#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P90629	uniprotkb:Q952G2	intact:EBI-1006888|ensemblprotists:EAN79148	intact:EBI-1006915|ensemblprotists:EAN80273	psi-mi:p90629_9tryp(display_long)|uniprotkb:gBP21(gene name)|psi-mi:gBP21(display_short)	psi-mi:q952g2_9tryp(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Schumacher et al. (2006)	imex:IM-11859|pubmed:16923390	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1006893|imex:IM-11859-1|rcsb pdb:2GIA	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR032680|ensemblprotists:EAN79148(transcript)|ensemblprotists:Tb11.55.0009(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016556"(mRNA modification)|go:"GO:0031981"(nuclear lumen)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	interpro:IPR032680|ensemblprotists:EAN80273(transcript)|ensemblprotists:Tb11.01.4860(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009451"(RNA modification)|go:"GO:0020023"(kinetoplast)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	-	-	-	comment:"The sequence of the protein MRP1 used here has a Glu instead of a Leu at position 43, unlike the Uniprot sequence (P90629)."|figure legend:1, Table 1|comment:The MRP1 sequence used had the N-terminal mito-targeting sequence and a C-terminal region found to cause insolubility removed.|comment:The MRP2 sequence used had the N-terminal mito-targeting sequence removed.|comment:The model includes 8 acetate molecules and 572 water molecules.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/07	2014/10/16	rogid:mmw/eWdZENBvdbib8wob1vuL3W45691	rogid:GHl2M8BZvk6pn/FaGjotg0oFId45691	intact-crc:C5EBDAF94D58757B|rigid:Sm5Ke02nu5/DtoXk+lL41sHTx9U	false	sufficient binding region:28-176|L-selenomethionine:46-46|L-selenomethionine:109-109|L-selenomethionine:139-139	sufficient binding region:56-175,188-221|L-selenomethionine:110-110|L-selenomethionine:125-125|L-selenomethionine:204-204	2	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P90629	uniprotkb:Q952G2	intact:EBI-1006888|ensemblprotists:EAN79148	intact:EBI-1006915|ensemblprotists:EAN80273	psi-mi:p90629_9tryp(display_long)|uniprotkb:gBP21(gene name)|psi-mi:gBP21(display_short)	psi-mi:q952g2_9tryp(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Schumacher et al. (2006)	imex:IM-11859|pubmed:16923390	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1006893|imex:IM-11859-1|rcsb pdb:2GIA	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR032680|ensemblprotists:EAN79148(transcript)|ensemblprotists:Tb11.55.0009(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016556"(mRNA modification)|go:"GO:0031981"(nuclear lumen)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	interpro:IPR032680|ensemblprotists:EAN80273(transcript)|ensemblprotists:Tb11.01.4860(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009451"(RNA modification)|go:"GO:0020023"(kinetoplast)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	-	-	-	comment:"The sequence of the protein MRP1 used here has a Glu instead of a Leu at position 43, unlike the Uniprot sequence (P90629)."|figure legend:1, Table 1|comment:The MRP1 sequence used had the N-terminal mito-targeting sequence and a C-terminal region found to cause insolubility removed.|comment:The MRP2 sequence used had the N-terminal mito-targeting sequence removed.|comment:The model includes 8 acetate molecules and 572 water molecules.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/07	2014/10/16	rogid:mmw/eWdZENBvdbib8wob1vuL3W45691	rogid:GHl2M8BZvk6pn/FaGjotg0oFId45691	intact-crc:C5EBDAF94D58757B|rigid:Sm5Ke02nu5/DtoXk+lL41sHTx9U	false	sufficient binding region:28-176|L-selenomethionine:46-46|L-selenomethionine:109-109|L-selenomethionine:139-139	sufficient binding region:55-175,188-221|L-selenomethionine:110-110|L-selenomethionine:125-125|L-selenomethionine:204-204	2	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P90629	uniprotkb:Q952G2	intact:EBI-1006888|ensemblprotists:EAN79148	intact:EBI-1006915|ensemblprotists:EAN80273	psi-mi:p90629_9tryp(display_long)|uniprotkb:gBP21(gene name)|psi-mi:gBP21(display_short)	psi-mi:q952g2_9tryp(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Schumacher et al. (2006)	imex:IM-11859|pubmed:16923390	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1008007|imex:IM-11859-2|rcsb pdb:2GID	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR032680|ensemblprotists:EAN79148(transcript)|ensemblprotists:Tb11.55.0009(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016556"(mRNA modification)|go:"GO:0031981"(nuclear lumen)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	interpro:IPR032680|ensemblprotists:EAN80273(transcript)|ensemblprotists:Tb11.01.4860(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009451"(RNA modification)|go:"GO:0020023"(kinetoplast)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	-	-	-	comment:"The sequence of the protein MRP1 used here has a Glu instead of a Leu at position 43, unlike the Uniprot sequence (P90629)."|figure legend:1, Table 1|comment:The MRP1 sequence used had the N-terminal mito-targeting sequence and a C-terminal region found to cause insolubility removed.|comment:The MRP2 sequence used had the N-terminal mito-targeting sequence removed.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/07	2014/10/16	rogid:mmw/eWdZENBvdbib8wob1vuL3W45691	rogid:GHl2M8BZvk6pn/FaGjotg0oFId45691	intact-crc:019AB9321E496BB1|rigid:Sm5Ke02nu5/DtoXk+lL41sHTx9U	false	L-selenomethionine:46-46|L-selenomethionine:109-109|L-selenomethionine:139-139|sufficient binding region:28-176	sufficient binding region:59-175,188-221|L-selenomethionine:110-110|L-selenomethionine:125-125|L-selenomethionine:204-204	2	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P90629	uniprotkb:Q952G2	intact:EBI-1006888|ensemblprotists:EAN79148	intact:EBI-1006915|ensemblprotists:EAN80273	psi-mi:p90629_9tryp(display_long)|uniprotkb:gBP21(gene name)|psi-mi:gBP21(display_short)	psi-mi:q952g2_9tryp(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Schumacher et al. (2006)	imex:IM-11859|pubmed:16923390	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1008007|imex:IM-11859-2|rcsb pdb:2GID	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR032680|ensemblprotists:EAN79148(transcript)|ensemblprotists:Tb11.55.0009(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016556"(mRNA modification)|go:"GO:0031981"(nuclear lumen)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	interpro:IPR032680|ensemblprotists:EAN80273(transcript)|ensemblprotists:Tb11.01.4860(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009451"(RNA modification)|go:"GO:0020023"(kinetoplast)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	-	-	-	comment:"The sequence of the protein MRP1 used here has a Glu instead of a Leu at position 43, unlike the Uniprot sequence (P90629)."|figure legend:1, Table 1|comment:The MRP1 sequence used had the N-terminal mito-targeting sequence and a C-terminal region found to cause insolubility removed.|comment:The MRP2 sequence used had the N-terminal mito-targeting sequence removed.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/07	2014/10/16	rogid:mmw/eWdZENBvdbib8wob1vuL3W45691	rogid:GHl2M8BZvk6pn/FaGjotg0oFId45691	intact-crc:019AB9321E496BB1|rigid:Sm5Ke02nu5/DtoXk+lL41sHTx9U	false	L-selenomethionine:46-46|L-selenomethionine:109-109|L-selenomethionine:139-139|sufficient binding region:28-176	sufficient binding region:60-175,188-221|L-selenomethionine:110-110|L-selenomethionine:125-125|L-selenomethionine:204-204	2	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-1008097	uniprotkb:P90629	-	intact:EBI-1006888|ensemblprotists:EAN79148	psi-mi:gnd7-506_trybr_grna(display_short)|psi-mi:EBI-1008097(display_long)	psi-mi:p90629_9tryp(display_long)|uniprotkb:gBP21(gene name)|psi-mi:gBP21(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Schumacher et al. (2006)	imex:IM-11859|pubmed:16923390	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1008104|rcsb pdb:2GJE|imex:IM-11859-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	ddbj/embl/genbank:M15322(see-also)	interpro:IPR032680|ensemblprotists:EAN79148(transcript)|ensemblprotists:Tb11.55.0009(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016556"(mRNA modification)|go:"GO:0031981"(nuclear lumen)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	-	-	-	comment:"The sequence of the protein MRP1 used here has a Glu instead of a Leu at position 43, unlike the Uniprot sequence (P90629)."|comment:The MRP1 sequence used had the N-terminal mito-targeting sequence and a C-terminal region found to cause insolubility removed.|comment:The MRP2 sequence used had the N-terminal mito-targeting sequence removed.|comment:The heterotetramer, identical to that in the apo structures, was generated by crystallographic symmetry.|figure legend:5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/07	2014/10/16	crc64:06D78883CD82EBC7	rogid:mmw/eWdZENBvdbib8wob1vuL3W45691	intact-crc:54206F0E89F710A8	false	sufficient binding region:11-23,31-35	L-selenomethionine:46-46|L-selenomethionine:109-109|L-selenomethionine:139-139|sufficient binding region:28-173	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-1008097	uniprotkb:Q952G2	-	intact:EBI-1006915|ensemblprotists:EAN80273	psi-mi:gnd7-506_trybr_grna(display_short)|psi-mi:EBI-1008097(display_long)	psi-mi:q952g2_9tryp(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Schumacher et al. (2006)	imex:IM-11859|pubmed:16923390	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1008104|rcsb pdb:2GJE|imex:IM-11859-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	ddbj/embl/genbank:M15322(see-also)	interpro:IPR032680|ensemblprotists:EAN80273(transcript)|ensemblprotists:Tb11.01.4860(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009451"(RNA modification)|go:"GO:0020023"(kinetoplast)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	-	-	-	comment:"The sequence of the protein MRP1 used here has a Glu instead of a Leu at position 43, unlike the Uniprot sequence (P90629)."|comment:The MRP1 sequence used had the N-terminal mito-targeting sequence and a C-terminal region found to cause insolubility removed.|comment:The MRP2 sequence used had the N-terminal mito-targeting sequence removed.|comment:The heterotetramer, identical to that in the apo structures, was generated by crystallographic symmetry.|figure legend:5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/07	2014/10/16	crc64:06D78883CD82EBC7	rogid:GHl2M8BZvk6pn/FaGjotg0oFId45691	intact-crc:54206F0E89F710A8	false	sufficient binding region:11-23,31-35	sufficient binding region:66-175,188-221|L-selenomethionine:110-110|L-selenomethionine:125-125|L-selenomethionine:204-204	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-1008097	uniprotkb:P90629	-	intact:EBI-1006888|ensemblprotists:EAN79148	psi-mi:gnd7-506_trybr_grna(display_short)|psi-mi:EBI-1008097(display_long)	psi-mi:p90629_9tryp(display_long)|uniprotkb:gBP21(gene name)|psi-mi:gBP21(display_short)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Schumacher et al. (2006)	imex:IM-11859|pubmed:16923390	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1008171|imex:IM-11859-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	ddbj/embl/genbank:M15322(see-also)	interpro:IPR032680|ensemblprotists:EAN79148(transcript)|ensemblprotists:Tb11.55.0009(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016556"(mRNA modification)|go:"GO:0031981"(nuclear lumen)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	rcsb pdb:2GJE(see-also)	-	-	comment:"The sequence of the protein MRP1 used here has a Glu instead of a Leu at position 43, unlike the Uniprot sequence (P90629)."|comment:The MRP1 sequence used had the N-terminal mito-targeting sequence and a C-terminal region found to cause insolubility removed.|comment:The MRP2 sequence used had the N-terminal mito-targeting sequence removed.|comment:"Only weak binding was observed to the  oligo(U)-tail (Kd approx. 150 nM) and essentially no binding  to stem/loop I alone, except when these molecules were heated to unfold them."|figure legend:3 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/07	2014/10/16	crc64:06D78883CD82EBC7	rogid:mmw/eWdZENBvdbib8wob1vuL3W45691	intact-crc:94F16FD2C91163A6	false	sufficient binding region:19-44|tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-1008097	uniprotkb:Q952G2	-	intact:EBI-1006915|ensemblprotists:EAN80273	psi-mi:gnd7-506_trybr_grna(display_short)|psi-mi:EBI-1008097(display_long)	psi-mi:q952g2_9tryp(display_long)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Schumacher et al. (2006)	imex:IM-11859|pubmed:16923390	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1008171|imex:IM-11859-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	ddbj/embl/genbank:M15322(see-also)	interpro:IPR032680|ensemblprotists:EAN80273(transcript)|ensemblprotists:Tb11.01.4860(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009451"(RNA modification)|go:"GO:0020023"(kinetoplast)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	rcsb pdb:2GJE(see-also)	-	-	comment:"The sequence of the protein MRP1 used here has a Glu instead of a Leu at position 43, unlike the Uniprot sequence (P90629)."|comment:The MRP1 sequence used had the N-terminal mito-targeting sequence and a C-terminal region found to cause insolubility removed.|comment:The MRP2 sequence used had the N-terminal mito-targeting sequence removed.|comment:"Only weak binding was observed to the  oligo(U)-tail (Kd approx. 150 nM) and essentially no binding  to stem/loop I alone, except when these molecules were heated to unfold them."|figure legend:3 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/07	2014/10/16	crc64:06D78883CD82EBC7	rogid:GHl2M8BZvk6pn/FaGjotg0oFId45691	intact-crc:94F16FD2C91163A6	false	sufficient binding region:19-44|tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-1008097	uniprotkb:P90629	-	intact:EBI-1006888|ensemblprotists:EAN79148	psi-mi:gnd7-506_trybr_grna(display_short)|psi-mi:EBI-1008097(display_long)	psi-mi:p90629_9tryp(display_long)|uniprotkb:gBP21(gene name)|psi-mi:gBP21(display_short)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Schumacher et al. (2006)	imex:IM-11859|pubmed:16923390	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1008201|imex:IM-11859-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	ddbj/embl/genbank:M15322(see-also)	interpro:IPR032680|ensemblprotists:EAN79148(transcript)|ensemblprotists:Tb11.55.0009(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016556"(mRNA modification)|go:"GO:0031981"(nuclear lumen)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	rcsb pdb:2GJE(see-also)	-	-	comment:"The sequence of the protein MRP1 used here has a Glu instead of a Leu at position 43, unlike the Uniprot sequence (P90629)."|comment:The MRP1 sequence used had the N-terminal mito-targeting sequence and a C-terminal region found to cause insolubility removed.|comment:The MRP2 sequence used had the N-terminal mito-targeting sequence removed.|comment:"Only weak binding was observed to the  oligo(U)-tail (Kd approx. 150 nM) and essentially no binding  to stem/loop I alone, except when these molecules were heated to unfold them."|comment:The oligonucleotide was 5'-fluorescinated.|inhibition:"Increasing the salt concentration decreased the binding and at concentrations of NaCl above 0.2 M binding is quickly abrogated. (Kds - 5.1 E-9 at 0.05 M NaCl, 8.5 E-9 M at 0.1 M NaCl, 2.7 E-8 M in 0.15 M NaCl, 2.06 E-8 in 0.2 M NaCl and no saturable binding at 0.3 and 0.4 M NaCl.)"|figure legend:3 B, C, S1|comment:"Magnesium is not required for high affinity binding (Kd 6.9 E-9 in the presence of 5.0 E-3 M magnesium ions versus 5.1 E-3 M in its absence)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/07	2014/10/16	crc64:06D78883CD82EBC7	rogid:mmw/eWdZENBvdbib8wob1vuL3W45691	intact-crc:43A79F48D57BFA5D	false	sufficient binding region:4-44|tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-1008097	uniprotkb:Q952G2	-	intact:EBI-1006915|ensemblprotists:EAN80273	psi-mi:gnd7-506_trybr_grna(display_short)|psi-mi:EBI-1008097(display_long)	psi-mi:q952g2_9tryp(display_long)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Schumacher et al. (2006)	imex:IM-11859|pubmed:16923390	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1008201|imex:IM-11859-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	ddbj/embl/genbank:M15322(see-also)	interpro:IPR032680|ensemblprotists:EAN80273(transcript)|ensemblprotists:Tb11.01.4860(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009451"(RNA modification)|go:"GO:0020023"(kinetoplast)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	rcsb pdb:2GJE(see-also)	-	-	comment:"The sequence of the protein MRP1 used here has a Glu instead of a Leu at position 43, unlike the Uniprot sequence (P90629)."|comment:The MRP1 sequence used had the N-terminal mito-targeting sequence and a C-terminal region found to cause insolubility removed.|comment:The MRP2 sequence used had the N-terminal mito-targeting sequence removed.|comment:"Only weak binding was observed to the  oligo(U)-tail (Kd approx. 150 nM) and essentially no binding  to stem/loop I alone, except when these molecules were heated to unfold them."|comment:The oligonucleotide was 5'-fluorescinated.|inhibition:"Increasing the salt concentration decreased the binding and at concentrations of NaCl above 0.2 M binding is quickly abrogated. (Kds - 5.1 E-9 at 0.05 M NaCl, 8.5 E-9 M at 0.1 M NaCl, 2.7 E-8 M in 0.15 M NaCl, 2.06 E-8 in 0.2 M NaCl and no saturable binding at 0.3 and 0.4 M NaCl.)"|figure legend:3 B, C, S1|comment:"Magnesium is not required for high affinity binding (Kd 6.9 E-9 in the presence of 5.0 E-3 M magnesium ions versus 5.1 E-3 M in its absence)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/07	2014/10/16	crc64:06D78883CD82EBC7	rogid:GHl2M8BZvk6pn/FaGjotg0oFId45691	intact-crc:43A79F48D57BFA5D	false	sufficient binding region:4-44|tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-1008097	uniprotkb:P90629	-	intact:EBI-1006888|ensemblprotists:EAN79148	psi-mi:gnd7-506_trybr_grna(display_short)|psi-mi:EBI-1008097(display_long)	psi-mi:p90629_9tryp(display_long)|uniprotkb:gBP21(gene name)|psi-mi:gBP21(display_short)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Schumacher et al. (2006)	imex:IM-11859|pubmed:16923390	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1008228|imex:IM-11859-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	ddbj/embl/genbank:M15322(see-also)	interpro:IPR032680|ensemblprotists:EAN79148(transcript)|ensemblprotists:Tb11.55.0009(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016556"(mRNA modification)|go:"GO:0031981"(nuclear lumen)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	rcsb pdb:2GJE(see-also)	-	-	comment:"The sequence of the protein MRP1 used here has a Glu instead of a Leu at position 43, unlike the Uniprot sequence (P90629)."|comment:The MRP1 sequence used had the N-terminal mito-targeting sequence and a C-terminal region found to cause insolubility removed.|comment:The MRP2 sequence used had the N-terminal mito-targeting sequence removed.|comment:The oligonucleotide was 5'-fluorescinated.|figure legend:S3 B|comment:The RNA molecule was heated to 100 degrees C to unfold it.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/07	2014/10/16	crc64:06D78883CD82EBC7	rogid:mmw/eWdZENBvdbib8wob1vuL3W45691	intact-crc:AA50A470EA86CB21	false	sufficient binding region:4-12|tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-1008097	uniprotkb:Q952G2	-	intact:EBI-1006915|ensemblprotists:EAN80273	psi-mi:gnd7-506_trybr_grna(display_short)|psi-mi:EBI-1008097(display_long)	psi-mi:q952g2_9tryp(display_long)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Schumacher et al. (2006)	imex:IM-11859|pubmed:16923390	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	taxid:5691(9tryp)|taxid:5691(Trypanosoma brucei)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1008228|imex:IM-11859-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	ddbj/embl/genbank:M15322(see-also)	interpro:IPR032680|ensemblprotists:EAN80273(transcript)|ensemblprotists:Tb11.01.4860(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009451"(RNA modification)|go:"GO:0020023"(kinetoplast)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|rcsb pdb:2GIA|rcsb pdb:2GID|rcsb pdb:2GJE	rcsb pdb:2GJE(see-also)	-	-	comment:"The sequence of the protein MRP1 used here has a Glu instead of a Leu at position 43, unlike the Uniprot sequence (P90629)."|comment:The MRP1 sequence used had the N-terminal mito-targeting sequence and a C-terminal region found to cause insolubility removed.|comment:The MRP2 sequence used had the N-terminal mito-targeting sequence removed.|comment:The oligonucleotide was 5'-fluorescinated.|figure legend:S3 B|comment:The RNA molecule was heated to 100 degrees C to unfold it.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/07	2014/10/16	crc64:06D78883CD82EBC7	rogid:GHl2M8BZvk6pn/FaGjotg0oFId45691	intact-crc:AA50A470EA86CB21	false	sufficient binding region:4-12|tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)