#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P46459 uniprotkb:O75899 intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2 intact:EBI-715469|uniprotkb:O75974|uniprotkb:O75975|uniprotkb:Q5VXZ2|uniprotkb:Q8WX04|uniprotkb:Q9P1R2|uniprotkb:Q9UNR1|uniprotkb:Q9UNS9|ensembl:ENSP00000259455 psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short) psi-mi:gabr2_human(display_long)|uniprotkb:G-protein coupled receptor 51(gene name synonym)|uniprotkb:HG20(gene name synonym)|uniprotkb:GABBR2(gene name)|psi-mi:GABBR2(display_short)|uniprotkb:GPR51(gene name synonym)|uniprotkb:GPRC3B(gene name synonym) psi-mi:"MI:0018"(two hybrid) Pontier et al. (2006) mint:MINT-5218685|pubmed:16724110|imex:IM-11253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8530768|mint:MINT-2791609|imex:IM-11253-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2|mint:MINT-2791611(identity) refseq:NP_005449.5|ensembl:ENSG00000136928(gene)|ensembl:ENST00000259455(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004965"(G protein-coupled GABA receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0038039"(G protein-coupled receptor heterodimeric complex)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0150099"(neuron-glial cell signaling)|go:"GO:1902710"(GABA receptor complex)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR002455(GPCR, family 3, gamma-aminobutyric acid receptor, type B)|interpro:IPR002457(GPCR, family 3, gamma-aminobutyric acid receptor, type B2)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR041689|mint:O75899|rcsb pdb:4F11|rcsb pdb:4F12|rcsb pdb:4MQE|rcsb pdb:4MQF|rcsb pdb:4MR7|rcsb pdb:4MR8|rcsb pdb:4MR9|rcsb pdb:4MRM|rcsb pdb:4MS1|rcsb pdb:4MS3|rcsb pdb:4MS4|rcsb pdb:4PAS|rcsb pdb:6M8R|rcsb pdb:6OCP|rcsb pdb:6UO8|rcsb pdb:6UO9|rcsb pdb:6UOA|rcsb pdb:6VJM|rcsb pdb:6W2X|rcsb pdb:6WIV|rcsb pdb:7C7Q|rcsb pdb:7C7S|rcsb pdb:7CA3|rcsb pdb:7CA5|rcsb pdb:7CUM|rcsb pdb:7EB2|reactome:R-HSA-1296041|reactome:R-HSA-418594|reactome:R-HSA-420499|reactome:R-HSA-977444|reactome:R-HSA-997272|dip:DIP-42851N|mint:MINT-2791610(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/07/14 2014/10/16 rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606 rogid:vJ8ADZ7mdufBs4z/z0Zy4TzN3Sw9606 intact-crc:A1532FA12F025B9E|rigid:ItOVlDvOCcWe34RoxA8Jb+Bwodo false tag:?-?(MINT-2791683) binding-associated region:799-825(MINT-2791621)|tag:?-?(MINT-2791613) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P42262 uniprotkb:P46459 intact:EBI-3909876|intact:EBI-28976597|uniprotkb:Q96FP6|uniprotkb:A8MT92|uniprotkb:I6L997|ensembl:ENSP00000264426 intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2 psi-mi:gria2_human(display_long)|uniprotkb:GRIA2(gene name)|psi-mi:GRIA2(display_short)|uniprotkb:GLUR2(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 2(gene name synonym)|uniprotkb:GluR-B(gene name synonym)|uniprotkb:GluR-K2(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 2(gene name synonym) psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short) psi-mi:"MI:0096"(pull down) Pontier et al. (2006) mint:MINT-5218685|pubmed:16724110|imex:IM-11253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8530829|mint:MINT-2791723|imex:IM-11253-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264426|ensembl:ENST00000296526|ensembl:ENSP00000296526|ensembl:ENST00000393815|ensembl:ENSP00000377403|ensembl:ENST00000507898|ensembl:ENSP00000426845|ensembl:ENST00000645636|ensembl:ENSP00000495569|refseq:NP_000817.2|refseq:NP_001077088.1|refseq:NP_001077089.1|refseq:XP_016863605.1|refseq:XP_016863606.1|dip:DIP-42852N|ensembl:ENSG00000120251(gene)|ensembl:ENST00000264426(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0060076"(excitatory synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098843"(postsynaptic endocytic zone)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|mint:P42262|rcsb pdb:2WJW|rcsb pdb:2WJX|rcsb pdb:2XHD|rcsb pdb:3R7X|rcsb pdb:3RN8|rcsb pdb:3RNN|rcsb pdb:3UA8|rcsb pdb:5H8S|rcsb pdb:5YBF|rcsb pdb:5YBG|rcsb pdb:5ZG0|rcsb pdb:5ZG1|rcsb pdb:5ZG2|rcsb pdb:5ZG3|reactome:R-HSA-399710|reactome:R-HSA-416993|reactome:R-HSA-438066|reactome:R-HSA-9022699|reactome:R-HSA-9620244|go:"GO:0098794"(postsynapse)|mint:MINT-2791731(identity) ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2|mint:MINT-2791724(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/14 2014/10/16 rogid:RmjRcbMpL9azjTLLhtEjdk6w9709606 rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606 intact-crc:538702185C4893E7|rigid:bdpaTtIyeQoCyW9bWHbKatrz7wk false glutathione s tranferase tag:?-?(MINT-2791737)|binding-associated region:844-853(MINT-2791732) his tag:?-?(MINT-2791727) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0113"(western blot) uniprotkb:O75899 uniprotkb:P46459 intact:EBI-715469|uniprotkb:O75974|uniprotkb:O75975|uniprotkb:Q5VXZ2|uniprotkb:Q8WX04|uniprotkb:Q9P1R2|uniprotkb:Q9UNR1|uniprotkb:Q9UNS9|ensembl:ENSP00000259455 intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2 psi-mi:gabr2_human(display_long)|uniprotkb:G-protein coupled receptor 51(gene name synonym)|uniprotkb:HG20(gene name synonym)|uniprotkb:GABBR2(gene name)|psi-mi:GABBR2(display_short)|uniprotkb:GPR51(gene name synonym)|uniprotkb:GPRC3B(gene name synonym) psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short) psi-mi:"MI:0096"(pull down) Pontier et al. (2006) mint:MINT-5218685|pubmed:16724110|imex:IM-11253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8530802|mint:MINT-2791693|imex:IM-11253-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005449.5|ensembl:ENSG00000136928(gene)|ensembl:ENST00000259455(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004965"(G protein-coupled GABA receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0038039"(G protein-coupled receptor heterodimeric complex)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0150099"(neuron-glial cell signaling)|go:"GO:1902710"(GABA receptor complex)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR002455(GPCR, family 3, gamma-aminobutyric acid receptor, type B)|interpro:IPR002457(GPCR, family 3, gamma-aminobutyric acid receptor, type B2)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR041689|mint:O75899|rcsb pdb:4F11|rcsb pdb:4F12|rcsb pdb:4MQE|rcsb pdb:4MQF|rcsb pdb:4MR7|rcsb pdb:4MR8|rcsb pdb:4MR9|rcsb pdb:4MRM|rcsb pdb:4MS1|rcsb pdb:4MS3|rcsb pdb:4MS4|rcsb pdb:4PAS|rcsb pdb:6M8R|rcsb pdb:6OCP|rcsb pdb:6UO8|rcsb pdb:6UO9|rcsb pdb:6UOA|rcsb pdb:6VJM|rcsb pdb:6W2X|rcsb pdb:6WIV|rcsb pdb:7C7Q|rcsb pdb:7C7S|rcsb pdb:7CA3|rcsb pdb:7CA5|rcsb pdb:7CUM|rcsb pdb:7EB2|reactome:R-HSA-1296041|reactome:R-HSA-418594|reactome:R-HSA-420499|reactome:R-HSA-977444|reactome:R-HSA-997272|dip:DIP-42851N|mint:MINT-2791702(identity) ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2|mint:MINT-2791694(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2A|figure legend:F2B|figure legend:F2C|comment:"Conditions favoring NSF ATPase activity (ATP and Mg2+) disrupted the association, whereas its inhibition (ATPgammaS+Mg2+, ATP+EDTA or ATP+Mg2++EDTA) favored the interaction with GBR2ct."|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/14 2014/10/16 rogid:vJ8ADZ7mdufBs4z/z0Zy4TzN3Sw9606 rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606 intact-crc:71522B49294B46DD|rigid:ItOVlDvOCcWe34RoxA8Jb+Bwodo false glutathione s tranferase tag:?-?(MINT-2791710)|binding-associated region:799-825(MINT-2791703) his tag:?-?(MINT-2791720) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0113"(western blot) uniprotkb:P46459 uniprotkb:Q9UBS5 intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2 intact:EBI-724156|uniprotkb:Q71SG6|ensembl:ENSP00000366233|ensembl:ENSP00000373034|ensembl:ENSP00000373134|ensembl:ENSP00000388035|ensembl:ENSP00000406066|ensembl:ENSP00000411286|ensembl:ENSP00000448999|uniprotkb:Q9UQQ0|uniprotkb:O95375|uniprotkb:O95468|uniprotkb:O95975|uniprotkb:O96022|uniprotkb:Q86W60|uniprotkb:B0UXY7|uniprotkb:Q5STL4|uniprotkb:Q5SUJ8|uniprotkb:Q5SUL3 psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short) psi-mi:gabr1_human(display_long)|uniprotkb:GABBR1(gene name)|psi-mi:GABBR1(display_short)|uniprotkb:GPRC3A(gene name synonym) psi-mi:"MI:0096"(pull down) Pontier et al. (2006) mint:MINT-5218685|pubmed:16724110|imex:IM-11253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8530853|mint:MINT-2793111|imex:IM-11253-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2|mint:MINT-2793121(identity) refseq:NP_001461.1|refseq:NP_068703.1|refseq:NP_068704.2|refseq:NP_001305982.1|ensembl:ENSG00000204681(gene)|ensembl:ENSG00000206466(gene)|ensembl:ENSG00000206511(gene)|ensembl:ENSG00000232569(gene)|ensembl:ENSG00000232632(gene)|ensembl:ENSG00000237112(gene)|ensembl:ENST00000377034(transcript)|ensembl:ENST00000383542(transcript)|ensembl:ENST00000383638(transcript)|ensembl:ENST00000423604(transcript)|ensembl:ENST00000425097(transcript)|ensembl:ENST00000439457(transcript)|ensembl:ENST00000546913(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004965"(G protein-coupled GABA receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0038039"(G protein-coupled receptor heterodimeric complex)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099579"(G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR002455(GPCR, family 3, gamma-aminobutyric acid receptor, type B)|interpro:IPR002456(GPCR, family 3, gamma-aminobutyric acid receptor, type B1)|interpro:IPR017978|interpro:IPR028082|interpro:IPR035976|mint:Q9UBS5|rcsb pdb:4MQE|rcsb pdb:4MQF|rcsb pdb:4MR7|rcsb pdb:4MR8|rcsb pdb:4MR9|rcsb pdb:4MRM|rcsb pdb:4MS1|rcsb pdb:4MS3|rcsb pdb:4MS4|rcsb pdb:4PAS|rcsb pdb:6HKC|rcsb pdb:6UO8|rcsb pdb:6UO9|go:"GO:0005887"(integral component of plasma membrane)|rcsb pdb:6UOA|rcsb pdb:6VJM|rcsb pdb:6W2X|rcsb pdb:6W2Y|rcsb pdb:6WIV|rcsb pdb:7C7Q|rcsb pdb:7C7S|rcsb pdb:7CA3|rcsb pdb:7CA5|rcsb pdb:7CUM|rcsb pdb:7EB2|reactome:R-HSA-1296041|reactome:R-HSA-418594|reactome:R-HSA-420499|reactome:R-HSA-977444|reactome:R-HSA-997272|dip:DIP-38394N|mint:MINT-2793112(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/14 2014/10/16 rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606 rogid:HC9ZjJABHiocFy0LZoIb/oa0D7E9606 intact-crc:4923850E0CBAC602|rigid:AVyBLCbwVtoFuBY2fRG/lAENIKs false his tag:?-?(MINT-2793124) glutathione s tranferase tag:?-?(MINT-2793118)|binding-associated region:860-961(MINT-2793113) 1 1 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P46459 uniprotkb:Q9UBS5 intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2 intact:EBI-724156|uniprotkb:Q71SG6|ensembl:ENSP00000366233|ensembl:ENSP00000373034|ensembl:ENSP00000373134|ensembl:ENSP00000388035|ensembl:ENSP00000406066|ensembl:ENSP00000411286|ensembl:ENSP00000448999|uniprotkb:Q9UQQ0|uniprotkb:O95375|uniprotkb:O95468|uniprotkb:O95975|uniprotkb:O96022|uniprotkb:Q86W60|uniprotkb:B0UXY7|uniprotkb:Q5STL4|uniprotkb:Q5SUJ8|uniprotkb:Q5SUL3 psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short) psi-mi:gabr1_human(display_long)|uniprotkb:GABBR1(gene name)|psi-mi:GABBR1(display_short)|uniprotkb:GPRC3A(gene name synonym) psi-mi:"MI:0428"(imaging technique) Pontier et al. (2006) mint:MINT-5218685|pubmed:16724110|imex:IM-11253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8530887|mint:MINT-2793384|imex:IM-11253-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2|mint:MINT-2793395(identity) refseq:NP_001461.1|refseq:NP_068703.1|refseq:NP_068704.2|refseq:NP_001305982.1|ensembl:ENSG00000204681(gene)|ensembl:ENSG00000206466(gene)|ensembl:ENSG00000206511(gene)|ensembl:ENSG00000232569(gene)|ensembl:ENSG00000232632(gene)|ensembl:ENSG00000237112(gene)|ensembl:ENST00000377034(transcript)|ensembl:ENST00000383542(transcript)|ensembl:ENST00000383638(transcript)|ensembl:ENST00000423604(transcript)|ensembl:ENST00000425097(transcript)|ensembl:ENST00000439457(transcript)|ensembl:ENST00000546913(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004965"(G protein-coupled GABA receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0038039"(G protein-coupled receptor heterodimeric complex)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099579"(G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR002455(GPCR, family 3, gamma-aminobutyric acid receptor, type B)|interpro:IPR002456(GPCR, family 3, gamma-aminobutyric acid receptor, type B1)|interpro:IPR017978|interpro:IPR028082|interpro:IPR035976|mint:Q9UBS5|rcsb pdb:4MQE|rcsb pdb:4MQF|rcsb pdb:4MR7|rcsb pdb:4MR8|rcsb pdb:4MR9|rcsb pdb:4MRM|rcsb pdb:4MS1|rcsb pdb:4MS3|rcsb pdb:4MS4|rcsb pdb:4PAS|rcsb pdb:6HKC|rcsb pdb:6UO8|rcsb pdb:6UO9|go:"GO:0005887"(integral component of plasma membrane)|rcsb pdb:6UOA|rcsb pdb:6VJM|rcsb pdb:6W2X|rcsb pdb:6W2Y|rcsb pdb:6WIV|rcsb pdb:7C7Q|rcsb pdb:7C7S|rcsb pdb:7CA3|rcsb pdb:7CA5|rcsb pdb:7CUM|rcsb pdb:7EB2|reactome:R-HSA-1296041|reactome:R-HSA-418594|reactome:R-HSA-420499|reactome:R-HSA-977444|reactome:R-HSA-997272|dip:DIP-38394N|mint:MINT-2793385(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2006/07/14 2014/10/16 rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606 rogid:HC9ZjJABHiocFy0LZoIb/oa0D7E9606 intact-crc:2161C3EBDD3E1546|rigid:AVyBLCbwVtoFuBY2fRG/lAENIKs false - myc tag:?-?(MINT-2793392) 1 1 psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O75899 uniprotkb:P46459 intact:EBI-715469|uniprotkb:O75974|uniprotkb:O75975|uniprotkb:Q5VXZ2|uniprotkb:Q8WX04|uniprotkb:Q9P1R2|uniprotkb:Q9UNR1|uniprotkb:Q9UNS9|ensembl:ENSP00000259455 intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2 psi-mi:gabr2_human(display_long)|uniprotkb:G-protein coupled receptor 51(gene name synonym)|uniprotkb:HG20(gene name synonym)|uniprotkb:GABBR2(gene name)|psi-mi:GABBR2(display_short)|uniprotkb:GPR51(gene name synonym)|uniprotkb:GPRC3B(gene name synonym) psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short) psi-mi:"MI:0428"(imaging technique) Pontier et al. (2006) mint:MINT-5218685|pubmed:16724110|imex:IM-11253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8530904|mint:MINT-2793410|imex:IM-11253-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005449.5|ensembl:ENSG00000136928(gene)|ensembl:ENST00000259455(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004965"(G protein-coupled GABA receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0038039"(G protein-coupled receptor heterodimeric complex)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0150099"(neuron-glial cell signaling)|go:"GO:1902710"(GABA receptor complex)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR002455(GPCR, family 3, gamma-aminobutyric acid receptor, type B)|interpro:IPR002457(GPCR, family 3, gamma-aminobutyric acid receptor, type B2)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR041689|mint:O75899|rcsb pdb:4F11|rcsb pdb:4F12|rcsb pdb:4MQE|rcsb pdb:4MQF|rcsb pdb:4MR7|rcsb pdb:4MR8|rcsb pdb:4MR9|rcsb pdb:4MRM|rcsb pdb:4MS1|rcsb pdb:4MS3|rcsb pdb:4MS4|rcsb pdb:4PAS|rcsb pdb:6M8R|rcsb pdb:6OCP|rcsb pdb:6UO8|rcsb pdb:6UO9|rcsb pdb:6UOA|rcsb pdb:6VJM|rcsb pdb:6W2X|rcsb pdb:6WIV|rcsb pdb:7C7Q|rcsb pdb:7C7S|rcsb pdb:7CA3|rcsb pdb:7CA5|rcsb pdb:7CUM|rcsb pdb:7EB2|reactome:R-HSA-1296041|reactome:R-HSA-418594|reactome:R-HSA-420499|reactome:R-HSA-977444|reactome:R-HSA-997272|dip:DIP-42851N|mint:MINT-2793418(identity) ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2|mint:MINT-2793411(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2006/07/14 2014/10/16 rogid:vJ8ADZ7mdufBs4z/z0Zy4TzN3Sw9606 rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606 intact-crc:65A1F755CC0514E9|rigid:ItOVlDvOCcWe34RoxA8Jb+Bwodo false ha tag:?-?(MINT-2793424) his tag:?-?(MINT-2793414) 1 1 psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9UBS5 uniprotkb:P46459 intact:EBI-724156|uniprotkb:Q71SG6|ensembl:ENSP00000366233|ensembl:ENSP00000373034|ensembl:ENSP00000373134|ensembl:ENSP00000388035|ensembl:ENSP00000406066|ensembl:ENSP00000411286|ensembl:ENSP00000448999|uniprotkb:Q9UQQ0|uniprotkb:O95375|uniprotkb:O95468|uniprotkb:O95975|uniprotkb:O96022|uniprotkb:Q86W60|uniprotkb:B0UXY7|uniprotkb:Q5STL4|uniprotkb:Q5SUJ8|uniprotkb:Q5SUL3 intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2 psi-mi:gabr1_human(display_long)|uniprotkb:GABBR1(gene name)|psi-mi:GABBR1(display_short)|uniprotkb:GPRC3A(gene name synonym) psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pontier et al. (2006) mint:MINT-5218685|pubmed:16724110|imex:IM-11253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8530934|mint:MINT-2793092|imex:IM-11253-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001461.1|refseq:NP_068703.1|refseq:NP_068704.2|refseq:NP_001305982.1|ensembl:ENSG00000204681(gene)|ensembl:ENSG00000206466(gene)|ensembl:ENSG00000206511(gene)|ensembl:ENSG00000232569(gene)|ensembl:ENSG00000232632(gene)|ensembl:ENSG00000237112(gene)|ensembl:ENST00000377034(transcript)|ensembl:ENST00000383542(transcript)|ensembl:ENST00000383638(transcript)|ensembl:ENST00000423604(transcript)|ensembl:ENST00000425097(transcript)|ensembl:ENST00000439457(transcript)|ensembl:ENST00000546913(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004965"(G protein-coupled GABA receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0038039"(G protein-coupled receptor heterodimeric complex)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099579"(G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR002455(GPCR, family 3, gamma-aminobutyric acid receptor, type B)|interpro:IPR002456(GPCR, family 3, gamma-aminobutyric acid receptor, type B1)|interpro:IPR017978|interpro:IPR028082|interpro:IPR035976|mint:Q9UBS5|rcsb pdb:4MQE|rcsb pdb:4MQF|rcsb pdb:4MR7|rcsb pdb:4MR8|rcsb pdb:4MR9|rcsb pdb:4MRM|rcsb pdb:4MS1|rcsb pdb:4MS3|rcsb pdb:4MS4|rcsb pdb:4PAS|rcsb pdb:6HKC|rcsb pdb:6UO8|rcsb pdb:6UO9|go:"GO:0005887"(integral component of plasma membrane)|rcsb pdb:6UOA|rcsb pdb:6VJM|rcsb pdb:6W2X|rcsb pdb:6W2Y|rcsb pdb:6WIV|rcsb pdb:7C7Q|rcsb pdb:7C7S|rcsb pdb:7CA3|rcsb pdb:7CA5|rcsb pdb:7CUM|rcsb pdb:7EB2|reactome:R-HSA-1296041|reactome:R-HSA-418594|reactome:R-HSA-420499|reactome:R-HSA-977444|reactome:R-HSA-997272|dip:DIP-38394N|mint:MINT-2793093(identity) ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2|mint:MINT-2793101(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3A|figure legend:F5|comment:GABA stimulation disrupts the NSF/GBR complex. The NSF identifier is the human one although the experiment was conducted in CHO cells|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2006/07/14 2014/10/16 rogid:HC9ZjJABHiocFy0LZoIb/oa0D7E9606 rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606 intact-crc:26D079F556A7D240|rigid:AVyBLCbwVtoFuBY2fRG/lAENIKs false myc tag:?-?(MINT-2793097) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:O75899 uniprotkb:Q9UBS5 intact:EBI-715469|uniprotkb:O75974|uniprotkb:O75975|uniprotkb:Q5VXZ2|uniprotkb:Q8WX04|uniprotkb:Q9P1R2|uniprotkb:Q9UNR1|uniprotkb:Q9UNS9|ensembl:ENSP00000259455 intact:EBI-724156|uniprotkb:Q71SG6|ensembl:ENSP00000366233|ensembl:ENSP00000373034|ensembl:ENSP00000373134|ensembl:ENSP00000388035|ensembl:ENSP00000406066|ensembl:ENSP00000411286|ensembl:ENSP00000448999|uniprotkb:Q9UQQ0|uniprotkb:O95375|uniprotkb:O95468|uniprotkb:O95975|uniprotkb:O96022|uniprotkb:Q86W60|uniprotkb:B0UXY7|uniprotkb:Q5STL4|uniprotkb:Q5SUJ8|uniprotkb:Q5SUL3 psi-mi:gabr2_human(display_long)|uniprotkb:G-protein coupled receptor 51(gene name synonym)|uniprotkb:HG20(gene name synonym)|uniprotkb:GABBR2(gene name)|psi-mi:GABBR2(display_short)|uniprotkb:GPR51(gene name synonym)|uniprotkb:GPRC3B(gene name synonym) psi-mi:gabr1_human(display_long)|uniprotkb:GABBR1(gene name)|psi-mi:GABBR1(display_short)|uniprotkb:GPRC3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pontier et al. (2006) mint:MINT-5218685|pubmed:16724110|imex:IM-11253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8530953|mint:MINT-2793358|imex:IM-11253-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005449.5|ensembl:ENSG00000136928(gene)|ensembl:ENST00000259455(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004965"(G protein-coupled GABA receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0038039"(G protein-coupled receptor heterodimeric complex)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0150099"(neuron-glial cell signaling)|go:"GO:1902710"(GABA receptor complex)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR002455(GPCR, family 3, gamma-aminobutyric acid receptor, type B)|interpro:IPR002457(GPCR, family 3, gamma-aminobutyric acid receptor, type B2)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR041689|mint:O75899|rcsb pdb:4F11|rcsb pdb:4F12|rcsb pdb:4MQE|rcsb pdb:4MQF|rcsb pdb:4MR7|rcsb pdb:4MR8|rcsb pdb:4MR9|rcsb pdb:4MRM|rcsb pdb:4MS1|rcsb pdb:4MS3|rcsb pdb:4MS4|rcsb pdb:4PAS|rcsb pdb:6M8R|rcsb pdb:6OCP|rcsb pdb:6UO8|rcsb pdb:6UO9|rcsb pdb:6UOA|rcsb pdb:6VJM|rcsb pdb:6W2X|rcsb pdb:6WIV|rcsb pdb:7C7Q|rcsb pdb:7C7S|rcsb pdb:7CA3|rcsb pdb:7CA5|rcsb pdb:7CUM|rcsb pdb:7EB2|reactome:R-HSA-1296041|reactome:R-HSA-418594|reactome:R-HSA-420499|reactome:R-HSA-977444|reactome:R-HSA-997272|dip:DIP-42851N|mint:MINT-2793367(identity) refseq:NP_001461.1|refseq:NP_068703.1|refseq:NP_068704.2|refseq:NP_001305982.1|ensembl:ENSG00000204681(gene)|ensembl:ENSG00000206466(gene)|ensembl:ENSG00000206511(gene)|ensembl:ENSG00000232569(gene)|ensembl:ENSG00000232632(gene)|ensembl:ENSG00000237112(gene)|ensembl:ENST00000377034(transcript)|ensembl:ENST00000383542(transcript)|ensembl:ENST00000383638(transcript)|ensembl:ENST00000423604(transcript)|ensembl:ENST00000425097(transcript)|ensembl:ENST00000439457(transcript)|ensembl:ENST00000546913(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004965"(G protein-coupled GABA receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0038039"(G protein-coupled receptor heterodimeric complex)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099579"(G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0150099"(neuron-glial cell signaling)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR002455(GPCR, family 3, gamma-aminobutyric acid receptor, type B)|interpro:IPR002456(GPCR, family 3, gamma-aminobutyric acid receptor, type B1)|interpro:IPR017978|interpro:IPR028082|interpro:IPR035976|mint:Q9UBS5|rcsb pdb:4MQE|rcsb pdb:4MQF|rcsb pdb:4MR7|rcsb pdb:4MR8|rcsb pdb:4MR9|rcsb pdb:4MRM|rcsb pdb:4MS1|rcsb pdb:4MS3|rcsb pdb:4MS4|rcsb pdb:4PAS|rcsb pdb:6HKC|rcsb pdb:6UO8|rcsb pdb:6UO9|go:"GO:0005887"(integral component of plasma membrane)|rcsb pdb:6UOA|rcsb pdb:6VJM|rcsb pdb:6W2X|rcsb pdb:6W2Y|rcsb pdb:6WIV|rcsb pdb:7C7Q|rcsb pdb:7C7S|rcsb pdb:7CA3|rcsb pdb:7CA5|rcsb pdb:7CUM|rcsb pdb:7EB2|reactome:R-HSA-1296041|reactome:R-HSA-418594|reactome:R-HSA-420499|reactome:R-HSA-977444|reactome:R-HSA-997272|dip:DIP-38394N|mint:MINT-2793359(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5|comment:GABA stimulation disrupts the NSF/GBR complex.|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2006/07/14 2014/10/16 rogid:vJ8ADZ7mdufBs4z/z0Zy4TzN3Sw9606 rogid:HC9ZjJABHiocFy0LZoIb/oa0D7E9606 intact-crc:A43D51964FD48E18|rigid:PXxR8P/Zzzk4q4c21IEQ22E4E4M false ha tag:?-?(MINT-2793379) myc tag:?-?(MINT-2793362) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P46459 uniprotkb:P42262 intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2 intact:EBI-3909876|intact:EBI-28976597|uniprotkb:Q96FP6|uniprotkb:A8MT92|uniprotkb:I6L997|ensembl:ENSP00000264426 psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short) psi-mi:gria2_human(display_long)|uniprotkb:GRIA2(gene name)|psi-mi:GRIA2(display_short)|uniprotkb:GLUR2(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 2(gene name synonym)|uniprotkb:GluR-B(gene name synonym)|uniprotkb:GluR-K2(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Pontier et al. (2006) mint:MINT-5218685|pubmed:16724110|imex:IM-11253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8530984|mint:MINT-2791974|imex:IM-11253-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2|mint:MINT-2791984(identity) ensembl:ENSP00000264426|ensembl:ENST00000296526|ensembl:ENSP00000296526|ensembl:ENST00000393815|ensembl:ENSP00000377403|ensembl:ENST00000507898|ensembl:ENSP00000426845|ensembl:ENST00000645636|ensembl:ENSP00000495569|refseq:NP_000817.2|refseq:NP_001077088.1|refseq:NP_001077089.1|refseq:XP_016863605.1|refseq:XP_016863606.1|dip:DIP-42852N|ensembl:ENSG00000120251(gene)|ensembl:ENST00000264426(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0060076"(excitatory synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098843"(postsynaptic endocytic zone)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|mint:P42262|rcsb pdb:2WJW|rcsb pdb:2WJX|rcsb pdb:2XHD|rcsb pdb:3R7X|rcsb pdb:3RN8|rcsb pdb:3RNN|rcsb pdb:3UA8|rcsb pdb:5H8S|rcsb pdb:5YBF|rcsb pdb:5YBG|rcsb pdb:5ZG0|rcsb pdb:5ZG1|rcsb pdb:5ZG2|rcsb pdb:5ZG3|reactome:R-HSA-399710|reactome:R-HSA-416993|reactome:R-HSA-438066|reactome:R-HSA-9022699|reactome:R-HSA-9620244|go:"GO:0098794"(postsynapse)|mint:MINT-2791975(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5|figure legend:F3B|comment:GABA stimulation disrupts the NSF/GBR complex.The NSF identifier is the human one although the experiment was conducted in CHO cells|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2006/07/14 2014/10/16 rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606 rogid:RmjRcbMpL9azjTLLhtEjdk6w9709606 intact-crc:002394C04FFEB773|rigid:bdpaTtIyeQoCyW9bWHbKatrz7wk false - ha tag:?-?(MINT-2791981) 1 1 psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P46459 uniprotkb:O75899 intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2 intact:EBI-715469|uniprotkb:O75974|uniprotkb:O75975|uniprotkb:Q5VXZ2|uniprotkb:Q8WX04|uniprotkb:Q9P1R2|uniprotkb:Q9UNR1|uniprotkb:Q9UNS9|ensembl:ENSP00000259455 psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short) psi-mi:gabr2_human(display_long)|uniprotkb:G-protein coupled receptor 51(gene name synonym)|uniprotkb:HG20(gene name synonym)|uniprotkb:GABBR2(gene name)|psi-mi:GABBR2(display_short)|uniprotkb:GPR51(gene name synonym)|uniprotkb:GPRC3B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Pontier et al. (2006) mint:MINT-5218685|pubmed:16724110|imex:IM-11253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8531003|mint:MINT-2793071|imex:IM-11253-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2|mint:MINT-2793072(identity) refseq:NP_005449.5|ensembl:ENSG00000136928(gene)|ensembl:ENST00000259455(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004965"(G protein-coupled GABA receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0038039"(G protein-coupled receptor heterodimeric complex)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0150099"(neuron-glial cell signaling)|go:"GO:1902710"(GABA receptor complex)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR002455(GPCR, family 3, gamma-aminobutyric acid receptor, type B)|interpro:IPR002457(GPCR, family 3, gamma-aminobutyric acid receptor, type B2)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR041689|mint:O75899|rcsb pdb:4F11|rcsb pdb:4F12|rcsb pdb:4MQE|rcsb pdb:4MQF|rcsb pdb:4MR7|rcsb pdb:4MR8|rcsb pdb:4MR9|rcsb pdb:4MRM|rcsb pdb:4MS1|rcsb pdb:4MS3|rcsb pdb:4MS4|rcsb pdb:4PAS|rcsb pdb:6M8R|rcsb pdb:6OCP|rcsb pdb:6UO8|rcsb pdb:6UO9|rcsb pdb:6UOA|rcsb pdb:6VJM|rcsb pdb:6W2X|rcsb pdb:6WIV|rcsb pdb:7C7Q|rcsb pdb:7C7S|rcsb pdb:7CA3|rcsb pdb:7CA5|rcsb pdb:7CUM|rcsb pdb:7EB2|reactome:R-HSA-1296041|reactome:R-HSA-418594|reactome:R-HSA-420499|reactome:R-HSA-977444|reactome:R-HSA-997272|dip:DIP-42851N|mint:MINT-2793078(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5|figure legend:F3B|comment:GABA stimulation disrupts the NSF/GBR complex.The NSF identifier is the human one although the experiment was conducted in CHO cells|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2006/07/14 2014/10/16 rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606 rogid:vJ8ADZ7mdufBs4z/z0Zy4TzN3Sw9606 intact-crc:17E6EF1CF09B4AE6|rigid:ItOVlDvOCcWe34RoxA8Jb+Bwodo false - ha tag:?-?(MINT-2793083) 1 1 psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0113"(western blot)