#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q86UW9	uniprotkb:Q9NRR5	intact:EBI-740376|uniprotkb:Q96H69|uniprotkb:Q9H890|uniprotkb:Q9P200|uniprotkb:Q6XM88|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|uniprotkb:Q6XM87|intact:EBI-10192429|uniprotkb:Q4ZH49	intact:EBI-711226|intact:EBI-722657|uniprotkb:Q9BR98|uniprotkb:Q9UHX4|ensembl:ENSP00000357292|uniprotkb:Q5VYA1|uniprotkb:B2RAY7|uniprotkb:A6ND44|uniprotkb:Q5VYA0	psi-mi:dtx2_human(display_long)|uniprotkb:RING finger protein 58(gene name synonym)|uniprotkb:DTX2(gene name)|psi-mi:DTX2(display_short)|uniprotkb:KIAA1528(gene name synonym)|uniprotkb:RNF58(gene name synonym)|uniprotkb:Protein deltex-2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX2(gene name synonym)	psi-mi:ubql4_human(display_long)|uniprotkb:UBQLN4(gene name)|psi-mi:UBQLN4(display_short)|uniprotkb:C1orf6(gene name synonym)|uniprotkb:UBIN(gene name synonym)|uniprotkb:Ataxin-1 ubiquitin-like-interacting protein A1U(gene name synonym)|uniprotkb:Ataxin-1 interacting ubiquitin-like protein(gene name synonym)|uniprotkb:CIP75(gene name synonym)|uniprotkb:Connexin43-interacting protein of 75 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945714	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001096064.1|refseq:NP_001096065.1|refseq:NP_001096066.1|refseq:NP_065943.2|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|ensembl:ENST00000446820|ensembl:ENSP00000392545|ensembl:ENSG00000091073(gene)|ensembl:ENST00000324432(transcript)|ensembl:ENST00000413936(transcript)|ensembl:ENST00000430490(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018123|interpro:IPR018957|interpro:IPR037197|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|mint:Q86UW9|rcsb pdb:6IR0|rcsb pdb:6Y22|rcsb pdb:6Y2X|rcsb pdb:6Y3J|reactome:R-HSA-2122948|refseq:XP_011514074.1|refseq:XP_011514075.1|refseq:XP_011514076.1|refseq:XP_011514077.1|refseq:XP_005250188.1|refseq:XP_005250189.1|refseq:XP_016867212.1|refseq:XP_016867213.1|refseq:XP_016867214.1|refseq:XP_016867215.1|refseq:XP_016867216.1	refseq:NP_001291271.1|refseq:NP_064516.2|ensembl:ENSG00000160803(gene)|interpro:IPR029071|ensembl:ENST00000368309(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)	intact:EBI-956254(see-also)|intact:EBI-954830(see-also)|imex:IM-871(imex secondary)	-	-	negative:|figure legend:2 and table S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:ugnjqAbG6Ekyc8MGugCnjc9zVaI9606	rogid:H/kLIS8aSMue9jYu1Q4qTcBLt5o9606	intact-crc:1041632DEC25509D|rigid:e5vzZwUQmOOHfypKPL3V8Hc1wcY	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8N1L9	uniprotkb:P54253	intact:EBI-742695|uniprotkb:Q96EH4|uniprotkb:Q8NAF4|intact:EBI-945729|uniprotkb:Q8NAL8|ensembl:ENSP00000301887|uniprotkb:D9IC56	intact:EBI-930964|uniprotkb:Q17S02|uniprotkb:Q9UJG2|uniprotkb:Q9Y4J1|ensembl:ENSP00000244769|ensembl:ENSP00000416360	psi-mi:batf2_human(display_long)|uniprotkb:BATF2(gene name)|psi-mi:BATF2(display_short)|uniprotkb:Suppressor of AP-1 regulated by IFN(gene name synonym)	psi-mi:atx1_human(display_long)|uniprotkb:ATXN1(gene name)|psi-mi:ATXN1(display_short)|uniprotkb:ATX1(gene name synonym)|uniprotkb:SCA1(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 1 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945723	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612465.3|refseq:NP_001287736.1|refseq:NP_001287737.1|ensembl:ENSG00000168062(gene)|ensembl:ENST00000301887(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029857|dip:DIP-48662N	refseq:NP_000323.2|refseq:NP_001121636.1|dip:DIP-35353N|ensembl:ENSG00000124788(gene)|ensembl:ENST00000244769(transcript)|ensembl:ENST00000436367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016363"(nuclear matrix)|go:"GO:0034046"("poly(G) binding")|go:"GO:0035176"(social behavior)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051168"(nuclear export)|interpro:IPR003652(Ataxin, AXH region)|interpro:IPR036096|interpro:IPR040172|interpro:IPR043404|mint:P54253|rcsb pdb:1OA8|rcsb pdb:2M41|rcsb pdb:4APT|rcsb pdb:4AQP|rcsb pdb:4J2J|rcsb pdb:4J2L|rcsb pdb:6QIU	intact:EBI-955518(see-also)|imex:IM-1165(imex secondary)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:uL+kdibEI8CV/k5zjBeezZNzeAY9606	rogid:DodgC3h3y3QNOd7da7+XB/MPPfQ9606	intact-crc:E2BD6B1C441F5A08|rigid:npxd37JA8QdFM6XExvxg21mUrP0	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P54253	uniprotkb:Q86UW1	intact:EBI-930964|uniprotkb:Q17S02|uniprotkb:Q9UJG2|uniprotkb:Q9Y4J1|ensembl:ENSP00000244769|ensembl:ENSP00000416360	intact:EBI-945738|uniprotkb:Q6ZMC7|ensembl:ENSP00000296327	psi-mi:atx1_human(display_long)|uniprotkb:ATXN1(gene name)|psi-mi:ATXN1(display_short)|uniprotkb:ATX1(gene name synonym)|uniprotkb:SCA1(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 1 protein(gene name synonym)	psi-mi:osta_human(display_long)|uniprotkb:SLC51A(gene name)|psi-mi:SLC51A(display_short)|uniprotkb:OSTA(gene name synonym)|uniprotkb:Solute carrier family 51 subunit alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945743	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000323.2|refseq:NP_001121636.1|dip:DIP-35353N|ensembl:ENSG00000124788(gene)|ensembl:ENST00000244769(transcript)|ensembl:ENST00000436367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016363"(nuclear matrix)|go:"GO:0034046"("poly(G) binding")|go:"GO:0035176"(social behavior)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051168"(nuclear export)|interpro:IPR003652(Ataxin, AXH region)|interpro:IPR036096|interpro:IPR040172|interpro:IPR043404|mint:P54253|rcsb pdb:1OA8|rcsb pdb:2M41|rcsb pdb:4APT|rcsb pdb:4AQP|rcsb pdb:4J2J|rcsb pdb:4J2L|rcsb pdb:6QIU	refseq:NP_689885.4|ensembl:ENSG00000163959(gene)|ensembl:ENST00000296327(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0032782"(bile acid secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR005178(Protein of unknown function DUF300)	imex:IM-862(imex secondary)|intact:EBI-956870(see-also)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:DodgC3h3y3QNOd7da7+XB/MPPfQ9606	rogid:EetsmPeag/cVP/OrTNDGRdlglX89606	intact-crc:30A9D6E0FD955D27|rigid:Un/kR5nLJfOfgKqcP2nM01Tkt34	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P38432	uniprotkb:Q96HA8	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945762	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity)	intact:EBI-955702(see-also)|imex:IM-811(imex secondary)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606	intact-crc:7DD5E3DB1FFF425F|rigid:74Cv1NQhclaVx/zU0F+Rnt99EG0	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q16594	uniprotkb:P38432	intact:EBI-712521|ensembl:ENSP00000370193|ensembl:ENSP00000421873|ensembl:ENSP00000477611|ensembl:ENSP00000477750|ensembl:ENSP00000478935|ensembl:ENSP00000217893|uniprotkb:Q5U0D1|uniprotkb:Q9BTS1|uniprotkb:D3DWA3|intact:EBI-8645823|intact:MINT-8163548	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:taf9_human(display_long)|uniprotkb:Transcription initiation factor TFIID 31 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 32 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit G(gene name synonym)|uniprotkb:STAF31/32(gene name synonym)|uniprotkb:TAF9(gene name)|psi-mi:TAF9(display_short)|uniprotkb:TAF2G(gene name synonym)|uniprotkb:TAFII31(gene name synonym)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945773	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000217893(transcript)|ensembl:ENST00000328663(transcript)|ensembl:ENST00000506736(transcript)|ensembl:ENST00000615404(transcript)|ensembl:ENST00000616867(transcript)|ensembl:ENST00000617893(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030914"|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:0071339"(MLL1 complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q16594|rcsb pdb:6F3T|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-3214847|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|ensembl:ENSG00000273841(gene)|ensembl:ENSG00000276463(gene)|refseq:NP_001015892.1|refseq:NP_003178.1|dip:DIP-435N	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	imex:IM-696(imex secondary)|intact:EBI-955790(see-also)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:Drikn9IwpWQXbTTXGqwf1hlRNE09606	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:F9C30279F23A9735|rigid:tQLw782tpQhP4HZvyVlDdkirovo	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y3Q8	uniprotkb:P04156	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	intact:EBI-977302|ensembl:ENSP00000368752|ensembl:ENSP00000399376|ensembl:ENSP00000411599|ensembl:ENSP00000415284|uniprotkb:O60489|uniprotkb:P78446|uniprotkb:Q15216|uniprotkb:Q15221|uniprotkb:Q27H91|uniprotkb:Q8TBG0|uniprotkb:Q96E70|uniprotkb:Q9UP19|uniprotkb:Q5QPB4	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:prio_human(display_long)|uniprotkb:PrP27-30(gene name synonym)|uniprotkb:PrP33-35C(gene name synonym)|uniprotkb:ASCR(gene name synonym)|uniprotkb:PRNP(gene name)|psi-mi:PRNP(display_short)|uniprotkb:PRIP(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:ALTPRP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945783	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1	go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035690"|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|ensembl:ENSG00000171867(gene)|ensembl:ENST00000379440(transcript)|ensembl:ENST00000424424(transcript)|ensembl:ENST00000430350(transcript)|ensembl:ENST00000457586(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007049"(cell cycle)|go:"GO:0007611"(learning or memory)|go:"GO:0007616"(long-term memory)|go:"GO:0009986"(cell surface)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016234"(inclusion body)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031648"(protein destabilization)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098794"(postsynapse)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:0045121"(membrane raft)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902938"(regulation of intracellular calcium activated chloride channel activity)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903135"(cupric ion binding)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000817(Prion protein)|interpro:IPR022416|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|interpro:IPR025860|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|interpro:IPR036924|mint:P04156|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051087"(chaperone binding)|rcsb pdb:1E1G|rcsb pdb:1E1J|rcsb pdb:1E1P|rcsb pdb:1E1S|rcsb pdb:1E1U|rcsb pdb:1E1W|rcsb pdb:1FKC|rcsb pdb:1FO7|rcsb pdb:1H0L|rcsb pdb:1HJM|rcsb pdb:1HJN|rcsb pdb:1I4M|rcsb pdb:1OEH|rcsb pdb:1OEI|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1QLX|rcsb pdb:1QLZ|rcsb pdb:1QM0|rcsb pdb:1QM1|rcsb pdb:1QM2|rcsb pdb:1QM3|rcsb pdb:2IV4|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|rcsb pdb:2IV5|rcsb pdb:2IV6|rcsb pdb:2K1D|rcsb pdb:2KUN|rcsb pdb:2LBG|rcsb pdb:2LEJ|rcsb pdb:2LFT|rcsb pdb:2LSB|rcsb pdb:2LV1|rcsb pdb:2M8T|rcsb pdb:2OL9|rcsb pdb:2W9E|rcsb pdb:3HAF|rcsb pdb:3HAK|rcsb pdb:3HEQ|rcsb pdb:3HER|rcsb pdb:3HES|rcsb pdb:3HJ5|rcsb pdb:3HJX|rcsb pdb:3MD4|rcsb pdb:3MD5|rcsb pdb:3NHC|rcsb pdb:3NHD|rcsb pdb:3NVF|rcsb pdb:4DGI|rcsb pdb:4E1H|rcsb pdb:4E1I|rcsb pdb:4KML|rcsb pdb:4N9O|rcsb pdb:5L6R|rcsb pdb:5YJ4|rcsb pdb:5YJ5|rcsb pdb:6DU9|rcsb pdb:6LNI|rcsb pdb:6PQ5|rcsb pdb:6PQA|rcsb pdb:6SUZ|rcsb pdb:6SV2|rcsb pdb:6UUR|reactome:R-HSA-419037|reactome:R-HSA-9609523|refseq:NP_000302.1|refseq:NP_001073590.1|refseq:NP_001073591.1|refseq:NP_001073592.1|refseq:NP_898902.1|refseq:NP_001258490.1|dip:DIP-29933N	imex:IM-785(imex secondary)|intact:EBI-955894(see-also)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	rogid:O9dYBDKthE5DdgePny2xsDYzb989606	intact-crc:CDCA51059EBC7D1D|rigid:NLe4b816NUGE3/wEechrdk2SC8c	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15366	uniprotkb:Q96PU8	intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949	intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094	psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym)	psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945813	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440	refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:NP_001288014.1|refseq:XP_011534561.1|ensembl:ENSG00000112531(gene)|ensembl:ENST00000361752(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007286"(spermatid development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042552"(myelination)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0045202"(synapse)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952	intact:EBI-955934(see-also)|imex:IM-747(imex secondary)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606	rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606	intact-crc:4DC849FA2B15A878|rigid:MSi9jE67ZS23ejn6D0iFYA/vvLw	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60684	uniprotkb:Q16594	intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5	intact:EBI-712521|ensembl:ENSP00000370193|ensembl:ENSP00000421873|ensembl:ENSP00000477611|ensembl:ENSP00000477750|ensembl:ENSP00000478935|ensembl:ENSP00000217893|uniprotkb:Q5U0D1|uniprotkb:Q9BTS1|uniprotkb:D3DWA3|intact:EBI-8645823|intact:MINT-8163548	psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym)	psi-mi:taf9_human(display_long)|uniprotkb:Transcription initiation factor TFIID 31 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 32 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit G(gene name synonym)|uniprotkb:STAF31/32(gene name synonym)|uniprotkb:TAF9(gene name)|psi-mi:TAF9(display_short)|uniprotkb:TAF2G(gene name synonym)|uniprotkb:TAFII31(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945820	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N	ensembl:ENST00000217893(transcript)|ensembl:ENST00000328663(transcript)|ensembl:ENST00000506736(transcript)|ensembl:ENST00000615404(transcript)|ensembl:ENST00000616867(transcript)|ensembl:ENST00000617893(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030914"|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:0071339"(MLL1 complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q16594|rcsb pdb:6F3T|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-3214847|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|ensembl:ENSG00000273841(gene)|ensembl:ENSG00000276463(gene)|refseq:NP_001015892.1|refseq:NP_003178.1|dip:DIP-435N	imex:IM-760(imex secondary)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606	rogid:Drikn9IwpWQXbTTXGqwf1hlRNE09606	intact-crc:3E6D7AC8D038E478|rigid:ioQO68IGdD6MHhQfFBnYYoPdhjk	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NRR5	uniprotkb:Q7Z3S9	intact:EBI-711226|intact:EBI-722657|uniprotkb:Q9BR98|uniprotkb:Q9UHX4|ensembl:ENSP00000357292|uniprotkb:Q5VYA1|uniprotkb:B2RAY7|uniprotkb:A6ND44|uniprotkb:Q5VYA0	intact:EBI-945833|intact:EBI-2859688|uniprotkb:Q5BKT8|uniprotkb:Q5VTG9|uniprotkb:Q5XG84|uniprotkb:Q6P192|uniprotkb:Q8NC23|uniprotkb:Q8WUQ9|uniprotkb:Q96FY1|ensembl:ENSP00000354929	psi-mi:ubql4_human(display_long)|uniprotkb:UBQLN4(gene name)|psi-mi:UBQLN4(display_short)|uniprotkb:C1orf6(gene name synonym)|uniprotkb:UBIN(gene name synonym)|uniprotkb:Ataxin-1 ubiquitin-like-interacting protein A1U(gene name synonym)|uniprotkb:Ataxin-1 interacting ubiquitin-like protein(gene name synonym)|uniprotkb:CIP75(gene name synonym)|uniprotkb:Connexin43-interacting protein of 75 kDa(gene name synonym)	psi-mi:nt2na_human(display_long)|uniprotkb:NOTCH2NLA(gene name)|psi-mi:NOTCH2NLA(display_short)|uniprotkb:N2N(gene name synonym)|uniprotkb:NOTCH2NL(gene name synonym)|uniprotkb:Notch homolog 2 N-terminal-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945849	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291271.1|refseq:NP_064516.2|ensembl:ENSG00000160803(gene)|interpro:IPR029071|ensembl:ENST00000368309(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)	refseq:NP_982283.2|refseq:XP_016855384.1|refseq:XP_016855385.1|refseq:XP_016855386.1|refseq:XP_016855387.1|refseq:XP_016858537.1|refseq:XP_016858538.1|refseq:XP_016858539.1|refseq:XP_016858540.1|dip:DIP-47315N|refseq:XP_006711766.1|refseq:XP_006726418.1|ensembl:ENSG00000264343(gene)|ensembl:ENST00000362074(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|mint:Q7Z3S9	intact:EBI-950278(see-also)|imex:IM-835(imex secondary)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:H/kLIS8aSMue9jYu1Q4qTcBLt5o9606	rogid:FYOai/KkVz8zMsxjNnyZ6FNfcTU9606	intact-crc:59ECFFA3FC10B68C|rigid:rWft3IwEeE/rXnsAgVGayw0hMdw	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96RK0	uniprotkb:Q9BYW2	intact:EBI-945857|uniprotkb:Q7LGI1|uniprotkb:Q9UEG5|uniprotkb:Q9Y6T1|ensembl:ENSP00000458663	intact:EBI-945869|uniprotkb:O75397|uniprotkb:O75405|uniprotkb:Q17RW8|uniprotkb:Q5BKS9|uniprotkb:Q5QGN2|uniprotkb:Q69YI5|uniprotkb:Q6IN64|uniprotkb:Q6ZN53|uniprotkb:Q6ZS25|uniprotkb:Q8N3R0|uniprotkb:Q8TCN0|uniprotkb:Q9C0D1|uniprotkb:Q9H696|uniprotkb:Q9NZW9|ensembl:ENSP00000386759	psi-mi:cic_human(display_long)|uniprotkb:CIC(gene name)|psi-mi:CIC(display_short)|uniprotkb:KIAA0306(gene name synonym)	psi-mi:setd2_human(display_long)|uniprotkb:Protein-lysine N-methyltransferase SETD2(gene name synonym)|uniprotkb:KMT3A(gene name synonym)|uniprotkb:SET domain-containing protein 2(gene name synonym)|uniprotkb:Huntingtin-interacting protein B(gene name synonym)|uniprotkb:Huntingtin yeast partner B(gene name synonym)|uniprotkb:Huntingtin-interacting protein 1(gene name synonym)|uniprotkb:HIF-1(gene name synonym)|uniprotkb:p231HBP(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3A(gene name synonym)|uniprotkb:SETD2(gene name)|psi-mi:SETD2(display_short)|uniprotkb:HIF1(gene name synonym)|uniprotkb:HYPB(gene name synonym)|uniprotkb:KIAA1732(gene name synonym)|uniprotkb:SET2(gene name synonym)|uniprotkb:HSPC069(orf name)	psi-mi:"MI:0096"(pull down)	Lim et al. (2006)	pubmed:16713569|imex:IM-11827|mint:MINT-5218676	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-945875	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055940.3|refseq:NP_001291744.1|ensembl:ENSP00000458663|dip:DIP-49964N|ensembl:ENSG00000079432(gene)|ensembl:ENST00000575354(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0035176"(social behavior)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q96RK0|rcsb pdb:2M41|rcsb pdb:4J2J|rcsb pdb:4J2L|rcsb pdb:6JRP|rcsb pdb:6KZG|rcsb pdb:6KZH	refseq:NP_054878.5|ensembl:ENSG00000181555(gene)|ensembl:ENST00000409792(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001763"(morphogenesis of a branching structure)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006298"(mismatch repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018023"(peptidyl-lysine trimethylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0030900"(forebrain development)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034728"(nucleosome organization)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048332"(mesoderm morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0048864"(stem cell development)|go:"GO:0051607"(defense response to virus)|go:"GO:0060039"(pericardium development)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0060977"(coronary vasculature morphogenesis)|go:"GO:0097198"(histone H3-K36 trimethylation)|go:"GO:0097676"(histone H3-K36 dimethylation)|go:"GO:1902850"(microtubule cytoskeleton organization involved in mitosis)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR013257(SRI, Set2 Rpb1 interacting)|interpro:IPR035441|interpro:IPR036020|interpro:IPR038190|interpro:IPR042294|interpro:IPR044437|mint:Q9BYW2|rcsb pdb:2A7O|rcsb pdb:2MDC|rcsb pdb:2MDI|rcsb pdb:2MDJ|rcsb pdb:4FMU|rcsb pdb:4H12|rcsb pdb:5JJY|rcsb pdb:5JLB|rcsb pdb:5JLE|rcsb pdb:5LSS|rcsb pdb:5LSX|rcsb pdb:5LSY|rcsb pdb:5LSZ|rcsb pdb:5LT6|rcsb pdb:5LT7|rcsb pdb:5LT8|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:6J9J|rcsb pdb:6VDB|reactome:R-HSA-3214841	intact:EBI-952516(see-also)|imex:IM-1014(imex secondary)	-	-	figure legend:2 and table S3|negative:|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/25	2014/10/16	rogid:E3FWgv7mlzlumUUZ/Jke9JA+JeI9606	rogid:9f0NjyLj+lCSDh5yRP9lVMMepuw9606	intact-crc:417DE5602BE13565|rigid:oqM6hH1pqLT2PALCbRmDyDLlT3Y	true	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)