#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q68CJ9 uniprotkb:P18850 intact:EBI-852194|uniprotkb:Q6ZMC5|uniprotkb:Q96TB9|uniprotkb:B2R7S6|uniprotkb:B7ZL69|uniprotkb:M0QYW7|ensembl:ENSP00000078445 intact:EBI-852157|uniprotkb:O15139|uniprotkb:Q5VW62|uniprotkb:Q6IPB5|uniprotkb:Q9UEC9|ensembl:ENSP00000356919|ensembl:ENSP00000505025|ensembl:ENSP00000505998 psi-mi:cr3l3_human(display_long)|uniprotkb:Transcription factor CREB-H(gene name synonym)|uniprotkb:CREB3L3(gene name)|psi-mi:CREB3L3(display_short)|uniprotkb:CREBH(gene name synonym)|uniprotkb:HYST1481(orf name) psi-mi:atf6a_human(display_long)|uniprotkb:Activating transcription factor 6 alpha(gene name synonym)|uniprotkb:ATF6(gene name)|psi-mi:ATF6(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2006) pubmed:16469704|imex:IM-11834 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-852192|imex:IM-11834-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115996.1|refseq:NP_001258925.1|refseq:NP_001258926.1|refseq:NP_001258924.1|ensembl:ENSG00000060566(gene)|ensembl:ENST00000078445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002675"(positive regulation of acute inflammatory response)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029806|reactome:R-HSA-8874211|reactome:R-HSA-8963889 refseq:NP_031374.2|dip:DIP-29304N|ensembl:ENSG00000118217(gene)|ensembl:ENST00000367942(transcript)|ensembl:ENST00000681738(transcript)|ensembl:ENST00000681801(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903893"(positive regulation of ATF6-mediated unfolded protein response)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029801|mint:P18850|reactome:R-HSA-380994|reactome:R-HSA-381033|reactome:R-HSA-381183|go:"GO:0030968"(endoplasmic reticulum unfolded protein response) imex:IM-1408(imex secondary) - - agonist:interaction observed in the presence of Tm|delivery method:Q68CJ9 transfection|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/02/14 2014/10/16 rogid:axewrbgxxLtbhwgtdJ4haLjlr7w9606 rogid:mIU7Apng6rQ423SQnZTsceVSRus9606 intact-crc:1A84CFE269C0FD43|rigid:60YDTVpjDHWXGCgynwFHm9GHZJU false binding-associated region:1-321|flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q68CJ9 uniprotkb:P18850 intact:EBI-852194|uniprotkb:Q6ZMC5|uniprotkb:Q96TB9|uniprotkb:B2R7S6|uniprotkb:B7ZL69|uniprotkb:M0QYW7|ensembl:ENSP00000078445 intact:EBI-852157|uniprotkb:O15139|uniprotkb:Q5VW62|uniprotkb:Q6IPB5|uniprotkb:Q9UEC9|ensembl:ENSP00000356919|ensembl:ENSP00000505025|ensembl:ENSP00000505998 psi-mi:cr3l3_human(display_long)|uniprotkb:Transcription factor CREB-H(gene name synonym)|uniprotkb:CREB3L3(gene name)|psi-mi:CREB3L3(display_short)|uniprotkb:CREBH(gene name synonym)|uniprotkb:HYST1481(orf name) psi-mi:atf6a_human(display_long)|uniprotkb:Activating transcription factor 6 alpha(gene name synonym)|uniprotkb:ATF6(gene name)|psi-mi:ATF6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2006) pubmed:16469704|imex:IM-11834 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-852240|imex:IM-11834-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115996.1|refseq:NP_001258925.1|refseq:NP_001258926.1|refseq:NP_001258924.1|ensembl:ENSG00000060566(gene)|ensembl:ENST00000078445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002675"(positive regulation of acute inflammatory response)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029806|reactome:R-HSA-8874211|reactome:R-HSA-8963889 refseq:NP_031374.2|dip:DIP-29304N|ensembl:ENSG00000118217(gene)|ensembl:ENST00000367942(transcript)|ensembl:ENST00000681738(transcript)|ensembl:ENST00000681801(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903893"(positive regulation of ATF6-mediated unfolded protein response)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029801|mint:P18850|reactome:R-HSA-380994|reactome:R-HSA-381033|reactome:R-HSA-381183|go:"GO:0030968"(endoplasmic reticulum unfolded protein response) imex:IM-1408(imex secondary) - - agonist:interaction observed in the presence of Tm|delivery method:Q68CJ9 transfection|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/02/14 2014/10/16 rogid:axewrbgxxLtbhwgtdJ4haLjlr7w9606 rogid:mIU7Apng6rQ423SQnZTsceVSRus9606 intact-crc:0902C51B95CA6904|rigid:60YDTVpjDHWXGCgynwFHm9GHZJU false flag tag:n-n|binding-associated region:1-321 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)