#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P40096 uniprotkb:P13393 intact:EBI-11908|ensemblfungi:YER159C|uniprotkb:D3DM66 intact:EBI-19129|uniprotkb:D3DM55|ensemblfungi:YER148W psi-mi:ncb1_yeast(display_long)|uniprotkb:BUR6(gene name)|psi-mi:BUR6(display_short)|uniprotkb:NCB1(gene name synonym)|uniprotkb:Transcription repressor BUR6(gene name synonym)|uniprotkb:YER159C(locus name) psi-mi:tbp_yeast(display_long)|uniprotkb:YER148W(locus name)|uniprotkb:SPT15(gene name)|psi-mi:SPT15(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TBP1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription factor D(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Gadbois et al. (1997) pubmed:9096360|imex:IM-19048 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1111999|imex:IM-19048-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER159C(gene)|ensemblfungi:YER159C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR027116|go:"GO:0005634"(nucleus)|refseq:NP_011086.3|sgd:S000000961|mint:P40096|dip:DIP-2066N sgd:S000000950|ensemblfungi:YER148W(gene)|ensemblfungi:YER148W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070893"(transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|rcsb pdb:1NGM|rcsb pdb:1NH2|rcsb pdb:1RM1|rcsb pdb:1TBA|rcsb pdb:1TBP|rcsb pdb:1YTB|rcsb pdb:1YTF|rcsb pdb:4B0A|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6TBM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-9018519|refseq:NP_011075.3|dip:DIP-44N|mint:P13393 - crc64:27341BD250973BA7 crc64:50365FFF1D3718CE figure legend:2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/10/24 2014/10/16 rogid:80vZFpRN7MVRN9/zvGyJI4ak7gA559292 rogid:fVZPztzKW8tuxDYYpZ7ZTFlq3Do559292 intact-crc:39C97CBD6DB0A540|rigid:XGFZBCy4eBdh609aNsQWaJEQv50 false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92317 uniprotkb:P13393 intact:EBI-37723|uniprotkb:O00064|uniprotkb:P87340|uniprotkb:Q04176|uniprotkb:D6VT30|ensemblfungi:YDR397C intact:EBI-19129|uniprotkb:D3DM55|ensemblfungi:YER148W psi-mi:ncb2_yeast(display_long)|uniprotkb:NCB2(gene name)|psi-mi:NCB2(display_short)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Transcriptional repressor YDR1(gene name synonym)|uniprotkb:YDR397C(locus name) psi-mi:tbp_yeast(display_long)|uniprotkb:YER148W(locus name)|uniprotkb:SPT15(gene name)|psi-mi:SPT15(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TBP1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription factor D(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Gadbois et al. (1997) pubmed:9096360|imex:IM-19048 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1112006|imex:IM-19048-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010685.1|sgd:S000002805|dip:DIP-2067N|mint:Q92317|ensemblfungi:YDR397C(gene)|ensemblfungi:YDR397C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0045898"(regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR042225 sgd:S000000950|ensemblfungi:YER148W(gene)|ensemblfungi:YER148W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070893"(transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|rcsb pdb:1NGM|rcsb pdb:1NH2|rcsb pdb:1RM1|rcsb pdb:1TBA|rcsb pdb:1TBP|rcsb pdb:1YTB|rcsb pdb:1YTF|rcsb pdb:4B0A|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6TBM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-9018519|refseq:NP_011075.3|dip:DIP-44N|mint:P13393 - crc64:E04EB0D6F7E8D91D crc64:50365FFF1D3718CE figure legend:2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/10/24 2014/10/16 rogid:lqILVmsMA1YDORBEGe4Xp4dsBQA559292 rogid:fVZPztzKW8tuxDYYpZ7ZTFlq3Do559292 intact-crc:BA00EAF1EDB16E60|rigid:llAuobp7gfTipbzgvsQiR0e7U1k false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92317 uniprotkb:P40096 intact:EBI-37723|uniprotkb:O00064|uniprotkb:P87340|uniprotkb:Q04176|uniprotkb:D6VT30|ensemblfungi:YDR397C intact:EBI-11908|ensemblfungi:YER159C|uniprotkb:D3DM66 psi-mi:ncb2_yeast(display_long)|uniprotkb:NCB2(gene name)|psi-mi:NCB2(display_short)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Transcriptional repressor YDR1(gene name synonym)|uniprotkb:YDR397C(locus name) psi-mi:ncb1_yeast(display_long)|uniprotkb:BUR6(gene name)|psi-mi:BUR6(display_short)|uniprotkb:NCB1(gene name synonym)|uniprotkb:Transcription repressor BUR6(gene name synonym)|uniprotkb:YER159C(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Gadbois et al. (1997) pubmed:9096360|imex:IM-19048 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1112029|imex:IM-19048-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010685.1|sgd:S000002805|dip:DIP-2067N|mint:Q92317|ensemblfungi:YDR397C(gene)|ensemblfungi:YDR397C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0045898"(regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR042225 ensemblfungi:YER159C(gene)|ensemblfungi:YER159C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR027116|go:"GO:0005634"(nucleus)|refseq:NP_011086.3|sgd:S000000961|mint:P40096|dip:DIP-2066N go:"GO:0003714"(transcription corepressor activity)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II) crc64:E04EB0D6F7E8D91D crc64:27341BD250973BA7 figure legend:2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/10/24 2014/10/16 rogid:lqILVmsMA1YDORBEGe4Xp4dsBQA559292 rogid:80vZFpRN7MVRN9/zvGyJI4ak7gA559292 intact-crc:D42B8188515CB071|rigid:6ywc7Vi9829MXjnQBR0tCDLKGMM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)