#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q79V62	uniprotkb:Q79V62	intact:EBI-701584|uniprotkb:Q8RR35|ensemblbacteria:BAC08033	intact:EBI-701584|uniprotkb:Q8RR35|ensemblbacteria:BAC08033	psi-mi:kaia_theeb(display_long)|uniprotkb:kaiA(gene name)|psi-mi:kaiA(display_short)|uniprotkb:tlr0481(locus name)	psi-mi:kaia_theeb(display_long)|uniprotkb:kaiA(gene name)|psi-mi:kaiA(display_short)|uniprotkb:tlr0481(locus name)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Pattanayek et al. (2006)	pubmed:16628225|mint:MINT-5218542|imex:IM-11244	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-934174|imex:IM-11244-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_681271.1|refseq:WP_011056332.1|dip:DIP-29355N|mint:Q79V62|ensemblbacteria:BAC08033(gene)|ensemblbacteria:BAC08033(transcript)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042802"(identical protein binding)|interpro:IPR011006(CheY-like)|interpro:IPR011648(KaiA)|interpro:IPR017944|interpro:IPR020844|interpro:IPR020856|rcsb pdb:1Q6A|rcsb pdb:1Q6B|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:1V2Z|rcsb pdb:5JWR	refseq:NP_681271.1|refseq:WP_011056332.1|dip:DIP-29355N|mint:Q79V62|ensemblbacteria:BAC08033(gene)|ensemblbacteria:BAC08033(transcript)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042802"(identical protein binding)|interpro:IPR011006(CheY-like)|interpro:IPR011648(KaiA)|interpro:IPR017944|interpro:IPR020844|interpro:IPR020856|rcsb pdb:1Q6A|rcsb pdb:1Q6B|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:1V2Z|rcsb pdb:5JWR	-	crc64:D3B0DCBE8A580B4E	crc64:D3B0DCBE8A580B4E	dataset:Cyanobacteria - Interaction dataset based on Cyanobacteria proteins and related species|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/05	2014/10/16	rogid:CeRDujd+nzKBpU7pTDOvj5aG1aQ197221	rogid:CeRDujd+nzKBpU7pTDOvj5aG1aQ197221	intact-crc:F8F4928D89D4FCFC|rigid:UZVAXyXMapbMEJCK8i5uQbwiJZQ	false	his tag:?-?	his tag:?-?	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6L8K1	uniprotkb:Q6L8K1	intact:EBI-934195	intact:EBI-934195	psi-mi:kaia_thevl(display_long)|uniprotkb:kaiA(gene name)|psi-mi:kaiA(display_short)	psi-mi:kaia_thevl(display_long)|uniprotkb:kaiA(gene name)|psi-mi:kaiA(display_short)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Pattanayek et al. (2006)	pubmed:16628225|mint:MINT-5218542|imex:IM-11244	taxid:32053(thevl)|taxid:32053(Thermosynechococcus vulcanus)	taxid:32053(thevl)|taxid:32053(Thermosynechococcus vulcanus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-934201|imex:IM-11244-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011006(CheY-like)|interpro:IPR011648(KaiA)|interpro:IPR020844|interpro:IPR020856|interpro:IPR017944|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007623"(circadian rhythm)	interpro:IPR011006(CheY-like)|interpro:IPR011648(KaiA)|interpro:IPR020844|interpro:IPR020856|interpro:IPR017944|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007623"(circadian rhythm)	-	-	-	dataset:Cyanobacteria - Interaction dataset based on Cyanobacteria proteins and related species|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/05	2014/10/16	rogid:ozW5HsNTP+dpeHasHUKVbP/tacI32053	rogid:ozW5HsNTP+dpeHasHUKVbP/tacI32053	intact-crc:5740AD8F1DAD68ED|rigid:/6ZcI1QCW3vcn7qViBpWHm4o/PE	false	his tag:?-?	his tag:?-?	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6L8J9	uniprotkb:Q6L8J9	intact:EBI-934214	intact:EBI-934214	psi-mi:kaic_thevl(display_long)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:kaic_thevl(display_long)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Pattanayek et al. (2006)	pubmed:16628225|mint:MINT-5218542|imex:IM-11244	taxid:32053(thevl)|taxid:32053(Thermosynechococcus vulcanus)	taxid:32053(thevl)|taxid:32053(Thermosynechococcus vulcanus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-934220|imex:IM-11244-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR030665|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR027417|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	interpro:IPR030665|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR027417|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	-	-	stimulant:hexamerization was induced by addition of AMPPNP.|dataset:Cyanobacteria - Interaction dataset based on Cyanobacteria proteins and related species|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/05	2014/10/16	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o32053	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o32053	intact-crc:5C792C427A366ED1|rigid:lHIn5cCqqkTH2hglffxz5f4yG9g	false	his tag:?-?	his tag:?-?	6	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6L8K1	uniprotkb:Q6L8J9	intact:EBI-934195	intact:EBI-934214	psi-mi:kaia_thevl(display_long)|uniprotkb:kaiA(gene name)|psi-mi:kaiA(display_short)	psi-mi:kaic_thevl(display_long)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Pattanayek et al. (2006)	pubmed:16628225|mint:MINT-5218542|imex:IM-11244	taxid:32053(thevl)|taxid:32053(Thermosynechococcus vulcanus)	taxid:32053(thevl)|taxid:32053(Thermosynechococcus vulcanus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-934223|imex:IM-11244-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011006(CheY-like)|interpro:IPR011648(KaiA)|interpro:IPR020844|interpro:IPR020856|interpro:IPR017944|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007623"(circadian rhythm)	interpro:IPR030665|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR027417|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	-	-	comment:Unlike Synechoccus elongatus KaiC, Thermosynechoccus KaiC can be purified as monomer. Thus Phosphorylation with ATP and hexamerization with AMPPNP can be performed separetely making isolation of a stable KaiA-KaiC complex possible.|comment:The c-terminal 25 amino-acids linker of KaiC is necessary for kaiA dimer binding to KaiC hexamer.|dataset:Cyanobacteria - Interaction dataset based on Cyanobacteria proteins and related species|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/05	2014/10/16	rogid:ozW5HsNTP+dpeHasHUKVbP/tacI32053	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o32053	intact-crc:ECA2BC0ACBCBCC90|rigid:keOzvo84h11grZaNUbeS6XGF8qw	false	his tag:?-?	his tag:?-?|necessary binding region:493-518	2	6	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q79V60	uniprotkb:Q79V60	intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035	intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035	psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Pattanayek et al. (2006)	pubmed:16628225|mint:MINT-5218542|imex:IM-11244	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-934227|imex:IM-11244-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61	refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61	-	crc64:34E4CDF9DE9C1824	crc64:34E4CDF9DE9C1824	stimulant:Hexamerization was induced by addition of AMPPNP.|dataset:Cyanobacteria - Interaction dataset based on Cyanobacteria proteins and related species|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/05	2014/10/16	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221	intact-crc:D7EB78ADECD0D2E3|rigid:J34Cs6aVH71mufKg+r4ucWerICo	false	his tag:?-?	his tag:?-?	6	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q79V60	uniprotkb:Q79V60	intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035	intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035	psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Pattanayek et al. (2006)	pubmed:16628225|mint:MINT-5218542|imex:IM-11244	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-934263|imex:IM-11244-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61	refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61	-	crc64:34E4CDF9DE9C1824	crc64:34E4CDF9DE9C1824	stimulant:Hexamerization was induced by addition of ATP.|comment:KaiC c-terminus deletion which impairs circadian rythm in vivo does not the kaiC hexamer formation in vitro.|dataset:Cyanobacteria - Interaction dataset based on Cyanobacteria proteins and related species|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/05	2014/10/16	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221	intact-crc:1D8F12AB51FF8D18|rigid:J34Cs6aVH71mufKg+r4ucWerICo	false	his tag:?-?	his tag:?-?	6	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6L8J9	uniprotkb:Q6L8K1	intact:EBI-934214	intact:EBI-934195	psi-mi:kaic_thevl(display_long)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:kaia_thevl(display_long)|uniprotkb:kaiA(gene name)|psi-mi:kaiA(display_short)	psi-mi:"MI:0040"(electron microscopy)	Pattanayek et al. (2006)	pubmed:16628225|mint:MINT-5218542|imex:IM-11244	taxid:32053(thevl)|taxid:32053(Thermosynechococcus vulcanus)	taxid:32053(thevl)|taxid:32053(Thermosynechococcus vulcanus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-934279|imex:IM-11244-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR030665|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR027417|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	interpro:IPR011006(CheY-like)|interpro:IPR011648(KaiA)|interpro:IPR020844|interpro:IPR020856|interpro:IPR017944|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007623"(circadian rhythm)	-	-	-	comment:Unlike Synechoccus elongatus KaiC, Thermosynechoccus KaiC can be purified as monomer. Thus Phosphorylation with ATP and hexamerization with AMPPNP can be performed separetely making isolation of a stable KaiA-KaiC complex possible.|comment:The c-terminal 25 amino-acids linker of KaiC is necessary for kaiA dimer binding to KaiC hexamer.|dataset:Cyanobacteria - Interaction dataset based on Cyanobacteria proteins and related species|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/05	2014/10/16	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o32053	rogid:ozW5HsNTP+dpeHasHUKVbP/tacI32053	intact-crc:7F9540FA1BEC4994|rigid:keOzvo84h11grZaNUbeS6XGF8qw	false	necessary binding region:493-518|his tag:?-?	his tag:?-?	6	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6L8J9	uniprotkb:Q6L8J9	intact:EBI-934214	intact:EBI-934214	psi-mi:kaic_thevl(display_long)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:kaic_thevl(display_long)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:"MI:0040"(electron microscopy)	Pattanayek et al. (2006)	pubmed:16628225|mint:MINT-5218542|imex:IM-11244	taxid:32053(thevl)|taxid:32053(Thermosynechococcus vulcanus)	taxid:32053(thevl)|taxid:32053(Thermosynechococcus vulcanus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-934289|imex:IM-11244-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR030665|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR027417|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	interpro:IPR030665|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR027417|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	-	-	stimulant:hexamerization was induced by addition of AMPPNP.|dataset:Cyanobacteria - Interaction dataset based on Cyanobacteria proteins and related species|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/05	2014/10/16	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o32053	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o32053	intact-crc:B961FE648F0B0F46|rigid:lHIn5cCqqkTH2hglffxz5f4yG9g	false	his tag:?-?	his tag:?-?	6	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q79V60	uniprotkb:Q79V60	intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035	intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035	psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:"MI:0040"(electron microscopy)	Pattanayek et al. (2006)	pubmed:16628225|mint:MINT-5218542|imex:IM-11244	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-934294|imex:IM-11244-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61	refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61	-	crc64:34E4CDF9DE9C1824	crc64:34E4CDF9DE9C1824	stimulant:Hexamerization was induced by addition of AMPPNP.|dataset:Cyanobacteria - Interaction dataset based on Cyanobacteria proteins and related species|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/05	2014/10/16	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221	intact-crc:3CFFD11831E4CA0B|rigid:J34Cs6aVH71mufKg+r4ucWerICo	false	his tag:?-?	his tag:?-?	6	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)