#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P49795	uniprotkb:P08753	intact:EBI-874907|uniprotkb:Q53XN0|uniprotkb:Q8TD60|uniprotkb:A8K216|uniprotkb:E1P5G9|ensembl:ENSP00000333194|ensembl:ENSP00000378483	intact:EBI-874897|ensembl:ENSRNOP00000026710	psi-mi:rgs19_human(display_long)|uniprotkb:G-alpha-interacting protein(gene name synonym)|uniprotkb:RGS19(gene name)|psi-mi:RGS19(display_short)|uniprotkb:GAIP(gene name synonym)|uniprotkb:GNAI3IP(gene name synonym)	psi-mi:gnai3_rat(display_long)|uniprotkb:"G(i) alpha-3"(gene name synonym)|uniprotkb:Gnai3(gene name)|psi-mi:Gnai3(display_short)|uniprotkb:Gnai-3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	De et al. (1995)	pubmed:8524874	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-874930	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011526787.1|refseq:XP_011526788.1|refseq:NP_001034556.1|refseq:NP_005864.1|ensembl:ENSG00000171700(gene)|ensembl:ENST00000332298(transcript)|ensembl:ENST00000395042(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006914"(autophagy)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR036305|rcsb pdb:1CMZ|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-418597	rgd:2714|refseq:NP_037238.1|dip:DIP-608N|ensembl:ENSRNOG00000019465(gene)|ensembl:ENSRNOT00000026710(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007049"(cell cycle)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0042588"(zymogen granule)|go:"GO:0045121"(membrane raft)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051048"(negative regulation of secretion)|go:"GO:0051301"(cell division)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:6MHE|rcsb pdb:6MHF|reactome:R-RNO-170670|reactome:R-RNO-392170|reactome:R-RNO-418594|reactome:R-RNO-9009391	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/01	2014/10/16	rogid:lGw7GXTwMFo5aFKUn8B4tlkZ8rM9606	rogid:8wt4f8vunS3s8NEzedbiaTyNg4Q10116	intact-crc:83221F6D85C4FE92|rigid:Kn5Ymx+8wd8zBsdrTJZE50nqKHg	false	binding-associated region:1-195	-	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
uniprotkb:P08753	uniprotkb:P49795	intact:EBI-874897|ensembl:ENSRNOP00000026710	intact:EBI-874907|uniprotkb:Q53XN0|uniprotkb:Q8TD60|uniprotkb:A8K216|uniprotkb:E1P5G9|ensembl:ENSP00000333194|ensembl:ENSP00000378483	psi-mi:gnai3_rat(display_long)|uniprotkb:"G(i) alpha-3"(gene name synonym)|uniprotkb:Gnai3(gene name)|psi-mi:Gnai3(display_short)|uniprotkb:Gnai-3(gene name synonym)	psi-mi:rgs19_human(display_long)|uniprotkb:G-alpha-interacting protein(gene name synonym)|uniprotkb:RGS19(gene name)|psi-mi:RGS19(display_short)|uniprotkb:GAIP(gene name synonym)|uniprotkb:GNAI3IP(gene name synonym)	psi-mi:"MI:0096"(pull down)	De et al. (1995)	pubmed:8524874	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-875139	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2714|refseq:NP_037238.1|dip:DIP-608N|ensembl:ENSRNOG00000019465(gene)|ensembl:ENSRNOT00000026710(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007049"(cell cycle)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0042588"(zymogen granule)|go:"GO:0045121"(membrane raft)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051048"(negative regulation of secretion)|go:"GO:0051301"(cell division)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:6MHE|rcsb pdb:6MHF|reactome:R-RNO-170670|reactome:R-RNO-392170|reactome:R-RNO-418594|reactome:R-RNO-9009391	refseq:XP_011526787.1|refseq:XP_011526788.1|refseq:NP_001034556.1|refseq:NP_005864.1|ensembl:ENSG00000171700(gene)|ensembl:ENST00000332298(transcript)|ensembl:ENST00000395042(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006914"(autophagy)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR036305|rcsb pdb:1CMZ|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-418597	-	-	-	-	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/01	2014/10/16	rogid:8wt4f8vunS3s8NEzedbiaTyNg4Q10116	rogid:lGw7GXTwMFo5aFKUn8B4tlkZ8rM9606	intact-crc:345121FDD31D8C48|rigid:Kn5Ymx+8wd8zBsdrTJZE50nqKHg	false	35s radiolabel:?-?	binding-associated region:1-195|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P08753	uniprotkb:P49795	intact:EBI-874897|ensembl:ENSRNOP00000026710	intact:EBI-874907|uniprotkb:Q53XN0|uniprotkb:Q8TD60|uniprotkb:A8K216|uniprotkb:E1P5G9|ensembl:ENSP00000333194|ensembl:ENSP00000378483	psi-mi:gnai3_rat(display_long)|uniprotkb:"G(i) alpha-3"(gene name synonym)|uniprotkb:Gnai3(gene name)|psi-mi:Gnai3(display_short)|uniprotkb:Gnai-3(gene name synonym)	psi-mi:rgs19_human(display_long)|uniprotkb:G-alpha-interacting protein(gene name synonym)|uniprotkb:RGS19(gene name)|psi-mi:RGS19(display_short)|uniprotkb:GAIP(gene name synonym)|uniprotkb:GNAI3IP(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	De et al. (1995)	pubmed:8524874	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-875208	author score:GAI3 was found to interact strongly with GAIP - as measured by Beta-gal filter and liquid assays.	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2714|refseq:NP_037238.1|dip:DIP-608N|ensembl:ENSRNOG00000019465(gene)|ensembl:ENSRNOT00000026710(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007049"(cell cycle)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0042588"(zymogen granule)|go:"GO:0045121"(membrane raft)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051048"(negative regulation of secretion)|go:"GO:0051301"(cell division)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:6MHE|rcsb pdb:6MHF|reactome:R-RNO-170670|reactome:R-RNO-392170|reactome:R-RNO-418594|reactome:R-RNO-9009391	refseq:XP_011526787.1|refseq:XP_011526788.1|refseq:NP_001034556.1|refseq:NP_005864.1|ensembl:ENSG00000171700(gene)|ensembl:ENST00000332298(transcript)|ensembl:ENST00000395042(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006914"(autophagy)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR036305|rcsb pdb:1CMZ|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-418597	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/01	2014/10/16	rogid:8wt4f8vunS3s8NEzedbiaTyNg4Q10116	rogid:lGw7GXTwMFo5aFKUn8B4tlkZ8rM9606	intact-crc:1F30B371520EE13F|rigid:Kn5Ymx+8wd8zBsdrTJZE50nqKHg	false	-	binding-associated region:29-217	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49795	uniprotkb:P04899	intact:EBI-874907|uniprotkb:Q53XN0|uniprotkb:Q8TD60|uniprotkb:A8K216|uniprotkb:E1P5G9|ensembl:ENSP00000333194|ensembl:ENSP00000378483	intact:EBI-353997|uniprotkb:Q8IZ71|intact:EBI-2563889|uniprotkb:B4DYA0|intact:EBI-4404691|uniprotkb:Q6B6N3|uniprotkb:B3KTZ0|uniprotkb:B4E2X5|ensembl:ENSP00000312999	psi-mi:rgs19_human(display_long)|uniprotkb:G-alpha-interacting protein(gene name synonym)|uniprotkb:RGS19(gene name)|psi-mi:RGS19(display_short)|uniprotkb:GAIP(gene name synonym)|uniprotkb:GNAI3IP(gene name synonym)	psi-mi:gnai2_human(display_long)|uniprotkb:GNAI2(gene name)|psi-mi:GNAI2(display_short)|uniprotkb:GNAI2B(gene name synonym)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	De et al. (1995)	pubmed:8524874	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-875225	author score:"GAI2 was found to interact very weakly with GAIP.  Beta-gal liquid assays estimated that the interaction produced only 6% as much Beta-gal as the rgs19-gnai3 interaction (IntAct Accession:EBI-875208)"	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011526787.1|refseq:XP_011526788.1|refseq:NP_001034556.1|refseq:NP_005864.1|ensembl:ENSG00000171700(gene)|ensembl:ENST00000332298(transcript)|ensembl:ENST00000395042(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006914"(autophagy)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR036305|rcsb pdb:1CMZ|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-418597	refseq:NP_002061.1|refseq:NP_001269546.1|refseq:NP_001269549.1|refseq:NP_001269547.1|refseq:NP_001269548.1|refseq:NP_001159897.1|dip:DIP-602N|ensembl:ENSG00000114353(gene)|ensembl:ENST00000313601(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001973"(G protein-coupled adenosine receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:0030425"(dendrite)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:6D9H|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|mint:P04899	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/01	2014/10/16	rogid:lGw7GXTwMFo5aFKUn8B4tlkZ8rM9606	rogid:Mi3PAXudkdPb375bOi7luNAmUaU9606	intact-crc:369CF3BDDB78EC41|rigid:UHN8n8yDJsPTcv0+HBaiF7rwGy0	false	binding-associated region:29-217	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P08753	uniprotkb:P49795	intact:EBI-874897|ensembl:ENSRNOP00000026710	intact:EBI-874907|uniprotkb:Q53XN0|uniprotkb:Q8TD60|uniprotkb:A8K216|uniprotkb:E1P5G9|ensembl:ENSP00000333194|ensembl:ENSP00000378483	psi-mi:gnai3_rat(display_long)|uniprotkb:"G(i) alpha-3"(gene name synonym)|uniprotkb:Gnai3(gene name)|psi-mi:Gnai3(display_short)|uniprotkb:Gnai-3(gene name synonym)	psi-mi:rgs19_human(display_long)|uniprotkb:G-alpha-interacting protein(gene name synonym)|uniprotkb:RGS19(gene name)|psi-mi:RGS19(display_short)|uniprotkb:GAIP(gene name synonym)|uniprotkb:GNAI3IP(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	De et al. (1995)	pubmed:8524874	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-875257	author score:GAI3 was found to interact strongly with GAIP - as measured by Beta-gal filter and liquid assays.	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2714|refseq:NP_037238.1|dip:DIP-608N|ensembl:ENSRNOG00000019465(gene)|ensembl:ENSRNOT00000026710(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007049"(cell cycle)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0042588"(zymogen granule)|go:"GO:0045121"(membrane raft)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051048"(negative regulation of secretion)|go:"GO:0051301"(cell division)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:6MHE|rcsb pdb:6MHF|reactome:R-RNO-170670|reactome:R-RNO-392170|reactome:R-RNO-418594|reactome:R-RNO-9009391	refseq:XP_011526787.1|refseq:XP_011526788.1|refseq:NP_001034556.1|refseq:NP_005864.1|ensembl:ENSG00000171700(gene)|ensembl:ENST00000332298(transcript)|ensembl:ENST00000395042(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006914"(autophagy)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR036305|rcsb pdb:1CMZ|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-418597	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/01	2014/10/16	rogid:8wt4f8vunS3s8NEzedbiaTyNg4Q10116	rogid:lGw7GXTwMFo5aFKUn8B4tlkZ8rM9606	intact-crc:594754D375C205C5|rigid:Kn5Ymx+8wd8zBsdrTJZE50nqKHg	false	-	binding-associated region:79-206(IPR000342)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)