#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P49735 uniprotkb:Q26454 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 intact:EBI-175772|uniprotkb:Q9V4M5|ensemblmetazoa:FBpp0088055|ensemblmetazoa:FBpp0311783 psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:mcm4_drome(display_long)|uniprotkb:dpa(gene name)|psi-mi:dpa(display_short)|uniprotkb:CG1616(orf name)|uniprotkb:Protein disc proliferation abnormal(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Su et al. (1996) pubmed:8688561 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-872546 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N refseq:NP_477185.1|flybase:FBgn0015929|refseq:NP_001286160.1|dip:DIP-35346N|ensemblmetazoa:FBgn0015929(gene)|ensemblmetazoa:FBtr0088982(transcript)|ensemblmetazoa:FBtr0345797(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 - - - comment:High salt conditions taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 rogid:NPLqbZqr627OjOQE1CaH1sUgciI7227 intact-crc:AE74C430C0ABB880|rigid:XLeDmiuqa55f30cbWVyHqnBD/Jo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q26454 uniprotkb:P49735 intact:EBI-175772|uniprotkb:Q9V4M5|ensemblmetazoa:FBpp0088055|ensemblmetazoa:FBpp0311783 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 psi-mi:mcm4_drome(display_long)|uniprotkb:dpa(gene name)|psi-mi:dpa(display_short)|uniprotkb:CG1616(orf name)|uniprotkb:Protein disc proliferation abnormal(gene name synonym) psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Su et al. (1996) pubmed:8688561 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477185.1|flybase:FBgn0015929|refseq:NP_001286160.1|dip:DIP-35346N|ensemblmetazoa:FBgn0015929(gene)|ensemblmetazoa:FBtr0088982(transcript)|ensemblmetazoa:FBtr0345797(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N - - - comment:Low salt conditions taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:NPLqbZqr627OjOQE1CaH1sUgciI7227 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 intact-crc:DA93349D9EC3669A|rigid:bRsLhI60Vq6vnhp3E90Hm80J2fA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q26454 uniprotkb:Q9VGW6 intact:EBI-175772|uniprotkb:Q9V4M5|ensemblmetazoa:FBpp0088055|ensemblmetazoa:FBpp0311783 intact:EBI-83298|ensemblmetazoa:FBpp0081756|intact:EBI-466357|uniprotkb:P91676 psi-mi:mcm4_drome(display_long)|uniprotkb:dpa(gene name)|psi-mi:dpa(display_short)|uniprotkb:CG1616(orf name)|uniprotkb:Protein disc proliferation abnormal(gene name synonym) psi-mi:mcm5_drome(display_long)|uniprotkb:Mcm5(gene name)|psi-mi:Mcm5(display_short)|uniprotkb:CG4082(orf name)|uniprotkb:Minichromosome maintenance 5 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Su et al. (1996) pubmed:8688561 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477185.1|flybase:FBgn0015929|refseq:NP_001286160.1|dip:DIP-35346N|ensemblmetazoa:FBgn0015929(gene)|ensemblmetazoa:FBtr0088982(transcript)|ensemblmetazoa:FBtr0345797(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 ensemblmetazoa:FBgn0017577(gene)|ensemblmetazoa:FBtr0082279(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042555"(MCM complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|refseq:NP_524308.2|flybase:FBgn0017577 - - - comment:Low salt conditions taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:NPLqbZqr627OjOQE1CaH1sUgciI7227 rogid:pE+5Qt9rUBjQz997MqFx67cZ/vI7227 intact-crc:DA93349D9EC3669A|rigid:bRsLhI60Vq6vnhp3E90Hm80J2fA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)