#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P20963	uniprotkb:P20963	intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782	intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782	psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym)	psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Call et al. (2006)	imex:IM-11994|pubmed:17055436	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1165728|imex:IM-11994-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N	refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N	rcsb pdb:2HAC(primary-reference)|go:"GO:0042803"(protein homodimerization activity)	-	-	figure legend:2, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/15	2014/10/16	rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606	rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606	intact-crc:9CCE0E0BD60CFFE8|rigid:qkUh2+KHSCaa8otA6CtuT9Y+CrQ	false	sufficient binding region:28-60|biological feature:32-32	sufficient binding region:28-60|15n label:?-?|2h label:?-?|biological feature:32-32	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20963	uniprotkb:P20963	intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782	intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782	psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym)	psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Call et al. (2006)	imex:IM-11994|pubmed:17055436	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1165817|imex:IM-11994-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N	refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/15	2014/10/16	rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606	rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606	intact-crc:3316958EE43033A0|rigid:QWVTfdcrClci4o72YbHfGwcsOTs	false	35s radiolabel:?-?|mutation decreasing interaction:36-36|mutation decreasing interaction:39-39|mutation decreasing interaction:42-42|mutation decreasing interaction:47-47|mutation decreasing interaction:50-50	35s radiolabel:?-?|mutation decreasing interaction:36-36|mutation decreasing interaction:39-39|mutation decreasing interaction:42-42|mutation decreasing interaction:47-47|mutation decreasing interaction:50-50	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20963	uniprotkb:P20963	intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782	intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782	psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym)	psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym)	psi-mi:"MI:0807"(comigration in gel electrophoresis)	Call et al. (2006)	imex:IM-11994|pubmed:17055436	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1166176|imex:IM-11994-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N	refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3 C, 4C|kinetics:The initial rate of tyr17ala dimer formation was 25-fold lower than for the wild-type dimer, although the mutant dimer accumulated to 30% of the wild-type by 60 min.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/15	2014/10/16	rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606	rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606	intact-crc:90F4D9BBF3D16E26|rigid:QWVTfdcrClci4o72YbHfGwcsOTs	false	35s radiolabel:?-?|fusion protein:c-c|mutation decreasing interaction:42-42|mutation decreasing interaction:42-42|mutation decreasing interaction:47-47|mutation decreasing interaction:36-36|mutation decreasing interaction:36-36|mutation decreasing interaction:36-36	35s radiolabel:?-?|fusion protein:c-c|mutation decreasing interaction:42-42|mutation decreasing interaction:42-42|mutation decreasing interaction:47-47|mutation decreasing interaction:36-36|mutation decreasing interaction:36-36|mutation decreasing interaction:36-36	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20963	uniprotkb:P20963	intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782	intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782	psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym)	psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Call et al. (2006)	imex:IM-11994|pubmed:17055436	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1166230|imex:IM-11994-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N	refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3 D, E, 4 D|kinetics:The initial rate of the wild-type asp6ala mixed dimer formation was 8- to 10-fold less than for the wild-type, althought the mixed dimer accumulated to 60% of the wild-type by 60 min.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/15	2014/10/16	rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606	rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606	intact-crc:79EEB2A1EFDA0501|rigid:qkUh2+KHSCaa8otA6CtuT9Y+CrQ	false	mutation decreasing interaction:36-36|mutation decreasing interaction:42-42|mutation decreasing interaction:42-42|mutation decreasing interaction:47-47|35s radiolabel:?-?|fusion protein:c-c	ha tag:c-c|35s radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20963	uniprotkb:P20963	intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782	intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782	psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym)	psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Call et al. (2006)	imex:IM-11994|pubmed:17055436	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1166309|imex:IM-11994-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N	refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4 D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/15	2014/10/16	rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606	rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606	intact-crc:1F14A7245E814FF8|rigid:qkUh2+KHSCaa8otA6CtuT9Y+CrQ	false	fusion protein:c-c|35s radiolabel:?-?|mutation decreasing interaction:42-42	ha tag:c-c|35s radiolabel:?-?|mutation decreasing interaction:47-47	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)