#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9NRA8 uniprotkb:P06730 intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym) psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0428"(imaging technique) Koritzinsky et al. (2006) pubmed:16467844|imex:IM-11067|mint:MINT-5218322 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8068576|mint:MINT-1956046|imex:IM-11067-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1|mint:MINT-1956047(identity) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N|mint:MINT-1956053(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/05/24 2014/10/16 rogid:4A9mF81S/ePAraruTNYgovUdkT49606 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 intact-crc:34AD35DE113B16BF|rigid:Dc1h8DyCQXhYWB2PyiFTWMWOlMo false - - 1 1 psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification)