#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P61289	uniprotkb:Q9Y6Q9	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066|uniprotkb:A4LAZ5|uniprotkb:Q0VF45	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2006)	pubmed:16439211|imex:IM-11830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-849837|imex:IM-11830-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151(gene)|ensembl:ENST00000371998(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035624"(receptor transactivation)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|dip:DIP-30876N	go:"GO:0005634"(nucleus)|imex:IM-1291(imex secondary)	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2006/02/08	2014/10/16	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606	intact-crc:870AF7B4C1C2374A|rigid:IeTLHHFBwFv791rGV5oXPWnQM5Y	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P61289	uniprotkb:Q9Y6Q9	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066|uniprotkb:A4LAZ5|uniprotkb:Q0VF45	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2006)	pubmed:16439211|imex:IM-11830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-849846|imex:IM-11830-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151(gene)|ensembl:ENST00000371998(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035624"(receptor transactivation)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|dip:DIP-30876N	imex:IM-1291(imex secondary)	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2006/02/08	2014/10/16	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606	intact-crc:594E1A306842485F|rigid:IeTLHHFBwFv791rGV5oXPWnQM5Y	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P61289	uniprotkb:Q9Y6Q9	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066|uniprotkb:A4LAZ5|uniprotkb:Q0VF45	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2006)	pubmed:16439211|imex:IM-11830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-849865|imex:IM-11830-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151(gene)|ensembl:ENST00000371998(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035624"(receptor transactivation)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|dip:DIP-30876N	imex:IM-1291(imex secondary)	-	-	delivery method:Q9Y6Q9 transient transfection|expression level:Q6UW15 endogenous|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/02/08	2014/10/16	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606	intact-crc:094B24A86F45A411|rigid:IeTLHHFBwFv791rGV5oXPWnQM5Y	false	-	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P61289	uniprotkb:Q9Y6Q9	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066|uniprotkb:A4LAZ5|uniprotkb:Q0VF45	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2006)	pubmed:16439211|imex:IM-11830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-849878|imex:IM-11830-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151(gene)|ensembl:ENST00000371998(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035624"(receptor transactivation)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|dip:DIP-30876N	imex:IM-1291(imex secondary)	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/08	2014/10/16	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606	intact-crc:1A1C7AD38D6CC151|rigid:IeTLHHFBwFv791rGV5oXPWnQM5Y	false	35s radiolabel:?-?	glutathione s tranferase tag:?-?|sufficient binding region:1081-1417	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61289	uniprotkb:Q9Y6Q9	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066|uniprotkb:A4LAZ5|uniprotkb:Q0VF45	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2006)	pubmed:16439211|imex:IM-11830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-849908|imex:IM-11830-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151(gene)|ensembl:ENST00000371998(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035624"(receptor transactivation)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|dip:DIP-30876N	imex:IM-1291(imex secondary)	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/08	2014/10/16	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606	intact-crc:6F9DAF7DFF7EADFF|rigid:IeTLHHFBwFv791rGV5oXPWnQM5Y	false	glutathione s tranferase tag:?-?	35s radiolabel:?-?|binding-associated region:1081-1417	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)