#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P06779 uniprotkb:P31244 intact:EBI-14780|uniprotkb:D6VWM3|ensemblfungi:YJR052W intact:EBI-14645|uniprotkb:D6VQB3|ensemblfungi:YBR114W psi-mi:rad7_yeast(display_long)|uniprotkb:J1665(orf name)|uniprotkb:YJR052W(locus name)|uniprotkb:RAD7(gene name)|psi-mi:RAD7(display_short) psi-mi:rad16_yeast(display_long)|uniprotkb:RAD16(gene name)|psi-mi:RAD16(display_short)|uniprotkb:YBR114W(locus name)|uniprotkb:YBR0909(orf name)|uniprotkb:ATP-dependent helicase RAD16(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gillette et al. (2006) pubmed:16675952|imex:IM-10944|mint:MINT-5218591 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8508555|mint:MINT-2737795|imex:IM-10944-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012586.1|sgd:S000003813|ensemblfungi:YJR052W(gene)|ensemblfungi:YJR052W_mRNA(transcript)|go:"GO:0000113"(nucleotide-excision repair factor 4 complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034613"(cellular protein localization)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|rcsb pdb:5ZB2|dip:DIP-2484N|mint:P06779|mint:MINT-2737802(identity) refseq:NP_009672.1|sgd:S000000318|ensemblfungi:YBR114W(gene)|ensemblfungi:YBR114W_mRNA(transcript)|go:"GO:0000113"(nucleotide-excision repair factor 4 complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027417|interpro:IPR038718|dip:DIP-697N|mint:P31244 - crc64:85C77357DC99737A|comment:"Stoichiometry: 1.0" crc64:954317B5E85C6306 figure legend:F2A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/07/03 2017/08/08 rogid:JcNBlyir1aBQS3irlS0wpOx4ZmE559292 rogid:AnRhB3ntemSEMsUcMJ8xiV7G1mY559292 intact-crc:A41F74251947048E|rigid:wwqkSio3tROm7/zGGZStjLpmMPg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06779 uniprotkb:Q03071 intact:EBI-14780|uniprotkb:D6VWM3|ensemblfungi:YJR052W intact:EBI-30154|uniprotkb:O13292|uniprotkb:D6W3W8|ensemblfungi:YPL046C psi-mi:rad7_yeast(display_long)|uniprotkb:J1665(orf name)|uniprotkb:YJR052W(locus name)|uniprotkb:RAD7(gene name)|psi-mi:RAD7(display_short) psi-mi:eloc_yeast(display_long)|uniprotkb:ELC1(gene name)|psi-mi:ELC1(display_short)|uniprotkb:YPL046C(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gillette et al. (2006) pubmed:16675952|imex:IM-10944|mint:MINT-5218591 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8508555|mint:MINT-2737795|imex:IM-10944-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012586.1|sgd:S000003813|ensemblfungi:YJR052W(gene)|ensemblfungi:YJR052W_mRNA(transcript)|go:"GO:0000113"(nucleotide-excision repair factor 4 complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034613"(cellular protein localization)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|rcsb pdb:5ZB2|dip:DIP-2484N|mint:P06779|mint:MINT-2737802(identity) refseq:NP_015279.1|sgd:S000005967|dip:DIP-6531N|mint:Q03071|ensemblfungi:YPL046C(gene)|ensemblfungi:YPL046C_mRNA(transcript)|go:"GO:0000113"(nucleotide-excision repair factor 4 complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|rcsb pdb:1HV2|rcsb pdb:5ZB2|rcsb pdb:6R6H|rcsb pdb:6R7I|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-75955|reactome:R-SCE-983168 - crc64:85C77357DC99737A|comment:"Stoichiometry: 1.0" crc64:B77BAC75D40BD53E figure legend:F2A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/07/03 2017/08/08 rogid:JcNBlyir1aBQS3irlS0wpOx4ZmE559292 rogid:LSEKfws0L2XQB07v2/1XrMs4wUI559292 intact-crc:A41F74251947048E|rigid:wwqkSio3tROm7/zGGZStjLpmMPg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06779 uniprotkb:P53202 intact:EBI-14780|uniprotkb:D6VWM3|ensemblfungi:YJR052W intact:EBI-23065|uniprotkb:D6VUE0|ensemblfungi:YGR003W psi-mi:rad7_yeast(display_long)|uniprotkb:J1665(orf name)|uniprotkb:YJR052W(locus name)|uniprotkb:RAD7(gene name)|psi-mi:RAD7(display_short) psi-mi:cul3_yeast(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:Cullin-B(gene name synonym)|uniprotkb:YGR003W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gillette et al. (2006) pubmed:16675952|imex:IM-10944|mint:MINT-5218591 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8508555|mint:MINT-2737795|imex:IM-10944-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012586.1|sgd:S000003813|ensemblfungi:YJR052W(gene)|ensemblfungi:YJR052W_mRNA(transcript)|go:"GO:0000113"(nucleotide-excision repair factor 4 complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034613"(cellular protein localization)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|rcsb pdb:5ZB2|dip:DIP-2484N|mint:P06779|mint:MINT-2737802(identity) refseq:NP_011517.1|sgd:S000003235|dip:DIP-5506N|mint:P53202|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:YGR003W(gene)|ensemblfungi:YGR003W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|mint:MINT-2737796(identity) - crc64:85C77357DC99737A|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/07/03 2017/08/08 rogid:JcNBlyir1aBQS3irlS0wpOx4ZmE559292 rogid:FvYjEpmLA9mF35UTi97nLZwp0eE559292 intact-crc:A41F74251947048E|rigid:wwqkSio3tROm7/zGGZStjLpmMPg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P14736 uniprotkb:P06779 intact:EBI-14766|ensemblfungi:YER162C|uniprotkb:D3DM70 intact:EBI-14780|uniprotkb:D6VWM3|ensemblfungi:YJR052W psi-mi:rad4_yeast(display_long)|uniprotkb:YER162C(locus name)|uniprotkb:RAD4(gene name)|psi-mi:RAD4(display_short) psi-mi:rad7_yeast(display_long)|uniprotkb:J1665(orf name)|uniprotkb:YJR052W(locus name)|uniprotkb:RAD7(gene name)|psi-mi:RAD7(display_short) psi-mi:"MI:0415"(enzymatic study) Gillette et al. (2006) pubmed:16675952|imex:IM-10944|mint:MINT-5218591 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0220"(ubiquitination reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8508591|mint:MINT-2737829|imex:IM-10944-4 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000964|ensemblfungi:YER162C(gene)|ensemblfungi:YER162C_mRNA(transcript)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006265"(DNA topological change)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071942"(XPC complex)|go:"GO:1990165"(single-strand break-containing DNA binding)|interpro:IPR004583(DNA repair protein Rad4)|interpro:IPR018325|interpro:IPR018326|interpro:IPR018327|interpro:IPR018328|interpro:IPR036985|interpro:IPR038765|interpro:IPR042488|rcsb pdb:2M14|rcsb pdb:2QSF|rcsb pdb:2QSG|rcsb pdb:4YIR|rcsb pdb:6CFI|rcsb pdb:6UBF|rcsb pdb:6UG1|rcsb pdb:6UIN|rcsb pdb:2QSH|refseq:NP_011089.4|dip:DIP-1547N|mint:P14736|mint:MINT-2737830(identity) refseq:NP_012586.1|sgd:S000003813|ensemblfungi:YJR052W(gene)|ensemblfungi:YJR052W_mRNA(transcript)|go:"GO:0000113"(nucleotide-excision repair factor 4 complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034613"(cellular protein localization)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|rcsb pdb:5ZB2|dip:DIP-2484N|mint:P06779|mint:MINT-2737836(identity) - crc64:788D3B6F580D2BF8|comment:"Stoichiometry: 1.0" crc64:85C77357DC99737A|comment:"Stoichiometry: 1.0" figure legend:F2C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/03 2014/10/16 rogid:oWnmog8oMzIGsGz5jdPXApX/o0I559292 rogid:JcNBlyir1aBQS3irlS0wpOx4ZmE559292 intact-crc:E2F21F8ECDA6B577|rigid:UYlH89pebuVmze2AkS7SKRkslqI false - - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)