#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P84077	uniprotkb:Q9QWY8	intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102|ensembl:ENSP00000440005|ensembl:ENSP00000442980	intact:EBI-698498|uniprotkb:Q99LV8|uniprotkb:Q9Z2B6|uniprotkb:O08612|uniprotkb:Q80TG8|uniprotkb:Q80UV6|uniprotkb:Q505F0|ensembl:ENSMUSP00000134825	psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)	psi-mi:asap1_mouse(display_long)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:Asap1(gene name)|psi-mi:Asap1(display_short)|uniprotkb:Ddef1(gene name synonym)|uniprotkb:Kiaa1249(gene name synonym)|uniprotkb:Shag1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Brown et al. (1998)	pubmed:9819391|imex:IM-19368	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-847993|imex:IM-19368-1	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N|ensembl:ENSG00000143761(gene)|ensembl:ENST00000272102(transcript)|ensembl:ENST00000540651(transcript)|ensembl:ENST00000541182(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7MGE|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505	refseq:NP_001263396.1|refseq:NP_034156.2|refseq:NP_001263390.1|refseq:NP_001263391.1|ensembl:ENSMUSG00000022377(gene)|ensembl:ENSMUST00000177374(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9QWY8|rcsb pdb:5C6R|rcsb pdb:5C79|reactome:R-MMU-5620916	go:"GO:0005096"(GTPase activator activity)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/06	2014/10/16	rogid:zray9asm6VonxpuJpv0dRBspPt89606	rogid:/jhMt+/t+DTqI3ZQmzU0IMFCHdA10090	intact-crc:6100B80FC16686B8|rigid:xWLrp6z/EWy8sXgXDKxyEi5OAK8	false	-	sufficient binding region:325-724(IPR001164)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P84077	uniprotkb:Q9QWY8-2	intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102|ensembl:ENSP00000440005|ensembl:ENSP00000442980	intact:EBI-698524|ensembl:ENSMUSP00000135190	psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)	psi-mi:q9qwy8-2(display_long)|uniprotkb:SHAG1b(isoform synonym)|uniprotkb:ASAP1b(isoform synonym)|uniprotkb:Asap1(gene name)|psi-mi:Asap1(display_short)|uniprotkb:Ddef1(gene name synonym)|uniprotkb:Kiaa1249(gene name synonym)|uniprotkb:Shag1(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Brown et al. (1998)	pubmed:9819391|imex:IM-19368	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848003|imex:IM-19368-2	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N|ensembl:ENSG00000143761(gene)|ensembl:ENST00000272102(transcript)|ensembl:ENST00000540651(transcript)|ensembl:ENST00000541182(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7MGE|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505	intact:EBI-698498(ddef1_mouse)|ensembl:ENSMUSG00000022377(gene)|ensembl:ENSMUST00000176384(transcript)	go:"GO:0005096"(GTPase activator activity)	-	-	comment:Increased activity of Arf1 GAp activity in lysates of cells overexpressing ASAP1b.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/06	2014/10/16	rogid:zray9asm6VonxpuJpv0dRBspPt89606	rogid:yPJrj4jSikLFp4R3miQOPDyXrRs10090	intact-crc:4E40F98B3C0AB374|rigid:W1+Mw2YxDkzoprDgX4cnM8PR4vE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P84077	uniprotkb:O97902	intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102|ensembl:ENSP00000440005|ensembl:ENSP00000442980	intact:EBI-848008	psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)	psi-mi:asap1_bovin(display_long)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Brown et al. (1998)	pubmed:9819391|imex:IM-19368	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848021|imex:IM-19368-3	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N|ensembl:ENSG00000143761(gene)|ensembl:ENST00000272102(transcript)|ensembl:ENST00000540651(transcript)|ensembl:ENST00000541182(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7MGE|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505	interpro:IPR027267|refseq:NP_787015.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036770|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR037278|interpro:IPR043593|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)	go:"GO:0005096"(GTPase activator activity)	-	-	comment:Bovin endogenous ASAP1 is purified to homogeneity from bovin brain|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/06	2014/10/16	rogid:zray9asm6VonxpuJpv0dRBspPt89606	rogid:4mc33mmUUJpQlwmnLTradybPIdM9913	intact-crc:8FC0DB011EF9C91C|rigid:pEXtnrNj6/DhP3D0EGuRWBN2Rvo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00523	uniprotkb:Q9QWY8-1	intact:EBI-848039|uniprotkb:Q90992|uniprotkb:Q90993|uniprotkb:Q91343|uniprotkb:Q91345|uniprotkb:Q92013|uniprotkb:Q98915|ensembl:ENSGALP00000049896|ensembl:ENSGALP00000054990|ensembl:ENSGALP00000068298	intact:EBI-698517|ensembl:ENSMUSP00000134825	psi-mi:src_chick(display_long)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:q9qwy8-1(display_long)|uniprotkb:SHAG1a(isoform synonym)|uniprotkb:ASAP1a(isoform synonym)|uniprotkb:Kiaa1249(gene name synonym)|uniprotkb:Shag1(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:Asap1(gene name)|psi-mi:Asap1(display_short)|uniprotkb:Ddef1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Brown et al. (1998)	pubmed:9819391|imex:IM-19368	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848034|imex:IM-19368-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_990788.2|dip:DIP-449N|refseq:XP_015151834.1|ensembl:ENSGALG00000003855(gene)|ensembl:ENSGALT00000061823(transcript)|ensembl:ENSGALT00000070498(transcript)|ensembl:ENSGALT00000093274(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020037"(heme binding)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036035"(osteoclast development)|go:"GO:0045087"(innate immune response)|go:"GO:0045453"(bone resorption)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071253"(connexin binding)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P00523|rcsb pdb:1F1W|rcsb pdb:1F2F|rcsb pdb:1NLO|rcsb pdb:1NLP|rcsb pdb:1P13|rcsb pdb:1PRL|rcsb pdb:1PRM|rcsb pdb:1RLP|rcsb pdb:1RLQ|rcsb pdb:1SRL|rcsb pdb:1SRM|rcsb pdb:2HWO|rcsb pdb:2HWP|rcsb pdb:2OIQ|rcsb pdb:2PTK|rcsb pdb:2QI8|rcsb pdb:2QLQ|rcsb pdb:2QQ7|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3DQW|rcsb pdb:3DQX|rcsb pdb:3EL7|rcsb pdb:3EL8|rcsb pdb:3EN4|rcsb pdb:3EN5|rcsb pdb:3EN6|rcsb pdb:3EN7|rcsb pdb:3F3T|rcsb pdb:3F3U|rcsb pdb:3F3V|rcsb pdb:3F3W|rcsb pdb:3F6X|rcsb pdb:3FJ5|rcsb pdb:3G5D|rcsb pdb:3G6G|rcsb pdb:3G6H|rcsb pdb:3GEQ|rcsb pdb:3LOK|rcsb pdb:3OEZ|rcsb pdb:3OF0|rcsb pdb:3QLF|rcsb pdb:3QLG|rcsb pdb:3SVV|rcsb pdb:3TZ7|rcsb pdb:3TZ8|rcsb pdb:3TZ9|rcsb pdb:3U4W|rcsb pdb:3U51|rcsb pdb:3UQF|rcsb pdb:3UQG|rcsb pdb:4AGW|rcsb pdb:4DGG|rcsb pdb:4FIC|rcsb pdb:4HVU|rcsb pdb:4HVV|rcsb pdb:4HVW|rcsb pdb:4JZ3|rcsb pdb:4JZ4|rcsb pdb:4LE9|rcsb pdb:4LGG|rcsb pdb:4LGH|rcsb pdb:4MCV|rcsb pdb:4O2P|rcsb pdb:4OML|rcsb pdb:4OMM|rcsb pdb:4OMN|rcsb pdb:4OMO|rcsb pdb:4OMP|rcsb pdb:4OMQ|rcsb pdb:4QT7|rcsb pdb:4RTU|rcsb pdb:4RTV|rcsb pdb:4RTW|rcsb pdb:4RTX|rcsb pdb:4RTY|rcsb pdb:4RTZ|rcsb pdb:4U5J|rcsb pdb:4YBJ|rcsb pdb:4YBK|rcsb pdb:5BMM|rcsb pdb:5D10|rcsb pdb:5D11|rcsb pdb:5D12|rcsb pdb:5EC7|rcsb pdb:5ECA|rcsb pdb:5I11|rcsb pdb:5J5S|rcsb pdb:5K9I|rcsb pdb:5OAV|rcsb pdb:5OB0|rcsb pdb:5OB1|rcsb pdb:5OB2|rcsb pdb:5SWH|rcsb pdb:5SYS|rcsb pdb:5T0P|rcsb pdb:5TEH|rcsb pdb:5XP5|rcsb pdb:5XP7|rcsb pdb:6HVE|rcsb pdb:6HVF|rcsb pdb:6L8L|rcsb pdb:6WIW|rcsb pdb:6XVM|rcsb pdb:6XVN|rcsb pdb:6XVO|rcsb pdb:6XX2|rcsb pdb:6XX3|rcsb pdb:6XX4|rcsb pdb:6XX5|reactome:R-GGA-1227986|reactome:R-GGA-1251985|reactome:R-GGA-1253288|reactome:R-GGA-1257604|reactome:R-GGA-1433557|reactome:R-GGA-180292|reactome:R-GGA-186763|reactome:R-GGA-191650|reactome:R-GGA-2029481|reactome:R-GGA-210990|reactome:R-GGA-354192|reactome:R-GGA-354194|reactome:R-GGA-372708|reactome:R-GGA-389356|reactome:R-GGA-389513|reactome:R-GGA-3928662|reactome:R-GGA-3928663|reactome:R-GGA-3928664|reactome:R-GGA-3928665|reactome:R-GGA-418592|reactome:R-GGA-418594|reactome:R-GGA-418885|reactome:R-GGA-430116|reactome:R-GGA-437239|reactome:R-GGA-4420097|reactome:R-GGA-456926|reactome:R-GGA-5218921|reactome:R-GGA-5674135|reactome:R-GGA-6811558|reactome:R-GGA-8853659|reactome:R-GGA-8874081|reactome:R-GGA-8941858|reactome:R-GGA-9009391	intact:EBI-698498(ddef1_mouse)|ensembl:ENSMUSG00000022377(gene)|ensembl:ENSMUST00000177374(transcript)	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/02/06	2014/10/16	rogid:4zMmRUOi44prLCXBJNuTuFIMkr49031	rogid:/jhMt+/t+DTqI3ZQmzU0IMFCHdA10090	intact-crc:C358F97CBA706854|rigid:wjKo/5tc64eZ05Pc5AARPF39fZk	false	sufficient binding region:82-145(IPR001452)	sufficient binding region:697-850	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9QWY8-1	uniprotkb:P00523	intact:EBI-698517|ensembl:ENSMUSP00000134825	intact:EBI-848039|uniprotkb:Q90992|uniprotkb:Q90993|uniprotkb:Q91343|uniprotkb:Q91345|uniprotkb:Q92013|uniprotkb:Q98915|ensembl:ENSGALP00000049896|ensembl:ENSGALP00000054990|ensembl:ENSGALP00000068298	psi-mi:q9qwy8-1(display_long)|uniprotkb:SHAG1a(isoform synonym)|uniprotkb:ASAP1a(isoform synonym)|uniprotkb:Kiaa1249(gene name synonym)|uniprotkb:Shag1(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:Asap1(gene name)|psi-mi:Asap1(display_short)|uniprotkb:Ddef1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:src_chick(display_long)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:"MI:0096"(pull down)	Brown et al. (1998)	pubmed:9819391|imex:IM-19368	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848075|imex:IM-19368-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-698498(ddef1_mouse)|ensembl:ENSMUSG00000022377(gene)|ensembl:ENSMUST00000177374(transcript)	refseq:NP_990788.2|dip:DIP-449N|refseq:XP_015151834.1|ensembl:ENSGALG00000003855(gene)|ensembl:ENSGALT00000061823(transcript)|ensembl:ENSGALT00000070498(transcript)|ensembl:ENSGALT00000093274(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020037"(heme binding)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036035"(osteoclast development)|go:"GO:0045087"(innate immune response)|go:"GO:0045453"(bone resorption)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071253"(connexin binding)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P00523|rcsb pdb:1F1W|rcsb pdb:1F2F|rcsb pdb:1NLO|rcsb pdb:1NLP|rcsb pdb:1P13|rcsb pdb:1PRL|rcsb pdb:1PRM|rcsb pdb:1RLP|rcsb pdb:1RLQ|rcsb pdb:1SRL|rcsb pdb:1SRM|rcsb pdb:2HWO|rcsb pdb:2HWP|rcsb pdb:2OIQ|rcsb pdb:2PTK|rcsb pdb:2QI8|rcsb pdb:2QLQ|rcsb pdb:2QQ7|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3DQW|rcsb pdb:3DQX|rcsb pdb:3EL7|rcsb pdb:3EL8|rcsb pdb:3EN4|rcsb pdb:3EN5|rcsb pdb:3EN6|rcsb pdb:3EN7|rcsb pdb:3F3T|rcsb pdb:3F3U|rcsb pdb:3F3V|rcsb pdb:3F3W|rcsb pdb:3F6X|rcsb pdb:3FJ5|rcsb pdb:3G5D|rcsb pdb:3G6G|rcsb pdb:3G6H|rcsb pdb:3GEQ|rcsb pdb:3LOK|rcsb pdb:3OEZ|rcsb pdb:3OF0|rcsb pdb:3QLF|rcsb pdb:3QLG|rcsb pdb:3SVV|rcsb pdb:3TZ7|rcsb pdb:3TZ8|rcsb pdb:3TZ9|rcsb pdb:3U4W|rcsb pdb:3U51|rcsb pdb:3UQF|rcsb pdb:3UQG|rcsb pdb:4AGW|rcsb pdb:4DGG|rcsb pdb:4FIC|rcsb pdb:4HVU|rcsb pdb:4HVV|rcsb pdb:4HVW|rcsb pdb:4JZ3|rcsb pdb:4JZ4|rcsb pdb:4LE9|rcsb pdb:4LGG|rcsb pdb:4LGH|rcsb pdb:4MCV|rcsb pdb:4O2P|rcsb pdb:4OML|rcsb pdb:4OMM|rcsb pdb:4OMN|rcsb pdb:4OMO|rcsb pdb:4OMP|rcsb pdb:4OMQ|rcsb pdb:4QT7|rcsb pdb:4RTU|rcsb pdb:4RTV|rcsb pdb:4RTW|rcsb pdb:4RTX|rcsb pdb:4RTY|rcsb pdb:4RTZ|rcsb pdb:4U5J|rcsb pdb:4YBJ|rcsb pdb:4YBK|rcsb pdb:5BMM|rcsb pdb:5D10|rcsb pdb:5D11|rcsb pdb:5D12|rcsb pdb:5EC7|rcsb pdb:5ECA|rcsb pdb:5I11|rcsb pdb:5J5S|rcsb pdb:5K9I|rcsb pdb:5OAV|rcsb pdb:5OB0|rcsb pdb:5OB1|rcsb pdb:5OB2|rcsb pdb:5SWH|rcsb pdb:5SYS|rcsb pdb:5T0P|rcsb pdb:5TEH|rcsb pdb:5XP5|rcsb pdb:5XP7|rcsb pdb:6HVE|rcsb pdb:6HVF|rcsb pdb:6L8L|rcsb pdb:6WIW|rcsb pdb:6XVM|rcsb pdb:6XVN|rcsb pdb:6XVO|rcsb pdb:6XX2|rcsb pdb:6XX3|rcsb pdb:6XX4|rcsb pdb:6XX5|reactome:R-GGA-1227986|reactome:R-GGA-1251985|reactome:R-GGA-1253288|reactome:R-GGA-1257604|reactome:R-GGA-1433557|reactome:R-GGA-180292|reactome:R-GGA-186763|reactome:R-GGA-191650|reactome:R-GGA-2029481|reactome:R-GGA-210990|reactome:R-GGA-354192|reactome:R-GGA-354194|reactome:R-GGA-372708|reactome:R-GGA-389356|reactome:R-GGA-389513|reactome:R-GGA-3928662|reactome:R-GGA-3928663|reactome:R-GGA-3928664|reactome:R-GGA-3928665|reactome:R-GGA-418592|reactome:R-GGA-418594|reactome:R-GGA-418885|reactome:R-GGA-430116|reactome:R-GGA-437239|reactome:R-GGA-4420097|reactome:R-GGA-456926|reactome:R-GGA-5218921|reactome:R-GGA-5674135|reactome:R-GGA-6811558|reactome:R-GGA-8853659|reactome:R-GGA-8874081|reactome:R-GGA-8941858|reactome:R-GGA-9009391	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/06	2014/10/16	rogid:/jhMt+/t+DTqI3ZQmzU0IMFCHdA10090	rogid:4zMmRUOi44prLCXBJNuTuFIMkr49031	intact-crc:5267DD3A942F5334|rigid:wjKo/5tc64eZ05Pc5AARPF39fZk	false	sufficient binding region:697-850|35s radiolabel:?-?	sufficient binding region:82-145|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06241	uniprotkb:Q9QWY8-1	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671|ensembl:ENSP00000357656	intact:EBI-698517|ensembl:ENSMUSP00000134825	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:q9qwy8-1(display_long)|uniprotkb:SHAG1a(isoform synonym)|uniprotkb:ASAP1a(isoform synonym)|uniprotkb:Kiaa1249(gene name synonym)|uniprotkb:Shag1(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:Asap1(gene name)|psi-mi:Asap1(display_short)|uniprotkb:Ddef1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Brown et al. (1998)	pubmed:9819391|imex:IM-19368	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848087|imex:IM-19368-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|dip:DIP-33876N|ensembl:ENSG00000010810(gene)|ensembl:ENST00000354650(transcript)|ensembl:ENST00000368667(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001764"(neuron migration)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0003015"(heart process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007612"(learning)|go:"GO:0007631"(feeding behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|interpro:IPR036028|interpro:IPR036860|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9670439	intact:EBI-698498(ddef1_mouse)|ensembl:ENSMUSG00000022377(gene)|ensembl:ENSMUST00000177374(transcript)	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/06	2014/10/16	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	rogid:/jhMt+/t+DTqI3ZQmzU0IMFCHdA10090	intact-crc:88882A5A15B03DD2|rigid:N2spvHV2QTVdhGGVFABM5/bYmsM	false	sufficient binding region:82..82-143..143(IPR001452)|glutathione s tranferase tag:?-?	sufficient binding region:697-850|35s radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9QWY8-1	uniprotkb:P07948	intact:EBI-698517|ensembl:ENSMUSP00000134825	intact:EBI-79452|ensembl:ENSP00000428924|uniprotkb:A0AVQ5|intact:EBI-6868890	psi-mi:q9qwy8-1(display_long)|uniprotkb:SHAG1a(isoform synonym)|uniprotkb:ASAP1a(isoform synonym)|uniprotkb:Kiaa1249(gene name synonym)|uniprotkb:Shag1(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:Asap1(gene name)|psi-mi:Asap1(display_short)|uniprotkb:Ddef1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:lyn_human(display_long)|uniprotkb:JTK8(gene name synonym)|uniprotkb:Lck/Yes-related novel protein tyrosine kinase(gene name synonym)|uniprotkb:V-yes-1 Yamaguchi sarcoma viral related oncogene homolog(gene name synonym)|uniprotkb:p53Lyn(gene name synonym)|uniprotkb:p56Lyn(gene name synonym)|uniprotkb:LYN(gene name)|psi-mi:LYN(display_short)	psi-mi:"MI:0096"(pull down)	Brown et al. (1998)	pubmed:9819391|imex:IM-19368	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848100|imex:IM-19368-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-698498(ddef1_mouse)|ensembl:ENSMUSG00000022377(gene)|ensembl:ENSMUST00000177374(transcript)	refseq:NP_001104567.1|refseq:NP_002341.1|ensembl:ENSG00000254087(gene)|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-983695|reactome:R-HSA-9664323|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002431"(Fc receptor mediated stimulatory signaling pathway)|go:"GO:0002513"(tolerance induction to self antigen)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0002576"(platelet degranulation)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0002768"(immune response-regulating cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002902"(regulation of B cell apoptotic process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|ensembl:ENST00000519728(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006991"(response to sterol depletion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009725"(response to hormone)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016301"(kinase activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032868"(response to insulin)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043200"(response to amino acid)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050855"(regulation of B cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060369"(positive regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070304"(positive regulation of stress-activated protein kinase signaling cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070447"(positive regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070667"(negative regulation of mast cell proliferation)|go:"GO:0070668"(positive regulation of mast cell proliferation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0090025"(regulation of monocyte chemotaxis)|go:"GO:0090330"(regulation of platelet aggregation)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1902532"(negative regulation of intracellular signal transduction)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:2000670"(positive regulation of dendritic cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035748|interpro:IPR035852|interpro:IPR036028|interpro:IPR036860|mint:P07948|rcsb pdb:1W1F|rcsb pdb:1WA7|go:"GO:0099091"(postsynaptic specialization, intracellular component)|rcsb pdb:5XY1|rcsb pdb:6NMW|reactome:R-HSA-114604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2454202|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-389356|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-5621480|rcsb pdb:3A4O|reactome:R-HSA-5621575|reactome:R-HSA-5690714|reactome:R-HSA-69231|reactome:R-HSA-75892|reactome:R-HSA-9006335|reactome:R-HSA-9027276|reactome:R-HSA-9027277|reactome:R-HSA-9027283|reactome:R-HSA-9027284|reactome:R-HSA-912631|refseq:XP_016868905.1|dip:DIP-1056N	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/06	2014/10/16	rogid:/jhMt+/t+DTqI3ZQmzU0IMFCHdA10090	rogid:SqXPSC+g2ZuGHy6TAPV4HcpXe6U9606	intact-crc:693EFB949535A918|rigid:XpQKBP9Vs9BmcFvI0RhQEJ/uR+k	false	35s radiolabel:?-?|sufficient binding region:697-850	sufficient binding region:63-123(IPR001452)|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9QWY8-2	uniprotkb:P46108	intact:EBI-698524|ensembl:ENSMUSP00000135190	intact:EBI-886|uniprotkb:B0LPE8|uniprotkb:Q96HJ0|uniprotkb:A8MWE8|uniprotkb:Q96GA9|uniprotkb:D3DTH6|intact:EBI-28974221|ensembl:ENSP00000300574|intact:EBI-16429791	psi-mi:q9qwy8-2(display_long)|uniprotkb:SHAG1b(isoform synonym)|uniprotkb:ASAP1b(isoform synonym)|uniprotkb:Asap1(gene name)|psi-mi:Asap1(display_short)|uniprotkb:Ddef1(gene name synonym)|uniprotkb:Kiaa1249(gene name synonym)|uniprotkb:Shag1(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:crk_human(display_long)|uniprotkb:Proto-oncogene c-Crk(gene name synonym)|uniprotkb:CRK(gene name)|psi-mi:CRK(display_short)|uniprotkb:p38(gene name synonym)	psi-mi:"MI:0096"(pull down)	Brown et al. (1998)	pubmed:9819391|imex:IM-19368	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848113|imex:IM-19368-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-698498(ddef1_mouse)|ensembl:ENSMUSG00000022377(gene)|ensembl:ENSMUST00000176384(transcript)	ensembl:ENSP00000300574|ensembl:ENST00000398970|ensembl:ENSP00000381942|refseq:NP_005197.3|refseq:NP_058431.2|ensembl:ENSG00000167193(gene)|ensembl:ENST00000300574(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001878"(response to yeast)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|dip:DIP-199N|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019900"(kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035728"(response to hepatocyte growth factor)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045121"(membrane raft)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902531"(regulation of intracellular signal transduction)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46108|rcsb pdb:1JU5|rcsb pdb:2DVJ|rcsb pdb:2EYV|rcsb pdb:2EYW|rcsb pdb:2EYX|rcsb pdb:2EYY|rcsb pdb:2EYZ|rcsb pdb:2MS4|rcsb pdb:5UL6|rcsb pdb:6ATV|reactome:R-HSA-170984|reactome:R-HSA-186763|reactome:R-HSA-2029482|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-912631|reactome:R-HSA-9664422	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/06	2015/12/09	rogid:yPJrj4jSikLFp4R3miQOPDyXrRs10090	rogid:lIXCzFxFvmvsfPaLQIKV9QS75cw9606	intact-crc:6FC58A51CE2D7696|rigid:fDh9LUeIC8vND0Wqsx7RD0IoZsU	false	35s radiolabel:?-?|sufficient binding region:697-850	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9QWY8-2	uniprotkb:P00523	intact:EBI-698524|ensembl:ENSMUSP00000135190	intact:EBI-848039|uniprotkb:Q90992|uniprotkb:Q90993|uniprotkb:Q91343|uniprotkb:Q91345|uniprotkb:Q92013|uniprotkb:Q98915|ensembl:ENSGALP00000049896|ensembl:ENSGALP00000054990|ensembl:ENSGALP00000068298	psi-mi:q9qwy8-2(display_long)|uniprotkb:SHAG1b(isoform synonym)|uniprotkb:ASAP1b(isoform synonym)|uniprotkb:Asap1(gene name)|psi-mi:Asap1(display_short)|uniprotkb:Ddef1(gene name synonym)|uniprotkb:Kiaa1249(gene name synonym)|uniprotkb:Shag1(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:src_chick(display_long)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:"MI:0096"(pull down)	Brown et al. (1998)	pubmed:9819391|imex:IM-19368	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848123|imex:IM-19368-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-698498(ddef1_mouse)|ensembl:ENSMUSG00000022377(gene)|ensembl:ENSMUST00000176384(transcript)	refseq:NP_990788.2|dip:DIP-449N|refseq:XP_015151834.1|ensembl:ENSGALG00000003855(gene)|ensembl:ENSGALT00000061823(transcript)|ensembl:ENSGALT00000070498(transcript)|ensembl:ENSGALT00000093274(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020037"(heme binding)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036035"(osteoclast development)|go:"GO:0045087"(innate immune response)|go:"GO:0045453"(bone resorption)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071253"(connexin binding)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P00523|rcsb pdb:1F1W|rcsb pdb:1F2F|rcsb pdb:1NLO|rcsb pdb:1NLP|rcsb pdb:1P13|rcsb pdb:1PRL|rcsb pdb:1PRM|rcsb pdb:1RLP|rcsb pdb:1RLQ|rcsb pdb:1SRL|rcsb pdb:1SRM|rcsb pdb:2HWO|rcsb pdb:2HWP|rcsb pdb:2OIQ|rcsb pdb:2PTK|rcsb pdb:2QI8|rcsb pdb:2QLQ|rcsb pdb:2QQ7|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3DQW|rcsb pdb:3DQX|rcsb pdb:3EL7|rcsb pdb:3EL8|rcsb pdb:3EN4|rcsb pdb:3EN5|rcsb pdb:3EN6|rcsb pdb:3EN7|rcsb pdb:3F3T|rcsb pdb:3F3U|rcsb pdb:3F3V|rcsb pdb:3F3W|rcsb pdb:3F6X|rcsb pdb:3FJ5|rcsb pdb:3G5D|rcsb pdb:3G6G|rcsb pdb:3G6H|rcsb pdb:3GEQ|rcsb pdb:3LOK|rcsb pdb:3OEZ|rcsb pdb:3OF0|rcsb pdb:3QLF|rcsb pdb:3QLG|rcsb pdb:3SVV|rcsb pdb:3TZ7|rcsb pdb:3TZ8|rcsb pdb:3TZ9|rcsb pdb:3U4W|rcsb pdb:3U51|rcsb pdb:3UQF|rcsb pdb:3UQG|rcsb pdb:4AGW|rcsb pdb:4DGG|rcsb pdb:4FIC|rcsb pdb:4HVU|rcsb pdb:4HVV|rcsb pdb:4HVW|rcsb pdb:4JZ3|rcsb pdb:4JZ4|rcsb pdb:4LE9|rcsb pdb:4LGG|rcsb pdb:4LGH|rcsb pdb:4MCV|rcsb pdb:4O2P|rcsb pdb:4OML|rcsb pdb:4OMM|rcsb pdb:4OMN|rcsb pdb:4OMO|rcsb pdb:4OMP|rcsb pdb:4OMQ|rcsb pdb:4QT7|rcsb pdb:4RTU|rcsb pdb:4RTV|rcsb pdb:4RTW|rcsb pdb:4RTX|rcsb pdb:4RTY|rcsb pdb:4RTZ|rcsb pdb:4U5J|rcsb pdb:4YBJ|rcsb pdb:4YBK|rcsb pdb:5BMM|rcsb pdb:5D10|rcsb pdb:5D11|rcsb pdb:5D12|rcsb pdb:5EC7|rcsb pdb:5ECA|rcsb pdb:5I11|rcsb pdb:5J5S|rcsb pdb:5K9I|rcsb pdb:5OAV|rcsb pdb:5OB0|rcsb pdb:5OB1|rcsb pdb:5OB2|rcsb pdb:5SWH|rcsb pdb:5SYS|rcsb pdb:5T0P|rcsb pdb:5TEH|rcsb pdb:5XP5|rcsb pdb:5XP7|rcsb pdb:6HVE|rcsb pdb:6HVF|rcsb pdb:6L8L|rcsb pdb:6WIW|rcsb pdb:6XVM|rcsb pdb:6XVN|rcsb pdb:6XVO|rcsb pdb:6XX2|rcsb pdb:6XX3|rcsb pdb:6XX4|rcsb pdb:6XX5|reactome:R-GGA-1227986|reactome:R-GGA-1251985|reactome:R-GGA-1253288|reactome:R-GGA-1257604|reactome:R-GGA-1433557|reactome:R-GGA-180292|reactome:R-GGA-186763|reactome:R-GGA-191650|reactome:R-GGA-2029481|reactome:R-GGA-210990|reactome:R-GGA-354192|reactome:R-GGA-354194|reactome:R-GGA-372708|reactome:R-GGA-389356|reactome:R-GGA-389513|reactome:R-GGA-3928662|reactome:R-GGA-3928663|reactome:R-GGA-3928664|reactome:R-GGA-3928665|reactome:R-GGA-418592|reactome:R-GGA-418594|reactome:R-GGA-418885|reactome:R-GGA-430116|reactome:R-GGA-437239|reactome:R-GGA-4420097|reactome:R-GGA-456926|reactome:R-GGA-5218921|reactome:R-GGA-5674135|reactome:R-GGA-6811558|reactome:R-GGA-8853659|reactome:R-GGA-8874081|reactome:R-GGA-8941858|reactome:R-GGA-9009391	-	-	-	comment:"Mutation analysis in two canonical SH3 binding site (P1: arg811Ala and P2: Pro910Ala-Pro913Ala) in ASAP1b show their importance for the interaction with src."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/06	2014/10/16	rogid:yPJrj4jSikLFp4R3miQOPDyXrRs10090	rogid:4zMmRUOi44prLCXBJNuTuFIMkr49031	intact-crc:EF36CB65D6E31B8E|rigid:ew9VAVunSolJ0jnPkTUV/AMR+EA	false	mutation disrupting interaction:811-811,849-849,853-853|35s radiolabel:?-?	sufficient binding region:82-145|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9QWY8-2	uniprotkb:P06241	intact:EBI-698524|ensembl:ENSMUSP00000135190	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671|ensembl:ENSP00000357656	psi-mi:q9qwy8-2(display_long)|uniprotkb:SHAG1b(isoform synonym)|uniprotkb:ASAP1b(isoform synonym)|uniprotkb:Asap1(gene name)|psi-mi:Asap1(display_short)|uniprotkb:Ddef1(gene name synonym)|uniprotkb:Kiaa1249(gene name synonym)|uniprotkb:Shag1(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:"MI:0096"(pull down)	Brown et al. (1998)	pubmed:9819391|imex:IM-19368	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848134|imex:IM-19368-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-698498(ddef1_mouse)|ensembl:ENSMUSG00000022377(gene)|ensembl:ENSMUST00000176384(transcript)	refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|dip:DIP-33876N|ensembl:ENSG00000010810(gene)|ensembl:ENST00000354650(transcript)|ensembl:ENST00000368667(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001764"(neuron migration)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0003015"(heart process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007612"(learning)|go:"GO:0007631"(feeding behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|interpro:IPR036028|interpro:IPR036860|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9670439	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/06	2014/10/16	rogid:yPJrj4jSikLFp4R3miQOPDyXrRs10090	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	intact-crc:93CF9DC18C21AE72|rigid:Jn6C20U4W+xH6Jl+KdXhYo8Vl3s	false	35s radiolabel:?-?	sufficient binding region:82..82-143..143|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9QWY8-2	uniprotkb:P07948	intact:EBI-698524|ensembl:ENSMUSP00000135190	intact:EBI-79452|ensembl:ENSP00000428924|uniprotkb:A0AVQ5|intact:EBI-6868890	psi-mi:q9qwy8-2(display_long)|uniprotkb:SHAG1b(isoform synonym)|uniprotkb:ASAP1b(isoform synonym)|uniprotkb:Asap1(gene name)|psi-mi:Asap1(display_short)|uniprotkb:Ddef1(gene name synonym)|uniprotkb:Kiaa1249(gene name synonym)|uniprotkb:Shag1(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:lyn_human(display_long)|uniprotkb:JTK8(gene name synonym)|uniprotkb:Lck/Yes-related novel protein tyrosine kinase(gene name synonym)|uniprotkb:V-yes-1 Yamaguchi sarcoma viral related oncogene homolog(gene name synonym)|uniprotkb:p53Lyn(gene name synonym)|uniprotkb:p56Lyn(gene name synonym)|uniprotkb:LYN(gene name)|psi-mi:LYN(display_short)	psi-mi:"MI:0096"(pull down)	Brown et al. (1998)	pubmed:9819391|imex:IM-19368	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848145|imex:IM-19368-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-698498(ddef1_mouse)|ensembl:ENSMUSG00000022377(gene)|ensembl:ENSMUST00000176384(transcript)	refseq:NP_001104567.1|refseq:NP_002341.1|ensembl:ENSG00000254087(gene)|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-983695|reactome:R-HSA-9664323|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002431"(Fc receptor mediated stimulatory signaling pathway)|go:"GO:0002513"(tolerance induction to self antigen)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0002576"(platelet degranulation)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0002768"(immune response-regulating cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0002902"(regulation of B cell apoptotic process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|ensembl:ENST00000519728(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006991"(response to sterol depletion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009725"(response to hormone)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016301"(kinase activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032868"(response to insulin)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043200"(response to amino acid)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050855"(regulation of B cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060369"(positive regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070304"(positive regulation of stress-activated protein kinase signaling cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070447"(positive regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070667"(negative regulation of mast cell proliferation)|go:"GO:0070668"(positive regulation of mast cell proliferation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0090025"(regulation of monocyte chemotaxis)|go:"GO:0090330"(regulation of platelet aggregation)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1902532"(negative regulation of intracellular signal transduction)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:2000670"(positive regulation of dendritic cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035748|interpro:IPR035852|interpro:IPR036028|interpro:IPR036860|mint:P07948|rcsb pdb:1W1F|rcsb pdb:1WA7|go:"GO:0099091"(postsynaptic specialization, intracellular component)|rcsb pdb:5XY1|rcsb pdb:6NMW|reactome:R-HSA-114604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2454202|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-389356|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-5621480|rcsb pdb:3A4O|reactome:R-HSA-5621575|reactome:R-HSA-5690714|reactome:R-HSA-69231|reactome:R-HSA-75892|reactome:R-HSA-9006335|reactome:R-HSA-9027276|reactome:R-HSA-9027277|reactome:R-HSA-9027283|reactome:R-HSA-9027284|reactome:R-HSA-912631|refseq:XP_016868905.1|dip:DIP-1056N	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/06	2014/10/16	rogid:yPJrj4jSikLFp4R3miQOPDyXrRs10090	rogid:SqXPSC+g2ZuGHy6TAPV4HcpXe6U9606	intact-crc:FFCDAD5AB47ACA63|rigid:DhjrVZE0j4AxV7p2BDNE2kUvChY	false	33p radiolabel:?-?	sufficient binding region:63-123|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9QWY8-1	uniprotkb:P46108	intact:EBI-698517|ensembl:ENSMUSP00000134825	intact:EBI-886|uniprotkb:B0LPE8|uniprotkb:Q96HJ0|uniprotkb:A8MWE8|uniprotkb:Q96GA9|uniprotkb:D3DTH6|intact:EBI-28974221|ensembl:ENSP00000300574|intact:EBI-16429791	psi-mi:q9qwy8-1(display_long)|uniprotkb:SHAG1a(isoform synonym)|uniprotkb:ASAP1a(isoform synonym)|uniprotkb:Kiaa1249(gene name synonym)|uniprotkb:Shag1(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:Asap1(gene name)|psi-mi:Asap1(display_short)|uniprotkb:Ddef1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:crk_human(display_long)|uniprotkb:Proto-oncogene c-Crk(gene name synonym)|uniprotkb:CRK(gene name)|psi-mi:CRK(display_short)|uniprotkb:p38(gene name synonym)	psi-mi:"MI:0096"(pull down)	Brown et al. (1998)	pubmed:9819391|imex:IM-19368	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848156|imex:IM-19368-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-698498(ddef1_mouse)|ensembl:ENSMUSG00000022377(gene)|ensembl:ENSMUST00000177374(transcript)	ensembl:ENSP00000300574|ensembl:ENST00000398970|ensembl:ENSP00000381942|refseq:NP_005197.3|refseq:NP_058431.2|ensembl:ENSG00000167193(gene)|ensembl:ENST00000300574(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001878"(response to yeast)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|dip:DIP-199N|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019900"(kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035728"(response to hepatocyte growth factor)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045121"(membrane raft)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902531"(regulation of intracellular signal transduction)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46108|rcsb pdb:1JU5|rcsb pdb:2DVJ|rcsb pdb:2EYV|rcsb pdb:2EYW|rcsb pdb:2EYX|rcsb pdb:2EYY|rcsb pdb:2EYZ|rcsb pdb:2MS4|rcsb pdb:5UL6|rcsb pdb:6ATV|reactome:R-HSA-170984|reactome:R-HSA-186763|reactome:R-HSA-2029482|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-912631|reactome:R-HSA-9664422	-	-	-	comment:"Mutation analysis in two canonical SH3 binding site (P1: arg811Ala and P2: Pro910Ala-Pro913Ala) in ASAP1b show their importance for the interaction with Crk."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/06	2015/12/09	rogid:/jhMt+/t+DTqI3ZQmzU0IMFCHdA10090	rogid:lIXCzFxFvmvsfPaLQIKV9QS75cw9606	intact-crc:99D15672F86BF2C1|rigid:QrScTIW43HQ63tKhYsYZR/q5rMo	false	mutation decreasing interaction:913-913,910-910|mutation disrupting interaction:913-913,811-811,910-910|mutation decreasing interaction:811-811|35s radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00523	uniprotkb:Q9QWY8-1	intact:EBI-848039|uniprotkb:Q90992|uniprotkb:Q90993|uniprotkb:Q91343|uniprotkb:Q91345|uniprotkb:Q92013|uniprotkb:Q98915|ensembl:ENSGALP00000049896|ensembl:ENSGALP00000054990|ensembl:ENSGALP00000068298	intact:EBI-698517|ensembl:ENSMUSP00000134825	psi-mi:src_chick(display_long)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:q9qwy8-1(display_long)|uniprotkb:SHAG1a(isoform synonym)|uniprotkb:ASAP1a(isoform synonym)|uniprotkb:Kiaa1249(gene name synonym)|uniprotkb:Shag1(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:Asap1(gene name)|psi-mi:Asap1(display_short)|uniprotkb:Ddef1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Brown et al. (1998)	pubmed:9819391|imex:IM-19368	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848170|imex:IM-19368-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_990788.2|dip:DIP-449N|refseq:XP_015151834.1|ensembl:ENSGALG00000003855(gene)|ensembl:ENSGALT00000061823(transcript)|ensembl:ENSGALT00000070498(transcript)|ensembl:ENSGALT00000093274(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020037"(heme binding)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036035"(osteoclast development)|go:"GO:0045087"(innate immune response)|go:"GO:0045453"(bone resorption)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071253"(connexin binding)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P00523|rcsb pdb:1F1W|rcsb pdb:1F2F|rcsb pdb:1NLO|rcsb pdb:1NLP|rcsb pdb:1P13|rcsb pdb:1PRL|rcsb pdb:1PRM|rcsb pdb:1RLP|rcsb pdb:1RLQ|rcsb pdb:1SRL|rcsb pdb:1SRM|rcsb pdb:2HWO|rcsb pdb:2HWP|rcsb pdb:2OIQ|rcsb pdb:2PTK|rcsb pdb:2QI8|rcsb pdb:2QLQ|rcsb pdb:2QQ7|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3DQW|rcsb pdb:3DQX|rcsb pdb:3EL7|rcsb pdb:3EL8|rcsb pdb:3EN4|rcsb pdb:3EN5|rcsb pdb:3EN6|rcsb pdb:3EN7|rcsb pdb:3F3T|rcsb pdb:3F3U|rcsb pdb:3F3V|rcsb pdb:3F3W|rcsb pdb:3F6X|rcsb pdb:3FJ5|rcsb pdb:3G5D|rcsb pdb:3G6G|rcsb pdb:3G6H|rcsb pdb:3GEQ|rcsb pdb:3LOK|rcsb pdb:3OEZ|rcsb pdb:3OF0|rcsb pdb:3QLF|rcsb pdb:3QLG|rcsb pdb:3SVV|rcsb pdb:3TZ7|rcsb pdb:3TZ8|rcsb pdb:3TZ9|rcsb pdb:3U4W|rcsb pdb:3U51|rcsb pdb:3UQF|rcsb pdb:3UQG|rcsb pdb:4AGW|rcsb pdb:4DGG|rcsb pdb:4FIC|rcsb pdb:4HVU|rcsb pdb:4HVV|rcsb pdb:4HVW|rcsb pdb:4JZ3|rcsb pdb:4JZ4|rcsb pdb:4LE9|rcsb pdb:4LGG|rcsb pdb:4LGH|rcsb pdb:4MCV|rcsb pdb:4O2P|rcsb pdb:4OML|rcsb pdb:4OMM|rcsb pdb:4OMN|rcsb pdb:4OMO|rcsb pdb:4OMP|rcsb pdb:4OMQ|rcsb pdb:4QT7|rcsb pdb:4RTU|rcsb pdb:4RTV|rcsb pdb:4RTW|rcsb pdb:4RTX|rcsb pdb:4RTY|rcsb pdb:4RTZ|rcsb pdb:4U5J|rcsb pdb:4YBJ|rcsb pdb:4YBK|rcsb pdb:5BMM|rcsb pdb:5D10|rcsb pdb:5D11|rcsb pdb:5D12|rcsb pdb:5EC7|rcsb pdb:5ECA|rcsb pdb:5I11|rcsb pdb:5J5S|rcsb pdb:5K9I|rcsb pdb:5OAV|rcsb pdb:5OB0|rcsb pdb:5OB1|rcsb pdb:5OB2|rcsb pdb:5SWH|rcsb pdb:5SYS|rcsb pdb:5T0P|rcsb pdb:5TEH|rcsb pdb:5XP5|rcsb pdb:5XP7|rcsb pdb:6HVE|rcsb pdb:6HVF|rcsb pdb:6L8L|rcsb pdb:6WIW|rcsb pdb:6XVM|rcsb pdb:6XVN|rcsb pdb:6XVO|rcsb pdb:6XX2|rcsb pdb:6XX3|rcsb pdb:6XX4|rcsb pdb:6XX5|reactome:R-GGA-1227986|reactome:R-GGA-1251985|reactome:R-GGA-1253288|reactome:R-GGA-1257604|reactome:R-GGA-1433557|reactome:R-GGA-180292|reactome:R-GGA-186763|reactome:R-GGA-191650|reactome:R-GGA-2029481|reactome:R-GGA-210990|reactome:R-GGA-354192|reactome:R-GGA-354194|reactome:R-GGA-372708|reactome:R-GGA-389356|reactome:R-GGA-389513|reactome:R-GGA-3928662|reactome:R-GGA-3928663|reactome:R-GGA-3928664|reactome:R-GGA-3928665|reactome:R-GGA-418592|reactome:R-GGA-418594|reactome:R-GGA-418885|reactome:R-GGA-430116|reactome:R-GGA-437239|reactome:R-GGA-4420097|reactome:R-GGA-456926|reactome:R-GGA-5218921|reactome:R-GGA-5674135|reactome:R-GGA-6811558|reactome:R-GGA-8853659|reactome:R-GGA-8874081|reactome:R-GGA-8941858|reactome:R-GGA-9009391	intact:EBI-698498(ddef1_mouse)|ensembl:ENSMUSG00000022377(gene)|ensembl:ENSMUST00000177374(transcript)	-	-	-	expression level:Q9QWY8-2 over-expressed|expression level:P00523 over-expressed|comment:"Mutation analysis in two canonical SH3 binding site (P1: arg811Ala and P2: Pro910Ala-Pro913Ala) in ASAP1b show their importance for the interaction with src."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/02/06	2015/12/09	rogid:4zMmRUOi44prLCXBJNuTuFIMkr49031	rogid:/jhMt+/t+DTqI3ZQmzU0IMFCHdA10090	intact-crc:532989B9DDC847D1|rigid:wjKo/5tc64eZ05Pc5AARPF39fZk	false	-	mutation decreasing interaction:811-811|mutation decreasing interaction:910-910,913-913|myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O97902	uniprotkb:P00523	intact:EBI-848008	intact:EBI-848039|uniprotkb:Q90992|uniprotkb:Q90993|uniprotkb:Q91343|uniprotkb:Q91345|uniprotkb:Q92013|uniprotkb:Q98915|ensembl:ENSGALP00000049896|ensembl:ENSGALP00000054990|ensembl:ENSGALP00000068298	psi-mi:asap1_bovin(display_long)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:src_chick(display_long)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Brown et al. (1998)	pubmed:9819391|imex:IM-19368	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848183|imex:IM-19368-14	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027267|refseq:NP_787015.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036770|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR037278|interpro:IPR043593|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)	refseq:NP_990788.2|dip:DIP-449N|refseq:XP_015151834.1|ensembl:ENSGALG00000003855(gene)|ensembl:ENSGALT00000061823(transcript)|ensembl:ENSGALT00000070498(transcript)|ensembl:ENSGALT00000093274(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020037"(heme binding)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036035"(osteoclast development)|go:"GO:0045087"(innate immune response)|go:"GO:0045453"(bone resorption)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071253"(connexin binding)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P00523|rcsb pdb:1F1W|rcsb pdb:1F2F|rcsb pdb:1NLO|rcsb pdb:1NLP|rcsb pdb:1P13|rcsb pdb:1PRL|rcsb pdb:1PRM|rcsb pdb:1RLP|rcsb pdb:1RLQ|rcsb pdb:1SRL|rcsb pdb:1SRM|rcsb pdb:2HWO|rcsb pdb:2HWP|rcsb pdb:2OIQ|rcsb pdb:2PTK|rcsb pdb:2QI8|rcsb pdb:2QLQ|rcsb pdb:2QQ7|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3DQW|rcsb pdb:3DQX|rcsb pdb:3EL7|rcsb pdb:3EL8|rcsb pdb:3EN4|rcsb pdb:3EN5|rcsb pdb:3EN6|rcsb pdb:3EN7|rcsb pdb:3F3T|rcsb pdb:3F3U|rcsb pdb:3F3V|rcsb pdb:3F3W|rcsb pdb:3F6X|rcsb pdb:3FJ5|rcsb pdb:3G5D|rcsb pdb:3G6G|rcsb pdb:3G6H|rcsb pdb:3GEQ|rcsb pdb:3LOK|rcsb pdb:3OEZ|rcsb pdb:3OF0|rcsb pdb:3QLF|rcsb pdb:3QLG|rcsb pdb:3SVV|rcsb pdb:3TZ7|rcsb pdb:3TZ8|rcsb pdb:3TZ9|rcsb pdb:3U4W|rcsb pdb:3U51|rcsb pdb:3UQF|rcsb pdb:3UQG|rcsb pdb:4AGW|rcsb pdb:4DGG|rcsb pdb:4FIC|rcsb pdb:4HVU|rcsb pdb:4HVV|rcsb pdb:4HVW|rcsb pdb:4JZ3|rcsb pdb:4JZ4|rcsb pdb:4LE9|rcsb pdb:4LGG|rcsb pdb:4LGH|rcsb pdb:4MCV|rcsb pdb:4O2P|rcsb pdb:4OML|rcsb pdb:4OMM|rcsb pdb:4OMN|rcsb pdb:4OMO|rcsb pdb:4OMP|rcsb pdb:4OMQ|rcsb pdb:4QT7|rcsb pdb:4RTU|rcsb pdb:4RTV|rcsb pdb:4RTW|rcsb pdb:4RTX|rcsb pdb:4RTY|rcsb pdb:4RTZ|rcsb pdb:4U5J|rcsb pdb:4YBJ|rcsb pdb:4YBK|rcsb pdb:5BMM|rcsb pdb:5D10|rcsb pdb:5D11|rcsb pdb:5D12|rcsb pdb:5EC7|rcsb pdb:5ECA|rcsb pdb:5I11|rcsb pdb:5J5S|rcsb pdb:5K9I|rcsb pdb:5OAV|rcsb pdb:5OB0|rcsb pdb:5OB1|rcsb pdb:5OB2|rcsb pdb:5SWH|rcsb pdb:5SYS|rcsb pdb:5T0P|rcsb pdb:5TEH|rcsb pdb:5XP5|rcsb pdb:5XP7|rcsb pdb:6HVE|rcsb pdb:6HVF|rcsb pdb:6L8L|rcsb pdb:6WIW|rcsb pdb:6XVM|rcsb pdb:6XVN|rcsb pdb:6XVO|rcsb pdb:6XX2|rcsb pdb:6XX3|rcsb pdb:6XX4|rcsb pdb:6XX5|reactome:R-GGA-1227986|reactome:R-GGA-1251985|reactome:R-GGA-1253288|reactome:R-GGA-1257604|reactome:R-GGA-1433557|reactome:R-GGA-180292|reactome:R-GGA-186763|reactome:R-GGA-191650|reactome:R-GGA-2029481|reactome:R-GGA-210990|reactome:R-GGA-354192|reactome:R-GGA-354194|reactome:R-GGA-372708|reactome:R-GGA-389356|reactome:R-GGA-389513|reactome:R-GGA-3928662|reactome:R-GGA-3928663|reactome:R-GGA-3928664|reactome:R-GGA-3928665|reactome:R-GGA-418592|reactome:R-GGA-418594|reactome:R-GGA-418885|reactome:R-GGA-430116|reactome:R-GGA-437239|reactome:R-GGA-4420097|reactome:R-GGA-456926|reactome:R-GGA-5218921|reactome:R-GGA-5674135|reactome:R-GGA-6811558|reactome:R-GGA-8853659|reactome:R-GGA-8874081|reactome:R-GGA-8941858|reactome:R-GGA-9009391	-	-	-	comment:Endogenous bovin ASAP1 was purified to homogeneity from bovin brain.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/06	2014/10/16	rogid:4mc33mmUUJpQlwmnLTradybPIdM9913	rogid:4zMmRUOi44prLCXBJNuTuFIMkr49031	intact-crc:B4D03BBBD38FAA92|rigid:nUVpvqv5b1WWptWQGaVzkKO98fA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9QWY8-2	uniprotkb:P00523	intact:EBI-698524|ensembl:ENSMUSP00000135190	intact:EBI-848039|uniprotkb:Q90992|uniprotkb:Q90993|uniprotkb:Q91343|uniprotkb:Q91345|uniprotkb:Q92013|uniprotkb:Q98915|ensembl:ENSGALP00000049896|ensembl:ENSGALP00000054990|ensembl:ENSGALP00000068298	psi-mi:q9qwy8-2(display_long)|uniprotkb:SHAG1b(isoform synonym)|uniprotkb:ASAP1b(isoform synonym)|uniprotkb:Asap1(gene name)|psi-mi:Asap1(display_short)|uniprotkb:Ddef1(gene name synonym)|uniprotkb:Kiaa1249(gene name synonym)|uniprotkb:Shag1(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:src_chick(display_long)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Brown et al. (1998)	pubmed:9819391|imex:IM-19368	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848194|imex:IM-19368-15	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-698498(ddef1_mouse)|ensembl:ENSMUSG00000022377(gene)|ensembl:ENSMUST00000176384(transcript)	refseq:NP_990788.2|dip:DIP-449N|refseq:XP_015151834.1|ensembl:ENSGALG00000003855(gene)|ensembl:ENSGALT00000061823(transcript)|ensembl:ENSGALT00000070498(transcript)|ensembl:ENSGALT00000093274(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020037"(heme binding)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036035"(osteoclast development)|go:"GO:0045087"(innate immune response)|go:"GO:0045453"(bone resorption)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071253"(connexin binding)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P00523|rcsb pdb:1F1W|rcsb pdb:1F2F|rcsb pdb:1NLO|rcsb pdb:1NLP|rcsb pdb:1P13|rcsb pdb:1PRL|rcsb pdb:1PRM|rcsb pdb:1RLP|rcsb pdb:1RLQ|rcsb pdb:1SRL|rcsb pdb:1SRM|rcsb pdb:2HWO|rcsb pdb:2HWP|rcsb pdb:2OIQ|rcsb pdb:2PTK|rcsb pdb:2QI8|rcsb pdb:2QLQ|rcsb pdb:2QQ7|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3DQW|rcsb pdb:3DQX|rcsb pdb:3EL7|rcsb pdb:3EL8|rcsb pdb:3EN4|rcsb pdb:3EN5|rcsb pdb:3EN6|rcsb pdb:3EN7|rcsb pdb:3F3T|rcsb pdb:3F3U|rcsb pdb:3F3V|rcsb pdb:3F3W|rcsb pdb:3F6X|rcsb pdb:3FJ5|rcsb pdb:3G5D|rcsb pdb:3G6G|rcsb pdb:3G6H|rcsb pdb:3GEQ|rcsb pdb:3LOK|rcsb pdb:3OEZ|rcsb pdb:3OF0|rcsb pdb:3QLF|rcsb pdb:3QLG|rcsb pdb:3SVV|rcsb pdb:3TZ7|rcsb pdb:3TZ8|rcsb pdb:3TZ9|rcsb pdb:3U4W|rcsb pdb:3U51|rcsb pdb:3UQF|rcsb pdb:3UQG|rcsb pdb:4AGW|rcsb pdb:4DGG|rcsb pdb:4FIC|rcsb pdb:4HVU|rcsb pdb:4HVV|rcsb pdb:4HVW|rcsb pdb:4JZ3|rcsb pdb:4JZ4|rcsb pdb:4LE9|rcsb pdb:4LGG|rcsb pdb:4LGH|rcsb pdb:4MCV|rcsb pdb:4O2P|rcsb pdb:4OML|rcsb pdb:4OMM|rcsb pdb:4OMN|rcsb pdb:4OMO|rcsb pdb:4OMP|rcsb pdb:4OMQ|rcsb pdb:4QT7|rcsb pdb:4RTU|rcsb pdb:4RTV|rcsb pdb:4RTW|rcsb pdb:4RTX|rcsb pdb:4RTY|rcsb pdb:4RTZ|rcsb pdb:4U5J|rcsb pdb:4YBJ|rcsb pdb:4YBK|rcsb pdb:5BMM|rcsb pdb:5D10|rcsb pdb:5D11|rcsb pdb:5D12|rcsb pdb:5EC7|rcsb pdb:5ECA|rcsb pdb:5I11|rcsb pdb:5J5S|rcsb pdb:5K9I|rcsb pdb:5OAV|rcsb pdb:5OB0|rcsb pdb:5OB1|rcsb pdb:5OB2|rcsb pdb:5SWH|rcsb pdb:5SYS|rcsb pdb:5T0P|rcsb pdb:5TEH|rcsb pdb:5XP5|rcsb pdb:5XP7|rcsb pdb:6HVE|rcsb pdb:6HVF|rcsb pdb:6L8L|rcsb pdb:6WIW|rcsb pdb:6XVM|rcsb pdb:6XVN|rcsb pdb:6XVO|rcsb pdb:6XX2|rcsb pdb:6XX3|rcsb pdb:6XX4|rcsb pdb:6XX5|reactome:R-GGA-1227986|reactome:R-GGA-1251985|reactome:R-GGA-1253288|reactome:R-GGA-1257604|reactome:R-GGA-1433557|reactome:R-GGA-180292|reactome:R-GGA-186763|reactome:R-GGA-191650|reactome:R-GGA-2029481|reactome:R-GGA-210990|reactome:R-GGA-354192|reactome:R-GGA-354194|reactome:R-GGA-372708|reactome:R-GGA-389356|reactome:R-GGA-389513|reactome:R-GGA-3928662|reactome:R-GGA-3928663|reactome:R-GGA-3928664|reactome:R-GGA-3928665|reactome:R-GGA-418592|reactome:R-GGA-418594|reactome:R-GGA-418885|reactome:R-GGA-430116|reactome:R-GGA-437239|reactome:R-GGA-4420097|reactome:R-GGA-456926|reactome:R-GGA-5218921|reactome:R-GGA-5674135|reactome:R-GGA-6811558|reactome:R-GGA-8853659|reactome:R-GGA-8874081|reactome:R-GGA-8941858|reactome:R-GGA-9009391	-	-	-	expression level:P00523 over-expressed|expression level:Q9QWY8-2 over-expressed|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/02/06	2014/10/16	rogid:yPJrj4jSikLFp4R3miQOPDyXrRs10090	rogid:4zMmRUOi44prLCXBJNuTuFIMkr49031	intact-crc:FFB952FE1AA2FAB7|rigid:ew9VAVunSolJ0jnPkTUV/AMR+EA	false	myc tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)