#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q62950	uniprotkb:O35826	intact:EBI-7109419|ensembl:ENSRNOP00000063671|uniprotkb:P70546|intact:MINT-4051102	intact:EBI-7109445|ensembl:ENSRNOP00000019532|intact:MINT-4051080	psi-mi:dpyl1_rat(display_long)|uniprotkb:Crmp1(gene name)|psi-mi:Crmp1(display_short)|uniprotkb:Dpysl1(gene name synonym)|uniprotkb:Collapsin response mediator protein 1(gene name synonym)|uniprotkb:Inactive dihydropyrimidinase(gene name synonym)	psi-mi:glcne_rat(display_long)|uniprotkb:Gne(gene name)|psi-mi:Gne(display_short)|uniprotkb:Glcne(gene name synonym)|uniprotkb:UDP-GlcNAc-2-epimerase/ManAc kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Weidemann et al. (2006)	pubmed:17118363|imex:IM-11431|mint:MINT-5219362	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7109412|mint:MINT-3974621|imex:IM-11431-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000004781(gene)|ensembl:ENSRNOT00000065334(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007411"(axon guidance)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031005"(filamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0048666"(neuron development)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1904530"(negative regulation of actin filament binding)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030624|interpro:IPR032466|mint:Q62950|reactome:R-RNO-399956|refseq:NP_037064.1|rgd:2407|mint:MINT-3974622(identity)	refseq:XP_006238070.1|refseq:XP_006238071.1|ensembl:ENSRNOG00000014365(gene)|ensembl:ENSRNOT00000019532(transcript)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006045"(N-acetylglucosamine biosynthetic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0008761"(UDP-N-acetylglucosamine 2-epimerase activity)|go:"GO:0009384"(N-acylmannosamine kinase activity)|go:"GO:0046380"(N-acetylneuraminate biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000600(ROK)|interpro:IPR003331(UDP-N-acetylglucosamine 2-epimerase)|interpro:IPR020004|interpro:IPR043129|mint:O35826|reactome:R-RNO-4085001|refseq:NP_446217.1|rgd:69239|mint:MINT-3974630(identity)	-	function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration|comment:mint	comment:mint|function:"Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. Plays an essential role in early development"	figure legend:F4C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells)	-	2006/12/18	2014/10/16	rogid:7low1NeCgJsFO6tv/Jic3nBec4g10116	rogid:EapDfHP6dfouXdCPhGo4WM8jitI10116	intact-crc:A655F17DE1977BFA|rigid:GWgNeQfb+vLONjydVOiZ9thMweQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:O35826	uniprotkb:Q05516	intact:EBI-7109445|ensembl:ENSRNOP00000019532|intact:MINT-4051080	intact:EBI-711925|ensembl:ENSP00000338157|ensembl:ENSP00000376721|ensembl:ENSP00000506794|ensembl:ENSP00000506894|ensembl:ENSP00000506924|ensembl:ENSP00000506953|ensembl:ENSP00000507788|ensembl:ENSP00000508351|uniprotkb:Q8TAL4	psi-mi:glcne_rat(display_long)|uniprotkb:Gne(gene name)|psi-mi:Gne(display_short)|uniprotkb:Glcne(gene name synonym)|uniprotkb:UDP-GlcNAc-2-epimerase/ManAc kinase(gene name synonym)	psi-mi:zbt16_human(display_long)|uniprotkb:Zinc finger protein PLZF(gene name synonym)|uniprotkb:Promyelocytic leukemia zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 145(gene name synonym)|uniprotkb:ZBTB16(gene name)|psi-mi:ZBTB16(display_short)|uniprotkb:PLZF(gene name synonym)|uniprotkb:ZNF145(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Weidemann et al. (2006)	pubmed:17118363|imex:IM-11431|mint:MINT-5219362	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7109521|mint:MINT-3974447|imex:IM-11431-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006238070.1|refseq:XP_006238071.1|ensembl:ENSRNOG00000014365(gene)|ensembl:ENSRNOT00000019532(transcript)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006045"(N-acetylglucosamine biosynthetic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0008761"(UDP-N-acetylglucosamine 2-epimerase activity)|go:"GO:0009384"(N-acylmannosamine kinase activity)|go:"GO:0046380"(N-acetylneuraminate biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000600(ROK)|interpro:IPR003331(UDP-N-acetylglucosamine 2-epimerase)|interpro:IPR020004|interpro:IPR043129|mint:O35826|reactome:R-RNO-4085001|refseq:NP_446217.1|rgd:69239|mint:MINT-3974448(identity)	ensembl:ENSG00000109906(gene)|ensembl:ENST00000335953(transcript)|ensembl:ENST00000392996(transcript)|ensembl:ENST00000682278(transcript)|ensembl:ENST00000682697(transcript)|ensembl:ENST00000682971(transcript)|ensembl:ENST00000683318(transcript)|ensembl:ENST00000683554(transcript)|ensembl:ENST00000684295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001823"(mesonephros development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0061036"(positive regulation of cartilage development)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q05516|rcsb pdb:1BUO|rcsb pdb:1CS3|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001018011.1|refseq:NP_005997.2|refseq:XP_016873746.1|refseq:XP_016873747.1|refseq:XP_016873748.1|dip:DIP-2654N|mint:MINT-3974449(identity)	-	comment:mint|function:"Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. Plays an essential role in early development"	-	figure legend:T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/12/18	2014/10/16	rogid:EapDfHP6dfouXdCPhGo4WM8jitI10116	rogid:wJmkU9GC3S18VXyYd8asd+hN+yU9606	intact-crc:DD18221318931B60|rigid:uJfQw2sEfmgOMThWDKl0cppOJC4	false	tag:?-?(MINT-3974453)	binding-associated region:380-673(MINT-3974464)|tag:?-?(MINT-3974459)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O35826	uniprotkb:Q14194	intact:EBI-7109445|ensembl:ENSRNOP00000019532|intact:MINT-4051080	intact:EBI-473101|uniprotkb:Q4W5F1|uniprotkb:Q13024|uniprotkb:Q96TC8|ensembl:ENSP00000380987|uniprotkb:A0EJG6	psi-mi:glcne_rat(display_long)|uniprotkb:Gne(gene name)|psi-mi:Gne(display_short)|uniprotkb:Glcne(gene name synonym)|uniprotkb:UDP-GlcNAc-2-epimerase/ManAc kinase(gene name synonym)	psi-mi:dpyl1_human(display_long)|uniprotkb:CRMP1(gene name)|psi-mi:CRMP1(display_short)|uniprotkb:DPYSL1(gene name synonym)|uniprotkb:Collapsin response mediator protein 1(gene name synonym)|uniprotkb:ULIP3(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 3(gene name synonym)|uniprotkb:Inactive dihydropyrimidinase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Weidemann et al. (2006)	pubmed:17118363|imex:IM-11431|mint:MINT-5219362	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7109600|mint:MINT-3974529|imex:IM-11431-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006238070.1|refseq:XP_006238071.1|ensembl:ENSRNOG00000014365(gene)|ensembl:ENSRNOT00000019532(transcript)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006045"(N-acetylglucosamine biosynthetic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0008761"(UDP-N-acetylglucosamine 2-epimerase activity)|go:"GO:0009384"(N-acylmannosamine kinase activity)|go:"GO:0046380"(N-acetylneuraminate biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000600(ROK)|interpro:IPR003331(UDP-N-acetylglucosamine 2-epimerase)|interpro:IPR020004|interpro:IPR043129|mint:O35826|reactome:R-RNO-4085001|refseq:NP_446217.1|rgd:69239|mint:MINT-3974537(identity)	refseq:NP_001304.1|refseq:NP_001275590.1|refseq:NP_001275591.1|go:"GO:0031005"(filamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:1904530"(negative regulation of actin filament binding)|interpro:IPR006680(Amidohydrolase 1)|go:"GO:0030496"(midbody)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030624|interpro:IPR032466|mint:Q14194|rcsb pdb:4B3Z|reactome:R-HSA-399956|ensembl:ENSG00000072832(gene)|ensembl:ENST00000397890(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030426"(growth cone)|refseq:NP_001014809.1|mint:MINT-3974530(identity)	-	comment:mint|function:"Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. Plays an essential role in early development"	-	figure legend:T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/12/18	2014/10/16	rogid:EapDfHP6dfouXdCPhGo4WM8jitI10116	rogid:54400VvxFWldohY2QhArAEJ23cI9606	intact-crc:DC7FB3998D763565|rigid:/B3cnoDd0KzN+CYUj0DwN3xIt4Q	false	tag:?-?(MINT-3974538)|binding-associated region:407-722(MINT-3974544)	binding-associated region:390-572(MINT-3974535)|tag:?-?(MINT-3974531)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O35826	uniprotkb:Q5UIP0	intact:EBI-7109445|ensembl:ENSRNOP00000019532|intact:MINT-4051080	intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181	psi-mi:glcne_rat(display_long)|uniprotkb:Gne(gene name)|psi-mi:Gne(display_short)|uniprotkb:Glcne(gene name synonym)|uniprotkb:UDP-GlcNAc-2-epimerase/ManAc kinase(gene name synonym)	psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Weidemann et al. (2006)	pubmed:17118363|imex:IM-11431|mint:MINT-5219362	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7109578|mint:MINT-3974467|imex:IM-11431-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006238070.1|refseq:XP_006238071.1|ensembl:ENSRNOG00000014365(gene)|ensembl:ENSRNOT00000019532(transcript)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006045"(N-acetylglucosamine biosynthetic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0008761"(UDP-N-acetylglucosamine 2-epimerase activity)|go:"GO:0009384"(N-acylmannosamine kinase activity)|go:"GO:0046380"(N-acetylneuraminate biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000600(ROK)|interpro:IPR003331(UDP-N-acetylglucosamine 2-epimerase)|interpro:IPR020004|interpro:IPR043129|mint:O35826|reactome:R-RNO-4085001|refseq:NP_446217.1|rgd:69239|mint:MINT-3974476(identity)	go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1|mint:MINT-3974468(identity)	-	comment:mint|function:"Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. Plays an essential role in early development"	-	figure legend:T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/12/18	2014/10/16	rogid:EapDfHP6dfouXdCPhGo4WM8jitI10116	rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606	intact-crc:D9974B9F8C4F61BF|rigid:kkrxSkNEdn8tSOeGPACY4ynC0EI	false	tag:?-?(MINT-3974479)	binding-associated region:455-739(MINT-3974469)|tag:?-?(MINT-3974473)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O35826	uniprotkb:Q9HCM3	intact:EBI-7109445|ensembl:ENSRNOP00000019532|intact:MINT-4051080	intact:EBI-311350|intact:EBI-725593|uniprotkb:Q5BJD6|uniprotkb:Q8IY15|uniprotkb:Q9H0M3|uniprotkb:B6HY55|uniprotkb:B6HY56|uniprotkb:B6HY58|uniprotkb:B6HY60|uniprotkb:B6HY61|uniprotkb:B6HY62|uniprotkb:B6HY63|uniprotkb:B6HY64|uniprotkb:B6HY65|uniprotkb:B6HY66|intact:EBI-28967506|ensembl:ENSP00000416040	psi-mi:glcne_rat(display_long)|uniprotkb:Gne(gene name)|psi-mi:Gne(display_short)|uniprotkb:Glcne(gene name synonym)|uniprotkb:UDP-GlcNAc-2-epimerase/ManAc kinase(gene name synonym)	psi-mi:k1549_human(display_long)|uniprotkb:KIAA1549(gene name)|psi-mi:KIAA1549(display_short)	psi-mi:"MI:0018"(two hybrid)	Weidemann et al. (2006)	pubmed:17118363|imex:IM-11431|mint:MINT-5219362	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7109683|mint:MINT-3974569|imex:IM-11431-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006238070.1|refseq:XP_006238071.1|ensembl:ENSRNOG00000014365(gene)|ensembl:ENSRNOT00000019532(transcript)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006045"(N-acetylglucosamine biosynthetic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0008761"(UDP-N-acetylglucosamine 2-epimerase activity)|go:"GO:0009384"(N-acylmannosamine kinase activity)|go:"GO:0046380"(N-acetylneuraminate biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000600(ROK)|interpro:IPR003331(UDP-N-acetylglucosamine 2-epimerase)|interpro:IPR020004|interpro:IPR043129|mint:O35826|reactome:R-RNO-4085001|refseq:NP_446217.1|rgd:69239|mint:MINT-3974570(identity)	ensembl:ENSP00000416040|ensembl:ENST00000440172|ensembl:ENSP00000406661|refseq:NP_001158137.1|refseq:NP_065961.2|ensembl:ENSG00000122778(gene)|ensembl:ENST00000422774(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032391"(photoreceptor connecting cilium)|interpro:IPR024606|mint:Q9HCM3|reactome:R-HSA-6802952|mint:MINT-3974578(identity)	-	comment:mint|function:"Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. Plays an essential role in early development"	-	figure legend:T1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/12/18	2014/10/16	rogid:EapDfHP6dfouXdCPhGo4WM8jitI10116	rogid:507cC5RUCdmAeqF2NCNNYngV5qI9606	intact-crc:42D717FEAFD546B5|rigid:6jWmdYY5SWhoEnuAGjEwuWgnfCk	false	binding-associated region:407-722(MINT-3974575)|tag:?-?(MINT-3974571)	tag:?-?(MINT-3974579)|binding-associated region:77-186(MINT-3974583)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O35826	uniprotkb:Q05516	intact:EBI-7109445|ensembl:ENSRNOP00000019532|intact:MINT-4051080	intact:EBI-711925|ensembl:ENSP00000338157|ensembl:ENSP00000376721|ensembl:ENSP00000506794|ensembl:ENSP00000506894|ensembl:ENSP00000506924|ensembl:ENSP00000506953|ensembl:ENSP00000507788|ensembl:ENSP00000508351|uniprotkb:Q8TAL4	psi-mi:glcne_rat(display_long)|uniprotkb:Gne(gene name)|psi-mi:Gne(display_short)|uniprotkb:Glcne(gene name synonym)|uniprotkb:UDP-GlcNAc-2-epimerase/ManAc kinase(gene name synonym)	psi-mi:zbt16_human(display_long)|uniprotkb:Zinc finger protein PLZF(gene name synonym)|uniprotkb:Promyelocytic leukemia zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 145(gene name synonym)|uniprotkb:ZBTB16(gene name)|psi-mi:ZBTB16(display_short)|uniprotkb:PLZF(gene name synonym)|uniprotkb:ZNF145(gene name synonym)	psi-mi:"MI:0096"(pull down)	Weidemann et al. (2006)	pubmed:17118363|imex:IM-11431|mint:MINT-5219362	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7109720|mint:MINT-3974597|imex:IM-11431-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006238070.1|refseq:XP_006238071.1|ensembl:ENSRNOG00000014365(gene)|ensembl:ENSRNOT00000019532(transcript)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006045"(N-acetylglucosamine biosynthetic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0008761"(UDP-N-acetylglucosamine 2-epimerase activity)|go:"GO:0009384"(N-acylmannosamine kinase activity)|go:"GO:0046380"(N-acetylneuraminate biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000600(ROK)|interpro:IPR003331(UDP-N-acetylglucosamine 2-epimerase)|interpro:IPR020004|interpro:IPR043129|mint:O35826|reactome:R-RNO-4085001|refseq:NP_446217.1|rgd:69239|mint:MINT-3974598(identity)	ensembl:ENSG00000109906(gene)|ensembl:ENST00000335953(transcript)|ensembl:ENST00000392996(transcript)|ensembl:ENST00000682278(transcript)|ensembl:ENST00000682697(transcript)|ensembl:ENST00000682971(transcript)|ensembl:ENST00000683318(transcript)|ensembl:ENST00000683554(transcript)|ensembl:ENST00000684295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001823"(mesonephros development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0061036"(positive regulation of cartilage development)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q05516|rcsb pdb:1BUO|rcsb pdb:1CS3|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001018011.1|refseq:NP_005997.2|refseq:XP_016873746.1|refseq:XP_016873747.1|refseq:XP_016873748.1|dip:DIP-2654N|mint:MINT-3974604(identity)	-	comment:mint|function:"Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. Plays an essential role in early development"	-	figure legend:F3|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf900)|taxid:7108(Spodoptera frugiperda)	-	2006/12/18	2014/10/16	rogid:EapDfHP6dfouXdCPhGo4WM8jitI10116	rogid:wJmkU9GC3S18VXyYd8asd+hN+yU9606	intact-crc:62F2DA93F077B9B3|rigid:uJfQw2sEfmgOMThWDKl0cppOJC4	false	his tag:?-?(MINT-3974601)	glutathione s tranferase tag:?-?(MINT-3974609)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)