#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P23560 uniprotkb:P20783 intact:EBI-1026003|uniprotkb:Q9BYY7|uniprotkb:Q9UC24|uniprotkb:A7LA85|uniprotkb:A7LA92|uniprotkb:Q598Q1|uniprotkb:Q6DN19|uniprotkb:Q6YNR2|uniprotkb:Q6YNR3|uniprotkb:D3DQZ2|ensembl:ENSP00000349084|ensembl:ENSP00000379302|ensembl:ENSP00000379305|ensembl:ENSP00000379307|ensembl:ENSP00000389345|ensembl:ENSP00000400502|ensembl:ENSP00000432035|ensembl:ENSP00000432376|ensembl:ENSP00000432727|ensembl:ENSP00000435564|ensembl:ENSP00000435805|ensembl:ENSP00000437138 intact:EBI-1025994|uniprotkb:Q6FH50|ensembl:ENSP00000328738|uniprotkb:B7Z1T5 psi-mi:bdnf_human(display_long)|uniprotkb:Abrineurin(gene name synonym)|uniprotkb:BDNF(gene name)|psi-mi:BDNF(display_short) psi-mi:ntf3_human(display_long)|uniprotkb:Neurotrophic factor(gene name synonym)|uniprotkb:HDNF(gene name synonym)|uniprotkb:Nerve growth factor 2(gene name synonym)|uniprotkb:NTF3(gene name)|psi-mi:NTF3(display_short) psi-mi:"MI:0114"(x-ray crystallography) Robinson et al. (1995) pubmed:7703225|mint:MINT-5220530 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1026019|rcsb pdb:1BND - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137277.1|refseq:NP_001137278.1|refseq:NP_001137279.1|refseq:NP_001137280.1|refseq:NP_001137281.1|refseq:NP_001137282.1|refseq:NP_001137283.1|refseq:NP_001137284.1|refseq:NP_001137285.1|refseq:NP_001137286.1|refseq:NP_001137288.1|refseq:NP_001700.2|refseq:NP_733927.1|refseq:NP_733928.1|refseq:NP_733929.1|refseq:NP_733930.1|refseq:NP_733931.1|refseq:XP_011518582.1|ensembl:ENST00000439476(transcript)|ensembl:ENST00000525528(transcript)|ensembl:ENST00000525950(transcript)|ensembl:ENST00000530861(transcript)|ensembl:ENST00000532997(transcript)|ensembl:ENST00000533131(transcript)|ensembl:ENST00000533246(transcript)|go:"GO:0005163"(nerve growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007416"(synapse assembly)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007613"(memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008083"(growth factor activity)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016607"(nuclear speck)|go:"GO:0021675"(nerve development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031547"(brain-derived neurotrophic factor receptor signaling pathway)|go:"GO:0031550"(positive regulation of brain-derived neurotrophic factor receptor signaling pathway)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048668"(collateral sprouting)|go:"GO:0048672"(positive regulation of collateral sprouting)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002072(Nerve growth factor)|interpro:IPR019846|interpro:IPR020408|interpro:IPR020430|interpro:IPR029034|rcsb pdb:1B8M|rcsb pdb:1BND|reactome:R-HSA-9022702|reactome:R-HSA-9024909|reactome:R-HSA-9026519|reactome:R-HSA-9026527|reactome:R-HSA-9028335|reactome:R-HSA-9028731|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-9032845|ensembl:ENSG00000176697(gene)|ensembl:ENST00000356660(transcript)|ensembl:ENST00000395978(transcript)|ensembl:ENST00000395981(transcript)|ensembl:ENST00000395983(transcript)|ensembl:ENST00000418212(transcript)|dip:DIP-5719N refseq:NP_001096124.1|refseq:NP_002518.1|refseq:XP_011519265.1|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR002072(Nerve growth factor)|interpro:IPR015578(Neurotrophin-3)|interpro:IPR019846|interpro:IPR020408|interpro:IPR029034|rcsb pdb:1B8K|rcsb pdb:1BND|rcsb pdb:1NT3|rcsb pdb:3BUK|reactome:R-HSA-9025046|reactome:R-HSA-9034013|reactome:R-HSA-9034015|reactome:R-HSA-9034793|reactome:R-HSA-9034864|reactome:R-HSA-9603381|ensembl:ENSG00000185652(gene)|ensembl:ENST00000331010(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005163"(nerve growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007399"(nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007613"(memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021675"(nerve development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|dip:DIP-346N - - - assembly:monomeric|3d-resolution:2.3A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:ViQaPrafdzqN17LGUTSwDrBT/bU9606 rogid:E2ZTORtat5r2YRbDmEB3Qt+ojMQ9606 intact-crc:0609693268910B1C|rigid:Lml7/4JlasjiStT4FjGPyO081P8 false sufficient binding region:129-247 sufficient binding region:139-257 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)