#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Z2S9 uniprotkb:P54319 intact:EBI-2210729|uniprotkb:Q9QX33|uniprotkb:Q9Z2S8|ensembl:ENSRNOP00000014104 intact:EBI-7002453|ensembl:ENSRNOP00000010621|intact:MINT-4299720 psi-mi:flot2_rat(display_long)|uniprotkb:Flot2(gene name)|psi-mi:Flot2(display_short)|uniprotkb:Reg1(gene name synonym)|uniprotkb:Reggie-1(gene name synonym) psi-mi:plap_rat(display_long)|uniprotkb:Plaa(gene name)|psi-mi:Plaa(display_short)|uniprotkb:Plap(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Tivodar et al. (2006) pubmed:17007841|imex:IM-11382|mint:MINT-5219165 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7002482|mint:MINT-3374862|imex:IM-11382-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257729.1|rgd:70993|refseq:NP_114018.1|ensembl:ENSRNOG00000009681(gene)|ensembl:ENSRNOT00000014104(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001931"(uropod)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044860"(protein localization to plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099029"(anchored component of presynaptic active zone membrane)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR031905|interpro:IPR036013|mint:Q9Z2S9|reactome:R-RNO-5213460|reactome:R-RNO-5675482|reactome:R-RNO-8849932|reactome:R-RNO-8980692|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9696264|reactome:R-RNO-9696273|mint:MINT-3374865(identity) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0016005"(phospholipase A2 activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1900045"(negative regulation of protein K63-linked ubiquitination)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013535(PUL)|interpro:IPR015155("PFU (PLAA family ubiquitin binding)")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR038122|mint:P54319|ensembl:ENSRNOG00000007753(gene)|ensembl:ENSRNOT00000010621(transcript)|rgd:621245|refseq:NP_446318.3|mint:MINT-3374863(identity) - comment:"Stoichiometry: 1.0" function:Plays an important role in the regulation of specific inflammatory disease processes|comment:mint figure legend:F2|comment:"The proteins colocalize in DRMs (detergent resistent membrane)."|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2006/10/17 2014/10/16 rogid:jZiEDFJRD3Irrji4NTEpDUzUVeY10116 rogid:UJvHnfZrw6NPhzxndEbAwwzQFMg10116 intact-crc:D644116C35DFAEA9|rigid:o2wdOj5hrlTr5anIW1TXCTwBUWg false - - 1 - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Z2S9 uniprotkb:Q9QUN6 intact:EBI-2210729|uniprotkb:Q9QX33|uniprotkb:Q9Z2S8|ensembl:ENSRNOP00000014104 intact:EBI-7002473|intact:MINT-4299733 psi-mi:flot2_rat(display_long)|uniprotkb:Flot2(gene name)|psi-mi:Flot2(display_short)|uniprotkb:Reg1(gene name synonym)|uniprotkb:Reggie-1(gene name synonym) psi-mi:q9qun6_rat(display_long) psi-mi:"MI:0029"(cosedimentation through density gradient) Tivodar et al. (2006) pubmed:17007841|imex:IM-11382|mint:MINT-5219165 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7002482|mint:MINT-3374862|imex:IM-11382-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257729.1|rgd:70993|refseq:NP_114018.1|ensembl:ENSRNOG00000009681(gene)|ensembl:ENSRNOT00000014104(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001931"(uropod)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044860"(protein localization to plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099029"(anchored component of presynaptic active zone membrane)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR031905|interpro:IPR036013|mint:Q9Z2S9|reactome:R-RNO-5213460|reactome:R-RNO-5675482|reactome:R-RNO-8849932|reactome:R-RNO-8980692|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9696264|reactome:R-RNO-9696273|mint:MINT-3374865(identity) interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|mint:Q9QUN6|mint:MINT-3374864(identity) - comment:"Stoichiometry: 1.0" comment:mint figure legend:F2|comment:"The proteins colocalize in DRMs (detergent resistent membrane)."|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2006/10/17 2014/10/16 rogid:jZiEDFJRD3Irrji4NTEpDUzUVeY10116 rogid:UkhyRrQm7wDBLFGPmztVhzSQFOg10116 intact-crc:D644116C35DFAEA9|rigid:o2wdOj5hrlTr5anIW1TXCTwBUWg false - - 1 - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)