#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q12018	uniprotkb:P52286	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903114|imex:IM-19845-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:22BC8B35034EDDEF	crc64:746DDE6470A69432	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	intact-crc:868127BD14674F54|rigid:jOTJGUJ8/FiR/WQblFXHrdihz0k	false	necessary binding region:1-280	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07834	uniprotkb:Q12018	intact:EBI-4434|ensemblfungi:YFL009W|uniprotkb:D6VTM1	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	psi-mi:cdc4_yeast(display_long)|uniprotkb:CDC4(gene name)|psi-mi:CDC4(display_short)|uniprotkb:YFL009W(locus name)|uniprotkb:F-box protein CDC4(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC4(gene name synonym)	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-904939|imex:IM-19845-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SCE-174113|reactome:R-SCE-8951664|reactome:R-SCE-983168|ensemblfungi:YFL009W(gene)|ensemblfungi:YFL009W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030686"(90S preribosome)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0043130"(ubiquitin binding)|refseq:NP_116585.1|sgd:S000001885|dip:DIP-1625N|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR031740|interpro:IPR036047|interpro:IPR036322|rcsb pdb:1NEX|rcsb pdb:2P63|rcsb pdb:3MKS|rcsb pdb:3V7D	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:0348F2F8FA78F3BC	crc64:22BC8B35034EDDEF	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:KUKB7HDw6k4t7Gb1pDGW8P5J1kw559292	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	intact-crc:9CC98193B98B3BA4|rigid:mhSL15yv5GpVIVfZtczC9VyMGGA	false	-	necessary binding region:1-280	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39014	uniprotkb:Q12018	intact:EBI-11507|uniprotkb:D6VVN6|ensemblfungi:YIL046W	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	psi-mi:met30_yeast(display_long)|uniprotkb:YIL046W(locus name)|uniprotkb:MET30(gene name)|psi-mi:MET30(display_short)|uniprotkb:Methionine-requiring protein 30(gene name synonym)|uniprotkb:"E3 ubiquitin ligase complex SCF(Met30) subunit MET30"(gene name synonym)	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-904946|imex:IM-19845-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YIL046W_mRNA(transcript)|ensemblfungi:YIL046W(gene)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046686"(response to cadmium ion)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|refseq:NP_012218.1|sgd:S000001308|mint:P39014|dip:DIP-1439N	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:5135D4BCA2E1EB97	crc64:22BC8B35034EDDEF	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:B138OcWsG8zW/eFMselD2pFyy5c559292	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	intact-crc:E91802E3F6EAE75F|rigid:aZi2RtDJzeshkpPSq3HPCr7EOKo	false	-	necessary binding region:1-280	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12018	uniprotkb:P14682	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	intact:EBI-19730|uniprotkb:D6VS40|ensemblfungi:YDR054C	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:ubc3_yeast(display_long)|uniprotkb:CDC34(gene name)|psi-mi:CDC34(display_short)|uniprotkb:UBC3(gene name synonym)|uniprotkb:DNA6(gene name synonym)|uniprotkb:YDR054C(locus name)|uniprotkb:YD9609.08C(orf name)|uniprotkb:D4211(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Cell division control protein 34(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC34(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903157|imex:IM-19845-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	refseq:NP_010339.1|sgd:S000002461|ensemblfungi:YDR054C(gene)|ensemblfungi:YDR054C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:6NYA|rcsb pdb:6NYD|rcsb pdb:7K5J|reactome:R-SCE-8866652|reactome:R-SCE-983168|dip:DIP-1618N|mint:P14682	-	crc64:22BC8B35034EDDEF	crc64:1CE3E0C3AB1436DC	comment:Reveals a specific interaction between Cdc53 and Cbf3d, Cdc4 and Cdc34|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	rogid:1GaQJnMKE90j9Egn6PJsANrxSzg559292	intact-crc:D40DF79146659208|rigid:m92m4H/tNvBdJoJ/gE5769haFYo	false	myc tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12018	uniprotkb:P07834	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	intact:EBI-4434|ensemblfungi:YFL009W|uniprotkb:D6VTM1	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:cdc4_yeast(display_long)|uniprotkb:CDC4(gene name)|psi-mi:CDC4(display_short)|uniprotkb:YFL009W(locus name)|uniprotkb:F-box protein CDC4(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903157|imex:IM-19845-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	reactome:R-SCE-174113|reactome:R-SCE-8951664|reactome:R-SCE-983168|ensemblfungi:YFL009W(gene)|ensemblfungi:YFL009W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030686"(90S preribosome)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0043130"(ubiquitin binding)|refseq:NP_116585.1|sgd:S000001885|dip:DIP-1625N|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR031740|interpro:IPR036047|interpro:IPR036322|rcsb pdb:1NEX|rcsb pdb:2P63|rcsb pdb:3MKS|rcsb pdb:3V7D	-	crc64:22BC8B35034EDDEF	crc64:0348F2F8FA78F3BC	comment:Reveals a specific interaction between Cdc53 and Cbf3d, Cdc4 and Cdc34|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	rogid:KUKB7HDw6k4t7Gb1pDGW8P5J1kw559292	intact-crc:D40DF79146659208|rigid:m92m4H/tNvBdJoJ/gE5769haFYo	false	myc tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12018	uniprotkb:P52286	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903157|imex:IM-19845-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:22BC8B35034EDDEF	crc64:746DDE6470A69432	comment:Reveals a specific interaction between Cdc53 and Cbf3d, Cdc4 and Cdc34|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	intact-crc:D40DF79146659208|rigid:m92m4H/tNvBdJoJ/gE5769haFYo	false	myc tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P52286	uniprotkb:P14682	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	intact:EBI-19730|uniprotkb:D6VS40|ensemblfungi:YDR054C	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:ubc3_yeast(display_long)|uniprotkb:CDC34(gene name)|psi-mi:CDC34(display_short)|uniprotkb:UBC3(gene name synonym)|uniprotkb:DNA6(gene name synonym)|uniprotkb:YDR054C(locus name)|uniprotkb:YD9609.08C(orf name)|uniprotkb:D4211(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Cell division control protein 34(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC34(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903172|imex:IM-19845-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	refseq:NP_010339.1|sgd:S000002461|ensemblfungi:YDR054C(gene)|ensemblfungi:YDR054C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:6NYA|rcsb pdb:6NYD|rcsb pdb:7K5J|reactome:R-SCE-8866652|reactome:R-SCE-983168|dip:DIP-1618N|mint:P14682	-	crc64:746DDE6470A69432	crc64:1CE3E0C3AB1436DC	comment:Reveals a specific interaction between Cbf3d and Cdc53, Cdc4 and Cdc34 indicating that Cdc53 forms a multiprotein complex in-vivo with these proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	rogid:1GaQJnMKE90j9Egn6PJsANrxSzg559292	intact-crc:D31BF58BD6E19DE6|rigid:m92m4H/tNvBdJoJ/gE5769haFYo	false	ha tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P52286	uniprotkb:P07834	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	intact:EBI-4434|ensemblfungi:YFL009W|uniprotkb:D6VTM1	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:cdc4_yeast(display_long)|uniprotkb:CDC4(gene name)|psi-mi:CDC4(display_short)|uniprotkb:YFL009W(locus name)|uniprotkb:F-box protein CDC4(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903172|imex:IM-19845-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	reactome:R-SCE-174113|reactome:R-SCE-8951664|reactome:R-SCE-983168|ensemblfungi:YFL009W(gene)|ensemblfungi:YFL009W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030686"(90S preribosome)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0043130"(ubiquitin binding)|refseq:NP_116585.1|sgd:S000001885|dip:DIP-1625N|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR031740|interpro:IPR036047|interpro:IPR036322|rcsb pdb:1NEX|rcsb pdb:2P63|rcsb pdb:3MKS|rcsb pdb:3V7D	-	crc64:746DDE6470A69432	crc64:0348F2F8FA78F3BC	comment:Reveals a specific interaction between Cbf3d and Cdc53, Cdc4 and Cdc34 indicating that Cdc53 forms a multiprotein complex in-vivo with these proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	rogid:KUKB7HDw6k4t7Gb1pDGW8P5J1kw559292	intact-crc:D31BF58BD6E19DE6|rigid:m92m4H/tNvBdJoJ/gE5769haFYo	false	ha tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P52286	uniprotkb:Q12018	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903172|imex:IM-19845-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:746DDE6470A69432	crc64:22BC8B35034EDDEF	comment:Reveals a specific interaction between Cbf3d and Cdc53, Cdc4 and Cdc34 indicating that Cdc53 forms a multiprotein complex in-vivo with these proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	intact-crc:D31BF58BD6E19DE6|rigid:m92m4H/tNvBdJoJ/gE5769haFYo	false	ha tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P39014	uniprotkb:P52286	intact:EBI-11507|uniprotkb:D6VVN6|ensemblfungi:YIL046W	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	psi-mi:met30_yeast(display_long)|uniprotkb:YIL046W(locus name)|uniprotkb:MET30(gene name)|psi-mi:MET30(display_short)|uniprotkb:Methionine-requiring protein 30(gene name synonym)|uniprotkb:"E3 ubiquitin ligase complex SCF(Met30) subunit MET30"(gene name synonym)	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903234|imex:IM-19845-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YIL046W_mRNA(transcript)|ensemblfungi:YIL046W(gene)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046686"(response to cadmium ion)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|refseq:NP_012218.1|sgd:S000001308|mint:P39014|dip:DIP-1439N	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:5135D4BCA2E1EB97	crc64:746DDE6470A69432	comment:Revealed the presence of both Cdc53 and Cbf3d in Met30 immune complexes.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:B138OcWsG8zW/eFMselD2pFyy5c559292	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	intact-crc:2B7A9F7C7EE9C806|rigid:IBvsTubCsprziKimfwvXnGtMhto	false	ha tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P39014	uniprotkb:Q12018	intact:EBI-11507|uniprotkb:D6VVN6|ensemblfungi:YIL046W	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	psi-mi:met30_yeast(display_long)|uniprotkb:YIL046W(locus name)|uniprotkb:MET30(gene name)|psi-mi:MET30(display_short)|uniprotkb:Methionine-requiring protein 30(gene name synonym)|uniprotkb:"E3 ubiquitin ligase complex SCF(Met30) subunit MET30"(gene name synonym)	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903234|imex:IM-19845-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YIL046W_mRNA(transcript)|ensemblfungi:YIL046W(gene)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046686"(response to cadmium ion)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|refseq:NP_012218.1|sgd:S000001308|mint:P39014|dip:DIP-1439N	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:5135D4BCA2E1EB97	crc64:22BC8B35034EDDEF	comment:Revealed the presence of both Cdc53 and Cbf3d in Met30 immune complexes.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:B138OcWsG8zW/eFMselD2pFyy5c559292	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	intact-crc:2B7A9F7C7EE9C806|rigid:IBvsTubCsprziKimfwvXnGtMhto	false	ha tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P24814	uniprotkb:Q12018	intact:EBI-7898|uniprotkb:D6VWQ8|ensemblfungi:YJR090C	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	psi-mi:grr1_yeast(display_long)|uniprotkb:GRR1(gene name)|psi-mi:GRR1(display_short)|uniprotkb:CAT80(gene name synonym)|uniprotkb:COT2(gene name synonym)|uniprotkb:YJR090C(locus name)|uniprotkb:J1885(orf name)|uniprotkb:F-box and leucine-rich repeat protein GRR1(gene name synonym)|uniprotkb:F-box/LRR-repeat protein GRR1(gene name synonym)	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903250|imex:IM-19845-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012623.1|sgd:S000003850|mint:P24814|dip:DIP-1626N|ensemblfungi:YJR090C(gene)|ensemblfungi:YJR090C_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0071406"(cellular response to methylmercury)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|reactome:R-SCE-163210|reactome:R-SCE-8949613	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:6BB6C46611E6F825	crc64:22BC8B35034EDDEF	comment:Reveals that Cdc53 specifically coimmunopreciptated with HA-tagged Grr1 as did Cbf3d.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:0s/WFupjCQeASvFVM+A9mSskzXY559292	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	intact-crc:437E16CCDEDEE53C|rigid:v9ycgcROkPN7srp2gZuhiqOoLAY	false	ha tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P24814	uniprotkb:P52286	intact:EBI-7898|uniprotkb:D6VWQ8|ensemblfungi:YJR090C	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	psi-mi:grr1_yeast(display_long)|uniprotkb:GRR1(gene name)|psi-mi:GRR1(display_short)|uniprotkb:CAT80(gene name synonym)|uniprotkb:COT2(gene name synonym)|uniprotkb:YJR090C(locus name)|uniprotkb:J1885(orf name)|uniprotkb:F-box and leucine-rich repeat protein GRR1(gene name synonym)|uniprotkb:F-box/LRR-repeat protein GRR1(gene name synonym)	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903250|imex:IM-19845-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012623.1|sgd:S000003850|mint:P24814|dip:DIP-1626N|ensemblfungi:YJR090C(gene)|ensemblfungi:YJR090C_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0071406"(cellular response to methylmercury)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|reactome:R-SCE-163210|reactome:R-SCE-8949613	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:6BB6C46611E6F825	crc64:746DDE6470A69432	comment:Reveals that Cdc53 specifically coimmunopreciptated with HA-tagged Grr1 as did Cbf3d.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:0s/WFupjCQeASvFVM+A9mSskzXY559292	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	intact-crc:437E16CCDEDEE53C|rigid:v9ycgcROkPN7srp2gZuhiqOoLAY	false	ha tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P07834	uniprotkb:P52286	intact:EBI-4434|ensemblfungi:YFL009W|uniprotkb:D6VTM1	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	psi-mi:cdc4_yeast(display_long)|uniprotkb:CDC4(gene name)|psi-mi:CDC4(display_short)|uniprotkb:YFL009W(locus name)|uniprotkb:F-box protein CDC4(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC4(gene name synonym)	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903262|imex:IM-19845-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SCE-174113|reactome:R-SCE-8951664|reactome:R-SCE-983168|ensemblfungi:YFL009W(gene)|ensemblfungi:YFL009W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030686"(90S preribosome)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0043130"(ubiquitin binding)|refseq:NP_116585.1|sgd:S000001885|dip:DIP-1625N|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR031740|interpro:IPR036047|interpro:IPR036322|rcsb pdb:1NEX|rcsb pdb:2P63|rcsb pdb:3MKS|rcsb pdb:3V7D	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:0348F2F8FA78F3BC	crc64:746DDE6470A69432	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:KUKB7HDw6k4t7Gb1pDGW8P5J1kw559292	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	intact-crc:CB15DC7AD8166B50|rigid:ypFGKiAifayW+iSTePhjoPvQnOU	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P07834	uniprotkb:Q12018	intact:EBI-4434|ensemblfungi:YFL009W|uniprotkb:D6VTM1	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	psi-mi:cdc4_yeast(display_long)|uniprotkb:CDC4(gene name)|psi-mi:CDC4(display_short)|uniprotkb:YFL009W(locus name)|uniprotkb:F-box protein CDC4(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC4(gene name synonym)	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903262|imex:IM-19845-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SCE-174113|reactome:R-SCE-8951664|reactome:R-SCE-983168|ensemblfungi:YFL009W(gene)|ensemblfungi:YFL009W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030686"(90S preribosome)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0043130"(ubiquitin binding)|refseq:NP_116585.1|sgd:S000001885|dip:DIP-1625N|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR031740|interpro:IPR036047|interpro:IPR036322|rcsb pdb:1NEX|rcsb pdb:2P63|rcsb pdb:3MKS|rcsb pdb:3V7D	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:0348F2F8FA78F3BC	crc64:22BC8B35034EDDEF	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:KUKB7HDw6k4t7Gb1pDGW8P5J1kw559292	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	intact-crc:CB15DC7AD8166B50|rigid:ypFGKiAifayW+iSTePhjoPvQnOU	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12018	uniprotkb:P39014	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	intact:EBI-11507|uniprotkb:D6VVN6|ensemblfungi:YIL046W	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:met30_yeast(display_long)|uniprotkb:YIL046W(locus name)|uniprotkb:MET30(gene name)|psi-mi:MET30(display_short)|uniprotkb:Methionine-requiring protein 30(gene name synonym)|uniprotkb:"E3 ubiquitin ligase complex SCF(Met30) subunit MET30"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903309|imex:IM-19845-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	ensemblfungi:YIL046W_mRNA(transcript)|ensemblfungi:YIL046W(gene)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046686"(response to cadmium ion)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|refseq:NP_012218.1|sgd:S000001308|mint:P39014|dip:DIP-1439N	-	crc64:22BC8B35034EDDEF	crc64:5135D4BCA2E1EB97	comment:Reveals that wild type Cdc53 interacts with Ubc3, Cbf3d and with the 3 F-box proteins Cdc4, Met30 and Grr1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	rogid:B138OcWsG8zW/eFMselD2pFyy5c559292	intact-crc:EEBE616E1539605A|rigid:yymxWSG3difsjR3EeVcr+g7MatU	false	myc tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12018	uniprotkb:P24814	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	intact:EBI-7898|uniprotkb:D6VWQ8|ensemblfungi:YJR090C	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:grr1_yeast(display_long)|uniprotkb:GRR1(gene name)|psi-mi:GRR1(display_short)|uniprotkb:CAT80(gene name synonym)|uniprotkb:COT2(gene name synonym)|uniprotkb:YJR090C(locus name)|uniprotkb:J1885(orf name)|uniprotkb:F-box and leucine-rich repeat protein GRR1(gene name synonym)|uniprotkb:F-box/LRR-repeat protein GRR1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903309|imex:IM-19845-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	refseq:NP_012623.1|sgd:S000003850|mint:P24814|dip:DIP-1626N|ensemblfungi:YJR090C(gene)|ensemblfungi:YJR090C_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0071406"(cellular response to methylmercury)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|reactome:R-SCE-163210|reactome:R-SCE-8949613	-	crc64:22BC8B35034EDDEF	crc64:6BB6C46611E6F825	comment:Reveals that wild type Cdc53 interacts with Ubc3, Cbf3d and with the 3 F-box proteins Cdc4, Met30 and Grr1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	rogid:0s/WFupjCQeASvFVM+A9mSskzXY559292	intact-crc:EEBE616E1539605A|rigid:yymxWSG3difsjR3EeVcr+g7MatU	false	myc tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12018	uniprotkb:P14682	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	intact:EBI-19730|uniprotkb:D6VS40|ensemblfungi:YDR054C	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:ubc3_yeast(display_long)|uniprotkb:CDC34(gene name)|psi-mi:CDC34(display_short)|uniprotkb:UBC3(gene name synonym)|uniprotkb:DNA6(gene name synonym)|uniprotkb:YDR054C(locus name)|uniprotkb:YD9609.08C(orf name)|uniprotkb:D4211(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Cell division control protein 34(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC34(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903309|imex:IM-19845-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	refseq:NP_010339.1|sgd:S000002461|ensemblfungi:YDR054C(gene)|ensemblfungi:YDR054C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:6NYA|rcsb pdb:6NYD|rcsb pdb:7K5J|reactome:R-SCE-8866652|reactome:R-SCE-983168|dip:DIP-1618N|mint:P14682	-	crc64:22BC8B35034EDDEF	crc64:1CE3E0C3AB1436DC	comment:Reveals that wild type Cdc53 interacts with Ubc3, Cbf3d and with the 3 F-box proteins Cdc4, Met30 and Grr1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	rogid:1GaQJnMKE90j9Egn6PJsANrxSzg559292	intact-crc:EEBE616E1539605A|rigid:yymxWSG3difsjR3EeVcr+g7MatU	false	myc tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12018	uniprotkb:P07834	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	intact:EBI-4434|ensemblfungi:YFL009W|uniprotkb:D6VTM1	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:cdc4_yeast(display_long)|uniprotkb:CDC4(gene name)|psi-mi:CDC4(display_short)|uniprotkb:YFL009W(locus name)|uniprotkb:F-box protein CDC4(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903309|imex:IM-19845-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	reactome:R-SCE-174113|reactome:R-SCE-8951664|reactome:R-SCE-983168|ensemblfungi:YFL009W(gene)|ensemblfungi:YFL009W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030686"(90S preribosome)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0043130"(ubiquitin binding)|refseq:NP_116585.1|sgd:S000001885|dip:DIP-1625N|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR031740|interpro:IPR036047|interpro:IPR036322|rcsb pdb:1NEX|rcsb pdb:2P63|rcsb pdb:3MKS|rcsb pdb:3V7D	-	crc64:22BC8B35034EDDEF	crc64:0348F2F8FA78F3BC	comment:Reveals that wild type Cdc53 interacts with Ubc3, Cbf3d and with the 3 F-box proteins Cdc4, Met30 and Grr1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	rogid:KUKB7HDw6k4t7Gb1pDGW8P5J1kw559292	intact-crc:EEBE616E1539605A|rigid:yymxWSG3difsjR3EeVcr+g7MatU	false	myc tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12018	uniprotkb:P52286	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-903309|imex:IM-19845-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:22BC8B35034EDDEF	crc64:746DDE6470A69432	comment:Reveals that wild type Cdc53 interacts with Ubc3, Cbf3d and with the 3 F-box proteins Cdc4, Met30 and Grr1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	intact-crc:EEBE616E1539605A|rigid:yymxWSG3difsjR3EeVcr+g7MatU	false	myc tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12018	uniprotkb:P39014	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	intact:EBI-11507|uniprotkb:D6VVN6|ensemblfungi:YIL046W	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:met30_yeast(display_long)|uniprotkb:YIL046W(locus name)|uniprotkb:MET30(gene name)|psi-mi:MET30(display_short)|uniprotkb:Methionine-requiring protein 30(gene name synonym)|uniprotkb:"E3 ubiquitin ligase complex SCF(Met30) subunit MET30"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-905324|imex:IM-19845-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	ensemblfungi:YIL046W_mRNA(transcript)|ensemblfungi:YIL046W(gene)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046686"(response to cadmium ion)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|refseq:NP_012218.1|sgd:S000001308|mint:P39014|dip:DIP-1439N	-	crc64:22BC8B35034EDDEF	crc64:5135D4BCA2E1EB97	comment:"Reveals that deletion of the Cdc53 amino terminal residues (AA 9-280) completely disrupts Cbf3d binding and binding to the 3 F-box proteins Cdc4, Met30 and Grr1."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	rogid:B138OcWsG8zW/eFMselD2pFyy5c559292	intact-crc:A50A4EAFEF5D6F1D|rigid:2zayxItVgaXvLdeESJvTfIwFliY	false	myc tag:?-?|necessary binding region:9-280	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12018	uniprotkb:P24814	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	intact:EBI-7898|uniprotkb:D6VWQ8|ensemblfungi:YJR090C	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:grr1_yeast(display_long)|uniprotkb:GRR1(gene name)|psi-mi:GRR1(display_short)|uniprotkb:CAT80(gene name synonym)|uniprotkb:COT2(gene name synonym)|uniprotkb:YJR090C(locus name)|uniprotkb:J1885(orf name)|uniprotkb:F-box and leucine-rich repeat protein GRR1(gene name synonym)|uniprotkb:F-box/LRR-repeat protein GRR1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-905324|imex:IM-19845-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	refseq:NP_012623.1|sgd:S000003850|mint:P24814|dip:DIP-1626N|ensemblfungi:YJR090C(gene)|ensemblfungi:YJR090C_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0071406"(cellular response to methylmercury)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|reactome:R-SCE-163210|reactome:R-SCE-8949613	-	crc64:22BC8B35034EDDEF	crc64:6BB6C46611E6F825	comment:"Reveals that deletion of the Cdc53 amino terminal residues (AA 9-280) completely disrupts Cbf3d binding and binding to the 3 F-box proteins Cdc4, Met30 and Grr1."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	rogid:0s/WFupjCQeASvFVM+A9mSskzXY559292	intact-crc:A50A4EAFEF5D6F1D|rigid:2zayxItVgaXvLdeESJvTfIwFliY	false	myc tag:?-?|necessary binding region:9-280	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12018	uniprotkb:P52286	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-905324|imex:IM-19845-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:22BC8B35034EDDEF	crc64:746DDE6470A69432	comment:"Reveals that deletion of the Cdc53 amino terminal residues (AA 9-280) completely disrupts Cbf3d binding and binding to the 3 F-box proteins Cdc4, Met30 and Grr1."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	intact-crc:A50A4EAFEF5D6F1D|rigid:2zayxItVgaXvLdeESJvTfIwFliY	false	myc tag:?-?|necessary binding region:9-280	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12018	uniprotkb:P07834	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	intact:EBI-4434|ensemblfungi:YFL009W|uniprotkb:D6VTM1	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:cdc4_yeast(display_long)|uniprotkb:CDC4(gene name)|psi-mi:CDC4(display_short)|uniprotkb:YFL009W(locus name)|uniprotkb:F-box protein CDC4(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-905324|imex:IM-19845-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	reactome:R-SCE-174113|reactome:R-SCE-8951664|reactome:R-SCE-983168|ensemblfungi:YFL009W(gene)|ensemblfungi:YFL009W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030686"(90S preribosome)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0043130"(ubiquitin binding)|refseq:NP_116585.1|sgd:S000001885|dip:DIP-1625N|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR031740|interpro:IPR036047|interpro:IPR036322|rcsb pdb:1NEX|rcsb pdb:2P63|rcsb pdb:3MKS|rcsb pdb:3V7D	-	crc64:22BC8B35034EDDEF	crc64:0348F2F8FA78F3BC	comment:"Reveals that deletion of the Cdc53 amino terminal residues (AA 9-280) completely disrupts Cbf3d binding and binding to the 3 F-box proteins Cdc4, Met30 and Grr1."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	rogid:KUKB7HDw6k4t7Gb1pDGW8P5J1kw559292	intact-crc:A50A4EAFEF5D6F1D|rigid:2zayxItVgaXvLdeESJvTfIwFliY	false	myc tag:?-?|necessary binding region:9-280	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P14682	uniprotkb:Q12018	intact:EBI-19730|uniprotkb:D6VS40|ensemblfungi:YDR054C	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	psi-mi:ubc3_yeast(display_long)|uniprotkb:CDC34(gene name)|psi-mi:CDC34(display_short)|uniprotkb:UBC3(gene name synonym)|uniprotkb:DNA6(gene name synonym)|uniprotkb:YDR054C(locus name)|uniprotkb:YD9609.08C(orf name)|uniprotkb:D4211(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Cell division control protein 34(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC34(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 3(gene name synonym)	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-905339|imex:IM-19845-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010339.1|sgd:S000002461|ensemblfungi:YDR054C(gene)|ensemblfungi:YDR054C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:6NYA|rcsb pdb:6NYD|rcsb pdb:7K5J|reactome:R-SCE-8866652|reactome:R-SCE-983168|dip:DIP-1618N|mint:P14682	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:1CE3E0C3AB1436DC	crc64:22BC8B35034EDDEF	comment:"Deletion of an internal region of Cdc53 (AA 448-748) abrogated Ubc3 binding but did not affect binding to Cbf3d or any of the F-box proteins.  Additionally mutation of arg448cys (as found in the cdc53-1 mutant strain) disrupted binding to Ubc3."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:1GaQJnMKE90j9Egn6PJsANrxSzg559292	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	intact-crc:F48A0F49E9703214|rigid:ebTVIkRIOcc6ZcZmvV9/DG4bCuk	false	-	myc tag:?-?|necessary binding region:448-748|mutation disrupting interaction:488-488	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12018	uniprotkb:P07834	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	intact:EBI-4434|ensemblfungi:YFL009W|uniprotkb:D6VTM1	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:cdc4_yeast(display_long)|uniprotkb:CDC4(gene name)|psi-mi:CDC4(display_short)|uniprotkb:YFL009W(locus name)|uniprotkb:F-box protein CDC4(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-904955|imex:IM-19845-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	reactome:R-SCE-174113|reactome:R-SCE-8951664|reactome:R-SCE-983168|ensemblfungi:YFL009W(gene)|ensemblfungi:YFL009W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030686"(90S preribosome)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0043130"(ubiquitin binding)|refseq:NP_116585.1|sgd:S000001885|dip:DIP-1625N|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR031740|interpro:IPR036047|interpro:IPR036322|rcsb pdb:1NEX|rcsb pdb:2P63|rcsb pdb:3MKS|rcsb pdb:3V7D	-	crc64:22BC8B35034EDDEF	crc64:0348F2F8FA78F3BC	comment:Shows that the F-box protein Cdc4 does not interact with other F-box proteins but does interact with Cdc53.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	rogid:KUKB7HDw6k4t7Gb1pDGW8P5J1kw559292	intact-crc:12C954CCC37C8693|rigid:mhSL15yv5GpVIVfZtczC9VyMGGA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P24814	uniprotkb:Q12018	intact:EBI-7898|uniprotkb:D6VWQ8|ensemblfungi:YJR090C	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	psi-mi:grr1_yeast(display_long)|uniprotkb:GRR1(gene name)|psi-mi:GRR1(display_short)|uniprotkb:CAT80(gene name synonym)|uniprotkb:COT2(gene name synonym)|uniprotkb:YJR090C(locus name)|uniprotkb:J1885(orf name)|uniprotkb:F-box and leucine-rich repeat protein GRR1(gene name synonym)|uniprotkb:F-box/LRR-repeat protein GRR1(gene name synonym)	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-904961|imex:IM-19845-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012623.1|sgd:S000003850|mint:P24814|dip:DIP-1626N|ensemblfungi:YJR090C(gene)|ensemblfungi:YJR090C_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0071406"(cellular response to methylmercury)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|reactome:R-SCE-163210|reactome:R-SCE-8949613	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:6BB6C46611E6F825	crc64:22BC8B35034EDDEF	comment:Shows that the F-box protein Grr1 interacts with Cdc53 but not with any of the other F-box proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:0s/WFupjCQeASvFVM+A9mSskzXY559292	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	intact-crc:ADB32A621A7AB903|rigid:WdTCMOj7SDtbKPIfNKkYGRg4HHc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39014	uniprotkb:Q12018	intact:EBI-11507|uniprotkb:D6VVN6|ensemblfungi:YIL046W	intact:EBI-4321|ensemblfungi:YDL132W|uniprotkb:D6VRL7	psi-mi:met30_yeast(display_long)|uniprotkb:YIL046W(locus name)|uniprotkb:MET30(gene name)|psi-mi:MET30(display_short)|uniprotkb:Methionine-requiring protein 30(gene name synonym)|uniprotkb:"E3 ubiquitin ligase complex SCF(Met30) subunit MET30"(gene name synonym)	psi-mi:cdc53_yeast(display_long)|uniprotkb:CDC53(gene name)|psi-mi:CDC53(display_short)|uniprotkb:YDL132W(locus name)|uniprotkb:D2190(orf name)|uniprotkb:Cullin-A(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit CDC53(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Patton et al. (1998)	pubmed:9499404|imex:IM-19845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-905483|imex:IM-19845-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YIL046W_mRNA(transcript)|ensemblfungi:YIL046W(gene)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046686"(response to cadmium ion)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|refseq:NP_012218.1|sgd:S000001308|mint:P39014|dip:DIP-1439N	dip:DIP-1234N|ensemblfungi:YDL132W(gene)|ensemblfungi:YDL132W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3O2P|rcsb pdb:3O6B|reactome:R-SCE-174113|refseq:NP_010150.1|sgd:S000002290|mint:Q12018|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	crc64:5135D4BCA2E1EB97	crc64:22BC8B35034EDDEF	comment:Shows that the F-box protein Met30 does not interact with other F-box proteins but does interact with Cdc53.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/13	2014/10/16	rogid:B138OcWsG8zW/eFMselD2pFyy5c559292	rogid:ycwncb4mcXUbeLZlAdn3jN34zsI559292	intact-crc:5FBBBACC377CFA22|rigid:aZi2RtDJzeshkpPSq3HPCr7EOKo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)