#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P61972 uniprotkb:P62825 intact:EBI-1026845|uniprotkb:P13662|ensembl:ENSRNOP00000025608 intact:EBI-286616|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9CZA2|uniprotkb:Q9UEU9|uniprotkb:Q9UDJ5 psi-mi:ntf2_rat(display_long)|uniprotkb:Nutf2(gene name)|psi-mi:Nutf2(display_short)|uniprotkb:Ntf2(gene name synonym) psi-mi:ran_canlf(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short) psi-mi:"MI:0114"(x-ray crystallography) Stewart et al. (1998) pubmed:9533885 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1026859|rcsb pdb:1A2K - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1359213|refseq:NP_001007630.1|ensembl:ENSRNOG00000018945(gene)|ensembl:ENSRNOT00000025608(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:1904046"(negative regulation of vascular endothelial growth factor production)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|rcsb pdb:1A2K|rcsb pdb:1AR0|rcsb pdb:1ASK|rcsb pdb:1GY6|rcsb pdb:1JB2|rcsb pdb:1JB4|rcsb pdb:1JB5|rcsb pdb:1OUN|rcsb pdb:1U5O|rcsb pdb:5BXQ|rcsb pdb:1QMA|refseq:XP_006255542.1 rcsb pdb:5YU6|refseq:NP_001181913.1|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|rcsb pdb:1A2K|rcsb pdb:1BYU|rcsb pdb:1QG2|rcsb pdb:1QG4|rcsb pdb:1WA5|rcsb pdb:2BKU|rcsb pdb:3A6P|rcsb pdb:3RAN|rcsb pdb:5BXQ|interpro:IPR027417|rcsb pdb:3W3Z|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016442"(RISC complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:1905172"(RISC complex binding) - - - assembly:tetrameric, multimeric|3d-r-factors:working 78.500%, free 72.700%|3d-resolution:2.5A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:hDy30rHCK1a4LjUfAWtf1DEu8n810116 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9615 intact-crc:FAFC85D1E5227A5D|rigid:NyMDvRtoe0bqpNL6y85U3s2pTiM false sufficient binding region:1-127 sufficient binding region:?-? 2 3 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)