#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q02936-PRO_0000013202 uniprotkb:Q9VM64 intact:EBI-932704 intact:EBI-94134|uniprotkb:C0PTX1|uniprotkb:Q2XY56|ensemblmetazoa:FBpp0078993 psi-mi:q02936-pro_0000013202(display_long)|uniprotkb:hh(gene name)|psi-mi:hh(display_short)|uniprotkb:CG4637(orf name) psi-mi:ihog_drome(display_long)|uniprotkb:ihog(gene name)|psi-mi:ihog(display_short)|uniprotkb:CG9211(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yao et al. (2006) pubmed:16630821|imex:IM-11821 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-932694|imex:IM-11821-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-499194(chain-parent) refseq:NP_609085.1|flybase:FBgn0031872|go:"GO:0048749"(compound eye development)|go:"GO:0071694"(maintenance of protein location in extracellular region)|go:"GO:0097108"(hedgehog family protein binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2IBB|rcsb pdb:2IBG|rcsb pdb:2IC2|reactome:R-DME-209338|reactome:R-DME-376176|reactome:R-DME-428542|reactome:R-DME-447043|reactome:R-DME-525793|reactome:R-DME-5632681|reactome:R-DME-6798695|ensemblmetazoa:FBgn0031872(gene)|ensemblmetazoa:FBtr0079365(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007379"(segment specification)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035230"(cytoneme)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|dip:DIP-35774N go:"GO:0007224"(smoothened signaling pathway)|imex:IM-228(imex secondary) chain-seq-start:85|chain-seq-end:471 - comment:HhN conditioned medium was used and precipitated HhN was detected by Western blotting.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/02 2014/10/16 rogid:XHqxOsXshXwbfCmFBjvCWDqcnKs7227 rogid:wVWidrzkB+FFOM22fhmlnU4JDgQ7227 intact-crc:03976029B9521526|rigid:19pnMwXWuh3GjYZkJBQqhNu06u0 false - sufficient binding region:464..464-568..568(IPR003961) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q02936-PRO_0000013202 uniprotkb:Q9W4Y6 intact:EBI-932704 intact:EBI-109559|ensemblmetazoa:FBpp0070441|ensemblmetazoa:FBpp0292889|ensemblmetazoa:FBpp0292890 psi-mi:q02936-pro_0000013202(display_long)|uniprotkb:hh(gene name)|psi-mi:hh(display_short)|uniprotkb:CG4637(orf name) psi-mi:q9w4y6_drome(display_long)|uniprotkb:Dmel_CG32796(orf name)|uniprotkb:boi(gene name)|psi-mi:boi(display_short)|uniprotkb:boi-RB(gene name synonym)|uniprotkb:CG13756(gene name synonym)|uniprotkb:CG7894(gene name synonym)|uniprotkb:CG32796(orf name)|uniprotkb:Boi(gene name synonym)|uniprotkb:CT23737(gene name synonym)|uniprotkb:CT33235(gene name synonym)|uniprotkb:Dmel\CG32796(gene name synonym)|uniprotkb:"EG:BACH59J11.2"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yao et al. (2006) pubmed:16630821|imex:IM-11821 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-932766|imex:IM-11821-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-499194(chain-parent) refseq:NP_001188540.1|refseq:NP_001188541.1|refseq:NP_726811.1|flybase:FBgn0040388|ensemblmetazoa:FBgn0040388(gene)|ensemblmetazoa:FBtr0070457(transcript)|ensemblmetazoa:FBtr0303886(transcript)|ensemblmetazoa:FBtr0303887(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|reactome:R-DME-209338 imex:IM-229(imex secondary)|go:"GO:0007224"(smoothened signaling pathway) chain-seq-start:85|chain-seq-end:471 - comment:Boi in PBS was used and precipitated HhN was detected by Western blotting.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/02 2014/10/16 rogid:XHqxOsXshXwbfCmFBjvCWDqcnKs7227 rogid:V76jOzYdC5SypEN2Xmv845D4+jE7227 intact-crc:CF6C50CC73E0AB8A|rigid:GAO1fdcj9dAwVKZIKEzndesWCWA false - sufficient binding region:467..467-524..595(IPR003961) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)