#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q7M2R6 uniprotkb:P97346 intact:EBI-8546737|intact:MINT-2634639 intact:EBI-309684|uniprotkb:Q5H8T6|uniprotkb:Q5H8U0|uniprotkb:Q99KF3|ensembl:ENSMUSP00000021204 psi-mi:q7m2r6_bovin(display_long) psi-mi:nxn_mouse(display_long)|uniprotkb:Nxn(gene name)|psi-mi:Nxn(display_short)|uniprotkb:Gn25(gene name synonym)|uniprotkb:Protein Red-1(gene name synonym) psi-mi:"MI:0096"(pull down) Lechward et al. (2006) mint:MINT-5218732|pubmed:16764867|imex:IM-11080 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8546730|mint:MINT-2634625|imex:IM-11080-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031090|interpro:IPR021133|interpro:IPR016024(Armadillo-type fold)|mint:Q7M2R6|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|mint:MINT-2634626(identity) refseq:NP_032776.1|ensembl:ENSMUSG00000020844(gene)|ensembl:ENSMUST00000021204(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0072359"(circulatory system development)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041861|mint:P97346|mint:MINT-2634631(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/21 2014/10/16 rogid:gSdt/2C3jRieFFRxVECaiyr0fw89913 rogid:E2wolJ9L07RD67oaLen/2a3ETnU10090 intact-crc:1B4F56EFCFEF1708|rigid:Rnui7CnzJxoC01SINuba6/dgK24 false - glutathione s tranferase tag:?-?(MINT-2634636) 1 1 psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P97346 uniprotkb:P67774 intact:EBI-309684|uniprotkb:Q5H8T6|uniprotkb:Q5H8U0|uniprotkb:Q99KF3|ensembl:ENSMUSP00000021204 intact:EBI-5525987|uniprotkb:A6QLI7|uniprotkb:P05323|uniprotkb:P13197|ensembl:ENSBTAP00000000596 psi-mi:nxn_mouse(display_long)|uniprotkb:Nxn(gene name)|psi-mi:Nxn(display_short)|uniprotkb:Gn25(gene name synonym)|uniprotkb:Protein Red-1(gene name synonym) psi-mi:pp2aa_bovin(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short) psi-mi:"MI:0096"(pull down) Lechward et al. (2006) mint:MINT-5218732|pubmed:16764867|imex:IM-11080 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8546713|mint:MINT-2634605|imex:IM-11080-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032776.1|ensembl:ENSMUSG00000020844(gene)|ensembl:ENSMUST00000021204(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0072359"(circulatory system development)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041861|mint:P97346|mint:MINT-2634606(identity) refseq:NP_851374.1|ensembl:ENSBTAG00000000469(gene)|ensembl:ENSBTAT00000000596(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67774|reactome:R-BTA-1295596|reactome:R-BTA-195253|reactome:R-BTA-196299|reactome:R-BTA-198753|reactome:R-BTA-202670|reactome:R-BTA-389513|reactome:R-BTA-432142|reactome:R-BTA-5673000|reactome:R-BTA-5675221|mint:MINT-2634607(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/21 2014/10/16 rogid:E2wolJ9L07RD67oaLen/2a3ETnU10090 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9913 intact-crc:373719BBB08A1416|rigid:EM6+fFec4IR5EKpKK6Q1kxGVkTg false glutathione s tranferase tag:?-?(MINT-2634613) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P30153 uniprotkb:P97346 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-309684|uniprotkb:Q5H8T6|uniprotkb:Q5H8U0|uniprotkb:Q99KF3|ensembl:ENSMUSP00000021204 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:nxn_mouse(display_long)|uniprotkb:Nxn(gene name)|psi-mi:Nxn(display_short)|uniprotkb:Gn25(gene name synonym)|uniprotkb:Protein Red-1(gene name synonym) psi-mi:"MI:0096"(pull down) Lechward et al. (2006) mint:MINT-5218732|pubmed:16764867|imex:IM-11080 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8546779|mint:MINT-2634668|imex:IM-11080-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N|mint:MINT-2634669(identity) refseq:NP_032776.1|ensembl:ENSMUSG00000020844(gene)|ensembl:ENSMUST00000021204(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0072359"(circulatory system development)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041861|mint:P97346|mint:MINT-2634675(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/21 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:E2wolJ9L07RD67oaLen/2a3ETnU10090 intact-crc:3A9BEEB443C39F5C|rigid:Whf9IQkaNXJGBAPjRlUdva3d4gU false - glutathione s tranferase tag:?-?(MINT-2634680)|binding-associated region:162-435(MINT-2634728) 1 1 psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P97346 uniprotkb:P67775 intact:EBI-309684|uniprotkb:Q5H8T6|uniprotkb:Q5H8U0|uniprotkb:Q99KF3|ensembl:ENSMUSP00000021204 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:nxn_mouse(display_long)|uniprotkb:Nxn(gene name)|psi-mi:Nxn(display_short)|uniprotkb:Gn25(gene name synonym)|uniprotkb:Protein Red-1(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0096"(pull down) Lechward et al. (2006) mint:MINT-5218732|pubmed:16764867|imex:IM-11080 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8546757|mint:MINT-2634647|imex:IM-11080-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032776.1|ensembl:ENSMUSG00000020844(gene)|ensembl:ENSMUST00000021204(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0072359"(circulatory system development)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041861|mint:P97346|mint:MINT-2634653(identity) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N|mint:MINT-2634648(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/21 2014/10/16 rogid:E2wolJ9L07RD67oaLen/2a3ETnU10090 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:815A37F018C4CFCB|rigid:ENCnEbTx4fvrGaoBPhTporpuL/Q false binding-associated region:162-435(MINT-2634725)|glutathione s tranferase tag:?-?(MINT-2634654) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P97346 uniprotkb:P30153 intact:EBI-309684|uniprotkb:Q5H8T6|uniprotkb:Q5H8U0|uniprotkb:Q99KF3|ensembl:ENSMUSP00000021204 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:nxn_mouse(display_long)|uniprotkb:Nxn(gene name)|psi-mi:Nxn(display_short)|uniprotkb:Gn25(gene name synonym)|uniprotkb:Protein Red-1(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lechward et al. (2006) mint:MINT-5218732|pubmed:16764867|imex:IM-11080 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8546811|mint:MINT-2634685|imex:IM-11080-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032776.1|ensembl:ENSMUSG00000020844(gene)|ensembl:ENSMUST00000021204(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0072359"(circulatory system development)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041861|mint:P97346|mint:MINT-2634692(identity) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N|mint:MINT-2634686(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/06/21 2014/10/16 rogid:E2wolJ9L07RD67oaLen/2a3ETnU10090 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:FEF0C360CB4518D6|rigid:Whf9IQkaNXJGBAPjRlUdva3d4gU false ha tag:?-?(MINT-2634693) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P97346 uniprotkb:P67775 intact:EBI-309684|uniprotkb:Q5H8T6|uniprotkb:Q5H8U0|uniprotkb:Q99KF3|ensembl:ENSMUSP00000021204 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:nxn_mouse(display_long)|uniprotkb:Nxn(gene name)|psi-mi:Nxn(display_short)|uniprotkb:Gn25(gene name synonym)|uniprotkb:Protein Red-1(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lechward et al. (2006) mint:MINT-5218732|pubmed:16764867|imex:IM-11080 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8546829|mint:MINT-2634707|imex:IM-11080-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032776.1|ensembl:ENSMUSG00000020844(gene)|ensembl:ENSMUST00000021204(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0072359"(circulatory system development)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041861|mint:P97346|mint:MINT-2634714(identity) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N|mint:MINT-2634708(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/06/21 2014/10/16 rogid:E2wolJ9L07RD67oaLen/2a3ETnU10090 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:0F6A470991877CB2|rigid:ENCnEbTx4fvrGaoBPhTporpuL/Q false ha tag:?-?(MINT-2634719) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0086"(polyclonal antibody western blot)