#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P47035	uniprotkb:Q00684	intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym)	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Queralt et al. (2006)	imex:IM-12044|pubmed:16713564	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-943948|imex:IM-12044-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	psi-mi:"MI:0469"(intact)	crc64:80EDF9A8065EB5A2	crc64:4EB3985DFA3FD823	inhibition:"Reduced interaction was observed in the absence of CDC55 (Q00362)"|figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/06/05	2014/10/16	rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	intact-crc:C9EDDC18AEF357B2|rigid:pfc6F7X5GhV4Htgws7vy7cnj5ug	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q03018	uniprotkb:Q00362	intact:EBI-6657|uniprotkb:D6VUN0|ensemblfungi:YGR098C	intact:EBI-1942|uniprotkb:D6VTW4|ensemblfungi:YGL190C	psi-mi:esp1_yeast(display_long)|uniprotkb:ESP1(gene name)|psi-mi:ESP1(display_short)|uniprotkb:YGR098C(locus name)|uniprotkb:Separase(gene name synonym)	psi-mi:2aba_yeast(display_long)|uniprotkb:CDC55(gene name)|psi-mi:CDC55(display_short)|uniprotkb:YGL190C(locus name)|uniprotkb:G1345(orf name)|uniprotkb:PR55(gene name synonym)|uniprotkb:Cell division control protein 55(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Queralt et al. (2006)	imex:IM-12044|pubmed:16713564	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-943954|imex:IM-12044-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003330|refseq:NP_011612.3|dip:DIP-2933N|mint:Q03018|ensemblfungi:YGR098C(gene)|ensemblfungi:YGR098C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006915"(apoptotic process)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|rcsb pdb:5U1S|rcsb pdb:5U1T|reactome:R-SCE-2467813	sgd:S000003158|refseq:NP_011325.1|dip:DIP-2281N|mint:Q00362|ensemblfungi:YGL190C(gene)|ensemblfungi:YGL190C_mRNA(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0061586"(positive regulation of transcription by transcription factor localization)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|reactome:R-SCE-69273|reactome:R-SCE-975957	psi-mi:"MI:0469"(intact)	-	crc64:6DA12C2805FA6A82	comment:Metaphase arested cells were used for the experiment.|figure legend:5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/06/05	2014/10/16	rogid:UMTGDO9alhQOMP7ZXNTEDs/ZB68559292	rogid:sfmW86gQWAM4FTHowXGJMjQavQA559292	intact-crc:079A9D9C8AC67B3E|rigid:imq2JPMPTWbdzyLvMNglhyhzwPI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47035	uniprotkb:P24869	intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W	intact:EBI-4515|uniprotkb:D6W4B8|ensemblfungi:YPR119W	psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym)	psi-mi:cg22_yeast(display_long)|uniprotkb:CLB2(gene name)|psi-mi:CLB2(display_short)|uniprotkb:P9642.6(orf name)|uniprotkb:YPR119W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Queralt et al. (2006)	imex:IM-12044|pubmed:16713564	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1108510|imex:IM-12044-3	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185	refseq:NP_015444.1|sgd:S000006323|mint:P24869|dip:DIP-658N|ensemblfungi:YPR119W(gene)|ensemblfungi:YPR119W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005935"(cellular bud neck)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|reactome:R-SCE-3214858|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69231|reactome:R-SCE-69656|reactome:R-SCE-75815|reactome:R-SCE-8951664|reactome:R-SCE-983168	go:"GO:0016301"(kinase activity)	crc64:80EDF9A8065EB5A2	crc64:B68FF888871022A0	figure legend:S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/06/05	2014/10/16	rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292	rogid:9pN1AHtkN1tX8cBgI7zsFYNJFQc559292	intact-crc:98201AA747C09B64|rigid:C80gwyWGWs18YbjkeItOma+fLzU	false	sufficient binding region:1-600	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)