#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P29503 uniprotkb:P18168 intact:EBI-197212|uniprotkb:Q26306|uniprotkb:Q27273|uniprotkb:Q8INP6|uniprotkb:Q8INP7|uniprotkb:Q960M1|ensemblmetazoa:FBpp0081481 intact:EBI-668028|uniprotkb:Q9VB65|intact:EBI-3409750|ensemblmetazoa:FBpp0084498 psi-mi:neur_drome(display_long)|uniprotkb:neur(gene name)|psi-mi:neur(display_short)|uniprotkb:neu(gene name synonym)|uniprotkb:CG11988(orf name) psi-mi:serr_drome(display_long)|uniprotkb:Protein beaded(gene name synonym)|uniprotkb:Ser(gene name)|psi-mi:Ser(display_short)|uniprotkb:Bd(gene name synonym)|uniprotkb:CG6127(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Glittenberg et al. (2006) pubmed:17006545|imex:IM-10946|mint:MINT-5219162 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7001564|mint:MINT-3376020|imex:IM-10946-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163563.1|refseq:NP_476652.1|refseq:NP_731309.1|refseq:NP_731310.1|refseq:NP_731311.1|flybase:FBgn0002932|dip:DIP-17176N|ensemblmetazoa:FBgn0002932(gene)|ensemblmetazoa:FBtr0082003(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0045314"(regulation of compound eye photoreceptor development)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046532"(regulation of photoreceptor cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048749"(compound eye development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR006573(NEUZ)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037962|interpro:IPR043136|mint:P29503|rcsb pdb:2YUE|rcsb pdb:4KG0|mint:MINT-3376021(identity) refseq:NP_524527.3|flybase:FBgn0004197|refseq:NP_001287558.1|ensemblmetazoa:FBgn0004197(gene)|ensemblmetazoa:FBtr0085128(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007423"(sensory organ development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007436"(larval salivary gland morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0030673"(axolemma)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0045179"(apical cortex)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048749"(compound eye development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR026219|mint:P18168|mint:MINT-3376022(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4L|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2006/10/23 2014/10/16 rogid:XvbaN0Fg9K79x+Y56S19ovl/n5U7227 rogid:67XB9KE9JvKFJhBP11iDczeQH1I7227 intact-crc:63F028AF6CE781CA|rigid:0/SNBzEeNQ7T1DjMN8fE+vfa6vs false mutation increasing interaction:701-741(MINT-3376032) mutation decreasing interaction:1353-1353(MINT-3376044)|mutation disrupting interaction:1269-1285(MINT-3376047)|mutation decreasing interaction:1352-1352(MINT-3376041) 1 1 psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot)