#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P62259 uniprotkb:Q8C2B3 intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSMUSP00000070993 intact:EBI-643830|uniprotkb:Q8C2C9|uniprotkb:Q8C8X4|uniprotkb:Q8CB80|uniprotkb:Q8CDA3|uniprotkb:Q9JL72|ensembl:ENSMUSP00000085744 psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short) psi-mi:hdac7_mouse(display_long)|uniprotkb:Histone deacetylase 7A(gene name synonym)|uniprotkb:Hdac7(gene name)|psi-mi:Hdac7(display_short)|uniprotkb:Hdac7a(gene name synonym) psi-mi:"MI:0096"(pull down) Gao et al. (2006) pubmed:16956611|imex:IM-10929|mint:MINT-5219039 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6953408|mint:MINT-3089106|imex:IM-10929-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020849(gene)|ensembl:ENSMUST00000067664(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0006605"(protein targeting)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|refseq:NP_033562.3|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62259|reactome:R-MMU-111447|reactome:R-MMU-2028269|reactome:R-MMU-205025|reactome:R-MMU-2565942|reactome:R-MMU-3371453|reactome:R-MMU-3371511|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-8876198|mint:MINT-3089107(identity) refseq:NP_001191204.1|refseq:NP_001191205.1|refseq:NP_001191206.1|refseq:NP_001191207.1|refseq:NP_062518.2|ensembl:ENSMUSG00000022475|ensembl:ENSMUSG00000022475(gene)|ensembl:ENSMUST00000088402(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0042113"(B cell activation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR033660|interpro:IPR037138|mint:Q8C2B3|reactome:R-MMU-3108214|reactome:R-MMU-350054|go:"GO:0006325"(chromatin organization)|refseq:XP_006521268.1|refseq:XP_006521270.1|refseq:XP_006521271.1|refseq:XP_006521272.1|refseq:XP_006521273.1|dip:DIP-42594N|mint:MINT-3089108(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6B|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/22 2014/10/16 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090 rogid:ndT8bcA7GrstuJrxHqbakZwEg0Q10090 intact-crc:4D67C8B953EB7FC5|rigid:yNhGfv/FMB707WKjMszp84hI1ZA false glutathione s tranferase tag:?-?(MINT-3089112) flag tag:?-?(MINT-3089119)|mutation disrupting interaction:178-178(MINT-3089126)|mutation disrupting interaction:479-479(MINT-3089132)|mutation disrupting interaction:344-344(MINT-3089129) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WU42 uniprotkb:Q8C2B3 intact:EBI-6673326|ensembl:ENSMUSP00000107029|uniprotkb:E9Q9V0|uniprotkb:Q9WU43|uniprotkb:Q9WUC1 intact:EBI-643830|uniprotkb:Q8C2C9|uniprotkb:Q8C8X4|uniprotkb:Q8CB80|uniprotkb:Q8CDA3|uniprotkb:Q9JL72|ensembl:ENSMUSP00000085744 psi-mi:ncor2_mouse(display_long)|uniprotkb:Ncor2(gene name)|psi-mi:Ncor2(display_short)|uniprotkb:Smrt(gene name synonym)|uniprotkb:Silencing mediator of retinoic acid and thyroid hormone receptor(gene name synonym)|uniprotkb:T3 receptor-associating factor(gene name synonym)|uniprotkb:Thyroid-, retinoic-acid-receptor-associated corepressor(gene name synonym) psi-mi:hdac7_mouse(display_long)|uniprotkb:Histone deacetylase 7A(gene name synonym)|uniprotkb:Hdac7(gene name)|psi-mi:Hdac7(display_short)|uniprotkb:Hdac7a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gao et al. (2006) pubmed:16956611|imex:IM-10929|mint:MINT-5219039 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6953485|mint:MINT-3089136|imex:IM-10929-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|mint:Q9WU42|reactome:R-MMU-2173795|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-9029569|reactome:R-MMU-9623433|reactome:R-MMU-9707564|ensembl:ENSMUSG00000029478(gene)|ensembl:ENSMUST00000111398(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021537"(telencephalon development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0030900"(forebrain development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:XP_011239133.1|refseq:NP_001240833.1|refseq:NP_001240834.1|dip:DIP-42595N|mint:MINT-3089137(identity) refseq:NP_001191204.1|refseq:NP_001191205.1|refseq:NP_001191206.1|refseq:NP_001191207.1|refseq:NP_062518.2|ensembl:ENSMUSG00000022475|ensembl:ENSMUSG00000022475(gene)|ensembl:ENSMUST00000088402(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0042113"(B cell activation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR033660|interpro:IPR037138|mint:Q8C2B3|reactome:R-MMU-3108214|reactome:R-MMU-350054|go:"GO:0006325"(chromatin organization)|refseq:XP_006521268.1|refseq:XP_006521270.1|refseq:XP_006521271.1|refseq:XP_006521272.1|refseq:XP_006521273.1|dip:DIP-42594N|mint:MINT-3089144(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/09/22 2014/10/16 rogid:/OTDXDBeSGySNf9Sfg/BDtf8FDA10090 rogid:ndT8bcA7GrstuJrxHqbakZwEg0Q10090 intact-crc:BEE54D3B87299ADF|rigid:zNxOYMWuhemxAqwu9uaUatKIw+o false binding-associated region:1188-1833(MINT-3089255) flag tag:?-?(MINT-3089145) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8C2B3 uniprotkb:Q60929 intact:EBI-643830|uniprotkb:Q8C2C9|uniprotkb:Q8C8X4|uniprotkb:Q8CB80|uniprotkb:Q8CDA3|uniprotkb:Q9JL72|ensembl:ENSMUSP00000085744 intact:EBI-2639094|uniprotkb:Q3V155|uniprotkb:Q4VA09|uniprotkb:Q6P8Q3|ensembl:ENSMUSP00000117496|ensembl:ENSMUSP00000138566 psi-mi:hdac7_mouse(display_long)|uniprotkb:Histone deacetylase 7A(gene name synonym)|uniprotkb:Hdac7(gene name)|psi-mi:Hdac7(display_short)|uniprotkb:Hdac7a(gene name synonym) psi-mi:mef2a_mouse(display_long)|uniprotkb:Mef2a(gene name)|psi-mi:Mef2a(display_short) psi-mi:"MI:0018"(two hybrid) Gao et al. (2006) pubmed:16956611|imex:IM-10929|mint:MINT-5219039 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6953590|mint:MINT-3089169|imex:IM-10929-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191204.1|refseq:NP_001191205.1|refseq:NP_001191206.1|refseq:NP_001191207.1|refseq:NP_062518.2|ensembl:ENSMUSG00000022475|ensembl:ENSMUSG00000022475(gene)|ensembl:ENSMUST00000088402(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0042113"(B cell activation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR033660|interpro:IPR037138|mint:Q8C2B3|reactome:R-MMU-3108214|reactome:R-MMU-350054|go:"GO:0006325"(chromatin organization)|refseq:XP_006521268.1|refseq:XP_006521270.1|refseq:XP_006521271.1|refseq:XP_006521272.1|refseq:XP_006521273.1|dip:DIP-42594N|mint:MINT-3089178(identity) refseq:NP_001278120.1|refseq:NP_001278121.1|refseq:NP_001278124.1|refseq:NP_001278125.1|refseq:XP_011249116.1|refseq:XP_017177500.1|refseq:NP_001028885.1|refseq:XP_006540749.1|ensembl:ENSMUSG00000030557(gene)|ensembl:ENSMUST00000135493(transcript)|ensembl:ENSMUST00000156690(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007507"(heart development)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0055005"(ventricular cardiac myofibril assembly)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070375"(ERK5 cascade)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR022102|interpro:IPR033896|interpro:IPR036879|mint:Q60929|mint:MINT-3089170(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/09/22 2014/10/16 rogid:ndT8bcA7GrstuJrxHqbakZwEg0Q10090 rogid:Z/iMKtSs4pNMyjZ2o808rHfEuGk10090 intact-crc:298DF7B21799DFD7|rigid:KxyK3ofFKNwQpoV3sLMsYgtyuKk false mutation decreasing interaction:178-178(MINT-3089201)|mutation decreasing interaction:344-344(MINT-3089204)|tag:?-?(MINT-3089179)|binding-associated region:2-533(MINT-3089190)|mutation decreasing interaction:479-479(MINT-3089207) tag:?-?(MINT-3089172) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8C2B3 uniprotkb:P62259 intact:EBI-643830|uniprotkb:Q8C2C9|uniprotkb:Q8C8X4|uniprotkb:Q8CB80|uniprotkb:Q8CDA3|uniprotkb:Q9JL72|ensembl:ENSMUSP00000085744 intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSMUSP00000070993 psi-mi:hdac7_mouse(display_long)|uniprotkb:Histone deacetylase 7A(gene name synonym)|uniprotkb:Hdac7(gene name)|psi-mi:Hdac7(display_short)|uniprotkb:Hdac7a(gene name synonym) psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short) psi-mi:"MI:0018"(two hybrid) Gao et al. (2006) pubmed:16956611|imex:IM-10929|mint:MINT-5219039 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6953668|mint:MINT-3089216|imex:IM-10929-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191204.1|refseq:NP_001191205.1|refseq:NP_001191206.1|refseq:NP_001191207.1|refseq:NP_062518.2|ensembl:ENSMUSG00000022475|ensembl:ENSMUSG00000022475(gene)|ensembl:ENSMUST00000088402(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0042113"(B cell activation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR033660|interpro:IPR037138|mint:Q8C2B3|reactome:R-MMU-3108214|reactome:R-MMU-350054|go:"GO:0006325"(chromatin organization)|refseq:XP_006521268.1|refseq:XP_006521270.1|refseq:XP_006521271.1|refseq:XP_006521272.1|refseq:XP_006521273.1|dip:DIP-42594N|mint:MINT-3089225(identity) ensembl:ENSMUSG00000020849(gene)|ensembl:ENSMUST00000067664(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0006605"(protein targeting)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|refseq:NP_033562.3|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62259|reactome:R-MMU-111447|reactome:R-MMU-2028269|reactome:R-MMU-205025|reactome:R-MMU-2565942|reactome:R-MMU-3371453|reactome:R-MMU-3371511|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-8876198|mint:MINT-3089217(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6D|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/09/22 2014/10/16 rogid:ndT8bcA7GrstuJrxHqbakZwEg0Q10090 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090 intact-crc:27D03AE86898D81A|rigid:yNhGfv/FMB707WKjMszp84hI1ZA false mutation disrupting interaction:178-178(MINT-3089235)|binding-associated region:2-533(MINT-3089233)|tag:?-?(MINT-3089229)|mutation disrupting interaction:344-344(MINT-3089238)|mutation disrupting interaction:479-479(MINT-3089241) tag:?-?(MINT-3089221) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)