#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:E9Q5G7 uniprotkb:Q03385 intact:EBI-923698|uniprotkb:Q810D9|ensembl:ENSMUSP00000093165 intact:EBI-923705|uniprotkb:Q8R077|ensembl:ENSMUSP00000028170 psi-mi:oog1_mouse(display_long)|uniprotkb:Oog1(gene name)|psi-mi:Oog1(display_short)|uniprotkb:Oog(gene name synonym) psi-mi:gnds_mouse(display_long)|uniprotkb:Ralgds(gene name)|psi-mi:Ralgds(display_short)|uniprotkb:Rgds(gene name synonym)|uniprotkb:Ral guanine nucleotide exchange factor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsukamoto et al. (2006) pubmed:16580637|imex:IM-19876 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-923717|imex:IM-19876-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_848772.3|ensembl:ENSMUSG00000096576(gene)|ensembl:ENSMUST00000095509(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048599"(oocyte development)|interpro:IPR026271|interpro:IPR032675 refseq:NP_033084.2|ensembl:ENSMUSG00000026821(gene)|ensembl:ENSMUST00000028170(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0030695"(GTPase regulator activity)|interpro:IPR000159(Ras-association)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR015758(Guanine nucleotide dissociation stimulator RalGDS)|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036964|reactome:R-MMU-171007|reactome:R-MMU-5673001 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/04/06 2016/09/27 rogid:YbncJFkwe8QEcT4BXIhm18Ip45c10090 rogid:a0U+a2utTyp+AKh2I6+/H0tixn410090 intact-crc:5FFDF4DF6F761103|rigid:cGkNJ8h7sEAzj8HbyUcy8AkHywk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E9Q5G7 uniprotkb:Q03385 intact:EBI-923698|uniprotkb:Q810D9|ensembl:ENSMUSP00000093165 intact:EBI-923705|uniprotkb:Q8R077|ensembl:ENSMUSP00000028170 psi-mi:oog1_mouse(display_long)|uniprotkb:Oog1(gene name)|psi-mi:Oog1(display_short)|uniprotkb:Oog(gene name synonym) psi-mi:gnds_mouse(display_long)|uniprotkb:Ralgds(gene name)|psi-mi:Ralgds(display_short)|uniprotkb:Rgds(gene name synonym)|uniprotkb:Ral guanine nucleotide exchange factor(gene name synonym) psi-mi:"MI:0096"(pull down) Tsukamoto et al. (2006) pubmed:16580637|imex:IM-19876 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-923727|imex:IM-19876-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_848772.3|ensembl:ENSMUSG00000096576(gene)|ensembl:ENSMUST00000095509(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048599"(oocyte development)|interpro:IPR026271|interpro:IPR032675 refseq:NP_033084.2|ensembl:ENSMUSG00000026821(gene)|ensembl:ENSMUST00000028170(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0030695"(GTPase regulator activity)|interpro:IPR000159(Ras-association)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR015758(Guanine nucleotide dissociation stimulator RalGDS)|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036964|reactome:R-MMU-171007|reactome:R-MMU-5673001 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/06 2016/09/27 rogid:YbncJFkwe8QEcT4BXIhm18Ip45c10090 rogid:a0U+a2utTyp+AKh2I6+/H0tixn410090 intact-crc:BA3CE9D9372A0AD4|rigid:cGkNJ8h7sEAzj8HbyUcy8AkHywk false - glutathione s tranferase tag:?-?|sufficient binding region:735-852 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:E9Q5G7 uniprotkb:Q4FJP3 intact:EBI-923698|uniprotkb:Q810D9|ensembl:ENSMUSP00000093165 intact:EBI-923822 psi-mi:oog1_mouse(display_long)|uniprotkb:Oog1(gene name)|psi-mi:Oog1(display_short)|uniprotkb:Oog(gene name synonym) psi-mi:q4fjp3_mouse(display_long)|uniprotkb:Nras(gene name)|psi-mi:Nras(display_short) psi-mi:"MI:0096"(pull down) Tsukamoto et al. (2006) pubmed:16580637|imex:IM-19876 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-923818|imex:IM-19876-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_848772.3|ensembl:ENSMUSG00000096576(gene)|ensembl:ENSMUST00000095509(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048599"(oocyte development)|interpro:IPR026271|interpro:IPR032675 refseq:NP_035067.2|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR020849|interpro:IPR027417|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane) - - - comment:Oog1 specifically interacts with Ras in a GTP-dependent manner.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/06 2016/09/27 rogid:YbncJFkwe8QEcT4BXIhm18Ip45c10090 rogid:aPsbcN7Rd/mSBu3cxVapqK991L010090 intact-crc:DA5DAB37FEBC29E8|rigid:MRluF3w9/mtWDLbR36CHnKH4BvY false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03385 uniprotkb:E9Q5G7 intact:EBI-923705|uniprotkb:Q8R077|ensembl:ENSMUSP00000028170 intact:EBI-923698|uniprotkb:Q810D9|ensembl:ENSMUSP00000093165 psi-mi:gnds_mouse(display_long)|uniprotkb:Ralgds(gene name)|psi-mi:Ralgds(display_short)|uniprotkb:Rgds(gene name synonym)|uniprotkb:Ral guanine nucleotide exchange factor(gene name synonym) psi-mi:oog1_mouse(display_long)|uniprotkb:Oog1(gene name)|psi-mi:Oog1(display_short)|uniprotkb:Oog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tsukamoto et al. (2006) pubmed:16580637|imex:IM-19876 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-923741|imex:IM-19876-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033084.2|ensembl:ENSMUSG00000026821(gene)|ensembl:ENSMUST00000028170(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0030695"(GTPase regulator activity)|interpro:IPR000159(Ras-association)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR015758(Guanine nucleotide dissociation stimulator RalGDS)|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036964|reactome:R-MMU-171007|reactome:R-MMU-5673001 refseq:NP_848772.3|ensembl:ENSMUSG00000096576(gene)|ensembl:ENSMUST00000095509(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048599"(oocyte development)|interpro:IPR026271|interpro:IPR032675 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/04/06 2016/09/27 rogid:a0U+a2utTyp+AKh2I6+/H0tixn410090 rogid:YbncJFkwe8QEcT4BXIhm18Ip45c10090 intact-crc:34F0C3B09233C5A4|rigid:cGkNJ8h7sEAzj8HbyUcy8AkHywk false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03385 uniprotkb:E9Q5G7 intact:EBI-923705|uniprotkb:Q8R077|ensembl:ENSMUSP00000028170 intact:EBI-923698|uniprotkb:Q810D9|ensembl:ENSMUSP00000093165 psi-mi:gnds_mouse(display_long)|uniprotkb:Ralgds(gene name)|psi-mi:Ralgds(display_short)|uniprotkb:Rgds(gene name synonym)|uniprotkb:Ral guanine nucleotide exchange factor(gene name synonym) psi-mi:oog1_mouse(display_long)|uniprotkb:Oog1(gene name)|psi-mi:Oog1(display_short)|uniprotkb:Oog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsukamoto et al. (2006) pubmed:16580637|imex:IM-19876 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-923762|imex:IM-19876-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033084.2|ensembl:ENSMUSG00000026821(gene)|ensembl:ENSMUST00000028170(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0030695"(GTPase regulator activity)|interpro:IPR000159(Ras-association)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR015758(Guanine nucleotide dissociation stimulator RalGDS)|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036964|reactome:R-MMU-171007|reactome:R-MMU-5673001 refseq:NP_848772.3|ensembl:ENSMUSG00000096576(gene)|ensembl:ENSMUST00000095509(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048599"(oocyte development)|interpro:IPR026271|interpro:IPR032675 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/04/06 2016/09/27 rogid:a0U+a2utTyp+AKh2I6+/H0tixn410090 rogid:YbncJFkwe8QEcT4BXIhm18Ip45c10090 intact-crc:D4BD02342E2D27C4|rigid:cGkNJ8h7sEAzj8HbyUcy8AkHywk false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03385 uniprotkb:E9Q5G7 intact:EBI-923705|uniprotkb:Q8R077|ensembl:ENSMUSP00000028170 intact:EBI-923698|uniprotkb:Q810D9|ensembl:ENSMUSP00000093165 psi-mi:gnds_mouse(display_long)|uniprotkb:Ralgds(gene name)|psi-mi:Ralgds(display_short)|uniprotkb:Rgds(gene name synonym)|uniprotkb:Ral guanine nucleotide exchange factor(gene name synonym) psi-mi:oog1_mouse(display_long)|uniprotkb:Oog1(gene name)|psi-mi:Oog1(display_short)|uniprotkb:Oog(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Tsukamoto et al. (2006) pubmed:16580637|imex:IM-19876 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-923784|imex:IM-19876-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033084.2|ensembl:ENSMUSG00000026821(gene)|ensembl:ENSMUST00000028170(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0030695"(GTPase regulator activity)|interpro:IPR000159(Ras-association)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR015758(Guanine nucleotide dissociation stimulator RalGDS)|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036964|reactome:R-MMU-171007|reactome:R-MMU-5673001 refseq:NP_848772.3|ensembl:ENSMUSG00000096576(gene)|ensembl:ENSMUST00000095509(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048599"(oocyte development)|interpro:IPR026271|interpro:IPR032675 go:"GO:0005634"(nucleus)|go:"GO:0051170"(import into nucleus) - - comment:Interaction of Oog1 and Ralgds was colocalised to the nucleus. Interaction of Oog1 and Ralgds sequestered Ralgds to the nucleus.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/04/06 2016/09/27 rogid:a0U+a2utTyp+AKh2I6+/H0tixn410090 rogid:YbncJFkwe8QEcT4BXIhm18Ip45c10090 intact-crc:E246DF0941A6AFF8|rigid:cGkNJ8h7sEAzj8HbyUcy8AkHywk false myc tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)