#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P13444 uniprotkb:P13444 intact:EBI-961260|uniprotkb:Q5FVU2 intact:EBI-961260|uniprotkb:Q5FVU2 psi-mi:metk1_rat(display_long)|uniprotkb:Mat1a(gene name)|psi-mi:Mat1a(display_short)|uniprotkb:Ams1(gene name synonym)|uniprotkb:Methionine adenosyltransferase 1(gene name synonym)|uniprotkb:Methionine adenosyltransferase I/III(gene name synonym) psi-mi:metk1_rat(display_long)|uniprotkb:Mat1a(gene name)|psi-mi:Mat1a(display_short)|uniprotkb:Ams1(gene name synonym)|uniprotkb:Methionine adenosyltransferase 1(gene name synonym)|uniprotkb:Methionine adenosyltransferase I/III(gene name synonym) psi-mi:"MI:0227"(reverse phase chromatography) Mingorance et al. (1997) pubmed:9202427|imex:IM-20093 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-961271|imex:IM-20093-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000287"(magnesium ion binding)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009087"(methionine catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016597"(amino acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0065003"(protein-containing complex assembly)|rgd:3050|refseq:NP_036992.2|interpro:IPR022631|interpro:IPR022630|interpro:IPR022629|interpro:IPR022628|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022636|rcsb pdb:1O90|rcsb pdb:1O92|rcsb pdb:1O93|rcsb pdb:1O9T|rcsb pdb:1QM4|reactome:R-RNO-156581|reactome:R-RNO-1614635|reactome:R-RNO-2408508 go:"GO:0000287"(magnesium ion binding)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009087"(methionine catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016597"(amino acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0065003"(protein-containing complex assembly)|rgd:3050|refseq:NP_036992.2|interpro:IPR022631|interpro:IPR022630|interpro:IPR022629|interpro:IPR022628|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022636|rcsb pdb:1O90|rcsb pdb:1O92|rcsb pdb:1O93|rcsb pdb:1O9T|rcsb pdb:1QM4|reactome:R-RNO-156581|reactome:R-RNO-1614635|reactome:R-RNO-2408508 go:"GO:0042803"(protein homodimerization activity) - - figure legend:Figs. 1 and 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/03 2014/10/16 rogid:3PEzUzhdg/EBeUT0vTuTOOSGshA10116 rogid:3PEzUzhdg/EBeUT0vTuTOOSGshA10116 intact-crc:0D54B9BD45EC7D8F|rigid:BhkwnpCjlfU0w0oK0sPUY8X7I40 false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13444 uniprotkb:P13444 intact:EBI-961260|uniprotkb:Q5FVU2 intact:EBI-961260|uniprotkb:Q5FVU2 psi-mi:metk1_rat(display_long)|uniprotkb:Mat1a(gene name)|psi-mi:Mat1a(display_short)|uniprotkb:Ams1(gene name synonym)|uniprotkb:Methionine adenosyltransferase 1(gene name synonym)|uniprotkb:Methionine adenosyltransferase I/III(gene name synonym) psi-mi:metk1_rat(display_long)|uniprotkb:Mat1a(gene name)|psi-mi:Mat1a(display_short)|uniprotkb:Ams1(gene name synonym)|uniprotkb:Methionine adenosyltransferase 1(gene name synonym)|uniprotkb:Methionine adenosyltransferase I/III(gene name synonym) psi-mi:"MI:0227"(reverse phase chromatography) Mingorance et al. (1997) pubmed:9202427|imex:IM-20093 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-961286|imex:IM-20093-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000287"(magnesium ion binding)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009087"(methionine catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016597"(amino acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0065003"(protein-containing complex assembly)|rgd:3050|refseq:NP_036992.2|interpro:IPR022631|interpro:IPR022630|interpro:IPR022629|interpro:IPR022628|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022636|rcsb pdb:1O90|rcsb pdb:1O92|rcsb pdb:1O93|rcsb pdb:1O9T|rcsb pdb:1QM4|reactome:R-RNO-156581|reactome:R-RNO-1614635|reactome:R-RNO-2408508 go:"GO:0000287"(magnesium ion binding)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009087"(methionine catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016597"(amino acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0065003"(protein-containing complex assembly)|rgd:3050|refseq:NP_036992.2|interpro:IPR022631|interpro:IPR022630|interpro:IPR022629|interpro:IPR022628|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022636|rcsb pdb:1O90|rcsb pdb:1O92|rcsb pdb:1O93|rcsb pdb:1O9T|rcsb pdb:1QM4|reactome:R-RNO-156581|reactome:R-RNO-1614635|reactome:R-RNO-2408508 go:"GO:0051289"(protein homotetramerization) - - figure legend:Fig. 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/03 2014/10/16 rogid:3PEzUzhdg/EBeUT0vTuTOOSGshA10116 rogid:3PEzUzhdg/EBeUT0vTuTOOSGshA10116 intact-crc:EE602D6715657E2D|rigid:BhkwnpCjlfU0w0oK0sPUY8X7I40 false - - 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)