#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q32KD4 uniprotkb:Q8SY33 intact:EBI-105513|ensemblmetazoa:FBpp0086738|ensemblmetazoa:FBpp0086739|ensemblmetazoa:FBpp0294043 intact:EBI-160693|uniprotkb:Q8MSF0|uniprotkb:Q9V4F1|ensemblmetazoa:FBpp0088165|ensemblmetazoa:FBpp0088166|ensemblmetazoa:FBpp0088169|ensemblmetazoa:FBpp0088170 psi-mi:q32kd4_drome(display_long)|uniprotkb:AGO1(gene name)|psi-mi:AGO1(display_short)|uniprotkb:AGO1-RC(gene name synonym)|uniprotkb:Ago-1(gene name synonym)|uniprotkb:Ago1(gene name synonym)|uniprotkb:Agp1(gene name synonym)|uniprotkb:Dm Ago1(gene name synonym)|uniprotkb:DmAgo1(gene name synonym)|uniprotkb:Dmel\CG6671(gene name synonym)|uniprotkb:MRE20(gene name synonym)|uniprotkb:ago1(gene name synonym)|uniprotkb:ago1-1(gene name synonym)|uniprotkb:anon-WO0257455.29(gene name synonym)|uniprotkb:argonaute1(gene name synonym)|uniprotkb:dAGO1(gene name synonym)|uniprotkb:dAgo1(gene name synonym)|uniprotkb:"l(2)04845"(gene name synonym)|uniprotkb:AGO-1(gene name synonym)|uniprotkb:Ago(gene name synonym)|uniprotkb:"l(2)4845"(gene name synonym)|uniprotkb:"l(2)k00208"(gene name synonym)|uniprotkb:CG6671(orf name)|uniprotkb:Dmel_CG6671(orf name)|uniprotkb:"l(2)k08121"(gene name synonym)|uniprotkb:dmAgo1(gene name synonym) psi-mi:gawky_drome(display_long)|uniprotkb:gw(gene name)|psi-mi:gw(display_short)|uniprotkb:GW182(gene name synonym)|uniprotkb:CG31992(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Behm-Ansmant et al. (2006) pubmed:16815998|imex:IM-19246 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-983159|imex:IM-19246-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_725341.1|refseq:NP_725342.1|flybase:FBgn0262739|refseq:NP_001246314.1|dip:DIP-59685N|ensemblmetazoa:FBgn0262739(gene)|ensemblmetazoa:FBtr0087612(transcript)|ensemblmetazoa:FBtr0087613(transcript)|ensemblmetazoa:FBtr0305592(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0046959"(habituation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0090328"(regulation of olfactory learning)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q32KD4|rcsb pdb:1R4K|reactome:R-DME-203927|reactome:R-DME-426486|reactome:R-DME-426496|reactome:R-DME-5578749 refseq:NP_726596.1|refseq:NP_726597.1|refseq:NP_726600.1|refseq:NP_726601.1|flybase:FBgn0051992|ensemblmetazoa:FBgn0051992(gene)|ensemblmetazoa:FBtr0089100(transcript)|ensemblmetazoa:FBtr0089101(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0016442"(RISC complex)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035195"(gene silencing by miRNA)|ensemblmetazoa:FBtr0089097(transcript)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensemblmetazoa:FBtr0089096(transcript)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019486|interpro:IPR026805|interpro:IPR033503|interpro:IPR035979|interpro:IPR041971|rcsb pdb:2WBR|reactome:R-DME-426496|reactome:R-DME-5578749|refseq:NP_001014691.2|refseq:NP_726599.2|dip:DIP-35525N - - - figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2006/08/08 2014/10/16 rogid:YFcWf96n43RSnrWBGXlQpgi4Yvs7227 rogid:o3IBBvI5WirM5CVgi5nl9TT4gFc7227 intact-crc:3B4DE006F6F3E2C6|rigid:joVcbwmzqb0n3rMdT+DcV91cBAI false - necessary binding region:1-592|ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8SY33 uniprotkb:Q32KD4 intact:EBI-160693|uniprotkb:Q8MSF0|uniprotkb:Q9V4F1|ensemblmetazoa:FBpp0088165|ensemblmetazoa:FBpp0088166|ensemblmetazoa:FBpp0088169|ensemblmetazoa:FBpp0088170 intact:EBI-105513|ensemblmetazoa:FBpp0086738|ensemblmetazoa:FBpp0086739|ensemblmetazoa:FBpp0294043 psi-mi:gawky_drome(display_long)|uniprotkb:gw(gene name)|psi-mi:gw(display_short)|uniprotkb:GW182(gene name synonym)|uniprotkb:CG31992(orf name) psi-mi:q32kd4_drome(display_long)|uniprotkb:AGO1(gene name)|psi-mi:AGO1(display_short)|uniprotkb:AGO1-RC(gene name synonym)|uniprotkb:Ago-1(gene name synonym)|uniprotkb:Ago1(gene name synonym)|uniprotkb:Agp1(gene name synonym)|uniprotkb:Dm Ago1(gene name synonym)|uniprotkb:DmAgo1(gene name synonym)|uniprotkb:Dmel\CG6671(gene name synonym)|uniprotkb:MRE20(gene name synonym)|uniprotkb:ago1(gene name synonym)|uniprotkb:ago1-1(gene name synonym)|uniprotkb:anon-WO0257455.29(gene name synonym)|uniprotkb:argonaute1(gene name synonym)|uniprotkb:dAGO1(gene name synonym)|uniprotkb:dAgo1(gene name synonym)|uniprotkb:"l(2)04845"(gene name synonym)|uniprotkb:AGO-1(gene name synonym)|uniprotkb:Ago(gene name synonym)|uniprotkb:"l(2)4845"(gene name synonym)|uniprotkb:"l(2)k00208"(gene name synonym)|uniprotkb:CG6671(orf name)|uniprotkb:Dmel_CG6671(orf name)|uniprotkb:"l(2)k08121"(gene name synonym)|uniprotkb:dmAgo1(gene name synonym) psi-mi:"MI:0096"(pull down) Behm-Ansmant et al. (2006) pubmed:16815998|imex:IM-19246 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-983851|imex:IM-19246-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_726596.1|refseq:NP_726597.1|refseq:NP_726600.1|refseq:NP_726601.1|flybase:FBgn0051992|ensemblmetazoa:FBgn0051992(gene)|ensemblmetazoa:FBtr0089100(transcript)|ensemblmetazoa:FBtr0089101(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0016442"(RISC complex)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035195"(gene silencing by miRNA)|ensemblmetazoa:FBtr0089097(transcript)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensemblmetazoa:FBtr0089096(transcript)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019486|interpro:IPR026805|interpro:IPR033503|interpro:IPR035979|interpro:IPR041971|rcsb pdb:2WBR|reactome:R-DME-426496|reactome:R-DME-5578749|refseq:NP_001014691.2|refseq:NP_726599.2|dip:DIP-35525N refseq:NP_725341.1|refseq:NP_725342.1|flybase:FBgn0262739|refseq:NP_001246314.1|dip:DIP-59685N|ensemblmetazoa:FBgn0262739(gene)|ensemblmetazoa:FBtr0087612(transcript)|ensemblmetazoa:FBtr0087613(transcript)|ensemblmetazoa:FBtr0305592(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0046959"(habituation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0090328"(regulation of olfactory learning)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q32KD4|rcsb pdb:1R4K|reactome:R-DME-203927|reactome:R-DME-426486|reactome:R-DME-426496|reactome:R-DME-5578749 - - - figure legend:3H|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/08/08 2014/10/16 rogid:o3IBBvI5WirM5CVgi5nl9TT4gFc7227 rogid:YFcWf96n43RSnrWBGXlQpgi4Yvs7227 intact-crc:C1FF6F5BF11A9661|rigid:joVcbwmzqb0n3rMdT+DcV91cBAI false sufficient binding region:1-592|glutathione s tranferase tag:?-? necessary binding region:714-984(IPR003165)|35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q32KD4 uniprotkb:Q8SY33 intact:EBI-105513|ensemblmetazoa:FBpp0086738|ensemblmetazoa:FBpp0086739|ensemblmetazoa:FBpp0294043 intact:EBI-160693|uniprotkb:Q8MSF0|uniprotkb:Q9V4F1|ensemblmetazoa:FBpp0088165|ensemblmetazoa:FBpp0088166|ensemblmetazoa:FBpp0088169|ensemblmetazoa:FBpp0088170 psi-mi:q32kd4_drome(display_long)|uniprotkb:AGO1(gene name)|psi-mi:AGO1(display_short)|uniprotkb:AGO1-RC(gene name synonym)|uniprotkb:Ago-1(gene name synonym)|uniprotkb:Ago1(gene name synonym)|uniprotkb:Agp1(gene name synonym)|uniprotkb:Dm Ago1(gene name synonym)|uniprotkb:DmAgo1(gene name synonym)|uniprotkb:Dmel\CG6671(gene name synonym)|uniprotkb:MRE20(gene name synonym)|uniprotkb:ago1(gene name synonym)|uniprotkb:ago1-1(gene name synonym)|uniprotkb:anon-WO0257455.29(gene name synonym)|uniprotkb:argonaute1(gene name synonym)|uniprotkb:dAGO1(gene name synonym)|uniprotkb:dAgo1(gene name synonym)|uniprotkb:"l(2)04845"(gene name synonym)|uniprotkb:AGO-1(gene name synonym)|uniprotkb:Ago(gene name synonym)|uniprotkb:"l(2)4845"(gene name synonym)|uniprotkb:"l(2)k00208"(gene name synonym)|uniprotkb:CG6671(orf name)|uniprotkb:Dmel_CG6671(orf name)|uniprotkb:"l(2)k08121"(gene name synonym)|uniprotkb:dmAgo1(gene name synonym) psi-mi:gawky_drome(display_long)|uniprotkb:gw(gene name)|psi-mi:gw(display_short)|uniprotkb:GW182(gene name synonym)|uniprotkb:CG31992(orf name) psi-mi:"MI:0663"(confocal microscopy) Behm-Ansmant et al. (2006) pubmed:16815998|imex:IM-19246 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-983890|imex:IM-19246-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_725341.1|refseq:NP_725342.1|flybase:FBgn0262739|refseq:NP_001246314.1|dip:DIP-59685N|ensemblmetazoa:FBgn0262739(gene)|ensemblmetazoa:FBtr0087612(transcript)|ensemblmetazoa:FBtr0087613(transcript)|ensemblmetazoa:FBtr0305592(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0046959"(habituation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0090328"(regulation of olfactory learning)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q32KD4|rcsb pdb:1R4K|reactome:R-DME-203927|reactome:R-DME-426486|reactome:R-DME-426496|reactome:R-DME-5578749 refseq:NP_726596.1|refseq:NP_726597.1|refseq:NP_726600.1|refseq:NP_726601.1|flybase:FBgn0051992|ensemblmetazoa:FBgn0051992(gene)|ensemblmetazoa:FBtr0089100(transcript)|ensemblmetazoa:FBtr0089101(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0016442"(RISC complex)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035195"(gene silencing by miRNA)|ensemblmetazoa:FBtr0089097(transcript)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensemblmetazoa:FBtr0089096(transcript)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019486|interpro:IPR026805|interpro:IPR033503|interpro:IPR035979|interpro:IPR041971|rcsb pdb:2WBR|reactome:R-DME-426496|reactome:R-DME-5578749|refseq:NP_001014691.2|refseq:NP_726599.2|dip:DIP-35525N - - - figure legend:3B-G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2006/08/08 2014/10/16 rogid:YFcWf96n43RSnrWBGXlQpgi4Yvs7227 rogid:o3IBBvI5WirM5CVgi5nl9TT4gFc7227 intact-crc:2E382E27985205A7|rigid:joVcbwmzqb0n3rMdT+DcV91cBAI false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)