#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32389 uniprotkb:P39014 intact:EBI-10757|uniprotkb:D6W176 intact:EBI-11507|uniprotkb:D6VVN6|ensemblfungi:YIL046W psi-mi:met4_yeast(display_long)|uniprotkb:MET4(gene name)|psi-mi:MET4(display_short)|uniprotkb:YNL103W(locus name)|uniprotkb:N2177(orf name)|uniprotkb:Methionine-requiring protein 4(gene name synonym) psi-mi:met30_yeast(display_long)|uniprotkb:YIL046W(locus name)|uniprotkb:MET30(gene name)|psi-mi:MET30(display_short)|uniprotkb:Methionine-requiring protein 30(gene name synonym)|uniprotkb:"E3 ubiquitin ligase complex SCF(Met30) subunit MET30"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Thomas et al. (1995) pubmed:8524217|imex:IM-19842 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-889810|imex:IM-19842-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005047|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0089713"(Cbf1-Met4-Met28 complex)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0042802"(identical protein binding)|refseq:NP_014296.4|mint:P32389|dip:DIP-2241N ensemblfungi:YIL046W_mRNA(transcript)|ensemblfungi:YIL046W(gene)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046686"(response to cadmium ion)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|refseq:NP_012218.1|sgd:S000001308|mint:P39014|dip:DIP-1439N - crc64:D65745E1FA40C09D crc64:5135D4BCA2E1EB97 comment:"The inhibitory region of Met4 (AA 188-234) is necessary for the formation of the Met4-Met30 complex."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/09 2014/10/16 rogid:SpxM+SnEmiw+uQlCEGZSto/zduw559292 rogid:B138OcWsG8zW/eFMselD2pFyy5c559292 intact-crc:FCDBD4E99ACD5135|rigid:wI0BBJhBGohBhUh282FVK/ON83Y false necessary binding region:188-235 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)