#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q91VH1	uniprotkb:Q9UKG1	intact:EBI-992398|uniprotkb:Q9CZA0|ensembl:ENSMUSP00000027727|ensembl:ENSMUSP00000107856	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	psi-mi:paqr1_mouse(display_long)|uniprotkb:Adipor1(gene name)|psi-mi:Adipor1(display_short)|uniprotkb:Parq1(gene name synonym)|uniprotkb:Progestin and adipoQ receptor family member 1(gene name synonym)|uniprotkb:Progestin and adipoQ receptor family member I(gene name synonym)	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Mao et al. (2006)	imex:IM-14533|pubmed:16622416	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-992141|imex:IM-14533-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_082596.2|refseq:NP_001292998.1|ensembl:ENSMUSG00000026457(gene)|ensembl:ENSMUST00000027727(transcript)|ensembl:ENSMUST00000112237(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0055100"(adiponectin binding)|go:"GO:0097003"(adipokinetic hormone receptor activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR004254(Hly-III related)|reactome:R-MMU-163680	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N	psi-mi:"MI:0469"(intact)	-	-	comment:The C terminus coordinates of the binding region of Dip13b was not given in the text|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/08/18	2014/10/16	rogid:sRBu/UH4wy3WuzP2dHQoo17u2Ts10090	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	intact-crc:2DD82127166D9192|rigid:Oj5q3kspnDBpU6qW+FdVSJ+2p90	false	sufficient binding region:4-142	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKG1	uniprotkb:Q91VH1	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-992398|uniprotkb:Q9CZA0|ensembl:ENSMUSP00000027727|ensembl:ENSMUSP00000107856	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:paqr1_mouse(display_long)|uniprotkb:Adipor1(gene name)|psi-mi:Adipor1(display_short)|uniprotkb:Parq1(gene name synonym)|uniprotkb:Progestin and adipoQ receptor family member 1(gene name synonym)|uniprotkb:Progestin and adipoQ receptor family member I(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Mao et al. (2006)	imex:IM-14533|pubmed:16622416	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-992311|imex:IM-14533-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N	refseq:NP_082596.2|refseq:NP_001292998.1|ensembl:ENSMUSG00000026457(gene)|ensembl:ENSMUST00000027727(transcript)|ensembl:ENSMUST00000112237(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0055100"(adiponectin binding)|go:"GO:0097003"(adipokinetic hormone receptor activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR004254(Hly-III related)|reactome:R-MMU-163680	psi-mi:"MI:0469"(intact)	-	-	figure legend:Figure 1a|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/08/18	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:sRBu/UH4wy3WuzP2dHQoo17u2Ts10090	intact-crc:3F231E6318AB94E0|rigid:Oj5q3kspnDBpU6qW+FdVSJ+2p90	false	sufficient binding region:455-631	sufficient binding region:4-142	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UKG1	uniprotkb:Q91VH1	intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9	intact:EBI-992398|uniprotkb:Q9CZA0|ensembl:ENSMUSP00000027727|ensembl:ENSMUSP00000107856	psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym)	psi-mi:paqr1_mouse(display_long)|uniprotkb:Adipor1(gene name)|psi-mi:Adipor1(display_short)|uniprotkb:Parq1(gene name synonym)|uniprotkb:Progestin and adipoQ receptor family member 1(gene name synonym)|uniprotkb:Progestin and adipoQ receptor family member I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Mao et al. (2006)	imex:IM-14533|pubmed:16622416	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-992376|imex:IM-14533-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N	refseq:NP_082596.2|refseq:NP_001292998.1|ensembl:ENSMUSG00000026457(gene)|ensembl:ENSMUST00000027727(transcript)|ensembl:ENSMUST00000112237(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0055100"(adiponectin binding)|go:"GO:0097003"(adipokinetic hormone receptor activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR004254(Hly-III related)|reactome:R-MMU-163680	psi-mi:"MI:0469"(intact)	-	-	figure legend:Figure 1d|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast)	-	2006/08/18	2014/10/16	rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606	rogid:sRBu/UH4wy3WuzP2dHQoo17u2Ts10090	intact-crc:E8A6E1FDB0261D32|rigid:Oj5q3kspnDBpU6qW+FdVSJ+2p90	false	glutathione s tranferase tag:?-?|sufficient binding region:455-693	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8K3G9	uniprotkb:Q91VH1	intact:EBI-647007|uniprotkb:Q99LT7|ensembl:ENSMUSP00000020500	intact:EBI-992398|uniprotkb:Q9CZA0|ensembl:ENSMUSP00000027727|ensembl:ENSMUSP00000107856	psi-mi:dp13b_mouse(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 2(gene name synonym)|uniprotkb:Appl2(gene name)|psi-mi:Appl2(display_short)|uniprotkb:Dip13b(gene name synonym)|uniprotkb:Dip3b(gene name synonym)	psi-mi:paqr1_mouse(display_long)|uniprotkb:Adipor1(gene name)|psi-mi:Adipor1(display_short)|uniprotkb:Parq1(gene name synonym)|uniprotkb:Progestin and adipoQ receptor family member 1(gene name synonym)|uniprotkb:Progestin and adipoQ receptor family member I(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mao et al. (2006)	imex:IM-14533|pubmed:16622416	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-992422|imex:IM-14533-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_660255.1|ensembl:ENSMUSG00000020263(gene)|ensembl:ENSMUST00000020500(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009631"(cold acclimation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036186"(early phagosome membrane)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|go:"GO:0042803"(protein homodimerization activity)	refseq:NP_082596.2|refseq:NP_001292998.1|ensembl:ENSMUSG00000026457(gene)|ensembl:ENSMUST00000027727(transcript)|ensembl:ENSMUST00000112237(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0055100"(adiponectin binding)|go:"GO:0097003"(adipokinetic hormone receptor activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR004254(Hly-III related)|reactome:R-MMU-163680	psi-mi:"MI:0469"(intact)	-	-	figure legend:Figure 1e|agonist:adiponectin|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast)	-	2006/08/18	2014/10/16	rogid:wd57HQ8H/qlUZQ3kRbY5nhqnJ/Y10090	rogid:sRBu/UH4wy3WuzP2dHQoo17u2Ts10090	intact-crc:244A5773CA51CA6E|rigid:HW1dVOlsx5rYrNZ8oqFVcnAyuHw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)