#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q28109 uniprotkb:P01859 intact:EBI-8061363|intact:MINT-1782646 intact:EBI-1044662|uniprotkb:A6NE66|ensembl:ENSP00000374987|ensembl:ENSP00000480351 psi-mi:q28109_bovin(display_long) psi-mi:ighg2_human(display_long)|uniprotkb:IGHG2(gene name)|psi-mi:IGHG2(display_short)|uniprotkb:Ig gamma-2 chain C region(gene name synonym)|uniprotkb:Ig gamma-2 chain C region DOT(gene name synonym)|uniprotkb:Ig gamma-2 chain C region TIL(gene name synonym)|uniprotkb:Ig gamma-2 chain C region ZIE(gene name synonym) psi-mi:"MI:0049"(filter binding) Zhang et al. (2006) pubmed:16457820|imex:IM-11484|mint:MINT-5218310 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8061355|mint:MINT-1782634|imex:IM-11484-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_001001138.1|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR036179|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|mint:MINT-1782635(identity) reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|rcsb pdb:4L4J|ensembl:ENSG00000211893(gene)|ensembl:ENSG00000274497(gene)|ensembl:ENST00000390545(transcript)|ensembl:ENST00000621803(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2QSC|rcsb pdb:4HAF|rcsb pdb:4HAG|mint:MINT-1782636(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|figure legend:F2|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/10 2014/10/16 rogid:qPASIvuhCwip71wKwNvhH3Ur4ns9913 rogid:EZkOg27Ga0FblVGpeMMQzW0s/xo9606 intact-crc:BC30D16E2023F2CD|rigid:bLEUBaQnAfLBXpk+kQ+Y+0AF8vY false binding-associated region:101-104(MINT-1782659) - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q28109 uniprotkb:P01859 intact:EBI-8061363|intact:MINT-1782646 intact:EBI-1044662|uniprotkb:A6NE66|ensembl:ENSP00000374987|ensembl:ENSP00000480351 psi-mi:q28109_bovin(display_long) psi-mi:ighg2_human(display_long)|uniprotkb:IGHG2(gene name)|psi-mi:IGHG2(display_short)|uniprotkb:Ig gamma-2 chain C region(gene name synonym)|uniprotkb:Ig gamma-2 chain C region DOT(gene name synonym)|uniprotkb:Ig gamma-2 chain C region TIL(gene name synonym)|uniprotkb:Ig gamma-2 chain C region ZIE(gene name synonym) psi-mi:"MI:0405"(competition binding) Zhang et al. (2006) pubmed:16457820|imex:IM-11484|mint:MINT-5218310 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8061393|mint:MINT-1782685|imex:IM-11484-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_001001138.1|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR036179|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|mint:MINT-1782686(identity) reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|rcsb pdb:4L4J|ensembl:ENSG00000211893(gene)|ensembl:ENSG00000274497(gene)|ensembl:ENST00000390545(transcript)|ensembl:ENST00000621803(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2QSC|rcsb pdb:4HAF|rcsb pdb:4HAG|mint:MINT-1782693(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/10 2014/10/16 rogid:qPASIvuhCwip71wKwNvhH3Ur4ns9913 rogid:EZkOg27Ga0FblVGpeMMQzW0s/xo9606 intact-crc:EB58F62A4F386129|rigid:bLEUBaQnAfLBXpk+kQ+Y+0AF8vY false - - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) uniprotkb:Q28109 uniprotkb:P01859 intact:EBI-8061363|intact:MINT-1782646 intact:EBI-1044662|uniprotkb:A6NE66|ensembl:ENSP00000374987|ensembl:ENSP00000480351 psi-mi:q28109_bovin(display_long) psi-mi:ighg2_human(display_long)|uniprotkb:IGHG2(gene name)|psi-mi:IGHG2(display_short)|uniprotkb:Ig gamma-2 chain C region(gene name synonym)|uniprotkb:Ig gamma-2 chain C region DOT(gene name synonym)|uniprotkb:Ig gamma-2 chain C region TIL(gene name synonym)|uniprotkb:Ig gamma-2 chain C region ZIE(gene name synonym) psi-mi:"MI:0401"(biochemical) Zhang et al. (2006) pubmed:16457820|imex:IM-11484|mint:MINT-5218310 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8061416|mint:MINT-1782705|imex:IM-11484-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_001001138.1|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR036179|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|mint:MINT-1782706(identity) reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|rcsb pdb:4L4J|ensembl:ENSG00000211893(gene)|ensembl:ENSG00000274497(gene)|ensembl:ENST00000390545(transcript)|ensembl:ENST00000621803(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2QSC|rcsb pdb:4HAF|rcsb pdb:4HAG|mint:MINT-1782711(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2006/03/10 2014/10/16 rogid:qPASIvuhCwip71wKwNvhH3Ur4ns9913 rogid:EZkOg27Ga0FblVGpeMMQzW0s/xo9606 intact-crc:D2827487B47A448E|rigid:bLEUBaQnAfLBXpk+kQ+Y+0AF8vY false - - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0113"(western blot)