#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P08839 uniprotkb:P0AA04 intact:EBI-551533|ensemblbacteria:AAC75469|ensemblbacteria:BAA16290 intact:EBI-902853|uniprotkb:P05525|uniprotkb:P07006|ensemblbacteria:AAC75468|ensemblbacteria:BAA16289 psi-mi:pt1_ecoli(display_long)|uniprotkb:Phosphotransferase system, enzyme I(gene name synonym)|uniprotkb:ptsI(gene name)|psi-mi:ptsI(display_short)|uniprotkb:b2416(locus name)|uniprotkb:JW2409(locus name) psi-mi:pthp_ecoli(display_long)|uniprotkb:ptsH(gene name)|psi-mi:ptsH(display_short)|uniprotkb:hpr(gene name synonym)|uniprotkb:b2415(locus name)|uniprotkb:Histidine-containing protein(gene name synonym)|uniprotkb:JW2408(locus name) psi-mi:"MI:0077"(nuclear magnetic resonance) Garrett et al. (1997) pubmed:9109646|imex:IM-19844 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-902902|rcsb pdb:3eza|rcsb pdb:3ezb|rcsb pdb:3eze|imex:IM-19844-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_416911.1|refseq:WP_000623140.1|dip:DIP-10603N|ensemblbacteria:AAC75469(transcript)|ensemblbacteria:b2416(gene)|ensemblbacteria:BAA16290(gene)|ensemblbacteria:BAA16290(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0008965"(phosphoenolpyruvate-protein phosphotransferase activity)|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:"GO:0016301"(kinase activity)|go:"GO:0019197"(phosphoenolpyruvate-dependent sugar phosphotransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000121(PEP-utilizing enzyme)|interpro:IPR006318(Phosphoenolpyruvate-protein phosphotransferase)|interpro:IPR008279(PEP-utilising enzyme, mobile region)|interpro:IPR008731(Phosphotransferase system, PEP-utilising enzyme, N-terminal)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018274|interpro:IPR023151|interpro:IPR024692|interpro:IPR036618|interpro:IPR036637|interpro:IPR040442|rcsb pdb:1EZA|rcsb pdb:1EZB|rcsb pdb:1EZC|rcsb pdb:1EZD|rcsb pdb:1ZYM|rcsb pdb:2EZA|rcsb pdb:2EZB|rcsb pdb:2EZC|rcsb pdb:2HWG|rcsb pdb:2KX9|rcsb pdb:2L5H|rcsb pdb:2MP0|rcsb pdb:2N5T|rcsb pdb:2XDF|rcsb pdb:3EZA|rcsb pdb:3EZB|rcsb pdb:3EZE|rcsb pdb:6V9K|rcsb pdb:6VU0 refseq:WP_000487600.1|refseq:NP_416910.1|dip:DIP-35731N|ensemblbacteria:AAC75468(transcript)|ensemblbacteria:b2415(gene)|ensemblbacteria:BAA16289(gene)|ensemblbacteria:BAA16289(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0045152"(antisigma factor binding)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|interpro:IPR000032(Phosphotransferase system, phosphocarrier HPr protein)|interpro:IPR001020(Phosphotransferase system, HPr histidine phosphorylation site)|interpro:IPR002114(Phosphotransferase system, HPr serine phosphorylation site)|interpro:IPR035895|rcsb pdb:1CM2|rcsb pdb:1CM3|rcsb pdb:1GGR|rcsb pdb:1HDN|rcsb pdb:1J6T|rcsb pdb:1OPD|rcsb pdb:1PFH|rcsb pdb:1POH|rcsb pdb:1VRC|rcsb pdb:2JEL|rcsb pdb:2LRK|rcsb pdb:2LRL|rcsb pdb:2XDF|rcsb pdb:3CCD|rcsb pdb:3EZA|rcsb pdb:3EZB|rcsb pdb:3EZE|rcsb pdb:4XWJ|rcsb pdb:5YA0|rcsb pdb:5YA1|rcsb pdb:5YA2|rcsb pdb:6KCR - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/13 2014/10/16 rogid:BwIcA0MNQT9nJLVY3IUbzEi0hig83333 rogid:PclWk4uLFrEfcs8pGZ3juGqwvzc83333 intact-crc:215938868D8C86D3|rigid:vVFs1nn3VqBH1pOzapL4DK3JjDQ false sufficient binding region:1-249 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)