#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P06784 uniprotkb:P32917 intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name) psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895358|imex:IM-19843-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784 refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917 - crc64:C8A75899CFBE8BDE crc64:0435BDA0196B2D6F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292 rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292 intact-crc:8D930A37F5C10FF7|rigid:gtEoqcBVpwl+M5VAwVak6f5qAyU false sufficient binding region:172-515(IPR000719) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23561 uniprotkb:P32917 intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895364|imex:IM-19843-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917 - crc64:E9E0DF27114EEEEF crc64:0435BDA0196B2D6F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292 intact-crc:D243B7996E82C620|rigid:E0KvwRakNEg7hYiAWsrICIO1gdo false sufficient binding region:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32917 uniprotkb:P16892 intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name) psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895373|imex:IM-19843-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917 refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635 - crc64:0435BDA0196B2D6F crc64:5117980D20A1E7E2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292 rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292 intact-crc:19A330B5FE963833|rigid:z8bRRQgHqqK7UzwqDKBKeV8YYTo false necessary binding region:240-336 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14681 uniprotkb:P32917 intact:EBI-9945|uniprotkb:Q45U43|uniprotkb:D6VUH8|ensemblfungi:YGR040W intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W psi-mi:kss1_yeast(display_long)|uniprotkb:KSS1(gene name)|psi-mi:KSS1(display_short)|uniprotkb:Kinase suppressor of SST2(gene name synonym)|uniprotkb:YGR040W(locus name) psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895378|imex:IM-19843-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003272|ensemblfungi:YGR040W(gene)|ensemblfungi:YGR040W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-111995|reactome:R-SCE-112411|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635|refseq:NP_011554.3|reactome:R-SCE-112409|reactome:R-SCE-3371453|reactome:R-SCE-445144|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|dip:DIP-60N|reactome:R-SCE-170968|reactome:R-SCE-450341 refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917 - crc64:5FA42161B5FD51B5 crc64:0435BDA0196B2D6F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:xE1y1jku+iWy4xzv9wUCul1AFZs559292 rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292 intact-crc:C273C0D3A3495A2D|rigid:5VKYHxQFP2dDZhVoJBc2LjH70Js false sufficient binding region:240-336 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06784 uniprotkb:P16892 intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name) psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895383|imex:IM-19843-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784 refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635 - crc64:C8A75899CFBE8BDE crc64:5117980D20A1E7E2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292 rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292 intact-crc:809A8049D98F2492|rigid:yKqt5c73FuqWsnSqFRluKQz18Xw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14681 uniprotkb:P06784 intact:EBI-9945|uniprotkb:Q45U43|uniprotkb:D6VUH8|ensemblfungi:YGR040W intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W psi-mi:kss1_yeast(display_long)|uniprotkb:KSS1(gene name)|psi-mi:KSS1(display_short)|uniprotkb:Kinase suppressor of SST2(gene name synonym)|uniprotkb:YGR040W(locus name) psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895389|imex:IM-19843-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003272|ensemblfungi:YGR040W(gene)|ensemblfungi:YGR040W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-111995|reactome:R-SCE-112411|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635|refseq:NP_011554.3|reactome:R-SCE-112409|reactome:R-SCE-3371453|reactome:R-SCE-445144|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|dip:DIP-60N|reactome:R-SCE-170968|reactome:R-SCE-450341 refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784 - crc64:5FA42161B5FD51B5 crc64:C8A75899CFBE8BDE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:xE1y1jku+iWy4xzv9wUCul1AFZs559292 rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292 intact-crc:136CA7CE5275FE62|rigid:v9VALaELwEARboEE7iHaBr1KUi0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16892 uniprotkb:P23561 intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name) psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895394|imex:IM-19843-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635 refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 - crc64:5117980D20A1E7E2 crc64:E9E0DF27114EEEEF full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 intact-crc:F0B0B35A0DFCA032|rigid:f4thJo+bgcgLi5xi9+ovTy7bTZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14681 uniprotkb:P23561 intact:EBI-9945|uniprotkb:Q45U43|uniprotkb:D6VUH8|ensemblfungi:YGR040W intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W psi-mi:kss1_yeast(display_long)|uniprotkb:KSS1(gene name)|psi-mi:KSS1(display_short)|uniprotkb:Kinase suppressor of SST2(gene name synonym)|uniprotkb:YGR040W(locus name) psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895399|imex:IM-19843-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003272|ensemblfungi:YGR040W(gene)|ensemblfungi:YGR040W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-111995|reactome:R-SCE-112411|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635|refseq:NP_011554.3|reactome:R-SCE-112409|reactome:R-SCE-3371453|reactome:R-SCE-445144|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|dip:DIP-60N|reactome:R-SCE-170968|reactome:R-SCE-450341 refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 - crc64:5FA42161B5FD51B5 crc64:E9E0DF27114EEEEF full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:xE1y1jku+iWy4xzv9wUCul1AFZs559292 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 intact-crc:88FA47D552E820BF|rigid:GyNr48SPdaWLSDX9oZCStH9tvII false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23561 uniprotkb:P23561 intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895411|imex:IM-19843-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 go:"GO:0042803"(protein homodimerization activity) crc64:E9E0DF27114EEEEF crc64:E9E0DF27114EEEEF full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 intact-crc:F18355F663172C2A|rigid:MK2eAtJNU//loddztWugTS3I2Tc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32917 uniprotkb:P23561 intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name) psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895417|imex:IM-19843-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917 refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 - crc64:0435BDA0196B2D6F crc64:E9E0DF27114EEEEF full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 intact-crc:15F6137FE4881597|rigid:E0KvwRakNEg7hYiAWsrICIO1gdo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23561 uniprotkb:P16892 intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895428|imex:IM-19843-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635 - crc64:E9E0DF27114EEEEF crc64:5117980D20A1E7E2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292 intact-crc:84814CEE2D6B35A5|rigid:f4thJo+bgcgLi5xi9+ovTy7bTZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23561 uniprotkb:P14681 intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W intact:EBI-9945|uniprotkb:Q45U43|uniprotkb:D6VUH8|ensemblfungi:YGR040W psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:kss1_yeast(display_long)|uniprotkb:KSS1(gene name)|psi-mi:KSS1(display_short)|uniprotkb:Kinase suppressor of SST2(gene name synonym)|uniprotkb:YGR040W(locus name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895433|imex:IM-19843-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 sgd:S000003272|ensemblfungi:YGR040W(gene)|ensemblfungi:YGR040W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-111995|reactome:R-SCE-112411|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635|refseq:NP_011554.3|reactome:R-SCE-112409|reactome:R-SCE-3371453|reactome:R-SCE-445144|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|dip:DIP-60N|reactome:R-SCE-170968|reactome:R-SCE-450341 - crc64:E9E0DF27114EEEEF crc64:5FA42161B5FD51B5 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 rogid:xE1y1jku+iWy4xzv9wUCul1AFZs559292 intact-crc:5617E6F4B2342125|rigid:GyNr48SPdaWLSDX9oZCStH9tvII false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32917 uniprotkb:P06784 intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name) psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895474|imex:IM-19843-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917 refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784 - crc64:0435BDA0196B2D6F crc64:C8A75899CFBE8BDE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292 rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292 intact-crc:86A6900293C91724|rigid:gtEoqcBVpwl+M5VAwVak6f5qAyU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06784 uniprotkb:P16892 intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name) psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895490|imex:IM-19843-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784 refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635 - crc64:C8A75899CFBE8BDE crc64:5117980D20A1E7E2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292 rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292 intact-crc:1968E1E76B1E863D|rigid:yKqt5c73FuqWsnSqFRluKQz18Xw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06784 uniprotkb:P14681 intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W intact:EBI-9945|uniprotkb:Q45U43|uniprotkb:D6VUH8|ensemblfungi:YGR040W psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name) psi-mi:kss1_yeast(display_long)|uniprotkb:KSS1(gene name)|psi-mi:KSS1(display_short)|uniprotkb:Kinase suppressor of SST2(gene name synonym)|uniprotkb:YGR040W(locus name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895504|imex:IM-19843-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784 sgd:S000003272|ensemblfungi:YGR040W(gene)|ensemblfungi:YGR040W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-111995|reactome:R-SCE-112411|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635|refseq:NP_011554.3|reactome:R-SCE-112409|reactome:R-SCE-3371453|reactome:R-SCE-445144|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|dip:DIP-60N|reactome:R-SCE-170968|reactome:R-SCE-450341 - crc64:C8A75899CFBE8BDE crc64:5FA42161B5FD51B5 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292 rogid:xE1y1jku+iWy4xzv9wUCul1AFZs559292 intact-crc:1ABB323562658B01|rigid:v9VALaELwEARboEE7iHaBr1KUi0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32917 uniprotkb:P06784 intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name) psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name) psi-mi:"MI:0018"(two hybrid) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895510|imex:IM-19843-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917 refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784 - crc64:0435BDA0196B2D6F crc64:C8A75899CFBE8BDE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292 rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292 intact-crc:395FD67CE629628B|rigid:gtEoqcBVpwl+M5VAwVak6f5qAyU false necessary binding region:586-917 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32917 uniprotkb:P16892 intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name) psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name) psi-mi:"MI:0096"(pull down) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-895631|imex:IM-19843-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917 refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635 - crc64:0435BDA0196B2D6F crc64:5117980D20A1E7E2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292 rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292 intact-crc:B1D6C5AA1182190D|rigid:Gfe5XN5WcwKi4ozpFcq2XeBFJtY false glutathione s tranferase tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32917 uniprotkb:P23561 intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name) psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:"MI:0096"(pull down) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-895631|imex:IM-19843-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917 refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 - crc64:0435BDA0196B2D6F crc64:E9E0DF27114EEEEF full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 intact-crc:B1D6C5AA1182190D|rigid:Gfe5XN5WcwKi4ozpFcq2XeBFJtY false glutathione s tranferase tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P16892 uniprotkb:P32917 intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name) psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name) psi-mi:"MI:0096"(pull down) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895654|imex:IM-19843-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635 refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917 - crc64:5117980D20A1E7E2 crc64:0435BDA0196B2D6F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292 rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292 intact-crc:2C725BD3014A6857|rigid:z8bRRQgHqqK7UzwqDKBKeV8YYTo false ha tag:?-? glutathione s tranferase tag:?-?|necessary binding region:143-309 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32917 uniprotkb:P23561 intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name) psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:"MI:0096"(pull down) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895663|imex:IM-19843-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917 refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 - crc64:0435BDA0196B2D6F crc64:E9E0DF27114EEEEF comment:Kinase activity of Ste11 not required for this interaction|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 intact-crc:F292B2938F348F56|rigid:E0KvwRakNEg7hYiAWsrICIO1gdo false glutathione s tranferase tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32917 uniprotkb:P06784 intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name) psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name) psi-mi:"MI:0096"(pull down) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895683|imex:IM-19843-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917 refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784 - crc64:0435BDA0196B2D6F crc64:C8A75899CFBE8BDE comment:Ste5 associates primarily with an underphosphorylated form of Ste7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292 rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292 intact-crc:A38A132BC6049244|rigid:gtEoqcBVpwl+M5VAwVak6f5qAyU false glutathione s tranferase tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32917 uniprotkb:P06784 intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name) psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name) psi-mi:"MI:0096"(pull down) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-895700|imex:IM-19843-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917 refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784 - crc64:0435BDA0196B2D6F crc64:C8A75899CFBE8BDE comment:Ste5 associates primarily with an underphosphorylated form of Ste7, greater levels of Ste7 associate with Ste5 in the presence of kinase-dead Ste11|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292 rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292 intact-crc:FB73E24241186F5D|rigid:e+N7PmHPwZdrg3oY58vnXuXnzsg false glutathione s tranferase tag:?-?|sufficient binding region:24-142,310-917 myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32917 uniprotkb:P23561 intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name) psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:"MI:0096"(pull down) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-895700|imex:IM-19843-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917 refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 - crc64:0435BDA0196B2D6F crc64:E9E0DF27114EEEEF comment:Ste5 associates primarily with an underphosphorylated form of Ste7, greater levels of Ste7 associate with Ste5 in the presence of kinase-dead Ste11|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 intact-crc:FB73E24241186F5D|rigid:e+N7PmHPwZdrg3oY58vnXuXnzsg false glutathione s tranferase tag:?-?|sufficient binding region:24-142,310-917 myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P16892 uniprotkb:P23561 intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name) psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:"MI:0029"(cosedimentation through density gradient) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895753|imex:IM-19843-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635 refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 - crc64:5117980D20A1E7E2 crc64:E9E0DF27114EEEEF full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 intact-crc:54253C554BDE821D|rigid:rKgxx7xOJHSull/+hQC29+K5+pI false - myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P16892 uniprotkb:P32917 intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name) psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name) psi-mi:"MI:0029"(cosedimentation through density gradient) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895753|imex:IM-19843-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635 refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917 - crc64:5117980D20A1E7E2 crc64:0435BDA0196B2D6F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292 rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292 intact-crc:54253C554BDE821D|rigid:rKgxx7xOJHSull/+hQC29+K5+pI false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P16892 uniprotkb:P06784 intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name) psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name) psi-mi:"MI:0029"(cosedimentation through density gradient) Choi et al. (1994) pubmed:8062390|imex:IM-19843|mint:MINT-5220710 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-895753|imex:IM-19843-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635 refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784 - crc64:5117980D20A1E7E2 crc64:C8A75899CFBE8BDE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/10 2014/10/16 rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292 rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292 intact-crc:54253C554BDE821D|rigid:rKgxx7xOJHSull/+hQC29+K5+pI false - myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)