#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P61830	uniprotkb:Q06205	intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C	intact:EBI-6956|uniprotkb:D6VZ83|ensemblfungi:YLR449W	psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short)	psi-mi:fkbp4_yeast(display_long)|uniprotkb:FPR4(gene name)|psi-mi:FPR4(display_short)|uniprotkb:YLR449W(locus name)|uniprotkb:L9324.3(orf name)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Histone proline isomerase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Nelson et al. (2006)	imex:IM-12041|pubmed:16959570	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1102534|imex:IM-12041-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G	sgd:S000004441|refseq:NP_013554.3|dip:DIP-909N|mint:Q06205|ensemblfungi:YLR449W(gene)|ensemblfungi:YLR449W_mRNA(transcript)|go:"GO:0000412"(histone peptidyl-prolyl isomerization)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|rcsb pdb:4BF8	go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)	crc64:A6115FEB480AC67A	crc64:CF90C6714F04572E	figure legend:1 A-D|comment:The nucleolin domain of Fpr4 is sufficient to interact with histone H3 and the N-terminal 21 residues of histone H3 are required for Fpr4 interaction.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/29	2014/10/16	rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292	rogid:rDmDSGEgRbtgkLBoJTzmzxxY7B4559292	intact-crc:6990818CE3C48AF9|rigid:x7sPhVoxnpfH0Qin0g7fquP7tA0	false	necessary binding region:2-22	glutathione s tranferase tag:?-?|sufficient binding region:1-280	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06205	uniprotkb:P02309	intact:EBI-6956|uniprotkb:D6VZ83|ensemblfungi:YLR449W	intact:EBI-8113|uniprotkb:D6VQ10|ensemblfungi:YBR009C|ensemblfungi:YNL030W	psi-mi:fkbp4_yeast(display_long)|uniprotkb:FPR4(gene name)|psi-mi:FPR4(display_short)|uniprotkb:YLR449W(locus name)|uniprotkb:L9324.3(orf name)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Histone proline isomerase(gene name synonym)	psi-mi:h4_yeast(display_long)|uniprotkb:N2752(orf name)|uniprotkb:YBR0122(orf name)|uniprotkb:YBR009C(locus name)|uniprotkb:YNL030W(locus name)|uniprotkb:HHF1(gene name)|psi-mi:HHF1(display_short)|uniprotkb:HHF2(gene name)|psi-mi:HHF2(display_short)	psi-mi:"MI:0096"(pull down)	Nelson et al. (2006)	imex:IM-12041|pubmed:16959570	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1102564|imex:IM-12041-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004441|refseq:NP_013554.3|dip:DIP-909N|mint:Q06205|ensemblfungi:YLR449W(gene)|ensemblfungi:YLR449W_mRNA(transcript)|go:"GO:0000412"(histone peptidyl-prolyl isomerization)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|rcsb pdb:4BF8	refseq:NP_009563.1|refseq:NP_014368.1|sgd:S000000213|sgd:S000004975|dip:DIP-418N|mint:P02309|ensemblfungi:YBR009C(gene)|ensemblfungi:YBR009C_mRNA(transcript)|ensemblfungi:YNL030W(gene)|ensemblfungi:YNL030W_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1E6I|rcsb pdb:1ID3|rcsb pdb:1Q1A|rcsb pdb:1SZC|rcsb pdb:1SZD|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2E3K|rcsb pdb:2FSB|rcsb pdb:2H2H|rcsb pdb:2L5A|rcsb pdb:2QQF|rcsb pdb:2QQG|rcsb pdb:3TO6|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:4TWI|rcsb pdb:4TWJ|rcsb pdb:5W0V|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:6RXJ|rcsb pdb:6RXK|rcsb pdb:6RXL|rcsb pdb:6RXM|rcsb pdb:6RXO|rcsb pdb:6RXP|rcsb pdb:6RXQ|rcsb pdb:6RXR|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-4551638|reactome:R-SCE-9018519	go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)	crc64:CF90C6714F04572E	crc64:69B7D1F89E62DE41	figure legend:1 A, C, D|comment:The nucleolin domain of Fpr4 is sufficient to interact with histone H4.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/29	2014/10/16	rogid:rDmDSGEgRbtgkLBoJTzmzxxY7B4559292	rogid:wGtUrumyxGKsW9BEzkBW3FwvwUo559292	intact-crc:30601FC4A82E175A|rigid:n3VooWclUU9xxQj8cMXyCQTWqq4	false	sufficient binding region:1-280|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61830	uniprotkb:Q06205	intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C	intact:EBI-6956|uniprotkb:D6VZ83|ensemblfungi:YLR449W	psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short)	psi-mi:fkbp4_yeast(display_long)|uniprotkb:FPR4(gene name)|psi-mi:FPR4(display_short)|uniprotkb:YLR449W(locus name)|uniprotkb:L9324.3(orf name)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Histone proline isomerase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Nelson et al. (2006)	imex:IM-12041|pubmed:16959570	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1102593|imex:IM-12041-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G	sgd:S000004441|refseq:NP_013554.3|dip:DIP-909N|mint:Q06205|ensemblfungi:YLR449W(gene)|ensemblfungi:YLR449W_mRNA(transcript)|go:"GO:0000412"(histone peptidyl-prolyl isomerization)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|rcsb pdb:4BF8	go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)	crc64:A6115FEB480AC67A	crc64:CF90C6714F04572E	figure legend:1 E, F|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/29	2014/10/16	rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292	rogid:rDmDSGEgRbtgkLBoJTzmzxxY7B4559292	intact-crc:70E2047265F3B8AE|rigid:x7sPhVoxnpfH0Qin0g7fquP7tA0	false	necessary binding region:10-17	glutathione s tranferase tag:?-?|sufficient binding region:1-280	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06205	uniprotkb:P02309	intact:EBI-6956|uniprotkb:D6VZ83|ensemblfungi:YLR449W	intact:EBI-8113|uniprotkb:D6VQ10|ensemblfungi:YBR009C|ensemblfungi:YNL030W	psi-mi:fkbp4_yeast(display_long)|uniprotkb:FPR4(gene name)|psi-mi:FPR4(display_short)|uniprotkb:YLR449W(locus name)|uniprotkb:L9324.3(orf name)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Histone proline isomerase(gene name synonym)	psi-mi:h4_yeast(display_long)|uniprotkb:N2752(orf name)|uniprotkb:YBR0122(orf name)|uniprotkb:YBR009C(locus name)|uniprotkb:YNL030W(locus name)|uniprotkb:HHF1(gene name)|psi-mi:HHF1(display_short)|uniprotkb:HHF2(gene name)|psi-mi:HHF2(display_short)	psi-mi:"MI:0096"(pull down)	Nelson et al. (2006)	imex:IM-12041|pubmed:16959570	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1102609|imex:IM-12041-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004441|refseq:NP_013554.3|dip:DIP-909N|mint:Q06205|ensemblfungi:YLR449W(gene)|ensemblfungi:YLR449W_mRNA(transcript)|go:"GO:0000412"(histone peptidyl-prolyl isomerization)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|rcsb pdb:4BF8	refseq:NP_009563.1|refseq:NP_014368.1|sgd:S000000213|sgd:S000004975|dip:DIP-418N|mint:P02309|ensemblfungi:YBR009C(gene)|ensemblfungi:YBR009C_mRNA(transcript)|ensemblfungi:YNL030W(gene)|ensemblfungi:YNL030W_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1E6I|rcsb pdb:1ID3|rcsb pdb:1Q1A|rcsb pdb:1SZC|rcsb pdb:1SZD|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2E3K|rcsb pdb:2FSB|rcsb pdb:2H2H|rcsb pdb:2L5A|rcsb pdb:2QQF|rcsb pdb:2QQG|rcsb pdb:3TO6|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:4TWI|rcsb pdb:4TWJ|rcsb pdb:5W0V|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:6RXJ|rcsb pdb:6RXK|rcsb pdb:6RXL|rcsb pdb:6RXM|rcsb pdb:6RXO|rcsb pdb:6RXP|rcsb pdb:6RXQ|rcsb pdb:6RXR|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-4551638|reactome:R-SCE-9018519	go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)	crc64:CF90C6714F04572E	crc64:69B7D1F89E62DE41	figure legend:1 E, F|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/29	2014/10/16	rogid:rDmDSGEgRbtgkLBoJTzmzxxY7B4559292	rogid:wGtUrumyxGKsW9BEzkBW3FwvwUo559292	intact-crc:1B50B3183D222530|rigid:n3VooWclUU9xxQj8cMXyCQTWqq4	false	sufficient binding region:1-280|glutathione s tranferase tag:?-?	sufficient binding region:2-14	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61830	uniprotkb:Q06205	intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C	intact:EBI-6956|uniprotkb:D6VZ83|ensemblfungi:YLR449W	psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short)	psi-mi:fkbp4_yeast(display_long)|uniprotkb:FPR4(gene name)|psi-mi:FPR4(display_short)|uniprotkb:YLR449W(locus name)|uniprotkb:L9324.3(orf name)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Histone proline isomerase(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Nelson et al. (2006)	imex:IM-12041|pubmed:16959570	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1102637|imex:IM-12041-5	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G	sgd:S000004441|refseq:NP_013554.3|dip:DIP-909N|mint:Q06205|ensemblfungi:YLR449W(gene)|ensemblfungi:YLR449W_mRNA(transcript)|go:"GO:0000412"(histone peptidyl-prolyl isomerization)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|rcsb pdb:4BF8	go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)	crc64:A6115FEB480AC67A	crc64:CF90C6714F04572E	figure legend:2|comment:The H3 synthetic peptide has a Phe added after Pro30.|resulting-ptm:Fpr4 has cis to trans activity on pro30 of histone H3.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/29	2014/10/16	rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292	rogid:rDmDSGEgRbtgkLBoJTzmzxxY7B4559292	intact-crc:8E12D68C3EE517ED|rigid:x7sPhVoxnpfH0Qin0g7fquP7tA0	false	sufficient binding region:27-31|tag:c-c	glutathione s tranferase tag:?-?|mutation disrupting interaction:323-323	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06205	uniprotkb:P61830	intact:EBI-6956|uniprotkb:D6VZ83|ensemblfungi:YLR449W	intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C	psi-mi:fkbp4_yeast(display_long)|uniprotkb:FPR4(gene name)|psi-mi:FPR4(display_short)|uniprotkb:YLR449W(locus name)|uniprotkb:L9324.3(orf name)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Histone proline isomerase(gene name synonym)	psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short)	psi-mi:"MI:0415"(enzymatic study)	Nelson et al. (2006)	imex:IM-12041|pubmed:16959570	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1102652|imex:IM-12041-6	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004441|refseq:NP_013554.3|dip:DIP-909N|mint:Q06205|ensemblfungi:YLR449W(gene)|ensemblfungi:YLR449W_mRNA(transcript)|go:"GO:0000412"(histone peptidyl-prolyl isomerization)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|rcsb pdb:4BF8	refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G	go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)	crc64:CF90C6714F04572E	crc64:A6115FEB480AC67A	figure legend:2|comment:The H3 synthetic peptide has a Phe added after Pro38.|inhibition:Methylation of K36 in the peptide H3-P38 eliminates the ability of Fpr4 to isomerize this peptide in this assay.|resulting-ptm:Fpr4 has cis to trans activity on pro38 of histone H4.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/29	2014/10/16	rogid:rDmDSGEgRbtgkLBoJTzmzxxY7B4559292	rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292	intact-crc:9DC7EEDFB5D2E334|rigid:x7sPhVoxnpfH0Qin0g7fquP7tA0	false	glutathione s tranferase tag:?-?|mutation disrupting interaction:323-323	sufficient binding region:35-39|tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46995	uniprotkb:P61830	intact:EBI-16985|uniprotkb:D6VW19|ensemblfungi:YJL168C	intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C	psi-mi:set2_yeast(display_long)|uniprotkb:SET2(gene name)|psi-mi:SET2(display_short)|uniprotkb:EZL1(gene name synonym)|uniprotkb:YJL168C(locus name)|uniprotkb:J0520(orf name)|uniprotkb:KMT3(gene name synonym)|uniprotkb:SET domain-containing protein 2(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3(gene name synonym)	psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short)	psi-mi:"MI:0415"(enzymatic study)	Nelson et al. (2006)	imex:IM-12041|pubmed:16959570	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1102676|imex:IM-12041-7	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012367.2|sgd:S000003704|ensemblfungi:YJL168C(gene)|ensemblfungi:YJL168C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006354"(DNA-templated transcription, elongation)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016571"(histone methylation)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030437"(ascospore formation)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0060195"(negative regulation of antisense RNA transcription)|go:"GO:0071441"(negative regulation of histone H3-K14 acetylation)|go:"GO:1900049"(regulation of histone exchange)|go:"GO:2000616"(negative regulation of histone H3-K9 acetylation)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR013257(SRI, Set2 Rpb1 interacting)|interpro:IPR025788|interpro:IPR036020|interpro:IPR038190|interpro:IPR044437|go:"GO:0016575"(histone deacetylation)|rcsb pdb:1E0N|rcsb pdb:2C5Z|dip:DIP-2150N|mint:P46995	refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G	go:"GO:0016571"(histone methylation)	crc64:05436B181E88EFF5	crc64:A6115FEB480AC67A	figure legend:3 A|inhibition:The addition of recombinant Fpr4 slows the rate of methylation by Set2. The Fpr4 isomerase activity causes this inhibition as addition of a catalytically inactive Fpr4 has no influence on the kinetics of methylation.|resulting-ptm:Set2 methylates histone H3.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/29	2014/10/16	rogid:B8N8/ROoqQUdcimRgdGhez6LnDY559292	rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292	intact-crc:CBB2F61337A20626|rigid:wy86Qr0kD7ZjT+nawq0F+1Bm9ac	false	-	sufficient binding region:30-44	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)