#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O60238 uniprotkb:Q92934 intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003 intact:EBI-700771|uniprotkb:O14803|uniprotkb:Q6FH21|ensembl:ENSP00000309103|ensembl:ENSP00000378040 psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym) psi-mi:bad_human(display_long)|uniprotkb:Bcl-2-binding component 6(gene name synonym)|uniprotkb:Bcl-2-like protein 8(gene name synonym)|uniprotkb:BAD(gene name)|psi-mi:BAD(display_short)|uniprotkb:BBC6(gene name synonym)|uniprotkb:BCL2L8(gene name synonym)|uniprotkb:Bcl-xL/Bcl-2-associated death promoter(gene name synonym)|uniprotkb:Bcl2 antagonist of cell death(gene name synonym) psi-mi:"MI:0096"(pull down) Yasuda et al. (1999) pubmed:9973195|mint:MINT-6594504 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-850652 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204 refseq:NP_004313.1|refseq:NP_116784.1|dip:DIP-29184N|ensembl:ENSG00000002330(gene)|ensembl:ENST00000309032(transcript)|ensembl:ENST00000394532(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006007"(glucose catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008289"(lipid binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033574"(response to testosterone)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046031"(ADP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0071247"(cellular response to chromate)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901423"(response to benzene)|go:"GO:1902220"(positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1904710"(positive regulation of granulosa cell apoptotic process)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR018868|mint:Q92934|rcsb pdb:1G5J|reactome:R-HSA-111447|reactome:R-HSA-111453|reactome:R-HSA-193648|reactome:R-HSA-198323|reactome:R-HSA-5674400 - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/02/10 2014/10/16 rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606 rogid:2c2kSu+3ZHnx458SDbvIcdGV4PA9606 intact-crc:1F9A4DEC7A13F7E2|rigid:Tz/z9XcIgpFfvN1zyb3hQ28ZXzA false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10415 uniprotkb:O60238 intact:EBI-77694|ensembl:ENSP00000329623|ensembl:ENSP00000381185|uniprotkb:P10416|uniprotkb:Q13842|uniprotkb:Q16197|uniprotkb:C9JHD5 intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003 psi-mi:bcl2_human(display_long)|uniprotkb:BCL2(gene name)|psi-mi:BCL2(display_short) psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym) psi-mi:"MI:0096"(pull down) Yasuda et al. (1999) pubmed:9973195|mint:MINT-6594504 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-850662 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020728|interpro:IPR020731|interpro:IPR026298|interpro:IPR036834|rcsb pdb:4LVT|rcsb pdb:4LXD|rcsb pdb:4MAN|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5FCG|rcsb pdb:5JSN|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6GL8|rcsb pdb:6IWB|rcsb pdb:6O0K|rcsb pdb:6O0L|rcsb pdb:6O0M|rcsb pdb:6O0O|rcsb pdb:6O0P|rcsb pdb:7LHB|reactome:R-HSA-111447|reactome:R-HSA-111453|reactome:R-HSA-6785807|reactome:R-HSA-844455|reactome:R-HSA-9018519|reactome:R-HSA-9634638|mint:P10415|rcsb pdb:1G5M|rcsb pdb:1GJH|rcsb pdb:1YSW|rcsb pdb:2O21|rcsb pdb:2O22|rcsb pdb:2O2F|rcsb pdb:2W3L|rcsb pdb:2XA0|rcsb pdb:4AQ3|rcsb pdb:4IEH|go:"GO:0010224"(response to UV-B)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0015267"(channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016248"(channel inhibitor activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|ensembl:ENSG00000171791(gene)|ensembl:ENST00000333681(transcript)|ensembl:ENST00000398117(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0002020"(protease binding)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002931"(response to ischemia)|go:"GO:0031103"(axon regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032835"(glomerulus development)|go:"GO:0032848"(negative regulation of cellular pH reduction)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0034097"(response to cytokine)|go:"GO:0035094"(response to nicotine)|go:"GO:0035265"(organ growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043209"(myelin sheath)|go:"GO:0043375"(CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0003014"(renal system process)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006582"(melanin metabolic process)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007015"(actin filament organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007565"(female pregnancy)|go:"GO:0007569"(cell aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009314"(response to radiation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010039"(response to iron ion)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046930"(pore complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048536"(spleen development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0048538"(thymus development)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048599"(oocyte development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0048753"(pigment granule organization)|go:"GO:0043583"(ear development)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0045636"(positive regulation of melanocyte differentiation)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0046671"(negative regulation of retinal cell programmed cell death)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR004725(Apoptosis regulator Bcl-X protein)|interpro:IPR013278(Apoptosis regulator, Bcl-2)|interpro:IPR020717|interpro:IPR020726|go:"GO:0051924"(regulation of calcium ion transport)|refseq:NP_000624.2|dip:DIP-1043N|refseq:NP_000648.2 refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204 - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/02/10 2014/10/16 rogid:XC215VuR7Wf2ACXOm1pTyyuimSU9606 rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606 intact-crc:6620F166C7A088C9|rigid:BFLIHKYivF4ytq5XRYJQ9I/ACdQ false glutathione s tranferase tag:?-? 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03247 uniprotkb:O60238 intact:EBI-849856 intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003 psi-mi:e1bs_ade02(display_long)|uniprotkb:E1B(gene name)|psi-mi:E1B(display_short)|uniprotkb:E1B 19 kDa protein(gene name synonym)|uniprotkb:E1B-175R(gene name synonym) psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym) psi-mi:"MI:0096"(pull down) Yasuda et al. (1999) pubmed:9973195|mint:MINT-6594504 taxid:10515(ade02)|taxid:10515("Human adenovirus C serotype 2 (HAdV-2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-850682 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002924(Adenovirus small t-antigen, E1B 19 kDa protein)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|refseq:AP_000162.1|refseq:NP_040510.1|go:"GO:0016020"(membrane)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044199"(host cell nuclear envelope)|go:"GO:0044203"(host cell nuclear lamina) refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204 - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/02/10 2014/10/16 rogid:fanyKLOEeRabJxcRQcM87JfsFEk10515 rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606 intact-crc:A965FF8781D5D0C9|rigid:WcJ4ATThvou01Zygsrb3Bv60kSs false glutathione s tranferase tag:?-? 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92934 uniprotkb:O60238 intact:EBI-700771|uniprotkb:O14803|uniprotkb:Q6FH21|ensembl:ENSP00000309103|ensembl:ENSP00000378040 intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003 psi-mi:bad_human(display_long)|uniprotkb:Bcl-2-binding component 6(gene name synonym)|uniprotkb:Bcl-2-like protein 8(gene name synonym)|uniprotkb:BAD(gene name)|psi-mi:BAD(display_short)|uniprotkb:BBC6(gene name synonym)|uniprotkb:BCL2L8(gene name synonym)|uniprotkb:Bcl-xL/Bcl-2-associated death promoter(gene name synonym)|uniprotkb:Bcl2 antagonist of cell death(gene name synonym) psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym) psi-mi:"MI:0096"(pull down) Yasuda et al. (1999) pubmed:9973195|mint:MINT-6594504 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-850691 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004313.1|refseq:NP_116784.1|dip:DIP-29184N|ensembl:ENSG00000002330(gene)|ensembl:ENST00000309032(transcript)|ensembl:ENST00000394532(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006007"(glucose catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008289"(lipid binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033574"(response to testosterone)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046031"(ADP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0071247"(cellular response to chromate)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901423"(response to benzene)|go:"GO:1902220"(positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1904710"(positive regulation of granulosa cell apoptotic process)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR018868|mint:Q92934|rcsb pdb:1G5J|reactome:R-HSA-111447|reactome:R-HSA-111453|reactome:R-HSA-193648|reactome:R-HSA-198323|reactome:R-HSA-5674400 refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204 - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/02/10 2014/10/16 rogid:2c2kSu+3ZHnx458SDbvIcdGV4PA9606 rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606 intact-crc:375335482EAF686A|rigid:Tz/z9XcIgpFfvN1zyb3hQ28ZXzA false glutathione s tranferase tag:?-? sufficient binding region:1-187|35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10415 uniprotkb:O60238 intact:EBI-77694|ensembl:ENSP00000329623|ensembl:ENSP00000381185|uniprotkb:P10416|uniprotkb:Q13842|uniprotkb:Q16197|uniprotkb:C9JHD5 intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003 psi-mi:bcl2_human(display_long)|uniprotkb:BCL2(gene name)|psi-mi:BCL2(display_short) psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym) psi-mi:"MI:0096"(pull down) Yasuda et al. (1999) pubmed:9973195|mint:MINT-6594504 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-850700 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020728|interpro:IPR020731|interpro:IPR026298|interpro:IPR036834|rcsb pdb:4LVT|rcsb pdb:4LXD|rcsb pdb:4MAN|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5FCG|rcsb pdb:5JSN|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6GL8|rcsb pdb:6IWB|rcsb pdb:6O0K|rcsb pdb:6O0L|rcsb pdb:6O0M|rcsb pdb:6O0O|rcsb pdb:6O0P|rcsb pdb:7LHB|reactome:R-HSA-111447|reactome:R-HSA-111453|reactome:R-HSA-6785807|reactome:R-HSA-844455|reactome:R-HSA-9018519|reactome:R-HSA-9634638|mint:P10415|rcsb pdb:1G5M|rcsb pdb:1GJH|rcsb pdb:1YSW|rcsb pdb:2O21|rcsb pdb:2O22|rcsb pdb:2O2F|rcsb pdb:2W3L|rcsb pdb:2XA0|rcsb pdb:4AQ3|rcsb pdb:4IEH|go:"GO:0010224"(response to UV-B)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0015267"(channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016248"(channel inhibitor activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|ensembl:ENSG00000171791(gene)|ensembl:ENST00000333681(transcript)|ensembl:ENST00000398117(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0002020"(protease binding)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002931"(response to ischemia)|go:"GO:0031103"(axon regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032835"(glomerulus development)|go:"GO:0032848"(negative regulation of cellular pH reduction)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0034097"(response to cytokine)|go:"GO:0035094"(response to nicotine)|go:"GO:0035265"(organ growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043209"(myelin sheath)|go:"GO:0043375"(CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0003014"(renal system process)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006582"(melanin metabolic process)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007015"(actin filament organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007565"(female pregnancy)|go:"GO:0007569"(cell aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009314"(response to radiation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010039"(response to iron ion)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046930"(pore complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048536"(spleen development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0048538"(thymus development)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048599"(oocyte development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0048753"(pigment granule organization)|go:"GO:0043583"(ear development)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0045636"(positive regulation of melanocyte differentiation)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0046671"(negative regulation of retinal cell programmed cell death)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR004725(Apoptosis regulator Bcl-X protein)|interpro:IPR013278(Apoptosis regulator, Bcl-2)|interpro:IPR020717|interpro:IPR020726|go:"GO:0051924"(regulation of calcium ion transport)|refseq:NP_000624.2|dip:DIP-1043N|refseq:NP_000648.2 refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204 - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/02/10 2014/10/16 rogid:XC215VuR7Wf2ACXOm1pTyyuimSU9606 rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606 intact-crc:4EE989C2931C1741|rigid:BFLIHKYivF4ytq5XRYJQ9I/ACdQ false glutathione s tranferase tag:?-? 35s radiolabel:?-?|sufficient binding region:1-187 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03247 uniprotkb:O60238 intact:EBI-849856 intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003 psi-mi:e1bs_ade02(display_long)|uniprotkb:E1B(gene name)|psi-mi:E1B(display_short)|uniprotkb:E1B 19 kDa protein(gene name synonym)|uniprotkb:E1B-175R(gene name synonym) psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym) psi-mi:"MI:0096"(pull down) Yasuda et al. (1999) pubmed:9973195|mint:MINT-6594504 taxid:10515(ade02)|taxid:10515("Human adenovirus C serotype 2 (HAdV-2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-850712 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002924(Adenovirus small t-antigen, E1B 19 kDa protein)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|refseq:AP_000162.1|refseq:NP_040510.1|go:"GO:0016020"(membrane)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044199"(host cell nuclear envelope)|go:"GO:0044203"(host cell nuclear lamina) refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204 - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/02/10 2014/10/16 rogid:fanyKLOEeRabJxcRQcM87JfsFEk10515 rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606 intact-crc:81AC8723D5694F41|rigid:WcJ4ATThvou01Zygsrb3Bv60kSs false glutathione s tranferase tag:?-? 35s radiolabel:?-?|sufficient binding region:1-187 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)