#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P52795	uniprotkb:O08992	intact:EBI-8107507|intact:MINT-1793539|ensembl:ENSMUSP00000050716	intact:EBI-538265|uniprotkb:A2AKJ7|uniprotkb:Q544P5|ensembl:ENSMUSP00000029912	psi-mi:efnb1_mouse(display_long)|uniprotkb:Efnb1(gene name)|psi-mi:Efnb1(display_short)|uniprotkb:Epl2(gene name synonym)|uniprotkb:Eplg2(gene name synonym)|uniprotkb:Lerk2(gene name synonym)|uniprotkb:Stra1(gene name synonym)|uniprotkb:EPH-related receptor tyrosine kinase ligand 2(gene name synonym)|uniprotkb:CEK5 receptor ligand(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 1 protein(gene name synonym)|uniprotkb:ELK ligand(gene name synonym)|uniprotkb:EFL-3(gene name synonym)	psi-mi:sdcb1_mouse(display_long)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Sdcbp(gene name)|psi-mi:Sdcbp(display_short)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lin et al. (1999)	pubmed:9920925|mint:MINT-6548509	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8668040|mint:MINT-1793671	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034240.1|dip:DIP-29206N|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034255|mint:P52795|rcsb pdb:6P7S|reactome:R-MMU-2682334|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|go:"GO:0099054"(presynapse assembly)|ensembl:ENSMUSG00000031217(gene)|ensembl:ENSMUST00000052839(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031295"(T cell costimulation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|mint:MINT-1793682(identity)	refseq:NP_001091697.1|refseq:NP_058087.2|refseq:XP_006538147.1|reactome:R-MMU-5213460|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-447043|ensembl:ENSMUSG00000028249(gene)|ensembl:ENSMUST00000029912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|mint:O08992|reactome:R-MMU-3928664|mint:MINT-1793672(identity)	-	function:Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5B|kinetics:kd 17.7 micromolar|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/30	2014/10/16	rogid:Js3TO3daJCJdawFl8NX7HMgbpkM10090	rogid:/hMRO9ZA+m3lU6+RgIvyEr/a1+w10090	intact-crc:9F833A9E795387DA|rigid:omSwI3xqTNW2YBkc/cW+2QmMJUE	false	binding-associated region:340-345(MINT-1793693)|tag:?-?(MINT-1793697)	glutathione s tranferase tag:?-?(MINT-1793680)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52795	uniprotkb:Q64512	intact:EBI-8107507|intact:MINT-1793539|ensembl:ENSMUSP00000050716	intact:EBI-4284057|uniprotkb:Q61494|uniprotkb:Q62135|uniprotkb:Q64499	psi-mi:efnb1_mouse(display_long)|uniprotkb:Efnb1(gene name)|psi-mi:Efnb1(display_short)|uniprotkb:Epl2(gene name synonym)|uniprotkb:Eplg2(gene name synonym)|uniprotkb:Lerk2(gene name synonym)|uniprotkb:Stra1(gene name synonym)|uniprotkb:EPH-related receptor tyrosine kinase ligand 2(gene name synonym)|uniprotkb:CEK5 receptor ligand(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 1 protein(gene name synonym)|uniprotkb:ELK ligand(gene name synonym)|uniprotkb:EFL-3(gene name synonym)	psi-mi:ptn13_mouse(display_long)|uniprotkb:Ptpn13(gene name)|psi-mi:Ptpn13(display_short)|uniprotkb:Ptp14(gene name synonym)|uniprotkb:PTP36(gene name synonym)|uniprotkb:Protein tyrosine phosphatase DPZPTP(gene name synonym)|uniprotkb:Protein tyrosine phosphatase PTP-BL(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase RIP(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lin et al. (1999)	pubmed:9920925|mint:MINT-6548509	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8668062|mint:MINT-1793703	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034240.1|dip:DIP-29206N|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034255|mint:P52795|rcsb pdb:6P7S|reactome:R-MMU-2682334|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|go:"GO:0099054"(presynapse assembly)|ensembl:ENSMUSG00000031217(gene)|ensembl:ENSMUST00000052839(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031295"(T cell costimulation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|mint:MINT-1793704(identity)	interpro:IPR035963|interpro:IPR036034|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|rcsb pdb:6GBD|rcsb pdb:6GBE|refseq:NP_035334.2|interpro:IPR019749|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR018980|interpro:IPR011019(KIND)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|rcsb pdb:1GM1|rcsb pdb:1OZI|rcsb pdb:1VJ6|interpro:IPR029021|interpro:IPR029071|go:"GO:0001650"(fibrillar center)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0030496"(midbody)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|reactome:R-MMU-1660499|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273|mint:MINT-1793713(identity)	-	function:Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5A|kinetics:kd 9.9 micromolar|comment:domino|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/30	2014/10/16	rogid:Js3TO3daJCJdawFl8NX7HMgbpkM10090	rogid:cPfYanrHD/RnZ+Akt306Ua1CQxI10090	intact-crc:E0255EB1E1E1B2B9|rigid:nTqF9FLuf/qgQ2mRfeNtiqeKVsU	false	binding-associated region:340-345(MINT-1793705)	binding-associated region:1859-1939(MINT-1793721)|glutathione s tranferase tag:?-?(MINT-1793718)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52795	uniprotkb:O08992	intact:EBI-8107507|intact:MINT-1793539|ensembl:ENSMUSP00000050716	intact:EBI-538265|uniprotkb:A2AKJ7|uniprotkb:Q544P5|ensembl:ENSMUSP00000029912	psi-mi:efnb1_mouse(display_long)|uniprotkb:Efnb1(gene name)|psi-mi:Efnb1(display_short)|uniprotkb:Epl2(gene name synonym)|uniprotkb:Eplg2(gene name synonym)|uniprotkb:Lerk2(gene name synonym)|uniprotkb:Stra1(gene name synonym)|uniprotkb:EPH-related receptor tyrosine kinase ligand 2(gene name synonym)|uniprotkb:CEK5 receptor ligand(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 1 protein(gene name synonym)|uniprotkb:ELK ligand(gene name synonym)|uniprotkb:EFL-3(gene name synonym)	psi-mi:sdcb1_mouse(display_long)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Sdcbp(gene name)|psi-mi:Sdcbp(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lin et al. (1999)	pubmed:9920925|mint:MINT-6548509	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8668094|mint:MINT-1793729	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034240.1|dip:DIP-29206N|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034255|mint:P52795|rcsb pdb:6P7S|reactome:R-MMU-2682334|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|go:"GO:0099054"(presynapse assembly)|ensembl:ENSMUSG00000031217(gene)|ensembl:ENSMUST00000052839(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031295"(T cell costimulation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|mint:MINT-1793740(identity)	refseq:NP_001091697.1|refseq:NP_058087.2|refseq:XP_006538147.1|reactome:R-MMU-5213460|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-447043|ensembl:ENSMUSG00000028249(gene)|ensembl:ENSMUST00000029912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|mint:O08992|reactome:R-MMU-3928664|mint:MINT-1793730(identity)	-	function:Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F6|comment:homomint|comment:mint	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/03/30	2014/10/16	rogid:Js3TO3daJCJdawFl8NX7HMgbpkM10090	rogid:/hMRO9ZA+m3lU6+RgIvyEr/a1+w10090	intact-crc:BACAE20D89AC8B14|rigid:omSwI3xqTNW2YBkc/cW+2QmMJUE	false	-	flag tag:n-n(MINT-1793738)	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52795	uniprotkb:O08992	intact:EBI-8107507|intact:MINT-1793539|ensembl:ENSMUSP00000050716	intact:EBI-538265|uniprotkb:A2AKJ7|uniprotkb:Q544P5|ensembl:ENSMUSP00000029912	psi-mi:efnb1_mouse(display_long)|uniprotkb:Efnb1(gene name)|psi-mi:Efnb1(display_short)|uniprotkb:Epl2(gene name synonym)|uniprotkb:Eplg2(gene name synonym)|uniprotkb:Lerk2(gene name synonym)|uniprotkb:Stra1(gene name synonym)|uniprotkb:EPH-related receptor tyrosine kinase ligand 2(gene name synonym)|uniprotkb:CEK5 receptor ligand(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 1 protein(gene name synonym)|uniprotkb:ELK ligand(gene name synonym)|uniprotkb:EFL-3(gene name synonym)	psi-mi:sdcb1_mouse(display_long)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Sdcbp(gene name)|psi-mi:Sdcbp(display_short)	psi-mi:"MI:0096"(pull down)	Lin et al. (1999)	pubmed:9920925|mint:MINT-6548509	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8668116|mint:MINT-1793646	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034240.1|dip:DIP-29206N|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034255|mint:P52795|rcsb pdb:6P7S|reactome:R-MMU-2682334|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|go:"GO:0099054"(presynapse assembly)|ensembl:ENSMUSG00000031217(gene)|ensembl:ENSMUST00000052839(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031295"(T cell costimulation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|mint:MINT-1793654(identity)	refseq:NP_001091697.1|refseq:NP_058087.2|refseq:XP_006538147.1|reactome:R-MMU-5213460|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-447043|ensembl:ENSMUSG00000028249(gene)|ensembl:ENSMUST00000029912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|mint:O08992|reactome:R-MMU-3928664|mint:MINT-1793647(identity)	-	function:Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4B|figure legend:F3D|comment:homomint|comment:domino|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/30	2014/10/16	rogid:Js3TO3daJCJdawFl8NX7HMgbpkM10090	rogid:/hMRO9ZA+m3lU6+RgIvyEr/a1+w10090	intact-crc:67765ADB505627FD|rigid:omSwI3xqTNW2YBkc/cW+2QmMJUE	false	mutation disrupting interaction:345-345(MINT-1795283)	glutathione s tranferase tag:?-?(MINT-1793648)|binding-associated region:172-299(MINT-1793667)	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O35393	uniprotkb:O08992	intact:EBI-8668154|ensembl:ENSMUSP00000004036|intact:MINT-1793420	intact:EBI-538265|uniprotkb:A2AKJ7|uniprotkb:Q544P5|ensembl:ENSMUSP00000029912	psi-mi:efnb3_mouse(display_long)|uniprotkb:Efnb3(gene name)|psi-mi:Efnb3(display_short)	psi-mi:sdcb1_mouse(display_long)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Sdcbp(gene name)|psi-mi:Sdcbp(display_short)	psi-mi:"MI:0066"(lambda phage display)	Lin et al. (1999)	pubmed:9920925|mint:MINT-6548509	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8668149|mint:MINT-1793489	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099557"(trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|rcsb pdb:3D12|reactome:R-MMU-2682334|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|ensembl:ENSMUSG00000003934(gene)|ensembl:ENSMUST00000004036(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0007628"(adult walking behavior)|go:"GO:0016198"(axon choice point recognition)|go:"GO:0031295"(T cell costimulation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|refseq:NP_031937.1|dip:DIP-44833N|mint:MINT-1793501(identity)	refseq:NP_001091697.1|refseq:NP_058087.2|refseq:XP_006538147.1|reactome:R-MMU-5213460|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-447043|ensembl:ENSMUSG00000028249(gene)|ensembl:ENSMUST00000029912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|mint:O08992|reactome:R-MMU-3928664|mint:MINT-1793490(identity)	-	comment:mint|function:May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/30	2014/10/16	rogid:3ZWgTbbk1ZmcfAurzBW7XhWOkc010090	rogid:/hMRO9ZA+m3lU6+RgIvyEr/a1+w10090	intact-crc:EAEF506ED60AE0DB|rigid:6LAzhPcNAqvlV0+/7MTFkQun1Dc	false	binding-associated region:329-340(MINT-1793509)|biotin tag:?-?(MINT-1793502)	fusion protein:?-?(MINT-1793499)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O35393	uniprotkb:Q99NH2	intact:EBI-8668154|ensembl:ENSMUSP00000004036|intact:MINT-1793420	intact:EBI-6299697|uniprotkb:Q58T10|uniprotkb:Q58T11|uniprotkb:Q8CB21	psi-mi:efnb3_mouse(display_long)|uniprotkb:Efnb3(gene name)|psi-mi:Efnb3(display_short)	psi-mi:pard3_mouse(display_long)|uniprotkb:Pard3(gene name)|psi-mi:Pard3(display_short)|uniprotkb:Par3(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:Ephrin-interacting protein(gene name synonym)	psi-mi:"MI:0066"(lambda phage display)	Lin et al. (1999)	pubmed:9920925|mint:MINT-6548509	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8668188|mint:MINT-1793437	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099557"(trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|rcsb pdb:3D12|reactome:R-MMU-2682334|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|ensembl:ENSMUSG00000003934(gene)|ensembl:ENSMUST00000004036(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0007628"(adult walking behavior)|go:"GO:0016198"(axon choice point recognition)|go:"GO:0031295"(T cell costimulation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|refseq:NP_031937.1|dip:DIP-44833N|mint:MINT-1793438(identity)	refseq:NP_001013598.1|refseq:NP_001013599.1|go:"GO:0008104"(protein localization)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|rcsb pdb:2KOH|rcsb pdb:2KOJ|reactome:R-MMU-2173791|reactome:R-MMU-420029|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003383"(apical constriction)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|dip:DIP-41727N|mint:Q99NH2|mint:MINT-1793439(identity)	-	comment:mint|function:May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:domino|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/30	2014/10/16	rogid:3ZWgTbbk1ZmcfAurzBW7XhWOkc010090	rogid:T32+accBUmq14vv2OXj2mZe9fzQ10090	intact-crc:F00782046D4D7B66|rigid:L7FObGVWLSNzZgEJBLwCbSb7YZk	false	biotin tag:?-?(MINT-1793444)|binding-associated region:329-340(MINT-1793451)	binding-associated region:461-731(MINT-1793461)|fusion protein:?-?(MINT-1793454)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O35393	uniprotkb:Q925T6	intact:EBI-8668154|ensembl:ENSMUSP00000004036|intact:MINT-1793420	intact:EBI-537752|uniprotkb:Q8BLQ3|uniprotkb:Q8C0T3|uniprotkb:Q925T5|uniprotkb:Q925T7|ensembl:ENSMUSP00000123234	psi-mi:efnb3_mouse(display_long)|uniprotkb:Efnb3(gene name)|psi-mi:Efnb3(display_short)	psi-mi:grip1_mouse(display_long)|uniprotkb:Grip1(gene name)|psi-mi:Grip1(display_short)	psi-mi:"MI:0066"(lambda phage display)	Lin et al. (1999)	pubmed:9920925|mint:MINT-6548509	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8668215|mint:MINT-1793465	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099557"(trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|rcsb pdb:3D12|reactome:R-MMU-2682334|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|ensembl:ENSMUSG00000003934(gene)|ensembl:ENSMUST00000004036(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0007628"(adult walking behavior)|go:"GO:0016198"(axon choice point recognition)|go:"GO:0031295"(T cell costimulation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|refseq:NP_031937.1|dip:DIP-44833N|mint:MINT-1793477(identity)	refseq:NP_001264224.1|refseq:NP_083012.1|refseq:NP_570961.1|refseq:NP_597699.1|refseq:NP_001264221.1|refseq:NP_001264223.1|ensembl:ENSMUSG00000034813(gene)|ensembl:ENSMUST00000138410(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030026|interpro:IPR036034|interpro:IPR041489|interpro:IPR043545|mint:Q925T6|rcsb pdb:1V5Q|reactome:R-MMU-416993|mint:MINT-1793466(identity)	-	comment:mint|function:May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:homomint|comment:domino|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/30	2014/10/16	rogid:3ZWgTbbk1ZmcfAurzBW7XhWOkc010090	rogid:nQDCS/yQb0DlZs+60Vf3Q3hbECk10090	intact-crc:E40FBCAFF680C20B|rigid:nG9kBeiFJ3ojIBAxdTqDcdAgAl4	false	binding-associated region:329-340(MINT-1793478)|biotin tag:?-?(MINT-1793485)	binding-associated region:642-1112(MINT-1793467)|fusion protein:?-?(MINT-1793475)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)