactome:R-DME-209440|reactome:R-DME-209472|reactome:R-DME-3238698|reactome:R-DME-4086400|reactome:R-DME-4641262|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032876"(negative regulation of DNA endoreduplication)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035217"(labial disc development)|go:"GO:0035220"(wing disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035263"(genital disc sexually dimorphic development)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035311"(wing cell fate specification)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043195"(terminal bouton)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048332"(mesoderm morphogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048728"(proboscis development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050808"(synapse organization)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0060061"(Spemann organizer formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060914"(heart formation)|go:"GO:0061316"(canonical Wnt signaling pathway involved in heart development)|go:"GO:0045572"(positive regulation of imaginal disc growth)|flybase:FBgn0284084|dip:DIP-21777N uniprotkb:Q8IQN5(uniprot-removed-ac) pubmed:12000788(see-also) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ioGPXpHjZchgMT2/PR2ivC4Jo+s7227 rogid:oi+gt6KA4rb6RiPreRPcJVWBTB07227 intact-crc:B050638061ADEEC4|rigid:Q9iKCdV36WtMPDiMlaomlpHQ0AA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O96561 uniprotkb:P16554 intact:EBI-870379 intact:EBI-429581|uniprotkb:Q8IPE9|uniprotkb:Q961A6|uniprotkb:Q9VLB8|uniprotkb:B8A413|uniprotkb:B8A419|ensemblmetazoa:FBpp0079420|ensemblmetazoa:FBpp0308609 psi-mi:o96561_drome(display_long)|uniprotkb:pon(gene name)|psi-mi:pon(display_short)|uniprotkb:CG3346(orf name) psi-mi:numb_drome(display_long)|uniprotkb:CG3779(orf name)|uniprotkb:numb(gene name)|psi-mi:numb(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873816 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0025739|dip:DIP-46780N|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0045178"(basal part of cell)|go:"GO:0055059"(asymmetric neuroblast division)|rcsb pdb:5J19 refseq:NP_523523.2|refseq:NP_723460.1|flybase:FBgn0002973|refseq:NP_001260291.1|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051642"(centrosome localization)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|mint:P16554|go:"GO:0045178"(basal part of cell)|rcsb pdb:1DDM|rcsb pdb:2NMB|rcsb pdb:5YI7|rcsb pdb:5YI8|reactome:R-DME-5610780|reactome:R-DME-5632684|ensemblmetazoa:FBgn0002973(gene)|ensemblmetazoa:FBtr0079822(transcript)|ensemblmetazoa:FBtr0339526(transcript)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005112"(Notch binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008104"(protein localization)|go:"GO:0008347"(glial cell migration)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0045035"(sensory organ precursor cell division) pubmed:9790529(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:UMAEAmrNpiQekl6kezCIIdfRjmI7227 rogid:9FGhbcAA6k1LCDHPoLSXwEEVwzY7227 intact-crc:D21733A65C8EAD63|rigid:r7uemrEnqW26pjsAFF7Mzuu/FPk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24037 uniprotkb:O96681 intact:EBI-870387|ensemblmetazoa:FBpp0303462 intact:EBI-870234 psi-mi:q24037_drome(display_long)|uniprotkb:nvy(gene name)|psi-mi:nvy(display_short)|uniprotkb:CG3385(orf name) psi-mi:o96681_drome(display_long)|uniprotkb:PlexA(gene name)|psi-mi:PlexA(display_short)|uniprotkb:plexA(gene name synonym)|uniprotkb:CG11081(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873820 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0005636|ensemblmetazoa:FBgn0005636(gene)|ensemblmetazoa:FBtr0330612(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0007411"(axon guidance)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013293(Nervy)|interpro:IPR014896(NHR2-like)|interpro:IPR037249 flybase:FBgn0025741|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0030250"(guanylate cyclase activator activity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097374"(sensory neuron axon guidance)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:2000305"(semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362 pubmed:14976319(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:9iPZS5xB/+txTRYMy6QzhttvgWc7227 rogid:+9+nmrm+OrwkG/mEh1tqH0IC5C47227 intact-crc:DF792588DE9CFAA2|rigid:JQkVaYOUFEnLOwTHwmKcSZtPqZM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9U1H9 uniprotkb:Q9V3H8 intact:EBI-144932|uniprotkb:Q9NFQ2|uniprotkb:Q9NFQ3|uniprotkb:Q9VZ65|uniprotkb:Q9VZ68|intact:EBI-1631872|ensemblmetazoa:FBpp0073267 intact:EBI-160435|ensemblmetazoa:FBpp0072150 psi-mi:nxf1_drome(display_long)|uniprotkb:sbr(gene name)|psi-mi:sbr(display_short)|uniprotkb:nxf1(gene name synonym)|uniprotkb:CG1664(orf name)|uniprotkb:Protein tip-associating(gene name synonym)|uniprotkb:Protein small bristles(gene name synonym) psi-mi:nxt1_drome(display_long)|uniprotkb:CG12752(orf name)|uniprotkb:Nxt1(gene name)|psi-mi:Nxt1(display_short)|uniprotkb:p15(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873824 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524660.1|flybase:FBgn0003321|dip:DIP-21726N|ensemblmetazoa:FBgn0003321(gene)|ensemblmetazoa:FBtr0073411(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051168"(nuclear export)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|rcsb pdb:6IHJ|reactome:R-DME-159227|reactome:R-DME-159230|reactome:R-DME-159231|reactome:R-DME-159236 refseq:NP_611833.1|flybase:FBgn0028411|interpro:IPR018222|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR032710|rcsb pdb:6IHJ|rcsb pdb:6MRK|reactome:R-DME-159236|ensemblmetazoa:FBgn0028411(gene)|ensemblmetazoa:FBtr0072241(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium) pubmed:11780633(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:vM7nPfCYR9AKpLOc0lKKXZIfkmk7227 rogid:Z0IetjQoCtdLXyR7Oz2i+JNX1ic7227 intact-crc:D73270FCDE79607E|rigid:t+8JiU3typ4zVeJ+UAKAyoFSXfw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P05205 uniprotkb:O16810 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873828 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N pubmed:9679132(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 intact-crc:B45DCA68F028C44A|rigid:bLtM94shHbmkFkxaXZtSNZB7h3U false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P05205 uniprotkb:Q24168 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 intact:EBI-179453|intact:EBI-1631787|uniprotkb:Q9VFP4|ensemblmetazoa:FBpp0082329 psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:orc2_drome(display_long)|uniprotkb:Orc2(gene name)|psi-mi:Orc2(display_short)|uniprotkb:CG3041(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873832 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA refseq:NP_731873.1|flybase:FBgn0015270|dip:DIP-23209N|ensemblmetazoa:FBgn0015270(gene)|ensemblmetazoa:FBtr0082866(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005723"(alpha-heterochromatin)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0030261"(chromosome condensation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 pubmed:9679132(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 rogid:SaBA2xfoQcWtCiLhN6rD5O5yMhg7227 intact-crc:F7AEDCDC41834FF1|rigid:NroXfMdRIS6tmfpce6eoG0S8XXc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40797 uniprotkb:Q9Y1B2 intact:EBI-171301|uniprotkb:Q0E9F5|uniprotkb:Q9V385|ensemblmetazoa:FBpp0087869|ensemblmetazoa:FBpp0087870 intact:EBI-113296|uniprotkb:Q9V5C5|ensemblmetazoa:FBpp0087566 psi-mi:pnut_drome(display_long)|uniprotkb:pnut(gene name)|psi-mi:pnut(display_short)|uniprotkb:CG8705(orf name) psi-mi:orc6_drome(display_long)|uniprotkb:Orc6(gene name)|psi-mi:Orc6(display_short)|uniprotkb:CG1584(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873836 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477064.1|refseq:NP_724659.1|flybase:FBgn0013726|dip:DIP-60735N|ensemblmetazoa:FBgn0013726(gene)|ensemblmetazoa:FBtr0088792(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|ensemblmetazoa:FBtr0088793(transcript)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070938"(contractile ring)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0060271"(cilium assembly) refseq:NP_477319.1|flybase:FBgn0023180|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|ensemblmetazoa:FBgn0023180(gene)|ensemblmetazoa:FBtr0088482(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000808"(origin recognition complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR020529|rcsb pdb:4XGC|rcsb pdb:7JGR|dip:DIP-49258N pubmed:12878722(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:AwSNOc8ecwdqxwA6z93hfsSa7g87227 rogid:1l2xkmHWJBVXCc+nGLx6RpjMec07227 intact-crc:1E9CC7626FCA75F3|rigid:1v6GqKBuQSG4lIgfMMjwFP46ZKM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09052 uniprotkb:P25158 intact:EBI-134067|uniprotkb:Q24582|uniprotkb:Q8SXU8|uniprotkb:Q9V3Q8|ensemblmetazoa:FBpp0401445|ensemblmetazoa:FBpp0401446|ensemblmetazoa:FBpp0401447 intact:EBI-103301|uniprotkb:Q59DY0|uniprotkb:Q95TT0|uniprotkb:Q9V3P1|ensemblmetazoa:FBpp0081435 psi-mi:vasa1_drome(display_long)|uniprotkb:vas(gene name)|psi-mi:vas(display_short)|uniprotkb:Antigen Mab46F11(gene name synonym)|uniprotkb:vasa(gene name synonym)|uniprotkb:CG46283(orf name) psi-mi:oska_drome(display_long)|uniprotkb:osk(gene name)|psi-mi:osk(display_short)|uniprotkb:CG10901(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873848 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283442|refseq:NP_723899.1|refseq:NP_001303322.1|refseq:NP_001260458.1|ensemblmetazoa:FBgn0283442(gene)|rcsb pdb:2IHS|rcsb pdb:3EMW|rcsb pdb:3F2O|rcsb pdb:5NT7|ensemblmetazoa:FBtr0445185(transcript)|ensemblmetazoa:FBtr0445186(transcript)|ensemblmetazoa:FBtr0445187(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0008104"(protein localization)|go:"GO:0030154"(cell differentiation)|go:"GO:0043073"(germ cell nucleus)|go:"GO:0043186"(P granule)|go:"GO:0048477"(oogenesis)|go:"GO:0061803"(posterior cell cortex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|mint:P09052|rcsb pdb:2DB3|dip:DIP-20604N refseq:NP_731295.1|refseq:NP_996186.1|flybase:FBgn0003015|ensemblmetazoa:FBgn0003015(gene)|ensemblmetazoa:FBtr0081954(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007279"(pole cell formation)|go:"GO:0007281"(germ cell development)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007359"(posterior abdomen determination)|go:"GO:0007616"(long-term memory)|go:"GO:0007632"(visual behavior)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008542"(visual learning)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0030719"(P granule organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035282"(segmentation)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0043073"(germ cell nucleus)|go:"GO:0043186"(P granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045495"(pole plasm)|go:"GO:0046011"(regulation of oskar mRNA translation)|go:"GO:0048477"(oogenesis)|go:"GO:0061803"(posterior cell cortex)|go:"GO:1903863"(P granule assembly)|interpro:IPR025605|interpro:IPR033447|interpro:IPR036514|interpro:IPR041966|rcsb pdb:5A48|rcsb pdb:5A49|rcsb pdb:5A4A|rcsb pdb:5CD7|rcsb pdb:5CD8|rcsb pdb:5CD9|rcsb pdb:5NT7|dip:DIP-18970N pubmed:8804312(see-also)|pubmed:8582284(see-also)|pubmed:8804312(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:MPzIr/Dex98V189t6FOs8l0nQnM7227 rogid:MJUHbKJPubbucg2qG4sxin4VhYk7227 intact-crc:EBF06950F14CC97D|rigid:qf92gtAoLJWiFppRU7ZO2Nsv2Xk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P25159 uniprotkb:P25158 intact:EBI-179533|intact:EBI-1630222|uniprotkb:Q6NQY8|uniprotkb:Q86PB7|uniprotkb:Q9V8B8|uniprotkb:Q9V8B9|ensemblmetazoa:FBpp0085962 intact:EBI-103301|uniprotkb:Q59DY0|uniprotkb:Q95TT0|uniprotkb:Q9V3P1|ensemblmetazoa:FBpp0081435 psi-mi:stau_drome(display_long)|uniprotkb:stau(gene name)|psi-mi:stau(display_short)|uniprotkb:CG5753(orf name) psi-mi:oska_drome(display_long)|uniprotkb:osk(gene name)|psi-mi:osk(display_short)|uniprotkb:CG10901(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873852 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163185.1|refseq:NP_476751.1|refseq:NP_725748.1|flybase:FBgn0003520|ensemblmetazoa:FBgn0003520(gene)|ensemblmetazoa:FBtr0086783(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006403"(RNA localization)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007316"(pole plasm RNA localization)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007616"(long-term memory)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045180"(basal cortex)|go:"GO:0045450"(bicoid mRNA localization)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046011"(regulation of oskar mRNA translation)|go:"GO:0048477"(oogenesis)|go:"GO:0060293"(germ plasm)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|rcsb pdb:1EKZ|rcsb pdb:1STU|rcsb pdb:5CFF refseq:NP_731295.1|refseq:NP_996186.1|flybase:FBgn0003015|ensemblmetazoa:FBgn0003015(gene)|ensemblmetazoa:FBtr0081954(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007279"(pole cell formation)|go:"GO:0007281"(germ cell development)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0007359"(posterior abdomen determination)|go:"GO:0007616"(long-term memory)|go:"GO:0007632"(visual behavior)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008542"(visual learning)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0030719"(P granule organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035282"(segmentation)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0043073"(germ cell nucleus)|go:"GO:0043186"(P granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045495"(pole plasm)|go:"GO:0046011"(regulation of oskar mRNA translation)|go:"GO:0048477"(oogenesis)|go:"GO:0061803"(posterior cell cortex)|go:"GO:1903863"(P granule assembly)|interpro:IPR025605|interpro:IPR033447|interpro:IPR036514|interpro:IPR041966|rcsb pdb:5A48|rcsb pdb:5A49|rcsb pdb:5A4A|rcsb pdb:5CD7|rcsb pdb:5CD8|rcsb pdb:5CD9|rcsb pdb:5NT7|dip:DIP-18970N pubmed:8804312(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8wlpvhd3GYYnc2+hayn2HjsYQ0A7227 rogid:MJUHbKJPubbucg2qG4sxin4VhYk7227 intact-crc:F39AB2485F904EAD|rigid:VdDYv7mwsEqE/CzUrdjbEDN76FA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O96681 uniprotkb:Q6AWJ9 intact:EBI-870234 intact:EBI-870398|uniprotkb:C4IXZ4|uniprotkb:Q24327|ensemblmetazoa:FBpp0087135 psi-mi:o96681_drome(display_long)|uniprotkb:PlexA(gene name)|psi-mi:PlexA(display_short)|uniprotkb:plexA(gene name synonym)|uniprotkb:CG11081(orf name) psi-mi:ptk7_drome(display_long)|uniprotkb:otk(gene name)|psi-mi:otk(display_short)|uniprotkb:Tyrosine-protein kinase-like 7 homolog(gene name synonym)|uniprotkb:Gp160-Dtrk(gene name synonym)|uniprotkb:Off-track(gene name synonym)|uniprotkb:CG8967(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873856 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0025741|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0030250"(guanylate cyclase activator activity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097374"(sensory neuron axon guidance)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:2000305"(semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362 refseq:NP_523705.2|flybase:FBgn0004839|ensemblmetazoa:FBgn0004839(gene)|ensemblmetazoa:FBtr0088028(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030424"(axon)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0035260"(internal genitalia morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048804"(imaginal disc-derived female genitalia morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR020635|interpro:IPR036179|rcsb pdb:6S9F pubmed:11604138(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+9+nmrm+OrwkG/mEh1tqH0IC5C47227 rogid:vwTxpB7q1KqInJJerF2Sa6kHsPE7227 intact-crc:E6C2F8BBDE87A6F0|rigid:BLT6rMhbIcaoKyKfTEByOf0x3MY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P48148 uniprotkb:Q7PLI0 intact:EBI-87246|uniprotkb:Q0E958|uniprotkb:Q9V3J0|ensemblmetazoa:FBpp0086353|ensemblmetazoa:FBpp0086354|ensemblmetazoa:FBpp0086355|ensemblmetazoa:FBpp0086356|ensemblmetazoa:FBpp0089129|ensemblmetazoa:FBpp0089130|uniprotkb:A4UZI6 intact:EBI-103506|ensemblmetazoa:FBpp0110406 psi-mi:rho1_drome(display_long)|uniprotkb:Rho1(gene name)|psi-mi:Rho1(display_short)|uniprotkb:CG8416(orf name) psi-mi:q7pli0_drome(display_long)|uniprotkb:p120ctn(gene name)|psi-mi:p120ctn(display_short)|uniprotkb:Dmel\CG17484(gene name synonym)|uniprotkb:Dp120[ctn](gene name synonym)|uniprotkb:Dp120ctn(gene name synonym)|uniprotkb:P120(gene name synonym)|uniprotkb:P120-catenin(gene name synonym)|uniprotkb:P120ctn(gene name synonym)|uniprotkb:dP120ctn(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:p120[ctn](gene name synonym)|uniprotkb:CG17484(orf name)|uniprotkb:Dmel_CG17484(orf name)|uniprotkb:dp120ctn(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873860 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0014020(gene)|ensemblmetazoa:FBtr0087211(transcript)|ensemblmetazoa:FBtr0087212(transcript)|ensemblmetazoa:FBtr0087213(transcript)|ensemblmetazoa:FBtr0087214(transcript)|ensemblmetazoa:FBtr0087216(transcript)|ensemblmetazoa:FBtr0087217(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007349"(cellularization)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007374"(posterior midgut invagination)|go:"GO:0007377"(germ-band extension)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0005737"(cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0070451"(cell hair)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0110020"(regulation of actomyosin structure organization)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-193634|reactome:R-DME-198203|reactome:R-DME-2173791|reactome:R-DME-350368|reactome:R-DME-350407|reactome:R-DME-350480|reactome:R-DME-392451|reactome:R-DME-3928662|reactome:R-DME-3928663|reactome:R-DME-4086400|interpro:IPR001806(Ras GTPase)|reactome:R-DME-416482|reactome:R-DME-416572|reactome:R-DME-4420097|reactome:R-DME-450728|reactome:R-DME-5625740|reactome:R-DME-5627117|reactome:R-DME-5663220|reactome:R-DME-5666185|reactome:R-DME-5689896|reactome:R-DME-6785631|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-8980692|reactome:R-DME-9013405|reactome:R-DME-9035034|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007601"(visual perception)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035006"(melanization defense response)|go:"GO:0035099"(hemocyte migration)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035298"(regulation of Malpighian tubule size)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0042060"(wound healing)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045179"(apical cortex)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046663"(dorsal closure, leading edge cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0035149"(lumen formation, open tracheal system)|refseq:NP_477098.1|refseq:NP_599135.1|refseq:NP_599136.1|refseq:NP_725524.1|refseq:NP_995849.1|refseq:NP_995850.1|flybase:FBgn0014020|dip:DIP-22676N go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0045296"(cadherin binding)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000225(Armadillo)|ensemblmetazoa:FBgn0260799(gene)|ensemblmetazoa:FBtr0111114(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|refseq:NP_001036444.1|flybase:FBgn0260799|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028446|reactome:R-DME-351906|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-6798695 pubmed:12135916(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:DbVx4weiFRCcGfqdsUQWqWQc0Q47227 rogid:L/I2OLF4GrIqDc92pIGYEeRU42I7227 intact-crc:1B4CF45EB3B5E75C|rigid:SZ9/Baq/Hd+7xbdCvZLAkjlrEXY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40792 uniprotkb:Q9VI13 intact:EBI-74845|uniprotkb:Q9W0H7|ensemblmetazoa:FBpp0072614|ensemblmetazoa:FBpp0304252 intact:EBI-74826|intact:EBI-123979|intact:EBI-466309|uniprotkb:Q24190|uniprotkb:Q24213|ensemblmetazoa:FBpp0081211|ensemblmetazoa:FBpp0081212|ensemblmetazoa:FBpp0081213|ensemblmetazoa:FBpp0306606|ensemblmetazoa:FBpp0306611 psi-mi:rac1_drome(display_long)|uniprotkb:Rac1(gene name)|psi-mi:Rac1(display_short)|uniprotkb:RacA(gene name synonym)|uniprotkb:CG2248(orf name) psi-mi:pak_drome(display_long)|uniprotkb:Pak(gene name)|psi-mi:Pak(display_short)|uniprotkb:DPAK(gene name synonym)|uniprotkb:Dpak1(gene name synonym)|uniprotkb:CG10295(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873864 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476950.1|flybase:FBgn0010333|refseq:NP_001261247.1|ensemblmetazoa:FBgn0010333(gene)|ensemblmetazoa:FBtr0072730(transcript)|ensemblmetazoa:FBtr0331868(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002433"(immune response-regulating cell surface receptor signaling pathway involved in phagocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007394"(dorsal closure, elongation of leading edge cells)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007516"(hemocyte development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007613"(memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008258"(head involution)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0016028"(rhabdomere)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016203"(muscle attachment)|go:"GO:0016358"(dendrite development)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035010"(encapsulation of foreign target)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0035320"(imaginal disc-derived wing hair site selection)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048675"(axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0055001"(muscle cell development)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097206"(nephrocyte filtration)|go:"GO:0110125"(negative regulation of myotube cell migration)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1903391"(regulation of adherens junction organization)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-1433557|reactome:R-DME-193648|reactome:R-DME-2029482|reactome:R-DME-2871796|reactome:R-DME-350376|reactome:R-DME-376172|reactome:R-DME-389359|reactome:R-DME-3928662|reactome:R-DME-3928664|reactome:R-DME-3928665|reactome:R-DME-399954|reactome:R-DME-4086400|reactome:R-DME-4420097|reactome:R-DME-445144|reactome:R-DME-5218920|reactome:R-DME-5625740|reactome:R-DME-5627123|reactome:R-DME-5663213|reactome:R-DME-5687128|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-9013407|reactome:R-DME-9706019|reactome:R-DME-983231 flybase:FBgn0267698|refseq:NP_001262309.1|refseq:NP_001262313.1|refseq:NP_524681.1|refseq:NP_731073.1|refseq:NP_731074.1|ensemblmetazoa:FBgn0267698(gene)|ensemblmetazoa:FBtr0081714(transcript)|ensemblmetazoa:FBtr0081715(transcript)|ensemblmetazoa:FBtr0081716(transcript)|ensemblmetazoa:FBtr0334539(transcript)|ensemblmetazoa:FBtr0334544(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019991"(septate junction assembly)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936 pubmed:8628256(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2021/06/18 rogid:nVrsdRuWmYjJp67rd4Es0mFDuUU7227 rogid:B88kI/CaRk7fc0eQ5+Y4jk4zWwc7227 intact-crc:0B84252C32BFD71A|rigid:loWbXxe2q6dYxzB4+nQIlLV/SHE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O97118 uniprotkb:P35875 intact:EBI-870420 intact:EBI-266172|uniprotkb:A8Y590|uniprotkb:Q7PLT6|uniprotkb:Q8MSB5|uniprotkb:Q8MU87|uniprotkb:Q9W5Q5|uniprotkb:Q9W5S1|ensemblmetazoa:FBpp0112608 psi-mi:o97118_drome(display_long)|uniprotkb:RpL23A(gene name)|psi-mi:RpL23A(display_short)|uniprotkb:rpl23a(gene name synonym)|uniprotkb:CG7977(orf name) psi-mi:parp_drome(display_long)|uniprotkb:Parp(gene name)|psi-mi:Parp(display_short)|uniprotkb:Poly[ADP-ribose] synthase(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase"(gene name synonym)|uniprotkb:Protein ADP-ribosyltransferase Parp(gene name synonym)|uniprotkb:CG40411(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873868 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0026372|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23) refseq:NP_001104452.1|flybase:FBgn0010247|dip:DIP-23413N|ensemblmetazoa:FBgn0010247(gene)|ensemblmetazoa:FBtr0113885(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015030"(Cajal body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0035079"(polytene chromosome puffing)|go:"GO:0035080"(heat shock-mediated polytene chromosome puffing)|go:"GO:0035363"(histone locus body)|go:"GO:0042393"(histone binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045087"(innate immune response)|go:"GO:0051287"(NAD binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061059"(positive regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-DME-110362|reactome:R-DME-2173795|reactome:R-DME-3108214|reactome:R-DME-5685939|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-5696400 pubmed:9931508(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:QdNdZtdqWuBrgbPwXu1RGfGYqvc7227 rogid:SAV/yTZOCz9I+TRMEaZEyYYQ8Kw7227 intact-crc:7D5C9898D3444455|rigid:aWM80euVywXt8YuK/xgUkBMOkmI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P50887 uniprotkb:P35875 intact:EBI-174190|uniprotkb:Q1EC97|uniprotkb:Q9UAN1|uniprotkb:Q9V3X9|ensemblmetazoa:FBpp0070143 intact:EBI-266172|uniprotkb:A8Y590|uniprotkb:Q7PLT6|uniprotkb:Q8MSB5|uniprotkb:Q8MU87|uniprotkb:Q9W5Q5|uniprotkb:Q9W5S1|ensemblmetazoa:FBpp0112608 psi-mi:rl22_drome(display_long)|uniprotkb:RpL22(gene name)|psi-mi:RpL22(display_short)|uniprotkb:CG7434(orf name) psi-mi:parp_drome(display_long)|uniprotkb:Parp(gene name)|psi-mi:Parp(display_short)|uniprotkb:Poly[ADP-ribose] synthase(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase"(gene name synonym)|uniprotkb:Protein ADP-ribosyltransferase Parp(gene name synonym)|uniprotkb:CG40411(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873872 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477134.1|flybase:FBgn0015288|dip:DIP-19124N|ensemblmetazoa:FBgn0015288(gene)|ensemblmetazoa:FBtr0070148(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|rcsb pdb:4V6W|reactome:R-DME-156827|reactome:R-DME-1799339|reactome:R-DME-72689|reactome:R-DME-72706|reactome:R-DME-975956|reactome:R-DME-975957 refseq:NP_001104452.1|flybase:FBgn0010247|dip:DIP-23413N|ensemblmetazoa:FBgn0010247(gene)|ensemblmetazoa:FBtr0113885(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015030"(Cajal body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0035079"(polytene chromosome puffing)|go:"GO:0035080"(heat shock-mediated polytene chromosome puffing)|go:"GO:0035363"(histone locus body)|go:"GO:0042393"(histone binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045087"(innate immune response)|go:"GO:0051287"(NAD binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061059"(positive regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-DME-110362|reactome:R-DME-2173795|reactome:R-DME-3108214|reactome:R-DME-5685939|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-5696400 pubmed:9931508(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:iKbjVVZrZBoy/ffqYWWMNM+w38U7227 rogid:SAV/yTZOCz9I+TRMEaZEyYYQ8Kw7227 intact-crc:EC8540B56F78A998|rigid:Krkne+niSQDfLYM+QpdT9x7OTKA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8MRH0 uniprotkb:O16048 intact:EBI-870453 intact:EBI-870437 psi-mi:q8mrh0_drome(display_long)|uniprotkb:tum(gene name)|psi-mi:tum(display_short)|uniprotkb:CG13345(orf name)|uniprotkb:RacGAP50C(gene name synonym) psi-mi:o16048_drome(display_long)|uniprotkb:pav(gene name)|psi-mi:pav(display_short)|uniprotkb:anon2A12(gene name synonym)|uniprotkb:CG1258(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873876 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0086356|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007525"(somatic muscle development)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0034613"(cellular protein localization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein) flybase:FBgn0011692|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035323"(male germline ring canal)|go:"GO:0035324"(female germline ring canal)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070938"(contractile ring)|go:"GO:0098549"(somatic ring canal)|go:"GO:1903562"(microtubule bundle formation involved in mitotic spindle midzone assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105 pubmed:12530961(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:XQAdJ6MfWNRajLeCYFxvz0YN8B87227 rogid:2wU3z6xEizDo1ftHh1XsS2oTMaY7227 intact-crc:D7526AD144947404|rigid:wY0FuDtSsOFpPgX0QPsmLBYQSN0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P52304 uniprotkb:O16048 intact:EBI-163922|uniprotkb:A4V258|uniprotkb:Q9VWB2|ensemblmetazoa:FBpp0074608|ensemblmetazoa:FBpp0099722 intact:EBI-870437 psi-mi:polo_drome(display_long)|uniprotkb:polo(gene name)|psi-mi:polo(display_short)|uniprotkb:CG12306(orf name) psi-mi:o16048_drome(display_long)|uniprotkb:pav(gene name)|psi-mi:pav(display_short)|uniprotkb:anon2A12(gene name synonym)|uniprotkb:CG1258(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873880 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014592.1|refseq:NP_524179.2|flybase:FBgn0003124|ensemblmetazoa:FBgn0003124(gene)|ensemblmetazoa:FBtr0074839(transcript)|ensemblmetazoa:FBtr0100318(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007058"(spindle assembly involved in female meiosis II)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007147"(female meiosis II)|go:"GO:0007344"(pronuclear fusion)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0030496"(midbody)|go:"GO:0030726"(male germline ring canal formation)|go:"GO:0030954"(astral microtubule nucleation)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035044"(sperm aster formation)|go:"GO:0035046"(pronuclear migration)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0048600"(oocyte fate commitment)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|reactome:R-DME-156711|reactome:R-DME-162658|reactome:R-DME-174178|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-68881|reactome:R-DME-68884|reactome:R-DME-69273|reactome:R-DME-9648025|dip:DIP-18462N flybase:FBgn0011692|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035323"(male germline ring canal)|go:"GO:0035324"(female germline ring canal)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070938"(contractile ring)|go:"GO:0098549"(somatic ring canal)|go:"GO:1903562"(microtubule bundle formation involved in mitotic spindle midzone assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105 pubmed:9585508(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6tWOAy0eGhYWKuTzd50pYRSv62A7227 rogid:2wU3z6xEizDo1ftHh1XsS2oTMaY7227 intact-crc:0CDCD097A07C4646|rigid:/n+7GKasd6bkm/2SHZXSSCecdEo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09077 uniprotkb:P31264 intact:EBI-666569|uniprotkb:Q23990|uniprotkb:Q24508|uniprotkb:Q9V3Q3|ensemblmetazoa:FBpp0081163|ensemblmetazoa:FBpp0089393 intact:EBI-869531|uniprotkb:O97058|uniprotkb:Q9VI44|uniprotkb:Q4JFI5|ensemblmetazoa:FBpp0088333 psi-mi:scr_drome(display_long)|uniprotkb:Scr(gene name)|psi-mi:Scr(display_short)|uniprotkb:CG1030(orf name) psi-mi:hmpb_drome(display_long)|uniprotkb:pb(gene name)|psi-mi:pb(display_short)|uniprotkb:CG31481(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873884 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524248.2|refseq:NP_996165.1|flybase:FBgn0003339|dip:DIP-40017N|ensemblmetazoa:FBgn0003339(gene)|ensemblmetazoa:FBtr0081657(transcript)|ensemblmetazoa:FBtr0081658(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007494"(midgut development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045498"(sex comb development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|rcsb pdb:2R5Y|rcsb pdb:2R5Z refseq:NP_476669.3|refseq:NP_996161.1|refseq:NP_996162.1|refseq:NP_996163.1|flybase:FBgn0051481|ensemblmetazoa:FBgn0051481(gene)|ensemblmetazoa:FBtr0089276(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007381"(specification of segmental identity, labial segment)|go:"GO:0007382"(specification of segmental identity, maxillary segment)|go:"GO:0048728"(proboscis development)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479 pubmed:9362475(see-also)|pubmed:10322642(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:z5Lj6W1yKerSXCkC3CX96vECd507227 rogid:kv0/YsaNKPyeKuzmiDPE33GRS/Q7227 intact-crc:C2EF1B9561D1C005|rigid:9IjQ+PYoaX2rH1xjNuobe0rx7ok false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P48148 uniprotkb:Q8IQ95 intact:EBI-87246|uniprotkb:Q0E958|uniprotkb:Q9V3J0|ensemblmetazoa:FBpp0086353|ensemblmetazoa:FBpp0086354|ensemblmetazoa:FBpp0086355|ensemblmetazoa:FBpp0086356|ensemblmetazoa:FBpp0089129|ensemblmetazoa:FBpp0089130|uniprotkb:A4UZI6 intact:EBI-870464|ensemblmetazoa:FBpp0076489 psi-mi:rho1_drome(display_long)|uniprotkb:Rho1(gene name)|psi-mi:Rho1(display_short)|uniprotkb:CG8416(orf name) psi-mi:q8iq95_drome(display_long)|uniprotkb:pbl(gene name)|psi-mi:pbl(display_short)|uniprotkb:Peb(gene name synonym)|uniprotkb:0083(gene name synonym)|uniprotkb:0293(gene name synonym)|uniprotkb:03(gene name synonym)|uniprotkb:0542(gene name synonym)|uniprotkb:09(gene name synonym)|uniprotkb:20(gene name synonym)|uniprotkb:Dmel\CG8114(gene name synonym)|uniprotkb:ECT2(gene name synonym)|uniprotkb:Ect-2(gene name synonym)|uniprotkb:Ect2(gene name synonym)|uniprotkb:GEF(gene name synonym)|uniprotkb:PBL(gene name synonym)|uniprotkb:Pbl(gene name synonym)|uniprotkb:anon-WO0172774.22(gene name synonym)|uniprotkb:anon-WO0172774.25(gene name synonym)|uniprotkb:"l(3)09645"(gene name synonym)|uniprotkb:Dmel_CG8114(orf name)|uniprotkb:CG8114(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873888 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0014020(gene)|ensemblmetazoa:FBtr0087211(transcript)|ensemblmetazoa:FBtr0087212(transcript)|ensemblmetazoa:FBtr0087213(transcript)|ensemblmetazoa:FBtr0087214(transcript)|ensemblmetazoa:FBtr0087216(transcript)|ensemblmetazoa:FBtr0087217(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007349"(cellularization)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007374"(posterior midgut invagination)|go:"GO:0007377"(germ-band extension)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0005737"(cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0070451"(cell hair)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0110020"(regulation of actomyosin structure organization)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-193634|reactome:R-DME-198203|reactome:R-DME-2173791|reactome:R-DME-350368|reactome:R-DME-350407|reactome:R-DME-350480|reactome:R-DME-392451|reactome:R-DME-3928662|reactome:R-DME-3928663|reactome:R-DME-4086400|interpro:IPR001806(Ras GTPase)|reactome:R-DME-416482|reactome:R-DME-416572|reactome:R-DME-4420097|reactome:R-DME-450728|reactome:R-DME-5625740|reactome:R-DME-5627117|reactome:R-DME-5663220|reactome:R-DME-5666185|reactome:R-DME-5689896|reactome:R-DME-6785631|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-8980692|reactome:R-DME-9013405|reactome:R-DME-9035034|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007601"(visual perception)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035006"(melanization defense response)|go:"GO:0035099"(hemocyte migration)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035298"(regulation of Malpighian tubule size)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0042060"(wound healing)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045179"(apical cortex)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046663"(dorsal closure, leading edge cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0035149"(lumen formation, open tracheal system)|refseq:NP_477098.1|refseq:NP_599135.1|refseq:NP_599136.1|refseq:NP_725524.1|refseq:NP_995849.1|refseq:NP_995850.1|flybase:FBgn0014020|dip:DIP-22676N refseq:NP_729308.1|flybase:FBgn0003041|ensemblmetazoa:FBgn0003041(gene)|ensemblmetazoa:FBtr0076774(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007110"(meiosis I cytokinesis)|go:"GO:0007111"(meiosis II cytokinesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007415"(defasciculation of motor neuron axon)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:2000431"(regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001357(BRCT)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR026817|interpro:IPR035899|interpro:IPR036420 pubmed:10485851(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:DbVx4weiFRCcGfqdsUQWqWQc0Q47227 rogid:LTGuzZgwNFwAZxYxEXU6qMvzL0Y7227 intact-crc:E43105B6B79651D4|rigid:FGBs1Mjoi09YjFWrD/xc2yTyJUA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8MRH0 uniprotkb:Q8IQ95 intact:EBI-870453 intact:EBI-870464|ensemblmetazoa:FBpp0076489 psi-mi:q8mrh0_drome(display_long)|uniprotkb:tum(gene name)|psi-mi:tum(display_short)|uniprotkb:CG13345(orf name)|uniprotkb:RacGAP50C(gene name synonym) psi-mi:q8iq95_drome(display_long)|uniprotkb:pbl(gene name)|psi-mi:pbl(display_short)|uniprotkb:Peb(gene name synonym)|uniprotkb:0083(gene name synonym)|uniprotkb:0293(gene name synonym)|uniprotkb:03(gene name synonym)|uniprotkb:0542(gene name synonym)|uniprotkb:09(gene name synonym)|uniprotkb:20(gene name synonym)|uniprotkb:Dmel\CG8114(gene name synonym)|uniprotkb:ECT2(gene name synonym)|uniprotkb:Ect-2(gene name synonym)|uniprotkb:Ect2(gene name synonym)|uniprotkb:GEF(gene name synonym)|uniprotkb:PBL(gene name synonym)|uniprotkb:Pbl(gene name synonym)|uniprotkb:anon-WO0172774.22(gene name synonym)|uniprotkb:anon-WO0172774.25(gene name synonym)|uniprotkb:"l(3)09645"(gene name synonym)|uniprotkb:Dmel_CG8114(orf name)|uniprotkb:CG8114(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873892 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0086356|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007525"(somatic muscle development)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0034613"(cellular protein localization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein) refseq:NP_729308.1|flybase:FBgn0003041|ensemblmetazoa:FBgn0003041(gene)|ensemblmetazoa:FBtr0076774(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007110"(meiosis I cytokinesis)|go:"GO:0007111"(meiosis II cytokinesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007415"(defasciculation of motor neuron axon)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:2000431"(regulation of cytokinesis, actomyosin contractile ring assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001357(BRCT)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR026817|interpro:IPR035899|interpro:IPR036420 pubmed:12530961(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:XQAdJ6MfWNRajLeCYFxvz0YN8B87227 rogid:LTGuzZgwNFwAZxYxEXU6qMvzL0Y7227 intact-crc:C77BB3F8E7AD2EF9|rigid:H6RtBifKOOSKAKYfZMp/ISlQB5c false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20227 uniprotkb:P26017 intact:EBI-169179|uniprotkb:Q9W2D8|ensemblmetazoa:FBpp0071596 intact:EBI-177152|uniprotkb:Q9VP49|ensemblmetazoa:FBpp0078059 psi-mi:tbp_drome(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:CG9874(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:pc_drome(display_long)|uniprotkb:Pc(gene name)|psi-mi:Pc(display_short)|uniprotkb:CG7618(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873896 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523805.1|flybase:FBgn0003687|ensemblmetazoa:FBgn0003687(gene)|ensemblmetazoa:FBtr0071679(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519|dip:DIP-80N refseq:NP_524199.1|flybase:FBgn0003042|ensemblmetazoa:FBgn0003042(gene)|ensemblmetazoa:FBtr0078405(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007385"(specification of segmental identity, abdomen)|go:"GO:0007419"(ventral cord development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0022008"(neurogenesis)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042060"(wound healing)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|rcsb pdb:1PDQ|rcsb pdb:1PFB|reactome:R-DME-3108214|reactome:R-DME-3899300|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724 pubmed:11493925(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:eRlX8luNoF4M7SFmEnxKSbI6FJo7227 rogid:EoeY3ywjOXNZO7fubeNPow+WW4w7227 intact-crc:9457629C2F38231A|rigid:9IIEUE7up0QTVfOKCoxiKEXgHpw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P47825 uniprotkb:P26017 intact:EBI-277958|uniprotkb:P49845|uniprotkb:Q0E8E3|uniprotkb:Q1LZ31|uniprotkb:Q8T9E0|uniprotkb:Q9VUY7|ensemblmetazoa:FBpp0075205|ensemblmetazoa:FBpp0075206|ensemblmetazoa:FBpp0291125|ensemblmetazoa:FBpp0311865 intact:EBI-177152|uniprotkb:Q9VP49|ensemblmetazoa:FBpp0078059 psi-mi:taf4_drome(display_long)|uniprotkb:Transcription initiation factor TFIID 110 kDa subunit(gene name synonym)|uniprotkb:110 kDa TBP-associated factor(gene name synonym)|uniprotkb:Taf4(gene name)|psi-mi:Taf4(display_short)|uniprotkb:TAF110(gene name synonym)|uniprotkb:CG5444(orf name) psi-mi:pc_drome(display_long)|uniprotkb:Pc(gene name)|psi-mi:Pc(display_short)|uniprotkb:CG7618(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873900 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_788511.1|refseq:NP_996101.1|flybase:FBgn0010280|refseq:NP_001287077.1|refseq:NP_001163453.1|refseq:NP_524102.1|refseq:NP_730109.1|dip:DIP-237N|ensemblmetazoa:FBgn0010280(gene)|ensemblmetazoa:FBtr0075448(transcript)|ensemblmetazoa:FBtr0075449(transcript)|ensemblmetazoa:FBtr0301911(transcript)|ensemblmetazoa:FBtr0345951(transcript)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR007900(Transcription initiation factor TFIID component TAF4)|interpro:IPR009072(Histone-fold)|interpro:IPR037249|mint:P47825|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 refseq:NP_524199.1|flybase:FBgn0003042|ensemblmetazoa:FBgn0003042(gene)|ensemblmetazoa:FBtr0078405(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007385"(specification of segmental identity, abdomen)|go:"GO:0007419"(ventral cord development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0022008"(neurogenesis)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042060"(wound healing)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|rcsb pdb:1PDQ|rcsb pdb:1PFB|reactome:R-DME-3108214|reactome:R-DME-3899300|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724 pubmed:11493925(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KMwgcLywcp/YxxTLBjtmqXNPhdo7227 rogid:EoeY3ywjOXNZO7fubeNPow+WW4w7227 intact-crc:E3374E3B6F376F23|rigid:0vo7dqTwlx0dJN+jlA3dH11Jfk0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P35820 uniprotkb:P26017 intact:EBI-84600|uniprotkb:Q9V6I9|ensemblmetazoa:FBpp0086911|ensemblmetazoa:FBpp0311395|ensemblmetazoa:FBpp0311526 intact:EBI-177152|uniprotkb:Q9VP49|ensemblmetazoa:FBpp0078059 psi-mi:psc_drome(display_long)|uniprotkb:Psc(gene name)|psi-mi:Psc(display_short)|uniprotkb:Protein posterior sex combs(gene name synonym)|uniprotkb:CG3886(orf name) psi-mi:pc_drome(display_long)|uniprotkb:Pc(gene name)|psi-mi:Pc(display_short)|uniprotkb:CG7618(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873904 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523725.2|flybase:FBgn0005624|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0007419"(ventral cord development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-DME-3108214|reactome:R-DME-3899300|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724|reactome:R-DME-8953750|interpro:IPR001841(Zinc finger, RING-type)|ensemblmetazoa:FBgn0005624(gene)|ensemblmetazoa:FBtr0087798(transcript)|ensemblmetazoa:FBtr0345196(transcript)|ensemblmetazoa:FBtr0345375(transcript)|refseq:NP_001286368.1|refseq:NP_001286369.1 refseq:NP_524199.1|flybase:FBgn0003042|ensemblmetazoa:FBgn0003042(gene)|ensemblmetazoa:FBtr0078405(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007385"(specification of segmental identity, abdomen)|go:"GO:0007419"(ventral cord development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0022008"(neurogenesis)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042060"(wound healing)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|rcsb pdb:1PDQ|rcsb pdb:1PFB|reactome:R-DME-3108214|reactome:R-DME-3899300|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724 pubmed:8601334(see-also)|pubmed:9566890(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:C0LCX+uqZs0r5z4fFql91xQXLNs7227 rogid:EoeY3ywjOXNZO7fubeNPow+WW4w7227 intact-crc:4B1AF919E7F6AED2|rigid:uUpMp/QbKHt52yo3dIyxi9toKhI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P49021 uniprotkb:P07663 intact:EBI-266295|uniprotkb:O44380|uniprotkb:Q8I037|uniprotkb:Q95U67|uniprotkb:Q9VQR6|uniprotkb:Q9VQR7|intact:EBI-3407510|uniprotkb:M9MRE9|uniprotkb:A4V040|uniprotkb:B7Z007|uniprotkb:B7Z008|uniprotkb:C9QPB7|uniprotkb:Q1WWF5|uniprotkb:Q59E16|intact:EBI-9944820|ensemblmetazoa:FBpp0077256|ensemblmetazoa:FBpp0305454 intact:EBI-496170|uniprotkb:O17483|uniprotkb:O76882|uniprotkb:O76883|uniprotkb:O76884|uniprotkb:O76885|uniprotkb:Q24446|uniprotkb:Q24447|uniprotkb:Q24448|uniprotkb:Q24449|uniprotkb:Q6PVA3|uniprotkb:Q8MLY0|uniprotkb:Q9GN20|uniprotkb:Q9GN51|uniprotkb:Q9GQH9|uniprotkb:Q9GV48|uniprotkb:Q9GV53|uniprotkb:Q9GV54|uniprotkb:Q9GV55|uniprotkb:Q9W4X0|ensemblmetazoa:FBpp0070455 psi-mi:tim_drome(display_long)|uniprotkb:tim(gene name)|psi-mi:tim(display_short)|uniprotkb:CG3234(orf name) psi-mi:per_drome(display_long)|uniprotkb:Protein clock-6(gene name synonym)|uniprotkb:per(gene name)|psi-mi:per(display_short)|uniprotkb:CG2647(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873908 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_722914.3|flybase:FBgn0014396|refseq:NP_722912.3|refseq:NP_722913.3|refseq:NP_001014463.2|refseq:NP_001033872.2|refseq:NP_001137780.2|refseq:NP_001137781.2|refseq:NP_001188686.2|dip:DIP-29425N|ensemblmetazoa:FBgn0014396(gene)|ensemblmetazoa:FBtr0077567(transcript)|ensemblmetazoa:FBtr0333256(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003053"(circadian regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007617"(mating behavior)|go:"GO:0007620"(copulation)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009648"(photoperiodism)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0043111"(replication fork arrest)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0046957"(negative phototaxis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048478"(replication fork protection)|go:"GO:0048512"(circadian behavior)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR006906(Timeless protein)|interpro:IPR007725(Timeless C-terminal)|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 refseq:NP_525056.2|flybase:FBgn0003068|refseq:NP_001259194.1|dip:DIP-29426N|ensemblmetazoa:FBgn0003068(gene)|ensemblmetazoa:FBtr0070477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001306"(age-dependent response to oxidative stress)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007616"(long-term memory)|go:"GO:0007617"(mating behavior)|go:"GO:0007619"(courtship behavior)|go:"GO:0007620"(copulation)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0044297"(cell body)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0048512"(circadian behavior)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR035965|rcsb pdb:1WA9|rcsb pdb:3GEC|rcsb pdb:3RTY|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432524|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 pubmed:7481773(see-also)|pubmed:8596938(see-also)|pubmed:8600384(see-also)|pubmed:8938123(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:wdN/j17nXo6XpfHUGGSo5zYNhog7227 rogid:+l/mg+2MJForY5dORYWnWsVAhNI7227 intact-crc:B038588685548C01|rigid:4hLgVCMEaTQhXE4T78/fOymf/Mk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P07663 uniprotkb:P07663 intact:EBI-496170|uniprotkb:O17483|uniprotkb:O76882|uniprotkb:O76883|uniprotkb:O76884|uniprotkb:O76885|uniprotkb:Q24446|uniprotkb:Q24447|uniprotkb:Q24448|uniprotkb:Q24449|uniprotkb:Q6PVA3|uniprotkb:Q8MLY0|uniprotkb:Q9GN20|uniprotkb:Q9GN51|uniprotkb:Q9GQH9|uniprotkb:Q9GV48|uniprotkb:Q9GV53|uniprotkb:Q9GV54|uniprotkb:Q9GV55|uniprotkb:Q9W4X0|ensemblmetazoa:FBpp0070455 intact:EBI-496170|uniprotkb:O17483|uniprotkb:O76882|uniprotkb:O76883|uniprotkb:O76884|uniprotkb:O76885|uniprotkb:Q24446|uniprotkb:Q24447|uniprotkb:Q24448|uniprotkb:Q24449|uniprotkb:Q6PVA3|uniprotkb:Q8MLY0|uniprotkb:Q9GN20|uniprotkb:Q9GN51|uniprotkb:Q9GQH9|uniprotkb:Q9GV48|uniprotkb:Q9GV53|uniprotkb:Q9GV54|uniprotkb:Q9GV55|uniprotkb:Q9W4X0|ensemblmetazoa:FBpp0070455 psi-mi:per_drome(display_long)|uniprotkb:Protein clock-6(gene name synonym)|uniprotkb:per(gene name)|psi-mi:per(display_short)|uniprotkb:CG2647(orf name) psi-mi:per_drome(display_long)|uniprotkb:Protein clock-6(gene name synonym)|uniprotkb:per(gene name)|psi-mi:per(display_short)|uniprotkb:CG2647(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873912 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_525056.2|flybase:FBgn0003068|refseq:NP_001259194.1|dip:DIP-29426N|ensemblmetazoa:FBgn0003068(gene)|ensemblmetazoa:FBtr0070477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001306"(age-dependent response to oxidative stress)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007616"(long-term memory)|go:"GO:0007617"(mating behavior)|go:"GO:0007619"(courtship behavior)|go:"GO:0007620"(copulation)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0044297"(cell body)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0048512"(circadian behavior)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR035965|rcsb pdb:1WA9|rcsb pdb:3GEC|rcsb pdb:3RTY|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432524|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 refseq:NP_525056.2|flybase:FBgn0003068|refseq:NP_001259194.1|dip:DIP-29426N|ensemblmetazoa:FBgn0003068(gene)|ensemblmetazoa:FBtr0070477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001306"(age-dependent response to oxidative stress)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007616"(long-term memory)|go:"GO:0007617"(mating behavior)|go:"GO:0007619"(courtship behavior)|go:"GO:0007620"(copulation)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0044297"(cell body)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0048512"(circadian behavior)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR035965|rcsb pdb:1WA9|rcsb pdb:3GEC|rcsb pdb:3RTY|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432524|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 pubmed:7855598(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+l/mg+2MJForY5dORYWnWsVAhNI7227 rogid:+l/mg+2MJForY5dORYWnWsVAhNI7227 intact-crc:148EC00D4D9E9072|rigid:DPNtC7q1wPX4Tmk2fzlPMAU9hqA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20227 uniprotkb:Q9NF31 intact:EBI-169179|uniprotkb:Q9W2D8|ensemblmetazoa:FBpp0071596 intact:EBI-870485|ensemblmetazoa:FBpp0111756 psi-mi:tbp_drome(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:CG9874(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:q9nf31_drome(display_long)|uniprotkb:ph-d(gene name)|psi-mi:ph-d(display_short)|uniprotkb:"EG:BACN25G24.3"(gene name synonym)|uniprotkb:DROZFP(gene name synonym)|uniprotkb:Dmel\CG3895(gene name synonym)|uniprotkb:PH(gene name synonym)|uniprotkb:PH-d(gene name synonym)|uniprotkb:PHD(gene name synonym)|uniprotkb:Ph(gene name synonym)|uniprotkb:Ph-d(gene name synonym)|uniprotkb:PhD(gene name synonym)|uniprotkb:ph(gene name synonym)|uniprotkb:ph-D(gene name synonym)|uniprotkb:ph[D](gene name synonym)|uniprotkb:ph[d](gene name synonym)|uniprotkb:phd(gene name synonym)|uniprotkb:phm(gene name synonym)|uniprotkb:Dmel_CG3895(orf name)|uniprotkb:CG3895(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873916 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523805.1|flybase:FBgn0003687|ensemblmetazoa:FBgn0003687(gene)|ensemblmetazoa:FBtr0071679(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519|dip:DIP-80N refseq:NP_001096865.1|flybase:FBgn0004860|ensemblmetazoa:FBgn0004860(gene)|ensemblmetazoa:FBtr0112843(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051087"(chaperone binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603 pubmed:11493925(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:eRlX8luNoF4M7SFmEnxKSbI6FJo7227 rogid:gMjadZpFiVmDDlp05CVRA7U7bYQ7227 intact-crc:92950C9E15D26718|rigid:PQ2YaPrebmizAae9qjHp1J4wQ9c false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P47825 uniprotkb:Q9NF31 intact:EBI-277958|uniprotkb:P49845|uniprotkb:Q0E8E3|uniprotkb:Q1LZ31|uniprotkb:Q8T9E0|uniprotkb:Q9VUY7|ensemblmetazoa:FBpp0075205|ensemblmetazoa:FBpp0075206|ensemblmetazoa:FBpp0291125|ensemblmetazoa:FBpp0311865 intact:EBI-870485|ensemblmetazoa:FBpp0111756 psi-mi:taf4_drome(display_long)|uniprotkb:Transcription initiation factor TFIID 110 kDa subunit(gene name synonym)|uniprotkb:110 kDa TBP-associated factor(gene name synonym)|uniprotkb:Taf4(gene name)|psi-mi:Taf4(display_short)|uniprotkb:TAF110(gene name synonym)|uniprotkb:CG5444(orf name) psi-mi:q9nf31_drome(display_long)|uniprotkb:ph-d(gene name)|psi-mi:ph-d(display_short)|uniprotkb:"EG:BACN25G24.3"(gene name synonym)|uniprotkb:DROZFP(gene name synonym)|uniprotkb:Dmel\CG3895(gene name synonym)|uniprotkb:PH(gene name synonym)|uniprotkb:PH-d(gene name synonym)|uniprotkb:PHD(gene name synonym)|uniprotkb:Ph(gene name synonym)|uniprotkb:Ph-d(gene name synonym)|uniprotkb:PhD(gene name synonym)|uniprotkb:ph(gene name synonym)|uniprotkb:ph-D(gene name synonym)|uniprotkb:ph[D](gene name synonym)|uniprotkb:ph[d](gene name synonym)|uniprotkb:phd(gene name synonym)|uniprotkb:phm(gene name synonym)|uniprotkb:Dmel_CG3895(orf name)|uniprotkb:CG3895(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873920 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_788511.1|refseq:NP_996101.1|flybase:FBgn0010280|refseq:NP_001287077.1|refseq:NP_001163453.1|refseq:NP_524102.1|refseq:NP_730109.1|dip:DIP-237N|ensemblmetazoa:FBgn0010280(gene)|ensemblmetazoa:FBtr0075448(transcript)|ensemblmetazoa:FBtr0075449(transcript)|ensemblmetazoa:FBtr0301911(transcript)|ensemblmetazoa:FBtr0345951(transcript)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR007900(Transcription initiation factor TFIID component TAF4)|interpro:IPR009072(Histone-fold)|interpro:IPR037249|mint:P47825|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 refseq:NP_001096865.1|flybase:FBgn0004860|ensemblmetazoa:FBgn0004860(gene)|ensemblmetazoa:FBtr0112843(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051087"(chaperone binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603 pubmed:11493925(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KMwgcLywcp/YxxTLBjtmqXNPhdo7227 rogid:gMjadZpFiVmDDlp05CVRA7U7bYQ7227 intact-crc:6862BE65D4E146D0|rigid:EkeSYfkKwJKPTMxk7J68qW3TmDw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VHA0 uniprotkb:Q9NF31 intact:EBI-89256|uniprotkb:Q24191|ensemblmetazoa:FBpp0081580|ensemblmetazoa:FBpp0297150 intact:EBI-870485|ensemblmetazoa:FBpp0111756 psi-mi:scm_drome(display_long)|uniprotkb:Scm(gene name)|psi-mi:Scm(display_short)|uniprotkb:CG9495(orf name)|uniprotkb:Sex comb on midleg protein(gene name synonym) psi-mi:q9nf31_drome(display_long)|uniprotkb:ph-d(gene name)|psi-mi:ph-d(display_short)|uniprotkb:"EG:BACN25G24.3"(gene name synonym)|uniprotkb:DROZFP(gene name synonym)|uniprotkb:Dmel\CG3895(gene name synonym)|uniprotkb:PH(gene name synonym)|uniprotkb:PH-d(gene name synonym)|uniprotkb:PHD(gene name synonym)|uniprotkb:Ph(gene name synonym)|uniprotkb:Ph-d(gene name synonym)|uniprotkb:PhD(gene name synonym)|uniprotkb:ph(gene name synonym)|uniprotkb:ph-D(gene name synonym)|uniprotkb:ph[D](gene name synonym)|uniprotkb:ph[d](gene name synonym)|uniprotkb:phd(gene name synonym)|uniprotkb:phm(gene name synonym)|uniprotkb:Dmel_CG3895(orf name)|uniprotkb:CG3895(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873924 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_731385.1|flybase:FBgn0003334|ensemblmetazoa:FBgn0003334(gene)|ensemblmetazoa:FBtr0082102(transcript)|ensemblmetazoa:FBtr0306008(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007419"(ventral cord development)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0022008"(neurogenesis)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0048749"(compound eye development)|go:"GO:0140259"(PRC1 complex binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR012313(Zinc finger, FCS-type)|go:"GO:0008270"(zinc ion binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR038348|mint:Q9VHA0|rcsb pdb:1PK1|rcsb pdb:1PK3|rcsb pdb:2R57|rcsb pdb:2R58|rcsb pdb:2R5A|rcsb pdb:2R5M|rcsb pdb:5J8Y|reactome:R-DME-3899300|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724|reactome:R-DME-3108214|refseq:NP_001247006.1|dip:DIP-17570N refseq:NP_001096865.1|flybase:FBgn0004860|ensemblmetazoa:FBgn0004860(gene)|ensemblmetazoa:FBtr0112843(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051087"(chaperone binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603 pubmed:9499582(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6dlycV4Snf+YiEqKnJQEmicO9Zw7227 rogid:gMjadZpFiVmDDlp05CVRA7U7bYQ7227 intact-crc:AC376BE4DB0811EA|rigid:DIIR9JncS0JVnN2dyDpnoQC8Vkk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P35820 uniprotkb:Q9NF31 intact:EBI-84600|uniprotkb:Q9V6I9|ensemblmetazoa:FBpp0086911|ensemblmetazoa:FBpp0311395|ensemblmetazoa:FBpp0311526 intact:EBI-870485|ensemblmetazoa:FBpp0111756 psi-mi:psc_drome(display_long)|uniprotkb:Psc(gene name)|psi-mi:Psc(display_short)|uniprotkb:Protein posterior sex combs(gene name synonym)|uniprotkb:CG3886(orf name) psi-mi:q9nf31_drome(display_long)|uniprotkb:ph-d(gene name)|psi-mi:ph-d(display_short)|uniprotkb:"EG:BACN25G24.3"(gene name synonym)|uniprotkb:DROZFP(gene name synonym)|uniprotkb:Dmel\CG3895(gene name synonym)|uniprotkb:PH(gene name synonym)|uniprotkb:PH-d(gene name synonym)|uniprotkb:PHD(gene name synonym)|uniprotkb:Ph(gene name synonym)|uniprotkb:Ph-d(gene name synonym)|uniprotkb:PhD(gene name synonym)|uniprotkb:ph(gene name synonym)|uniprotkb:ph-D(gene name synonym)|uniprotkb:ph[D](gene name synonym)|uniprotkb:ph[d](gene name synonym)|uniprotkb:phd(gene name synonym)|uniprotkb:phm(gene name synonym)|uniprotkb:Dmel_CG3895(orf name)|uniprotkb:CG3895(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873928 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523725.2|flybase:FBgn0005624|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0007419"(ventral cord development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-DME-3108214|reactome:R-DME-3899300|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724|reactome:R-DME-8953750|interpro:IPR001841(Zinc finger, RING-type)|ensemblmetazoa:FBgn0005624(gene)|ensemblmetazoa:FBtr0087798(transcript)|ensemblmetazoa:FBtr0345196(transcript)|ensemblmetazoa:FBtr0345375(transcript)|refseq:NP_001286368.1|refseq:NP_001286369.1 refseq:NP_001096865.1|flybase:FBgn0004860|ensemblmetazoa:FBgn0004860(gene)|ensemblmetazoa:FBtr0112843(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051087"(chaperone binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603 pubmed:9566890(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:C0LCX+uqZs0r5z4fFql91xQXLNs7227 rogid:gMjadZpFiVmDDlp05CVRA7U7bYQ7227 intact-crc:8151A8BA99882DC9|rigid:xzxLKJvRUcpdPl0LvnRjlxfqtYA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18475 uniprotkb:P11346 intact:EBI-195402|uniprotkb:A8DY54|uniprotkb:A8DY56|uniprotkb:Q9V4R2|ensemblmetazoa:FBpp0088012 intact:EBI-664624|uniprotkb:Q9W4Z3|uniprotkb:Q8I086|uniprotkb:Q8I0D9|uniprotkb:Q8ISE1|uniprotkb:Q8ISE2|uniprotkb:Q8ISE3|uniprotkb:Q9NEH9|uniprotkb:A8JUV5|uniprotkb:Q0KHW7|ensemblmetazoa:FBpp0070385|ensemblmetazoa:FBpp0310458 psi-mi:torso_drome(display_long)|uniprotkb:tor(gene name)|psi-mi:tor(display_short)|uniprotkb:CG1389(orf name) psi-mi:kraf1_drome(display_long)|uniprotkb:Raf(gene name)|psi-mi:Raf(display_short)|uniprotkb:Protein pole-hole(gene name synonym)|uniprotkb:ph(gene name synonym)|uniprotkb:phl(gene name synonym)|uniprotkb:CG2845(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873932 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097212.2|refseq:NP_476762.1|flybase:FBgn0003733|ensemblmetazoa:FBgn0003733(gene)|ensemblmetazoa:FBtr0088938(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007278"(pole cell fate determination)|go:"GO:0007280"(pole cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0046957"(negative phototaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116 refseq:NP_525047.1|flybase:FBgn0003079|refseq:NP_001096867.3|dip:DIP-29769N|ensemblmetazoa:FBgn0003079(gene)|ensemblmetazoa:FBtr0070401(transcript)|ensemblmetazoa:FBtr0344007(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0002168"(instar larval development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007552"(metamorphosis)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042386"(hemocyte differentiation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029071|reactome:R-DME-1295596|reactome:R-DME-170968|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-432553|reactome:R-DME-5621575|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5675482 pubmed:7720074(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xto08nbumwFlew52tyO4IgeMEqs7227 rogid:rbvsd7+5RvYrFoXyonEM6Li84hM7227 intact-crc:194DB8D3265BDEC7|rigid:LGzZKxfXdd7kjgVHiOSmBnvjO8I false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08646 uniprotkb:P11346 intact:EBI-119517|uniprotkb:Q9V448|ensemblmetazoa:FBpp0081600 intact:EBI-664624|uniprotkb:Q9W4Z3|uniprotkb:Q8I086|uniprotkb:Q8I0D9|uniprotkb:Q8ISE1|uniprotkb:Q8ISE2|uniprotkb:Q8ISE3|uniprotkb:Q9NEH9|uniprotkb:A8JUV5|uniprotkb:Q0KHW7|ensemblmetazoa:FBpp0070385|ensemblmetazoa:FBpp0310458 psi-mi:ras1_drome(display_long)|uniprotkb:Ras85D(gene name)|psi-mi:Ras85D(display_short)|uniprotkb:Ras1(gene name synonym)|uniprotkb:CG9375(orf name)|uniprotkb:Dmras85D(gene name synonym) psi-mi:kraf1_drome(display_long)|uniprotkb:Raf(gene name)|psi-mi:Raf(display_short)|uniprotkb:Protein pole-hole(gene name synonym)|uniprotkb:ph(gene name synonym)|uniprotkb:phl(gene name synonym)|uniprotkb:CG2845(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873936 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476699.1|flybase:FBgn0003205|ensemblmetazoa:FBgn0003205(gene)|ensemblmetazoa:FBtr0082122(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0001709"(cell fate determination)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0002168"(instar larval development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0019003"(GDP binding)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0000165"(MAPK cascade)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0040008"(regulation of growth)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0051607"(defense response to virus)|go:"GO:0060438"(trachea development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072002"(Malpighian tubule development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-DME-1250347|reactome:R-DME-1433557|reactome:R-DME-171007|reactome:R-DME-179812|reactome:R-DME-180336|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2871796|reactome:R-DME-375165|reactome:R-DME-3928662|reactome:R-DME-4086398|reactome:R-DME-432553|reactome:R-DME-5218921|reactome:R-DME-5621575|reactome:R-DME-5654688|reactome:R-DME-5654693|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5673000|reactome:R-DME-5673001|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-8951936|reactome:R-DME-9607240|reactome:R-DME-9634635|reactome:R-DME-9648002|dip:DIP-23541N refseq:NP_525047.1|flybase:FBgn0003079|refseq:NP_001096867.3|dip:DIP-29769N|ensemblmetazoa:FBgn0003079(gene)|ensemblmetazoa:FBtr0070401(transcript)|ensemblmetazoa:FBtr0344007(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0002168"(instar larval development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007552"(metamorphosis)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042386"(hemocyte differentiation)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029071|reactome:R-DME-1295596|reactome:R-DME-170968|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-432553|reactome:R-DME-5621575|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5675482 pubmed:1461284(see-also)|pubmed:8458578(see-also)|pubmed:8722784(see-also)|pubmed:9389658(see-also)|pubmed:9811584(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+9A4GDDFmYKN5famfgTGA+t/y+Y7227 rogid:rbvsd7+5RvYrFoXyonEM6Li84hM7227 intact-crc:2A29FEF63D83CDCD|rigid:iduKQ07A33yKAON2vtblMLXIPF8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P15348 uniprotkb:P39769 intact:EBI-134105|uniprotkb:Q9VIW2|uniprotkb:Q6NR40|uniprotkb:M9PDQ1|ensemblmetazoa:FBpp0080825|ensemblmetazoa:FBpp0304598 intact:EBI-300360|uniprotkb:O46097|uniprotkb:Q9W521|uniprotkb:Q9W522|ensemblmetazoa:FBpp0070416 psi-mi:top2_drome(display_long)|uniprotkb:Top2(gene name)|psi-mi:Top2(display_short)|uniprotkb:CG10223(orf name)|uniprotkb:DNA topoisomerase II(gene name synonym) psi-mi:php_drome(display_long)|uniprotkb:CG18412(orf name)|uniprotkb:ph-p(gene name)|psi-mi:ph-p(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873940 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0284220|refseq:NP_476760.1|refseq:NP_001260580.1|ensemblmetazoa:FBgn0284220(gene)|ensemblmetazoa:FBtr0081287(transcript)|ensemblmetazoa:FBtr0332320(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006342"|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008623"(CHRAC)|go:"GO:0030261"(chromosome condensation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|interpro:IPR020568|interpro:IPR031660|interpro:IPR034157|interpro:IPR036890|reactome:R-DME-4615885 ensemblmetazoa:FBgn0004861(gene)|ensemblmetazoa:FBtr0070432(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051087"(chaperone binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P39769|rcsb pdb:1KW4|rcsb pdb:1PK1|reactome:R-DME-3108214|reactome:R-DME-3899300|go:"GO:0030713"(ovarian follicle cell stalk formation)|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724|reactome:R-DME-8953750|refseq:NP_476871.2|flybase:FBgn0004861|dip:DIP-19426N pubmed:11172718(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:EkijDVP5cT0HlKzmQhXsNTYxwms7227 rogid:3pxds6HiNRg2p/Vcl7hFNcPInFI7227 intact-crc:7C772D6E823B1BA8|rigid:kxHTEM97ZpUcOo/PhzyFpBESpV8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20227 uniprotkb:P39769 intact:EBI-169179|uniprotkb:Q9W2D8|ensemblmetazoa:FBpp0071596 intact:EBI-300360|uniprotkb:O46097|uniprotkb:Q9W521|uniprotkb:Q9W522|ensemblmetazoa:FBpp0070416 psi-mi:tbp_drome(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:CG9874(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:php_drome(display_long)|uniprotkb:CG18412(orf name)|uniprotkb:ph-p(gene name)|psi-mi:ph-p(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873944 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523805.1|flybase:FBgn0003687|ensemblmetazoa:FBgn0003687(gene)|ensemblmetazoa:FBtr0071679(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519|dip:DIP-80N ensemblmetazoa:FBgn0004861(gene)|ensemblmetazoa:FBtr0070432(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051087"(chaperone binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P39769|rcsb pdb:1KW4|rcsb pdb:1PK1|reactome:R-DME-3108214|reactome:R-DME-3899300|go:"GO:0030713"(ovarian follicle cell stalk formation)|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724|reactome:R-DME-8953750|refseq:NP_476871.2|flybase:FBgn0004861|dip:DIP-19426N pubmed:11493925(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:eRlX8luNoF4M7SFmEnxKSbI6FJo7227 rogid:3pxds6HiNRg2p/Vcl7hFNcPInFI7227 intact-crc:8FE0CD4214C3B4B7|rigid:TM4FypuHlstxoGb6koEko/9eMCw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P47825 uniprotkb:P39769 intact:EBI-277958|uniprotkb:P49845|uniprotkb:Q0E8E3|uniprotkb:Q1LZ31|uniprotkb:Q8T9E0|uniprotkb:Q9VUY7|ensemblmetazoa:FBpp0075205|ensemblmetazoa:FBpp0075206|ensemblmetazoa:FBpp0291125|ensemblmetazoa:FBpp0311865 intact:EBI-300360|uniprotkb:O46097|uniprotkb:Q9W521|uniprotkb:Q9W522|ensemblmetazoa:FBpp0070416 psi-mi:taf4_drome(display_long)|uniprotkb:Transcription initiation factor TFIID 110 kDa subunit(gene name synonym)|uniprotkb:110 kDa TBP-associated factor(gene name synonym)|uniprotkb:Taf4(gene name)|psi-mi:Taf4(display_short)|uniprotkb:TAF110(gene name synonym)|uniprotkb:CG5444(orf name) psi-mi:php_drome(display_long)|uniprotkb:CG18412(orf name)|uniprotkb:ph-p(gene name)|psi-mi:ph-p(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873948 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_788511.1|refseq:NP_996101.1|flybase:FBgn0010280|refseq:NP_001287077.1|refseq:NP_001163453.1|refseq:NP_524102.1|refseq:NP_730109.1|dip:DIP-237N|ensemblmetazoa:FBgn0010280(gene)|ensemblmetazoa:FBtr0075448(transcript)|ensemblmetazoa:FBtr0075449(transcript)|ensemblmetazoa:FBtr0301911(transcript)|ensemblmetazoa:FBtr0345951(transcript)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR007900(Transcription initiation factor TFIID component TAF4)|interpro:IPR009072(Histone-fold)|interpro:IPR037249|mint:P47825|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 ensemblmetazoa:FBgn0004861(gene)|ensemblmetazoa:FBtr0070432(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051087"(chaperone binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P39769|rcsb pdb:1KW4|rcsb pdb:1PK1|reactome:R-DME-3108214|reactome:R-DME-3899300|go:"GO:0030713"(ovarian follicle cell stalk formation)|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724|reactome:R-DME-8953750|refseq:NP_476871.2|flybase:FBgn0004861|dip:DIP-19426N pubmed:11493925(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KMwgcLywcp/YxxTLBjtmqXNPhdo7227 rogid:3pxds6HiNRg2p/Vcl7hFNcPInFI7227 intact-crc:69A26289C3E6465D|rigid:qiyqhF+N61Hdp5rZB6cXmhlDwFE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VHA0 uniprotkb:P39769 intact:EBI-89256|uniprotkb:Q24191|ensemblmetazoa:FBpp0081580|ensemblmetazoa:FBpp0297150 intact:EBI-300360|uniprotkb:O46097|uniprotkb:Q9W521|uniprotkb:Q9W522|ensemblmetazoa:FBpp0070416 psi-mi:scm_drome(display_long)|uniprotkb:Scm(gene name)|psi-mi:Scm(display_short)|uniprotkb:CG9495(orf name)|uniprotkb:Sex comb on midleg protein(gene name synonym) psi-mi:php_drome(display_long)|uniprotkb:CG18412(orf name)|uniprotkb:ph-p(gene name)|psi-mi:ph-p(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873952 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_731385.1|flybase:FBgn0003334|ensemblmetazoa:FBgn0003334(gene)|ensemblmetazoa:FBtr0082102(transcript)|ensemblmetazoa:FBtr0306008(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007419"(ventral cord development)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0022008"(neurogenesis)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0048749"(compound eye development)|go:"GO:0140259"(PRC1 complex binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR012313(Zinc finger, FCS-type)|go:"GO:0008270"(zinc ion binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR038348|mint:Q9VHA0|rcsb pdb:1PK1|rcsb pdb:1PK3|rcsb pdb:2R57|rcsb pdb:2R58|rcsb pdb:2R5A|rcsb pdb:2R5M|rcsb pdb:5J8Y|reactome:R-DME-3899300|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724|reactome:R-DME-3108214|refseq:NP_001247006.1|dip:DIP-17570N ensemblmetazoa:FBgn0004861(gene)|ensemblmetazoa:FBtr0070432(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051087"(chaperone binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P39769|rcsb pdb:1KW4|rcsb pdb:1PK1|reactome:R-DME-3108214|reactome:R-DME-3899300|go:"GO:0030713"(ovarian follicle cell stalk formation)|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724|reactome:R-DME-8953750|refseq:NP_476871.2|flybase:FBgn0004861|dip:DIP-19426N pubmed:9499582(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6dlycV4Snf+YiEqKnJQEmicO9Zw7227 rogid:3pxds6HiNRg2p/Vcl7hFNcPInFI7227 intact-crc:25853651E851CBEF|rigid:QsqnMt7lXjq8U/lF8+ZA+FH4bV8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P35820 uniprotkb:P39769 intact:EBI-84600|uniprotkb:Q9V6I9|ensemblmetazoa:FBpp0086911|ensemblmetazoa:FBpp0311395|ensemblmetazoa:FBpp0311526 intact:EBI-300360|uniprotkb:O46097|uniprotkb:Q9W521|uniprotkb:Q9W522|ensemblmetazoa:FBpp0070416 psi-mi:psc_drome(display_long)|uniprotkb:Psc(gene name)|psi-mi:Psc(display_short)|uniprotkb:Protein posterior sex combs(gene name synonym)|uniprotkb:CG3886(orf name) psi-mi:php_drome(display_long)|uniprotkb:CG18412(orf name)|uniprotkb:ph-p(gene name)|psi-mi:ph-p(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873956 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523725.2|flybase:FBgn0005624|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0007419"(ventral cord development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-DME-3108214|reactome:R-DME-3899300|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724|reactome:R-DME-8953750|interpro:IPR001841(Zinc finger, RING-type)|ensemblmetazoa:FBgn0005624(gene)|ensemblmetazoa:FBtr0087798(transcript)|ensemblmetazoa:FBtr0345196(transcript)|ensemblmetazoa:FBtr0345375(transcript)|refseq:NP_001286368.1|refseq:NP_001286369.1 ensemblmetazoa:FBgn0004861(gene)|ensemblmetazoa:FBtr0070432(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051087"(chaperone binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P39769|rcsb pdb:1KW4|rcsb pdb:1PK1|reactome:R-DME-3108214|reactome:R-DME-3899300|go:"GO:0030713"(ovarian follicle cell stalk formation)|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724|reactome:R-DME-8953750|refseq:NP_476871.2|flybase:FBgn0004861|dip:DIP-19426N pubmed:9566890(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:C0LCX+uqZs0r5z4fFql91xQXLNs7227 rogid:3pxds6HiNRg2p/Vcl7hFNcPInFI7227 intact-crc:9C2469669899FE66|rigid:76Rm8KEZ6tNeoBfQB2cngYIdZp4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P21461 uniprotkb:Q27934 intact:EBI-77019|uniprotkb:A4V214|uniprotkb:Q9VVB0|ensemblmetazoa:FBpp0075091|ensemblmetazoa:FBpp0075092|ensemblmetazoa:FBpp0310636 intact:EBI-77033|uniprotkb:Q9V721|uniprotkb:C0PV22|ensemblmetazoa:FBpp0086645 psi-mi:sina_drome(display_long)|uniprotkb:sina(gene name)|psi-mi:sina(display_short)|uniprotkb:CG9949(orf name)|uniprotkb:Seven in absentia protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase sina(gene name synonym) psi-mi:phyl_drome(display_long)|uniprotkb:phyl(gene name)|psi-mi:phyl(display_short)|uniprotkb:CG10108(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873960 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476725.1|refseq:NP_730206.1|flybase:FBgn0003410|refseq:NP_001287089.1|dip:DIP-17392N|ensemblmetazoa:FBgn0003410(gene)|ensemblmetazoa:FBtr0075332(transcript)|ensemblmetazoa:FBtr0075333(transcript)|ensemblmetazoa:FBtr0344230(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007423"(sensory organ development)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|reactome:R-DME-373752|reactome:R-DME-5689880|reactome:R-DME-983168 refseq:NP_725394.1|flybase:FBgn0013725|dip:DIP-29101N|ensemblmetazoa:FBgn0013725(gene)|ensemblmetazoa:FBtr0087516(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007423"(sensory organ development)|go:"GO:0007462"(R1/R6 cell fate commitment)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008052"(sensory organ boundary specification)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D pubmed:9267027(see-also)|pubmed:8804311(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:GmUKLSW+fhn/1Fkti+v7o+NWs/87227 rogid:QocGYm5CUc0c4Z8raybzOGhpt1M7227 intact-crc:D8BE3498C8720565|rigid:P+ui+n2mQlnO4IJGO8pz4sikPeE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O18683 uniprotkb:P91634 intact:EBI-136889|uniprotkb:Q95SY4|uniprotkb:Q9VPN6|ensemblmetazoa:FBpp0303635 intact:EBI-173369|ensemblmetazoa:FBpp0083348|ensemblmetazoa:FBpp0083349|ensemblmetazoa:FBpp0306705 psi-mi:o18683_drome(display_long)|uniprotkb:Pi3K21B(gene name)|psi-mi:Pi3K21B(display_short)|uniprotkb:droPIK57(gene name synonym)|uniprotkb:p60(gene name synonym)|uniprotkb:CG2699(orf name) psi-mi:p91634_drome(display_long)|uniprotkb:Pi3K92E(gene name)|psi-mi:Pi3K92E(display_short)|uniprotkb:dp110(gene name synonym)|uniprotkb:DP110(gene name synonym)|uniprotkb:Dmel\CG4141(gene name synonym)|uniprotkb:Dmp110(gene name synonym)|uniprotkb:Dp110(gene name synonym)|uniprotkb:Dpp110(gene name synonym)|uniprotkb:"PI(3)K"(gene name synonym)|uniprotkb:PI-3 kinase(gene name synonym)|uniprotkb:PI-3-K(gene name synonym)|uniprotkb:PI3'K(gene name synonym)|uniprotkb:PI3K(gene name synonym)|uniprotkb:PI3K-92D(gene name synonym)|uniprotkb:PI3K-92E(gene name synonym)|uniprotkb:PI3K-Dp110(gene name synonym)|uniprotkb:PI3K-I(gene name synonym)|uniprotkb:PI3K-dp110(gene name synonym)|uniprotkb:PI3K92E(gene name synonym)|uniprotkb:PI3k(gene name synonym)|uniprotkb:PI[[3]]K(gene name synonym)|uniprotkb:Pi3K(gene name synonym)|uniprotkb:Pi3K92D(gene name synonym)|uniprotkb:"Pi3K92E|p110"(gene name synonym)|uniprotkb:Pi3Kp110(gene name synonym)|uniprotkb:Pi3k(gene name synonym)|uniprotkb:Pi3k92e(gene name synonym)|uniprotkb:PiK92E(gene name synonym)|uniprotkb:anon-92Ed(gene name synonym)|uniprotkb:dP110(gene name synonym)|uniprotkb:dP13K(gene name synonym)|uniprotkb:dPI3K(gene name synonym)|uniprotkb:dPI3K[92E](gene name synonym)|uniprotkb:dp110alpha(gene name synonym)|uniprotkb:p110(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pi3k(gene name synonym)|uniprotkb:pi3k92e(gene name synonym)|uniprotkb:rea(gene name synonym)|uniprotkb:type-1 PI3K(gene name synonym)|uniprotkb:Dmel_CG4141(orf name)|uniprotkb:CG4141(orf name)|uniprotkb:dpP110(gene name synonym)|uniprotkb:pi3k92E(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873964 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0020622|ensemblmetazoa:FBgn0020622(gene)|ensemblmetazoa:FBtr0331208(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016301"(kinase activity)|go:"GO:0019900"(kinase binding)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|interpro:IPR000980(SH2 motif)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR036860|reactome:R-DME-110478 refseq:NP_650902.1|refseq:NP_732536.1|flybase:FBgn0015279|refseq:NP_001262770.1|dip:DIP-21625N|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0045615"(positive regulation of plasmatocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035205"(positive regulation of lamellocyte differentiation)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|ensemblmetazoa:FBgn0015279(gene)|ensemblmetazoa:FBtr0083940(transcript)|ensemblmetazoa:FBtr0083941(transcript)|ensemblmetazoa:FBtr0334643(transcript)|go:"GO:0002164"(larval development)|go:"GO:0002168"(instar larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0006914"(autophagy)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007552"(metamorphosis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055115"(entry into diapause)|go:"GO:0060074"(synapse maturation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904801"(positive regulation of neuron remodeling)|go:"GO:2000252"(negative regulation of feeding behavior)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR042236|reactome:R-DME-109704|reactome:R-DME-110478|reactome:R-DME-112399|reactome:R-DME-114604|reactome:R-DME-1257604|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|reactome:R-DME-186763|reactome:R-DME-198203|reactome:R-DME-2730905|reactome:R-DME-4420097|reactome:R-DME-5673001|reactome:R-DME-6811558|reactome:R-DME-9027276|reactome:R-DME-912631|reactome:R-DME-983695|reactome:R-DME-1660499 pubmed:9169420(see-also)|pubmed:10508611(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:cdOgMluWy8oZsnsqWrhsxv1GfSg7227 rogid:6bV8IAtaMmbU7LHLOfyw1BGed/Q7227 intact-crc:0084254BC51A128A|rigid:5TtuVrgNFbgt8orocl6JeEIXm7Y false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42286 uniprotkb:Q24454 intact:EBI-673051|uniprotkb:Q8MQL8|uniprotkb:Q94525|uniprotkb:Q9V894 intact:EBI-145264|intact:EBI-1630237|ensemblmetazoa:FBpp0079591|ensemblmetazoa:FBpp0304499 psi-mi:thr_drome(display_long)|uniprotkb:thr(gene name)|psi-mi:thr(display_short)|uniprotkb:CG5785(orf name) psi-mi:q24454_drome(display_long)|uniprotkb:pim(gene name)|psi-mi:pim(display_short)|uniprotkb:pimples(gene name synonym)|uniprotkb:Dmel\CG5052(gene name synonym)|uniprotkb:PIM(gene name synonym)|uniprotkb:Pim(gene name synonym)|uniprotkb:frag2(gene name synonym)|uniprotkb:"l(2)31Df"(gene name synonym)|uniprotkb:sec(gene name synonym)|uniprotkb:CG5052(orf name)|uniprotkb:Dmel_CG5052(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873968 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_725731.2|flybase:FBgn0003701|refseq:NP_001286552.1|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005737"(cytoplasm)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007502"(digestive tract mesoderm development)|go:"GO:0008258"(head involution)|go:"GO:0008406"(gonad development)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation) refseq:NP_476678.1|flybase:FBgn0003087|refseq:NP_001260334.1|dip:DIP-22548N|ensemblmetazoa:FBgn0003087(gene)|ensemblmetazoa:FBtr0080001(transcript)|ensemblmetazoa:FBtr0332190(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007502"(digestive tract mesoderm development)|go:"GO:0008406"(gonad development)|go:"GO:0051306"(mitotic sister chromatid separation)|interpro:IPR006940(Securin sister-chromatid separation inhibitor) pubmed:10970883(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:a1Z9EE3khRRVl7Tre2muxb7S+NA7227 rogid:X6cKkEEKgZzltKwjAvhXjsgY4Ds7227 intact-crc:856E33822F11FABA|rigid:QAOg9ulWid1+YO8QoR7q+1zDDQY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VRN6 uniprotkb:Q24454 intact:EBI-103537|ensemblmetazoa:FBpp0076831 intact:EBI-145264|intact:EBI-1630237|ensemblmetazoa:FBpp0079591|ensemblmetazoa:FBpp0304499 psi-mi:q9vrn6_drome(display_long)|uniprotkb:Sse(gene name)|psi-mi:Sse(display_short)|uniprotkb:Dmel\CG10583(gene name synonym)|uniprotkb:SSE(gene name synonym)|uniprotkb:"l(3)13m-281"(gene name synonym)|uniprotkb:"l(3)SG14"(gene name synonym)|uniprotkb:sse(gene name synonym)|uniprotkb:Dmel_CG10583(orf name)|uniprotkb:CG10583(orf name) psi-mi:q24454_drome(display_long)|uniprotkb:pim(gene name)|psi-mi:pim(display_short)|uniprotkb:pimples(gene name synonym)|uniprotkb:Dmel\CG5052(gene name synonym)|uniprotkb:PIM(gene name synonym)|uniprotkb:Pim(gene name synonym)|uniprotkb:frag2(gene name synonym)|uniprotkb:"l(2)31Df"(gene name synonym)|uniprotkb:sec(gene name synonym)|uniprotkb:CG5052(orf name)|uniprotkb:Dmel_CG5052(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873972 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523935.1|flybase:FBgn0035627|ensemblmetazoa:FBgn0035627(gene)|ensemblmetazoa:FBtr0077125(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0016233"(telomere capping)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0140445"(chromosome, telomeric repeat region)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397 refseq:NP_476678.1|flybase:FBgn0003087|refseq:NP_001260334.1|dip:DIP-22548N|ensemblmetazoa:FBgn0003087(gene)|ensemblmetazoa:FBtr0080001(transcript)|ensemblmetazoa:FBtr0332190(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007502"(digestive tract mesoderm development)|go:"GO:0008406"(gonad development)|go:"GO:0051306"(mitotic sister chromatid separation)|interpro:IPR006940(Securin sister-chromatid separation inhibitor) pubmed:11581162(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Etx9K4pTD3ff7gIOzH8u16bE/5o7227 rogid:X6cKkEEKgZzltKwjAvhXjsgY4Ds7227 intact-crc:2A08A752C018551B|rigid:hSWh1cCLCF9iMoY8LeU/zRrZIz0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O44342 uniprotkb:Q86BJ3 intact:EBI-175131|uniprotkb:Q4V3T7|ensemblmetazoa:FBpp0085698|ensemblmetazoa:FBpp0309412 intact:EBI-167818|uniprotkb:O96662|uniprotkb:Q7KNQ1|uniprotkb:Q86BJ2|uniprotkb:Q86BJ4|uniprotkb:Q86BJ5|uniprotkb:Q86BJ6|uniprotkb:Q86BJ7|uniprotkb:Q86BJ8|uniprotkb:Q86BJ9|uniprotkb:Q86BK0|uniprotkb:Q8IQU0|uniprotkb:Q968U2|uniprotkb:Q9VVY5|uniprotkb:B9EQT7|uniprotkb:E1JI38|uniprotkb:E4NKL9|uniprotkb:E8NH03|uniprotkb:F2FB47|ensemblmetazoa:FBpp0074780 psi-mi:wbl_drome(display_long)|uniprotkb:wbl(gene name)|psi-mi:wbl(display_short)|uniprotkb:wind(gene name synonym)|uniprotkb:CG7225(orf name)|uniprotkb:Erp29 homolog(gene name synonym) psi-mi:pipe_drome(display_long)|uniprotkb:pip(gene name)|psi-mi:pip(display_short)|uniprotkb:CG9614(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873976 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_725867.1|flybase:FBgn0004003|refseq:NP_001286609.1|ensemblmetazoa:FBgn0004003(gene)|ensemblmetazoa:FBtr0086510(transcript)|ensemblmetazoa:FBtr0340470(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007313"(maternal specification of dorsal/ventral axis, oocyte, soma encoded)|go:"GO:0009306"(protein secretion)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR011679(Endoplasmic reticulum, protein ERp29, C-terminal)|interpro:IPR012883(ERp29, N-terminal)|interpro:IPR016855(Endoplasmic reticulum, protein ERp29)|interpro:IPR036249|interpro:IPR036356|rcsb pdb:1OVN|rcsb pdb:2C0E|rcsb pdb:2C0F|rcsb pdb:2C0G|rcsb pdb:2C1Y refseq:NP_001163467.1|refseq:NP_524158.2|refseq:NP_730402.1|refseq:NP_788529.1|refseq:NP_788530.1|refseq:NP_788531.1|refseq:NP_788532.1|refseq:NP_788533.1|refseq:NP_788534.1|refseq:NP_788536.1|refseq:NP_788537.1|flybase:FBgn0003089|refseq:NP_788535.2|ensemblmetazoa:FBtr0075013(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:1900005"(positive regulation of serine-type endopeptidase activity)|interpro:IPR005331(Carbohydrate sulphotransferase, 8-13)|interpro:IPR007734(Heparan sulphate 2-O-sulphotransferase)|interpro:IPR027417|reactome:R-DME-2022923|ensemblmetazoa:FBgn0003089(gene) pubmed:11076773(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Z25KXNTLbPaKsVED4oGolemTJG47227 rogid:GHsxgv7abXEUYH7N3GBweQWwH/E7227 intact-crc:B9B98E84BDAEDC39|rigid:82ijNlaFg0y7jcUZtu/PEoysnfg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q3YNB2 uniprotkb:O45030 intact:EBI-869336 intact:EBI-869122|ensemblmetazoa:FBpp0087647 psi-mi:q3ynb2_drome(display_long)|uniprotkb:pk(gene name)|psi-mi:pk(display_short)|uniprotkb:CG11084(orf name) psi-mi:o45030_drome(display_long)|uniprotkb:Vang(gene name)|psi-mi:Vang(display_short)|uniprotkb:stbm(gene name synonym)|uniprotkb:CG8075(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873980 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0003090 flybase:FBgn0015838|dip:DIP-35779N|ensemblmetazoa:FBgn0015838(gene)|ensemblmetazoa:FBtr0088566(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005109"(frizzled binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR009539(Strabismus)|reactome:R-DME-350368|reactome:R-DME-350376|reactome:R-DME-350379|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-450728 pubmed:12756182(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:VwW7JQR+5/MnS2Nvz7RID5sPxF47227 rogid:KK7iFNVimizORrJxiz5fcSV2f8c7227 intact-crc:D3EEC7AA4950B9B5|rigid:c3pj3fSDtvVXPbbkPcbu2LQTTBs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24496 uniprotkb:Q9W0V1 intact:EBI-870498 intact:EBI-220161|uniprotkb:O62534|uniprotkb:Q0E8K9|uniprotkb:Q53XF5|uniprotkb:Q7KVE1|uniprotkb:Q8IHG6|uniprotkb:Q9W0V2|uniprotkb:Q9W0V3|ensemblmetazoa:FBpp0072366|ensemblmetazoa:FBpp0305420 psi-mi:q24496_drome(display_long)|uniprotkb:S6kII(gene name)|psi-mi:S6kII(display_short)|uniprotkb:Rsk(gene name synonym)|uniprotkb:CG17596(orf name) psi-mi:pdpk1_drome(display_long)|uniprotkb:CG1210(orf name)|uniprotkb:Serine/threonine-protein kinase 61C(gene name synonym)|uniprotkb:dSTPK61(gene name synonym)|uniprotkb:Pdk1(gene name)|psi-mi:Pdk1(display_short)|uniprotkb:Pk61C(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873984 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0262866|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008306"(associative learning)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035106"(operant conditioning)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043204"(perikaryon)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0098793"(presynapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904396"(regulation of neuromuscular junction development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR041906|mint:Q24496 refseq:NP_525121.2|refseq:NP_728470.1|refseq:NP_728471.2|refseq:NP_728472.1|refseq:NP_728473.1|refseq:NP_728474.1|refseq:NP_728475.1|refseq:NP_728476.1|flybase:FBgn0020386|refseq:NP_001261183.1|dip:DIP-20399N|ensemblmetazoa:FBgn0020386(gene)|ensemblmetazoa:FBtr0072464(transcript)|ensemblmetazoa:FBtr0333218(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004676"(3-phosphoinositide-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033931|interpro:IPR039046|reactome:R-DME-110478|reactome:R-DME-110523|reactome:R-DME-114604|reactome:R-DME-1257604|reactome:R-DME-165158|reactome:R-DME-202424|reactome:R-DME-2730905|reactome:R-DME-389357|reactome:R-DME-392451|reactome:R-DME-5218920|reactome:R-DME-5218921|reactome:R-DME-5625740|reactome:R-DME-9634635 pubmed:11752451(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:vNwExu7op3Y6yfcdB+CRWw/rgbw7227 rogid:dkKE+FijB301ycXfm9AMunxRckI7227 intact-crc:13A13C9F53150EE8|rigid:cZlDSijyYw/zcwjoRaQGZM8LiKU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P91656 uniprotkb:Q9W0V1 intact:EBI-466629 intact:EBI-220161|uniprotkb:O62534|uniprotkb:Q0E8K9|uniprotkb:Q53XF5|uniprotkb:Q7KVE1|uniprotkb:Q8IHG6|uniprotkb:Q9W0V2|uniprotkb:Q9W0V3|ensemblmetazoa:FBpp0072366|ensemblmetazoa:FBpp0305420 psi-mi:p91656_drome(display_long)|uniprotkb:CG10539(orf name)|uniprotkb:S6k(gene name)|psi-mi:S6k(display_short) psi-mi:pdpk1_drome(display_long)|uniprotkb:CG1210(orf name)|uniprotkb:Serine/threonine-protein kinase 61C(gene name synonym)|uniprotkb:dSTPK61(gene name synonym)|uniprotkb:Pdk1(gene name)|psi-mi:Pdk1(display_short)|uniprotkb:Pk61C(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873988 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283472|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0031929"(TOR signaling)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:2000331"(regulation of terminal button organization)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016238(Ribosomal protein S6 kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|reactome:R-DME-110523|go:"GO:0008340"(determination of adult lifespan) refseq:NP_525121.2|refseq:NP_728470.1|refseq:NP_728471.2|refseq:NP_728472.1|refseq:NP_728473.1|refseq:NP_728474.1|refseq:NP_728475.1|refseq:NP_728476.1|flybase:FBgn0020386|refseq:NP_001261183.1|dip:DIP-20399N|ensemblmetazoa:FBgn0020386(gene)|ensemblmetazoa:FBtr0072464(transcript)|ensemblmetazoa:FBtr0333218(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004676"(3-phosphoinositide-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033931|interpro:IPR039046|reactome:R-DME-110478|reactome:R-DME-110523|reactome:R-DME-114604|reactome:R-DME-1257604|reactome:R-DME-165158|reactome:R-DME-202424|reactome:R-DME-2730905|reactome:R-DME-389357|reactome:R-DME-392451|reactome:R-DME-5218920|reactome:R-DME-5218921|reactome:R-DME-5625740|reactome:R-DME-9634635 pubmed:11752451(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:vY523/d3IX+Jh8UXjlIJaVVGFuw7227 rogid:dkKE+FijB301ycXfm9AMunxRckI7227 intact-crc:B300FC97C653A97D|rigid:51tUtLBwq+WJlMZtV5ay+WVxXck false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q03720 uniprotkb:P12370 intact:EBI-426805|uniprotkb:Q24369|uniprotkb:Q59DU0|uniprotkb:Q59DU1|uniprotkb:Q59DU2|uniprotkb:Q59DU3|uniprotkb:Q59DU4|uniprotkb:Q59DU5|uniprotkb:Q59DU6|uniprotkb:Q59DU7|uniprotkb:Q59DU8|uniprotkb:Q59DU9|uniprotkb:Q59DV0|uniprotkb:Q59DV1|uniprotkb:Q59DV2|uniprotkb:Q7KS13|uniprotkb:Q86NK5|uniprotkb:Q8IMV9|uniprotkb:Q9TWA1|uniprotkb:Q9VC51|uniprotkb:A4V3D4|uniprotkb:Q24384|uniprotkb:Q24385|uniprotkb:Q7JP74|ensemblmetazoa:FBpp0100095 intact:EBI-82224|uniprotkb:Q9VL99|uniprotkb:A4V0I0|ensemblmetazoa:FBpp0079448|ensemblmetazoa:FBpp0089382|ensemblmetazoa:FBpp0307466 psi-mi:slo_drome(display_long)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:slo(gene name)|psi-mi:slo(display_short)|uniprotkb:CG10693(orf name) psi-mi:kapc1_drome(display_long)|uniprotkb:Pka-C1(gene name)|psi-mi:Pka-C1(display_short)|uniprotkb:CdkA(gene name synonym)|uniprotkb:DC0(gene name synonym)|uniprotkb:Protein kinase DC0(gene name synonym)|uniprotkb:CG4379(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873992 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014660.1|refseq:NP_001014661.2|refseq:NP_001014662.1|refseq:NP_001014663.1|refseq:NP_001014664.1|refseq:NP_524486.2|refseq:NP_733029.1|refseq:NP_996289.1|flybase:FBgn0003429|refseq:NP_001014651.1|refseq:NP_001014652.1|refseq:NP_001014653.1|refseq:NP_001014654.1|refseq:NP_001014655.1|refseq:NP_001014656.1|refseq:NP_001014657.1|refseq:NP_001014658.1|refseq:NP_001014659.1|ensemblmetazoa:FBgn0003429(gene)|ensemblmetazoa:FBtr0100635(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0048512"(circadian behavior)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-DME-1300642 ensemblmetazoa:FBgn0000273(gene)|ensemblmetazoa:FBtr0079851(transcript)|ensemblmetazoa:FBtr0079852(transcript)|ensemblmetazoa:FBtr0335495(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007615"(anesthesia-resistant memory)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008355"(olfactory learning)|go:"GO:0008359"(regulation of bicoid mRNA localization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046823"(negative regulation of nucleocytoplasmic transport)|go:"GO:0048477"(oogenesis)|go:"GO:0048682"(sprouting of injured axon)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P12370|reactome:R-DME-163615|reactome:R-DME-164378|reactome:R-DME-180024|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209360|reactome:R-DME-381676|reactome:R-DME-392517|reactome:R-DME-432040|reactome:R-DME-4420097|reactome:R-DME-442720|reactome:R-DME-5578775|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5621575|reactome:R-DME-983231|refseq:NP_723479.1|refseq:NP_995672.1|flybase:FBgn0000273|refseq:NP_476977.1|dip:DIP-23727N pubmed:12019304(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:RJ1d6NqNTG7hU0pHboPIRa1PesE7227 rogid:e7pEt3E/V/RB/nj6uqwtAs5u1js7227 intact-crc:4F27413435AE4483|rigid:qx8e/iUMNErzwYi5hym9e7KTrWI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P12370 uniprotkb:P18459 intact:EBI-82224|uniprotkb:Q9VL99|uniprotkb:A4V0I0|ensemblmetazoa:FBpp0079448|ensemblmetazoa:FBpp0089382|ensemblmetazoa:FBpp0307466 intact:EBI-198234|uniprotkb:Q24000|uniprotkb:Q8SY95|ensemblmetazoa:FBpp0076666|ensemblmetazoa:FBpp0311654 psi-mi:kapc1_drome(display_long)|uniprotkb:Pka-C1(gene name)|psi-mi:Pka-C1(display_short)|uniprotkb:CdkA(gene name synonym)|uniprotkb:DC0(gene name synonym)|uniprotkb:Protein kinase DC0(gene name synonym)|uniprotkb:CG4379(orf name) psi-mi:ty3h_drome(display_long)|uniprotkb:ple(gene name)|psi-mi:ple(display_short)|uniprotkb:TH(gene name synonym)|uniprotkb:CG10118(orf name)|uniprotkb:Tyrosine 3-hydroxylase(gene name synonym)|uniprotkb:Protein Pale(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-873996 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0000273(gene)|ensemblmetazoa:FBtr0079851(transcript)|ensemblmetazoa:FBtr0079852(transcript)|ensemblmetazoa:FBtr0335495(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007615"(anesthesia-resistant memory)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008355"(olfactory learning)|go:"GO:0008359"(regulation of bicoid mRNA localization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046823"(negative regulation of nucleocytoplasmic transport)|go:"GO:0048477"(oogenesis)|go:"GO:0048682"(sprouting of injured axon)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P12370|reactome:R-DME-163615|reactome:R-DME-164378|reactome:R-DME-180024|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209360|reactome:R-DME-381676|reactome:R-DME-392517|reactome:R-DME-432040|reactome:R-DME-4420097|reactome:R-DME-442720|reactome:R-DME-5578775|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5621575|reactome:R-DME-983231|refseq:NP_723479.1|refseq:NP_995672.1|flybase:FBgn0000273|refseq:NP_476977.1|dip:DIP-23727N refseq:NP_001286955.1|refseq:NP_476897.1|refseq:NP_476898.1|flybase:FBgn0005626|dip:DIP-17399N|ensemblmetazoa:FBgn0005626(gene)|ensemblmetazoa:FBtr0076957(transcript)|ensemblmetazoa:FBtr0345585(transcript)|go:"GO:0004511"(tyrosine 3-monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006584"(catecholamine metabolic process)|go:"GO:0006585"(dopamine biosynthetic process from tyrosine)|go:"GO:0007619"(courtship behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009611"(response to wounding)|go:"GO:0030424"(axon)|go:"GO:0035220"(wing disc development)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043052"(thermotaxis)|go:"GO:0043204"(perikaryon)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048067"(cuticle pigmentation)|go:"GO:0048082"(regulation of adult chitin-containing cuticle pigmentation)|go:"GO:0048085"(adult chitin-containing cuticle pigmentation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|interpro:IPR001273(Aromatic amino acid hydroxylase)|interpro:IPR005962(Tyrosine 3-monooxygenase)|interpro:IPR018301|interpro:IPR019773|interpro:IPR019774|interpro:IPR036329|interpro:IPR036951|interpro:IPR041903|reactome:R-DME-209905 pubmed:10358021(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:e7pEt3E/V/RB/nj6uqwtAs5u1js7227 rogid:v3PWaGA7WyGUNBVTl4B+Ndsj3TM7227 intact-crc:89B7BBBA5F44EE95|rigid:sFVNQLcSiOJhcxBgci1vg75JicM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P81900 uniprotkb:P12370 intact:EBI-129349|uniprotkb:A1A6P8|uniprotkb:A1A6T9|uniprotkb:A2RVH2|uniprotkb:A4UZA6|uniprotkb:Q9NB18|uniprotkb:Q9V5E8|uniprotkb:A8DY87|uniprotkb:A8DY88|ensemblmetazoa:FBpp0087523|ensemblmetazoa:FBpp0087524 intact:EBI-82224|uniprotkb:Q9VL99|uniprotkb:A4V0I0|ensemblmetazoa:FBpp0079448|ensemblmetazoa:FBpp0089382|ensemblmetazoa:FBpp0307466 psi-mi:kapr2_drome(display_long)|uniprotkb:Pka-R2(gene name)|psi-mi:Pka-R2(display_short)|uniprotkb:pka-RII(gene name synonym)|uniprotkb:CG15862(orf name) psi-mi:kapc1_drome(display_long)|uniprotkb:Pka-C1(gene name)|psi-mi:Pka-C1(display_short)|uniprotkb:CdkA(gene name synonym)|uniprotkb:DC0(gene name synonym)|uniprotkb:Protein kinase DC0(gene name synonym)|uniprotkb:CG4379(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874000 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097251.1|refseq:NP_001097252.1|refseq:NP_523671.1|refseq:NP_724860.2|flybase:FBgn0022382|ensemblmetazoa:FBgn0022382(gene)|ensemblmetazoa:FBtr0088437(transcript)|ensemblmetazoa:FBtr0088438(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0007411"(axon guidance)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0071361"(cellular response to ethanol)|reactome:R-DME-432040|reactome:R-DME-442720|reactome:R-DME-5610787|reactome:R-DME-983231|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|reactome:R-DME-163615|reactome:R-DME-164378|reactome:R-DME-180024 ensemblmetazoa:FBgn0000273(gene)|ensemblmetazoa:FBtr0079851(transcript)|ensemblmetazoa:FBtr0079852(transcript)|ensemblmetazoa:FBtr0335495(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007615"(anesthesia-resistant memory)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008355"(olfactory learning)|go:"GO:0008359"(regulation of bicoid mRNA localization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046823"(negative regulation of nucleocytoplasmic transport)|go:"GO:0048477"(oogenesis)|go:"GO:0048682"(sprouting of injured axon)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P12370|reactome:R-DME-163615|reactome:R-DME-164378|reactome:R-DME-180024|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209360|reactome:R-DME-381676|reactome:R-DME-392517|reactome:R-DME-432040|reactome:R-DME-4420097|reactome:R-DME-442720|reactome:R-DME-5578775|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5621575|reactome:R-DME-983231|refseq:NP_723479.1|refseq:NP_995672.1|flybase:FBgn0000273|refseq:NP_476977.1|dip:DIP-23727N pubmed:9212068(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:9M/7Vjr9IVwctYgRi64MH+Ys5fs7227 rogid:e7pEt3E/V/RB/nj6uqwtAs5u1js7227 intact-crc:1E6643FC6254369F|rigid:DzxDsBvbo9X5zf36Y5rman1zA0U false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q99323 uniprotkb:P05130 intact:EBI-118064|uniprotkb:Q24138|uniprotkb:Q7JPC1|uniprotkb:Q7JPC2|uniprotkb:Q8MMC2|uniprotkb:Q94987|uniprotkb:Q94992|uniprotkb:Q9W0W8 intact:EBI-870512|uniprotkb:Q9V7V6|uniprotkb:Q9V7V7|ensemblmetazoa:FBpp0086197 psi-mi:mysn_drome(display_long)|uniprotkb:zip(gene name)|psi-mi:zip(display_short)|uniprotkb:CG15792(orf name)|uniprotkb:Zipper protein(gene name synonym)|uniprotkb:Myosin II(gene name synonym)|uniprotkb:Non-muscle MHC(gene name synonym) psi-mi:kpc1_drome(display_long)|uniprotkb:"dPKC53E(BR)"(gene name synonym)|uniprotkb:Pkc53E(gene name)|psi-mi:Pkc53E(display_short)|uniprotkb:PKC1(gene name synonym)|uniprotkb:CG6622(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874004 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005938"(cell cortex)|go:"GO:0006936"(muscle contraction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007496"(anterior midgut development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008258"(head involution)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0030239"(myofibril assembly)|go:"GO:0031036"(myosin II filament assembly)|go:"GO:0031252"(cell leading edge)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0005524"(ATP binding)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046663"(dorsal closure, leading edge cell differentiation)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0051015"(actin filament binding)|go:"GO:0060289"(compartment boundary maintenance)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|refseq:NP_523860.2|refseq:NP_726506.1|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|reactome:R-DME-350480|reactome:R-DME-5627123|flybase:FBgn0287873 refseq:NP_476682.1|refseq:NP_725626.1|flybase:FBgn0003091|refseq:NP_001261035.1|ensemblmetazoa:FBgn0003091(gene)|ensemblmetazoa:FBtr0087048(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR035892|reactome:R-DME-111933|reactome:R-DME-114516|reactome:R-DME-1169091|reactome:R-DME-1250196|reactome:R-DME-1433559|reactome:R-DME-2179392|reactome:R-DME-3000170|reactome:R-DME-399997|reactome:R-DME-4419969|reactome:R-DME-450520|reactome:R-DME-5099900|reactome:R-DME-5218921|reactome:R-DME-76005 pubmed:11297427(see-also) crc64:0D59519C1E83A411 - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:G6d6geCoR3HKWHNwB69h8p2n8cA7227 rogid:xg6G6xHaNSKnYMwjJXUAaxYK7tg7227 intact-crc:5CF0D800092BCDE9|rigid:ILWsbvG8X2PpG4skvUTPzezc8cc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P15348 uniprotkb:P05130 intact:EBI-134105|uniprotkb:Q9VIW2|uniprotkb:Q6NR40|uniprotkb:M9PDQ1|ensemblmetazoa:FBpp0080825|ensemblmetazoa:FBpp0304598 intact:EBI-870512|uniprotkb:Q9V7V6|uniprotkb:Q9V7V7|ensemblmetazoa:FBpp0086197 psi-mi:top2_drome(display_long)|uniprotkb:Top2(gene name)|psi-mi:Top2(display_short)|uniprotkb:CG10223(orf name)|uniprotkb:DNA topoisomerase II(gene name synonym) psi-mi:kpc1_drome(display_long)|uniprotkb:"dPKC53E(BR)"(gene name synonym)|uniprotkb:Pkc53E(gene name)|psi-mi:Pkc53E(display_short)|uniprotkb:PKC1(gene name synonym)|uniprotkb:CG6622(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874008 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0284220|refseq:NP_476760.1|refseq:NP_001260580.1|ensemblmetazoa:FBgn0284220(gene)|ensemblmetazoa:FBtr0081287(transcript)|ensemblmetazoa:FBtr0332320(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006342"|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008623"(CHRAC)|go:"GO:0030261"(chromosome condensation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|interpro:IPR020568|interpro:IPR031660|interpro:IPR034157|interpro:IPR036890|reactome:R-DME-4615885 refseq:NP_476682.1|refseq:NP_725626.1|flybase:FBgn0003091|refseq:NP_001261035.1|ensemblmetazoa:FBgn0003091(gene)|ensemblmetazoa:FBtr0087048(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR035892|reactome:R-DME-111933|reactome:R-DME-114516|reactome:R-DME-1169091|reactome:R-DME-1250196|reactome:R-DME-1433559|reactome:R-DME-2179392|reactome:R-DME-3000170|reactome:R-DME-399997|reactome:R-DME-4419969|reactome:R-DME-450520|reactome:R-DME-5099900|reactome:R-DME-5218921|reactome:R-DME-76005 pubmed:8383533(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:EkijDVP5cT0HlKzmQhXsNTYxwms7227 rogid:xg6G6xHaNSKnYMwjJXUAaxYK7tg7227 intact-crc:4F74739E46A0BB3B|rigid:lFsc7DCrPiBKEpqis+GO5AYxVRI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P48596 uniprotkb:P18459 intact:EBI-285547|uniprotkb:Q6TY66|uniprotkb:Q6TY71|uniprotkb:Q6TY73|uniprotkb:Q6TY74|uniprotkb:Q6TY78|uniprotkb:Q960S4|uniprotkb:Q9W2J9|uniprotkb:Q9W2K1|uniprotkb:Q9Y0C8|ensemblmetazoa:FBpp0071507 intact:EBI-198234|uniprotkb:Q24000|uniprotkb:Q8SY95|ensemblmetazoa:FBpp0076666|ensemblmetazoa:FBpp0311654 psi-mi:gch1_drome(display_long)|uniprotkb:GTP cyclohydrolase I(gene name synonym)|uniprotkb:Protein punch(gene name synonym)|uniprotkb:Pu(gene name)|psi-mi:Pu(display_short)|uniprotkb:CG9441(orf name) psi-mi:ty3h_drome(display_long)|uniprotkb:ple(gene name)|psi-mi:ple(display_short)|uniprotkb:TH(gene name synonym)|uniprotkb:CG10118(orf name)|uniprotkb:Tyrosine 3-hydroxylase(gene name synonym)|uniprotkb:Protein Pale(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874012 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523801.2|refseq:NP_726037.1|refseq:NP_726038.1|flybase:FBgn0003162|dip:DIP-24104N|ensemblmetazoa:FBgn0003162(gene)|ensemblmetazoa:FBtr0071580(transcript)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006728"(pteridine biosynthetic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008363"(larval chitin-based cuticle development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0035185"(preblastoderm mitotic cell cycle)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0043095"(regulation of GTP cyclohydrolase I activity)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0048067"(cuticle pigmentation)|go:"GO:0048072"(compound eye pigmentation)|go:"GO:0060308"(GTP cyclohydrolase I regulator activity)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|reactome:R-DME-1474151 refseq:NP_001286955.1|refseq:NP_476897.1|refseq:NP_476898.1|flybase:FBgn0005626|dip:DIP-17399N|ensemblmetazoa:FBgn0005626(gene)|ensemblmetazoa:FBtr0076957(transcript)|ensemblmetazoa:FBtr0345585(transcript)|go:"GO:0004511"(tyrosine 3-monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006584"(catecholamine metabolic process)|go:"GO:0006585"(dopamine biosynthetic process from tyrosine)|go:"GO:0007619"(courtship behavior)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009611"(response to wounding)|go:"GO:0030424"(axon)|go:"GO:0035220"(wing disc development)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043052"(thermotaxis)|go:"GO:0043204"(perikaryon)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048067"(cuticle pigmentation)|go:"GO:0048082"(regulation of adult chitin-containing cuticle pigmentation)|go:"GO:0048085"(adult chitin-containing cuticle pigmentation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|interpro:IPR001273(Aromatic amino acid hydroxylase)|interpro:IPR005962(Tyrosine 3-monooxygenase)|interpro:IPR018301|interpro:IPR019773|interpro:IPR019774|interpro:IPR036329|interpro:IPR036951|interpro:IPR041903|reactome:R-DME-209905 pubmed:10938545(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:3jUT2gsUKC+uh2YGFQB+G/Ri7nY7227 rogid:v3PWaGA7WyGUNBVTl4B+Ndsj3TM7227 intact-crc:4A29CFE2633C1634|rigid:dhT74eUu7gW4HvziQjszksz/4qE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O44253 uniprotkb:O96681 intact:EBI-870538 intact:EBI-870234 psi-mi:o44253_drome(display_long)|uniprotkb:Sema1b(gene name)|psi-mi:Sema1b(display_short)|uniprotkb:Sema-1b(gene name synonym)|uniprotkb:CG6446(orf name) psi-mi:o96681_drome(display_long)|uniprotkb:PlexA(gene name)|psi-mi:PlexA(display_short)|uniprotkb:plexA(gene name synonym)|uniprotkb:CG11081(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874016 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0016059|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007411"(axon guidance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR027231|interpro:IPR036352|interpro:IPR042068 flybase:FBgn0025741|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0030250"(guanylate cyclase activator activity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097374"(sensory neuron axon guidance)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:2000305"(semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362 pubmed:9875845(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6cp+/5w99sqIf2/DlTABwdoupiE7227 rogid:+9+nmrm+OrwkG/mEh1tqH0IC5C47227 intact-crc:673851CA143EE6E9|rigid:fpAzZ28lbAvLpOxWTW0+rRymC2w false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24322 uniprotkb:O96681 intact:EBI-497707|ensemblmetazoa:FBpp0079302|intact:EBI-522430|intact:EBI-2508878|uniprotkb:Q8MYZ9 intact:EBI-870234 psi-mi:sem1a_drome(display_long)|uniprotkb:Sema1a(gene name)|psi-mi:Sema1a(display_short)|uniprotkb:Sema-1a(gene name synonym)|uniprotkb:Dsema-I(gene name synonym)|uniprotkb:Semaphorin-I(gene name synonym)|uniprotkb:CG18405(orf name) psi-mi:o96681_drome(display_long)|uniprotkb:PlexA(gene name)|psi-mi:PlexA(display_short)|uniprotkb:plexA(gene name synonym)|uniprotkb:CG11081(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874020 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0008039"(synaptic target recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:2000305"(semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|go:"GO:0007416"(synapse assembly)|ensemblmetazoa:FBgn0011259(gene)|ensemblmetazoa:FBtr0079691(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|flybase:FBgn0011259|refseq:NP_723407.2|interpro:IPR002165(Plexin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036352|interpro:IPR042068|rcsb pdb:6QP9|reactome:R-DME-399954|reactome:R-DME-399955|reactome:R-DME-399956|reactome:R-DME-416572|reactome:R-DME-416700 flybase:FBgn0025741|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0030250"(guanylate cyclase activator activity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097374"(sensory neuron axon guidance)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:2000305"(semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362 pubmed:9875845(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2018/03/08 rogid:/HX4NjzE/t8Y1ez/ymSSxSymbpM7227 rogid:+9+nmrm+OrwkG/mEh1tqH0IC5C47227 intact-crc:A297F8BBA8316737|rigid:3gK/JEAI/J/S10lmzOzPooYroNs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40792 uniprotkb:Q9V4A7 intact:EBI-74845|uniprotkb:Q9W0H7|ensemblmetazoa:FBpp0072614|ensemblmetazoa:FBpp0304252 intact:EBI-125503|uniprotkb:O96682|ensemblmetazoa:FBpp0088246|ensemblmetazoa:FBpp0300616 psi-mi:rac1_drome(display_long)|uniprotkb:Rac1(gene name)|psi-mi:Rac1(display_short)|uniprotkb:RacA(gene name synonym)|uniprotkb:CG2248(orf name) psi-mi:plxb_drome(display_long)|uniprotkb:PlexB(gene name)|psi-mi:PlexB(display_short)|uniprotkb:CG17245(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874024 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476950.1|flybase:FBgn0010333|refseq:NP_001261247.1|ensemblmetazoa:FBgn0010333(gene)|ensemblmetazoa:FBtr0072730(transcript)|ensemblmetazoa:FBtr0331868(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002433"(immune response-regulating cell surface receptor signaling pathway involved in phagocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007394"(dorsal closure, elongation of leading edge cells)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007516"(hemocyte development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007613"(memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008258"(head involution)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0016028"(rhabdomere)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016203"(muscle attachment)|go:"GO:0016358"(dendrite development)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035010"(encapsulation of foreign target)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0035320"(imaginal disc-derived wing hair site selection)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048675"(axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0055001"(muscle cell development)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097206"(nephrocyte filtration)|go:"GO:0110125"(negative regulation of myotube cell migration)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1903391"(regulation of adherens junction organization)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-1433557|reactome:R-DME-193648|reactome:R-DME-2029482|reactome:R-DME-2871796|reactome:R-DME-350376|reactome:R-DME-376172|reactome:R-DME-389359|reactome:R-DME-3928662|reactome:R-DME-3928664|reactome:R-DME-3928665|reactome:R-DME-399954|reactome:R-DME-4086400|reactome:R-DME-4420097|reactome:R-DME-445144|reactome:R-DME-5218920|reactome:R-DME-5625740|reactome:R-DME-5627123|reactome:R-DME-5663213|reactome:R-DME-5687128|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-9013407|reactome:R-DME-9706019|reactome:R-DME-983231 refseq:NP_524616.2|flybase:FBgn0025740|ensemblmetazoa:FBgn0025740(gene)|ensemblmetazoa:FBtr0089179(transcript)|ensemblmetazoa:FBtr0308297(transcript)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0071678"(olfactory bulb axon guidance)|go:"GO:0097374"(sensory neuron axon guidance)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0008045"(motor neuron axon guidance)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|reactome:R-DME-399954|interpro:IPR016201(Plexin-like fold)|reactome:R-DME-399955|reactome:R-DME-399956|reactome:R-DME-416482|reactome:R-DME-416572|reactome:R-DME-416700|refseq:NP_001245400.1 pubmed:11267870(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:nVrsdRuWmYjJp67rd4Es0mFDuUU7227 rogid:350iheu3SPjBIQExJbdqF9HKew47227 intact-crc:B03B7CA0FBE10448|rigid:X8JMe2Owx6U3uhFDkr079Oy+jd8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q05652 uniprotkb:O77237 intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005 intact:EBI-92779|ensemblmetazoa:FBpp0083913|ensemblmetazoa:FBpp0111820 psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short) psi-mi:peli_drome(display_long)|uniprotkb:Pli(gene name)|psi-mi:Pli(display_short)|uniprotkb:CG5212(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874028 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N refseq:NP_001097890.1|refseq:NP_524466.1|flybase:FBgn0025574|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|interpro:IPR006800(Pellino)|reactome:R-DME-9020702|go:"GO:0061630"(ubiquitin protein ligase activity)|ensemblmetazoa:FBgn0025574(gene)|ensemblmetazoa:FBtr0084527(transcript)|ensemblmetazoa:FBtr0112907(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045751"(negative regulation of Toll signaling pathway)|go:"GO:0045752"(positive regulation of Toll signaling pathway) pubmed:10330490(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227 rogid:f6A3mbxIheYPOEzfh7GdL3o+m487227 intact-crc:4B77624003FC974F|rigid:8aWB6GaKYAlpUaNHrwn04U7t45s false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P22812 uniprotkb:Q05652 intact:EBI-93181|uniprotkb:Q9VN15|uniprotkb:B7Z0I9|uniprotkb:E8NH30|ensemblmetazoa:FBpp0291542 intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005 psi-mi:tube_drome(display_long)|uniprotkb:CG10520(orf name)|uniprotkb:tub(gene name)|psi-mi:tub(display_short)|uniprotkb:tube(gene name synonym) psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874032 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189164.1|flybase:FBgn0003882|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR029397|rcsb pdb:1D2Z|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874|go:"GO:0045087"(innate immune response)|ensemblmetazoa:FBgn0003882(gene)|ensemblmetazoa:FBtr0302338(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009620"(response to fungus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|dip:DIP-27623N refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N pubmed:7635064(see-also)|pubmed:7527496(see-also)|pubmed:10330490(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:v00LZV72cvvYVI5cCthONXIlmrs7227 rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227 intact-crc:FCC46BA434CFABCF|rigid:CBP6+LAxAvEVwY1/uwqyn2iFqUM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9UAC4 uniprotkb:Q05652 intact:EBI-527076 intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005 psi-mi:q9uac4_drome(display_long)|uniprotkb:CG10961(orf name)|uniprotkb:Traf6(gene name)|psi-mi:Traf6(display_short)|uniprotkb:Traf2(gene name synonym) psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874036 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0265464|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007391"(dorsal closure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|interpro:IPR037309|interpro:IPR043211|interpro:IPR001841(Zinc finger, RING-type) refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N pubmed:11447260(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:C8hRDKjO0PpD0SFyvjEbYh3dCyo7227 rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227 intact-crc:FF6E720E14208D3A|rigid:A4/bTGG/kg26UnsTAJDOeaYnIXk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9UAC5 uniprotkb:Q05652 intact:EBI-868447 intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005 psi-mi:q9uac5_drome(display_long)|uniprotkb:Traf4(gene name)|psi-mi:Traf4(display_short)|uniprotkb:traf1(gene name synonym)|uniprotkb:CG3048(orf name)|uniprotkb:Traf1(gene name synonym) psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874040 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0026319|go:"GO:0001654"(eye development)|go:"GO:0003384"(apical constriction involved in gastrulation)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045177"(apical part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|go:"GO:0034332"(adherens junction organization) refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N pubmed:10766844(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:I+bBjRvDZ/MnoA5YyVxty92NBzE7227 rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227 intact-crc:EB7F720E0F514D51|rigid:dnGJW+C2iIydmcMADsBy2Qypcho false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08953 uniprotkb:Q05652 intact:EBI-143610|uniprotkb:A4V3G7|uniprotkb:A8WHK7|uniprotkb:Q8MRF3|uniprotkb:Q9VBB8|ensemblmetazoa:FBpp0084431|ensemblmetazoa:FBpp0303188 intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005 psi-mi:toll_drome(display_long)|uniprotkb:Tl(gene name)|psi-mi:Tl(display_short)|uniprotkb:CG5490(orf name) psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874044 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524518.1|refseq:NP_733166.1|flybase:FBgn0262473|dip:DIP-34358N|ensemblmetazoa:FBgn0262473(gene)|ensemblmetazoa:FBtr0085059(transcript)|ensemblmetazoa:FBtr0330155(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002229"(defense response to oomycetes)|go:"GO:0002347"(response to tumor cell)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007507"(heart development)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009597"(detection of virus)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0019955"(cytokine binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046790"(virion binding)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0070976"(TIR domain binding)|go:"GO:1902875"(regulation of embryonic pattern specification)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR026906|interpro:IPR032675|interpro:IPR035897|rcsb pdb:4ARN|rcsb pdb:4ARR|rcsb pdb:4BV4|rcsb pdb:4LXR|rcsb pdb:4LXS|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874 refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N pubmed:9806920(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6nIbDMNS71rQ+CzvUkspyPjTd707227 rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227 intact-crc:DB22F6E761ABD8AA|rigid:pxRs1AwlQZCB9CtIyq74wueiWz0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q58S70 uniprotkb:Q05652 intact:EBI-870559 intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005 psi-mi:q58s70_drome(display_long)|uniprotkb:Tehao(gene name)|psi-mi:Tehao(display_short)|uniprotkb:CG7121(orf name) psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874048 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0026760|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002807"(positive regulation of antimicrobial peptide biosynthetic process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005121"(Toll binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0015026"(coreceptor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045087"(innate immune response)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR017241(Toll-like receptor)|interpro:IPR032675|interpro:IPR035897 refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N pubmed:11881810(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:tUWoWWASlihkjMy1WccWibQZfZQ7227 rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227 intact-crc:436367B3D32CA005|rigid:nrA1MoAOIyFhKE/d05QuaCZ8X1g false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q05652 uniprotkb:Q05652 intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005 intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005 psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short) psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874052 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N pubmed:9806920(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227 rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227 intact-crc:05FFAAD26CAA6938|rigid:f+i9vle8f38FRFrpN6AYDoG/4f0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O46308 uniprotkb:P42570 intact:EBI-137864|ensemblmetazoa:FBpp0070225 intact:EBI-191930|uniprotkb:Q9V910|ensemblmetazoa:FBpp0085618 psi-mi:o46308_drome(display_long)|uniprotkb:png(gene name)|psi-mi:png(display_short)|uniprotkb:"EG:8D8.5"(gene name synonym)|uniprotkb:Dmel\CG11420(gene name synonym)|uniprotkb:PNG(gene name synonym)|uniprotkb:Png(gene name synonym)|uniprotkb:"fs(1)M2"(gene name synonym)|uniprotkb:pan-gnu(gene name synonym)|uniprotkb:Dmel_CG11420(orf name)|uniprotkb:"fs(1)N"(gene name synonym)|uniprotkb:CG11420(orf name) psi-mi:plu_drome(display_long)|uniprotkb:plu(gene name)|psi-mi:plu(display_short)|uniprotkb:CG9183(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874056 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477492.1|flybase:FBgn0000826|dip:DIP-19818N|ensemblmetazoa:FBgn0000826(gene)|ensemblmetazoa:FBtr0070234(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007343"(egg activation)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1902911"(protein kinase complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like) dip:DIP-24015N|refseq:NP_476683.1|flybase:FBgn0003114|ensemblmetazoa:FBgn0003114(gene)|ensemblmetazoa:FBtr0086306(transcript)|go:"GO:0006260"(DNA replication)|go:"GO:0007338"(single fertilization)|go:"GO:0007343"(egg activation)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:1902554"(serine/threonine protein kinase complex)|go:"GO:1902911"(protein kinase complex)|interpro:IPR002110(Ankyrin)|interpro:IPR036770 pubmed:14665672(see-also)|pubmed:11044392(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:edS/8LZU3aJj4+A1YmKxmD5wQY87227 rogid:esFQ1m3oOpifUY5WIqUy4bdA8+U7227 intact-crc:D827DBCEFB7CA131|rigid:gQAd79K5shl8H3Jj82tN+VoNbwY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VPQ6 uniprotkb:P52168 intact:EBI-110692|uniprotkb:Q6AWH0|uniprotkb:O18414|ensemblmetazoa:FBpp0077723 intact:EBI-144873|ensemblmetazoa:FBpp0082675 psi-mi:ush_drome(display_long)|uniprotkb:Protein U-shaped(gene name synonym)|uniprotkb:ush(gene name)|psi-mi:ush(display_short)|uniprotkb:CG2762(orf name) psi-mi:pnr_drome(display_long)|uniprotkb:pnr(gene name)|psi-mi:pnr(display_short)|uniprotkb:GATA-A(gene name synonym)|uniprotkb:CG3978(orf name)|uniprotkb:Transcription factor GATA-A(gene name synonym)|uniprotkb:dGATA-A(gene name synonym)|uniprotkb:Protein pannier(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874060 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476780.1|flybase:FBgn0003963|ensemblmetazoa:FBgn0003963(gene)|ensemblmetazoa:FBtr0078063(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007507"(heart development)|go:"GO:0022416"(chaeta development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046665"(amnioserosa maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048542"(lymph gland development)|go:"GO:0048749"(compound eye development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034731|interpro:IPR036236|interpro:IPR039746|rcsb pdb:1FU9|rcsb pdb:1FV5|rcsb pdb:1JN7|rcsb pdb:1Y0J|rcsb pdb:2L6Z|reactome:R-DME-8936459|reactome:R-DME-983231 refseq:NP_476685.1|flybase:FBgn0003117|ensemblmetazoa:FBgn0003117(gene)|ensemblmetazoa:FBtr0083221(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007510"(cardioblast cell fate determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0022416"(chaeta development)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035051"(cardiocyte differentiation)|go:"GO:0042440"(pigment metabolic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048542"(lymph gland development)|go:"GO:0060047"(heart contraction)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|reactome:R-DME-5683826|reactome:R-DME-983231 pubmed:9367990(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:2CAaxvMNBtN3JUFnhUgsOAMFmYM7227 rogid:G0/pi+DhH2ncsNG77KXtUPOrH7M7227 intact-crc:521B76307FF2AF29|rigid:inr8wUYafSZUJX71DPaKYssi4sE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P22711 uniprotkb:P52168 intact:EBI-143325|intact:EBI-1629549|uniprotkb:Q6AWK6|uniprotkb:Q6UKJ7|uniprotkb:Q6UKK8|uniprotkb:Q6UKL1|uniprotkb:Q6UKL4|uniprotkb:Q6UKL5|uniprotkb:Q9TY85|uniprotkb:Q9VDA7|ensemblmetazoa:FBpp0083485 intact:EBI-144873|ensemblmetazoa:FBpp0082675 psi-mi:tin_drome(display_long)|uniprotkb:tin(gene name)|psi-mi:tin(display_short)|uniprotkb:msh2(gene name synonym)|uniprotkb:CG7895(orf name)|uniprotkb:Msh-2(gene name synonym)|uniprotkb:NK-4(gene name synonym) psi-mi:pnr_drome(display_long)|uniprotkb:pnr(gene name)|psi-mi:pnr(display_short)|uniprotkb:GATA-A(gene name synonym)|uniprotkb:CG3978(orf name)|uniprotkb:Transcription factor GATA-A(gene name synonym)|uniprotkb:dGATA-A(gene name synonym)|uniprotkb:Protein pannier(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874064 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524433.1|flybase:FBgn0004110|ensemblmetazoa:FBgn0004110(gene)|ensemblmetazoa:FBtr0084086(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007280"(pole cell migration)|go:"GO:0007419"(ventral cord development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007552"(metamorphosis)|go:"GO:0008354"(germ cell migration)|go:"GO:0008406"(gonad development)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035051"(cardiocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048542"(lymph gland development)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970 refseq:NP_476685.1|flybase:FBgn0003117|ensemblmetazoa:FBgn0003117(gene)|ensemblmetazoa:FBtr0083221(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007510"(cardioblast cell fate determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0022416"(chaeta development)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035051"(cardiocyte differentiation)|go:"GO:0042440"(pigment metabolic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048542"(lymph gland development)|go:"GO:0060047"(heart contraction)|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|reactome:R-DME-5683826|reactome:R-DME-983231 pubmed:11336505(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:5vTbkG0IGgGoekKpC4YuBi2qEfc7227 rogid:G0/pi+DhH2ncsNG77KXtUPOrH7M7227 intact-crc:D03E4F2F3FB3FE34|rigid:AUHHekUXbGlRAl48XXGb8I4aeBo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KJV6 uniprotkb:P40797 intact:EBI-867875 intact:EBI-171301|uniprotkb:Q0E9F5|uniprotkb:Q9V385|ensemblmetazoa:FBpp0087869|ensemblmetazoa:FBpp0087870 psi-mi:q7kjv6_drome(display_long)|uniprotkb:Uba2(gene name)|psi-mi:Uba2(display_short)|uniprotkb:CG7528(orf name) psi-mi:pnut_drome(display_long)|uniprotkb:pnut(gene name)|psi-mi:pnut(display_short)|uniprotkb:CG8705(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874068 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0029113|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033134"(ubiquitin activating enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR019572|interpro:IPR023318|interpro:IPR028077|interpro:IPR030661|interpro:IPR033127|interpro:IPR035985|interpro:IPR042449 refseq:NP_477064.1|refseq:NP_724659.1|flybase:FBgn0013726|dip:DIP-60735N|ensemblmetazoa:FBgn0013726(gene)|ensemblmetazoa:FBtr0088792(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|ensemblmetazoa:FBtr0088793(transcript)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070938"(contractile ring)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0060271"(cilium assembly) pubmed:11884525(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6hSWdsAvG5y2/bW1XcSHzO+1b0A7227 rogid:AwSNOc8ecwdqxwA6z93hfsSa7g87227 intact-crc:6974FF15893E33A9|rigid:Mix6p3PQgp+nstFR65AhYBIiw3g false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9Y103 uniprotkb:P40797 intact:EBI-174432|intact:EBI-501125|uniprotkb:Q9NHN7|ensemblmetazoa:FBpp0078765|ensemblmetazoa:FBpp0311644 intact:EBI-171301|uniprotkb:Q0E9F5|uniprotkb:Q9V385|ensemblmetazoa:FBpp0087869|ensemblmetazoa:FBpp0087870 psi-mi:tfp11_drome(display_long)|uniprotkb:sip1(gene name)|psi-mi:sip1(display_short)|uniprotkb:stip-1(gene name synonym)|uniprotkb:CG7238(orf name)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym) psi-mi:pnut_drome(display_long)|uniprotkb:pnut(gene name)|psi-mi:pnut(display_short)|uniprotkb:CG8705(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874072 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524725.2|flybase:FBgn0024191|refseq:NP_001285636.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|ensemblmetazoa:FBgn0024191(gene)|ensemblmetazoa:FBtr0079134(transcript)|ensemblmetazoa:FBtr0345545(transcript)|go:"GO:0000390"(spliceosomal complex disassembly) refseq:NP_477064.1|refseq:NP_724659.1|flybase:FBgn0013726|dip:DIP-60735N|ensemblmetazoa:FBgn0013726(gene)|ensemblmetazoa:FBtr0088792(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|ensemblmetazoa:FBtr0088793(transcript)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070938"(contractile ring)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0060271"(cilium assembly) pubmed:11884525(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:PJxaiEhZk9uaagQ6GWSK7ryjojU7227 rogid:AwSNOc8ecwdqxwA6z93hfsSa7g87227 intact-crc:E540B56273E63A04|rigid:vHAkAktdwXQPXG+SYL50gi2swKI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P54359 uniprotkb:P40797 intact:EBI-188936|uniprotkb:Q24092|uniprotkb:Q9VDK8|ensemblmetazoa:FBpp0083352 intact:EBI-171301|uniprotkb:Q0E9F5|uniprotkb:Q9V385|ensemblmetazoa:FBpp0087869|ensemblmetazoa:FBpp0087870 psi-mi:sept2_drome(display_long)|uniprotkb:Sep2(gene name)|psi-mi:Sep2(display_short)|uniprotkb:CG4173(orf name) psi-mi:pnut_drome(display_long)|uniprotkb:pnut(gene name)|psi-mi:pnut(display_short)|uniprotkb:CG8705(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874076 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524417.1|flybase:FBgn0014029|dip:DIP-20060N|ensemblmetazoa:FBgn0014029(gene)|ensemblmetazoa:FBtr0083945(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007295"(growth of a germarium-derived egg chamber)|go:"GO:0007349"(cellularization)|go:"GO:0007444"(imaginal disc development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379 refseq:NP_477064.1|refseq:NP_724659.1|flybase:FBgn0013726|dip:DIP-60735N|ensemblmetazoa:FBgn0013726(gene)|ensemblmetazoa:FBtr0088792(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|ensemblmetazoa:FBtr0088793(transcript)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070938"(contractile ring)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0060271"(cilium assembly) pubmed:11884525(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:yZOoGT0rH7z1Sm3rbziG/xiMNMg7227 rogid:AwSNOc8ecwdqxwA6z93hfsSa7g87227 intact-crc:94E2B0CB66752ED9|rigid:440V2BLpAjkIf8B2evbIXdunpxU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42207 uniprotkb:P40797 intact:EBI-120528|uniprotkb:Q9VRH5|uniprotkb:Q8IQ47|ensemblmetazoa:FBpp0076897 intact:EBI-171301|uniprotkb:Q0E9F5|uniprotkb:Q9V385|ensemblmetazoa:FBpp0087869|ensemblmetazoa:FBpp0087870 psi-mi:sept1_drome(display_long)|uniprotkb:DIFF6 protein homolog(gene name synonym)|uniprotkb:Protein innocent bystander(gene name synonym)|uniprotkb:CG1403(orf name)|uniprotkb:Sep1(gene name)|psi-mi:Sep1(display_short)|uniprotkb:Diff6(gene name synonym)|uniprotkb:iby(gene name synonym) psi-mi:pnut_drome(display_long)|uniprotkb:pnut(gene name)|psi-mi:pnut(display_short)|uniprotkb:CG8705(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874080 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0011710(gene)|ensemblmetazoa:FBtr0077198(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0007349"(cellularization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|refseq:NP_523430.1|flybase:FBgn0011710|dip:DIP-18454N refseq:NP_477064.1|refseq:NP_724659.1|flybase:FBgn0013726|dip:DIP-60735N|ensemblmetazoa:FBgn0013726(gene)|ensemblmetazoa:FBtr0088792(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|ensemblmetazoa:FBtr0088793(transcript)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070938"(contractile ring)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0060271"(cilium assembly) pubmed:8590810(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:owbyZvFu8+uF3t60BTm9IqquTL47227 rogid:AwSNOc8ecwdqxwA6z93hfsSa7g87227 intact-crc:6C045A17C4B80110|rigid:OW8cA4njTSjtFZZKOFwW6MnfuyU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40797 uniprotkb:P40797 intact:EBI-171301|uniprotkb:Q0E9F5|uniprotkb:Q9V385|ensemblmetazoa:FBpp0087869|ensemblmetazoa:FBpp0087870 intact:EBI-171301|uniprotkb:Q0E9F5|uniprotkb:Q9V385|ensemblmetazoa:FBpp0087869|ensemblmetazoa:FBpp0087870 psi-mi:pnut_drome(display_long)|uniprotkb:pnut(gene name)|psi-mi:pnut(display_short)|uniprotkb:CG8705(orf name) psi-mi:pnut_drome(display_long)|uniprotkb:pnut(gene name)|psi-mi:pnut(display_short)|uniprotkb:CG8705(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874084 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477064.1|refseq:NP_724659.1|flybase:FBgn0013726|dip:DIP-60735N|ensemblmetazoa:FBgn0013726(gene)|ensemblmetazoa:FBtr0088792(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|ensemblmetazoa:FBtr0088793(transcript)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070938"(contractile ring)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0060271"(cilium assembly) refseq:NP_477064.1|refseq:NP_724659.1|flybase:FBgn0013726|dip:DIP-60735N|ensemblmetazoa:FBgn0013726(gene)|ensemblmetazoa:FBtr0088792(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|ensemblmetazoa:FBtr0088793(transcript)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070938"(contractile ring)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0060271"(cilium assembly) pubmed:11884525(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:AwSNOc8ecwdqxwA6z93hfsSa7g87227 rogid:AwSNOc8ecwdqxwA6z93hfsSa7g87227 intact-crc:76683DCAE6788853|rigid:8dBaaX4jYjxljZFmb3evqjm6i+8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20227 uniprotkb:Q9VH07 intact:EBI-169179|uniprotkb:Q9W2D8|ensemblmetazoa:FBpp0071596 intact:EBI-234957|intact:EBI-867973|uniprotkb:Q9VH06|uniprotkb:Q9NH53|intact:EBI-234969|ensemblmetazoa:FBpp0081704 psi-mi:tbp_drome(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:CG9874(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:ruvb1_drome(display_long)|uniprotkb:pont(gene name)|psi-mi:pont(display_short)|uniprotkb:CG4003(orf name)|uniprotkb:Pontin(gene name synonym)|uniprotkb:Dpontin(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874088 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523805.1|flybase:FBgn0003687|ensemblmetazoa:FBgn0003687(gene)|ensemblmetazoa:FBtr0071679(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519|dip:DIP-80N refseq:NP_652608.1|flybase:FBgn0040078|ensemblmetazoa:FBgn0040078(gene)|ensemblmetazoa:FBtr0082226(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035060"(brahma complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051301"(cell division)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9VH07|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-5696394 pubmed:11080158(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:eRlX8luNoF4M7SFmEnxKSbI6FJo7227 rogid:myRpAnG8tKBHMEnKg+JkpIVkTKg7227 intact-crc:0E0D7911D6DBF5E4|rigid:TmIlwN6yLQXAxk3ETGl8RM63XvU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09615 uniprotkb:Q9VWV9 intact:EBI-98242|uniprotkb:Q27768|uniprotkb:Q27769|uniprotkb:Q8IPI1|uniprotkb:Q8MQP9|uniprotkb:Q9VM27|ensemblmetazoa:FBpp0079060 intact:EBI-176467|uniprotkb:Q94549|ensemblmetazoa:FBpp0074349|ensemblmetazoa:FBpp0302628|ensemblmetazoa:FBpp0305446 psi-mi:wntg_drome(display_long)|uniprotkb:Protein Wnt-1(gene name synonym)|uniprotkb:Protein int-1(gene name synonym)|uniprotkb:CG4889(orf name)|uniprotkb:wg(gene name)|psi-mi:wg(display_short)|uniprotkb:dWnt-1(gene name synonym)|uniprotkb:dInt-1(gene name synonym) psi-mi:porcn_drome(display_long)|uniprotkb:por(gene name)|psi-mi:por(display_short)|uniprotkb:CG6205(orf name)|uniprotkb:porc(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874092 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523502.1|ensemblmetazoa:FBgn0284084(gene)|ensemblmetazoa:FBtr0079432(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007398"(ectoderm development)|go:"GO:0007418"(ventral midline development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007444"(imaginal disc development)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007450"(dorsal/ventral pattern formation, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007523"(larval visceral muscle development)|go:"GO:0007616"(long-term memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010002"(cardioblast differentiation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014019"(neuroblast development)|go:"GO:0016015"(morphogen activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0061328"(posterior Malpighian tubule development)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061332"(Malpighian tubule bud morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR043158|reactome:R-DME-201681|reactome:R-DME-209387|reactome:R-DME-209440|reactome:R-DME-209472|reactome:R-DME-3238698|reactome:R-DME-4086400|reactome:R-DME-4641262|go:"GO:0061320"(pericardial nephrocyte differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032876"(negative regulation of DNA endoreduplication)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035217"(labial disc development)|go:"GO:0035220"(wing disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035263"(genital disc sexually dimorphic development)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035311"(wing cell fate specification)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043195"(terminal bouton)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0046672"(positive regulation of compound eye retinal cell programmed cell death)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048332"(mesoderm morphogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048728"(proboscis development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050808"(synapse organization)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0060061"(Spemann organizer formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060914"(heart formation)|go:"GO:0061316"(canonical Wnt signaling pathway involved in heart development)|go:"GO:0045572"(positive regulation of imaginal disc growth)|flybase:FBgn0284084|dip:DIP-21777N refseq:NP_476890.1|flybase:FBgn0004957|refseq:NP_001259679.1|refseq:NP_001259680.1|ensemblmetazoa:FBgn0004957(gene)|ensemblmetazoa:FBtr0074577(transcript)|ensemblmetazoa:FBtr0310487(transcript)|ensemblmetazoa:FBtr0333247(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006497"(protein lipidation)|go:"GO:0008104"(protein localization)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030258"(lipid modification)|go:"GO:0045234"(protein palmitoleylation)|go:"GO:0051604"(protein maturation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:1990698"(palmitoleoyltransferase activity)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT) pubmed:11821428(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ioGPXpHjZchgMT2/PR2ivC4Jo+s7227 rogid:9Q0bFi2P0V+geNReRTTPoGmbR+Q7227 intact-crc:B368330E7D99243D|rigid:+wWacyUKgZA3mzsXsy5QiBmz4Gs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20659 uniprotkb:P12982 intact:EBI-591327|ensemblmetazoa:FBpp0082406|ensemblmetazoa:FBpp0082409|uniprotkb:Q27255|uniprotkb:Q27327|uniprotkb:Q8INF9|uniprotkb:Q960R2|uniprotkb:Q9VFL1|uniprotkb:A4V2V9|uniprotkb:A4V2W0|intact:EBI-3404288|intact:EBI-3417031|intact:EBI-9922180|intact:EBI-9933604 intact:EBI-152633|uniprotkb:Q4PIY5|uniprotkb:Q9VG75|ensemblmetazoa:FBpp0082067 psi-mi:trx_drome(display_long)|uniprotkb:KMT2A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2A(gene name synonym)|uniprotkb:trx(gene name)|psi-mi:trx(display_short)|uniprotkb:CG8651(orf name)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:pp12_drome(display_long)|uniprotkb:Pp1-87B(gene name)|psi-mi:Pp1-87B(display_short)|uniprotkb:CG5650(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874096 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0003862(gene)|ensemblmetazoa:FBtr0082947(transcript)|ensemblmetazoa:FBtr0082950(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|reactome:R-DME-8936459|reactome:R-DME-8939236|refseq:NP_001014621.1|refseq:NP_476769.1|refseq:NP_476770.1|refseq:NP_599108.1|refseq:NP_599109.1|flybase:FBgn0003862 refseq:NP_524937.1|flybase:FBgn0004103|ensemblmetazoa:FBgn0004103(gene)|ensemblmetazoa:FBtr0082595(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007611"(learning or memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008355"(olfactory learning)|go:"GO:0008542"(visual learning)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0030261"(chromosome condensation)|go:"GO:0040011"(locomotion)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|go:"GO:0005737"(cytoplasm)|reactome:R-DME-350416|reactome:R-DME-350480|reactome:R-DME-538898|go:"GO:0005700"(polytene chromosome)|dip:DIP-18465N pubmed:12524522(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:LDT4/pLaHAuL/kuZMReRH9ZDrNk7227 rogid:wYZDYWZEbdafO7gAM+avnFnIF9Q7227 intact-crc:916A2F1B46671191|rigid:jOq0voCP1w4OdHmaAQ9WUECAgeY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09077 uniprotkb:Q5BIJ2 intact:EBI-666569|uniprotkb:Q23990|uniprotkb:Q24508|uniprotkb:Q9V3Q3|ensemblmetazoa:FBpp0081163|ensemblmetazoa:FBpp0089393 intact:EBI-870570|ensemblmetazoa:FBpp0288758|ensemblmetazoa:FBpp0297601 psi-mi:scr_drome(display_long)|uniprotkb:Scr(gene name)|psi-mi:Scr(display_short)|uniprotkb:CG1030(orf name) psi-mi:q5bij2_drome(display_long)|uniprotkb:CG7901(gene name synonym)|uniprotkb:Dmel\CG7913(gene name synonym)|uniprotkb:PP2A(gene name synonym)|uniprotkb:PP2A B'(gene name synonym)|uniprotkb:PP2A-B(gene name synonym)|uniprotkb:PP2A-B'(gene name synonym)|uniprotkb:PP2A[B'-1](gene name synonym)|uniprotkb:PR61(gene name synonym)|uniprotkb:Wrd(gene name synonym)|uniprotkb:anon-WO0118547.420(gene name synonym)|uniprotkb:dB56-1(gene name synonym)|uniprotkb:dPP2A(gene name synonym)|uniprotkb:dPP2A-B56-1(gene name synonym)|uniprotkb:i234(gene name synonym)|uniprotkb:pp2A-B'(gene name synonym)|uniprotkb:Dmel_CG7913(orf name)|uniprotkb:wrd(gene name)|psi-mi:wrd(display_short)|uniprotkb:B'(gene name synonym)|uniprotkb:B56-1(gene name synonym)|uniprotkb:"BcDNA:GM05554"(gene name synonym)|uniprotkb:CG 7913(gene name synonym)|uniprotkb:CG7913(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874100 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524248.2|refseq:NP_996165.1|flybase:FBgn0003339|dip:DIP-40017N|ensemblmetazoa:FBgn0003339(gene)|ensemblmetazoa:FBtr0081657(transcript)|ensemblmetazoa:FBtr0081658(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007494"(midgut development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045498"(sex comb development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|rcsb pdb:2R5Y|rcsb pdb:2R5Z refseq:NP_001247179.1|refseq:NP_001138070.1|flybase:FBgn0042693|ensemblmetazoa:FBgn0042693(gene)|ensemblmetazoa:FBtr0290319(transcript)|ensemblmetazoa:FBtr0306646(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0097479"(synaptic vesicle localization)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold) pubmed:10856239(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:z5Lj6W1yKerSXCkC3CX96vECd507227 rogid:iS18Ghii8NpF+71yJ+pYXbEkMz07227 intact-crc:F784DD0C930DEF57|rigid:1fFfYsFYT+Y6h77r9c3Rdg+2o34 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P06601 uniprotkb:Q9W214 intact:EBI-254508|uniprotkb:Q9VKB6|ensemblmetazoa:FBpp0079882 intact:EBI-125107|ensemblmetazoa:FBpp0071835|ensemblmetazoa:FBpp0309766 psi-mi:prd_drome(display_long)|uniprotkb:prd(gene name)|psi-mi:prd(display_short)|uniprotkb:CG6716(orf name) psi-mi:q9w214_drome(display_long)|uniprotkb:Ppa(gene name)|psi-mi:Ppa(display_short)|uniprotkb:ppa(gene name synonym)|uniprotkb:Dmel_CG9952(orf name)|uniprotkb:CG9952(orf name)|uniprotkb:Dmel\CG9952(gene name synonym)|uniprotkb:FBXL14(gene name synonym)|uniprotkb:I-55(gene name synonym)|uniprotkb:PPA(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874104 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523556.1|refseq:NP_723721.1|flybase:FBgn0003145|dip:DIP-22888N|ensemblmetazoa:FBgn0003145(gene)|ensemblmetazoa:FBtr0080298(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|rcsb pdb:1FJL|rcsb pdb:1PDN|reactome:R-DME-3214847 refseq:NP_523812.1|flybase:FBgn0020257|refseq:NP_001286743.1|ensemblmetazoa:FBgn0020257(gene)|ensemblmetazoa:FBtr0071924(transcript)|ensemblmetazoa:FBtr0343014(transcript)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR036047 pubmed:11069107(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:hab+069Bmgz4DDY0kUHA+b+hObM7227 rogid:FdHDOn/B7Ywf7t58KemlJYPNfZQ7227 intact-crc:B4DBDE956933E152|rigid:2RvoB5XKXVqjxmRghvF79eC0n30 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20227 uniprotkb:P35820 intact:EBI-169179|uniprotkb:Q9W2D8|ensemblmetazoa:FBpp0071596 intact:EBI-84600|uniprotkb:Q9V6I9|ensemblmetazoa:FBpp0086911|ensemblmetazoa:FBpp0311395|ensemblmetazoa:FBpp0311526 psi-mi:tbp_drome(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:CG9874(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:psc_drome(display_long)|uniprotkb:Psc(gene name)|psi-mi:Psc(display_short)|uniprotkb:Protein posterior sex combs(gene name synonym)|uniprotkb:CG3886(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874108 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523805.1|flybase:FBgn0003687|ensemblmetazoa:FBgn0003687(gene)|ensemblmetazoa:FBtr0071679(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519|dip:DIP-80N refseq:NP_523725.2|flybase:FBgn0005624|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0007419"(ventral cord development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-DME-3108214|reactome:R-DME-3899300|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724|reactome:R-DME-8953750|interpro:IPR001841(Zinc finger, RING-type)|ensemblmetazoa:FBgn0005624(gene)|ensemblmetazoa:FBtr0087798(transcript)|ensemblmetazoa:FBtr0345196(transcript)|ensemblmetazoa:FBtr0345375(transcript)|refseq:NP_001286368.1|refseq:NP_001286369.1 pubmed:11493925(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:eRlX8luNoF4M7SFmEnxKSbI6FJo7227 rogid:C0LCX+uqZs0r5z4fFql91xQXLNs7227 intact-crc:D15A8A8D18512BE8|rigid:wRUJlx+YsT/Y2cKNFSp2HKHErjQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P47825 uniprotkb:P35820 intact:EBI-277958|uniprotkb:P49845|uniprotkb:Q0E8E3|uniprotkb:Q1LZ31|uniprotkb:Q8T9E0|uniprotkb:Q9VUY7|ensemblmetazoa:FBpp0075205|ensemblmetazoa:FBpp0075206|ensemblmetazoa:FBpp0291125|ensemblmetazoa:FBpp0311865 intact:EBI-84600|uniprotkb:Q9V6I9|ensemblmetazoa:FBpp0086911|ensemblmetazoa:FBpp0311395|ensemblmetazoa:FBpp0311526 psi-mi:taf4_drome(display_long)|uniprotkb:Transcription initiation factor TFIID 110 kDa subunit(gene name synonym)|uniprotkb:110 kDa TBP-associated factor(gene name synonym)|uniprotkb:Taf4(gene name)|psi-mi:Taf4(display_short)|uniprotkb:TAF110(gene name synonym)|uniprotkb:CG5444(orf name) psi-mi:psc_drome(display_long)|uniprotkb:Psc(gene name)|psi-mi:Psc(display_short)|uniprotkb:Protein posterior sex combs(gene name synonym)|uniprotkb:CG3886(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874112 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_788511.1|refseq:NP_996101.1|flybase:FBgn0010280|refseq:NP_001287077.1|refseq:NP_001163453.1|refseq:NP_524102.1|refseq:NP_730109.1|dip:DIP-237N|ensemblmetazoa:FBgn0010280(gene)|ensemblmetazoa:FBtr0075448(transcript)|ensemblmetazoa:FBtr0075449(transcript)|ensemblmetazoa:FBtr0301911(transcript)|ensemblmetazoa:FBtr0345951(transcript)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR007900(Transcription initiation factor TFIID component TAF4)|interpro:IPR009072(Histone-fold)|interpro:IPR037249|mint:P47825|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 refseq:NP_523725.2|flybase:FBgn0005624|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0007419"(ventral cord development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-DME-3108214|reactome:R-DME-3899300|reactome:R-DME-4570464|reactome:R-DME-8939243|reactome:R-DME-8943724|reactome:R-DME-8953750|interpro:IPR001841(Zinc finger, RING-type)|ensemblmetazoa:FBgn0005624(gene)|ensemblmetazoa:FBtr0087798(transcript)|ensemblmetazoa:FBtr0345196(transcript)|ensemblmetazoa:FBtr0345375(transcript)|refseq:NP_001286368.1|refseq:NP_001286369.1 pubmed:11493925(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KMwgcLywcp/YxxTLBjtmqXNPhdo7227 rogid:C0LCX+uqZs0r5z4fFql91xQXLNs7227 intact-crc:6AB3998B1CCAA0C8|rigid:ILfWyGgUH26dYrt8gzBoACKRn+E false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q08605 uniprotkb:Q24455 intact:EBI-300317|uniprotkb:Q08083|uniprotkb:Q7JN57|uniprotkb:Q8MYL3|uniprotkb:Q8T387|uniprotkb:Q9V3X7|uniprotkb:Q9VUH2|uniprotkb:O18349|uniprotkb:O18350|uniprotkb:O18526 intact:EBI-870579|uniprotkb:Q24003|uniprotkb:Q24456 psi-mi:gaga_drome(display_long)|uniprotkb:Trl(gene name)|psi-mi:Trl(display_short)|uniprotkb:GAGA(gene name synonym)|uniprotkb:TFGAGA(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:GAGA factor(gene name synonym)|uniprotkb:Adh transcription factor 2(gene name synonym)|uniprotkb:Neural conserved at 70F(gene name synonym)|uniprotkb:Adf-2(gene name synonym)|uniprotkb:Nc70F(gene name synonym)|uniprotkb:CG33261(orf name) psi-mi:q24455_drome(display_long)|uniprotkb:psq(gene name)|psi-mi:psq(display_short)|uniprotkb:pipsqueak(gene name synonym)|uniprotkb:CG2368(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874116 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000280"(nuclear division)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007549"(dosage compensation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0034728"(nucleosome organization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051301"(cell division)|go:"GO:1901409"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:1990000"(amyloid fibril formation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR015318(Zinc finger, GAGAG binding factor)|rcsb pdb:1YUI|rcsb pdb:1YUJ|go:"GO:0035075"(response to ecdysone)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043044"|refseq:NP_001034014.1|refseq:NP_996077.1|refseq:NP_996078.1|refseq:NP_996079.1|refseq:NP_996080.1|refseq:NP_996081.1|refseq:NP_996082.1|flybase:FBgn0013263 flybase:FBgn0263102|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0031935"(obsolete regulation of chromatin silencing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold) pubmed:12271134(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:s2lpiYJCLr9x3aKiQRvlG3gE9nk7227 rogid:DXnxDxFMiw36et8y8J90GQVaaUQ7227 intact-crc:0E109BA2992C5E4A|rigid:97cNNXqa6cnr9tTUOuyQ2EgZtvw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24298 uniprotkb:P35992 intact:EBI-112930|uniprotkb:Q9W2N1|ensemblmetazoa:FBpp0071475 intact:EBI-675831|uniprotkb:A4V4B4|uniprotkb:Q0KHT5|uniprotkb:Q86NN9|uniprotkb:Q8IR87|uniprotkb:Q9VYW1|uniprotkb:B7Z142|uniprotkb:F0JAM3|uniprotkb:M9PEB6|uniprotkb:M9PJI5|intact:EBI-675858|ensemblmetazoa:FBpp0303418|ensemblmetazoa:FBpp0303419 psi-mi:cade_drome(display_long)|uniprotkb:shg(gene name)|psi-mi:shg(display_short)|uniprotkb:Protein shotgun(gene name synonym)|uniprotkb:CG3722(orf name)|uniprotkb:E-cadherin(gene name synonym) psi-mi:ptp10_drome(display_long)|uniprotkb:Receptor-linked protein-tyrosine phosphatase 10D(gene name synonym)|uniprotkb:Ptp10D(gene name)|psi-mi:Ptp10D(display_short)|uniprotkb:CG1817(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874120 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476722.1|flybase:FBgn0003391|dip:DIP-22198N|ensemblmetazoa:FBgn0003391(gene)|ensemblmetazoa:FBtr0071546(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001748"(insect visual primordium development)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005914"(spot adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007281"(germ cell development)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007379"(segment specification)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008258"(head involution)|go:"GO:0008354"(germ cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008406"(gonad development)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0017022"(myosin binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043296"(apical junction complex)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045176"(apical protein localization)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0048477"(oogenesis)|go:"GO:0050832"(defense response to fungus)|go:"GO:0055037"(recycling endosome)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098730"(male germline stem cell symmetric division)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397 refseq:NP_996413.2|refseq:NP_996414.2|refseq:NP_001138187.1|refseq:NP_727544.2|flybase:FBgn0004370|refseq:NP_001259453.1|refseq:NP_001259454.1|ensemblmetazoa:FBgn0004370(gene)|ensemblmetazoa:FBtr0330392(transcript)|ensemblmetazoa:FBtr0330393(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007411"(axon guidance)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007616"(long-term memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045177"(apical part of cell)|go:"GO:0060446"(branching involved in open tracheal system development)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|rcsb pdb:3S3E|rcsb pdb:3S3F|rcsb pdb:3S3H|rcsb pdb:3S3K|reactome:R-DME-6798695|go:"GO:0007417"(central nervous system development) pubmed:7961789(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2015/01/16 rogid:BEKC07n+twCk47JtwWbhQbw1cs87227 rogid:H4TeAMfu/3+wXdDaclgyUv2rLTk7227 intact-crc:D12DD7F9B04C1C3D|rigid:72+NMH3bA1M2nOWBy5fZzhHvcBY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P40417 uniprotkb:Q9W2F3 intact:EBI-867790|uniprotkb:A0A021WW06|uniprotkb:Q7PL59|uniprotkb:Q9W5M2|uniprotkb:A8Y4W1|uniprotkb:A8Y4W2|uniprotkb:Q9W5M3|ensemblmetazoa:FBpp0112423|ensemblmetazoa:FBpp0112425|ensemblmetazoa:FBpp0112426|ensemblmetazoa:FBpp0311493 intact:EBI-109743|uniprotkb:Q9Y0X8|ensemblmetazoa:FBpp0071603 psi-mi:erka_drome(display_long)|uniprotkb:Extracellular-regulated kinase A(gene name synonym)|uniprotkb:Protein rolled(gene name synonym)|uniprotkb:rl(gene name)|psi-mi:rl(display_short)|uniprotkb:ERKa(gene name synonym)|uniprotkb:CG12559(orf name)|uniprotkb:MAPK(gene name synonym) psi-mi:q9w2f3_drome(display_long)|uniprotkb:PTP-ER(gene name)|psi-mi:PTP-ER(display_short)|uniprotkb:Dmel\CG9856(gene name synonym)|uniprotkb:ER2-5(gene name synonym)|uniprotkb:ptp-er(gene name synonym)|uniprotkb:CG9856(orf name)|uniprotkb:Dmel_CG9856(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874124 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001015121.3|refseq:NP_001104348.2|refseq:NP_001287635.1|refseq:NP_001015122.1|refseq:NP_001015123.1|refseq:NP_001104349.1|flybase:FBgn0003256|dip:DIP-17266N|ensemblmetazoa:FBgn0003256(gene)|ensemblmetazoa:FBtr0113700(transcript)|ensemblmetazoa:FBtr0113702(transcript)|ensemblmetazoa:FBtr0113703(transcript)|ensemblmetazoa:FBtr0345337(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007362"(terminal region determination)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000826"(regulation of heart morphogenesis)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P40417|reactome:R-DME-110056|reactome:R-DME-112409|reactome:R-DME-112411|reactome:R-DME-1295596|reactome:R-DME-162658|reactome:R-DME-170968|reactome:R-DME-198753|reactome:R-DME-202670|reactome:R-DME-2029482|reactome:R-DME-2559580|reactome:R-DME-2559582|reactome:R-DME-2559585|reactome:R-DME-2871796|reactome:R-DME-3371453|reactome:R-DME-375165|reactome:R-DME-437239|reactome:R-DME-445144|reactome:R-DME-450341|reactome:R-DME-456926|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5654733|reactome:R-DME-5663213|reactome:R-DME-5673001|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5687128|reactome:R-DME-6798695|reactome:R-DME-74749|reactome:R-DME-881907|reactome:R-DME-9634635|reactome:R-DME-9634638 refseq:NP_726092.1|flybase:FBgn0016641|ensemblmetazoa:FBgn0016641(gene)|ensemblmetazoa:FBtr0071686(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0033549"(MAP kinase phosphatase activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|reactome:R-DME-5675221 pubmed:12810595(see-also)|pubmed:7697720(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:m7w7KhuZSyx3t+dR2TKtvx/vRtA7227 rogid:B4B6eS7NtII+DZNKFFyMsOQOrMc7227 intact-crc:97908989C3932B91|rigid:MSuJz9MsJjk3grYVzIFDypKKcVg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24229 uniprotkb:O96660 intact:EBI-869214 intact:EBI-145058|ensemblmetazoa:FBpp0071140|ensemblmetazoa:FBpp0309145 psi-mi:q24229_drome(display_long)|uniprotkb:put(gene name)|psi-mi:put(display_short)|uniprotkb:CG7904(orf name) psi-mi:o96660_drome(display_long)|uniprotkb:Smox(gene name)|psi-mi:Smox(display_short)|uniprotkb:smad2(gene name synonym)|uniprotkb:CG2262(orf name)|uniprotkb:SMAD family member(gene name synonym)|uniprotkb:DSMAD2(gene name synonym)|uniprotkb:DSmad2(gene name synonym)|uniprotkb:Dmel\CG2262(gene name synonym)|uniprotkb:SMAD2(gene name synonym)|uniprotkb:SMOX(gene name synonym)|uniprotkb:Sad(gene name synonym)|uniprotkb:Smad(gene name synonym)|uniprotkb:Smad2(gene name synonym)|uniprotkb:SmoX(gene name synonym)|uniprotkb:dSMAD2(gene name synonym)|uniprotkb:dSmad2(gene name synonym)|uniprotkb:dsmad2(gene name synonym)|uniprotkb:"l(1)G0348"(gene name synonym)|uniprotkb:sad(gene name synonym)|uniprotkb:smox(gene name synonym)|uniprotkb:ted(gene name synonym)|uniprotkb:tmp(gene name synonym)|uniprotkb:Dmel_CG2262(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874128 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0003169|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007391"(dorsal closure)|go:"GO:0007411"(axon guidance)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007428"(primary branching, open tracheal system)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0008258"(head involution)|go:"GO:0017002"(activin-activated receptor activity)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0046872"(metal ion binding)|go:"GO:0048179"(activin receptor complex)|go:"GO:0048185"(activin binding)|go:"GO:0048666"(neuron development)|interpro:IPR000333(Activin type II receptor)|interpro:IPR000472(TGF-beta receptor/activin receptor, type I/II)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like) refseq:NP_511079.1|flybase:FBgn0025800|refseq:NP_001285006.1|ensemblmetazoa:FBgn0025800(gene)|ensemblmetazoa:FBtr0071192(transcript)|ensemblmetazoa:FBtr0340159(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010507"(negative regulation of autophagy)|dip:DIP-18259N|go:"GO:0016319"(mushroom body development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0044719"(regulation of imaginal disc-derived wing size)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048666"(neuron development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090256"(regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|reactome:R-DME-1181150|reactome:R-DME-1502540|reactome:R-DME-2173788|reactome:R-DME-2173789|reactome:R-DME-2173795|reactome:R-DME-2173796|reactome:R-DME-8941855|reactome:R-DME-9617828 pubmed:10320478(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:m+Pexdc07PthjexkqjIsK/JHstk7227 rogid:Yp3zkP2CIw7h2/zcG0RD6D6JivE7227 intact-crc:A2D9D2BF52D78E1E|rigid:hEcp7o2K+6XUvCERmsshV/D7n40 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KTI7 uniprotkb:Q9BLX1 intact:EBI-870609|ensemblmetazoa:FBpp0304690 intact:EBI-870594|ensemblmetazoa:FBpp0290881 psi-mi:q7kti7_drome(display_long)|uniprotkb:Pvr(gene name)|psi-mi:Pvr(display_short)|uniprotkb:8222(gene name synonym)|uniprotkb:CT24332(gene name synonym)|uniprotkb:DmVEGFR(gene name synonym)|uniprotkb:Dmel\CG8222(gene name synonym)|uniprotkb:PVR(gene name synonym)|uniprotkb:VEGFR(gene name synonym)|uniprotkb:VEGFR-A(gene name synonym)|uniprotkb:VGR1(gene name synonym)|uniprotkb:Vegf(gene name synonym)|uniprotkb:Vegfr(gene name synonym)|uniprotkb:Vegfr-b(gene name synonym)|uniprotkb:Vegfr-c(gene name synonym)|uniprotkb:Vgr1(gene name synonym)|uniprotkb:pvr(gene name synonym)|uniprotkb:stai(gene name synonym)|uniprotkb:vgr1(gene name synonym)|uniprotkb:Dmel_CG8222(orf name)|uniprotkb:PvR(gene name synonym)|uniprotkb:CG8222(orf name) psi-mi:q9blx1_drome(display_long)|uniprotkb:Dmel_CG7103(orf name)|uniprotkb:DmVEGF-1(gene name synonym)|uniprotkb:Dmel\CG7103(gene name synonym)|uniprotkb:EP1624(gene name synonym)|uniprotkb:PVF(gene name synonym)|uniprotkb:PVF1(gene name synonym)|uniprotkb:PVFs(gene name synonym)|uniprotkb:Pvf(gene name synonym)|uniprotkb:VEGF(gene name synonym)|uniprotkb:VEGF2-B(gene name synonym)|uniprotkb:Vegf17E(gene name synonym)|uniprotkb:Vegf17e-a(gene name synonym)|uniprotkb:"l(1)G0146"(gene name synonym)|uniprotkb:pvf1(gene name synonym)|uniprotkb:vegf1(gene name synonym)|uniprotkb:Pvf1(gene name)|psi-mi:Pvf1(display_short)|uniprotkb:Vegf17e-b(gene name synonym)|uniprotkb:Pvf-1(gene name synonym)|uniprotkb:CG7103(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874132 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_995647.2|flybase:FBgn0032006|ensemblmetazoa:FBgn0032006(gene)|ensemblmetazoa:FBtr0332417(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007419"(ventral cord development)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030097"(hemopoiesis)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0043235"(receptor complex)|go:"GO:0045087"(innate immune response)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0061327"(anterior Malpighian tubule development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036179 refseq:NP_001162792.1|flybase:FBgn0030964|ensemblmetazoa:FBgn0030964(gene)|ensemblmetazoa:FBtr0301667(transcript)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030031"(cell projection assembly)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0035099"(hemocyte migration)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061327"(anterior Malpighian tubule development)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000683"(regulation of cellular response to X-ray)|interpro:IPR000072("Platelet-derived growth factor (PDGF)")|interpro:IPR029034 pubmed:11595182(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:M53rxr0LapRVqRBJsScUgmHs3RM7227 rogid:NzMe6qroSRjcktTg/+VEX53M8Wk7227 intact-crc:76E537DCA3F1A00D|rigid:tz57uX3fxIbL6B7Gpl2Pzm3bKCo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q86BI2 uniprotkb:P08645 intact:EBI-118360|ensemblmetazoa:FBpp0075536|ensemblmetazoa:FBpp0075537|ensemblmetazoa:FBpp0075538 intact:EBI-175963|uniprotkb:Q2XYB6|uniprotkb:Q540V3|uniprotkb:Q9V3N0|ensemblmetazoa:FBpp0072746|ensemblmetazoa:FBpp0292253|ensemblmetazoa:FBpp0304917 psi-mi:q86bi2_drome(display_long)|uniprotkb:Rgl(gene name)|psi-mi:Rgl(display_short)|uniprotkb:Rgl-RC(gene name synonym)|uniprotkb:DRgl(gene name synonym)|uniprotkb:Dmel\CG8865(gene name synonym)|uniprotkb:RalGDS(gene name synonym)|uniprotkb:RasGDS(gene name synonym)|uniprotkb:dRGL(gene name synonym)|uniprotkb:rgl(gene name synonym)|uniprotkb:Dmel_CG8865(orf name)|uniprotkb:CG8865(orf name) psi-mi:rap1_drome(display_long)|uniprotkb:Rap1(gene name)|psi-mi:Rap1(display_short)|uniprotkb:R(gene name synonym)|uniprotkb:RAP(gene name synonym)|uniprotkb:Rap1 GTPase(gene name synonym)|uniprotkb:Ras-like protein 3(gene name synonym)|uniprotkb:ras3(gene name synonym)|uniprotkb:CG1956(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874136 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0026376(gene)|ensemblmetazoa:FBtr0075794(transcript)|ensemblmetazoa:FBtr0075795(transcript)|ensemblmetazoa:FBtr0075796(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000159(Ras-association)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036964|refseq:NP_788503.1|refseq:NP_788504.1|refseq:NP_788505.1|flybase:FBgn0026376 refseq:NP_001189023.1|refseq:NP_476857.1|flybase:FBgn0004636|refseq:NP_001261295.1|ensemblmetazoa:FBgn0004636(gene)|ensemblmetazoa:FBtr0072867(transcript)|ensemblmetazoa:FBtr0303154(transcript)|ensemblmetazoa:FBtr0332671(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031252"(cell leading edge)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0045874"(positive regulation of sevenless signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR038851|reactome:R-DME-170968|reactome:R-DME-354192|reactome:R-DME-381676|reactome:R-DME-392517|reactome:R-DME-5674135|reactome:R-DME-6798695 pubmed:12529414(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:tdkQt55BAwB2gJNFoUBO70r9ZHw7227 rogid:mu2X455U2/v4pF+nXz0kpjvYiA07227 intact-crc:05955AB6E5C8CA12|rigid:z8gVJ2CUUJwrAi4Nd7B30LAmLIA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P04950 uniprotkb:O18334 intact:EBI-173431|uniprotkb:Q9TX53|ensemblmetazoa:FBpp0083284 intact:EBI-119040|ensemblmetazoa:FBpp0079943|ensemblmetazoa:FBpp0312096 psi-mi:ops3_drome(display_long)|uniprotkb:Rh3(gene name)|psi-mi:Rh3(display_short)|uniprotkb:RH92CD(gene name synonym)|uniprotkb:CG10888(orf name)|uniprotkb:Inner R7 photoreceptor cells opsin(gene name synonym) psi-mi:rab6_drome(display_long)|uniprotkb:Rab6(gene name)|psi-mi:Rab6(display_short)|uniprotkb:Protein warthog(gene name synonym)|uniprotkb:wrt(gene name synonym)|uniprotkb:CG6601(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874140 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524411.1|flybase:FBgn0003249|ensemblmetazoa:FBgn0003249(gene)|ensemblmetazoa:FBtr0083876(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007604"(phototransduction, UV)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0009589"(detection of UV)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016039"(absorption of UV light)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000856(Opsin RH3/RH4)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR027430 refseq:NP_477172.1|flybase:FBgn0015797|ensemblmetazoa:FBgn0015797(gene)|ensemblmetazoa:FBtr0080361(transcript)|ensemblmetazoa:FBtr0346437(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001881"(receptor recycling)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007411"(axon guidance)|go:"GO:0007602"(phototransduction)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0045467"(R7 cell development)|go:"GO:0050832"(defense response to fungus)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2Y8E|reactome:R-DME-6798695|reactome:R-DME-6811436|reactome:R-DME-6811438|reactome:R-DME-8854214|reactome:R-DME-8873719|refseq:NP_001285869.1 pubmed:9685396(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:J9t/dooebl4Vl/i5Zn4m8AujxUU7227 rogid:grzQGQnU52XKBE9V1l6qulbl4xs7227 intact-crc:E7162E9ACBB3D7B2|rigid:Leqj+PsL2KH7PIpjNGRwDt0vSFE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9NHV9 uniprotkb:P40792 intact:EBI-87115|uniprotkb:A2RVJ3|uniprotkb:A4V4R6|uniprotkb:Q8SWT3|uniprotkb:Q8T061|uniprotkb:Q9VWJ5|ensemblmetazoa:FBpp0074448|ensemblmetazoa:FBpp0074449 intact:EBI-74845|uniprotkb:Q9W0H7|ensemblmetazoa:FBpp0072614|ensemblmetazoa:FBpp0304252 psi-mi:vav_drome(display_long)|uniprotkb:Vav(gene name)|psi-mi:Vav(display_short)|uniprotkb:CG7893(orf name) psi-mi:rac1_drome(display_long)|uniprotkb:Rac1(gene name)|psi-mi:Rac1(display_short)|uniprotkb:RacA(gene name synonym)|uniprotkb:CG2248(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874144 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|ensemblmetazoa:FBgn0040068(gene)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007520"(myoblast fusion)|ensemblmetazoa:FBtr0074677(transcript)|go:"GO:0016477"(cell migration)|ensemblmetazoa:FBtr0074678(transcript)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903391"(regulation of adherens junction organization)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|reactome:R-DME-114604|reactome:R-DME-1257604|reactome:R-DME-1433557|reactome:R-DME-193648|reactome:R-DME-2871796|reactome:R-DME-2871809|reactome:R-DME-3928665|reactome:R-DME-416482|reactome:R-DME-4420097|reactome:R-DME-445144|reactome:R-DME-512988|reactome:R-DME-6811558|reactome:R-DME-8980692|reactome:R-DME-9013148|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-9027284|reactome:R-DME-912631|reactome:R-DME-5218920|reactome:R-DME-983695|refseq:NP_573372.1|refseq:NP_728235.1|flybase:FBgn0040068 refseq:NP_476950.1|flybase:FBgn0010333|refseq:NP_001261247.1|ensemblmetazoa:FBgn0010333(gene)|ensemblmetazoa:FBtr0072730(transcript)|ensemblmetazoa:FBtr0331868(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002433"(immune response-regulating cell surface receptor signaling pathway involved in phagocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007394"(dorsal closure, elongation of leading edge cells)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007516"(hemocyte development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007613"(memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008258"(head involution)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0016028"(rhabdomere)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016203"(muscle attachment)|go:"GO:0016358"(dendrite development)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035010"(encapsulation of foreign target)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0035320"(imaginal disc-derived wing hair site selection)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048675"(axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0055001"(muscle cell development)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097206"(nephrocyte filtration)|go:"GO:0110125"(negative regulation of myotube cell migration)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1903391"(regulation of adherens junction organization)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-1433557|reactome:R-DME-193648|reactome:R-DME-2029482|reactome:R-DME-2871796|reactome:R-DME-350376|reactome:R-DME-376172|reactome:R-DME-389359|reactome:R-DME-3928662|reactome:R-DME-3928664|reactome:R-DME-3928665|reactome:R-DME-399954|reactome:R-DME-4086400|reactome:R-DME-4420097|reactome:R-DME-445144|reactome:R-DME-5218920|reactome:R-DME-5625740|reactome:R-DME-5627123|reactome:R-DME-5663213|reactome:R-DME-5687128|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-9013407|reactome:R-DME-9706019|reactome:R-DME-983231 pubmed:14555990(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Rqb6Z6ol9LlplBYK2DZaiFIPwYo7227 rogid:nVrsdRuWmYjJp67rd4Es0mFDuUU7227 intact-crc:55D5905DE2BB1364|rigid:t7FBrd4ZAp7c4dMY2PEqMTUY0tw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9U1K1 uniprotkb:P40792 intact:EBI-91672|intact:EBI-867570|intact:EBI-499570|uniprotkb:Q9VIN3|uniprotkb:Q9VIN4|uniprotkb:Q5U0Z8|uniprotkb:Q8INV3|uniprotkb:Q8INV4|uniprotkb:Q8INV5|uniprotkb:Q8SXP3|uniprotkb:Q8T8P8|uniprotkb:Q9U4F0|uniprotkb:Q9U4F1|ensemblmetazoa:FBpp0080884 intact:EBI-74845|uniprotkb:Q9W0H7|ensemblmetazoa:FBpp0072614|ensemblmetazoa:FBpp0304252 psi-mi:spir_drome(display_long)|uniprotkb:spir(gene name)|psi-mi:spir(display_short)|uniprotkb:p150-Spir(gene name synonym)|uniprotkb:CG10076(orf name) psi-mi:rac1_drome(display_long)|uniprotkb:Rac1(gene name)|psi-mi:Rac1(display_short)|uniprotkb:RacA(gene name synonym)|uniprotkb:CG2248(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874148 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001286100.1|refseq:NP_524854.2|refseq:NP_724254.1|refseq:NP_724255.1|refseq:NP_724256.2|flybase:FBgn0003475|ensemblmetazoa:FBgn0003475(gene)|ensemblmetazoa:FBtr0081352(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046907"(intracellular transport)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0048477"(oogenesis)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0007316"(pole plasm RNA localization)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051639"(actin filament network formation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011019(KIND)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030029"(actin filament-based process)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0030036"(actin cytoskeleton organization)|interpro:IPR029901|rcsb pdb:3MMV|rcsb pdb:3MN5|rcsb pdb:3MN6|rcsb pdb:3MN7|rcsb pdb:3MN9|rcsb pdb:3UE5|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030717"(oocyte karyosome formation)|rcsb pdb:4EFH|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045010"(actin nucleation)|refseq:NP_001246102.1|dip:DIP-17301N refseq:NP_476950.1|flybase:FBgn0010333|refseq:NP_001261247.1|ensemblmetazoa:FBgn0010333(gene)|ensemblmetazoa:FBtr0072730(transcript)|ensemblmetazoa:FBtr0331868(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002433"(immune response-regulating cell surface receptor signaling pathway involved in phagocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007394"(dorsal closure, elongation of leading edge cells)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007516"(hemocyte development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007613"(memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008258"(head involution)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0016028"(rhabdomere)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016203"(muscle attachment)|go:"GO:0016358"(dendrite development)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035010"(encapsulation of foreign target)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0035320"(imaginal disc-derived wing hair site selection)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048675"(axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0055001"(muscle cell development)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097206"(nephrocyte filtration)|go:"GO:0110125"(negative regulation of myotube cell migration)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1903391"(regulation of adherens junction organization)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-1433557|reactome:R-DME-193648|reactome:R-DME-2029482|reactome:R-DME-2871796|reactome:R-DME-350376|reactome:R-DME-376172|reactome:R-DME-389359|reactome:R-DME-3928662|reactome:R-DME-3928664|reactome:R-DME-3928665|reactome:R-DME-399954|reactome:R-DME-4086400|reactome:R-DME-4420097|reactome:R-DME-445144|reactome:R-DME-5218920|reactome:R-DME-5625740|reactome:R-DME-5627123|reactome:R-DME-5663213|reactome:R-DME-5687128|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-9013407|reactome:R-DME-9706019|reactome:R-DME-983231 pubmed:10556052(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:d5/uax72i+0dvjWvfORgiCSMjwQ7227 rogid:nVrsdRuWmYjJp67rd4Es0mFDuUU7227 intact-crc:6DF97D3993289E2A|rigid:jz2Ed8TvZn2V3X229ncPEKjucXI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P48555 uniprotkb:Q9VDG2 intact:EBI-115197|uniprotkb:Q540X1|ensemblmetazoa:FBpp0070558|ensemblmetazoa:FBpp0070559|uniprotkb:Q9W4Q6 intact:EBI-173258|uniprotkb:O96392|uniprotkb:Q8MZ58|ensemblmetazoa:FBpp0083406 psi-mi:rala_drome(display_long)|uniprotkb:Rala(gene name)|psi-mi:Rala(display_short)|uniprotkb:CG2849(orf name) psi-mi:rlip_drome(display_long)|uniprotkb:Rlip(gene name)|psi-mi:Rlip(display_short)|uniprotkb:CG11622(orf name)|uniprotkb:Ral-interacting protein 1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0015286(gene)|ensemblmetazoa:FBtr0070583(transcript)|ensemblmetazoa:FBtr0070584(transcript)|go:"GO:0003924"(GTPase activity)|rcsb pdb:5CM9|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0019003"(GDP binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0090543"(Flemming body)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|rcsb pdb:5CM8|refseq:NP_525063.1|refseq:NP_726882.1|flybase:FBgn0015286|dip:DIP-19199N refseq:NP_650933.2|flybase:FBgn0026056|ensemblmetazoa:FBgn0026056(gene)|ensemblmetazoa:FBtr0084002(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046578"(regulation of Ras protein signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|reactome:R-DME-9013148|reactome:R-DME-9013149 pubmed:10910768(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:sTSyV5P4zR3/IGjwg6Ov0YFUl6g7227 rogid:yFklQl4olbZi9X62QgjH3VbyGzE7227 intact-crc:10EA82F088D2099F|rigid:uEUb/livAr9lBEti/53e/TmhCzk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q86BI2 uniprotkb:P48555 intact:EBI-118360|ensemblmetazoa:FBpp0075536|ensemblmetazoa:FBpp0075537|ensemblmetazoa:FBpp0075538 intact:EBI-115197|uniprotkb:Q540X1|ensemblmetazoa:FBpp0070558|ensemblmetazoa:FBpp0070559|uniprotkb:Q9W4Q6 psi-mi:q86bi2_drome(display_long)|uniprotkb:Rgl(gene name)|psi-mi:Rgl(display_short)|uniprotkb:Rgl-RC(gene name synonym)|uniprotkb:DRgl(gene name synonym)|uniprotkb:Dmel\CG8865(gene name synonym)|uniprotkb:RalGDS(gene name synonym)|uniprotkb:RasGDS(gene name synonym)|uniprotkb:dRGL(gene name synonym)|uniprotkb:rgl(gene name synonym)|uniprotkb:Dmel_CG8865(orf name)|uniprotkb:CG8865(orf name) psi-mi:rala_drome(display_long)|uniprotkb:Rala(gene name)|psi-mi:Rala(display_short)|uniprotkb:CG2849(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874156 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0026376(gene)|ensemblmetazoa:FBtr0075794(transcript)|ensemblmetazoa:FBtr0075795(transcript)|ensemblmetazoa:FBtr0075796(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000159(Ras-association)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036964|refseq:NP_788503.1|refseq:NP_788504.1|refseq:NP_788505.1|flybase:FBgn0026376 ensemblmetazoa:FBgn0015286(gene)|ensemblmetazoa:FBtr0070583(transcript)|ensemblmetazoa:FBtr0070584(transcript)|go:"GO:0003924"(GTPase activity)|rcsb pdb:5CM9|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007464"(R3/R4 cell fate commitment)|go:"GO:0019003"(GDP binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0090543"(Flemming body)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|rcsb pdb:5CM8|refseq:NP_525063.1|refseq:NP_726882.1|flybase:FBgn0015286|dip:DIP-19199N pubmed:10427090(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:tdkQt55BAwB2gJNFoUBO70r9ZHw7227 rogid:sTSyV5P4zR3/IGjwg6Ov0YFUl6g7227 intact-crc:A9A8A1C78C43FEE5|rigid:vydgU4K8zK63qkCkES7dC3lnFi0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09077 uniprotkb:P08646 intact:EBI-666569|uniprotkb:Q23990|uniprotkb:Q24508|uniprotkb:Q9V3Q3|ensemblmetazoa:FBpp0081163|ensemblmetazoa:FBpp0089393 intact:EBI-119517|uniprotkb:Q9V448|ensemblmetazoa:FBpp0081600 psi-mi:scr_drome(display_long)|uniprotkb:Scr(gene name)|psi-mi:Scr(display_short)|uniprotkb:CG1030(orf name) psi-mi:ras1_drome(display_long)|uniprotkb:Ras85D(gene name)|psi-mi:Ras85D(display_short)|uniprotkb:Ras1(gene name synonym)|uniprotkb:CG9375(orf name)|uniprotkb:Dmras85D(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874160 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524248.2|refseq:NP_996165.1|flybase:FBgn0003339|dip:DIP-40017N|ensemblmetazoa:FBgn0003339(gene)|ensemblmetazoa:FBtr0081657(transcript)|ensemblmetazoa:FBtr0081658(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007494"(midgut development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045498"(sex comb development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|rcsb pdb:2R5Y|rcsb pdb:2R5Z refseq:NP_476699.1|flybase:FBgn0003205|ensemblmetazoa:FBgn0003205(gene)|ensemblmetazoa:FBtr0082122(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0001709"(cell fate determination)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0002168"(instar larval development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0019003"(GDP binding)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0000165"(MAPK cascade)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0040008"(regulation of growth)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0051607"(defense response to virus)|go:"GO:0060438"(trachea development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072002"(Malpighian tubule development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-DME-1250347|reactome:R-DME-1433557|reactome:R-DME-171007|reactome:R-DME-179812|reactome:R-DME-180336|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2871796|reactome:R-DME-375165|reactome:R-DME-3928662|reactome:R-DME-4086398|reactome:R-DME-432553|reactome:R-DME-5218921|reactome:R-DME-5621575|reactome:R-DME-5654688|reactome:R-DME-5654693|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5673000|reactome:R-DME-5673001|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-8951936|reactome:R-DME-9607240|reactome:R-DME-9634635|reactome:R-DME-9648002|dip:DIP-23541N pubmed:9178011(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:z5Lj6W1yKerSXCkC3CX96vECd507227 rogid:+9A4GDDFmYKN5famfgTGA+t/y+Y7227 intact-crc:6939AFB0EACEB2AF|rigid:deyco5EbnKrFocx6KKhe6TwOYe0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q86BI2 uniprotkb:P08646 intact:EBI-118360|ensemblmetazoa:FBpp0075536|ensemblmetazoa:FBpp0075537|ensemblmetazoa:FBpp0075538 intact:EBI-119517|uniprotkb:Q9V448|ensemblmetazoa:FBpp0081600 psi-mi:q86bi2_drome(display_long)|uniprotkb:Rgl(gene name)|psi-mi:Rgl(display_short)|uniprotkb:Rgl-RC(gene name synonym)|uniprotkb:DRgl(gene name synonym)|uniprotkb:Dmel\CG8865(gene name synonym)|uniprotkb:RalGDS(gene name synonym)|uniprotkb:RasGDS(gene name synonym)|uniprotkb:dRGL(gene name synonym)|uniprotkb:rgl(gene name synonym)|uniprotkb:Dmel_CG8865(orf name)|uniprotkb:CG8865(orf name) psi-mi:ras1_drome(display_long)|uniprotkb:Ras85D(gene name)|psi-mi:Ras85D(display_short)|uniprotkb:Ras1(gene name synonym)|uniprotkb:CG9375(orf name)|uniprotkb:Dmras85D(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874164 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0026376(gene)|ensemblmetazoa:FBtr0075794(transcript)|ensemblmetazoa:FBtr0075795(transcript)|ensemblmetazoa:FBtr0075796(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000159(Ras-association)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036964|refseq:NP_788503.1|refseq:NP_788504.1|refseq:NP_788505.1|flybase:FBgn0026376 refseq:NP_476699.1|flybase:FBgn0003205|ensemblmetazoa:FBgn0003205(gene)|ensemblmetazoa:FBtr0082122(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0001709"(cell fate determination)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0002168"(instar larval development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0019003"(GDP binding)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0000165"(MAPK cascade)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0040008"(regulation of growth)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0051607"(defense response to virus)|go:"GO:0060438"(trachea development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072002"(Malpighian tubule development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-DME-1250347|reactome:R-DME-1433557|reactome:R-DME-171007|reactome:R-DME-179812|reactome:R-DME-180336|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2871796|reactome:R-DME-375165|reactome:R-DME-3928662|reactome:R-DME-4086398|reactome:R-DME-432553|reactome:R-DME-5218921|reactome:R-DME-5621575|reactome:R-DME-5654688|reactome:R-DME-5654693|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5673000|reactome:R-DME-5673001|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-8951936|reactome:R-DME-9607240|reactome:R-DME-9634635|reactome:R-DME-9648002|dip:DIP-23541N pubmed:12529414(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:tdkQt55BAwB2gJNFoUBO70r9ZHw7227 rogid:+9A4GDDFmYKN5famfgTGA+t/y+Y7227 intact-crc:9595EE901158F9E2|rigid:L7RhbXuPIxnLGC9QWd+vKrGp73M false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P19018 uniprotkb:Q02427 intact:EBI-198424|uniprotkb:A4UZH1|uniprotkb:Q0E977|uniprotkb:Q9V734|ensemblmetazoa:FBpp0088562|ensemblmetazoa:FBpp0088946|ensemblmetazoa:FBpp0088947 intact:EBI-198500|uniprotkb:A4V2P0|uniprotkb:Q26271|uniprotkb:Q8T9K6|uniprotkb:Q9VGW8|uniprotkb:Q26280|ensemblmetazoa:FBpp0081754 psi-mi:tra2_drome(display_long)|uniprotkb:tra2(gene name)|psi-mi:tra2(display_short)|uniprotkb:tra-2(gene name synonym)|uniprotkb:CG10128(orf name) psi-mi:rbp1_drome(display_long)|uniprotkb:Rbp1(gene name)|psi-mi:Rbp1(display_short)|uniprotkb:CG17136(orf name)|uniprotkb:Rbp11(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874168 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476763.1|refseq:NP_476764.1|refseq:NP_476765.1|refseq:NP_476766.1|refseq:NP_599107.1|refseq:NP_995834.1|refseq:NP_995835.1|flybase:FBgn0003742|dip:DIP-17430N|ensemblmetazoa:FBgn0003742(gene)|ensemblmetazoa:FBtr0089617(transcript)|ensemblmetazoa:FBtr0089620(transcript)|ensemblmetazoa:FBtr0089621(transcript)|go:"GO:0000003"(reproduction)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0019101"(female somatic sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030237"(female sex determination)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-DME-6791226|reactome:R-DME-72163|reactome:R-DME-9013418|reactome:R-DME-9013422 refseq:NP_524307.1|refseq:NP_731510.1|flybase:FBgn0260944|ensemblmetazoa:FBgn0260944(gene)|ensemblmetazoa:FBtr0082277(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001178"(regulation of transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-DME-159236|reactome:R-DME-72163|reactome:R-DME-72165|reactome:R-DME-72187|reactome:R-DME-73856 pubmed:8990170(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:uL8i3jhKpNlSUIxgCb/9lb1L/1E7227 rogid:dOFdegSFcYR7a+Cqaoje1M8DuRk7227 intact-crc:58385BD6FD60BDF9|rigid:DPn6znPdH334nTk2nJtyfTg2GpU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q02427 uniprotkb:Q02427 intact:EBI-198500|uniprotkb:A4V2P0|uniprotkb:Q26271|uniprotkb:Q8T9K6|uniprotkb:Q9VGW8|uniprotkb:Q26280|ensemblmetazoa:FBpp0081754 intact:EBI-198500|uniprotkb:A4V2P0|uniprotkb:Q26271|uniprotkb:Q8T9K6|uniprotkb:Q9VGW8|uniprotkb:Q26280|ensemblmetazoa:FBpp0081754 psi-mi:rbp1_drome(display_long)|uniprotkb:Rbp1(gene name)|psi-mi:Rbp1(display_short)|uniprotkb:CG17136(orf name)|uniprotkb:Rbp11(gene name synonym) psi-mi:rbp1_drome(display_long)|uniprotkb:Rbp1(gene name)|psi-mi:Rbp1(display_short)|uniprotkb:CG17136(orf name)|uniprotkb:Rbp11(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874172 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524307.1|refseq:NP_731510.1|flybase:FBgn0260944|ensemblmetazoa:FBgn0260944(gene)|ensemblmetazoa:FBtr0082277(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001178"(regulation of transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-DME-159236|reactome:R-DME-72163|reactome:R-DME-72165|reactome:R-DME-72187|reactome:R-DME-73856 refseq:NP_524307.1|refseq:NP_731510.1|flybase:FBgn0260944|ensemblmetazoa:FBgn0260944(gene)|ensemblmetazoa:FBtr0082277(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001178"(regulation of transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-DME-159236|reactome:R-DME-72163|reactome:R-DME-72165|reactome:R-DME-72187|reactome:R-DME-73856 pubmed:8990170(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:dOFdegSFcYR7a+Cqaoje1M8DuRk7227 rogid:dOFdegSFcYR7a+Cqaoje1M8DuRk7227 intact-crc:455A9613F996C7DF|rigid:SWO6hOjokXReY2H63n4XcteS5Qg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9NDR2 uniprotkb:O61464 intact:EBI-870645 intact:EBI-870636 psi-mi:q9ndr2_drome(display_long)|uniprotkb:Drep4(gene name)|psi-mi:Drep4(display_short)|uniprotkb:Drep-4(gene name synonym)|uniprotkb:Rep4(gene name synonym)|uniprotkb:dCAD(gene name synonym)|uniprotkb:CG9414(orf name) psi-mi:o61464_drome(display_long)|uniprotkb:Drep1(gene name)|psi-mi:Drep1(display_short)|uniprotkb:Drep-1(gene name synonym)|uniprotkb:Rep1(gene name synonym)|uniprotkb:drep1(gene name synonym)|uniprotkb:CG8357(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874176 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028406|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006309"(apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729 flybase:FBgn0024732|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045476"(nurse cell apoptotic process)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|mint:O61464 pubmed:10777599(see-also)|pubmed:10781612(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6wYrQYh8bK3FmzNsEAvTVxb97VU7227 rogid:blDkwfR4tiQTHQ5/vHJGMLpbjk87227 intact-crc:DA92F2780C56A376|rigid:hiSFB9ZW8ccFVQRYiB7yMe9gimQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20227 uniprotkb:Q9V3K3 intact:EBI-169179|uniprotkb:Q9W2D8|ensemblmetazoa:FBpp0071596 intact:EBI-192924|ensemblmetazoa:FBpp0074756|ensemblmetazoa:FBpp0304236|ensemblmetazoa:FBpp0311247 psi-mi:tbp_drome(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:CG9874(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:ruvb2_drome(display_long)|uniprotkb:rept(gene name)|psi-mi:rept(display_short)|uniprotkb:CG9750(orf name)|uniprotkb:Dreptin(gene name synonym)|uniprotkb:Reptin(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874180 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523805.1|flybase:FBgn0003687|ensemblmetazoa:FBgn0003687(gene)|ensemblmetazoa:FBtr0071679(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519|dip:DIP-80N refseq:NP_524156.1|flybase:FBgn0040075|refseq:NP_001287113.1|refseq:NP_001262040.1|ensemblmetazoa:FBgn0040075(gene)|ensemblmetazoa:FBtr0074988(transcript)|ensemblmetazoa:FBtr0331852(transcript)|ensemblmetazoa:FBtr0344993(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043486"(histone exchange)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487 pubmed:11080158(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:eRlX8luNoF4M7SFmEnxKSbI6FJo7227 rogid:OTelAlg6zQwi3chtx0C/iDKL/607227 intact-crc:E0B03BFABC861967|rigid:7jqvUISdpp7m/cTcHcqU973An30 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q01083 uniprotkb:P20350 intact:EBI-91342|ensemblmetazoa:FBpp0080808|ensemblmetazoa:FBpp0080809|ensemblmetazoa:FBpp0080810|ensemblmetazoa:FBpp0080811|ensemblmetazoa:FBpp0100054|uniprotkb:Q8SXE0|uniprotkb:Q9VIT4 intact:EBI-172815|uniprotkb:Q9W0F2|ensemblmetazoa:FBpp0072578|ensemblmetazoa:FBpp0305409 psi-mi:spitz_drome(display_long)|uniprotkb:spi(gene name)|psi-mi:spi(display_short)|uniprotkb:CG10334(orf name) psi-mi:rhom_drome(display_long)|uniprotkb:rho(gene name)|psi-mi:rho(display_short)|uniprotkb:Ve(gene name synonym)|uniprotkb:CG1004(orf name)|uniprotkb:Protein veinlet(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874184 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005789"(endoplasmic reticulum membrane)|ensemblmetazoa:FBgn0005672(gene)|ensemblmetazoa:FBtr0081267(transcript)|ensemblmetazoa:FBtr0081268(transcript)|ensemblmetazoa:FBtr0081269(transcript)|ensemblmetazoa:FBtr0081270(transcript)|ensemblmetazoa:FBtr0100597(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001713"(ectodermal cell fate determination)|go:"GO:0003015"(heart process)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001027281.1|refseq:NP_476909.2|refseq:NP_599118.2|refseq:NP_599119.2|refseq:NP_599120.2|flybase:FBgn0005672|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007421"(stomatogastric nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:3C9A|rcsb pdb:3CA7|rcsb pdb:3LTF|rcsb pdb:3LTG|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|dip:DIP-18037N refseq:NP_523883.2|flybase:FBgn0004635|refseq:NP_001261255.1|go:"GO:0001752"(compound eye photoreceptor fate commitment)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007436"(larval salivary gland morphogenesis)|go:"GO:0007438"(oenocyte development)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|ensemblmetazoa:FBgn0004635(gene)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035311"(wing cell fate specification)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045177"(apical part of cell)|ensemblmetazoa:FBtr0072694(transcript)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0090317"(negative regulation of intracellular protein transport)|interpro:IPR017213(Peptidase S54, rhomboid, metazoan)|interpro:IPR022764|ensemblmetazoa:FBtr0333207(transcript)|interpro:IPR035952|go:"GO:0000281"(mitotic cytokinesis)|mint:P20350|go:"GO:0001742"(oenocyte differentiation) pubmed:11672524(see-also)|pubmed:11672525(see-also)|pubmed:12169630(see-also)|pubmed:9814706(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:RO8D5JspHbtNUFx11JHFCoUuv0A7227 rogid:1xLHqeP8taUKQZy9DJw9AkfcVr07227 intact-crc:BDC83CBA91514682|rigid:e3/wB9WRJzaVKjmx1Ik32OEQHSc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42519 uniprotkb:P20350 intact:EBI-184916|uniprotkb:Q9VPW0|ensemblmetazoa:FBpp0077658|ensemblmetazoa:FBpp0077659 intact:EBI-172815|uniprotkb:Q9W0F2|ensemblmetazoa:FBpp0072578|ensemblmetazoa:FBpp0305409 psi-mi:star_drome(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:CG4385(orf name) psi-mi:rhom_drome(display_long)|uniprotkb:rho(gene name)|psi-mi:rho(display_short)|uniprotkb:Ve(gene name synonym)|uniprotkb:CG1004(orf name)|uniprotkb:Protein veinlet(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874188 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523450.1|refseq:NP_722674.1|flybase:FBgn0003310|dip:DIP-22174N|ensemblmetazoa:FBgn0003310(gene)|ensemblmetazoa:FBtr0077993(transcript)|ensemblmetazoa:FBtr0077994(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007421"(stomatogastric nervous system development)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007601"(visual perception)|go:"GO:0016197"(endosomal transport)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|mint:P42519 refseq:NP_523883.2|flybase:FBgn0004635|refseq:NP_001261255.1|go:"GO:0001752"(compound eye photoreceptor fate commitment)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007436"(larval salivary gland morphogenesis)|go:"GO:0007438"(oenocyte development)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|ensemblmetazoa:FBgn0004635(gene)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035311"(wing cell fate specification)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045177"(apical part of cell)|ensemblmetazoa:FBtr0072694(transcript)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0090317"(negative regulation of intracellular protein transport)|interpro:IPR017213(Peptidase S54, rhomboid, metazoan)|interpro:IPR022764|ensemblmetazoa:FBtr0333207(transcript)|interpro:IPR035952|go:"GO:0000281"(mitotic cytokinesis)|mint:P20350|go:"GO:0001742"(oenocyte differentiation) pubmed:11799065(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8RiR9AUQmUsZN2w2weQ74nTjbls7227 rogid:1xLHqeP8taUKQZy9DJw9AkfcVr07227 intact-crc:3F5E0F720AFC5D54|rigid:xLngQRmRK7+lBom0ZqfoegTE42Q false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9U1K1 uniprotkb:P48148 intact:EBI-91672|intact:EBI-867570|intact:EBI-499570|uniprotkb:Q9VIN3|uniprotkb:Q9VIN4|uniprotkb:Q5U0Z8|uniprotkb:Q8INV3|uniprotkb:Q8INV4|uniprotkb:Q8INV5|uniprotkb:Q8SXP3|uniprotkb:Q8T8P8|uniprotkb:Q9U4F0|uniprotkb:Q9U4F1|ensemblmetazoa:FBpp0080884 intact:EBI-87246|uniprotkb:Q0E958|uniprotkb:Q9V3J0|ensemblmetazoa:FBpp0086353|ensemblmetazoa:FBpp0086354|ensemblmetazoa:FBpp0086355|ensemblmetazoa:FBpp0086356|ensemblmetazoa:FBpp0089129|ensemblmetazoa:FBpp0089130|uniprotkb:A4UZI6 psi-mi:spir_drome(display_long)|uniprotkb:spir(gene name)|psi-mi:spir(display_short)|uniprotkb:p150-Spir(gene name synonym)|uniprotkb:CG10076(orf name) psi-mi:rho1_drome(display_long)|uniprotkb:Rho1(gene name)|psi-mi:Rho1(display_short)|uniprotkb:CG8416(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874192 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001286100.1|refseq:NP_524854.2|refseq:NP_724254.1|refseq:NP_724255.1|refseq:NP_724256.2|flybase:FBgn0003475|ensemblmetazoa:FBgn0003475(gene)|ensemblmetazoa:FBtr0081352(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0046907"(intracellular transport)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0048477"(oogenesis)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0007316"(pole plasm RNA localization)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051639"(actin filament network formation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011019(KIND)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030029"(actin filament-based process)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0030036"(actin cytoskeleton organization)|interpro:IPR029901|rcsb pdb:3MMV|rcsb pdb:3MN5|rcsb pdb:3MN6|rcsb pdb:3MN7|rcsb pdb:3MN9|rcsb pdb:3UE5|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030717"(oocyte karyosome formation)|rcsb pdb:4EFH|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045010"(actin nucleation)|refseq:NP_001246102.1|dip:DIP-17301N ensemblmetazoa:FBgn0014020(gene)|ensemblmetazoa:FBtr0087211(transcript)|ensemblmetazoa:FBtr0087212(transcript)|ensemblmetazoa:FBtr0087213(transcript)|ensemblmetazoa:FBtr0087214(transcript)|ensemblmetazoa:FBtr0087216(transcript)|ensemblmetazoa:FBtr0087217(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007349"(cellularization)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007374"(posterior midgut invagination)|go:"GO:0007377"(germ-band extension)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0005737"(cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0070451"(cell hair)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0110020"(regulation of actomyosin structure organization)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-193634|reactome:R-DME-198203|reactome:R-DME-2173791|reactome:R-DME-350368|reactome:R-DME-350407|reactome:R-DME-350480|reactome:R-DME-392451|reactome:R-DME-3928662|reactome:R-DME-3928663|reactome:R-DME-4086400|interpro:IPR001806(Ras GTPase)|reactome:R-DME-416482|reactome:R-DME-416572|reactome:R-DME-4420097|reactome:R-DME-450728|reactome:R-DME-5625740|reactome:R-DME-5627117|reactome:R-DME-5663220|reactome:R-DME-5666185|reactome:R-DME-5689896|reactome:R-DME-6785631|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-8980692|reactome:R-DME-9013405|reactome:R-DME-9035034|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007601"(visual perception)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035006"(melanization defense response)|go:"GO:0035099"(hemocyte migration)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035298"(regulation of Malpighian tubule size)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0042060"(wound healing)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045179"(apical cortex)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046663"(dorsal closure, leading edge cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0035149"(lumen formation, open tracheal system)|refseq:NP_477098.1|refseq:NP_599135.1|refseq:NP_599136.1|refseq:NP_725524.1|refseq:NP_995849.1|refseq:NP_995850.1|flybase:FBgn0014020|dip:DIP-22676N pubmed:10556052(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:d5/uax72i+0dvjWvfORgiCSMjwQ7227 rogid:DbVx4weiFRCcGfqdsUQWqWQc0Q47227 intact-crc:2A8FDCD2451B0295|rigid:lkZCU9j1Avg1V8KD9NB87Q1tN1s false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q961D4 uniprotkb:P48148 intact:EBI-870271 intact:EBI-87246|uniprotkb:Q0E958|uniprotkb:Q9V3J0|ensemblmetazoa:FBpp0086353|ensemblmetazoa:FBpp0086354|ensemblmetazoa:FBpp0086355|ensemblmetazoa:FBpp0086356|ensemblmetazoa:FBpp0089129|ensemblmetazoa:FBpp0089130|uniprotkb:A4UZI6 psi-mi:q961d4_drome(display_long)|uniprotkb:Rok(gene name)|psi-mi:Rok(display_short)|uniprotkb:rok(gene name synonym)|uniprotkb:CG9774(orf name) psi-mi:rho1_drome(display_long)|uniprotkb:Rho1(gene name)|psi-mi:Rho1(display_short)|uniprotkb:CG8416(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874196 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0026181|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0003384"(apical constriction involved in gastrulation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007302"(nurse cell nucleus anchoring)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007391"(dorsal closure)|go:"GO:0008335"(female germline ring canal stabilization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008544"(epidermis development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032065"(maintenance of protein location in cell cortex)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035191"(nuclear axial expansion)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048599"(oocyte development)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0072518"(Rho-dependent protein serine/threonine kinase activity)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1903035"(negative regulation of response to wounding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015008(Rho Binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020684 ensemblmetazoa:FBgn0014020(gene)|ensemblmetazoa:FBtr0087211(transcript)|ensemblmetazoa:FBtr0087212(transcript)|ensemblmetazoa:FBtr0087213(transcript)|ensemblmetazoa:FBtr0087214(transcript)|ensemblmetazoa:FBtr0087216(transcript)|ensemblmetazoa:FBtr0087217(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007349"(cellularization)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007374"(posterior midgut invagination)|go:"GO:0007377"(germ-band extension)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0005737"(cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0070451"(cell hair)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0110020"(regulation of actomyosin structure organization)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-193634|reactome:R-DME-198203|reactome:R-DME-2173791|reactome:R-DME-350368|reactome:R-DME-350407|reactome:R-DME-350480|reactome:R-DME-392451|reactome:R-DME-3928662|reactome:R-DME-3928663|reactome:R-DME-4086400|interpro:IPR001806(Ras GTPase)|reactome:R-DME-416482|reactome:R-DME-416572|reactome:R-DME-4420097|reactome:R-DME-450728|reactome:R-DME-5625740|reactome:R-DME-5627117|reactome:R-DME-5663220|reactome:R-DME-5666185|reactome:R-DME-5689896|reactome:R-DME-6785631|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-8980692|reactome:R-DME-9013405|reactome:R-DME-9035034|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007601"(visual perception)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035006"(melanization defense response)|go:"GO:0035099"(hemocyte migration)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035298"(regulation of Malpighian tubule size)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0042060"(wound healing)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045179"(apical cortex)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046663"(dorsal closure, leading edge cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0035149"(lumen formation, open tracheal system)|refseq:NP_477098.1|refseq:NP_599135.1|refseq:NP_599136.1|refseq:NP_725524.1|refseq:NP_995849.1|refseq:NP_995850.1|flybase:FBgn0014020|dip:DIP-22676N pubmed:10570971(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:mN/LP4s8G6rMOrpeJxUEXLeQsjk7227 rogid:DbVx4weiFRCcGfqdsUQWqWQc0Q47227 intact-crc:8F3F8D1A40361EE1|rigid:htgLRvmszMozBw5AB6+LpNJyDCg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O44113 uniprotkb:P48148 intact:EBI-870654 intact:EBI-87246|uniprotkb:Q0E958|uniprotkb:Q9V3J0|ensemblmetazoa:FBpp0086353|ensemblmetazoa:FBpp0086354|ensemblmetazoa:FBpp0086355|ensemblmetazoa:FBpp0086356|ensemblmetazoa:FBpp0089129|ensemblmetazoa:FBpp0089130|uniprotkb:A4UZI6 psi-mi:o44113_drome(display_long)|uniprotkb:RhoGEF2(gene name)|psi-mi:RhoGEF2(display_short)|uniprotkb:rhoGEF2(gene name synonym)|uniprotkb:CG9635(orf name) psi-mi:rho1_drome(display_long)|uniprotkb:Rho1(gene name)|psi-mi:Rho1(display_short)|uniprotkb:CG8416(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874200 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0023172|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007277"(pole cell development)|go:"GO:0007349"(cellularization)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007374"(posterior midgut invagination)|go:"GO:0007375"(anterior midgut invagination)|go:"GO:0007377"(germ-band extension)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030478"(actin cap)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR041020|reactome:R-DME-350407 ensemblmetazoa:FBgn0014020(gene)|ensemblmetazoa:FBtr0087211(transcript)|ensemblmetazoa:FBtr0087212(transcript)|ensemblmetazoa:FBtr0087213(transcript)|ensemblmetazoa:FBtr0087214(transcript)|ensemblmetazoa:FBtr0087216(transcript)|ensemblmetazoa:FBtr0087217(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007349"(cellularization)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007374"(posterior midgut invagination)|go:"GO:0007377"(germ-band extension)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0005737"(cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0070451"(cell hair)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0110020"(regulation of actomyosin structure organization)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-193634|reactome:R-DME-198203|reactome:R-DME-2173791|reactome:R-DME-350368|reactome:R-DME-350407|reactome:R-DME-350480|reactome:R-DME-392451|reactome:R-DME-3928662|reactome:R-DME-3928663|reactome:R-DME-4086400|interpro:IPR001806(Ras GTPase)|reactome:R-DME-416482|reactome:R-DME-416572|reactome:R-DME-4420097|reactome:R-DME-450728|reactome:R-DME-5625740|reactome:R-DME-5627117|reactome:R-DME-5663220|reactome:R-DME-5666185|reactome:R-DME-5689896|reactome:R-DME-6785631|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-8980692|reactome:R-DME-9013405|reactome:R-DME-9035034|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007601"(visual perception)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035006"(melanization defense response)|go:"GO:0035099"(hemocyte migration)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035298"(regulation of Malpighian tubule size)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0042060"(wound healing)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045179"(apical cortex)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046663"(dorsal closure, leading edge cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0035149"(lumen formation, open tracheal system)|refseq:NP_477098.1|refseq:NP_599135.1|refseq:NP_599136.1|refseq:NP_725524.1|refseq:NP_995849.1|refseq:NP_995850.1|flybase:FBgn0014020|dip:DIP-22676N pubmed:9436986(see-also)|pubmed:9428514(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:HcTXt2jYqyRku8AFA6QCjzOX7PA7227 rogid:DbVx4weiFRCcGfqdsUQWqWQc0Q47227 intact-crc:66D44265D880F7D8|rigid:stvuxDOmBCzHE/x04UyJT8clVZU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q01083 uniprotkb:Q9VYW6 intact:EBI-91342|ensemblmetazoa:FBpp0080808|ensemblmetazoa:FBpp0080809|ensemblmetazoa:FBpp0080810|ensemblmetazoa:FBpp0080811|ensemblmetazoa:FBpp0100054|uniprotkb:Q8SXE0|uniprotkb:Q9VIT4 intact:EBI-108271|ensemblmetazoa:FBpp0073365|ensemblmetazoa:FBpp0073366 psi-mi:spitz_drome(display_long)|uniprotkb:spi(gene name)|psi-mi:spi(display_short)|uniprotkb:CG10334(orf name) psi-mi:q9vyw6_drome(display_long)|uniprotkb:rho-4(gene name)|psi-mi:rho-4(display_short)|uniprotkb:DmRho4(gene name synonym)|uniprotkb:Dmel\CG1697(gene name synonym)|uniprotkb:Rho-4(gene name synonym)|uniprotkb:Rho-related [10C6](gene name synonym)|uniprotkb:rho 4(gene name synonym)|uniprotkb:rho4(gene name synonym)|uniprotkb:Dmel_CG1697(orf name)|uniprotkb:CG1697(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874204 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005789"(endoplasmic reticulum membrane)|ensemblmetazoa:FBgn0005672(gene)|ensemblmetazoa:FBtr0081267(transcript)|ensemblmetazoa:FBtr0081268(transcript)|ensemblmetazoa:FBtr0081269(transcript)|ensemblmetazoa:FBtr0081270(transcript)|ensemblmetazoa:FBtr0100597(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001713"(ectodermal cell fate determination)|go:"GO:0003015"(heart process)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001027281.1|refseq:NP_476909.2|refseq:NP_599118.2|refseq:NP_599119.2|refseq:NP_599120.2|flybase:FBgn0005672|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007421"(stomatogastric nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:3C9A|rcsb pdb:3CA7|rcsb pdb:3LTF|rcsb pdb:3LTG|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|dip:DIP-18037N refseq:NP_727538.1|flybase:FBgn0030318|refseq:NP_525084.1|ensemblmetazoa:FBgn0030318(gene)|ensemblmetazoa:FBtr0073518(transcript)|ensemblmetazoa:FBtr0073519(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR017213(Peptidase S54, rhomboid, metazoan)|interpro:IPR018247|interpro:IPR022764|interpro:IPR035952 pubmed:12169630(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:RO8D5JspHbtNUFx11JHFCoUuv0A7227 rogid:rNG5P1Q+0DjT0WpIkQVw1obOprk7227 intact-crc:5A27EB3A53EB044B|rigid:nY2cU4G6x8A7GBe1vArELVJ8G5U false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24106 uniprotkb:P40417 intact:EBI-135509|uniprotkb:Q9VVP1|ensemblmetazoa:FBpp0074899|ensemblmetazoa:FBpp0305084 intact:EBI-867790|uniprotkb:A0A021WW06|uniprotkb:Q7PL59|uniprotkb:Q9W5M2|uniprotkb:A8Y4W1|uniprotkb:A8Y4W2|uniprotkb:Q9W5M3|ensemblmetazoa:FBpp0112423|ensemblmetazoa:FBpp0112425|ensemblmetazoa:FBpp0112426|ensemblmetazoa:FBpp0311493 psi-mi:hid_drome(display_long)|uniprotkb:hid(gene name)|psi-mi:hid(display_short)|uniprotkb:Protein head involution defective(gene name synonym)|uniprotkb:Protein wrinkled(gene name synonym)|uniprotkb:W(gene name synonym)|uniprotkb:CG5123(orf name) psi-mi:erka_drome(display_long)|uniprotkb:Extracellular-regulated kinase A(gene name synonym)|uniprotkb:Protein rolled(gene name synonym)|uniprotkb:rl(gene name)|psi-mi:rl(display_short)|uniprotkb:ERKa(gene name synonym)|uniprotkb:CG12559(orf name)|uniprotkb:MAPK(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874208 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524136.2|flybase:FBgn0003997|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008219"(cell death)|go:"GO:0008258"(head involution)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010114"(response to red light)|go:"GO:0012501"(programmed cell death)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005739"(mitochondrion)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1904747"(positive regulation of apoptotic process involved in development)|go:"GO:1990525"(BIR domain binding)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|rcsb pdb:1JD6|ensemblmetazoa:FBgn0003997(gene)|ensemblmetazoa:FBtr0075133(transcript)|ensemblmetazoa:FBtr0332862(transcript)|go:"GO:0002165"(instar larval or pupal development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001262010.1|dip:DIP-20052N refseq:NP_001015121.3|refseq:NP_001104348.2|refseq:NP_001287635.1|refseq:NP_001015122.1|refseq:NP_001015123.1|refseq:NP_001104349.1|flybase:FBgn0003256|dip:DIP-17266N|ensemblmetazoa:FBgn0003256(gene)|ensemblmetazoa:FBtr0113700(transcript)|ensemblmetazoa:FBtr0113702(transcript)|ensemblmetazoa:FBtr0113703(transcript)|ensemblmetazoa:FBtr0345337(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007362"(terminal region determination)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046534"(positive regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000826"(regulation of heart morphogenesis)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P40417|reactome:R-DME-110056|reactome:R-DME-112409|reactome:R-DME-112411|reactome:R-DME-1295596|reactome:R-DME-162658|reactome:R-DME-170968|reactome:R-DME-198753|reactome:R-DME-202670|reactome:R-DME-2029482|reactome:R-DME-2559580|reactome:R-DME-2559582|reactome:R-DME-2559585|reactome:R-DME-2871796|reactome:R-DME-3371453|reactome:R-DME-375165|reactome:R-DME-437239|reactome:R-DME-445144|reactome:R-DME-450341|reactome:R-DME-456926|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5654733|reactome:R-DME-5663213|reactome:R-DME-5673001|reactome:R-DME-5674135|reactome:R-DME-5674499|reactome:R-DME-5675221|reactome:R-DME-5687128|reactome:R-DME-6798695|reactome:R-DME-74749|reactome:R-DME-881907|reactome:R-DME-9634635|reactome:R-DME-9634638 pubmed:9814704(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:x/Jsu6gdz5rnLlOny3LOrreZP2c7227 rogid:m7w7KhuZSyx3t+dR2TKtvx/vRtA7227 intact-crc:A84EF3272DAE89A8|rigid:zkHMe8JZynAbOrATBjXuaReDNtw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P24014 uniprotkb:O44924 intact:EBI-498463|uniprotkb:Q24526|uniprotkb:Q8MLB9|uniprotkb:Q9V7F8|uniprotkb:Q9V7F9|uniprotkb:Q9XYV4|uniprotkb:A8DYF5|uniprotkb:A8DYF6|ensemblmetazoa:FBpp0303575|ensemblmetazoa:FBpp0303577 intact:EBI-74797 psi-mi:slit_drome(display_long)|uniprotkb:sli(gene name)|psi-mi:sli(display_short)|uniprotkb:CG43758(orf name) psi-mi:o44924_drome(display_long)|uniprotkb:robo1(gene name)|psi-mi:robo1(display_short)|uniprotkb:robo(gene name synonym)|uniprotkb:CG13521(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874212 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097333.1|refseq:NP_001097334.1|refseq:NP_476727.1|refseq:NP_476728.1|refseq:NP_476729.1|flybase:FBgn0264089|ensemblmetazoa:FBgn0264089(gene)|ensemblmetazoa:FBtr0330731(transcript)|ensemblmetazoa:FBtr0330733(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007502"(digestive tract mesoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008201"(heparin binding)|go:"GO:0008347"(glial cell migration)|go:"GO:0008406"(gonad development)|go:"GO:0009986"(cell surface)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050929"(induction of negative chemotaxis)|go:"GO:0071666"(Slit-Robo signaling complex)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR032675|rcsb pdb:1W8A|reactome:R-DME-376176|reactome:R-DME-428890 flybase:FBgn0005631|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0008038"(neuron recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008406"(gonad development)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0070983"(dendrite guidance)|go:"GO:0071666"(Slit-Robo signaling complex)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2VR9|rcsb pdb:2VRA pubmed:10102268(see-also)|pubmed:10102267(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:v/6IXr7nKdgRcNRzTGPvyzwpoKY7227 rogid:uLUQxfvRN9BQCyxNV6w22/4BtGw7227 intact-crc:25E0315C3990DD28|rigid:IjkcmIx5YqIoW8GdJQuY0hkha5c false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O44382 uniprotkb:Q9W5E1 intact:EBI-869364 intact:EBI-153139|uniprotkb:O77429|ensemblmetazoa:FBpp0070117|ensemblmetazoa:FBpp0310165 psi-mi:o44382_drome(display_long)|uniprotkb:slmb(gene name)|psi-mi:slmb(display_short)|uniprotkb:slimb(gene name synonym)|uniprotkb:CG3412(orf name) psi-mi:rbx1a_drome(display_long)|uniprotkb:Roc1a(gene name)|psi-mi:Roc1a(display_short)|uniprotkb:CG16982(orf name)|uniprotkb:Regulator of cullins 1a(gene name synonym)|uniprotkb:dRbx1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874216 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283468|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-432524 refseq:NP_001138143.2|ensemblmetazoa:FBgn0025638(gene)|ensemblmetazoa:FBtr0070122(transcript)|ensemblmetazoa:FBtr0343564(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|refseq:NP_569852.1|flybase:FBgn0025638|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016032"(viral process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045116"(protein neddylation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-DME-110314|reactome:R-DME-1234176|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-4641258|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-5696400|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-6782210|reactome:R-DME-68949|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|reactome:R-DME-983168|refseq:NP_001284754.1|dip:DIP-60717N pubmed:11500045(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:hKsZL6X4sxi/Zu4RDHlAV5IoZ2o7227 rogid:cdi4DGamYmT/5salxPwmZnusYVA7227 intact-crc:2F89EA660512EA9C|rigid:tdWMYQtNQpzmZTzizPe8syd2tdc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9I7U4 uniprotkb:Q8WS23 intact:EBI-867591|uniprotkb:O76275|uniprotkb:O76276|uniprotkb:O76277|uniprotkb:O76278|uniprotkb:O96767|uniprotkb:O96768|uniprotkb:Q7KA82|uniprotkb:Q7KAJ1|uniprotkb:Q7KPQ8|uniprotkb:Q7RTL4|uniprotkb:Q8T3N3|uniprotkb:Q9N2P7|uniprotkb:Q9N680|uniprotkb:Q9N9Y5|uniprotkb:Q9N9Y6|uniprotkb:Q9N9Y7|uniprotkb:Q9NFS3|uniprotkb:Q9NJP4|uniprotkb:Q9NL88|uniprotkb:Q9UB79|uniprotkb:Q9W055|uniprotkb:Q9XZT9|ensemblmetazoa:FBpp0072727|ensemblmetazoa:FBpp0304925 intact:EBI-870047 psi-mi:titin_drome(display_long)|uniprotkb:D-Titin(gene name synonym)|uniprotkb:Kettin(gene name synonym)|uniprotkb:sls(gene name)|psi-mi:sls(display_short)|uniprotkb:titin(gene name synonym)|uniprotkb:CG1915(orf name) psi-mi:q8ws23_drome(display_long)|uniprotkb:rols(gene name)|psi-mi:rols(display_short)|uniprotkb:rols6(gene name synonym)|uniprotkb:CG32096(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874220 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524676.2|flybase:FBgn0086906|ensemblmetazoa:FBgn0086906(gene)|ensemblmetazoa:FBtr0072848(transcript)|ensemblmetazoa:FBtr0332679(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003779"(actin binding)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007498"(mesoderm development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016203"(muscle attachment)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0031674"(I band)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0040011"(locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051301"(cell division)|interpro:IPR001452(Src homology-3)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010939(Protein of unknown function DUF1136)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|reactome:R-DME-5658623 flybase:FBgn0041096|go:"GO:0005737"(cytoplasm)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016740"(transferase activity)|go:"GO:0030018"(Z disc)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0061327"(anterior Malpighian tubule development)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002110(Ankyrin)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770 pubmed:11709189(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KudT+8stWca6bWBIOIHz4zh5mqY7227 rogid:liZ6VBX2yzld6LPOkXv5Ro19rKY7227 intact-crc:A5E12B917522F4CF|rigid:Oeh03tyLkCOdsrRBrZLqFtAEE3g false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24547 uniprotkb:Q07327 intact:EBI-135062|intact:EBI-1628359|uniprotkb:Q9TX14|uniprotkb:Q9VCD7|ensemblmetazoa:FBpp0083973|ensemblmetazoa:FBpp0352246 intact:EBI-181553|uniprotkb:Q24010|uniprotkb:Q9VZH8|ensemblmetazoa:FBpp0073119|ensemblmetazoa:FBpp0302752 psi-mi:stx1a_drome(display_long)|uniprotkb:Syx1A(gene name)|psi-mi:Syx1A(display_short)|uniprotkb:syx-1A(gene name synonym)|uniprotkb:CG31136(orf name)|uniprotkb:dSynt1(gene name synonym) psi-mi:rop_drome(display_long)|uniprotkb:Rop(gene name)|psi-mi:Rop(display_short)|uniprotkb:cs1(gene name synonym)|uniprotkb:CG15811(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874224 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524475.1|flybase:FBgn0013343|refseq:NP_001303545.1|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-449836|reactome:R-DME-888590|reactome:R-DME-9609523|ensemblmetazoa:FBgn0013343(gene)|go:"GO:0007482"(haltere development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|ensemblmetazoa:FBtr0084588(transcript)|ensemblmetazoa:FBtr0392904(transcript)|go:"GO:0000149"(SNARE binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|reactome:R-DME-181429|reactome:R-DME-181430|go:"GO:0007349"(cellularization)|dip:DIP-19389N refseq:NP_523916.2|flybase:FBgn0004574|refseq:NP_001261404.1|dip:DIP-18152N|ensemblmetazoa:FBgn0004574(gene)|ensemblmetazoa:FBtr0073263(transcript)|ensemblmetazoa:FBtr0310632(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0009416"(response to light stimulus)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032940"(secretion by cell)|go:"GO:0043195"(terminal bouton)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|reactome:R-DME-114516|reactome:R-DME-114608|reactome:R-DME-181429|reactome:R-DME-181430|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-449836|reactome:R-DME-888590 pubmed:9427747(see-also)|pubmed:10433270(see-also)|pubmed:7588884(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xlJYHz+B+bylWpjl2G3IUBud/5s7227 rogid:6etZFkF6v1ntgKDTDf/gPyu0QgE7227 intact-crc:178BC9811263D639|rigid:RNEgs0779uxgLu774RaE91puDj0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O17142 uniprotkb:Q94517 intact:EBI-870679 intact:EBI-302197|uniprotkb:O17429|uniprotkb:O77213|uniprotkb:Q9VZA1|ensemblmetazoa:FBpp0073173 psi-mi:o17142_drome(display_long)|uniprotkb:Sin3A(gene name)|psi-mi:Sin3A(display_short)|uniprotkb:CG8815(orf name) psi-mi:hdac1_drome(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:Rpd3(gene name synonym)|uniprotkb:CG7471(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874228 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0022764|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016580"(Sin3 complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035220"(wing disc development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774 ensemblmetazoa:FBgn0015805(gene)|ensemblmetazoa:FBtr0073317(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070983"(dendrite guidance)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0031523"(Myb complex)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q94517|reactome:R-DME-1538133|reactome:R-DME-201722|reactome:R-DME-209394|reactome:R-DME-3214815|reactome:R-DME-3769402|reactome:R-DME-6804758|reactome:R-DME-8943724|reactome:R-DME-983231|refseq:NP_647918.2|flybase:FBgn0015805|dip:DIP-29512N pubmed:11080159(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:EYjzMyBlpsi6fRLtizbsQZgp96o7227 rogid:HYHCai8wP8lueOr33vYY32w2pHU7227 intact-crc:27478A34D96C24BA|rigid:TYL8g+LefBT7SreFAzXzjjmsoWY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20227 uniprotkb:P04052 intact:EBI-169179|uniprotkb:Q9W2D8|ensemblmetazoa:FBpp0071596 intact:EBI-173525|uniprotkb:Q9VYX6|ensemblmetazoa:FBpp0073387 psi-mi:tbp_drome(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:CG9874(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:rpb1_drome(display_long)|uniprotkb:RpII215(gene name)|psi-mi:RpII215(display_short)|uniprotkb:CG1554(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874232 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523805.1|flybase:FBgn0003687|ensemblmetazoa:FBgn0003687(gene)|ensemblmetazoa:FBtr0071679(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519|dip:DIP-80N refseq:NP_511124.1|flybase:FBgn0003277|dip:DIP-22282N|ensemblmetazoa:FBgn0003277(gene)|ensemblmetazoa:FBtr0073542(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|reactome:R-DME-112382|reactome:R-DME-113418|reactome:R-DME-674695|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-6782210|reactome:R-DME-6796648|reactome:R-DME-6803529|reactome:R-DME-6807505|reactome:R-DME-72086|reactome:R-DME-72163|reactome:R-DME-72165|reactome:R-DME-72203|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-75955|reactome:R-DME-76042|reactome:R-DME-77075|reactome:R-DME-9018519 pubmed:9407112(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:eRlX8luNoF4M7SFmEnxKSbI6FJo7227 rogid:15kW36zkVzQkXGBb5/mQk4h4lSM7227 intact-crc:8C9E33073D6B75EF|rigid:Sv4wR7nY3K/6O1p+Z6+C+ZYOZMA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24306 uniprotkb:Q24475 intact:EBI-456419|uniprotkb:A4V1Z9|uniprotkb:Q0E8E4|uniprotkb:Q8MRM5|uniprotkb:Q9VUX5|uniprotkb:A9UN33|ensemblmetazoa:FBpp0075254|ensemblmetazoa:FBpp0075255|ensemblmetazoa:FBpp0075256|ensemblmetazoa:FBpp0305793|ensemblmetazoa:FBpp0305794|ensemblmetazoa:FBpp0305795 intact:EBI-106786|uniprotkb:A0JQ43|uniprotkb:Q4V3S2|uniprotkb:Q9VVP7|ensemblmetazoa:FBpp0074886 psi-mi:diap1_drome(display_long)|uniprotkb:Diap1(gene name)|psi-mi:Diap1(display_short)|uniprotkb:Apoptosis 1 inhibitor(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase th(gene name synonym)|uniprotkb:Iap1(gene name synonym)|uniprotkb:Inhibitor of apoptosis 1(gene name synonym)|uniprotkb:Protein thread(gene name synonym)|uniprotkb:th(gene name synonym)|uniprotkb:CG12284(orf name)|uniprotkb:RING-type E3 ubiquitin transferase Diap1(gene name synonym) psi-mi:rpr_drome(display_long)|uniprotkb:Protein reaper(gene name synonym)|uniprotkb:rpr(gene name)|psi-mi:rpr(display_short)|uniprotkb:CG4319(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874236 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524101.2|refseq:NP_730097.1|refseq:NP_730098.1|flybase:FBgn0260635|refseq:NP_001261916.1|refseq:NP_001261917.1|refseq:NP_001261918.1|go:"GO:0006915"(apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0022416"(chaeta development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0045116"(protein neddylation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|ensemblmetazoa:FBgn0260635(gene)|ensemblmetazoa:FBtr0075499(transcript)|ensemblmetazoa:FBtr0075500(transcript)|ensemblmetazoa:FBtr0075501(transcript)|ensemblmetazoa:FBtr0333617(transcript)|ensemblmetazoa:FBtr0333618(transcript)|ensemblmetazoa:FBtr0333619(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|mint:Q24306|rcsb pdb:1JD4|rcsb pdb:1JD5|rcsb pdb:1JD6|rcsb pdb:1Q4Q|rcsb pdb:1SDZ|rcsb pdb:1SE0|rcsb pdb:3SIP|rcsb pdb:3SIQ|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-3769402|reactome:R-DME-390150|reactome:R-DME-5675482|reactome:R-DME-8948747|reactome:R-DME-8948751 refseq:NP_524138.1|flybase:FBgn0011706|dip:DIP-21897N|ensemblmetazoa:FBgn0011706(gene)|ensemblmetazoa:FBtr0075120(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008219"(cell death)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0012501"(programmed cell death)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0035193"(larval central nervous system remodeling)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis) pubmed:10655220(see-also)|pubmed:12446669(see-also)|pubmed:9294184(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:loBQ//cKQ1NYhq3gnIKwRBn5vZg7227 rogid:dfUqX1oqC/PI0TTvY+EBfGyh5k47227 intact-crc:53FDAE4B5331D063|rigid:9RV2pCSm/uKRNhsMb9nwplwItMs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9V3W7 uniprotkb:Q24491 intact:EBI-93356|intact:EBI-1628034|ensemblmetazoa:FBpp0082724|ensemblmetazoa:FBpp0293269 intact:EBI-190223|uniprotkb:Q24424|uniprotkb:Q9VL15|ensemblmetazoa:FBpp0079668 psi-mi:q9v3w7_drome(display_long)|uniprotkb:SF2(gene name)|psi-mi:SF2(display_short)|uniprotkb:p28/SF2(gene name synonym)|uniprotkb:154911_at(gene name synonym)|uniprotkb:ASF(gene name synonym)|uniprotkb:Dmel\CG6987(gene name synonym)|uniprotkb:SRp30(gene name synonym)|uniprotkb:dASF(gene name synonym)|uniprotkb:dSF2(gene name synonym)|uniprotkb:dSRp30(gene name synonym)|uniprotkb:dmSF2(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:Dmel_CG6987(orf name)|uniprotkb:CG6987(orf name)|uniprotkb:cg6987(gene name synonym)|uniprotkb:SRSF1(gene name synonym) psi-mi:rx21_drome(display_long)|uniprotkb:Rsf1(gene name)|psi-mi:Rsf1(display_short)|uniprotkb:ROX21(gene name synonym)|uniprotkb:CG5655(orf name)|uniprotkb:RNA-binding protein Rox21(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874240 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283477|refseq:NP_652611.1|refseq:NP_001247139.1|ensemblmetazoa:FBgn0283477(gene)|ensemblmetazoa:FBtr0083272(transcript)|ensemblmetazoa:FBtr0304727(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001178"(regulation of transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|reactome:R-DME-159236|reactome:R-DME-72163|reactome:R-DME-72165|reactome:R-DME-72187|reactome:R-DME-73856 refseq:NP_477001.2|flybase:FBgn0011305|refseq:NP_001260318.1|ensemblmetazoa:FBgn0011305(gene)|ensemblmetazoa:FBtr0080079(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001178"(regulation of transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 pubmed:10090730(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:IxkPdVi2EeVb5mVcIaeGY7ptbTw7227 rogid:1ig36rqek1X3sLlFIU3u/CJcvFA7227 intact-crc:F279B0B85C7AA56A|rigid:2oDXMpC4b1PJIanoKhvdvxPV9e0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q01083 uniprotkb:Q9W0F8 intact:EBI-91342|ensemblmetazoa:FBpp0080808|ensemblmetazoa:FBpp0080809|ensemblmetazoa:FBpp0080810|ensemblmetazoa:FBpp0080811|ensemblmetazoa:FBpp0100054|uniprotkb:Q8SXE0|uniprotkb:Q9VIT4 intact:EBI-159101|ensemblmetazoa:FBpp0072574|uniprotkb:Q9BML3 psi-mi:spitz_drome(display_long)|uniprotkb:spi(gene name)|psi-mi:spi(display_short)|uniprotkb:CG10334(orf name) psi-mi:q9w0f8_drome(display_long)|uniprotkb:ru(gene name)|psi-mi:ru(display_short)|uniprotkb:Dmel\CG1214(gene name synonym)|uniprotkb:Rho-3(gene name synonym)|uniprotkb:Rho-related [62A1](gene name synonym)|uniprotkb:Rho3(gene name synonym)|uniprotkb:rho-3(gene name synonym)|uniprotkb:rho3(gene name synonym)|uniprotkb:Dmel_CG1214(orf name)|uniprotkb:CG1214(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874244 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005789"(endoplasmic reticulum membrane)|ensemblmetazoa:FBgn0005672(gene)|ensemblmetazoa:FBtr0081267(transcript)|ensemblmetazoa:FBtr0081268(transcript)|ensemblmetazoa:FBtr0081269(transcript)|ensemblmetazoa:FBtr0081270(transcript)|ensemblmetazoa:FBtr0100597(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001713"(ectodermal cell fate determination)|go:"GO:0003015"(heart process)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001027281.1|refseq:NP_476909.2|refseq:NP_599118.2|refseq:NP_599119.2|refseq:NP_599120.2|flybase:FBgn0005672|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007421"(stomatogastric nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:3C9A|rcsb pdb:3CA7|rcsb pdb:3LTF|rcsb pdb:3LTG|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|dip:DIP-18037N ensemblmetazoa:FBgn0003295(gene)|ensemblmetazoa:FBtr0072681(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001752"(compound eye photoreceptor fate commitment)|go:"GO:0003015"(heart process)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|go:"GO:0042676"(compound eye cone cell fate commitment)|go:"GO:0045177"(apical part of cell)|go:"GO:0050714"(positive regulation of protein secretion)|interpro:IPR017213(Peptidase S54, rhomboid, metazoan)|interpro:IPR022764|interpro:IPR035952|refseq:NP_524790.1|flybase:FBgn0003295 pubmed:12169630(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:RO8D5JspHbtNUFx11JHFCoUuv0A7227 rogid:Fl5art/krhlG8AxqX+r9kU7Iy1o7227 intact-crc:C066DFA7C3EBF73B|rigid:CkhuZYHOroOd7DSK8hhiLWXdubI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42519 uniprotkb:Q86P37 intact:EBI-184916|uniprotkb:Q9VPW0|ensemblmetazoa:FBpp0077658|ensemblmetazoa:FBpp0077659 intact:EBI-870063|ensemblmetazoa:FBpp0072596 psi-mi:star_drome(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:CG4385(orf name) psi-mi:q86p37_drome(display_long)|uniprotkb:stet(gene name)|psi-mi:stet(display_short)|uniprotkb:rho-2(gene name synonym)|uniprotkb:CG33166(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874248 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523450.1|refseq:NP_722674.1|flybase:FBgn0003310|dip:DIP-22174N|ensemblmetazoa:FBgn0003310(gene)|ensemblmetazoa:FBtr0077993(transcript)|ensemblmetazoa:FBtr0077994(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007421"(stomatogastric nervous system development)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007601"(visual perception)|go:"GO:0016197"(endosomal transport)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|mint:P42519 flybase:FBgn0020248|ensemblmetazoa:FBgn0020248(gene)|ensemblmetazoa:FBtr0072712(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR017213(Peptidase S54, rhomboid, metazoan)|interpro:IPR022764|interpro:IPR035952 pubmed:11023685(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:8RiR9AUQmUsZN2w2weQ74nTjbls7227 rogid:/V81SvMh6SpQatDYm99oUPvZ9887227 intact-crc:02CFF6BE5A3B66FF|rigid:Cy2ZOOasGQExhf/X11oTlb+DXKg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q01083 uniprotkb:P42519 intact:EBI-91342|ensemblmetazoa:FBpp0080808|ensemblmetazoa:FBpp0080809|ensemblmetazoa:FBpp0080810|ensemblmetazoa:FBpp0080811|ensemblmetazoa:FBpp0100054|uniprotkb:Q8SXE0|uniprotkb:Q9VIT4 intact:EBI-184916|uniprotkb:Q9VPW0|ensemblmetazoa:FBpp0077658|ensemblmetazoa:FBpp0077659 psi-mi:spitz_drome(display_long)|uniprotkb:spi(gene name)|psi-mi:spi(display_short)|uniprotkb:CG10334(orf name) psi-mi:star_drome(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:CG4385(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874252 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005789"(endoplasmic reticulum membrane)|ensemblmetazoa:FBgn0005672(gene)|ensemblmetazoa:FBtr0081267(transcript)|ensemblmetazoa:FBtr0081268(transcript)|ensemblmetazoa:FBtr0081269(transcript)|ensemblmetazoa:FBtr0081270(transcript)|ensemblmetazoa:FBtr0100597(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001713"(ectodermal cell fate determination)|go:"GO:0003015"(heart process)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001027281.1|refseq:NP_476909.2|refseq:NP_599118.2|refseq:NP_599119.2|refseq:NP_599120.2|flybase:FBgn0005672|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007421"(stomatogastric nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:3C9A|rcsb pdb:3CA7|rcsb pdb:3LTF|rcsb pdb:3LTG|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|dip:DIP-18037N refseq:NP_523450.1|refseq:NP_722674.1|flybase:FBgn0003310|dip:DIP-22174N|ensemblmetazoa:FBgn0003310(gene)|ensemblmetazoa:FBtr0077993(transcript)|ensemblmetazoa:FBtr0077994(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007421"(stomatogastric nervous system development)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007601"(visual perception)|go:"GO:0016197"(endosomal transport)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0038004"(epidermal growth factor receptor ligand maturation)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|mint:P42519 pubmed:11672524(see-also)|pubmed:11799065(see-also)|pubmed:11520660(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:RO8D5JspHbtNUFx11JHFCoUuv0A7227 rogid:8RiR9AUQmUsZN2w2weQ74nTjbls7227 intact-crc:12ABC1886084A720|rigid:0qLEIvkTLcfstUujA3iNnyB50Ak false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8T9I6 uniprotkb:P91656 intact:EBI-870694|ensemblmetazoa:FBpp0080003 intact:EBI-466629 psi-mi:q8t9i6_drome(display_long)|uniprotkb:Tor(gene name)|psi-mi:Tor(display_short)|uniprotkb:CG5092(orf name) psi-mi:p91656_drome(display_long)|uniprotkb:CG10539(orf name)|uniprotkb:S6k(gene name)|psi-mi:S6k(display_short) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874256 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0021796|ensemblmetazoa:FBgn0021796(gene)|ensemblmetazoa:FBtr0080422(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR018936|interpro:IPR026683|interpro:IPR036940|reactome:R-DME-110523 flybase:FBgn0283472|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0031929"(TOR signaling)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:2000331"(regulation of terminal button organization)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016238(Ribosomal protein S6 kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|reactome:R-DME-110523|go:"GO:0008340"(determination of adult lifespan) pubmed:11069888(see-also)|pubmed:11069885(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:a4AXe+fXlN94fxIdEMt/4mDIEy47227 rogid:vY523/d3IX+Jh8UXjlIJaVVGFuw7227 intact-crc:29298C97F03BEFFA|rigid:fhhXMzzErjdBWd1VB8dPtsp5wsU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24096 uniprotkb:Q9VCR6 intact:EBI-466930|ensemblmetazoa:FBpp0085082 intact:EBI-145004|uniprotkb:Q8MQH6|uniprotkb:Q8T9A6|uniprotkb:Q9VCR5|ensemblmetazoa:FBpp0083749 psi-mi:q24096_drome(display_long)|uniprotkb:CG12072(orf name)|uniprotkb:wts(gene name)|psi-mi:wts(display_short) psi-mi:sav_drome(display_long)|uniprotkb:sav(gene name)|psi-mi:sav(display_short)|uniprotkb:SHRP(gene name synonym)|uniprotkb:CG33193(orf name)|uniprotkb:Shar-pei(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874260 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0011739(gene)|ensemblmetazoa:FBtr0085720(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028742|flybase:FBgn0011739 refseq:NP_788721.1|flybase:FBgn0053193|dip:DIP-18696N|ensemblmetazoa:FBgn0053193(gene)|ensemblmetazoa:FBtr0084356(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007444"(imaginal disc development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0035329"(hippo signaling)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072002"(Malpighian tubule development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0106037"(apicomedial cortex)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR011524(SARAH)|interpro:IPR030030|interpro:IPR036020|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150 pubmed:12202036(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:eq0d80VgWQInZpFpfCeR4+9GxOU7227 rogid:/omCdWbZCQT01Iwj5eU7isz1Kr47227 intact-crc:CD2564B9B25C7FDD|rigid:IqfJ+UqPePbvqBtLyxdqbDRQCWY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P54631 uniprotkb:Q7JQ36 intact:EBI-118117|uniprotkb:Q8INV8|ensemblmetazoa:FBpp0080802|ensemblmetazoa:FBpp0310402 intact:EBI-121415|ensemblmetazoa:FBpp0087908 psi-mi:scw_drome(display_long)|uniprotkb:scw(gene name)|psi-mi:scw(display_short)|uniprotkb:CG31695(orf name) psi-mi:q7jq36_drome(display_long)|uniprotkb:sax(gene name)|psi-mi:sax(display_short)|uniprotkb:Sax(gene name synonym)|uniprotkb:CG1891(orf name)|uniprotkb:Dmel_CG1891(orf name)|uniprotkb:Bkr43E(gene name synonym)|uniprotkb:Brk43E(gene name synonym)|uniprotkb:Dmel\CG1891(gene name synonym)|uniprotkb:SAX(gene name synonym)|uniprotkb:STK-B(gene name synonym)|uniprotkb:Sa(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874264 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524863.3|flybase:FBgn0005590|ensemblmetazoa:FBgn0005590(gene)|ensemblmetazoa:FBtr0081261(transcript)|ensemblmetazoa:FBtr0343860(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0007378"(amnioserosa formation)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007502"(digestive tract mesoderm development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008406"(gonad development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR001111("Transforming growth factor beta (TGFb), N-terminal")|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR017948|interpro:IPR029034|reactome:R-DME-114608|reactome:R-DME-2129379|reactome:R-DME-2173789|reactome:R-DME-2173791|reactome:R-DME-3000170|reactome:R-DME-381426|reactome:R-DME-8941855|reactome:R-DME-8941858|reactome:R-DME-8951936|reactome:R-DME-8957275|go:"GO:0048018"(receptor ligand activity)|refseq:NP_001286088.1|dip:DIP-59820N refseq:NP_523652.2|flybase:FBgn0003317|ensemblmetazoa:FBgn0003317(gene)|ensemblmetazoa:FBtr0088832(transcript)|go:"GO:0004675"(transmembrane receptor protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008358"(maternal determination of anterior/posterior axis, embryo)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR000333(Activin type II receptor)|interpro:IPR000472(TGF-beta receptor/activin receptor, type I/II)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003605(TGF beta receptor, GS motif)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) pubmed:9827801(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:VifIwMWiUB+/kdW9WIzvSzggc9w7227 rogid:5cRHvkW8tEh2vkAn6uLRSdu8/Y87227 intact-crc:E35690F1252544D5|rigid:J8zDVeBezRWcCR9WV1KzNdhp1cM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20659 uniprotkb:O96610 intact:EBI-591327|ensemblmetazoa:FBpp0082406|ensemblmetazoa:FBpp0082409|uniprotkb:Q27255|uniprotkb:Q27327|uniprotkb:Q8INF9|uniprotkb:Q960R2|uniprotkb:Q9VFL1|uniprotkb:A4V2V9|uniprotkb:A4V2W0|intact:EBI-3404288|intact:EBI-3417031|intact:EBI-9922180|intact:EBI-9933604 intact:EBI-870709 psi-mi:trx_drome(display_long)|uniprotkb:KMT2A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2A(gene name synonym)|uniprotkb:trx(gene name)|psi-mi:trx(display_short)|uniprotkb:CG8651(orf name)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:o96610_drome(display_long)|uniprotkb:Sbf(gene name)|psi-mi:Sbf(display_short)|uniprotkb:sbf(gene name synonym)|uniprotkb:CG6939(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874268 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0003862(gene)|ensemblmetazoa:FBtr0082947(transcript)|ensemblmetazoa:FBtr0082950(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|reactome:R-DME-8936459|reactome:R-DME-8939236|refseq:NP_001014621.1|refseq:NP_476769.1|refseq:NP_476770.1|refseq:NP_599108.1|refseq:NP_599109.1|flybase:FBgn0003862 flybase:FBgn0025802|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005938"(cell cortex)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032483"(regulation of Rab protein signal transduction)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0055037"(recycling endosome)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR001194(DENN)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR004182(GRAM)|interpro:IPR005112(dDENN)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022096|interpro:IPR029021|interpro:IPR030564|interpro:IPR037516|interpro:IPR043153 pubmed:11701926(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:LDT4/pLaHAuL/kuZMReRH9ZDrNk7227 rogid:fPIQEwqJszyoXNAMEtyq/9Vvr2M7227 intact-crc:FD05F1EB1396F783|rigid:cwqnAcHT9FFg1Y0IJhIsJmYAyFo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10084 uniprotkb:P10084 intact:EBI-174136|intact:EBI-1639078|uniprotkb:O76890|uniprotkb:Q4V705|ensemblmetazoa:FBpp0070072 intact:EBI-174136|intact:EBI-1639078|uniprotkb:O76890|uniprotkb:Q4V705|ensemblmetazoa:FBpp0070072 psi-mi:ast4_drome(display_long)|uniprotkb:sc(gene name)|psi-mi:sc(display_short)|uniprotkb:T4(gene name synonym)|uniprotkb:Protein scute(gene name synonym)|uniprotkb:sis-b(gene name synonym)|uniprotkb:CG3827(orf name) psi-mi:ast4_drome(display_long)|uniprotkb:sc(gene name)|psi-mi:sc(display_short)|uniprotkb:T4(gene name synonym)|uniprotkb:Protein scute(gene name synonym)|uniprotkb:sis-b(gene name synonym)|uniprotkb:CG3827(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874272 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476803.1|flybase:FBgn0004170|dip:DIP-325N|ensemblmetazoa:FBgn0004170(gene)|ensemblmetazoa:FBtr0070073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638 refseq:NP_476803.1|flybase:FBgn0004170|dip:DIP-325N|ensemblmetazoa:FBgn0004170(gene)|ensemblmetazoa:FBtr0070073(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007540"("sex determination, establishment of X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0022416"(chaeta development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015660(Achaete-scute transcription factor related)|interpro:IPR036638 pubmed:8757393(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:WTTmp3SuZ10YiZMKYALr68UiRO07227 rogid:WTTmp3SuZ10YiZMKYALr68UiRO07227 intact-crc:84C4702CC2C923A1|rigid:Oqj6iqXp/dmQZJ37DdPYAqjzBZA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9Y103 uniprotkb:Q7KTD2 intact:EBI-174432|intact:EBI-501125|uniprotkb:Q9NHN7|ensemblmetazoa:FBpp0078765|ensemblmetazoa:FBpp0311644 intact:EBI-870730|ensemblmetazoa:FBpp0088837 psi-mi:tfp11_drome(display_long)|uniprotkb:sip1(gene name)|psi-mi:sip1(display_short)|uniprotkb:stip-1(gene name synonym)|uniprotkb:CG7238(orf name)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym) psi-mi:q7ktd2_drome(display_long)|uniprotkb:CG15494(gene name synonym)|uniprotkb:CG5542(gene name synonym)|uniprotkb:SC35(gene name)|psi-mi:SC35(display_short)|uniprotkb:Dmel\CG5442(gene name synonym)|uniprotkb:SC-35(gene name synonym)|uniprotkb:Sc35(gene name synonym)|uniprotkb:"anon-EST:Posey284"(gene name synonym)|uniprotkb:dSC35(gene name synonym)|uniprotkb:sc35(gene name synonym)|uniprotkb:Dmel_CG5442(orf name)|uniprotkb:cg5442(gene name synonym)|uniprotkb:CG5442(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874276 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524725.2|flybase:FBgn0024191|refseq:NP_001285636.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|ensemblmetazoa:FBgn0024191(gene)|ensemblmetazoa:FBtr0079134(transcript)|ensemblmetazoa:FBtr0345545(transcript)|go:"GO:0000390"(spliceosomal complex disassembly) flybase:FBgn0265298|refseq:NP_995689.1|ensemblmetazoa:FBgn0265298(gene)|ensemblmetazoa:FBtr0089898(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001178"(regulation of transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031440"(regulation of mRNA 3'-end processing) pubmed:9447963(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:PJxaiEhZk9uaagQ6GWSK7ryjojU7227 rogid:WcwKyUV5oGtut03YDlajSX7Re4M7227 intact-crc:F316112BA3DC7D18|rigid:Ep4jLhzlcCPJw/+ApxOonwAoxSE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q26366 uniprotkb:P30052 intact:EBI-162687|uniprotkb:Q9V6H9|ensemblmetazoa:FBpp0086898 intact:EBI-151228|uniprotkb:Q9VXN7|ensemblmetazoa:FBpp0073914|ensemblmetazoa:FBpp0111737|ensemblmetazoa:FBpp0111738|ensemblmetazoa:FBpp0111739|ensemblmetazoa:FBpp0300451|ensemblmetazoa:FBpp0301995|ensemblmetazoa:FBpp0301996 psi-mi:vg_drome(display_long)|uniprotkb:vg(gene name)|psi-mi:vg(display_short)|uniprotkb:CG3830(orf name) psi-mi:scal_drome(display_long)|uniprotkb:sd(gene name)|psi-mi:sd(display_short)|uniprotkb:CG8544(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874284 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523723.1|flybase:FBgn0003975|ensemblmetazoa:FBgn0003975(gene)|ensemblmetazoa:FBtr0087785(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007451"(dorsal/ventral lineage restriction, imaginal disc)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007473"(wing disc proximal/distal pattern formation)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016204"(determination of muscle attachment site)|go:"GO:0035220"(wing disc development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|interpro:IPR006627(Protein of unknown function TDU)|interpro:IPR011520(Vestigial/tondu)|rcsb pdb:6Y20 refseq:NP_001245697.1|refseq:NP_001096990.1|refseq:NP_001096991.1|refseq:NP_001096992.1|refseq:NP_511169.1|flybase:FBgn0003345|refseq:NP_001259582.1|refseq:NP_001259583.1|dip:DIP-21510N|ensemblmetazoa:FBgn0003345(gene)|ensemblmetazoa:FBtr0074099(transcript)|ensemblmetazoa:FBtr0112825(transcript)|ensemblmetazoa:FBtr0112826(transcript)|ensemblmetazoa:FBtr0112827(transcript)|ensemblmetazoa:FBtr0308129(transcript)|ensemblmetazoa:FBtr0310312(transcript)|ensemblmetazoa:FBtr0310313(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007423"(sensory organ development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007525"(somatic muscle development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035220"(wing disc development)|go:"GO:0035329"(hippo signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000826"(regulation of heart morphogenesis)|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|interpro:IPR038096|interpro:IPR041086|rcsb pdb:6Y20|reactome:R-DME-2032785|reactome:R-DME-390193|reactome:R-DME-8951671 pubmed:11731237(see-also)|pubmed:9869643(see-also)|pubmed:9799424(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:uqFsfdTbzrZXahVD8igBvVK6t2o7227 rogid:SO+AbZes9cF5kqYvD2xcz3ZC/wk7227 intact-crc:A7385D938FA0A494|rigid:Ol6hKIoS7CN96OZR/mbgRXpGqjU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42207 uniprotkb:Q7KJV6 intact:EBI-120528|uniprotkb:Q9VRH5|uniprotkb:Q8IQ47|ensemblmetazoa:FBpp0076897 intact:EBI-867875 psi-mi:sept1_drome(display_long)|uniprotkb:DIFF6 protein homolog(gene name synonym)|uniprotkb:Protein innocent bystander(gene name synonym)|uniprotkb:CG1403(orf name)|uniprotkb:Sep1(gene name)|psi-mi:Sep1(display_short)|uniprotkb:Diff6(gene name synonym)|uniprotkb:iby(gene name synonym) psi-mi:q7kjv6_drome(display_long)|uniprotkb:Uba2(gene name)|psi-mi:Uba2(display_short)|uniprotkb:CG7528(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874288 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0011710(gene)|ensemblmetazoa:FBtr0077198(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0007349"(cellularization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|refseq:NP_523430.1|flybase:FBgn0011710|dip:DIP-18454N flybase:FBgn0029113|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033134"(ubiquitin activating enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR019572|interpro:IPR023318|interpro:IPR028077|interpro:IPR030661|interpro:IPR033127|interpro:IPR035985|interpro:IPR042449 pubmed:11884525(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:owbyZvFu8+uF3t60BTm9IqquTL47227 rogid:6hSWdsAvG5y2/bW1XcSHzO+1b0A7227 intact-crc:366BC2F8A542E5DA|rigid:K9nrAdOBrl6PUjA5Rk+tKWKn/PM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KTL4 uniprotkb:P42207 intact:EBI-870738|ensemblmetazoa:FBpp0078987 intact:EBI-120528|uniprotkb:Q9VRH5|uniprotkb:Q8IQ47|ensemblmetazoa:FBpp0076897 psi-mi:q7ktl4_drome(display_long)|uniprotkb:sip2(gene name)|psi-mi:sip2(display_short)|uniprotkb:Dmel\CG9188(gene name synonym)|uniprotkb:FIP(gene name synonym)|uniprotkb:fip(gene name synonym)|uniprotkb:CG9188(orf name)|uniprotkb:Dmel_CG9188(orf name) psi-mi:sept1_drome(display_long)|uniprotkb:DIFF6 protein homolog(gene name synonym)|uniprotkb:Protein innocent bystander(gene name synonym)|uniprotkb:CG1403(orf name)|uniprotkb:Sep1(gene name)|psi-mi:Sep1(display_short)|uniprotkb:Diff6(gene name synonym)|uniprotkb:iby(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874292 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_723235.2|flybase:FBgn0031878|ensemblmetazoa:FBgn0031878(gene)|ensemblmetazoa:FBtr0079359(transcript) ensemblmetazoa:FBgn0011710(gene)|ensemblmetazoa:FBtr0077198(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0007349"(cellularization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|refseq:NP_523430.1|flybase:FBgn0011710|dip:DIP-18454N pubmed:11884525(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Y7TWulZVmlMjvDTcutHydbyf2w87227 rogid:owbyZvFu8+uF3t60BTm9IqquTL47227 intact-crc:E4A1810692FA233F|rigid:3k/y9+3dLq5PRxj5xniVGHNY28k false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P54359 uniprotkb:P42207 intact:EBI-188936|uniprotkb:Q24092|uniprotkb:Q9VDK8|ensemblmetazoa:FBpp0083352 intact:EBI-120528|uniprotkb:Q9VRH5|uniprotkb:Q8IQ47|ensemblmetazoa:FBpp0076897 psi-mi:sept2_drome(display_long)|uniprotkb:Sep2(gene name)|psi-mi:Sep2(display_short)|uniprotkb:CG4173(orf name) psi-mi:sept1_drome(display_long)|uniprotkb:DIFF6 protein homolog(gene name synonym)|uniprotkb:Protein innocent bystander(gene name synonym)|uniprotkb:CG1403(orf name)|uniprotkb:Sep1(gene name)|psi-mi:Sep1(display_short)|uniprotkb:Diff6(gene name synonym)|uniprotkb:iby(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874296 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524417.1|flybase:FBgn0014029|dip:DIP-20060N|ensemblmetazoa:FBgn0014029(gene)|ensemblmetazoa:FBtr0083945(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007295"(growth of a germarium-derived egg chamber)|go:"GO:0007349"(cellularization)|go:"GO:0007444"(imaginal disc development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379 ensemblmetazoa:FBgn0011710(gene)|ensemblmetazoa:FBtr0077198(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0007349"(cellularization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|refseq:NP_523430.1|flybase:FBgn0011710|dip:DIP-18454N pubmed:11884525(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:yZOoGT0rH7z1Sm3rbziG/xiMNMg7227 rogid:owbyZvFu8+uF3t60BTm9IqquTL47227 intact-crc:CBFD8D264A09F8AA|rigid:pNP7UM3stt/IQql+2smqBFLhe6A false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KJV6 uniprotkb:P54359 intact:EBI-867875 intact:EBI-188936|uniprotkb:Q24092|uniprotkb:Q9VDK8|ensemblmetazoa:FBpp0083352 psi-mi:q7kjv6_drome(display_long)|uniprotkb:Uba2(gene name)|psi-mi:Uba2(display_short)|uniprotkb:CG7528(orf name) psi-mi:sept2_drome(display_long)|uniprotkb:Sep2(gene name)|psi-mi:Sep2(display_short)|uniprotkb:CG4173(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874300 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0029113|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033134"(ubiquitin activating enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR019572|interpro:IPR023318|interpro:IPR028077|interpro:IPR030661|interpro:IPR033127|interpro:IPR035985|interpro:IPR042449 refseq:NP_524417.1|flybase:FBgn0014029|dip:DIP-20060N|ensemblmetazoa:FBgn0014029(gene)|ensemblmetazoa:FBtr0083945(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007295"(growth of a germarium-derived egg chamber)|go:"GO:0007349"(cellularization)|go:"GO:0007444"(imaginal disc development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379 pubmed:11884525(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6hSWdsAvG5y2/bW1XcSHzO+1b0A7227 rogid:yZOoGT0rH7z1Sm3rbziG/xiMNMg7227 intact-crc:95413263598A3569|rigid:9AGFfnnMVo7wxC5Syxv5Gv1MBoE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q95SP2 uniprotkb:P54359 intact:EBI-116604|uniprotkb:Q9V9T8|ensemblmetazoa:FBpp0303146|ensemblmetazoa:FBpp0085201 intact:EBI-188936|uniprotkb:Q24092|uniprotkb:Q9VDK8|ensemblmetazoa:FBpp0083352 psi-mi:hrd1_drome(display_long)|uniprotkb:sip3(gene name)|psi-mi:sip3(display_short)|uniprotkb:CG1937(orf name)|uniprotkb:Syno(gene name synonym)|uniprotkb:Synoviolin(gene name synonym)|uniprotkb:Septin-interacting protein 3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HRD1(gene name synonym) psi-mi:sept2_drome(display_long)|uniprotkb:Sep2(gene name)|psi-mi:Sep2(display_short)|uniprotkb:CG4173(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874304 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651894.3|flybase:FBgn0039875|ensemblmetazoa:FBtr0085842(transcript)|ensemblmetazoa:FBtr0330113(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0036490"(regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|reactome:R-DME-5358346|ensemblmetazoa:FBgn0039875(gene)|refseq:NP_001263152.1 refseq:NP_524417.1|flybase:FBgn0014029|dip:DIP-20060N|ensemblmetazoa:FBgn0014029(gene)|ensemblmetazoa:FBtr0083945(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007295"(growth of a germarium-derived egg chamber)|go:"GO:0007349"(cellularization)|go:"GO:0007444"(imaginal disc development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379 pubmed:11884525(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6loL3X76VDus/yDgYDP5Kl/U3N47227 rogid:yZOoGT0rH7z1Sm3rbziG/xiMNMg7227 intact-crc:50BD1A4232F9604C|rigid:hF7YNnO7pjRphVr9teq3frlzcnI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q7KTL4 uniprotkb:P54359 intact:EBI-870738|ensemblmetazoa:FBpp0078987 intact:EBI-188936|uniprotkb:Q24092|uniprotkb:Q9VDK8|ensemblmetazoa:FBpp0083352 psi-mi:q7ktl4_drome(display_long)|uniprotkb:sip2(gene name)|psi-mi:sip2(display_short)|uniprotkb:Dmel\CG9188(gene name synonym)|uniprotkb:FIP(gene name synonym)|uniprotkb:fip(gene name synonym)|uniprotkb:CG9188(orf name)|uniprotkb:Dmel_CG9188(orf name) psi-mi:sept2_drome(display_long)|uniprotkb:Sep2(gene name)|psi-mi:Sep2(display_short)|uniprotkb:CG4173(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874308 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_723235.2|flybase:FBgn0031878|ensemblmetazoa:FBgn0031878(gene)|ensemblmetazoa:FBtr0079359(transcript) refseq:NP_524417.1|flybase:FBgn0014029|dip:DIP-20060N|ensemblmetazoa:FBgn0014029(gene)|ensemblmetazoa:FBtr0083945(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007295"(growth of a germarium-derived egg chamber)|go:"GO:0007349"(cellularization)|go:"GO:0007444"(imaginal disc development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379 pubmed:11884525(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Y7TWulZVmlMjvDTcutHydbyf2w87227 rogid:yZOoGT0rH7z1Sm3rbziG/xiMNMg7227 intact-crc:478B719D6E32F38C|rigid:b1WUhspSGyHCh00VHyf6t3MJy8g false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P26675 uniprotkb:P13368 intact:EBI-82070|uniprotkb:Q6AWF4|uniprotkb:Q8I067|uniprotkb:Q8I0F7|uniprotkb:Q8ITK2|uniprotkb:Q95TI8|uniprotkb:Q969D6|uniprotkb:Q9VJV9|ensemblmetazoa:FBpp0080118 intact:EBI-522166|uniprotkb:Q9TYI0|uniprotkb:Q9U5V7|uniprotkb:Q9VZ36|ensemblmetazoa:FBpp0073249 psi-mi:sos_drome(display_long)|uniprotkb:Sos(gene name)|psi-mi:Sos(display_short)|uniprotkb:CG7793(orf name) psi-mi:7less_drome(display_long)|uniprotkb:sev(gene name)|psi-mi:sev(display_short)|uniprotkb:HD-265(gene name synonym)|uniprotkb:CG18085(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874312 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476597.2|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR007125(Histone core)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR035899|interpro:IPR036964|rcsb pdb:1AZE|reactome:R-DME-112412|reactome:R-DME-1250347|reactome:R-DME-1433557|reactome:R-DME-1433559|reactome:R-DME-167044|reactome:R-DME-179812|reactome:R-DME-180336|reactome:R-DME-186763|reactome:R-DME-193648|reactome:R-DME-1963640|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2428933|reactome:R-DME-2730905|reactome:R-DME-2871796|reactome:R-DME-2871809|reactome:R-DME-375165|reactome:R-DME-416482|reactome:R-DME-5654688|reactome:R-DME-5654693|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5673001|reactome:R-DME-74749|reactome:R-DME-74751|reactome:R-DME-9013149|reactome:R-DME-9607240|ensemblmetazoa:FBgn0001965(gene)|ensemblmetazoa:FBtr0080541(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035997"(rhabdomere microvillus membrane)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0045500"(sevenless signaling pathway)|flybase:FBgn0001965|dip:DIP-22308N refseq:NP_511114.2|flybase:FBgn0003366|ensemblmetazoa:FBgn0003366(gene)|go:"GO:0045500"(sevenless signaling pathway)|ensemblmetazoa:FBtr0073393(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008288"(boss receptor activity)|go:"GO:0019199"(transmembrane receptor protein kinase activity)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0043235"(receptor complex)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116 pubmed:7725106(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:TxXgLxqhzkv9TdP1KrgoN7wEyFo7227 rogid:YpmSTbTsxz1LSM+oNtflAISXkIQ7227 intact-crc:013BEF2EB548DEBD|rigid:Y5mdEdPgeiGLxVETjxGLo/3+ptE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P19018 uniprotkb:Q9V3W7 intact:EBI-198424|uniprotkb:A4UZH1|uniprotkb:Q0E977|uniprotkb:Q9V734|ensemblmetazoa:FBpp0088562|ensemblmetazoa:FBpp0088946|ensemblmetazoa:FBpp0088947 intact:EBI-93356|intact:EBI-1628034|ensemblmetazoa:FBpp0082724|ensemblmetazoa:FBpp0293269 psi-mi:tra2_drome(display_long)|uniprotkb:tra2(gene name)|psi-mi:tra2(display_short)|uniprotkb:tra-2(gene name synonym)|uniprotkb:CG10128(orf name) psi-mi:q9v3w7_drome(display_long)|uniprotkb:SF2(gene name)|psi-mi:SF2(display_short)|uniprotkb:p28/SF2(gene name synonym)|uniprotkb:154911_at(gene name synonym)|uniprotkb:ASF(gene name synonym)|uniprotkb:Dmel\CG6987(gene name synonym)|uniprotkb:SRp30(gene name synonym)|uniprotkb:dASF(gene name synonym)|uniprotkb:dSF2(gene name synonym)|uniprotkb:dSRp30(gene name synonym)|uniprotkb:dmSF2(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:Dmel_CG6987(orf name)|uniprotkb:CG6987(orf name)|uniprotkb:cg6987(gene name synonym)|uniprotkb:SRSF1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874316 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476763.1|refseq:NP_476764.1|refseq:NP_476765.1|refseq:NP_476766.1|refseq:NP_599107.1|refseq:NP_995834.1|refseq:NP_995835.1|flybase:FBgn0003742|dip:DIP-17430N|ensemblmetazoa:FBgn0003742(gene)|ensemblmetazoa:FBtr0089617(transcript)|ensemblmetazoa:FBtr0089620(transcript)|ensemblmetazoa:FBtr0089621(transcript)|go:"GO:0000003"(reproduction)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0019101"(female somatic sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030237"(female sex determination)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-DME-6791226|reactome:R-DME-72163|reactome:R-DME-9013418|reactome:R-DME-9013422 flybase:FBgn0283477|refseq:NP_652611.1|refseq:NP_001247139.1|ensemblmetazoa:FBgn0283477(gene)|ensemblmetazoa:FBtr0083272(transcript)|ensemblmetazoa:FBtr0304727(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001178"(regulation of transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|reactome:R-DME-159236|reactome:R-DME-72163|reactome:R-DME-72165|reactome:R-DME-72187|reactome:R-DME-73856 pubmed:8261509(see-also)|pubmed:8124712(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:uL8i3jhKpNlSUIxgCb/9lb1L/1E7227 rogid:IxkPdVi2EeVb5mVcIaeGY7ptbTw7227 intact-crc:7156B04A9B533DC6|rigid:IwRKyMUic4HCPYZ1IyYqJUXUQgk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P49021 uniprotkb:P18431 intact:EBI-266295|uniprotkb:O44380|uniprotkb:Q8I037|uniprotkb:Q95U67|uniprotkb:Q9VQR6|uniprotkb:Q9VQR7|intact:EBI-3407510|uniprotkb:M9MRE9|uniprotkb:A4V040|uniprotkb:B7Z007|uniprotkb:B7Z008|uniprotkb:C9QPB7|uniprotkb:Q1WWF5|uniprotkb:Q59E16|intact:EBI-9944820|ensemblmetazoa:FBpp0077256|ensemblmetazoa:FBpp0305454 intact:EBI-242141|uniprotkb:O76881|uniprotkb:P23646|uniprotkb:Q27603|uniprotkb:Q27604|uniprotkb:Q27605|uniprotkb:Q8MRF7|uniprotkb:Q9NF42|uniprotkb:Q9U094|uniprotkb:Q9W4X3|ensemblmetazoa:FBpp0070449|ensemblmetazoa:FBpp0070451|ensemblmetazoa:FBpp0070452|ensemblmetazoa:FBpp0070453|ensemblmetazoa:FBpp0089158|ensemblmetazoa:FBpp0089162 psi-mi:tim_drome(display_long)|uniprotkb:tim(gene name)|psi-mi:tim(display_short)|uniprotkb:CG3234(orf name) psi-mi:sgg_drome(display_long)|uniprotkb:sgg(gene name)|psi-mi:sgg(display_short)|uniprotkb:zw3(gene name synonym)|uniprotkb:CG2621(orf name)|uniprotkb:Protein zeste-white 3(gene name synonym)|uniprotkb:gsk3(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874320 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_722914.3|flybase:FBgn0014396|refseq:NP_722912.3|refseq:NP_722913.3|refseq:NP_001014463.2|refseq:NP_001033872.2|refseq:NP_001137780.2|refseq:NP_001137781.2|refseq:NP_001188686.2|dip:DIP-29425N|ensemblmetazoa:FBgn0014396(gene)|ensemblmetazoa:FBtr0077567(transcript)|ensemblmetazoa:FBtr0333256(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003053"(circadian regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007617"(mating behavior)|go:"GO:0007620"(copulation)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008062"(eclosion rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009648"(photoperiodism)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0043111"(replication fork arrest)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0046957"(negative phototaxis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048478"(replication fork protection)|go:"GO:0048512"(circadian behavior)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR006906(Timeless protein)|interpro:IPR007725(Timeless C-terminal)|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 refseq:NP_476714.1|refseq:NP_476715.1|refseq:NP_476716.2|refseq:NP_599105.1|refseq:NP_726822.1|refseq:NP_726823.1|refseq:NP_996335.1|refseq:NP_996336.1|refseq:NP_996337.1|refseq:NP_996338.1|flybase:FBgn0003371|dip:DIP-39170N|ensemblmetazoa:FBgn0003371(gene)|ensemblmetazoa:FBtr0070466(transcript)|ensemblmetazoa:FBtr0070468(transcript)|ensemblmetazoa:FBtr0070469(transcript)|ensemblmetazoa:FBtr0070470(transcript)|ensemblmetazoa:FBtr0070472(transcript)|ensemblmetazoa:FBtr0070473(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007165"(signal transduction)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007507"(heart development)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008355"(olfactory learning)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0022416"(chaeta development)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030424"(axon)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035324"(female germline ring canal)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045169"(fusome)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046959"(habituation)|go:"GO:0048477"(oogenesis)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070884"(regulation of calcineurin-NFAT signaling cascade)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209387|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3371453|reactome:R-DME-399956|reactome:R-DME-432553|reactome:R-DME-4641262|reactome:R-DME-5610785 pubmed:11440719(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:wdN/j17nXo6XpfHUGGSo5zYNhog7227 rogid:sUjAtUAobW55mTZBsRiQg0K1U9o7227 intact-crc:359514761CF6972E|rigid:+57MkpBiGuS38M+LpYmbjQS/uqo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18475 uniprotkb:Q24080 intact:EBI-195402|uniprotkb:A8DY54|uniprotkb:A8DY56|uniprotkb:Q9V4R2|ensemblmetazoa:FBpp0088012 intact:EBI-869415 psi-mi:torso_drome(display_long)|uniprotkb:tor(gene name)|psi-mi:tor(display_short)|uniprotkb:CG1389(orf name) psi-mi:q24080_drome(display_long)|uniprotkb:Shc(gene name)|psi-mi:Shc(display_short)|uniprotkb:shc(gene name synonym)|uniprotkb:CG3715(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874324 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001097212.2|refseq:NP_476762.1|flybase:FBgn0003733|ensemblmetazoa:FBgn0003733(gene)|ensemblmetazoa:FBtr0088938(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007278"(pole cell fate determination)|go:"GO:0007280"(pole cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0046957"(negative phototaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116 flybase:FBgn0015296|go:"GO:0005886"(plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000980(SH2 motif)|interpro:IPR006019("Phosphotyrosine interaction (PID or PI)")|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035676|interpro:IPR036860 pubmed:10882065(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xto08nbumwFlew52tyO4IgeMEqs7227 rogid:2kguXmpfINpqc8t7N5is718hP0U7227 intact-crc:B4AEAC3FD039AE6F|rigid:R4n8u52MFKBezb4EIW8GbllxXXw false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O15945 uniprotkb:P05709 intact:EBI-172695|uniprotkb:O16167|uniprotkb:O44082|uniprotkb:Q24461|uniprotkb:Q9VHI2|intact:EBI-3417363|ensemblmetazoa:FBpp0081483|ensemblmetazoa:FBpp0307731 intact:EBI-88929|uniprotkb:O96521|uniprotkb:Q7KSL7|uniprotkb:Q8MQI7|uniprotkb:Q9VFZ3|intact:EBI-3426277 psi-mi:arnt_drome(display_long)|uniprotkb:tgo(gene name)|psi-mi:tgo(display_short)|uniprotkb:ARNT(gene name synonym)|uniprotkb:HIF-1-beta(gene name synonym)|uniprotkb:CG11987(orf name)|uniprotkb:Protein tango(gene name synonym)|uniprotkb:Hypoxia-inducible factor 1-beta(gene name synonym) psi-mi:sim_drome(display_long)|uniprotkb:sim(gene name)|psi-mi:sim(display_short)|uniprotkb:CG7771(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874328 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_731308.1|flybase:FBgn0264075|refseq:NP_001262397.1|ensemblmetazoa:FBgn0264075(gene)|ensemblmetazoa:FBtr0082005(transcript)|ensemblmetazoa:FBtr0336755(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008347"(glial cell migration)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0017022"(myosin binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048736"(appendage development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-DME-1234158|reactome:R-DME-8937144 refseq:NP_524340.2|refseq:NP_731771.3|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|interpro:IPR001067(Nuclear translocator)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007398"(ectoderm development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007418"(ventral midline development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007420"(brain development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0040011"(locomotion)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000014(PAS)|go:"GO:0003700"(DNA-binding transcription factor activity)|flybase:FBgn0004666 pubmed:9409674(see-also)|pubmed:9521898(see-also)|pubmed:9284047(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:QfQjxuOMC66M3wNk0uC0IggqKbI7227 rogid:Xj4MTmDPyNDCBHuTSv9zZgIfvO07227 intact-crc:32C87A1A5C65DEC9|rigid:/871kRae5YaM4HgRKqZZaD0rJ+8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P19339 uniprotkb:Q5BI58 intact:EBI-199576|uniprotkb:P19340|uniprotkb:Q0KHV2|uniprotkb:Q26466|uniprotkb:Q2MGN7|uniprotkb:Q2MGN8|uniprotkb:Q2MGN9|uniprotkb:Q2MGP1|uniprotkb:Q7KVU6|uniprotkb:Q7YZ92|uniprotkb:Q8IRQ1|uniprotkb:Q99141|uniprotkb:Q9TYF5|uniprotkb:Q9W3S6|uniprotkb:A4V435|uniprotkb:A4V437|uniprotkb:A4V434|uniprotkb:A4V436|uniprotkb:C9QP40|uniprotkb:D0IQK2|uniprotkb:D3PFI6|uniprotkb:E1JJI8|uniprotkb:E1JJI9|uniprotkb:E1JJJ0|uniprotkb:E1JJJ2|uniprotkb:E1JJJ3|ensemblmetazoa:FBpp0303697|ensemblmetazoa:FBpp0303704|ensemblmetazoa:FBpp0303710 intact:EBI-870744 psi-mi:sxl_drome(display_long)|uniprotkb:Sxl(gene name)|psi-mi:Sxl(display_short)|uniprotkb:Sx1(gene name synonym)|uniprotkb:CG43770(orf name) psi-mi:q5bi58_drome(display_long)|uniprotkb:Polr3E(gene name)|psi-mi:Polr3E(display_short)|uniprotkb:Sin(gene name synonym)|uniprotkb:CG10582(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874332 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_727161.3|refseq:NP_001027062.1|refseq:NP_001027063.1|refseq:NP_001027064.1|refseq:NP_001027065.1|refseq:NP_001027066.1|refseq:NP_001162686.1|refseq:NP_001162687.1|refseq:NP_001162688.1|refseq:NP_001162689.1|refseq:NP_001162690.1|refseq:NP_524791.3|refseq:NP_727160.2|refseq:NP_727162.2|refseq:NP_727163.2|refseq:NP_727164.2|refseq:NP_727165.2|refseq:NP_727166.2|refseq:NP_727167.2|refseq:NP_727168.1|refseq:NP_001259305.1|refseq:NP_001259306.1|flybase:FBgn0264270|dip:DIP-44607N|ensemblmetazoa:FBgn0264270(gene)|ensemblmetazoa:FBtr0331255(transcript)|ensemblmetazoa:FBtr0331262(transcript)|ensemblmetazoa:FBtr0331268(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007530"(sex determination)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0007548"(sex differentiation)|go:"GO:0007549"(dosage compensation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0009994"(oocyte differentiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018993"(somatic sex determination)|go:"GO:0030237"(female sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990399"(epithelium regeneration)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006546(Sex-lethal splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P19339|rcsb pdb:1B7F|rcsb pdb:1SXL|rcsb pdb:2SXL|rcsb pdb:3SXL|rcsb pdb:4QQB flybase:FBgn0028402|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0006351"(transcription, DNA-templated)|interpro:IPR006886(Sin-like protein conserved region) pubmed:10521666(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:OOLyyjkFbL8POQarQfx8Yhy8SV47227 rogid:yQ2Q0DiBwh9DwQWIG2nZqVkADRk7227 intact-crc:8D1DF1DB41A76E2C|rigid:/IWLHzW1Ckk6u2GpBdd/0dsYbw0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q95RS0 uniprotkb:O17142 intact:EBI-869358 intact:EBI-870679 psi-mi:q95rs0_drome(display_long)|uniprotkb:Smr(gene name)|psi-mi:Smr(display_short)|uniprotkb:CG4013(orf name) psi-mi:o17142_drome(display_long)|uniprotkb:Sin3A(gene name)|psi-mi:Sin3A(display_short)|uniprotkb:CG8815(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874336 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0265523|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0042826"(histone deacetylase binding) flybase:FBgn0022764|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016580"(Sin3 complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035220"(wing disc development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774 pubmed:10488333(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:o8+vwhYspxfL0sTV2NiKCmIe1Jk7227 rogid:EYjzMyBlpsi6fRLtizbsQZgp96o7227 intact-crc:684365478ED56A0F|rigid:1ISQF2xUD2ErBLXbq+GWw5ENiqY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P17133 uniprotkb:Q9Y103 intact:EBI-167395|uniprotkb:Q9VM56|uniprotkb:Q564D5|ensemblmetazoa:FBpp0078983|ensemblmetazoa:FBpp0303793 intact:EBI-174432|intact:EBI-501125|uniprotkb:Q9NHN7|ensemblmetazoa:FBpp0078765|ensemblmetazoa:FBpp0311644 psi-mi:ru17_drome(display_long)|uniprotkb:snRNP-U1-70K(gene name)|psi-mi:snRNP-U1-70K(display_short)|uniprotkb:snRNP27D(gene name synonym)|uniprotkb:CG8749(orf name)|uniprotkb:snRNP70K(gene name synonym) psi-mi:tfp11_drome(display_long)|uniprotkb:sip1(gene name)|psi-mi:sip1(display_short)|uniprotkb:stip-1(gene name synonym)|uniprotkb:CG7238(orf name)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874340 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0016978(gene)|ensemblmetazoa:FBtr0079355(transcript)|ensemblmetazoa:FBtr0331375(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048477"(oogenesis)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR022023|interpro:IPR034143|interpro:IPR035979|rcsb pdb:2BN5|reactome:R-DME-72163|refseq:NP_477205.1|flybase:FBgn0016978|refseq:NP_001260173.1|dip:DIP-19840N refseq:NP_524725.2|flybase:FBgn0024191|refseq:NP_001285636.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|ensemblmetazoa:FBgn0024191(gene)|ensemblmetazoa:FBtr0079134(transcript)|ensemblmetazoa:FBtr0345545(transcript)|go:"GO:0000390"(spliceosomal complex disassembly) pubmed:9447963(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:ko80lVqh0vg+4j/uZ/ofuuJox0A7227 rogid:PJxaiEhZk9uaagQ6GWSK7ryjojU7227 intact-crc:98F30327CD557AE3|rigid:k9Kh78s8rJyOl+sY9bKuNKp5Wt4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O44382 uniprotkb:O77430 intact:EBI-869364 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 psi-mi:o44382_drome(display_long)|uniprotkb:slmb(gene name)|psi-mi:slmb(display_short)|uniprotkb:slimb(gene name synonym)|uniprotkb:CG3412(orf name) psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874348 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283468|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-432524 refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 pubmed:11500045(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:hKsZL6X4sxi/Zu4RDHlAV5IoZ2o7227 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 intact-crc:1D7C1258E04481C7|rigid:FgcOlzakZiuaWBwc/cbAi17hHRs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24574 uniprotkb:Q02637 intact:EBI-189528|uniprotkb:A4V1I7|uniprotkb:Q95TM9|uniprotkb:Q9VRP1|ensemblmetazoa:FBpp0076802|ensemblmetazoa:FBpp0076803 intact:EBI-158748|ensemblmetazoa:FBpp0072179|ensemblmetazoa:FBpp0308452|uniprotkb:Q9W183 psi-mi:ubpe_drome(display_long)|uniprotkb:Usp47(gene name)|psi-mi:Usp47(display_short)|uniprotkb:Ubiquitin thioesterase 47(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 47(gene name synonym)|uniprotkb:Ubp64E(gene name synonym)|uniprotkb:CG5486(orf name) psi-mi:cebp_drome(display_long)|uniprotkb:slbo(gene name)|psi-mi:slbo(display_short)|uniprotkb:Slow border cell protein(gene name synonym)|uniprotkb:CG4354(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874352 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_996001.2|refseq:NP_523937.2|refseq:NP_729087.1|flybase:FBgn0016756|ensemblmetazoa:FBgn0016756(gene)|ensemblmetazoa:FBtr0077095(transcript)|ensemblmetazoa:FBtr0077096(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031935"(obsolete regulation of chromatin silencing)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045874"(positive regulation of sevenless signaling pathway)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765 go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|ensemblmetazoa:FBtr0072272(transcript)|ensemblmetazoa:FBtr0339359(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|reactome:R-DME-2559582|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007298"(border follicle cell migration)|reactome:R-DME-9616222|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensemblmetazoa:FBgn0005638(gene)|refseq:NP_523843.1|flybase:FBgn0005638|refseq:NP_001286836.1 pubmed:10949024(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:9RrCujIogTnHBM43bAQlfNnMfMw7227 rogid:C7L0uqKlyAdoyU+APlJM2Tw8jso7227 intact-crc:27AF905CFFC70278|rigid:2ItZ+PbOqfR1ABpnMd1AtBXh+t0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9V3Z1 uniprotkb:Q02637 intact:EBI-113217|ensemblmetazoa:FBpp0077893 intact:EBI-158748|ensemblmetazoa:FBpp0072179|ensemblmetazoa:FBpp0308452|uniprotkb:Q9W183 psi-mi:trib_drome(display_long)|uniprotkb:trbl(gene name)|psi-mi:trbl(display_short)|uniprotkb:CG5408(orf name) psi-mi:cebp_drome(display_long)|uniprotkb:slbo(gene name)|psi-mi:slbo(display_short)|uniprotkb:Slow border cell protein(gene name synonym)|uniprotkb:CG4354(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874356 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524672.1|flybase:FBgn0028978|ensemblmetazoa:FBgn0028978(gene)|ensemblmetazoa:FBtr0078235(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048640"(negative regulation of developmental growth)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024104|reactome:R-DME-1257604|reactome:R-DME-165158|reactome:R-DME-199418|reactome:R-DME-389357|reactome:R-DME-5218920 go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|ensemblmetazoa:FBtr0072272(transcript)|ensemblmetazoa:FBtr0339359(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|reactome:R-DME-2559582|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007298"(border follicle cell migration)|reactome:R-DME-9616222|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensemblmetazoa:FBgn0005638(gene)|refseq:NP_523843.1|flybase:FBgn0005638|refseq:NP_001286836.1 pubmed:10949024(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:x2UxpNbqZSEYO2ew/qidAvtKumE7227 rogid:C7L0uqKlyAdoyU+APlJM2Tw8jso7227 intact-crc:9CD840E301BBD6A9|rigid:LM3O50UO3GipVNnAQmgO5j1Vmg0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P47825 uniprotkb:Q02637 intact:EBI-277958|uniprotkb:P49845|uniprotkb:Q0E8E3|uniprotkb:Q1LZ31|uniprotkb:Q8T9E0|uniprotkb:Q9VUY7|ensemblmetazoa:FBpp0075205|ensemblmetazoa:FBpp0075206|ensemblmetazoa:FBpp0291125|ensemblmetazoa:FBpp0311865 intact:EBI-158748|ensemblmetazoa:FBpp0072179|ensemblmetazoa:FBpp0308452|uniprotkb:Q9W183 psi-mi:taf4_drome(display_long)|uniprotkb:Transcription initiation factor TFIID 110 kDa subunit(gene name synonym)|uniprotkb:110 kDa TBP-associated factor(gene name synonym)|uniprotkb:Taf4(gene name)|psi-mi:Taf4(display_short)|uniprotkb:TAF110(gene name synonym)|uniprotkb:CG5444(orf name) psi-mi:cebp_drome(display_long)|uniprotkb:slbo(gene name)|psi-mi:slbo(display_short)|uniprotkb:Slow border cell protein(gene name synonym)|uniprotkb:CG4354(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874360 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_788511.1|refseq:NP_996101.1|flybase:FBgn0010280|refseq:NP_001287077.1|refseq:NP_001163453.1|refseq:NP_524102.1|refseq:NP_730109.1|dip:DIP-237N|ensemblmetazoa:FBgn0010280(gene)|ensemblmetazoa:FBtr0075448(transcript)|ensemblmetazoa:FBtr0075449(transcript)|ensemblmetazoa:FBtr0301911(transcript)|ensemblmetazoa:FBtr0345951(transcript)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR007900(Transcription initiation factor TFIID component TAF4)|interpro:IPR009072(Histone-fold)|interpro:IPR037249|mint:P47825|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|ensemblmetazoa:FBtr0072272(transcript)|ensemblmetazoa:FBtr0339359(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|reactome:R-DME-2559582|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007298"(border follicle cell migration)|reactome:R-DME-9616222|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensemblmetazoa:FBgn0005638(gene)|refseq:NP_523843.1|flybase:FBgn0005638|refseq:NP_001286836.1 pubmed:9512492(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KMwgcLywcp/YxxTLBjtmqXNPhdo7227 rogid:C7L0uqKlyAdoyU+APlJM2Tw8jso7227 intact-crc:85F227BF775BAB1B|rigid:IK+0g9L5LtkiRz85BgkaF8TKmE0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20153 uniprotkb:Q95RS0 intact:EBI-149021|uniprotkb:Q9W535|ensemblmetazoa:FBpp0070332|ensemblmetazoa:FBpp0305937 intact:EBI-869358 psi-mi:usp_drome(display_long)|uniprotkb:usp(gene name)|psi-mi:usp(display_short)|uniprotkb:Cf1(gene name synonym)|uniprotkb:NR2B4(gene name synonym)|uniprotkb:CG4380(orf name)|uniprotkb:XR2C(gene name synonym)|uniprotkb:Chorion factor 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 4(gene name synonym) psi-mi:q95rs0_drome(display_long)|uniprotkb:Smr(gene name)|psi-mi:Smr(display_short)|uniprotkb:CG4013(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874372 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476781.1|flybase:FBgn0003964|refseq:NP_001259168.1|dip:DIP-645N|ensemblmetazoa:FBgn0003964(gene)|ensemblmetazoa:FBtr0070346(transcript)|ensemblmetazoa:FBtr0333803(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|reactome:R-DME-9707564|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006697"(ecdysone biosynthetic process)|go:"GO:0007281"(germ cell development)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007552"(metamorphosis)|go:"GO:0008230"(ecdysone receptor holocomplex)|reactome:R-DME-9623433|go:"GO:0008232"(activator ecdysone receptor complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016319"(mushroom body development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0035073"(pupariation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0042562"(hormone binding)|go:"GO:0042594"(response to starvation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071390"(cellular response to ecdysone)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1HG4|rcsb pdb:1R0O|rcsb pdb:2HAN|reactome:R-DME-159418|reactome:R-DME-200425|reactome:R-DME-204174|reactome:R-DME-381340|reactome:R-DME-383280|reactome:R-DME-400206|reactome:R-DME-5362517|reactome:R-DME-9029569|reactome:R-DME-9616222 flybase:FBgn0265523|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0042826"(histone deacetylase binding) pubmed:10488333(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:amASW54ZH6dtdZULbgr9lt4GbBE7227 rogid:o8+vwhYspxfL0sTV2NiKCmIe1Jk7227 intact-crc:D9E76C11B6DDEB88|rigid:fiX0Q58DXqjgJ7706YwoSS++EBA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42282 uniprotkb:O97102 intact:EBI-77008|uniprotkb:A4V3Q3|uniprotkb:Q0KHY0|uniprotkb:Q1LZ43|uniprotkb:Q24313|uniprotkb:Q9V9V2|ensemblmetazoa:FBpp0085186|ensemblmetazoa:FBpp0085188|ensemblmetazoa:FBpp0085190|ensemblmetazoa:FBpp0292319 intact:EBI-114439|ensemblmetazoa:FBpp0078984|ensemblmetazoa:FBpp0312327 psi-mi:ttka_drome(display_long)|uniprotkb:ttk(gene name)|psi-mi:ttk(display_short)|uniprotkb:FTZ-F2(gene name synonym)|uniprotkb:CG1856(orf name)|uniprotkb:Tramtrack p88(gene name synonym)|uniprotkb:Repressor protein fushi tarazu(gene name synonym) psi-mi:o97102_drome(display_long)|uniprotkb:smt3(gene name)|psi-mi:smt3(display_short)|uniprotkb:Smt3(gene name synonym)|uniprotkb:DmSUMO-1(gene name synonym)|uniprotkb:Dm0342(gene name synonym)|uniprotkb:DmSmt3(gene name synonym)|uniprotkb:Dmel\CG4494(gene name synonym)|uniprotkb:Dmsmt3(gene name synonym)|uniprotkb:SMT3(gene name synonym)|uniprotkb:SUMO(gene name synonym)|uniprotkb:Sumo(gene name synonym)|uniprotkb:"anon-EST:Posey240"(gene name synonym)|uniprotkb:dSmt3(gene name synonym)|uniprotkb:dsmt3(gene name synonym)|uniprotkb:"l(2)04493"(gene name synonym)|uniprotkb:"l(2)SH0182"(gene name synonym)|uniprotkb:"l(2)SH2 0182"(gene name synonym)|uniprotkb:CG4494(orf name)|uniprotkb:sumo(gene name synonym)|uniprotkb:Dmel_CG4494(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874376 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189329.1|refseq:NP_733443.1|refseq:NP_733444.1|refseq:NP_733445.1|flybase:FBgn0003870|ensemblmetazoa:FBgn0003870(gene)|ensemblmetazoa:FBtr0085825(transcript)|ensemblmetazoa:FBtr0085827(transcript)|ensemblmetazoa:FBtr0085829(transcript)|ensemblmetazoa:FBtr0303227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031208"(POZ domain binding)|go:"GO:0035001"(dorsal trunk growth, open tracheal system)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035151"(regulation of tube size, open tracheal system)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042682"(regulation of compound eye cone cell fate specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045677"(negative regulation of R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048053"(R1/R6 development)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048750"(compound eye corneal lens morphogenesis)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 refseq:NP_477411.1|go:"GO:0000940"(outer kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|ensemblmetazoa:FBgn0264922(gene)|ensemblmetazoa:FBtr0079356(transcript)|ensemblmetazoa:FBtr0346716(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016925"(protein sumoylation)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030496"(midbody)|go:"GO:0031386"(protein tag)|go:"GO:0035073"(pupariation)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:O97102|rcsb pdb:2K1F|reactome:R-DME-196791|reactome:R-DME-3065679|reactome:R-DME-3108214|reactome:R-DME-3232118|reactome:R-DME-3899300|reactome:R-DME-4090294|reactome:R-DME-4551638|reactome:R-DME-4570464|reactome:R-DME-4615885|reactome:R-DME-4755510|reactome:R-DME-5696395|refseq:NP_001303312.1|flybase:FBgn0264922 pubmed:10629064(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:k0MeF2/ch3ddqz7uLHjP8aeJwoI7227 rogid:fqo3Y86DDI0SsWGEfanaOs8qJlk7227 intact-crc:C0C9C0FE1E31EB18|rigid:e8wECVO0p6pcB8UCnNbyJOqKdmc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q86P91 uniprotkb:Q23983 intact:EBI-870760|ensemblmetazoa:FBpp0077022 intact:EBI-195132|intact:EBI-1627756|uniprotkb:Q541G5|ensemblmetazoa:FBpp0074609 psi-mi:q86p91_drome(display_long)|uniprotkb:Syx16(gene name)|psi-mi:Syx16(display_short)|uniprotkb:CG1467(orf name) psi-mi:snap_drome(display_long)|uniprotkb:alphaSnap(gene name)|psi-mi:alphaSnap(display_short)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein(gene name synonym)|uniprotkb:Snap(gene name synonym)|uniprotkb:CG6625(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874380 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0031106|ensemblmetazoa:FBgn0031106(gene)|ensemblmetazoa:FBtr0077330(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048278"(vesicle docking)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673 refseq:NP_524180.1|flybase:FBgn0250791|dip:DIP-19393N|ensemblmetazoa:FBgn0250791(gene)|ensemblmetazoa:FBtr0074840(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0048526"(imaginal disc-derived wing expansion)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-DME-204005|reactome:R-DME-6807878|reactome:R-DME-6811434|reactome:R-DME-6811438|reactome:R-DME-6811440 pubmed:12414991(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:fbF2zl4Do3qLz31Vn+L/HfthV7k7227 rogid:39JW+aTXo/CNVYdkgJ59P59qgHs7227 intact-crc:65DD3F9FFDDB7572|rigid:QGGKNG0VrZvyx8qXCtH76KzHHag false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24547 uniprotkb:Q9VH76 intact:EBI-135062|intact:EBI-1628359|uniprotkb:Q9TX14|uniprotkb:Q9VCD7|ensemblmetazoa:FBpp0083973|ensemblmetazoa:FBpp0352246 intact:EBI-164224|intact:EBI-1628387|ensemblmetazoa:FBpp0081641 psi-mi:stx1a_drome(display_long)|uniprotkb:Syx1A(gene name)|psi-mi:Syx1A(display_short)|uniprotkb:syx-1A(gene name synonym)|uniprotkb:CG31136(orf name)|uniprotkb:dSynt1(gene name synonym) psi-mi:q9vh76_drome(display_long)|uniprotkb:Snap24(gene name)|psi-mi:Snap24(display_short)|uniprotkb:SNAP-24(gene name synonym)|uniprotkb:Dmel\CG9474(gene name synonym)|uniprotkb:SNAP-25b(gene name synonym)|uniprotkb:SNAP24(gene name synonym)|uniprotkb:Snap25b(gene name synonym)|uniprotkb:Dmel_CG9474(orf name)|uniprotkb:CG9474(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874384 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524475.1|flybase:FBgn0013343|refseq:NP_001303545.1|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-449836|reactome:R-DME-888590|reactome:R-DME-9609523|ensemblmetazoa:FBgn0013343(gene)|go:"GO:0007482"(haltere development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|ensemblmetazoa:FBtr0084588(transcript)|ensemblmetazoa:FBtr0392904(transcript)|go:"GO:0000149"(SNARE binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|reactome:R-DME-181429|reactome:R-DME-181430|go:"GO:0007349"(cellularization)|dip:DIP-19389N refseq:NP_524298.1|ensemblmetazoa:FBgn0266720(gene)|ensemblmetazoa:FBtr0082163(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|reactome:R-DME-181429|reactome:R-DME-181430|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-449836|reactome:R-DME-6798695|reactome:R-DME-888590|flybase:FBgn0266720 pubmed:11058092(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xlJYHz+B+bylWpjl2G3IUBud/5s7227 rogid:8VPeSO+RrGmuCjuOAALatcS62IE7227 intact-crc:62CA43A242937324|rigid:qvX+SFJ+2jgIp3uQ6oz3I9FjRw8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24547 uniprotkb:P36975 intact:EBI-135062|intact:EBI-1628359|uniprotkb:Q9TX14|uniprotkb:Q9VCD7|ensemblmetazoa:FBpp0083973|ensemblmetazoa:FBpp0352246 intact:EBI-870775|uniprotkb:F3YD56|uniprotkb:Q5LJU6|uniprotkb:Q7PLV2|ensemblmetazoa:FBpp0110435 psi-mi:stx1a_drome(display_long)|uniprotkb:Syx1A(gene name)|psi-mi:Syx1A(display_short)|uniprotkb:syx-1A(gene name synonym)|uniprotkb:CG31136(orf name)|uniprotkb:dSynt1(gene name synonym) psi-mi:snp25_drome(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:CG40452(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874388 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524475.1|flybase:FBgn0013343|refseq:NP_001303545.1|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-449836|reactome:R-DME-888590|reactome:R-DME-9609523|ensemblmetazoa:FBgn0013343(gene)|go:"GO:0007482"(haltere development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|ensemblmetazoa:FBtr0084588(transcript)|ensemblmetazoa:FBtr0392904(transcript)|go:"GO:0000149"(SNARE binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|reactome:R-DME-181429|reactome:R-DME-181430|go:"GO:0007349"(cellularization)|dip:DIP-19389N refseq:NP_001036642.2|refseq:NP_001036641.1|flybase:FBgn0011288|dip:DIP-23273N|ensemblmetazoa:FBgn0011288(gene)|ensemblmetazoa:FBtr0111143(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048489"(synaptic vesicle transport)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|reactome:R-DME-181429|reactome:R-DME-181430|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-449836|reactome:R-DME-6798695|reactome:R-DME-888590|reactome:R-DME-8980692|reactome:R-DME-9013149|reactome:R-DME-9013406|reactome:R-DME-9035034 pubmed:10575024(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xlJYHz+B+bylWpjl2G3IUBud/5s7227 rogid:kgz1W2uhZVTCSKgWKeanJVcaYNI7227 intact-crc:C1829946CE54D64B|rigid:IxLXGIJyni5VbM/jWfuzUjxOsTo false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P18489 uniprotkb:P36975 intact:EBI-497912|uniprotkb:Q8MKX1|uniprotkb:Q9V5I6|uniprotkb:Q3HKB4|uniprotkb:B7YZD5|uniprotkb:B7YZD6|ensemblmetazoa:FBpp0271782 intact:EBI-870775|uniprotkb:F3YD56|uniprotkb:Q5LJU6|uniprotkb:Q7PLV2|ensemblmetazoa:FBpp0110435 psi-mi:syb_drome(display_long)|uniprotkb:Syb(gene name)|psi-mi:Syb(display_short)|uniprotkb:CG12210(orf name) psi-mi:snp25_drome(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:CG40452(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874392 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001286278.1|refseq:NP_001137633.1|refseq:NP_001137634.1|refseq:NP_523680.1|refseq:NP_724906.1|flybase:FBgn0003660|ensemblmetazoa:FBgn0003660(gene)|ensemblmetazoa:FBtr0273274(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0043005"(neuron projection)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|reactome:R-DME-181429|reactome:R-DME-181430|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-432720|reactome:R-DME-432722|reactome:R-DME-449836|reactome:R-DME-6798695|reactome:R-DME-6811440|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-888590|reactome:R-DME-8980692|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-9013405|reactome:R-DME-9013406|reactome:R-DME-9013407|reactome:R-DME-9035034|reactome:R-DME-9609523 refseq:NP_001036642.2|refseq:NP_001036641.1|flybase:FBgn0011288|dip:DIP-23273N|ensemblmetazoa:FBgn0011288(gene)|ensemblmetazoa:FBtr0111143(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048489"(synaptic vesicle transport)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|reactome:R-DME-181429|reactome:R-DME-181430|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-449836|reactome:R-DME-6798695|reactome:R-DME-888590|reactome:R-DME-8980692|reactome:R-DME-9013149|reactome:R-DME-9013406|reactome:R-DME-9035034 pubmed:9728921(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:0GVct78wgjr8E88ZYPr03wY7yr87227 rogid:kgz1W2uhZVTCSKgWKeanJVcaYNI7227 intact-crc:0D265B80FA277A1C|rigid:zO6u1pDRYruWcCv4K5NO3F1TU1c false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9U1H5 uniprotkb:Q9VU59 intact:EBI-870788 intact:EBI-160783|ensemblmetazoa:FBpp0075576 psi-mi:q9u1h5_drome(display_long)|uniprotkb:SoxN(gene name)|psi-mi:SoxN(display_short)|uniprotkb:CG18024(orf name) psi-mi:q9vu59_drome(display_long)|uniprotkb:SNCF(gene name)|psi-mi:SNCF(display_short)|uniprotkb:"BcDNA:RE54375"(gene name synonym)|uniprotkb:Dmel\CG14112(gene name synonym)|uniprotkb:HL6(gene name synonym)|uniprotkb:SCNF(gene name synonym)|uniprotkb:Dmel_CG14112(orf name)|uniprotkb:CG14112(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874396 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0029123|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR036910 refseq:NP_648635.1|flybase:FBgn0036349|ensemblmetazoa:FBgn0036349(gene)|ensemblmetazoa:FBtr0075840(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0032879"(regulation of localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR007970(Protein of unknown function DUF733) pubmed:14597169(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:EQ+lwDAkOgCCNLorC35fTbPtZLw7227 rogid:2dwX9tq8fetR/XZXlUpSyq8iofo7227 intact-crc:10BEB1411088BC5C|rigid:keMZsKaiEowj8VJ80jCJw7rn4yk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9V4Q8 uniprotkb:P43332 intact:EBI-130179|ensemblmetazoa:FBpp0088015 intact:EBI-174177|uniprotkb:Q9W4D7|ensemblmetazoa:FBpp0070716 psi-mi:ru2a_drome(display_long)|uniprotkb:U2A(gene name)|psi-mi:U2A(display_short)|uniprotkb:CG1406(orf name) psi-mi:snrpa_drome(display_long)|uniprotkb:snf(gene name)|psi-mi:snf(display_short)|uniprotkb:D25(gene name synonym)|uniprotkb:liz(gene name synonym)|uniprotkb:"fs(1)1621"(gene name synonym)|uniprotkb:CG4528(orf name)|uniprotkb:Sex determination protein snf(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874400 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610315.1|flybase:FBgn0033210|ensemblmetazoa:FBgn0033210(gene)|ensemblmetazoa:FBtr0088941(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|interpro:IPR044640|rcsb pdb:6F4G|rcsb pdb:6F4J|reactome:R-DME-72163 refseq:NP_511045.1|flybase:FBgn0003449|dip:DIP-23676N|ensemblmetazoa:FBgn0003449(gene)|ensemblmetazoa:FBtr0070748(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0007539"(primary sex determination, soma)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0019099"(female germ-line sex determination)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035614"(snRNA stem-loop binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097158"(pre-mRNA intronic pyrimidine-rich binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:2AYM|rcsb pdb:2B0G|rcsb pdb:2K3K|rcsb pdb:6F4G|rcsb pdb:6F4H|rcsb pdb:6F4I|rcsb pdb:6F4J|reactome:R-DME-72163 pubmed:11557816(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:dzX+JQpDMjcQ16yMqooUL8ZkVoI7227 rogid:f092+a2bHKIbT6VQoJMPYguAKGk7227 intact-crc:15D7E6890774AD9B|rigid:0sBv0uy+vjIayVRchs4cFkZ1rNI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P19339 uniprotkb:P43332 intact:EBI-199576|uniprotkb:P19340|uniprotkb:Q0KHV2|uniprotkb:Q26466|uniprotkb:Q2MGN7|uniprotkb:Q2MGN8|uniprotkb:Q2MGN9|uniprotkb:Q2MGP1|uniprotkb:Q7KVU6|uniprotkb:Q7YZ92|uniprotkb:Q8IRQ1|uniprotkb:Q99141|uniprotkb:Q9TYF5|uniprotkb:Q9W3S6|uniprotkb:A4V435|uniprotkb:A4V437|uniprotkb:A4V434|uniprotkb:A4V436|uniprotkb:C9QP40|uniprotkb:D0IQK2|uniprotkb:D3PFI6|uniprotkb:E1JJI8|uniprotkb:E1JJI9|uniprotkb:E1JJJ0|uniprotkb:E1JJJ2|uniprotkb:E1JJJ3|ensemblmetazoa:FBpp0303697|ensemblmetazoa:FBpp0303704|ensemblmetazoa:FBpp0303710 intact:EBI-174177|uniprotkb:Q9W4D7|ensemblmetazoa:FBpp0070716 psi-mi:sxl_drome(display_long)|uniprotkb:Sxl(gene name)|psi-mi:Sxl(display_short)|uniprotkb:Sx1(gene name synonym)|uniprotkb:CG43770(orf name) psi-mi:snrpa_drome(display_long)|uniprotkb:snf(gene name)|psi-mi:snf(display_short)|uniprotkb:D25(gene name synonym)|uniprotkb:liz(gene name synonym)|uniprotkb:"fs(1)1621"(gene name synonym)|uniprotkb:CG4528(orf name)|uniprotkb:Sex determination protein snf(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874404 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_727161.3|refseq:NP_001027062.1|refseq:NP_001027063.1|refseq:NP_001027064.1|refseq:NP_001027065.1|refseq:NP_001027066.1|refseq:NP_001162686.1|refseq:NP_001162687.1|refseq:NP_001162688.1|refseq:NP_001162689.1|refseq:NP_001162690.1|refseq:NP_524791.3|refseq:NP_727160.2|refseq:NP_727162.2|refseq:NP_727163.2|refseq:NP_727164.2|refseq:NP_727165.2|refseq:NP_727166.2|refseq:NP_727167.2|refseq:NP_727168.1|refseq:NP_001259305.1|refseq:NP_001259306.1|flybase:FBgn0264270|dip:DIP-44607N|ensemblmetazoa:FBgn0264270(gene)|ensemblmetazoa:FBtr0331255(transcript)|ensemblmetazoa:FBtr0331262(transcript)|ensemblmetazoa:FBtr0331268(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007530"(sex determination)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0007548"(sex differentiation)|go:"GO:0007549"(dosage compensation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0009994"(oocyte differentiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018993"(somatic sex determination)|go:"GO:0030237"(female sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990399"(epithelium regeneration)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006546(Sex-lethal splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P19339|rcsb pdb:1B7F|rcsb pdb:1SXL|rcsb pdb:2SXL|rcsb pdb:3SXL|rcsb pdb:4QQB refseq:NP_511045.1|flybase:FBgn0003449|dip:DIP-23676N|ensemblmetazoa:FBgn0003449(gene)|ensemblmetazoa:FBtr0070748(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0007539"(primary sex determination, soma)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0019099"(female germ-line sex determination)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035614"(snRNA stem-loop binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097158"(pre-mRNA intronic pyrimidine-rich binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:2AYM|rcsb pdb:2B0G|rcsb pdb:2K3K|rcsb pdb:6F4G|rcsb pdb:6F4H|rcsb pdb:6F4I|rcsb pdb:6F4J|reactome:R-DME-72163 pubmed:8878676(see-also)|pubmed:9592147(see-also)|pubmed:8756662(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:OOLyyjkFbL8POQarQfx8Yhy8SV47227 rogid:f092+a2bHKIbT6VQoJMPYguAKGk7227 intact-crc:857A3E71FCC35952|rigid:CQYsKL/OV2nEWq3QOlf44Fxynrg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q26366 uniprotkb:A8JUV0 intact:EBI-162687|uniprotkb:Q9V6H9|ensemblmetazoa:FBpp0086898 intact:EBI-870796|uniprotkb:A8JUU9|uniprotkb:Q8MZI4|uniprotkb:Q95S83|uniprotkb:Q9VYF7|uniprotkb:O01940|ensemblmetazoa:FBpp0309425 psi-mi:vg_drome(display_long)|uniprotkb:vg(gene name)|psi-mi:vg(display_short)|uniprotkb:CG3830(orf name) psi-mi:sbno_drome(display_long)|uniprotkb:sno(gene name)|psi-mi:sno(display_short)|uniprotkb:CG44436(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874408 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523723.1|flybase:FBgn0003975|ensemblmetazoa:FBgn0003975(gene)|ensemblmetazoa:FBtr0087785(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007451"(dorsal/ventral lineage restriction, imaginal disc)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007473"(wing disc proximal/distal pattern formation)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016204"(determination of muscle attachment site)|go:"GO:0035220"(wing disc development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|interpro:IPR006627(Protein of unknown function TDU)|interpro:IPR011520(Vestigial/tondu)|rcsb pdb:6Y20 flybase:FBgn0265630|refseq:NP_001096967.1|refseq:NP_511144.2|ensemblmetazoa:FBgn0265630(gene)|ensemblmetazoa:FBtr0340489(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|interpro:IPR026741|interpro:IPR026937|interpro:IPR027417|interpro:IPR039187|go:"GO:0042461"(photoreceptor cell development) pubmed:11731237(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2016/03/30 rogid:uqFsfdTbzrZXahVD8igBvVK6t2o7227 rogid:FSIBiYLHZ5HcsMPM3a3yF/4wAjI7227 intact-crc:9D896A35F486B8CD|rigid:sl9tJSWs24PTKN+EJmhIPZiKiEY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20659 uniprotkb:Q24090 intact:EBI-591327|ensemblmetazoa:FBpp0082406|ensemblmetazoa:FBpp0082409|uniprotkb:Q27255|uniprotkb:Q27327|uniprotkb:Q8INF9|uniprotkb:Q960R2|uniprotkb:Q9VFL1|uniprotkb:A4V2V9|uniprotkb:A4V2W0|intact:EBI-3404288|intact:EBI-3417031|intact:EBI-9922180|intact:EBI-9933604 intact:EBI-151570|ensemblmetazoa:FBpp0078331 psi-mi:trx_drome(display_long)|uniprotkb:KMT2A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2A(gene name synonym)|uniprotkb:trx(gene name)|psi-mi:trx(display_short)|uniprotkb:CG8651(orf name)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:q24090_drome(display_long)|uniprotkb:Snr1(gene name)|psi-mi:Snr1(display_short)|uniprotkb:BAP45(gene name synonym)|uniprotkb:Dmel\CG1064(gene name synonym)|uniprotkb:SNR1(gene name synonym)|uniprotkb:Snr(gene name synonym)|uniprotkb:Snr-1(gene name synonym)|uniprotkb:"l(3)01319"(gene name synonym)|uniprotkb:snr(gene name synonym)|uniprotkb:snr-1(gene name synonym)|uniprotkb:snr1(gene name synonym)|uniprotkb:Dmel_CG1064(orf name)|uniprotkb:CG1064(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874412 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0003862(gene)|ensemblmetazoa:FBtr0082947(transcript)|ensemblmetazoa:FBtr0082950(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|reactome:R-DME-8936459|reactome:R-DME-8939236|refseq:NP_001014621.1|refseq:NP_476769.1|refseq:NP_476770.1|refseq:NP_599108.1|refseq:NP_599109.1|flybase:FBgn0003862 refseq:NP_730935.1|flybase:FBgn0011715|dip:DIP-17554N|ensemblmetazoa:FBgn0011715(gene)|ensemblmetazoa:FBtr0078682(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035060"(brahma complex)|go:"GO:0043044"|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070983"(dendrite guidance)|go:"GO:0070984"(SET domain binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|mint:Q24090|reactome:R-DME-3214858|reactome:R-DME-8939243 pubmed:12482982(see-also)|pubmed:9539705(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:LDT4/pLaHAuL/kuZMReRH9ZDrNk7227 rogid:fKg0O+kw3EfuBuHr8S9MQNxAugU7227 intact-crc:ED5399B57261F1EB|rigid:DU9yrizSjWW6WIuyzPyOQQYMYKY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24025 uniprotkb:P25723 intact:EBI-184947|uniprotkb:Q9VXS7|uniprotkb:B7FNI9|ensemblmetazoa:FBpp0073879|ensemblmetazoa:FBpp0304148|ensemblmetazoa:FBpp0309304 intact:EBI-115496|uniprotkb:Q9VC46|ensemblmetazoa:FBpp0084070 psi-mi:sog_drome(display_long)|uniprotkb:sog(gene name)|psi-mi:sog(display_short)|uniprotkb:CG9224(orf name)|uniprotkb:Short gastrulation protein(gene name synonym) psi-mi:tld_drome(display_long)|uniprotkb:tld(gene name)|psi-mi:tld(display_short)|uniprotkb:CG6868(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874416 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476736.1|flybase:FBgn0003463|refseq:NP_001259576.1|refseq:NP_001259578.1|dip:DIP-20760N|ensemblmetazoa:FBgn0003463(gene)|ensemblmetazoa:FBtr0074063(transcript)|ensemblmetazoa:FBtr0331760(transcript)|ensemblmetazoa:FBtr0340346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007313"(maternal specification of dorsal/ventral axis, oocyte, soma encoded)|go:"GO:0007378"(amnioserosa formation)|go:"GO:0008083"(growth factor activity)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0035271"(ring gland development)|go:"GO:0035592"(establishment of protein localization to extracellular region)|go:"GO:0036122"(BMP binding)|go:"GO:0038098"(sequestering of BMP from receptor via BMP binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0061328"(posterior Malpighian tubule development)|go:"GO:0110107"(regulation of imaginal disc-derived wing vein specification)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR010895(CHRD)|interpro:IPR016353(Chordin) refseq:NP_524487.2|flybase:FBgn0003719|ensemblmetazoa:FBgn0003719(gene)|ensemblmetazoa:FBtr0084691(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007313"(maternal specification of dorsal/ventral axis, oocyte, soma encoded)|go:"GO:0007378"(amnioserosa formation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0016485"(protein processing)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0045464"(R8 cell fate specification)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001506(Peptidase M12A, astacin)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR015446(Bone morphogenetic protein 1/tolloid-like protein)|interpro:IPR018097|interpro:IPR024079|interpro:IPR034036|interpro:IPR035914|reactome:R-DME-1650814|reactome:R-DME-2243919|interpro:IPR001881(EGF-like calcium-binding)|dip:DIP-22889N pubmed:11782317(see-also)|pubmed:9363950(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KC34gvwDW/5LKdgJ3UpuOFZiZUg7227 rogid:YdMM4yIwCvr3BEfcOk1c7jBHcw07227 intact-crc:370F31D702C51356|rigid:KkxXvTcrmxuiJ5mgBmQMTvE6RNc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P47825 uniprotkb:Q8IRM5 intact:EBI-277958|uniprotkb:P49845|uniprotkb:Q0E8E3|uniprotkb:Q1LZ31|uniprotkb:Q8T9E0|uniprotkb:Q9VUY7|ensemblmetazoa:FBpp0075205|ensemblmetazoa:FBpp0075206|ensemblmetazoa:FBpp0291125|ensemblmetazoa:FBpp0311865 intact:EBI-870824|ensemblmetazoa:FBpp0071316 psi-mi:taf4_drome(display_long)|uniprotkb:Transcription initiation factor TFIID 110 kDa subunit(gene name synonym)|uniprotkb:110 kDa TBP-associated factor(gene name synonym)|uniprotkb:Taf4(gene name)|psi-mi:Taf4(display_short)|uniprotkb:TAF110(gene name synonym)|uniprotkb:CG5444(orf name) psi-mi:q8irm5_drome(display_long)|uniprotkb:CG1343(orf name)|uniprotkb:D-Sp8(gene name synonym)|uniprotkb:D.Sp1(gene name synonym)|uniprotkb:Dmel\CG1343(gene name synonym)|uniprotkb:SP1(gene name synonym)|uniprotkb:dSp1(gene name synonym)|uniprotkb:sp1(gene name synonym)|uniprotkb:Dmel_CG1343(orf name)|uniprotkb:Sp1(gene name)|psi-mi:Sp1(display_short)|uniprotkb:D-Sp1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874420 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_788511.1|refseq:NP_996101.1|flybase:FBgn0010280|refseq:NP_001287077.1|refseq:NP_001163453.1|refseq:NP_524102.1|refseq:NP_730109.1|dip:DIP-237N|ensemblmetazoa:FBgn0010280(gene)|ensemblmetazoa:FBtr0075448(transcript)|ensemblmetazoa:FBtr0075449(transcript)|ensemblmetazoa:FBtr0301911(transcript)|ensemblmetazoa:FBtr0345951(transcript)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR007900(Transcription initiation factor TFIID component TAF4)|interpro:IPR009072(Histone-fold)|interpro:IPR037249|mint:P47825|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 refseq:NP_727360.1|flybase:FBgn0020378|ensemblmetazoa:FBgn0020378(gene)|ensemblmetazoa:FBtr0071381(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 pubmed:7923382(see-also)|pubmed:10220418(see-also)|pubmed:7678780(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KMwgcLywcp/YxxTLBjtmqXNPhdo7227 rogid:EgY/k/R6HwGAkeB33VFhwEE9Pa07227 intact-crc:28D7FFB88DDD5B79|rigid:U74WcpIT5VdUGXpZe5lydOM1RJ0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q94918 uniprotkb:Q01083 intact:EBI-869384|uniprotkb:Q9VRQ3|ensemblmetazoa:FBpp0076790 intact:EBI-91342|ensemblmetazoa:FBpp0080808|ensemblmetazoa:FBpp0080809|ensemblmetazoa:FBpp0080810|ensemblmetazoa:FBpp0080811|ensemblmetazoa:FBpp0100054|uniprotkb:Q8SXE0|uniprotkb:Q9VIT4 psi-mi:vein_drome(display_long)|uniprotkb:Epidermal growth factor-like protein(gene name synonym)|uniprotkb:Protein defective dorsal discs(gene name synonym)|uniprotkb:vn(gene name)|psi-mi:vn(display_short)|uniprotkb:ddd(gene name synonym)|uniprotkb:CG10491(orf name) psi-mi:spitz_drome(display_long)|uniprotkb:spi(gene name)|psi-mi:spi(display_short)|uniprotkb:CG10334(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874424 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523942.2|flybase:FBgn0003984|ensemblmetazoa:FBgn0003984(gene)|ensemblmetazoa:FBtr0077082(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007477"(notum development)|go:"GO:0007479"(leg disc proximal/distal pattern formation)|go:"GO:0007482"(haltere development)|go:"GO:0007494"(midgut development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0035310"(notum cell fate specification)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048513"(animal organ development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040180 go:"GO:0005789"(endoplasmic reticulum membrane)|ensemblmetazoa:FBgn0005672(gene)|ensemblmetazoa:FBtr0081267(transcript)|ensemblmetazoa:FBtr0081268(transcript)|ensemblmetazoa:FBtr0081269(transcript)|ensemblmetazoa:FBtr0081270(transcript)|ensemblmetazoa:FBtr0100597(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001713"(ectodermal cell fate determination)|go:"GO:0003015"(heart process)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001027281.1|refseq:NP_476909.2|refseq:NP_599118.2|refseq:NP_599119.2|refseq:NP_599120.2|flybase:FBgn0005672|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007421"(stomatogastric nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:3C9A|rcsb pdb:3CA7|rcsb pdb:3LTF|rcsb pdb:3LTG|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|dip:DIP-18037N pubmed:8824589(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NkLTC71WZ3fPunYHAmnJnWzjeNg7227 rogid:RO8D5JspHbtNUFx11JHFCoUuv0A7227 intact-crc:A81932F6B7C00868|rigid:1yv8RpULGpqc9NzMDz33j8gAiYk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08953 uniprotkb:P48607 intact:EBI-143610|uniprotkb:A4V3G7|uniprotkb:A8WHK7|uniprotkb:Q8MRF3|uniprotkb:Q9VBB8|ensemblmetazoa:FBpp0084431|ensemblmetazoa:FBpp0303188 intact:EBI-261915|uniprotkb:Q95SU5|uniprotkb:Q9VB84|ensemblmetazoa:FBpp0084507 psi-mi:toll_drome(display_long)|uniprotkb:Tl(gene name)|psi-mi:Tl(display_short)|uniprotkb:CG5490(orf name) psi-mi:spz_drome(display_long)|uniprotkb:spz(gene name)|psi-mi:spz(display_short)|uniprotkb:CG6134(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874428 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524518.1|refseq:NP_733166.1|flybase:FBgn0262473|dip:DIP-34358N|ensemblmetazoa:FBgn0262473(gene)|ensemblmetazoa:FBtr0085059(transcript)|ensemblmetazoa:FBtr0330155(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002229"(defense response to oomycetes)|go:"GO:0002347"(response to tumor cell)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007507"(heart development)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009597"(detection of virus)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0019955"(cytokine binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046790"(virion binding)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0070976"(TIR domain binding)|go:"GO:1902875"(regulation of embryonic pattern specification)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR026906|interpro:IPR032675|interpro:IPR035897|rcsb pdb:4ARN|rcsb pdb:4ARR|rcsb pdb:4BV4|rcsb pdb:4LXR|rcsb pdb:4LXS|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874 refseq:NP_524526.1|refseq:NP_733188.1|refseq:NP_733191.1|refseq:NP_733194.1|refseq:NP_733195.1|flybase:FBgn0003495|dip:DIP-23237N|ensemblmetazoa:FBgn0003495(gene)|ensemblmetazoa:FBtr0085137(transcript)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002347"(response to tumor cell)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0002807"(positive regulation of antimicrobial peptide biosynthetic process)|go:"GO:0005121"(Toll binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0006967"(positive regulation of antifungal peptide biosynthetic process)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0008083"(growth factor activity)|go:"GO:0008592"(regulation of Toll signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021556"(central nervous system formation)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061760"(antifungal innate immune response)|interpro:IPR029034|interpro:IPR032104|rcsb pdb:3E07|rcsb pdb:4BV4|rcsb pdb:4LXR|rcsb pdb:4LXS|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874 pubmed:10369678(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6nIbDMNS71rQ+CzvUkspyPjTd707227 rogid:odMgEmovtblzFvylNYMuYbP6ODE7227 intact-crc:5F4008C28F6BBE01|rigid:A1EoOm0bovmjRthsEneqMpwmWy4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P48607 uniprotkb:P48607 intact:EBI-261915|uniprotkb:Q95SU5|uniprotkb:Q9VB84|ensemblmetazoa:FBpp0084507 intact:EBI-261915|uniprotkb:Q95SU5|uniprotkb:Q9VB84|ensemblmetazoa:FBpp0084507 psi-mi:spz_drome(display_long)|uniprotkb:spz(gene name)|psi-mi:spz(display_short)|uniprotkb:CG6134(orf name) psi-mi:spz_drome(display_long)|uniprotkb:spz(gene name)|psi-mi:spz(display_short)|uniprotkb:CG6134(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874432 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524526.1|refseq:NP_733188.1|refseq:NP_733191.1|refseq:NP_733194.1|refseq:NP_733195.1|flybase:FBgn0003495|dip:DIP-23237N|ensemblmetazoa:FBgn0003495(gene)|ensemblmetazoa:FBtr0085137(transcript)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002347"(response to tumor cell)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0002807"(positive regulation of antimicrobial peptide biosynthetic process)|go:"GO:0005121"(Toll binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0006967"(positive regulation of antifungal peptide biosynthetic process)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0008083"(growth factor activity)|go:"GO:0008592"(regulation of Toll signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021556"(central nervous system formation)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061760"(antifungal innate immune response)|interpro:IPR029034|interpro:IPR032104|rcsb pdb:3E07|rcsb pdb:4BV4|rcsb pdb:4LXR|rcsb pdb:4LXS|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874 refseq:NP_524526.1|refseq:NP_733188.1|refseq:NP_733191.1|refseq:NP_733194.1|refseq:NP_733195.1|flybase:FBgn0003495|dip:DIP-23237N|ensemblmetazoa:FBgn0003495(gene)|ensemblmetazoa:FBtr0085137(transcript)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002347"(response to tumor cell)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0002807"(positive regulation of antimicrobial peptide biosynthetic process)|go:"GO:0005121"(Toll binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006965"(positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria)|go:"GO:0006967"(positive regulation of antifungal peptide biosynthetic process)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0008083"(growth factor activity)|go:"GO:0008592"(regulation of Toll signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021556"(central nervous system formation)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061760"(antifungal innate immune response)|interpro:IPR029034|interpro:IPR032104|rcsb pdb:3E07|rcsb pdb:4BV4|rcsb pdb:4LXR|rcsb pdb:4LXS|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874 pubmed:8124709(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:odMgEmovtblzFvylNYMuYbP6ODE7227 rogid:odMgEmovtblzFvylNYMuYbP6ODE7227 intact-crc:539A0277F10ADDB2|rigid:m0PurtUvi2CIybjMdbfFqyVFaeM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9VPQ6 uniprotkb:P52172 intact:EBI-110692|uniprotkb:Q6AWH0|uniprotkb:O18414|ensemblmetazoa:FBpp0077723 intact:EBI-668886|uniprotkb:Q6NMW1|uniprotkb:Q7K0H5|uniprotkb:Q8INC6|uniprotkb:Q94884|uniprotkb:Q9VF01|ensemblmetazoa:FBpp0082669 psi-mi:ush_drome(display_long)|uniprotkb:Protein U-shaped(gene name synonym)|uniprotkb:ush(gene name)|psi-mi:ush(display_short)|uniprotkb:CG2762(orf name) psi-mi:srp_drome(display_long)|uniprotkb:GATA-binding factor B(gene name synonym)|uniprotkb:Transcription factor GATA-B(gene name synonym)|uniprotkb:dGATA-B(gene name synonym)|uniprotkb:Protein serpent(gene name synonym)|uniprotkb:srp(gene name)|psi-mi:srp(display_short)|uniprotkb:ABF(gene name synonym)|uniprotkb:CG3992(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874436 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476780.1|flybase:FBgn0003963|ensemblmetazoa:FBgn0003963(gene)|ensemblmetazoa:FBtr0078063(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007507"(heart development)|go:"GO:0022416"(chaeta development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035169"(lymph gland plasmatocyte differentiation)|go:"GO:0035170"(lymph gland crystal cell differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045611"(negative regulation of hemocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046665"(amnioserosa maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048542"(lymph gland development)|go:"GO:0048749"(compound eye development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034731|interpro:IPR036236|interpro:IPR039746|rcsb pdb:1FU9|rcsb pdb:1FV5|rcsb pdb:1JN7|rcsb pdb:1Y0J|rcsb pdb:2L6Z|reactome:R-DME-8936459|reactome:R-DME-983231 refseq:NP_001027190.1|refseq:NP_732098.1|refseq:NP_732100.2|flybase:FBgn0003507|refseq:NP_001262618.1|ensemblmetazoa:FBgn0003507(gene)|ensemblmetazoa:FBtr0083215(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007492"(endoderm development)|go:"GO:0007494"(midgut development)|go:"GO:0007503"(fat body development)|go:"GO:0007516"(hemocyte development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042690"(negative regulation of crystal cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046665"(amnioserosa maintenance)|go:"GO:0048542"(lymph gland development)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|reactome:R-DME-5689880|reactome:R-DME-8939236|reactome:R-DME-9018519|reactome:R-DME-983231 pubmed:12374748(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:2CAaxvMNBtN3JUFnhUgsOAMFmYM7227 rogid:oi8aA2pnZhIBw3UzV+zfcd2B1KY7227 intact-crc:2568CE8A593E771A|rigid:+CNEH/JxJRBqpHVfupSBeNDIW9o false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O61543 uniprotkb:O15945 intact:EBI-870835 intact:EBI-172695|uniprotkb:O16167|uniprotkb:O44082|uniprotkb:Q24461|uniprotkb:Q9VHI2|intact:EBI-3417363|ensemblmetazoa:FBpp0081483|ensemblmetazoa:FBpp0307731 psi-mi:o61543_drome(display_long)|uniprotkb:ss(gene name)|psi-mi:ss(display_short)|uniprotkb:CG6993(orf name) psi-mi:arnt_drome(display_long)|uniprotkb:tgo(gene name)|psi-mi:tgo(display_short)|uniprotkb:ARNT(gene name synonym)|uniprotkb:HIF-1-beta(gene name synonym)|uniprotkb:CG11987(orf name)|uniprotkb:Protein tango(gene name synonym)|uniprotkb:Hypoxia-inducible factor 1-beta(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874440 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0003513|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007469"(antennal development)|go:"GO:0007613"(memory)|go:"GO:0008049"(male courtship behavior)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|interpro:IPR039091 refseq:NP_731308.1|flybase:FBgn0264075|refseq:NP_001262397.1|ensemblmetazoa:FBgn0264075(gene)|ensemblmetazoa:FBtr0082005(transcript)|ensemblmetazoa:FBtr0336755(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008347"(glial cell migration)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0017022"(myosin binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048736"(appendage development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-DME-1234158|reactome:R-DME-8937144 pubmed:10433921(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:9Nk2SPKMz5cDSno8cCBIPeooEGg7227 rogid:QfQjxuOMC66M3wNk0uC0IggqKbI7227 intact-crc:4E240AAD39BE43C8|rigid:QicHss2rwH3O0nb1NTdt0CcnKlE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42286 uniprotkb:Q9VRN6 intact:EBI-673051|uniprotkb:Q8MQL8|uniprotkb:Q94525|uniprotkb:Q9V894 intact:EBI-103537|ensemblmetazoa:FBpp0076831 psi-mi:thr_drome(display_long)|uniprotkb:thr(gene name)|psi-mi:thr(display_short)|uniprotkb:CG5785(orf name) psi-mi:q9vrn6_drome(display_long)|uniprotkb:Sse(gene name)|psi-mi:Sse(display_short)|uniprotkb:Dmel\CG10583(gene name synonym)|uniprotkb:SSE(gene name synonym)|uniprotkb:"l(3)13m-281"(gene name synonym)|uniprotkb:"l(3)SG14"(gene name synonym)|uniprotkb:sse(gene name synonym)|uniprotkb:Dmel_CG10583(orf name)|uniprotkb:CG10583(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874444 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_725731.2|flybase:FBgn0003701|refseq:NP_001286552.1|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005737"(cytoplasm)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007502"(digestive tract mesoderm development)|go:"GO:0008258"(head involution)|go:"GO:0008406"(gonad development)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation) refseq:NP_523935.1|flybase:FBgn0035627|ensemblmetazoa:FBgn0035627(gene)|ensemblmetazoa:FBtr0077125(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0016233"(telomere capping)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0140445"(chromosome, telomeric repeat region)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397 pubmed:14712087(see-also)|pubmed:11581162(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:a1Z9EE3khRRVl7Tre2muxb7S+NA7227 rogid:Etx9K4pTD3ff7gIOzH8u16bE/5o7227 intact-crc:FCE6917D90D28B8D|rigid:sQSaxMd+ewC4YlxHx2jvAGy97p8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P45594 uniprotkb:Q6NN85 intact:EBI-110774|uniprotkb:Q9W1C4|uniprotkb:C6SV25|ensemblmetazoa:FBpp0072097 intact:EBI-117889|uniprotkb:Q7KS05|uniprotkb:Q8IMU8|uniprotkb:Q9NKY1|uniprotkb:Q9VC04|ensemblmetazoa:FBpp0290828|intact:EBI-3420921 psi-mi:cadf_drome(display_long)|uniprotkb:Protein twinstar(gene name synonym)|uniprotkb:Protein D61(gene name synonym)|uniprotkb:tsr(gene name)|psi-mi:tsr(display_short)|uniprotkb:Cadf(gene name synonym)|uniprotkb:CG4254(orf name) psi-mi:ssh_drome(display_long)|uniprotkb:ssh(gene name)|psi-mi:ssh(display_short)|uniprotkb:CG6238(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874448 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477034.1|flybase:FBgn0011726|dip:DIP-20149N|ensemblmetazoa:FBgn0011726(gene)|ensemblmetazoa:FBtr0072188(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007409"(axonogenesis)|go:"GO:0008585"(female gonad development)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016319"(mushroom body development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0048749"(compound eye development)|go:"GO:0048870"(cell motility)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051299"(centrosome separation)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|rcsb pdb:2MV2 interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR043587|interpro:IPR043588|ensemblmetazoa:FBgn0029157(gene)|ensemblmetazoa:FBtr0301613(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007097"(nuclear migration)|go:"GO:0007409"(axonogenesis)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0016319"(mushroom body development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0045177"(apical part of cell)|go:"GO:0048749"(compound eye development)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR014876(DEK C terminal)|refseq:NP_001163716.1|refseq:NP_001163717.1|refseq:NP_524492.2|refseq:NP_733063.1|flybase:FBgn0029157 pubmed:11832213(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:khdE8vWqs/u/7AeaXb5MlajmjjM7227 rogid:OtNooluKc3xqdcJaFUs/PbDD6DE7227 intact-crc:6454CBC69E96C430|rigid:6QyXQ53NmkJQ+ne1IYHFj1Mm5F4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q08605 uniprotkb:Q05344 intact:EBI-300317|uniprotkb:Q08083|uniprotkb:Q7JN57|uniprotkb:Q8MYL3|uniprotkb:Q8T387|uniprotkb:Q9V3X7|uniprotkb:Q9VUH2|uniprotkb:O18349|uniprotkb:O18350|uniprotkb:O18526 intact:EBI-170040|uniprotkb:Q86NM5|uniprotkb:Q9W1J4|ensemblmetazoa:FBpp0072151 psi-mi:gaga_drome(display_long)|uniprotkb:Trl(gene name)|psi-mi:Trl(display_short)|uniprotkb:GAGA(gene name synonym)|uniprotkb:TFGAGA(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:GAGA factor(gene name synonym)|uniprotkb:Adh transcription factor 2(gene name synonym)|uniprotkb:Neural conserved at 70F(gene name synonym)|uniprotkb:Adf-2(gene name synonym)|uniprotkb:Nc70F(gene name synonym)|uniprotkb:CG33261(orf name) psi-mi:ssrp1_drome(display_long)|uniprotkb:Ssrp(gene name)|psi-mi:Ssrp(display_short)|uniprotkb:CF5(gene name synonym)|uniprotkb:SSRP1(gene name synonym)|uniprotkb:CG4817(orf name)|uniprotkb:Facilitates chromatin transcription complex subunit Ssrp1(gene name synonym)|uniprotkb:Recombination signal sequence recognition protein(gene name synonym)|uniprotkb:Single-strand recognition protein(gene name synonym)|uniprotkb:dSSRP1(gene name synonym)|uniprotkb:Chorion-factor 5(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874452 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000280"(nuclear division)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007549"(dosage compensation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0034728"(nucleosome organization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051301"(cell division)|go:"GO:1901409"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:1990000"(amyloid fibril formation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR015318(Zinc finger, GAGAG binding factor)|rcsb pdb:1YUI|rcsb pdb:1YUJ|go:"GO:0035075"(response to ecdysone)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043044"|refseq:NP_001034014.1|refseq:NP_996077.1|refseq:NP_996078.1|refseq:NP_996079.1|refseq:NP_996080.1|refseq:NP_996081.1|refseq:NP_996082.1|flybase:FBgn0013263 refseq:NP_523830.2|flybase:FBgn0010278|ensemblmetazoa:FBgn0010278(gene)|ensemblmetazoa:FBtr0072242(transcript)|go:"GO:0001672"(regulation of chromatin assembly or disassembly)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043621"(protein self-association)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR036910|interpro:IPR038167|rcsb pdb:1WXL|reactome:R-DME-112382|reactome:R-DME-674695|reactome:R-DME-6796648|reactome:R-DME-6804756|reactome:R-DME-75955|go:"GO:0035101"(FACT complex) pubmed:12815073(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:s2lpiYJCLr9x3aKiQRvlG3gE9nk7227 rogid:rCvjDSDpdeHyFCE+Sg8vRqu4z/Q7227 intact-crc:6F408D86D96E9405|rigid:zuRE8EjhmSQR/r3c2p0gTS0J3a0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10090 uniprotkb:P45843 intact:EBI-93778|uniprotkb:Q9V3A2|uniprotkb:Q9XY33|ensemblmetazoa:FBpp0070468 intact:EBI-162620|uniprotkb:Q6NP00|uniprotkb:Q6NR69|uniprotkb:Q9VV67|ensemblmetazoa:FBpp0075149 psi-mi:white_drome(display_long)|uniprotkb:w(gene name)|psi-mi:w(display_short)|uniprotkb:CG2759(orf name) psi-mi:scrt_drome(display_long)|uniprotkb:st(gene name)|psi-mi:st(display_short)|uniprotkb:CG4314(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874456 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476787.1|flybase:FBgn0003996|ensemblmetazoa:FBgn0003996(gene)|ensemblmetazoa:FBtr0070490(transcript)|go:"GO:0005275"(amine transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006727"(ommochrome biosynthetic process)|go:"GO:0006856"(eye pigment precursor transport)|go:"GO:0007613"(memory)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008558"(ABC-type guanine transporter activity)|go:"GO:0015196"(L-tryptophan transmembrane transporter activity)|go:"GO:0015842"(aminergic neurotransmitter loading into synaptic vesicle)|go:"GO:0031409"(pigment binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042332"(gravitaxis)|go:"GO:0042401"(cellular biogenic amine biosynthetic process)|go:"GO:0042441"(eye pigment metabolic process)|go:"GO:0048072"(compound eye pigmentation)|go:"GO:0048770"(pigment granule)|go:"GO:0051615"(histamine uptake)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070731"(cGMP transport)|go:"GO:0090740"(integral component of pigment granule membrane)|go:"GO:0098793"(presynapse)|go:"GO:1905948"(ABC-type 3',5'-cyclic GMP transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005284(Pigment precursor permease)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR043926|dip:DIP-388N refseq:NP_524108.1|flybase:FBgn0003515|ensemblmetazoa:FBgn0003515(gene)|ensemblmetazoa:FBtr0075391(transcript)|go:"GO:0005275"(amine transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006727"(ommochrome biosynthetic process)|go:"GO:0006856"(eye pigment precursor transport)|go:"GO:0015842"(aminergic neurotransmitter loading into synaptic vesicle)|go:"GO:0031409"(pigment binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0090740"(integral component of pigment granule membrane)|go:"GO:0098793"(presynapse)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005284(Pigment precursor permease)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR043926|reactome:R-DME-1369062|reactome:R-DME-189451|reactome:R-DME-189483|reactome:R-DME-917937 pubmed:11294610(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:nE6hAxiYy5nq99VxDZoDohuWpqc7227 rogid:r3qylTQZLGgN+a1jzk42baFD/VI7227 intact-crc:C61D39EA2F13C51A|rigid:Vg9GiVQcOZEJ4dLmKsJjYNqRPq4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24151 uniprotkb:Q7KNF5 intact:EBI-254777|uniprotkb:Q0KI43|uniprotkb:Q24181|uniprotkb:Q59DV7|uniprotkb:Q5BIB0|uniprotkb:Q8IN54|uniprotkb:Q8SX55|uniprotkb:Q9VDL8|ensemblmetazoa:FBpp0088489|ensemblmetazoa:FBpp0306653 intact:EBI-870871|ensemblmetazoa:FBpp0087659 psi-mi:stat_drome(display_long)|uniprotkb:Stat92E(gene name)|psi-mi:Stat92E(display_short)|uniprotkb:MARE(gene name synonym)|uniprotkb:Stat(gene name synonym)|uniprotkb:mrL(gene name synonym)|uniprotkb:CG4257(orf name)|uniprotkb:Protein marelle(gene name synonym) psi-mi:q7knf5_drome(display_long)|uniprotkb:CG8068(orf name)|uniprotkb:"Su(var)2-10"(gene name)|psi-mi:"Su(var)2-10"(display_short)|uniprotkb:zimp(gene name synonym)|uniprotkb:Dmel_CG8068(orf name)|uniprotkb:CLOT2057(gene name synonym)|uniprotkb:DPIAS(gene name synonym)|uniprotkb:DmPias(gene name synonym)|uniprotkb:Dmel\CG8068(gene name synonym)|uniprotkb:Dpias(gene name synonym)|uniprotkb:PIAS(gene name synonym)|uniprotkb:"SU(VAR)2-10"(gene name synonym)|uniprotkb:"Su(Var)2-10"(gene name synonym)|uniprotkb:"Su(var)-10"(gene name synonym)|uniprotkb:"Su-var(2)10"(gene name synonym)|uniprotkb:"Suvar(2)10"(gene name synonym)|uniprotkb:ZIMP(gene name synonym)|uniprotkb:ZimpA(gene name synonym)|uniprotkb:ZimpB(gene name synonym)|uniprotkb:dPIAS(gene name synonym)|uniprotkb:dpias(gene name synonym)|uniprotkb:i184(gene name synonym)|uniprotkb:"l(2)03697"(gene name synonym)|uniprotkb:pias(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874460 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014643.1|refseq:NP_732516.2|refseq:NP_732517.2|refseq:NP_996242.1|refseq:NP_996243.1|flybase:FBgn0016917|refseq:NP_001262757.1|refseq:NP_001262762.1|dip:DIP-29510N|ensemblmetazoa:FBgn0016917(gene)|ensemblmetazoa:FBtr0089486(transcript)|ensemblmetazoa:FBtr0334586(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007379"(segment specification)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0007538"(primary sex determination)|go:"GO:0007616"(long-term memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008348"(negative regulation of antimicrobial humoral response)|go:"GO:0017145"(stem cell division)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042393"(histone binding)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR036535|interpro:IPR036860|reactome:R-DME-1059683|reactome:R-DME-1251985|reactome:R-DME-1433557|reactome:R-DME-186763|reactome:R-DME-209228|reactome:R-DME-209394|reactome:R-DME-209405|reactome:R-DME-210671|reactome:R-DME-210688|reactome:R-DME-210693|reactome:R-DME-3249367|reactome:R-DME-6783783|reactome:R-DME-6785807|reactome:R-DME-877300|reactome:R-DME-877312|reactome:R-DME-8854691|reactome:R-DME-8983432|reactome:R-DME-8984722|reactome:R-DME-8985947|reactome:R-DME-9008059|reactome:R-DME-9020591|reactome:R-DME-9020933|reactome:R-DME-9020956|reactome:R-DME-909733 flybase:FBgn0003612|refseq:NP_523664.1|ensemblmetazoa:FBgn0003612(gene)|ensemblmetazoa:FBtr0088578(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048749"(compound eye development)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051276"(chromosome organization)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|reactome:R-DME-210671 pubmed:11504941(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:sAAgBR+DCg0o/jzk+KFV/ZH6aMU7227 rogid:RXbxTkd+58q0LfXyJ58++oZdIrY7227 intact-crc:F3F9F7845965D24B|rigid:bgFnQAgn+7zsryfP99udau/2MI0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8IR23 uniprotkb:O44783 intact:EBI-868068|ensemblmetazoa:FBpp0073945|ensemblmetazoa:FBpp0073946|ensemblmetazoa:FBpp0089147|ensemblmetazoa:FBpp0089148|ensemblmetazoa:FBpp0309361|ensemblmetazoa:FBpp0309362 intact:EBI-132097|uniprotkb:A4V1F3|uniprotkb:Q6AWR4|uniprotkb:Q9VZP7|ensemblmetazoa:FBpp0073004|ensemblmetazoa:FBpp0073005 psi-mi:q8ir23_drome(display_long)|uniprotkb:D-RasGAP(gene name synonym)|uniprotkb:Dmel\CG9209(gene name synonym)|uniprotkb:FBpp0073946(gene name synonym)|uniprotkb:RAS-GAP(gene name synonym)|uniprotkb:RasGAP(gene name synonym)|uniprotkb:Vap(gene name synonym)|uniprotkb:p120RasGAP(gene name synonym)|uniprotkb:rasGap(gene name synonym)|uniprotkb:vap(gene name)|psi-mi:vap(display_short)|uniprotkb:RasGap(gene name synonym)|uniprotkb:Dmel_CG9209(orf name)|uniprotkb:p120 RasGAP(gene name synonym)|uniprotkb:vap-RA(gene name synonym)|uniprotkb:CG9209(orf name) psi-mi:spy_drome(display_long)|uniprotkb:sty(gene name)|psi-mi:sty(display_short)|uniprotkb:CG1921(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874464 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523361.1|refseq:NP_727925.1|refseq:NP_727926.2|refseq:NP_996482.1|flybase:FBgn0003969|refseq:NP_001285314.1|refseq:NP_001285315.1|ensemblmetazoa:FBgn0003969(gene)|ensemblmetazoa:FBtr0074140(transcript)|ensemblmetazoa:FBtr0074141(transcript)|ensemblmetazoa:FBtr0074142(transcript)|ensemblmetazoa:FBtr0074143(transcript)|ensemblmetazoa:FBtr0340415(transcript)|ensemblmetazoa:FBtr0340416(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005122"(torso binding)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016319"(mushroom body development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0120177"(negative regulation of torso signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023152|interpro:IPR028554|interpro:IPR035652|interpro:IPR035841|interpro:IPR035842|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|interpro:IPR039360|mint:Q8IR23|reactome:R-DME-186763|reactome:R-DME-3928662|reactome:R-DME-5218921|reactome:R-DME-8849471 refseq:NP_523902.2|refseq:NP_728881.1|flybase:FBgn0014388|ensemblmetazoa:FBgn0014388(gene)|ensemblmetazoa:FBtr0073145(transcript)|ensemblmetazoa:FBtr0073146(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007424"(open tracheal system development)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0021782"(glial cell development)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045314"(regulation of compound eye photoreceptor development)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0055001"(muscle cell development)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0110109"(negative regulation of imaginal disc-derived wing vein specification)|interpro:IPR007875(Sprouty)|reactome:R-DME-1295596|reactome:R-DME-182971|go:"GO:0120177"(negative regulation of torso signaling pathway)|dip:DIP-17914N pubmed:10089881(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Qc4rc5oeH6PrmaZ75RzhCWjUYgU7227 rogid:Epk95p/MSvHN+VVqzKqaTdmoO6g7227 intact-crc:DFBABCE192CB6E95|rigid:BAdR0QfDsideHvJcAzb5Xjs18B8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P05205 uniprotkb:A1Z9S5 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 intact:EBI-870882|ensemblmetazoa:FBpp0086631 psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:a1z9s5_drome(display_long)|uniprotkb:CG12864(orf name)|uniprotkb:"Su(var)2-HP2"(gene name)|psi-mi:"Su(var)2-HP2"(display_short)|uniprotkb:Dmel_CG12864(orf name)|uniprotkb:"Su(var)2-HP2-RB"(gene name synonym)|uniprotkb:Dmel\CG12864(gene name synonym)|uniprotkb:HP2(gene name synonym)|uniprotkb:Hp2(gene name synonym)|uniprotkb:"SU(VAR)2-HP2"(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874468 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA refseq:NP_788354.1|flybase:FBgn0026427|ensemblmetazoa:FBgn0026427(gene)|ensemblmetazoa:FBtr0087502(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005700"(polytene chromosome)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0051276"(chromosome organization) pubmed:12376620(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 rogid:+Cwd3+ofF2ylJug/2ekDVnRbf9g7227 intact-crc:9CFDA7377A3A8451|rigid:4js+q/4yQ8uw7mWbk4AEJa+Jq5Q false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20193 uniprotkb:P20193 intact:EBI-108673|uniprotkb:Q9VFX7|ensemblmetazoa:FBpp0082204 intact:EBI-108673|uniprotkb:Q9VFX7|ensemblmetazoa:FBpp0082204 psi-mi:suv37_drome(display_long)|uniprotkb:"Su(var)3-7"(gene name)|psi-mi:"Su(var)3-7"(display_short)|uniprotkb:CG8599(orf name)|uniprotkb:"Suvar(3)7"(gene name synonym) psi-mi:suv37_drome(display_long)|uniprotkb:"Su(var)3-7"(gene name)|psi-mi:"Su(var)3-7"(display_short)|uniprotkb:CG8599(orf name)|uniprotkb:"Suvar(3)7"(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874472 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524342.3|flybase:FBgn0003598|ensemblmetazoa:FBgn0003598(gene)|ensemblmetazoa:FBtr0082736(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004367"(glycerol-3-phosphate dehydrogenase [NAD+] activity)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006116"(NADH oxidation)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|interpro:IPR004210(BESS motif) refseq:NP_524342.3|flybase:FBgn0003598|ensemblmetazoa:FBgn0003598(gene)|ensemblmetazoa:FBtr0082736(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004367"(glycerol-3-phosphate dehydrogenase [NAD+] activity)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006116"(NADH oxidation)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|interpro:IPR004210(BESS motif) pubmed:12163401(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:RoAuo6NH8jq8dliHvYA1PY/HYtI7227 rogid:RoAuo6NH8jq8dliHvYA1PY/HYtI7227 intact-crc:272772B7EA5516F7|rigid:ltdXHxIprfHAQKgQJz55mVZJdIA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P05205 uniprotkb:P20193 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 intact:EBI-108673|uniprotkb:Q9VFX7|ensemblmetazoa:FBpp0082204 psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:suv37_drome(display_long)|uniprotkb:"Su(var)3-7"(gene name)|psi-mi:"Su(var)3-7"(display_short)|uniprotkb:CG8599(orf name)|uniprotkb:"Suvar(3)7"(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874476 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA refseq:NP_524342.3|flybase:FBgn0003598|ensemblmetazoa:FBgn0003598(gene)|ensemblmetazoa:FBtr0082736(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004367"(glycerol-3-phosphate dehydrogenase [NAD+] activity)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006116"(NADH oxidation)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|interpro:IPR004210(BESS motif) pubmed:11069770(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 rogid:RoAuo6NH8jq8dliHvYA1PY/HYtI7227 intact-crc:BBEC66C8A640C63B|rigid:f9u0YdN3LcYTjNbBd10CS1dBtXs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24562 uniprotkb:P19339 intact:EBI-165226|uniprotkb:Q9VXH2|ensemblmetazoa:FBpp0074013|ensemblmetazoa:FBpp0298007 intact:EBI-199576|uniprotkb:P19340|uniprotkb:Q0KHV2|uniprotkb:Q26466|uniprotkb:Q2MGN7|uniprotkb:Q2MGN8|uniprotkb:Q2MGN9|uniprotkb:Q2MGP1|uniprotkb:Q7KVU6|uniprotkb:Q7YZ92|uniprotkb:Q8IRQ1|uniprotkb:Q99141|uniprotkb:Q9TYF5|uniprotkb:Q9W3S6|uniprotkb:A4V435|uniprotkb:A4V437|uniprotkb:A4V434|uniprotkb:A4V436|uniprotkb:C9QP40|uniprotkb:D0IQK2|uniprotkb:D3PFI6|uniprotkb:E1JJI8|uniprotkb:E1JJI9|uniprotkb:E1JJJ0|uniprotkb:E1JJJ2|uniprotkb:E1JJJ3|ensemblmetazoa:FBpp0303697|ensemblmetazoa:FBpp0303704|ensemblmetazoa:FBpp0303710 psi-mi:u2af2_drome(display_long)|uniprotkb:U2af50(gene name)|psi-mi:U2af50(display_short)|uniprotkb:CG9998(orf name)|uniprotkb:U2 auxiliary factor 50 kDa subunit(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor large subunit(gene name synonym) psi-mi:sxl_drome(display_long)|uniprotkb:Sxl(gene name)|psi-mi:Sxl(display_short)|uniprotkb:Sx1(gene name synonym)|uniprotkb:CG43770(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874480 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245710.1|refseq:NP_476891.1|flybase:FBgn0005411|ensemblmetazoa:FBgn0005411(gene)|ensemblmetazoa:FBtr0074234(transcript)|ensemblmetazoa:FBtr0307178(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051168"(nuclear export)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006529(U2 snRNP auxilliary factor, large subunit, splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-DME-159236|reactome:R-DME-72163|reactome:R-DME-72187|reactome:R-DME-73856|dip:DIP-23323N refseq:NP_727161.3|refseq:NP_001027062.1|refseq:NP_001027063.1|refseq:NP_001027064.1|refseq:NP_001027065.1|refseq:NP_001027066.1|refseq:NP_001162686.1|refseq:NP_001162687.1|refseq:NP_001162688.1|refseq:NP_001162689.1|refseq:NP_001162690.1|refseq:NP_524791.3|refseq:NP_727160.2|refseq:NP_727162.2|refseq:NP_727163.2|refseq:NP_727164.2|refseq:NP_727165.2|refseq:NP_727166.2|refseq:NP_727167.2|refseq:NP_727168.1|refseq:NP_001259305.1|refseq:NP_001259306.1|flybase:FBgn0264270|dip:DIP-44607N|ensemblmetazoa:FBgn0264270(gene)|ensemblmetazoa:FBtr0331255(transcript)|ensemblmetazoa:FBtr0331262(transcript)|ensemblmetazoa:FBtr0331268(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007530"(sex determination)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0007548"(sex differentiation)|go:"GO:0007549"(dosage compensation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0009994"(oocyte differentiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018993"(somatic sex determination)|go:"GO:0030237"(female sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990399"(epithelium regeneration)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006546(Sex-lethal splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P19339|rcsb pdb:1B7F|rcsb pdb:1SXL|rcsb pdb:2SXL|rcsb pdb:3SXL|rcsb pdb:4QQB pubmed:12490553(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xSz9Dzo5kqYOSLEX/KbA5+ciURs7227 rogid:OOLyyjkFbL8POQarQfx8Yhy8SV47227 intact-crc:E4B850304697A5F7|rigid:tRnvL/EWnLAXz+Ss3fT6c+MxyRQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q94535 uniprotkb:P19339 intact:EBI-121011|uniprotkb:Q9VPN4|ensemblmetazoa:FBpp0077792|ensemblmetazoa:FBpp0305600 intact:EBI-199576|uniprotkb:P19340|uniprotkb:Q0KHV2|uniprotkb:Q26466|uniprotkb:Q2MGN7|uniprotkb:Q2MGN8|uniprotkb:Q2MGN9|uniprotkb:Q2MGP1|uniprotkb:Q7KVU6|uniprotkb:Q7YZ92|uniprotkb:Q8IRQ1|uniprotkb:Q99141|uniprotkb:Q9TYF5|uniprotkb:Q9W3S6|uniprotkb:A4V435|uniprotkb:A4V437|uniprotkb:A4V434|uniprotkb:A4V436|uniprotkb:C9QP40|uniprotkb:D0IQK2|uniprotkb:D3PFI6|uniprotkb:E1JJI8|uniprotkb:E1JJI9|uniprotkb:E1JJJ0|uniprotkb:E1JJJ2|uniprotkb:E1JJJ3|ensemblmetazoa:FBpp0303697|ensemblmetazoa:FBpp0303704|ensemblmetazoa:FBpp0303710 psi-mi:u2af1_drome(display_long)|uniprotkb:U2af38(gene name)|psi-mi:U2af38(display_short)|uniprotkb:CG3582(orf name)|uniprotkb:U2 auxiliary factor 38 kDa subunit(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor small subunit(gene name synonym) psi-mi:sxl_drome(display_long)|uniprotkb:Sxl(gene name)|psi-mi:Sxl(display_short)|uniprotkb:Sx1(gene name synonym)|uniprotkb:CG43770(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874484 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477208.1|flybase:FBgn0017457|ensemblmetazoa:FBgn0017457(gene)|ensemblmetazoa:FBtr0078133(transcript)|ensemblmetazoa:FBtr0333408(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR009145(U2 auxiliary factor small subunit)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-DME-159236|reactome:R-DME-72163|reactome:R-DME-72187|reactome:R-DME-73856|refseq:NP_001259814.1|dip:DIP-23299N refseq:NP_727161.3|refseq:NP_001027062.1|refseq:NP_001027063.1|refseq:NP_001027064.1|refseq:NP_001027065.1|refseq:NP_001027066.1|refseq:NP_001162686.1|refseq:NP_001162687.1|refseq:NP_001162688.1|refseq:NP_001162689.1|refseq:NP_001162690.1|refseq:NP_524791.3|refseq:NP_727160.2|refseq:NP_727162.2|refseq:NP_727163.2|refseq:NP_727164.2|refseq:NP_727165.2|refseq:NP_727166.2|refseq:NP_727167.2|refseq:NP_727168.1|refseq:NP_001259305.1|refseq:NP_001259306.1|flybase:FBgn0264270|dip:DIP-44607N|ensemblmetazoa:FBgn0264270(gene)|ensemblmetazoa:FBtr0331255(transcript)|ensemblmetazoa:FBtr0331262(transcript)|ensemblmetazoa:FBtr0331268(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007530"(sex determination)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0007548"(sex differentiation)|go:"GO:0007549"(dosage compensation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0009994"(oocyte differentiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018993"(somatic sex determination)|go:"GO:0030237"(female sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990399"(epithelium regeneration)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006546(Sex-lethal splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P19339|rcsb pdb:1B7F|rcsb pdb:1SXL|rcsb pdb:2SXL|rcsb pdb:3SXL|rcsb pdb:4QQB pubmed:12490553(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+bqsp/StCySByYEpSvoorP2hoRI7227 rogid:OOLyyjkFbL8POQarQfx8Yhy8SV47227 intact-crc:A42B2B65EA0F5227|rigid:/7Ti3QB8XGlYV8jTiIlDVaXcGb0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P19339 uniprotkb:P19339 intact:EBI-199576|uniprotkb:P19340|uniprotkb:Q0KHV2|uniprotkb:Q26466|uniprotkb:Q2MGN7|uniprotkb:Q2MGN8|uniprotkb:Q2MGN9|uniprotkb:Q2MGP1|uniprotkb:Q7KVU6|uniprotkb:Q7YZ92|uniprotkb:Q8IRQ1|uniprotkb:Q99141|uniprotkb:Q9TYF5|uniprotkb:Q9W3S6|uniprotkb:A4V435|uniprotkb:A4V437|uniprotkb:A4V434|uniprotkb:A4V436|uniprotkb:C9QP40|uniprotkb:D0IQK2|uniprotkb:D3PFI6|uniprotkb:E1JJI8|uniprotkb:E1JJI9|uniprotkb:E1JJJ0|uniprotkb:E1JJJ2|uniprotkb:E1JJJ3|ensemblmetazoa:FBpp0303697|ensemblmetazoa:FBpp0303704|ensemblmetazoa:FBpp0303710 intact:EBI-199576|uniprotkb:P19340|uniprotkb:Q0KHV2|uniprotkb:Q26466|uniprotkb:Q2MGN7|uniprotkb:Q2MGN8|uniprotkb:Q2MGN9|uniprotkb:Q2MGP1|uniprotkb:Q7KVU6|uniprotkb:Q7YZ92|uniprotkb:Q8IRQ1|uniprotkb:Q99141|uniprotkb:Q9TYF5|uniprotkb:Q9W3S6|uniprotkb:A4V435|uniprotkb:A4V437|uniprotkb:A4V434|uniprotkb:A4V436|uniprotkb:C9QP40|uniprotkb:D0IQK2|uniprotkb:D3PFI6|uniprotkb:E1JJI8|uniprotkb:E1JJI9|uniprotkb:E1JJJ0|uniprotkb:E1JJJ2|uniprotkb:E1JJJ3|ensemblmetazoa:FBpp0303697|ensemblmetazoa:FBpp0303704|ensemblmetazoa:FBpp0303710 psi-mi:sxl_drome(display_long)|uniprotkb:Sxl(gene name)|psi-mi:Sxl(display_short)|uniprotkb:Sx1(gene name synonym)|uniprotkb:CG43770(orf name) psi-mi:sxl_drome(display_long)|uniprotkb:Sxl(gene name)|psi-mi:Sxl(display_short)|uniprotkb:Sx1(gene name synonym)|uniprotkb:CG43770(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874488 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_727161.3|refseq:NP_001027062.1|refseq:NP_001027063.1|refseq:NP_001027064.1|refseq:NP_001027065.1|refseq:NP_001027066.1|refseq:NP_001162686.1|refseq:NP_001162687.1|refseq:NP_001162688.1|refseq:NP_001162689.1|refseq:NP_001162690.1|refseq:NP_524791.3|refseq:NP_727160.2|refseq:NP_727162.2|refseq:NP_727163.2|refseq:NP_727164.2|refseq:NP_727165.2|refseq:NP_727166.2|refseq:NP_727167.2|refseq:NP_727168.1|refseq:NP_001259305.1|refseq:NP_001259306.1|flybase:FBgn0264270|dip:DIP-44607N|ensemblmetazoa:FBgn0264270(gene)|ensemblmetazoa:FBtr0331255(transcript)|ensemblmetazoa:FBtr0331262(transcript)|ensemblmetazoa:FBtr0331268(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007530"(sex determination)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0007548"(sex differentiation)|go:"GO:0007549"(dosage compensation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0009994"(oocyte differentiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018993"(somatic sex determination)|go:"GO:0030237"(female sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990399"(epithelium regeneration)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006546(Sex-lethal splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P19339|rcsb pdb:1B7F|rcsb pdb:1SXL|rcsb pdb:2SXL|rcsb pdb:3SXL|rcsb pdb:4QQB refseq:NP_727161.3|refseq:NP_001027062.1|refseq:NP_001027063.1|refseq:NP_001027064.1|refseq:NP_001027065.1|refseq:NP_001027066.1|refseq:NP_001162686.1|refseq:NP_001162687.1|refseq:NP_001162688.1|refseq:NP_001162689.1|refseq:NP_001162690.1|refseq:NP_524791.3|refseq:NP_727160.2|refseq:NP_727162.2|refseq:NP_727163.2|refseq:NP_727164.2|refseq:NP_727165.2|refseq:NP_727166.2|refseq:NP_727167.2|refseq:NP_727168.1|refseq:NP_001259305.1|refseq:NP_001259306.1|flybase:FBgn0264270|dip:DIP-44607N|ensemblmetazoa:FBgn0264270(gene)|ensemblmetazoa:FBtr0331255(transcript)|ensemblmetazoa:FBtr0331262(transcript)|ensemblmetazoa:FBtr0331268(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007530"(sex determination)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0007548"(sex differentiation)|go:"GO:0007549"(dosage compensation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0009994"(oocyte differentiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018993"(somatic sex determination)|go:"GO:0030237"(female sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990399"(epithelium regeneration)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006546(Sex-lethal splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P19339|rcsb pdb:1B7F|rcsb pdb:1SXL|rcsb pdb:2SXL|rcsb pdb:3SXL|rcsb pdb:4QQB pubmed:9592147(see-also)|pubmed:8982872(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:OOLyyjkFbL8POQarQfx8Yhy8SV47227 rogid:OOLyyjkFbL8POQarQfx8Yhy8SV47227 intact-crc:0DBB2BD9F48A1A5A|rigid:67FHobal7IRZhj8iPZiVBbI8WB4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24547 uniprotkb:P18489 intact:EBI-135062|intact:EBI-1628359|uniprotkb:Q9TX14|uniprotkb:Q9VCD7|ensemblmetazoa:FBpp0083973|ensemblmetazoa:FBpp0352246 intact:EBI-497912|uniprotkb:Q8MKX1|uniprotkb:Q9V5I6|uniprotkb:Q3HKB4|uniprotkb:B7YZD5|uniprotkb:B7YZD6|ensemblmetazoa:FBpp0271782 psi-mi:stx1a_drome(display_long)|uniprotkb:Syx1A(gene name)|psi-mi:Syx1A(display_short)|uniprotkb:syx-1A(gene name synonym)|uniprotkb:CG31136(orf name)|uniprotkb:dSynt1(gene name synonym) psi-mi:syb_drome(display_long)|uniprotkb:Syb(gene name)|psi-mi:Syb(display_short)|uniprotkb:CG12210(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874492 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524475.1|flybase:FBgn0013343|refseq:NP_001303545.1|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-449836|reactome:R-DME-888590|reactome:R-DME-9609523|ensemblmetazoa:FBgn0013343(gene)|go:"GO:0007482"(haltere development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|ensemblmetazoa:FBtr0084588(transcript)|ensemblmetazoa:FBtr0392904(transcript)|go:"GO:0000149"(SNARE binding)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|reactome:R-DME-181429|reactome:R-DME-181430|go:"GO:0007349"(cellularization)|dip:DIP-19389N refseq:NP_001286278.1|refseq:NP_001137633.1|refseq:NP_001137634.1|refseq:NP_523680.1|refseq:NP_724906.1|flybase:FBgn0003660|ensemblmetazoa:FBgn0003660(gene)|ensemblmetazoa:FBtr0273274(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0043005"(neuron projection)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|reactome:R-DME-181429|reactome:R-DME-181430|reactome:R-DME-210500|reactome:R-DME-212676|reactome:R-DME-264642|reactome:R-DME-432720|reactome:R-DME-432722|reactome:R-DME-449836|reactome:R-DME-6798695|reactome:R-DME-6811440|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-888590|reactome:R-DME-8980692|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-9013405|reactome:R-DME-9013406|reactome:R-DME-9013407|reactome:R-DME-9035034|reactome:R-DME-9609523 pubmed:9728921(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:xlJYHz+B+bylWpjl2G3IUBud/5s7227 rogid:0GVct78wgjr8E88ZYPr03wY7yr87227 intact-crc:4D3BE695FFBCCFF5|rigid:e0x0A3/0WRdLYdD3ESw9B7y+8XQ false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20227 uniprotkb:P51123 intact:EBI-169179|uniprotkb:Q9W2D8|ensemblmetazoa:FBpp0071596 intact:EBI-499582|uniprotkb:O97068|uniprotkb:Q7KSX6|uniprotkb:Q7KSX7|uniprotkb:Q86LF7|uniprotkb:Q9TX96|ensemblmetazoa:FBpp0089369 psi-mi:tbp_drome(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:CG9874(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:taf1_drome(display_long)|uniprotkb:Transcription initiation factor TFIID 230 kDa subunit(gene name synonym)|uniprotkb:TAFII250(gene name synonym)|uniprotkb:TBP-associated factor 230 kDa(gene name synonym)|uniprotkb:Taf1(gene name)|psi-mi:Taf1(display_short)|uniprotkb:TAF250(gene name synonym)|uniprotkb:CG17603(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874496 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523805.1|flybase:FBgn0003687|ensemblmetazoa:FBgn0003687(gene)|ensemblmetazoa:FBtr0071679(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519|dip:DIP-80N refseq:NP_476956.3|refseq:NP_996159.1|refseq:NP_996160.1|flybase:FBgn0010355|dip:DIP-228N|ensemblmetazoa:FBgn0010355(gene)|ensemblmetazoa:FBtr0081685(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036408"("histone acetyltransferase activity (H3-K14 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR017956|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|rcsb pdb:1TBA|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 pubmed:8349634(see-also)|pubmed:8504928(see-also)|pubmed:8170939(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:eRlX8luNoF4M7SFmEnxKSbI6FJo7227 rogid:DxUDrj8iljY131pQOBswejQxoxI7227 intact-crc:93E7A2FBE9A5ABC7|rigid:yLeqSKuNn3vggmXE3NKJzTy8PnE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P49847 uniprotkb:P51123 intact:EBI-136204|uniprotkb:Q9VW16|uniprotkb:Q961B6|ensemblmetazoa:FBpp0074709 intact:EBI-499582|uniprotkb:O97068|uniprotkb:Q7KSX6|uniprotkb:Q7KSX7|uniprotkb:Q86LF7|uniprotkb:Q9TX96|ensemblmetazoa:FBpp0089369 psi-mi:taf6_drome(display_long)|uniprotkb:Taf6(gene name)|psi-mi:Taf6(display_short)|uniprotkb:Taf60(gene name synonym)|uniprotkb:CG32211(orf name)|uniprotkb:Transcription initiation factor TFIID 62 kDa subunit(gene name synonym)|uniprotkb:TAFII-60(gene name synonym)|uniprotkb:TAFII-62(gene name synonym) psi-mi:taf1_drome(display_long)|uniprotkb:Transcription initiation factor TFIID 230 kDa subunit(gene name synonym)|uniprotkb:TAFII250(gene name synonym)|uniprotkb:TBP-associated factor 230 kDa(gene name synonym)|uniprotkb:Taf1(gene name)|psi-mi:Taf1(display_short)|uniprotkb:TAF250(gene name synonym)|uniprotkb:CG17603(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874500 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524161.2|flybase:FBgn0010417|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR011442(Protein of unknown function DUF1546)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037796|rcsb pdb:1TAF|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|ensemblmetazoa:FBgn0010417(gene)|ensemblmetazoa:FBtr0074941(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|dip:DIP-778N refseq:NP_476956.3|refseq:NP_996159.1|refseq:NP_996160.1|flybase:FBgn0010355|dip:DIP-228N|ensemblmetazoa:FBgn0010355(gene)|ensemblmetazoa:FBtr0081685(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036408"("histone acetyltransferase activity (H3-K14 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR017956|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|rcsb pdb:1TBA|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 pubmed:8262073(see-also)|pubmed:8262073(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:B6rVKKVnmMjwbfPHdfjlEg2QdHs7227 rogid:DxUDrj8iljY131pQOBswejQxoxI7227 intact-crc:E4B861F33F972842|rigid:l347vQ6/YcHDMP5mGxlGsMrJpXA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P47825 uniprotkb:P51123 intact:EBI-277958|uniprotkb:P49845|uniprotkb:Q0E8E3|uniprotkb:Q1LZ31|uniprotkb:Q8T9E0|uniprotkb:Q9VUY7|ensemblmetazoa:FBpp0075205|ensemblmetazoa:FBpp0075206|ensemblmetazoa:FBpp0291125|ensemblmetazoa:FBpp0311865 intact:EBI-499582|uniprotkb:O97068|uniprotkb:Q7KSX6|uniprotkb:Q7KSX7|uniprotkb:Q86LF7|uniprotkb:Q9TX96|ensemblmetazoa:FBpp0089369 psi-mi:taf4_drome(display_long)|uniprotkb:Transcription initiation factor TFIID 110 kDa subunit(gene name synonym)|uniprotkb:110 kDa TBP-associated factor(gene name synonym)|uniprotkb:Taf4(gene name)|psi-mi:Taf4(display_short)|uniprotkb:TAF110(gene name synonym)|uniprotkb:CG5444(orf name) psi-mi:taf1_drome(display_long)|uniprotkb:Transcription initiation factor TFIID 230 kDa subunit(gene name synonym)|uniprotkb:TAFII250(gene name synonym)|uniprotkb:TBP-associated factor 230 kDa(gene name synonym)|uniprotkb:Taf1(gene name)|psi-mi:Taf1(display_short)|uniprotkb:TAF250(gene name synonym)|uniprotkb:CG17603(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874504 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_788511.1|refseq:NP_996101.1|flybase:FBgn0010280|refseq:NP_001287077.1|refseq:NP_001163453.1|refseq:NP_524102.1|refseq:NP_730109.1|dip:DIP-237N|ensemblmetazoa:FBgn0010280(gene)|ensemblmetazoa:FBtr0075448(transcript)|ensemblmetazoa:FBtr0075449(transcript)|ensemblmetazoa:FBtr0301911(transcript)|ensemblmetazoa:FBtr0345951(transcript)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR007900(Transcription initiation factor TFIID component TAF4)|interpro:IPR009072(Histone-fold)|interpro:IPR037249|mint:P47825|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 refseq:NP_476956.3|refseq:NP_996159.1|refseq:NP_996160.1|flybase:FBgn0010355|dip:DIP-228N|ensemblmetazoa:FBgn0010355(gene)|ensemblmetazoa:FBtr0081685(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036408"("histone acetyltransferase activity (H3-K14 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR017956|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|rcsb pdb:1TBA|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 pubmed:8327460(see-also)|pubmed:8464492(see-also)|pubmed:8262073(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:KMwgcLywcp/YxxTLBjtmqXNPhdo7227 rogid:DxUDrj8iljY131pQOBswejQxoxI7227 intact-crc:6910100028968A0F|rigid:+J/IoQ5qKQFviLNDOGd3HT7V1SI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20227 uniprotkb:P49905 intact:EBI-169179|uniprotkb:Q9W2D8|ensemblmetazoa:FBpp0071596 intact:EBI-115002|intact:EBI-1631065|uniprotkb:A4V2Q1|uniprotkb:Q26339|ensemblmetazoa:FBpp0081916|ensemblmetazoa:FBpp0081918|uniprotkb:Q9VGK0 psi-mi:tbp_drome(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:CG9874(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:taf12_drome(display_long)|uniprotkb:Taf12(gene name)|psi-mi:Taf12(display_short)|uniprotkb:p28-alpha/p22(gene name synonym)|uniprotkb:TAF30-ALPHA(gene name synonym)|uniprotkb:TAFII30 alpha(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 28-alpha kDa/22 kDa subunits(gene name synonym)|uniprotkb:CG17358(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874508 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523805.1|flybase:FBgn0003687|ensemblmetazoa:FBgn0003687(gene)|ensemblmetazoa:FBtr0071679(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519|dip:DIP-80N ensemblmetazoa:FBgn0011290(gene)|ensemblmetazoa:FBtr0082440(transcript)|ensemblmetazoa:FBtr0082442(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR003228(Transcription initiation factor TFIID)|interpro:IPR009072(Histone-fold)|interpro:IPR037794|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|refseq:NP_524320.1|refseq:NP_731616.1|refseq:NP_731617.2|flybase:FBgn0011290|refseq:NP_001262479.1|dip:DIP-779N pubmed:8276241(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:eRlX8luNoF4M7SFmEnxKSbI6FJo7227 rogid:WmJM0JQtNVHg0shzMoeQRK6MoWA7227 intact-crc:87910E067EA61268|rigid:Ws5/y83kVhpjum+7GN4nNrg+4ek false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P49905 uniprotkb:Q24325 intact:EBI-115002|intact:EBI-1631065|uniprotkb:A4V2Q1|uniprotkb:Q26339|ensemblmetazoa:FBpp0081916|ensemblmetazoa:FBpp0081918|uniprotkb:Q9VGK0 intact:EBI-141415|ensemblmetazoa:FBpp0076090|ensemblmetazoa:FBpp0304934|uniprotkb:Q8SZR7|uniprotkb:Q9VT64|intact:EBI-1631628 psi-mi:taf12_drome(display_long)|uniprotkb:Taf12(gene name)|psi-mi:Taf12(display_short)|uniprotkb:p28-alpha/p22(gene name synonym)|uniprotkb:TAF30-ALPHA(gene name synonym)|uniprotkb:TAFII30 alpha(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 28-alpha kDa/22 kDa subunits(gene name synonym)|uniprotkb:CG17358(orf name) psi-mi:taf2_drome(display_long)|uniprotkb:Taf2(gene name)|psi-mi:Taf2(display_short)|uniprotkb:TAF150(gene name synonym)|uniprotkb:CG6711(orf name)|uniprotkb:Transcription initiation factor TFIID 150 kDa subunit(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874512 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0011290(gene)|ensemblmetazoa:FBtr0082440(transcript)|ensemblmetazoa:FBtr0082442(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR003228(Transcription initiation factor TFIID)|interpro:IPR009072(Histone-fold)|interpro:IPR037794|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|refseq:NP_524320.1|refseq:NP_731616.1|refseq:NP_731617.2|flybase:FBgn0011290|refseq:NP_001262479.1|dip:DIP-779N reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-73779|ensemblmetazoa:FBgn0011836(gene)|ensemblmetazoa:FBtr0076361(transcript)|ensemblmetazoa:FBtr0332688(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR037813|interpro:IPR042097|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|refseq:NP_729571.1|flybase:FBgn0011836|refseq:NP_001261668.1|dip:DIP-255N pubmed:8276241(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:WmJM0JQtNVHg0shzMoeQRK6MoWA7227 rogid:X8spP5vvdSP/mRH+UROTaTVBt8I7227 intact-crc:4F024DA0FACCC038|rigid:0PF7PUml29CYBVqEeEbEpO1pz/o false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P49906 uniprotkb:Q24325 intact:EBI-187533|uniprotkb:Q9VL90|ensemblmetazoa:FBpp0079514 intact:EBI-141415|ensemblmetazoa:FBpp0076090|ensemblmetazoa:FBpp0304934|uniprotkb:Q8SZR7|uniprotkb:Q9VT64|intact:EBI-1631628 psi-mi:taf11_drome(display_long)|uniprotkb:Taf11(gene name)|psi-mi:Taf11(display_short)|uniprotkb:TAF30-BETA(gene name synonym)|uniprotkb:CG4079(orf name)|uniprotkb:Transcription initiation factor TFIID 28 kDa subunit beta(gene name synonym)|uniprotkb:TAFII30 beta(gene name synonym) psi-mi:taf2_drome(display_long)|uniprotkb:Taf2(gene name)|psi-mi:Taf2(display_short)|uniprotkb:TAF150(gene name synonym)|uniprotkb:CG6711(orf name)|uniprotkb:Transcription initiation factor TFIID 150 kDa subunit(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874516 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_723484.1|flybase:FBgn0011291|dip:DIP-18832N|ensemblmetazoa:FBgn0011291(gene)|ensemblmetazoa:FBtr0079924(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070578"(RISC-loading complex)|go:"GO:1900370"(positive regulation of RNA interference)|interpro:IPR006809(TAFII28-like protein)|interpro:IPR009072(Histone-fold)|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-73779|ensemblmetazoa:FBgn0011836(gene)|ensemblmetazoa:FBtr0076361(transcript)|ensemblmetazoa:FBtr0332688(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR037813|interpro:IPR042097|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|refseq:NP_729571.1|flybase:FBgn0011836|refseq:NP_001261668.1|dip:DIP-255N pubmed:8276241(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NUlIGwxZCnQ7O4euiTqNZV0DWAI7227 rogid:X8spP5vvdSP/mRH+UROTaTVBt8I7227 intact-crc:DF02F9860E5CF3C8|rigid:EyUw0+j7DKQWwGFj7a1uDM9Qfts false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P49906 uniprotkb:P47825 intact:EBI-187533|uniprotkb:Q9VL90|ensemblmetazoa:FBpp0079514 intact:EBI-277958|uniprotkb:P49845|uniprotkb:Q0E8E3|uniprotkb:Q1LZ31|uniprotkb:Q8T9E0|uniprotkb:Q9VUY7|ensemblmetazoa:FBpp0075205|ensemblmetazoa:FBpp0075206|ensemblmetazoa:FBpp0291125|ensemblmetazoa:FBpp0311865 psi-mi:taf11_drome(display_long)|uniprotkb:Taf11(gene name)|psi-mi:Taf11(display_short)|uniprotkb:TAF30-BETA(gene name synonym)|uniprotkb:CG4079(orf name)|uniprotkb:Transcription initiation factor TFIID 28 kDa subunit beta(gene name synonym)|uniprotkb:TAFII30 beta(gene name synonym) psi-mi:taf4_drome(display_long)|uniprotkb:Transcription initiation factor TFIID 110 kDa subunit(gene name synonym)|uniprotkb:110 kDa TBP-associated factor(gene name synonym)|uniprotkb:Taf4(gene name)|psi-mi:Taf4(display_short)|uniprotkb:TAF110(gene name synonym)|uniprotkb:CG5444(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874520 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_723484.1|flybase:FBgn0011291|dip:DIP-18832N|ensemblmetazoa:FBgn0011291(gene)|ensemblmetazoa:FBtr0079924(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070578"(RISC-loading complex)|go:"GO:1900370"(positive regulation of RNA interference)|interpro:IPR006809(TAFII28-like protein)|interpro:IPR009072(Histone-fold)|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 refseq:NP_788511.1|refseq:NP_996101.1|flybase:FBgn0010280|refseq:NP_001287077.1|refseq:NP_001163453.1|refseq:NP_524102.1|refseq:NP_730109.1|dip:DIP-237N|ensemblmetazoa:FBgn0010280(gene)|ensemblmetazoa:FBtr0075448(transcript)|ensemblmetazoa:FBtr0075449(transcript)|ensemblmetazoa:FBtr0301911(transcript)|ensemblmetazoa:FBtr0345951(transcript)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR007900(Transcription initiation factor TFIID component TAF4)|interpro:IPR009072(Histone-fold)|interpro:IPR037249|mint:P47825|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 pubmed:8276241(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NUlIGwxZCnQ7O4euiTqNZV0DWAI7227 rogid:KMwgcLywcp/YxxTLBjtmqXNPhdo7227 intact-crc:4155BCFD9207731D|rigid:CsP0iUiUVGWp0hwCtO9emskp/Bg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P20227 uniprotkb:P49847 intact:EBI-169179|uniprotkb:Q9W2D8|ensemblmetazoa:FBpp0071596 intact:EBI-136204|uniprotkb:Q9VW16|uniprotkb:Q961B6|ensemblmetazoa:FBpp0074709 psi-mi:tbp_drome(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:CG9874(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:taf6_drome(display_long)|uniprotkb:Taf6(gene name)|psi-mi:Taf6(display_short)|uniprotkb:Taf60(gene name synonym)|uniprotkb:CG32211(orf name)|uniprotkb:Transcription initiation factor TFIID 62 kDa subunit(gene name synonym)|uniprotkb:TAFII-60(gene name synonym)|uniprotkb:TAFII-62(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874524 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523805.1|flybase:FBgn0003687|ensemblmetazoa:FBgn0003687(gene)|ensemblmetazoa:FBtr0071679(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519|dip:DIP-80N refseq:NP_524161.2|flybase:FBgn0010417|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR011442(Protein of unknown function DUF1546)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037796|rcsb pdb:1TAF|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|ensemblmetazoa:FBgn0010417(gene)|ensemblmetazoa:FBtr0074941(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|dip:DIP-778N pubmed:8262073(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:eRlX8luNoF4M7SFmEnxKSbI6FJo7227 rogid:B6rVKKVnmMjwbfPHdfjlEg2QdHs7227 intact-crc:FEF60E1748284ECE|rigid:G2Y+YADXcFvpu4UoDEbua0kpXtc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P49906 uniprotkb:P49847 intact:EBI-187533|uniprotkb:Q9VL90|ensemblmetazoa:FBpp0079514 intact:EBI-136204|uniprotkb:Q9VW16|uniprotkb:Q961B6|ensemblmetazoa:FBpp0074709 psi-mi:taf11_drome(display_long)|uniprotkb:Taf11(gene name)|psi-mi:Taf11(display_short)|uniprotkb:TAF30-BETA(gene name synonym)|uniprotkb:CG4079(orf name)|uniprotkb:Transcription initiation factor TFIID 28 kDa subunit beta(gene name synonym)|uniprotkb:TAFII30 beta(gene name synonym) psi-mi:taf6_drome(display_long)|uniprotkb:Taf6(gene name)|psi-mi:Taf6(display_short)|uniprotkb:Taf60(gene name synonym)|uniprotkb:CG32211(orf name)|uniprotkb:Transcription initiation factor TFIID 62 kDa subunit(gene name synonym)|uniprotkb:TAFII-60(gene name synonym)|uniprotkb:TAFII-62(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874528 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_723484.1|flybase:FBgn0011291|dip:DIP-18832N|ensemblmetazoa:FBgn0011291(gene)|ensemblmetazoa:FBtr0079924(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070578"(RISC-loading complex)|go:"GO:1900370"(positive regulation of RNA interference)|interpro:IPR006809(TAFII28-like protein)|interpro:IPR009072(Histone-fold)|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042 refseq:NP_524161.2|flybase:FBgn0010417|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR011442(Protein of unknown function DUF1546)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037796|rcsb pdb:1TAF|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|ensemblmetazoa:FBgn0010417(gene)|ensemblmetazoa:FBtr0074941(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|dip:DIP-778N pubmed:8262073(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:NUlIGwxZCnQ7O4euiTqNZV0DWAI7227 rogid:B6rVKKVnmMjwbfPHdfjlEg2QdHs7227 intact-crc:CCFDCD0E8506D150|rigid:DFNf+SBBsZB87BuKFSe5p+rRCL8 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9XZT7 uniprotkb:Q9VWY6 intact:EBI-127738|ensemblmetazoa:FBpp0077415 intact:EBI-128436|uniprotkb:O18398|uniprotkb:Q8SYE2|ensemblmetazoa:FBpp0074288 psi-mi:tafab_drome(display_long)|uniprotkb:Taf10b(gene name)|psi-mi:Taf10b(display_short)|uniprotkb:Taf16(gene name synonym)|uniprotkb:CG3069(orf name)|uniprotkb:Transcription initiation factor TFIID 16 kDa subunit(gene name synonym)|uniprotkb:"dTAF(II)16"(gene name synonym) psi-mi:taf8_drome(display_long)|uniprotkb:Taf8(gene name)|psi-mi:Taf8(display_short)|uniprotkb:CG7128(orf name)|uniprotkb:pds(gene name synonym)|uniprotkb:prod(gene name synonym)|uniprotkb:Protein prodos(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874532 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477418.1|flybase:FBgn0026324|ensemblmetazoa:FBgn0026324(gene)|ensemblmetazoa:FBtr0077735(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR003923(Transcription initiation factor TFIID, 23-30 kDa subunit)|reactome:R-DME-5689880|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|dip:DIP-19377N refseq:NP_523397.1|flybase:FBgn0022724|ensemblmetazoa:FBgn0022724(gene)|ensemblmetazoa:FBtr0074514(transcript)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR019473|interpro:IPR037818|reactome:R-DME-6807505|go:"GO:0005669"(transcription factor TFIID complex) pubmed:11134347(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:VPvciqsLfMrTt0QyAc+IJjxyoak7227 rogid:ytP0Yu5zBXpGyJD/AczshdAKkqY7227 intact-crc:AF3B9207248C35DB|rigid:pPNEP+6hgHuPHrN3YlDu+6IQmng false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P52654 uniprotkb:P20227 intact:EBI-132413|uniprotkb:Q8IMN7|uniprotkb:Q8IMN8|uniprotkb:Q95RK0|uniprotkb:Q9VB56|ensemblmetazoa:FBpp0084525 intact:EBI-169179|uniprotkb:Q9W2D8|ensemblmetazoa:FBpp0071596 psi-mi:tf2aa_drome(display_long)|uniprotkb:TfIIA-L(gene name)|psi-mi:TfIIA-L(display_short)|uniprotkb:CG5930(orf name)|uniprotkb:General transcription factor IIA subunit 1(gene name synonym)|uniprotkb:dTFIIA-L(gene name synonym) psi-mi:tbp_drome(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:CG9874(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874536 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476995.1|refseq:NP_476996.1|refseq:NP_733208.1|flybase:FBgn0011289|ensemblmetazoa:FBgn0011289(gene)|ensemblmetazoa:FBtr0085155(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0017025"(TBP-class protein binding)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|reactome:R-DME-674695|reactome:R-DME-6807505|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-9018519 refseq:NP_523805.1|flybase:FBgn0003687|ensemblmetazoa:FBgn0003687(gene)|ensemblmetazoa:FBtr0071679(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519|dip:DIP-80N pubmed:8224849(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:UxNzxRQ00IzGKar6wPXbQkPF3O87227 rogid:eRlX8luNoF4M7SFmEnxKSbI6FJo7227 intact-crc:48EAF6409AB0FFEF|rigid:IVrXFnX4GyGvI51AaQhKpNWRDXU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P08953 uniprotkb:Q58S70 intact:EBI-143610|uniprotkb:A4V3G7|uniprotkb:A8WHK7|uniprotkb:Q8MRF3|uniprotkb:Q9VBB8|ensemblmetazoa:FBpp0084431|ensemblmetazoa:FBpp0303188 intact:EBI-870559 psi-mi:toll_drome(display_long)|uniprotkb:Tl(gene name)|psi-mi:Tl(display_short)|uniprotkb:CG5490(orf name) psi-mi:q58s70_drome(display_long)|uniprotkb:Tehao(gene name)|psi-mi:Tehao(display_short)|uniprotkb:CG7121(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874540 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524518.1|refseq:NP_733166.1|flybase:FBgn0262473|dip:DIP-34358N|ensemblmetazoa:FBgn0262473(gene)|ensemblmetazoa:FBtr0085059(transcript)|ensemblmetazoa:FBtr0330155(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002229"(defense response to oomycetes)|go:"GO:0002347"(response to tumor cell)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007507"(heart development)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009597"(detection of virus)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0019955"(cytokine binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046790"(virion binding)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0070976"(TIR domain binding)|go:"GO:1902875"(regulation of embryonic pattern specification)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR026906|interpro:IPR032675|interpro:IPR035897|rcsb pdb:4ARN|rcsb pdb:4ARR|rcsb pdb:4BV4|rcsb pdb:4LXR|rcsb pdb:4LXS|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874 flybase:FBgn0026760|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002807"(positive regulation of antimicrobial peptide biosynthetic process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005121"(Toll binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0015026"(coreceptor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045087"(innate immune response)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR017241(Toll-like receptor)|interpro:IPR032675|interpro:IPR035897 pubmed:11881810(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:6nIbDMNS71rQ+CzvUkspyPjTd707227 rogid:tUWoWWASlihkjMy1WccWibQZfZQ7227 intact-crc:9DBE3B86DE2D1197|rigid:lfX6+OnCV5zohrxYC7cLTOBbtPg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16241 uniprotkb:O15945 intact:EBI-132677|uniprotkb:Q24460|uniprotkb:Q86P26|uniprotkb:Q9VRY9|ensemblmetazoa:FBpp0076653|ensemblmetazoa:FBpp0311831 intact:EBI-172695|uniprotkb:O16167|uniprotkb:O44082|uniprotkb:Q24461|uniprotkb:Q9VHI2|intact:EBI-3417363|ensemblmetazoa:FBpp0081483|ensemblmetazoa:FBpp0307731 psi-mi:cf1a_drome(display_long)|uniprotkb:CG10037(orf name)|uniprotkb:vvl(gene name)|psi-mi:vvl(display_short)|uniprotkb:Cf1a(gene name synonym)|uniprotkb:Chorion factor 1A(gene name synonym)|uniprotkb:Ventral veins lacking protein(gene name synonym)|uniprotkb:Protein drifter(gene name synonym) psi-mi:arnt_drome(display_long)|uniprotkb:tgo(gene name)|psi-mi:tgo(display_short)|uniprotkb:ARNT(gene name synonym)|uniprotkb:HIF-1-beta(gene name synonym)|uniprotkb:CG11987(orf name)|uniprotkb:Protein tango(gene name synonym)|uniprotkb:Hypoxia-inducible factor 1-beta(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874544 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523948.1|flybase:FBgn0086680|refseq:NP_001286957.1|ensemblmetazoa:FBgn0086680(gene)|ensemblmetazoa:FBtr0076944(transcript)|ensemblmetazoa:FBtr0345911(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002807"(positive regulation of antimicrobial peptide biosynthetic process)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0035284"(brain segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR016362(Transcription factor, homeobox/POU)|interpro:IPR017970|dip:DIP-17200N refseq:NP_731308.1|flybase:FBgn0264075|refseq:NP_001262397.1|ensemblmetazoa:FBgn0264075(gene)|ensemblmetazoa:FBtr0082005(transcript)|ensemblmetazoa:FBtr0336755(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008347"(glial cell migration)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0017022"(myosin binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048736"(appendage development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-DME-1234158|reactome:R-DME-8937144 pubmed:10704841(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:5KOEjYBWVSLPmVYoSIRHX3/NbcU7227 rogid:QfQjxuOMC66M3wNk0uC0IggqKbI7227 intact-crc:164C91D6F0976C0B|rigid:FBaO5WpQrWdiRN4asIfbfy9j37o false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24119 uniprotkb:O15945 intact:EBI-867721|uniprotkb:Q24165|uniprotkb:Q8SX13|uniprotkb:Q9W0Q7|uniprotkb:A8JNH0|uniprotkb:A8WHG8|uniprotkb:Q0E8K2|ensemblmetazoa:FBpp0303179 intact:EBI-172695|uniprotkb:O16167|uniprotkb:O44082|uniprotkb:Q24461|uniprotkb:Q9VHI2|intact:EBI-3417363|ensemblmetazoa:FBpp0081483|ensemblmetazoa:FBpp0307731 psi-mi:trh_drome(display_long)|uniprotkb:trh(gene name)|psi-mi:trh(display_short)|uniprotkb:CG6883(orf name) psi-mi:arnt_drome(display_long)|uniprotkb:tgo(gene name)|psi-mi:tgo(display_short)|uniprotkb:ARNT(gene name synonym)|uniprotkb:HIF-1-beta(gene name synonym)|uniprotkb:CG11987(orf name)|uniprotkb:Protein tango(gene name synonym)|uniprotkb:Hypoxia-inducible factor 1-beta(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874548 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036575.1|refseq:NP_001097461.2|refseq:NP_523872.2|flybase:FBgn0262139|refseq:NP_001261207.1|ensemblmetazoa:FBgn0262139(gene)|ensemblmetazoa:FBtr0330146(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007425"(epithelial cell fate determination, open tracheal system)|go:"GO:0007431"(salivary gland development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048736"(appendage development)|go:"GO:0072175"(epithelial tube formation)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638 refseq:NP_731308.1|flybase:FBgn0264075|refseq:NP_001262397.1|ensemblmetazoa:FBgn0264075(gene)|ensemblmetazoa:FBtr0082005(transcript)|ensemblmetazoa:FBtr0336755(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008347"(glial cell migration)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0017022"(myosin binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0048736"(appendage development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-DME-1234158|reactome:R-DME-8937144 pubmed:9284047(see-also)|pubmed:9374395(see-also)|pubmed:9409674(see-also)|pubmed:9521898(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Kpsq6NkJNU789aMg3CMeZGq2kgw7227 rogid:QfQjxuOMC66M3wNk0uC0IggqKbI7227 intact-crc:D643BE969018E536|rigid:MwFphxe3tlCztXCE6Iiey8dPPC4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24326 uniprotkb:Q24306 intact:EBI-869183 intact:EBI-456419|uniprotkb:A4V1Z9|uniprotkb:Q0E8E4|uniprotkb:Q8MRM5|uniprotkb:Q9VUX5|uniprotkb:A9UN33|ensemblmetazoa:FBpp0075254|ensemblmetazoa:FBpp0075255|ensemblmetazoa:FBpp0075256|ensemblmetazoa:FBpp0305793|ensemblmetazoa:FBpp0305794|ensemblmetazoa:FBpp0305795 psi-mi:q24326_drome(display_long)|uniprotkb:tkv(gene name)|psi-mi:tkv(display_short)|uniprotkb:dtfr(gene name synonym)|uniprotkb:CG14026(orf name) psi-mi:diap1_drome(display_long)|uniprotkb:Diap1(gene name)|psi-mi:Diap1(display_short)|uniprotkb:Apoptosis 1 inhibitor(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase th(gene name synonym)|uniprotkb:Iap1(gene name synonym)|uniprotkb:Inhibitor of apoptosis 1(gene name synonym)|uniprotkb:Protein thread(gene name synonym)|uniprotkb:th(gene name synonym)|uniprotkb:CG12284(orf name)|uniprotkb:RING-type E3 ubiquitin transferase Diap1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874552 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0003716|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005025"(transforming growth factor beta receptor activity, type I)|go:"GO:0005524"(ATP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007391"(dorsal closure)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007448"(anterior/posterior pattern specification, imaginal disc)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008354"(germ cell migration)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030721"(spectrosome organization)|go:"GO:0035215"(genital disc development)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0043235"(receptor complex)|go:"GO:0045202"(synapse)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045705"(negative regulation of salivary gland boundary specification)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0046332"(SMAD binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0060799"(transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification)|go:"GO:0061327"(anterior Malpighian tubule development)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|interpro:IPR000333(Activin type II receptor)|interpro:IPR000472(TGF-beta receptor/activin receptor, type I/II)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003605(TGF beta receptor, GS motif)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) refseq:NP_524101.2|refseq:NP_730097.1|refseq:NP_730098.1|flybase:FBgn0260635|refseq:NP_001261916.1|refseq:NP_001261917.1|refseq:NP_001261918.1|go:"GO:0006915"(apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0022416"(chaeta development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0045116"(protein neddylation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|ensemblmetazoa:FBgn0260635(gene)|ensemblmetazoa:FBtr0075499(transcript)|ensemblmetazoa:FBtr0075500(transcript)|ensemblmetazoa:FBtr0075501(transcript)|ensemblmetazoa:FBtr0333617(transcript)|ensemblmetazoa:FBtr0333618(transcript)|ensemblmetazoa:FBtr0333619(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|mint:Q24306|rcsb pdb:1JD4|rcsb pdb:1JD5|rcsb pdb:1JD6|rcsb pdb:1Q4Q|rcsb pdb:1SDZ|rcsb pdb:1SE0|rcsb pdb:3SIP|rcsb pdb:3SIQ|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-3769402|reactome:R-DME-390150|reactome:R-DME-5675482|reactome:R-DME-8948747|reactome:R-DME-8948751 pubmed:9545255(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:FB2IWkOHoz7sCHdulTN4juLDwhk7227 rogid:loBQ//cKQ1NYhq3gnIKwRBn5vZg7227 intact-crc:B230273C7ED5664A|rigid:dQQt6x0o4cxl50Ih9qL+Y/iv3lc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q8IR23 uniprotkb:P18475 intact:EBI-868068|ensemblmetazoa:FBpp0073945|ensemblmetazoa:FBpp0073946|ensemblmetazoa:FBpp0089147|ensemblmetazoa:FBpp0089148|ensemblmetazoa:FBpp0309361|ensemblmetazoa:FBpp0309362 intact:EBI-195402|uniprotkb:A8DY54|uniprotkb:A8DY56|uniprotkb:Q9V4R2|ensemblmetazoa:FBpp0088012 psi-mi:q8ir23_drome(display_long)|uniprotkb:D-RasGAP(gene name synonym)|uniprotkb:Dmel\CG9209(gene name synonym)|uniprotkb:FBpp0073946(gene name synonym)|uniprotkb:RAS-GAP(gene name synonym)|uniprotkb:RasGAP(gene name synonym)|uniprotkb:Vap(gene name synonym)|uniprotkb:p120RasGAP(gene name synonym)|uniprotkb:rasGap(gene name synonym)|uniprotkb:vap(gene name)|psi-mi:vap(display_short)|uniprotkb:RasGap(gene name synonym)|uniprotkb:Dmel_CG9209(orf name)|uniprotkb:p120 RasGAP(gene name synonym)|uniprotkb:vap-RA(gene name synonym)|uniprotkb:CG9209(orf name) psi-mi:torso_drome(display_long)|uniprotkb:tor(gene name)|psi-mi:tor(display_short)|uniprotkb:CG1389(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874556 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523361.1|refseq:NP_727925.1|refseq:NP_727926.2|refseq:NP_996482.1|flybase:FBgn0003969|refseq:NP_001285314.1|refseq:NP_001285315.1|ensemblmetazoa:FBgn0003969(gene)|ensemblmetazoa:FBtr0074140(transcript)|ensemblmetazoa:FBtr0074141(transcript)|ensemblmetazoa:FBtr0074142(transcript)|ensemblmetazoa:FBtr0074143(transcript)|ensemblmetazoa:FBtr0340415(transcript)|ensemblmetazoa:FBtr0340416(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005122"(torso binding)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016319"(mushroom body development)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0120177"(negative regulation of torso signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023152|interpro:IPR028554|interpro:IPR035652|interpro:IPR035841|interpro:IPR035842|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|interpro:IPR039360|mint:Q8IR23|reactome:R-DME-186763|reactome:R-DME-3928662|reactome:R-DME-5218921|reactome:R-DME-8849471 refseq:NP_001097212.2|refseq:NP_476762.1|flybase:FBgn0003733|ensemblmetazoa:FBgn0003733(gene)|ensemblmetazoa:FBtr0088938(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007278"(pole cell fate determination)|go:"GO:0007280"(pole cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0046957"(negative phototaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116 pubmed:9885560(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:Qc4rc5oeH6PrmaZ75RzhCWjUYgU7227 rogid:xto08nbumwFlew52tyO4IgeMEqs7227 intact-crc:6C090F6CD8EA6E04|rigid:6VPpdoPc+s/ftH5cOa9AWT7TaKY false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24155 uniprotkb:P18475 intact:EBI-137587|uniprotkb:Q9VL09|ensemblmetazoa:FBpp0079667 intact:EBI-195402|uniprotkb:A8DY54|uniprotkb:A8DY56|uniprotkb:Q9V4R2|ensemblmetazoa:FBpp0088012 psi-mi:trunk_drome(display_long)|uniprotkb:trk(gene name)|psi-mi:trk(display_short)|uniprotkb:CG5619(orf name) psi-mi:torso_drome(display_long)|uniprotkb:tor(gene name)|psi-mi:tor(display_short)|uniprotkb:CG1389(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874560 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476767.2|flybase:FBgn0003751|ensemblmetazoa:FBgn0003751(gene)|ensemblmetazoa:FBtr0080078(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005122"(torso binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007362"(terminal region determination)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0048018"(receptor ligand activity)|interpro:IPR029034 refseq:NP_001097212.2|refseq:NP_476762.1|flybase:FBgn0003733|ensemblmetazoa:FBgn0003733(gene)|ensemblmetazoa:FBtr0088938(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007278"(pole cell fate determination)|go:"GO:0007280"(pole cell migration)|go:"GO:0007362"(terminal region determination)|go:"GO:0007369"(gastrulation)|go:"GO:0007552"(metamorphosis)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0046957"(negative phototaxis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116 pubmed:7590233(see-also)|pubmed:11290307(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:eJKvrWDcE1A4c6tv277Ym0mkVaA7227 rogid:xto08nbumwFlew52tyO4IgeMEqs7227 intact-crc:8EDA352EA6224C1B|rigid:+LMr9w1WP6gIVqUpepRY4E9h7OU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P19018 uniprotkb:P11596 intact:EBI-198424|uniprotkb:A4UZH1|uniprotkb:Q0E977|uniprotkb:Q9V734|ensemblmetazoa:FBpp0088562|ensemblmetazoa:FBpp0088946|ensemblmetazoa:FBpp0088947 intact:EBI-157553|ensemblmetazoa:FBpp0075123|uniprotkb:Q540G8|uniprotkb:Q86LR9|uniprotkb:Q9VV78 psi-mi:tra2_drome(display_long)|uniprotkb:tra2(gene name)|psi-mi:tra2(display_short)|uniprotkb:tra-2(gene name synonym)|uniprotkb:CG10128(orf name) psi-mi:trsf_drome(display_long)|uniprotkb:tra(gene name)|psi-mi:tra(display_short)|uniprotkb:CG16724(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874564 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476763.1|refseq:NP_476764.1|refseq:NP_476765.1|refseq:NP_476766.1|refseq:NP_599107.1|refseq:NP_995834.1|refseq:NP_995835.1|flybase:FBgn0003742|dip:DIP-17430N|ensemblmetazoa:FBgn0003742(gene)|ensemblmetazoa:FBtr0089617(transcript)|ensemblmetazoa:FBtr0089620(transcript)|ensemblmetazoa:FBtr0089621(transcript)|go:"GO:0000003"(reproduction)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0019101"(female somatic sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030237"(female sex determination)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-DME-6791226|reactome:R-DME-72163|reactome:R-DME-9013418|reactome:R-DME-9013422 ensemblmetazoa:FBgn0003741(gene)|ensemblmetazoa:FBtr0075364(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018993"(somatic sex determination)|go:"GO:0019101"(female somatic sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030237"(female sex determination)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0046660"(female sex differentiation)|go:"GO:1990399"(epithelium regeneration)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR010519(Fruit fly transformer)|refseq:NP_524114.1|flybase:FBgn0003741 pubmed:8124712(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:uL8i3jhKpNlSUIxgCb/9lb1L/1E7227 rogid:4lOBLnwE6CFXcVNKtK96XSW+zx07227 intact-crc:6CFAB96E740B8CFB|rigid:Ji2nNL2tO2GkDQiBq5I1CjWIOLg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P19018 uniprotkb:P19018 intact:EBI-198424|uniprotkb:A4UZH1|uniprotkb:Q0E977|uniprotkb:Q9V734|ensemblmetazoa:FBpp0088562|ensemblmetazoa:FBpp0088946|ensemblmetazoa:FBpp0088947 intact:EBI-198424|uniprotkb:A4UZH1|uniprotkb:Q0E977|uniprotkb:Q9V734|ensemblmetazoa:FBpp0088562|ensemblmetazoa:FBpp0088946|ensemblmetazoa:FBpp0088947 psi-mi:tra2_drome(display_long)|uniprotkb:tra2(gene name)|psi-mi:tra2(display_short)|uniprotkb:tra-2(gene name synonym)|uniprotkb:CG10128(orf name) psi-mi:tra2_drome(display_long)|uniprotkb:tra2(gene name)|psi-mi:tra2(display_short)|uniprotkb:tra-2(gene name synonym)|uniprotkb:CG10128(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874568 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476763.1|refseq:NP_476764.1|refseq:NP_476765.1|refseq:NP_476766.1|refseq:NP_599107.1|refseq:NP_995834.1|refseq:NP_995835.1|flybase:FBgn0003742|dip:DIP-17430N|ensemblmetazoa:FBgn0003742(gene)|ensemblmetazoa:FBtr0089617(transcript)|ensemblmetazoa:FBtr0089620(transcript)|ensemblmetazoa:FBtr0089621(transcript)|go:"GO:0000003"(reproduction)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0019101"(female somatic sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030237"(female sex determination)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-DME-6791226|reactome:R-DME-72163|reactome:R-DME-9013418|reactome:R-DME-9013422 refseq:NP_476763.1|refseq:NP_476764.1|refseq:NP_476765.1|refseq:NP_476766.1|refseq:NP_599107.1|refseq:NP_995834.1|refseq:NP_995835.1|flybase:FBgn0003742|dip:DIP-17430N|ensemblmetazoa:FBgn0003742(gene)|ensemblmetazoa:FBtr0089617(transcript)|ensemblmetazoa:FBtr0089620(transcript)|ensemblmetazoa:FBtr0089621(transcript)|go:"GO:0000003"(reproduction)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0019101"(female somatic sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030237"(female sex determination)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-DME-6791226|reactome:R-DME-72163|reactome:R-DME-9013418|reactome:R-DME-9013422 pubmed:8124712(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:uL8i3jhKpNlSUIxgCb/9lb1L/1E7227 rogid:uL8i3jhKpNlSUIxgCb/9lb1L/1E7227 intact-crc:6E74392FCCC311C1|rigid:oYHc7J25f1okcx8oC86/Bbtv2CI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P16241 uniprotkb:Q24119 intact:EBI-132677|uniprotkb:Q24460|uniprotkb:Q86P26|uniprotkb:Q9VRY9|ensemblmetazoa:FBpp0076653|ensemblmetazoa:FBpp0311831 intact:EBI-867721|uniprotkb:Q24165|uniprotkb:Q8SX13|uniprotkb:Q9W0Q7|uniprotkb:A8JNH0|uniprotkb:A8WHG8|uniprotkb:Q0E8K2|ensemblmetazoa:FBpp0303179 psi-mi:cf1a_drome(display_long)|uniprotkb:CG10037(orf name)|uniprotkb:vvl(gene name)|psi-mi:vvl(display_short)|uniprotkb:Cf1a(gene name synonym)|uniprotkb:Chorion factor 1A(gene name synonym)|uniprotkb:Ventral veins lacking protein(gene name synonym)|uniprotkb:Protein drifter(gene name synonym) psi-mi:trh_drome(display_long)|uniprotkb:trh(gene name)|psi-mi:trh(display_short)|uniprotkb:CG6883(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874572 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523948.1|flybase:FBgn0086680|refseq:NP_001286957.1|ensemblmetazoa:FBgn0086680(gene)|ensemblmetazoa:FBtr0076944(transcript)|ensemblmetazoa:FBtr0345911(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002807"(positive regulation of antimicrobial peptide biosynthetic process)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0035284"(brain segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR016362(Transcription factor, homeobox/POU)|interpro:IPR017970|dip:DIP-17200N refseq:NP_001036575.1|refseq:NP_001097461.2|refseq:NP_523872.2|flybase:FBgn0262139|refseq:NP_001261207.1|ensemblmetazoa:FBgn0262139(gene)|ensemblmetazoa:FBtr0330146(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007425"(epithelial cell fate determination, open tracheal system)|go:"GO:0007431"(salivary gland development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0035202"(tracheal pit formation in open tracheal system)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048736"(appendage development)|go:"GO:0072175"(epithelial tube formation)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638 pubmed:10704841(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:5KOEjYBWVSLPmVYoSIRHX3/NbcU7227 rogid:Kpsq6NkJNU789aMg3CMeZGq2kgw7227 intact-crc:C28C494DED771536|rigid:9mM89yu9O/4SgFuF0JOKk05Htag false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42282 uniprotkb:Q08605 intact:EBI-77008|uniprotkb:A4V3Q3|uniprotkb:Q0KHY0|uniprotkb:Q1LZ43|uniprotkb:Q24313|uniprotkb:Q9V9V2|ensemblmetazoa:FBpp0085186|ensemblmetazoa:FBpp0085188|ensemblmetazoa:FBpp0085190|ensemblmetazoa:FBpp0292319 intact:EBI-300317|uniprotkb:Q08083|uniprotkb:Q7JN57|uniprotkb:Q8MYL3|uniprotkb:Q8T387|uniprotkb:Q9V3X7|uniprotkb:Q9VUH2|uniprotkb:O18349|uniprotkb:O18350|uniprotkb:O18526 psi-mi:ttka_drome(display_long)|uniprotkb:ttk(gene name)|psi-mi:ttk(display_short)|uniprotkb:FTZ-F2(gene name synonym)|uniprotkb:CG1856(orf name)|uniprotkb:Tramtrack p88(gene name synonym)|uniprotkb:Repressor protein fushi tarazu(gene name synonym) psi-mi:gaga_drome(display_long)|uniprotkb:Trl(gene name)|psi-mi:Trl(display_short)|uniprotkb:GAGA(gene name synonym)|uniprotkb:TFGAGA(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:GAGA factor(gene name synonym)|uniprotkb:Adh transcription factor 2(gene name synonym)|uniprotkb:Neural conserved at 70F(gene name synonym)|uniprotkb:Adf-2(gene name synonym)|uniprotkb:Nc70F(gene name synonym)|uniprotkb:CG33261(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874576 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189329.1|refseq:NP_733443.1|refseq:NP_733444.1|refseq:NP_733445.1|flybase:FBgn0003870|ensemblmetazoa:FBgn0003870(gene)|ensemblmetazoa:FBtr0085825(transcript)|ensemblmetazoa:FBtr0085827(transcript)|ensemblmetazoa:FBtr0085829(transcript)|ensemblmetazoa:FBtr0303227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031208"(POZ domain binding)|go:"GO:0035001"(dorsal trunk growth, open tracheal system)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035151"(regulation of tube size, open tracheal system)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042682"(regulation of compound eye cone cell fate specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045677"(negative regulation of R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048053"(R1/R6 development)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048750"(compound eye corneal lens morphogenesis)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 go:"GO:0000280"(nuclear division)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007549"(dosage compensation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0034728"(nucleosome organization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051301"(cell division)|go:"GO:1901409"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:1990000"(amyloid fibril formation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR015318(Zinc finger, GAGAG binding factor)|rcsb pdb:1YUI|rcsb pdb:1YUJ|go:"GO:0035075"(response to ecdysone)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043044"|refseq:NP_001034014.1|refseq:NP_996077.1|refseq:NP_996078.1|refseq:NP_996079.1|refseq:NP_996080.1|refseq:NP_996081.1|refseq:NP_996082.1|flybase:FBgn0013263 pubmed:12384587(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:k0MeF2/ch3ddqz7uLHjP8aeJwoI7227 rogid:s2lpiYJCLr9x3aKiQRvlG3gE9nk7227 intact-crc:C193A94CC1F4FF04|rigid:gTwLEIjHnWEoGPAn74tD9mQKObk false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P19334 uniprotkb:P48994 intact:EBI-165136|uniprotkb:Q7YU76|uniprotkb:Q9VAE1|ensemblmetazoa:FBpp0084879 intact:EBI-98143|uniprotkb:Q0E9E3|uniprotkb:Q8IH62|uniprotkb:Q8MKU9|uniprotkb:Q9V5B2|intact:EBI-3407987|uniprotkb:C6TPC1|ensemblmetazoa:FBpp0087555|ensemblmetazoa:FBpp0087557|ensemblmetazoa:FBpp0290876 psi-mi:trp_drome(display_long)|uniprotkb:trp(gene name)|psi-mi:trp(display_short)|uniprotkb:CG7875(orf name) psi-mi:trpl_drome(display_long)|uniprotkb:trpl(gene name)|psi-mi:trpl(display_short)|uniprotkb:CG18345(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874580 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476768.1|flybase:FBgn0003861|ensemblmetazoa:FBgn0003861(gene)|ensemblmetazoa:FBtr0085513(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006828"(manganese ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007602"(phototransduction)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008104"(protein localization)|go:"GO:0008355"(olfactory learning)|go:"GO:0008377"(light-induced release of internally sequestered calcium ion)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010461"(light-activated ion channel activity)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0034703"(cation channel complex)|go:"GO:0035997"(rhabdomere microvillus membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0050962"(detection of light stimulus involved in sensory perception)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:0098662"(inorganic cation transmembrane transport)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|rcsb pdb:5F67|rcsb pdb:7CQH|rcsb pdb:7CQV|reactome:R-DME-114508|reactome:R-DME-139853|reactome:R-DME-3295583|reactome:R-DME-5578775|reactome:R-DME-983695 refseq:NP_476895.1|refseq:NP_724822.1|refseq:NP_724823.2|flybase:FBgn0005614|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071454"(cellular response to anoxia)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-114508|reactome:R-DME-139853|reactome:R-DME-3295583|reactome:R-DME-5578775|reactome:R-DME-983695|ensemblmetazoa:FBgn0005614(gene)|ensemblmetazoa:FBtr0088471(transcript)|ensemblmetazoa:FBtr0088473(transcript)|ensemblmetazoa:FBtr0301662(transcript)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006828"(manganese ion transport)|go:"GO:0007589"(body fluid secretion)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010461"(light-activated ion channel activity)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0034703"(cation channel complex)|go:"GO:0035997"(rhabdomere microvillus membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070588"(calcium ion transmembrane transport) pubmed:9215637(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:CZ/nZUylQKoS0GQ3jKaucCw8gjo7227 rogid:glMABf53+ZJj3aUROdZNs7ts6Bc7227 intact-crc:0798D5B1623A86A3|rigid:vI9yl5EbRuByaS9zd6iSiYedvqg false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P48994 uniprotkb:Q9VJJ7 intact:EBI-98143|uniprotkb:Q0E9E3|uniprotkb:Q8IH62|uniprotkb:Q8MKU9|uniprotkb:Q9V5B2|intact:EBI-3407987|uniprotkb:C6TPC1|ensemblmetazoa:FBpp0087555|ensemblmetazoa:FBpp0087557|ensemblmetazoa:FBpp0290876 intact:EBI-133256|uniprotkb:A4V0S8|uniprotkb:Q9N6L1|ensemblmetazoa:FBpp0080498|ensemblmetazoa:FBpp0080499 psi-mi:trpl_drome(display_long)|uniprotkb:trpl(gene name)|psi-mi:trpl(display_short)|uniprotkb:CG18345(orf name) psi-mi:trpg_drome(display_long)|uniprotkb:Trpgamma(gene name)|psi-mi:Trpgamma(display_short)|uniprotkb:Transient receptor potential cation channel gamma(gene name synonym)|uniprotkb:CG5996(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874584 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476895.1|refseq:NP_724822.1|refseq:NP_724823.2|flybase:FBgn0005614|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071454"(cellular response to anoxia)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-114508|reactome:R-DME-139853|reactome:R-DME-3295583|reactome:R-DME-5578775|reactome:R-DME-983695|ensemblmetazoa:FBgn0005614(gene)|ensemblmetazoa:FBtr0088471(transcript)|ensemblmetazoa:FBtr0088473(transcript)|ensemblmetazoa:FBtr0301662(transcript)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006828"(manganese ion transport)|go:"GO:0007589"(body fluid secretion)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010461"(light-activated ion channel activity)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0034703"(cation channel complex)|go:"GO:0035997"(rhabdomere microvillus membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070588"(calcium ion transmembrane transport) refseq:NP_609802.1|refseq:NP_723983.1|flybase:FBgn0032593|ensemblmetazoa:FBgn0032593(gene)|ensemblmetazoa:FBtr0080945(transcript)|ensemblmetazoa:FBtr0080946(transcript)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006828"(manganese ion transport)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008381"(mechanosensitive ion channel activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016028"(rhabdomere)|go:"GO:0034703"(cation channel complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:1990635"(proximal dendrite)|interpro:IPR002110(Ankyrin)|interpro:IPR002153(Transient receptor potential protein)|interpro:IPR005821(Ion transport)|interpro:IPR013555(Transient receptor potential II)|interpro:IPR036770|reactome:R-DME-114508|reactome:R-DME-139853|reactome:R-DME-3295583|reactome:R-DME-5578775|reactome:R-DME-983695 pubmed:10896160(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:glMABf53+ZJj3aUROdZNs7ts6Bc7227 rogid:csqriQv0So9xmZAHbZcPDpJAMC87227 intact-crc:3EF8C9D119F0F3EF|rigid:DhmKn1horvnpEYd4fOEPyMPDieA false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P42282 uniprotkb:P42282 intact:EBI-77008|uniprotkb:A4V3Q3|uniprotkb:Q0KHY0|uniprotkb:Q1LZ43|uniprotkb:Q24313|uniprotkb:Q9V9V2|ensemblmetazoa:FBpp0085186|ensemblmetazoa:FBpp0085188|ensemblmetazoa:FBpp0085190|ensemblmetazoa:FBpp0292319 intact:EBI-77008|uniprotkb:A4V3Q3|uniprotkb:Q0KHY0|uniprotkb:Q1LZ43|uniprotkb:Q24313|uniprotkb:Q9V9V2|ensemblmetazoa:FBpp0085186|ensemblmetazoa:FBpp0085188|ensemblmetazoa:FBpp0085190|ensemblmetazoa:FBpp0292319 psi-mi:ttka_drome(display_long)|uniprotkb:ttk(gene name)|psi-mi:ttk(display_short)|uniprotkb:FTZ-F2(gene name synonym)|uniprotkb:CG1856(orf name)|uniprotkb:Tramtrack p88(gene name synonym)|uniprotkb:Repressor protein fushi tarazu(gene name synonym) psi-mi:ttka_drome(display_long)|uniprotkb:ttk(gene name)|psi-mi:ttk(display_short)|uniprotkb:FTZ-F2(gene name synonym)|uniprotkb:CG1856(orf name)|uniprotkb:Tramtrack p88(gene name synonym)|uniprotkb:Repressor protein fushi tarazu(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874588 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189329.1|refseq:NP_733443.1|refseq:NP_733444.1|refseq:NP_733445.1|flybase:FBgn0003870|ensemblmetazoa:FBgn0003870(gene)|ensemblmetazoa:FBtr0085825(transcript)|ensemblmetazoa:FBtr0085827(transcript)|ensemblmetazoa:FBtr0085829(transcript)|ensemblmetazoa:FBtr0303227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031208"(POZ domain binding)|go:"GO:0035001"(dorsal trunk growth, open tracheal system)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035151"(regulation of tube size, open tracheal system)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042682"(regulation of compound eye cone cell fate specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045677"(negative regulation of R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048053"(R1/R6 development)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048750"(compound eye corneal lens morphogenesis)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 refseq:NP_001189329.1|refseq:NP_733443.1|refseq:NP_733444.1|refseq:NP_733445.1|flybase:FBgn0003870|ensemblmetazoa:FBgn0003870(gene)|ensemblmetazoa:FBtr0085825(transcript)|ensemblmetazoa:FBtr0085827(transcript)|ensemblmetazoa:FBtr0085829(transcript)|ensemblmetazoa:FBtr0303227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031208"(POZ domain binding)|go:"GO:0035001"(dorsal trunk growth, open tracheal system)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035151"(regulation of tube size, open tracheal system)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042682"(regulation of compound eye cone cell fate specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045677"(negative regulation of R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048053"(R1/R6 development)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048750"(compound eye corneal lens morphogenesis)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 pubmed:12204250(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:k0MeF2/ch3ddqz7uLHjP8aeJwoI7227 rogid:k0MeF2/ch3ddqz7uLHjP8aeJwoI7227 intact-crc:D6EF30F16E7A4C3C|rigid:M70+RIWgNrrLBq2BeyXItpOK1O4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P10627 uniprotkb:P10627 intact:EBI-104826|uniprotkb:Q8MT07|uniprotkb:Q8T8Y9|uniprotkb:Q9W1W1|uniprotkb:Q1LZ34|ensemblmetazoa:FBpp0071864|ensemblmetazoa:FBpp0099476|ensemblmetazoa:FBpp0311714 intact:EBI-104826|uniprotkb:Q8MT07|uniprotkb:Q8T8Y9|uniprotkb:Q9W1W1|uniprotkb:Q1LZ34|ensemblmetazoa:FBpp0071864|ensemblmetazoa:FBpp0099476|ensemblmetazoa:FBpp0311714 psi-mi:twist_drome(display_long)|uniprotkb:twi(gene name)|psi-mi:twi(display_short)|uniprotkb:CG2956(orf name) psi-mi:twist_drome(display_long)|uniprotkb:twi(gene name)|psi-mi:twi(display_short)|uniprotkb:CG2956(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874592 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033967.1|refseq:NP_523816.2|flybase:FBgn0003900|refseq:NP_001286752.1|ensemblmetazoa:FBgn0003900(gene)|ensemblmetazoa:FBtr0071953(transcript)|ensemblmetazoa:FBtr0100130(transcript)|ensemblmetazoa:FBtr0345653(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0007507"(heart development)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032502"(developmental process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0055001"(muscle cell development)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015789(Twist)|interpro:IPR036638 refseq:NP_001033967.1|refseq:NP_523816.2|flybase:FBgn0003900|refseq:NP_001286752.1|ensemblmetazoa:FBgn0003900(gene)|ensemblmetazoa:FBtr0071953(transcript)|ensemblmetazoa:FBtr0100130(transcript)|ensemblmetazoa:FBtr0345653(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007443"(Malpighian tubule morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0007507"(heart development)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032502"(developmental process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0055001"(muscle cell development)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015789(Twist)|interpro:IPR036638 pubmed:11688563(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:opc0LqFf1LFamPnLiKVnBlMgYzs7227 rogid:opc0LqFf1LFamPnLiKVnBlMgYzs7227 intact-crc:4A53D5D5A550EFC3|rigid:rBd5eDtJvbFCybl/jyCS5LDMWe0 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q94535 uniprotkb:Q24562 intact:EBI-121011|uniprotkb:Q9VPN4|ensemblmetazoa:FBpp0077792|ensemblmetazoa:FBpp0305600 intact:EBI-165226|uniprotkb:Q9VXH2|ensemblmetazoa:FBpp0074013|ensemblmetazoa:FBpp0298007 psi-mi:u2af1_drome(display_long)|uniprotkb:U2af38(gene name)|psi-mi:U2af38(display_short)|uniprotkb:CG3582(orf name)|uniprotkb:U2 auxiliary factor 38 kDa subunit(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor small subunit(gene name synonym) psi-mi:u2af2_drome(display_long)|uniprotkb:U2af50(gene name)|psi-mi:U2af50(display_short)|uniprotkb:CG9998(orf name)|uniprotkb:U2 auxiliary factor 50 kDa subunit(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor large subunit(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874596 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477208.1|flybase:FBgn0017457|ensemblmetazoa:FBgn0017457(gene)|ensemblmetazoa:FBtr0078133(transcript)|ensemblmetazoa:FBtr0333408(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR009145(U2 auxiliary factor small subunit)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-DME-159236|reactome:R-DME-72163|reactome:R-DME-72187|reactome:R-DME-73856|refseq:NP_001259814.1|dip:DIP-23299N refseq:NP_001245710.1|refseq:NP_476891.1|flybase:FBgn0005411|ensemblmetazoa:FBgn0005411(gene)|ensemblmetazoa:FBtr0074234(transcript)|ensemblmetazoa:FBtr0307178(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051168"(nuclear export)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006529(U2 snRNP auxilliary factor, large subunit, splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-DME-159236|reactome:R-DME-72163|reactome:R-DME-72187|reactome:R-DME-73856|dip:DIP-23323N pubmed:9528748(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:+bqsp/StCySByYEpSvoorP2hoRI7227 rogid:xSz9Dzo5kqYOSLEX/KbA5+ciURs7227 intact-crc:33BA11102B838015|rigid:FWyAmV/f7PKIQGim0auhpXk0IoM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P09956 uniprotkb:P09956 intact:EBI-167915|uniprotkb:Q24596|uniprotkb:Q9V3F1|ensemblmetazoa:FBpp0070419 intact:EBI-167915|uniprotkb:Q24596|uniprotkb:Q9V3F1|ensemblmetazoa:FBpp0070419 psi-mi:zest_drome(display_long)|uniprotkb:z(gene name)|psi-mi:z(display_short)|uniprotkb:CG7803(orf name) psi-mi:zest_drome(display_long)|uniprotkb:z(gene name)|psi-mi:z(display_short)|uniprotkb:CG7803(orf name) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-874600 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033827.1|refseq:NP_525051.1|flybase:FBgn0004050|ensemblmetazoa:FBgn0004050(gene)|ensemblmetazoa:FBtr0070435(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006727"(ommochrome biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR028002|rcsb pdb:5CQQ refseq:NP_001033827.1|refseq:NP_525051.1|flybase:FBgn0004050|ensemblmetazoa:FBgn0004050(gene)|ensemblmetazoa:FBtr0070435(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0006727"(ommochrome biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR028002|rcsb pdb:5CQQ pubmed:9560400(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:bQxVJ2t/BzEBjBP6tudSESDRYd87227 rogid:bQxVJ2t/BzEBjBP6tudSESDRYd87227 intact-crc:C55AFE3788F41AD6|rigid:RBXIUubrB/TOhi7+22b2kcErsL4 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q24106 uniprotkb:Q24306 intact:EBI-135509|uniprotkb:Q9VVP1|ensemblmetazoa:FBpp0074899|ensemblmetazoa:FBpp0305084 intact:EBI-456419|uniprotkb:A4V1Z9|uniprotkb:Q0E8E4|uniprotkb:Q8MRM5|uniprotkb:Q9VUX5|uniprotkb:A9UN33|ensemblmetazoa:FBpp0075254|ensemblmetazoa:FBpp0075255|ensemblmetazoa:FBpp0075256|ensemblmetazoa:FBpp0305793|ensemblmetazoa:FBpp0305794|ensemblmetazoa:FBpp0305795 psi-mi:hid_drome(display_long)|uniprotkb:hid(gene name)|psi-mi:hid(display_short)|uniprotkb:Protein head involution defective(gene name synonym)|uniprotkb:Protein wrinkled(gene name synonym)|uniprotkb:W(gene name synonym)|uniprotkb:CG5123(orf name) psi-mi:diap1_drome(display_long)|uniprotkb:Diap1(gene name)|psi-mi:Diap1(display_short)|uniprotkb:Apoptosis 1 inhibitor(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase th(gene name synonym)|uniprotkb:Iap1(gene name synonym)|uniprotkb:Inhibitor of apoptosis 1(gene name synonym)|uniprotkb:Protein thread(gene name synonym)|uniprotkb:th(gene name synonym)|uniprotkb:CG12284(orf name)|uniprotkb:RING-type E3 ubiquitin transferase Diap1(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) - pubmed:unassigned4 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-876200 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524136.2|flybase:FBgn0003997|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008219"(cell death)|go:"GO:0008258"(head involution)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010114"(response to red light)|go:"GO:0012501"(programmed cell death)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035071"(salivary gland cell autophagic cell death)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005739"(mitochondrion)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1904747"(positive regulation of apoptotic process involved in development)|go:"GO:1990525"(BIR domain binding)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|rcsb pdb:1JD6|ensemblmetazoa:FBgn0003997(gene)|ensemblmetazoa:FBtr0075133(transcript)|ensemblmetazoa:FBtr0332862(transcript)|go:"GO:0002165"(instar larval or pupal development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|refseq:NP_001262010.1|dip:DIP-20052N refseq:NP_524101.2|refseq:NP_730097.1|refseq:NP_730098.1|flybase:FBgn0260635|refseq:NP_001261916.1|refseq:NP_001261917.1|refseq:NP_001261918.1|go:"GO:0006915"(apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0022416"(chaeta development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0045116"(protein neddylation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0089720"(caspase binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|ensemblmetazoa:FBgn0260635(gene)|ensemblmetazoa:FBtr0075499(transcript)|ensemblmetazoa:FBtr0075500(transcript)|ensemblmetazoa:FBtr0075501(transcript)|ensemblmetazoa:FBtr0333617(transcript)|ensemblmetazoa:FBtr0333618(transcript)|ensemblmetazoa:FBtr0333619(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|mint:Q24306|rcsb pdb:1JD4|rcsb pdb:1JD5|rcsb pdb:1JD6|rcsb pdb:1Q4Q|rcsb pdb:1SDZ|rcsb pdb:1SE0|rcsb pdb:3SIP|rcsb pdb:3SIQ|reactome:R-DME-111465|reactome:R-DME-111469|reactome:R-DME-3769402|reactome:R-DME-390150|reactome:R-DME-5675482|reactome:R-DME-8948747|reactome:R-DME-8948751 pubmed:9584170(see-also)|pubmed:10655220(see-also)|pubmed:11511363(see-also) - - curation depth:mimix curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/02/27 2014/10/16 rogid:x/Jsu6gdz5rnLlOny3LOrreZP2c7227 rogid:loBQ//cKQ1NYhq3gnIKwRBn5vZg7227 intact-crc:2D36E53CA6D8DD2A|rigid:/Z8/PY4Z0kOqpEkt1M5o+hUp57g false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification)