#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P13393 uniprotkb:P32786 intact:EBI-19129|uniprotkb:D3DM55|ensemblfungi:YER148W intact:EBI-15986|ensemblfungi:YBL014C|uniprotkb:D6VPY6 psi-mi:tbp_yeast(display_long)|uniprotkb:YER148W(locus name)|uniprotkb:SPT15(gene name)|psi-mi:SPT15(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TBP1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription factor D(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:rrn6_yeast(display_long)|uniprotkb:RRN6(gene name)|psi-mi:RRN6(display_short)|uniprotkb:YBL0311(orf name)|uniprotkb:YBL0312(orf name)|uniprotkb:YBL014C(locus name) psi-mi:"MI:0096"(pull down) Lin et al. (1996) pubmed:8887672|imex:IM-19886 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-988493|imex:IM-19886-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000950|ensemblfungi:YER148W(gene)|ensemblfungi:YER148W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070893"(transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|rcsb pdb:1NGM|rcsb pdb:1NH2|rcsb pdb:1RM1|rcsb pdb:1TBA|rcsb pdb:1TBP|rcsb pdb:1YTB|rcsb pdb:1YTF|rcsb pdb:4B0A|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6TBM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-9018519|refseq:NP_011075.3|dip:DIP-44N|mint:P13393 refseq:NP_009539.2|sgd:S000000110|ensemblfungi:YBL014C(gene)|ensemblfungi:YBL014C_mRNA(transcript)|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR016531(RNA polymerase I-specific transcription initiation factor RRN6)|interpro:IPR019350|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6RUO|dip:DIP-1595N|mint:P32786 - crc64:50365FFF1D3718CE - figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/08/15 2014/10/16 rogid:fVZPztzKW8tuxDYYpZ7ZTFlq3Do559292 rogid:tX2a+bXx89FXRtMtu+H0TfzVYSE559292 intact-crc:DB91D9A38D6BE4F9|rigid:uzb8Wxwf7uGeRP/84zls/YVhmas false - his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P13393 uniprotkb:Q04712 intact:EBI-19129|uniprotkb:D3DM55|ensemblfungi:YER148W intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C psi-mi:tbp_yeast(display_long)|uniprotkb:YER148W(locus name)|uniprotkb:SPT15(gene name)|psi-mi:SPT15(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TBP1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription factor D(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lin et al. (1996) pubmed:8887672|imex:IM-19886 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-988509|imex:IM-19886-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000950|ensemblfungi:YER148W(gene)|ensemblfungi:YER148W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070893"(transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|rcsb pdb:1NGM|rcsb pdb:1NH2|rcsb pdb:1RM1|rcsb pdb:1TBA|rcsb pdb:1TBP|rcsb pdb:1YTB|rcsb pdb:1YTF|rcsb pdb:4B0A|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6TBM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-9018519|refseq:NP_011075.3|dip:DIP-44N|mint:P13393 refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS - crc64:50365FFF1D3718CE - figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/08/15 2014/10/16 rogid:fVZPztzKW8tuxDYYpZ7ZTFlq3Do559292 rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292 intact-crc:13B77DF9EFDF0E31|rigid:Ca6SP8x0tHKYWgwTOJy3mnPY1wg false - myc tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32786 uniprotkb:P40992 intact:EBI-15986|ensemblfungi:YBL014C|uniprotkb:D6VPY6 intact:EBI-15990|uniprotkb:D6VWF7|ensemblfungi:YJL025W psi-mi:rrn6_yeast(display_long)|uniprotkb:RRN6(gene name)|psi-mi:RRN6(display_short)|uniprotkb:YBL0311(orf name)|uniprotkb:YBL0312(orf name)|uniprotkb:YBL014C(locus name) psi-mi:rrn7_yeast(display_long)|uniprotkb:RRN7(gene name)|psi-mi:RRN7(display_short)|uniprotkb:J1273(orf name)|uniprotkb:YJL025W(locus name) psi-mi:"MI:0018"(two hybrid) Lin et al. (1996) pubmed:8887672|imex:IM-19886 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-988537|imex:IM-19886-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009539.2|sgd:S000000110|ensemblfungi:YBL014C(gene)|ensemblfungi:YBL014C_mRNA(transcript)|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR016531(RNA polymerase I-specific transcription initiation factor RRN6)|interpro:IPR019350|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6RUO|dip:DIP-1595N|mint:P32786 sgd:S000003562|refseq:NP_012509.1|ensemblfungi:YJL025W(gene)|ensemblfungi:YJL025W_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0005668"(RNA polymerase transcription factor SL1 complex)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|interpro:IPR021752|interpro:IPR033599|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73772|go:"GO:0070860"(RNA polymerase I core factor complex)|dip:DIP-1594N|mint:P40992 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/08/15 2014/10/16 rogid:tX2a+bXx89FXRtMtu+H0TfzVYSE559292 rogid:CzstXP+bmPU2KdNoEg9jlG4f7PU559292 intact-crc:6578B9BE4DD27658|rigid:lDX6t+mZ+VdJdD88QQ10UhPIEI4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32786 uniprotkb:Q04712 intact:EBI-15986|ensemblfungi:YBL014C|uniprotkb:D6VPY6 intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C psi-mi:rrn6_yeast(display_long)|uniprotkb:RRN6(gene name)|psi-mi:RRN6(display_short)|uniprotkb:YBL0311(orf name)|uniprotkb:YBL0312(orf name)|uniprotkb:YBL014C(locus name) psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short) psi-mi:"MI:0018"(two hybrid) Lin et al. (1996) pubmed:8887672|imex:IM-19886 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-988542|imex:IM-19886-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009539.2|sgd:S000000110|ensemblfungi:YBL014C(gene)|ensemblfungi:YBL014C_mRNA(transcript)|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR016531(RNA polymerase I-specific transcription initiation factor RRN6)|interpro:IPR019350|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6RUO|dip:DIP-1595N|mint:P32786 refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/08/15 2014/10/16 rogid:tX2a+bXx89FXRtMtu+H0TfzVYSE559292 rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292 intact-crc:DBC6DC7A8BF87E43|rigid:M+zfSa9r9lxkxmoJvRXVedL9T5g false mutation decreasing interaction:50-50,64-64,57-57 mutation decreasing interaction:495-495,488-488,481-481 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)