#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8CDI2	uniprotkb:Q9JJ66	intact:EBI-8060482|uniprotkb:Q4G0C8|intact:MINT-2834647|uniprotkb:Q8R0R1	intact:EBI-2551389|ensembl:ENSMUSP00000006565|uniprotkb:Q3TGP1|uniprotkb:Q8BPG4|uniprotkb:Q99LK3	psi-mi:fbx43_mouse(display_long)|uniprotkb:Emi2(gene name synonym)|uniprotkb:Fbxo43(gene name)|psi-mi:Fbxo43(display_short)|uniprotkb:Endogenous meiotic inhibitor 2(gene name synonym)	psi-mi:cdc20_mouse(display_long)|uniprotkb:p55CDC(gene name synonym)|uniprotkb:Cdc20(gene name)|psi-mi:Cdc20(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shoji et al. (2006)	pubmed:16456547|imex:IM-11326|mint:MINT-5218307	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8060474|mint:MINT-2834643|imex:IM-11326-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q8CDI2|go:"GO:0005634"(nucleus)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|rcsb pdb:2RT9|rcsb pdb:5DMS|rcsb pdb:5DMV|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR044064|mint:MINT-2834644(identity)	ensembl:ENSMUSG00000006398(gene)|ensembl:ENSMUST00000006565(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051301"(cell division)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q9JJ66|reactome:R-MMU-141405|reactome:R-MMU-141430|reactome:R-MMU-141444|reactome:R-MMU-174048|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-176407|reactome:R-MMU-176408|go:"GO:1990757"(ubiquitin ligase activator activity)|reactome:R-MMU-176409|reactome:R-MMU-176417|reactome:R-MMU-179409|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-5689880|reactome:R-MMU-68877|reactome:R-MMU-9648025|reactome:R-MMU-983168|refseq:NP_075712.2|mint:MINT-2834645(identity)	-	comment:mint|function:"Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/24	2014/10/16	rogid:LPYVbN4vHn70cKpdw1ooCy1P8Bg10090	rogid:XQjzg7q4V+5Kxwe5BaIhOzExbaI10090	intact-crc:DB4DFCB2B2636B33|rigid:OnVRrt5R1vssDRR8qJe8/4YtSMY	false	tandem tag:?-?(MINT-2834654)	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8CDI2	uniprotkb:Q9JJ66	intact:EBI-8060482|uniprotkb:Q4G0C8|intact:MINT-2834647|uniprotkb:Q8R0R1	intact:EBI-2551389|ensembl:ENSMUSP00000006565|uniprotkb:Q3TGP1|uniprotkb:Q8BPG4|uniprotkb:Q99LK3	psi-mi:fbx43_mouse(display_long)|uniprotkb:Emi2(gene name synonym)|uniprotkb:Fbxo43(gene name)|psi-mi:Fbxo43(display_short)|uniprotkb:Endogenous meiotic inhibitor 2(gene name synonym)	psi-mi:cdc20_mouse(display_long)|uniprotkb:p55CDC(gene name synonym)|uniprotkb:Cdc20(gene name)|psi-mi:Cdc20(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Shoji et al. (2006)	pubmed:16456547|imex:IM-11326|mint:MINT-5218307	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8060520|mint:MINT-2834673|imex:IM-11326-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q8CDI2|go:"GO:0005634"(nucleus)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|rcsb pdb:2RT9|rcsb pdb:5DMS|rcsb pdb:5DMV|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR044064|mint:MINT-2834679(identity)	ensembl:ENSMUSG00000006398(gene)|ensembl:ENSMUST00000006565(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051301"(cell division)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q9JJ66|reactome:R-MMU-141405|reactome:R-MMU-141430|reactome:R-MMU-141444|reactome:R-MMU-174048|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-176407|reactome:R-MMU-176408|go:"GO:1990757"(ubiquitin ligase activator activity)|reactome:R-MMU-176409|reactome:R-MMU-176417|reactome:R-MMU-179409|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-5689880|reactome:R-MMU-68877|reactome:R-MMU-9648025|reactome:R-MMU-983168|refseq:NP_075712.2|mint:MINT-2834674(identity)	-	comment:mint|function:"Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/24	2014/10/16	rogid:LPYVbN4vHn70cKpdw1ooCy1P8Bg10090	rogid:XQjzg7q4V+5Kxwe5BaIhOzExbaI10090	intact-crc:5FA7EC092D501717|rigid:OnVRrt5R1vssDRR8qJe8/4YtSMY	false	tandem tag:?-?(MINT-2834684)	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)