#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P08539	uniprotkb:P22219	intact:EBI-7376|uniprotkb:D3DKU8|ensemblfungi:YHR005C	intact:EBI-20347|uniprotkb:D6VQ98|ensemblfungi:YBR097W	psi-mi:gpa1_yeast(display_long)|uniprotkb:YHR005C(locus name)|uniprotkb:GPA1(gene name)|psi-mi:GPA1(display_short)|uniprotkb:CDC70(gene name synonym)|uniprotkb:DAC1(gene name synonym)|uniprotkb:SCG1(gene name synonym)|uniprotkb:GP1-alpha(gene name synonym)	psi-mi:vps15_yeast(display_long)|uniprotkb:VPS15(gene name)|psi-mi:VPS15(display_short)|uniprotkb:GRD8(gene name synonym)|uniprotkb:VPL19(gene name synonym)|uniprotkb:YBR0825(orf name)|uniprotkb:YBR097W(locus name)|uniprotkb:VAC4(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 15(gene name synonym)|uniprotkb:Golgi-retention defective mutant protein 8(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Slessareva et al. (2006)	imex:IM-11946|pubmed:16839886	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-973716|imex:IM-11946-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011868.1|sgd:S000001047|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-416482|dip:DIP-15N|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|ensemblfungi:YHR005C(gene)|ensemblfungi:YHR005C_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071701"(regulation of MAPK export from nucleus)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:1SCG|rcsb pdb:7AD3	refseq:NP_009655.2|sgd:S000000301|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071561"(nucleus-vacuole junction)|ensemblfungi:YBR097W(gene)|go:"GO:0106310"(protein serine kinase activity)|ensemblfungi:YBR097W_mRNA(transcript)|go:"GO:0106311"|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|rcsb pdb:3GRE|rcsb pdb:5DFZ|rcsb pdb:5KC2|reactome:R-SCE-1632852|reactome:R-SCE-1660514|reactome:R-SCE-1660516|reactome:R-SCE-1660517|reactome:R-SCE-5668599|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|dip:DIP-814N|mint:P22219	psi-mi:"MI:0469"(intact)	crc64:2E87C546E133D6E5	crc64:247EBA5531E41FFB	figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/19	2014/10/16	rogid:SxuqaRpicb7ZBsQju2vD6C8h3X4559292	rogid:bDKA6IlevNTmtSQqleAbkY7/eAI559292	intact-crc:6075781D3F246C4A|rigid:tWAdwaeCRy/IxzICw2Uyg1j0TB4	false	mutation decreasing interaction:323-323	calmodulin binding peptide plus protein a tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P08539	uniprotkb:P22543	intact:EBI-7376|uniprotkb:D3DKU8|ensemblfungi:YHR005C	intact:EBI-20405|uniprotkb:D6VYN8|ensemblfungi:YLR240W	psi-mi:gpa1_yeast(display_long)|uniprotkb:YHR005C(locus name)|uniprotkb:GPA1(gene name)|psi-mi:GPA1(display_short)|uniprotkb:CDC70(gene name synonym)|uniprotkb:DAC1(gene name synonym)|uniprotkb:SCG1(gene name synonym)|uniprotkb:GP1-alpha(gene name synonym)	psi-mi:vps34_yeast(display_long)|uniprotkb:VPS34(gene name)|psi-mi:VPS34(display_short)|uniprotkb:END12(gene name synonym)|uniprotkb:PEP15(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 34(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 29(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 15(gene name synonym)|uniprotkb:VPL7(gene name synonym)|uniprotkb:VPT29(gene name synonym)|uniprotkb:L9672.10(orf name)|uniprotkb:YLR240W(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Slessareva et al. (2006)	imex:IM-11946|pubmed:16839886	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-973747|imex:IM-11946-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011868.1|sgd:S000001047|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-416482|dip:DIP-15N|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|ensemblfungi:YHR005C(gene)|ensemblfungi:YHR005C_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071701"(regulation of MAPK export from nucleus)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:1SCG|rcsb pdb:7AD3	refseq:NP_013341.1|sgd:S000004230|ensemblfungi:YLR240W(gene)|ensemblfungi:YLR240W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:2001159"(regulation of protein localization by the Cvt pathway)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|rcsb pdb:5DFZ|rcsb pdb:5KC2|reactome:R-SCE-1632852|reactome:R-SCE-1660514|reactome:R-SCE-1660516|reactome:R-SCE-1660517|reactome:R-SCE-5668599|dip:DIP-97N|mint:P22543	psi-mi:"MI:0469"(intact)	crc64:2E87C546E133D6E5	crc64:806E3404EF260287	figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/19	2014/10/16	rogid:SxuqaRpicb7ZBsQju2vD6C8h3X4559292	rogid:a8TnZYg+pKpfjIhB9uInf8Y0uOw559292	intact-crc:4811FEEA169B60F8|rigid:Zkd9V1H/z5/F/R6EekAyMKBdRqU	false	-	calmodulin binding peptide plus protein a tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P08539	uniprotkb:P18851	intact:EBI-7376|uniprotkb:D3DKU8|ensemblfungi:YHR005C	intact:EBI-7390|uniprotkb:D6W2R8|ensemblfungi:YOR212W	psi-mi:gpa1_yeast(display_long)|uniprotkb:YHR005C(locus name)|uniprotkb:GPA1(gene name)|psi-mi:GPA1(display_short)|uniprotkb:CDC70(gene name synonym)|uniprotkb:DAC1(gene name synonym)|uniprotkb:SCG1(gene name synonym)|uniprotkb:GP1-alpha(gene name synonym)	psi-mi:gbb_yeast(display_long)|uniprotkb:YOR50-2(orf name)|uniprotkb:YOR212W(locus name)|uniprotkb:STE4(gene name)|psi-mi:STE4(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Slessareva et al. (2006)	imex:IM-11946|pubmed:16839886	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-973784|imex:IM-11946-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011868.1|sgd:S000001047|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-416482|dip:DIP-15N|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|ensemblfungi:YHR005C(gene)|ensemblfungi:YHR005C_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071701"(regulation of MAPK export from nucleus)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:1SCG|rcsb pdb:7AD3	sgd:S000005738|refseq:NP_014855.3|mint:P18851|dip:DIP-954N|ensemblfungi:YOR212W(gene)|ensemblfungi:YOR212W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005937"(mating projection)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0043577"(chemotropism)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|go:"GO:1903260"(protein localization to mating projection tip)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1SCG|reactome:R-SCE-6814122	psi-mi:"MI:0469"(intact)	crc64:2E87C546E133D6E5	crc64:4B0E26040AAA83E5	figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/19	2014/10/16	rogid:SxuqaRpicb7ZBsQju2vD6C8h3X4559292	rogid:nDgadSWQPcmSvQlIEjpNHPl3Hjc559292	intact-crc:E356DB3AE7F3B636|rigid:qZT9XuLaPi6PXvNRlzA0mIUc71A	false	-	calmodulin binding peptide plus protein a tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P18851	uniprotkb:P08539	intact:EBI-7390|uniprotkb:D6W2R8|ensemblfungi:YOR212W	intact:EBI-7376|uniprotkb:D3DKU8|ensemblfungi:YHR005C	psi-mi:gbb_yeast(display_long)|uniprotkb:YOR50-2(orf name)|uniprotkb:YOR212W(locus name)|uniprotkb:STE4(gene name)|psi-mi:STE4(display_short)	psi-mi:gpa1_yeast(display_long)|uniprotkb:YHR005C(locus name)|uniprotkb:GPA1(gene name)|psi-mi:GPA1(display_short)|uniprotkb:CDC70(gene name synonym)|uniprotkb:DAC1(gene name synonym)|uniprotkb:SCG1(gene name synonym)|uniprotkb:GP1-alpha(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Slessareva et al. (2006)	imex:IM-11946|pubmed:16839886	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-973875|imex:IM-11946-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005738|refseq:NP_014855.3|mint:P18851|dip:DIP-954N|ensemblfungi:YOR212W(gene)|ensemblfungi:YOR212W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005937"(mating projection)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0043577"(chemotropism)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|go:"GO:1903260"(protein localization to mating projection tip)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1SCG|reactome:R-SCE-6814122	refseq:NP_011868.1|sgd:S000001047|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-416482|dip:DIP-15N|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|ensemblfungi:YHR005C(gene)|ensemblfungi:YHR005C_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071701"(regulation of MAPK export from nucleus)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:1SCG|rcsb pdb:7AD3	psi-mi:"MI:0469"(intact)	crc64:4B0E26040AAA83E5	crc64:2E87C546E133D6E5	figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/19	2014/10/16	rogid:nDgadSWQPcmSvQlIEjpNHPl3Hjc559292	rogid:SxuqaRpicb7ZBsQju2vD6C8h3X4559292	intact-crc:9DF62E8C337B953D|rigid:qZT9XuLaPi6PXvNRlzA0mIUc71A	false	flag tag:?-?	calmodulin binding peptide plus protein a tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P18851	uniprotkb:P18851	intact:EBI-7390|uniprotkb:D6W2R8|ensemblfungi:YOR212W	intact:EBI-7390|uniprotkb:D6W2R8|ensemblfungi:YOR212W	psi-mi:gbb_yeast(display_long)|uniprotkb:YOR50-2(orf name)|uniprotkb:YOR212W(locus name)|uniprotkb:STE4(gene name)|psi-mi:STE4(display_short)	psi-mi:gbb_yeast(display_long)|uniprotkb:YOR50-2(orf name)|uniprotkb:YOR212W(locus name)|uniprotkb:STE4(gene name)|psi-mi:STE4(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Slessareva et al. (2006)	imex:IM-11946|pubmed:16839886	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-973887|imex:IM-11946-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005738|refseq:NP_014855.3|mint:P18851|dip:DIP-954N|ensemblfungi:YOR212W(gene)|ensemblfungi:YOR212W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005937"(mating projection)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0043577"(chemotropism)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|go:"GO:1903260"(protein localization to mating projection tip)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1SCG|reactome:R-SCE-6814122	sgd:S000005738|refseq:NP_014855.3|mint:P18851|dip:DIP-954N|ensemblfungi:YOR212W(gene)|ensemblfungi:YOR212W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005937"(mating projection)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0043577"(chemotropism)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|go:"GO:1903260"(protein localization to mating projection tip)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1SCG|reactome:R-SCE-6814122	psi-mi:"MI:0469"(intact)	crc64:4B0E26040AAA83E5	crc64:4B0E26040AAA83E5	figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/19	2014/10/16	rogid:nDgadSWQPcmSvQlIEjpNHPl3Hjc559292	rogid:nDgadSWQPcmSvQlIEjpNHPl3Hjc559292	intact-crc:305770FE7787AA1A|rigid:yYg93nhHKLvtNF6UbUhSLF1wo4g	false	calmodulin binding peptide plus protein a tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P22543	uniprotkb:P08539	intact:EBI-20405|uniprotkb:D6VYN8|ensemblfungi:YLR240W	intact:EBI-7376|uniprotkb:D3DKU8|ensemblfungi:YHR005C	psi-mi:vps34_yeast(display_long)|uniprotkb:VPS34(gene name)|psi-mi:VPS34(display_short)|uniprotkb:END12(gene name synonym)|uniprotkb:PEP15(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 34(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 29(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 15(gene name synonym)|uniprotkb:VPL7(gene name synonym)|uniprotkb:VPT29(gene name synonym)|uniprotkb:L9672.10(orf name)|uniprotkb:YLR240W(locus name)	psi-mi:gpa1_yeast(display_long)|uniprotkb:YHR005C(locus name)|uniprotkb:GPA1(gene name)|psi-mi:GPA1(display_short)|uniprotkb:CDC70(gene name synonym)|uniprotkb:DAC1(gene name synonym)|uniprotkb:SCG1(gene name synonym)|uniprotkb:GP1-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Slessareva et al. (2006)	imex:IM-11946|pubmed:16839886	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-973922|imex:IM-11946-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013341.1|sgd:S000004230|ensemblfungi:YLR240W(gene)|ensemblfungi:YLR240W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:2001159"(regulation of protein localization by the Cvt pathway)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|rcsb pdb:5DFZ|rcsb pdb:5KC2|reactome:R-SCE-1632852|reactome:R-SCE-1660514|reactome:R-SCE-1660516|reactome:R-SCE-1660517|reactome:R-SCE-5668599|dip:DIP-97N|mint:P22543	refseq:NP_011868.1|sgd:S000001047|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-416482|dip:DIP-15N|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|ensemblfungi:YHR005C(gene)|ensemblfungi:YHR005C_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071701"(regulation of MAPK export from nucleus)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:1SCG|rcsb pdb:7AD3	psi-mi:"MI:0469"(intact)	crc64:806E3404EF260287	crc64:2E87C546E133D6E5	figure legend:4|agonist:Interaction was increased in the presence of AIF4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/19	2014/10/16	rogid:a8TnZYg+pKpfjIhB9uInf8Y0uOw559292	rogid:SxuqaRpicb7ZBsQju2vD6C8h3X4559292	intact-crc:BE29A3C6D91BF301|rigid:Zkd9V1H/z5/F/R6EekAyMKBdRqU	false	glutathione s tranferase tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P08539	uniprotkb:P22219	intact:EBI-7376|uniprotkb:D3DKU8|ensemblfungi:YHR005C	intact:EBI-20347|uniprotkb:D6VQ98|ensemblfungi:YBR097W	psi-mi:gpa1_yeast(display_long)|uniprotkb:YHR005C(locus name)|uniprotkb:GPA1(gene name)|psi-mi:GPA1(display_short)|uniprotkb:CDC70(gene name synonym)|uniprotkb:DAC1(gene name synonym)|uniprotkb:SCG1(gene name synonym)|uniprotkb:GP1-alpha(gene name synonym)	psi-mi:vps15_yeast(display_long)|uniprotkb:VPS15(gene name)|psi-mi:VPS15(display_short)|uniprotkb:GRD8(gene name synonym)|uniprotkb:VPL19(gene name synonym)|uniprotkb:YBR0825(orf name)|uniprotkb:YBR097W(locus name)|uniprotkb:VAC4(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 15(gene name synonym)|uniprotkb:Golgi-retention defective mutant protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Slessareva et al. (2006)	imex:IM-11946|pubmed:16839886	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-973929|imex:IM-11946-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011868.1|sgd:S000001047|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-416482|dip:DIP-15N|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|ensemblfungi:YHR005C(gene)|ensemblfungi:YHR005C_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071701"(regulation of MAPK export from nucleus)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:1SCG|rcsb pdb:7AD3	refseq:NP_009655.2|sgd:S000000301|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071561"(nucleus-vacuole junction)|ensemblfungi:YBR097W(gene)|go:"GO:0106310"(protein serine kinase activity)|ensemblfungi:YBR097W_mRNA(transcript)|go:"GO:0106311"|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|rcsb pdb:3GRE|rcsb pdb:5DFZ|rcsb pdb:5KC2|reactome:R-SCE-1632852|reactome:R-SCE-1660514|reactome:R-SCE-1660516|reactome:R-SCE-1660517|reactome:R-SCE-5668599|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|dip:DIP-814N|mint:P22219	psi-mi:"MI:0469"(intact)	crc64:2E87C546E133D6E5	crc64:247EBA5531E41FFB	figure legend:4|antagonist:Decreased interaction was observed in the presence of Aif4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/19	2014/10/16	rogid:SxuqaRpicb7ZBsQju2vD6C8h3X4559292	rogid:bDKA6IlevNTmtSQqleAbkY7/eAI559292	intact-crc:A16458231A33E71D|rigid:tWAdwaeCRy/IxzICw2Uyg1j0TB4	false	his tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P08539	uniprotkb:P22543	intact:EBI-7376|uniprotkb:D3DKU8|ensemblfungi:YHR005C	intact:EBI-20405|uniprotkb:D6VYN8|ensemblfungi:YLR240W	psi-mi:gpa1_yeast(display_long)|uniprotkb:YHR005C(locus name)|uniprotkb:GPA1(gene name)|psi-mi:GPA1(display_short)|uniprotkb:CDC70(gene name synonym)|uniprotkb:DAC1(gene name synonym)|uniprotkb:SCG1(gene name synonym)|uniprotkb:GP1-alpha(gene name synonym)	psi-mi:vps34_yeast(display_long)|uniprotkb:VPS34(gene name)|psi-mi:VPS34(display_short)|uniprotkb:END12(gene name synonym)|uniprotkb:PEP15(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 34(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 29(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 15(gene name synonym)|uniprotkb:VPL7(gene name synonym)|uniprotkb:VPT29(gene name synonym)|uniprotkb:L9672.10(orf name)|uniprotkb:YLR240W(locus name)	psi-mi:"MI:0416"(fluorescence microscopy)	Slessareva et al. (2006)	imex:IM-11946|pubmed:16839886	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-974009|imex:IM-11946-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011868.1|sgd:S000001047|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-416482|dip:DIP-15N|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|ensemblfungi:YHR005C(gene)|ensemblfungi:YHR005C_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071701"(regulation of MAPK export from nucleus)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:1SCG|rcsb pdb:7AD3	refseq:NP_013341.1|sgd:S000004230|ensemblfungi:YLR240W(gene)|ensemblfungi:YLR240W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:2001159"(regulation of protein localization by the Cvt pathway)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR008290(Phosphatidylinositol 3-kinase, Vps34 type)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR035892|interpro:IPR036940|rcsb pdb:5DFZ|rcsb pdb:5KC2|reactome:R-SCE-1632852|reactome:R-SCE-1660514|reactome:R-SCE-1660516|reactome:R-SCE-1660517|reactome:R-SCE-5668599|dip:DIP-97N|mint:P22543	go:"GO:0005768"(endosome)	crc64:2E87C546E133D6E5	crc64:806E3404EF260287	figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/19	2014/10/16	rogid:SxuqaRpicb7ZBsQju2vD6C8h3X4559292	rogid:a8TnZYg+pKpfjIhB9uInf8Y0uOw559292	intact-crc:E3C8265B61F9F6A1|rigid:Zkd9V1H/z5/F/R6EekAyMKBdRqU	false	mutation:323-323|red fluorescent protein tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39929	uniprotkb:P08539	intact:EBI-17554|uniprotkb:D6VY27|ensemblfungi:YLR025W|uniprotkb:E9P8V6	intact:EBI-7376|uniprotkb:D3DKU8|ensemblfungi:YHR005C	psi-mi:snf7_yeast(display_long)|uniprotkb:SNF7(gene name)|psi-mi:SNF7(display_short)|uniprotkb:VPS32(gene name synonym)|uniprotkb:YLR025W(locus name)|uniprotkb:DID1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)|uniprotkb:DOA4-independent degradation protein 1(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 7(gene name synonym)	psi-mi:gpa1_yeast(display_long)|uniprotkb:YHR005C(locus name)|uniprotkb:GPA1(gene name)|psi-mi:GPA1(display_short)|uniprotkb:CDC70(gene name synonym)|uniprotkb:DAC1(gene name synonym)|uniprotkb:SCG1(gene name synonym)|uniprotkb:GP1-alpha(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Slessareva et al. (2006)	imex:IM-11946|pubmed:16839886	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-974019|imex:IM-11946-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013125.1|sgd:S000004015|ensemblfungi:YLR025W(gene)|ensemblfungi:YLR025W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1904669"(ATP export)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:5FD7|rcsb pdb:5FD9|rcsb pdb:5T8L|rcsb pdb:5T8N|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1747N|mint:P39929	refseq:NP_011868.1|sgd:S000001047|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-416482|dip:DIP-15N|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|ensemblfungi:YHR005C(gene)|ensemblfungi:YHR005C_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071701"(regulation of MAPK export from nucleus)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:1SCG|rcsb pdb:7AD3	go:"GO:0005768"(endosome)	crc64:5241A18BB181F0C1	crc64:2E87C546E133D6E5	figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/19	2014/10/16	rogid:I8qBtNlqTjxLX1HginTOzM3o9oA559292	rogid:SxuqaRpicb7ZBsQju2vD6C8h3X4559292	intact-crc:4FB54A55D6A4A452|rigid:bvhHdScXFwGTQwembHtt0rI2lgc	false	green fluorescent protein tag:?-?	mutation:323-323|red fluorescent protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P08539	uniprotkb:P39929	intact:EBI-7376|uniprotkb:D3DKU8|ensemblfungi:YHR005C	intact:EBI-17554|uniprotkb:D6VY27|ensemblfungi:YLR025W|uniprotkb:E9P8V6	psi-mi:gpa1_yeast(display_long)|uniprotkb:YHR005C(locus name)|uniprotkb:GPA1(gene name)|psi-mi:GPA1(display_short)|uniprotkb:CDC70(gene name synonym)|uniprotkb:DAC1(gene name synonym)|uniprotkb:SCG1(gene name synonym)|uniprotkb:GP1-alpha(gene name synonym)	psi-mi:snf7_yeast(display_long)|uniprotkb:SNF7(gene name)|psi-mi:SNF7(display_short)|uniprotkb:VPS32(gene name synonym)|uniprotkb:YLR025W(locus name)|uniprotkb:DID1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)|uniprotkb:DOA4-independent degradation protein 1(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 7(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Slessareva et al. (2006)	imex:IM-11946|pubmed:16839886	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-974043|imex:IM-11946-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011868.1|sgd:S000001047|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-416482|dip:DIP-15N|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|ensemblfungi:YHR005C(gene)|ensemblfungi:YHR005C_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071701"(regulation of MAPK export from nucleus)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:1SCG|rcsb pdb:7AD3	refseq:NP_013125.1|sgd:S000004015|ensemblfungi:YLR025W(gene)|ensemblfungi:YLR025W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1904669"(ATP export)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:5FD7|rcsb pdb:5FD9|rcsb pdb:5T8L|rcsb pdb:5T8N|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1747N|mint:P39929	go:"GO:0005768"(endosome)	crc64:2E87C546E133D6E5	crc64:5241A18BB181F0C1	figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/19	2014/10/16	rogid:SxuqaRpicb7ZBsQju2vD6C8h3X4559292	rogid:I8qBtNlqTjxLX1HginTOzM3o9oA559292	intact-crc:6532C7CD7D4BE71E|rigid:bvhHdScXFwGTQwembHtt0rI2lgc	false	green fluorescent protein tag:?-?|mutation:323-323	red fluorescent protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)