#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q13426	uniprotkb:Q9H9Q4	intact:EBI-717592|uniprotkb:Q9BS72|uniprotkb:Q9UP94|uniprotkb:A8K3X4|ensembl:ENSP00000342011|ensembl:ENSP00000421491	intact:EBI-847807|uniprotkb:B8ZZA4|uniprotkb:Q4ZFW7|uniprotkb:Q6IA64|uniprotkb:Q96JS9|ensembl:ENSP00000349313	psi-mi:xrcc4_human(display_long)|uniprotkb:X-ray repair cross-complementing protein 4(gene name synonym)|uniprotkb:XRCC4(gene name)|psi-mi:XRCC4(display_short)	psi-mi:nhej1_human(display_long)|uniprotkb:Protein cernunnos(gene name synonym)|uniprotkb:XRCC4-like factor(gene name synonym)|uniprotkb:NHEJ1(gene name)|psi-mi:NHEJ1(display_short)|uniprotkb:XLF(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Ahnesorg et al. (2006)	pubmed:16439205|imex:IM-11818	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-847811|imex:IM-11818-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003392.1|refseq:NP_071801.1|refseq:NP_072044.1|refseq:NP_001304941.1|refseq:NP_001304942.1|refseq:XP_011541928.1|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010165"(response to X-ray)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0070975"(FHA domain binding)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1990166"(protein localization to site of double-strand break)|interpro:IPR009089(DNA double-strand break repair and VJ recombination XRCC4, N-terminal)|interpro:IPR010585(DNA double-strand break repair and VJ recombination XRCC4)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR038051|mint:Q13426|rcsb pdb:1FU1|rcsb pdb:1IK9|rcsb pdb:3II6|rcsb pdb:3MUD|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|go:"GO:0005737"(cytoplasm)|rcsb pdb:3W03|rcsb pdb:4XA4|rcsb pdb:5CHX|rcsb pdb:5CJ0|rcsb pdb:5CJ4|rcsb pdb:5E50|rcsb pdb:5WJ7|rcsb pdb:5WLZ|rcsb pdb:6ABO|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7M3P|reactome:R-HSA-164843|reactome:R-HSA-3108214|reactome:R-HSA-5693571|ensembl:ENSG00000152422(gene)|ensembl:ENST00000338635(transcript)|ensembl:ENST00000511817(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-37957N	refseq:NP_079058.1|dip:DIP-37959N|ensembl:ENSG00000187736(gene)|ensembl:ENST00000356853(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007417"(central nervous system development)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0045027"(DNA end binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070419"(nonhomologous end joining complex)|interpro:IPR015381(XLF/Cernunnos)|interpro:IPR038051|mint:Q9H9Q4|rcsb pdb:2QM4|rcsb pdb:2R9A|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|rcsb pdb:3W03|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-5693571	imex:IM-188(imex secondary)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/02/03	2014/10/16	rogid:qWdX2yBKXcwYG7vQpss9MIaFWU89606	rogid:hnf1mGj+PBW/rU7H5eccVwr2eNU9606	intact-crc:EDFFDF07D8922539|rigid:CTZSVayZLdhZLqmzq9qSEPm15l4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13426	uniprotkb:Q7Z2E3	intact:EBI-717592|uniprotkb:Q9BS72|uniprotkb:Q9UP94|uniprotkb:A8K3X4|ensembl:ENSP00000342011|ensembl:ENSP00000421491	intact:EBI-847814|uniprotkb:A8MTN4|uniprotkb:Q5T781|uniprotkb:Q7Z2F3|uniprotkb:Q7Z336|uniprotkb:Q7Z5R5|uniprotkb:Q7Z6V7|uniprotkb:Q7Z6V8|uniprotkb:Q9NXM5|uniprotkb:Q0P662|uniprotkb:Q5T784|uniprotkb:D3DRK9|uniprotkb:D3DRL0|uniprotkb:Q5T782|uniprotkb:Q6JV81|uniprotkb:Q6JV82|uniprotkb:Q6JV85	psi-mi:xrcc4_human(display_long)|uniprotkb:X-ray repair cross-complementing protein 4(gene name synonym)|uniprotkb:XRCC4(gene name)|psi-mi:XRCC4(display_short)	psi-mi:aptx_human(display_long)|uniprotkb:Forkhead-associated domain histidine triad-like protein(gene name synonym)|uniprotkb:APTX(gene name)|psi-mi:APTX(display_short)|uniprotkb:AXA1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Ahnesorg et al. (2006)	pubmed:16439205|imex:IM-11818	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-847883|imex:IM-11818-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003392.1|refseq:NP_071801.1|refseq:NP_072044.1|refseq:NP_001304941.1|refseq:NP_001304942.1|refseq:XP_011541928.1|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010165"(response to X-ray)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0070975"(FHA domain binding)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1990166"(protein localization to site of double-strand break)|interpro:IPR009089(DNA double-strand break repair and VJ recombination XRCC4, N-terminal)|interpro:IPR010585(DNA double-strand break repair and VJ recombination XRCC4)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR038051|mint:Q13426|rcsb pdb:1FU1|rcsb pdb:1IK9|rcsb pdb:3II6|rcsb pdb:3MUD|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|go:"GO:0005737"(cytoplasm)|rcsb pdb:3W03|rcsb pdb:4XA4|rcsb pdb:5CHX|rcsb pdb:5CJ0|rcsb pdb:5CJ4|rcsb pdb:5E50|rcsb pdb:5WJ7|rcsb pdb:5WLZ|rcsb pdb:6ABO|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7M3P|reactome:R-HSA-164843|reactome:R-HSA-3108214|reactome:R-HSA-5693571|ensembl:ENSG00000152422(gene)|ensembl:ENST00000338635(transcript)|ensembl:ENST00000511817(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-37957N	refseq:XP_006716854.1|refseq:XP_006716855.1|refseq:NP_001182177.1|refseq:NP_001182178.1|refseq:NP_001182179.1|refseq:NP_001182180.1|refseq:NP_001182181.1|refseq:NP_001182183.1|refseq:NP_778239.1|refseq:NP_778243.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR008984(SMAD/FHA domain)|refseq:XP_016870326.1|interpro:IPR026963|interpro:IPR032566|interpro:IPR036265|refseq:XP_011516240.1|refseq:XP_011516241.1|mint:Q7Z2E3|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR041388|go:"GO:0000012"(single strand break repair)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006266"(DNA ligation)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008967"(phosphoglycolate phosphatase activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033699"(DNA 5'-adenosine monophosphate hydrolase activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0046403"(polynucleotide 3'-phosphatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0120108"(DNA-3'-diphospho-5'-guanosine diphosphatase)|go:"GO:1990165"(single-strand break-containing DNA binding)|rcsb pdb:3KT9|rcsb pdb:4NDF|rcsb pdb:4NDG|rcsb pdb:4NDH|rcsb pdb:4NDI|rcsb pdb:6CVO|rcsb pdb:6CVP|rcsb pdb:6CVQ|rcsb pdb:6CVR|rcsb pdb:6CVS|rcsb pdb:6CVT	imex:IM-185(imex secondary)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/02/03	2014/10/16	rogid:qWdX2yBKXcwYG7vQpss9MIaFWU89606	rogid:+F8ouBUeaA4oDe1S6zOGADQfCxQ9606	intact-crc:26726EA1FF8EF3C4|rigid:5QCJbW1vaTXme0yxPzW7FuVrdEo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H9Q4	uniprotkb:Q13426	intact:EBI-847807|uniprotkb:B8ZZA4|uniprotkb:Q4ZFW7|uniprotkb:Q6IA64|uniprotkb:Q96JS9|ensembl:ENSP00000349313	intact:EBI-717592|uniprotkb:Q9BS72|uniprotkb:Q9UP94|uniprotkb:A8K3X4|ensembl:ENSP00000342011|ensembl:ENSP00000421491	psi-mi:nhej1_human(display_long)|uniprotkb:Protein cernunnos(gene name synonym)|uniprotkb:XRCC4-like factor(gene name synonym)|uniprotkb:NHEJ1(gene name)|psi-mi:NHEJ1(display_short)|uniprotkb:XLF(gene name synonym)	psi-mi:xrcc4_human(display_long)|uniprotkb:X-ray repair cross-complementing protein 4(gene name synonym)|uniprotkb:XRCC4(gene name)|psi-mi:XRCC4(display_short)	psi-mi:"MI:0096"(pull down)	Ahnesorg et al. (2006)	pubmed:16439205|imex:IM-11818	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-847891|imex:IM-11818-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079058.1|dip:DIP-37959N|ensembl:ENSG00000187736(gene)|ensembl:ENST00000356853(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007417"(central nervous system development)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0045027"(DNA end binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070419"(nonhomologous end joining complex)|interpro:IPR015381(XLF/Cernunnos)|interpro:IPR038051|mint:Q9H9Q4|rcsb pdb:2QM4|rcsb pdb:2R9A|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|rcsb pdb:3W03|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-5693571	refseq:NP_003392.1|refseq:NP_071801.1|refseq:NP_072044.1|refseq:NP_001304941.1|refseq:NP_001304942.1|refseq:XP_011541928.1|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010165"(response to X-ray)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0070975"(FHA domain binding)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1990166"(protein localization to site of double-strand break)|interpro:IPR009089(DNA double-strand break repair and VJ recombination XRCC4, N-terminal)|interpro:IPR010585(DNA double-strand break repair and VJ recombination XRCC4)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR038051|mint:Q13426|rcsb pdb:1FU1|rcsb pdb:1IK9|rcsb pdb:3II6|rcsb pdb:3MUD|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|go:"GO:0005737"(cytoplasm)|rcsb pdb:3W03|rcsb pdb:4XA4|rcsb pdb:5CHX|rcsb pdb:5CJ0|rcsb pdb:5CJ4|rcsb pdb:5E50|rcsb pdb:5WJ7|rcsb pdb:5WLZ|rcsb pdb:6ABO|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7M3P|reactome:R-HSA-164843|reactome:R-HSA-3108214|reactome:R-HSA-5693571|ensembl:ENSG00000152422(gene)|ensembl:ENST00000338635(transcript)|ensembl:ENST00000511817(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-37957N	imex:IM-188(imex secondary)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/03	2014/10/16	rogid:hnf1mGj+PBW/rU7H5eccVwr2eNU9606	rogid:qWdX2yBKXcwYG7vQpss9MIaFWU89606	intact-crc:2F2A57CA3B28B60F|rigid:CTZSVayZLdhZLqmzq9qSEPm15l4	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49917	uniprotkb:Q9H9Q4	intact:EBI-847896|uniprotkb:Q8TEU5|uniprotkb:Q8IY66|ensembl:ENSP00000385955|ensembl:ENSP00000402030|ensembl:ENSP00000484288	intact:EBI-847807|uniprotkb:B8ZZA4|uniprotkb:Q4ZFW7|uniprotkb:Q6IA64|uniprotkb:Q96JS9|ensembl:ENSP00000349313	psi-mi:dnli4_human(display_long)|uniprotkb:DNA ligase IV(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 4(gene name synonym)|uniprotkb:LIG4(gene name)|psi-mi:LIG4(display_short)	psi-mi:nhej1_human(display_long)|uniprotkb:Protein cernunnos(gene name synonym)|uniprotkb:XRCC4-like factor(gene name synonym)|uniprotkb:NHEJ1(gene name)|psi-mi:NHEJ1(display_short)|uniprotkb:XLF(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ahnesorg et al. (2006)	pubmed:16439205|imex:IM-11818	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-847910|imex:IM-11818-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006720014.1|refseq:XP_006720015.1|refseq:NP_001091738.1|refseq:NP_002303.2|refseq:NP_996820.1|refseq:XP_016876060.1|refseq:XP_016876058.1|refseq:XP_016876059.1|dip:DIP-37958N|refseq:XP_011519393.1|refseq:XP_011519394.1|refseq:XP_005254113.1|refseq:XP_005254114.1|refseq:XP_005254115.1|refseq:NP_001317524.1|refseq:XP_016876062.1|ensembl:ENSG00000174405(gene)|ensembl:ENST00000405925(transcript)|ensembl:ENST00000442234(transcript)|ensembl:ENST00000611712(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003909"(DNA ligase activity)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006266"(DNA ligation)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007049"(cell cycle)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016874"(ligase activity)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045190"(isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051102"(DNA ligation involved in DNA recombination)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0075713"(establishment of integrated proviral latency)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:2001252"(positive regulation of chromosome organization)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR001357(BRCT)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR021536|interpro:IPR029710|interpro:IPR036420|interpro:IPR036599|interpro:IPR044125|mint:P49917|rcsb pdb:1IK9|rcsb pdb:2E2W|rcsb pdb:3II6|rcsb pdb:3VNN|rcsb pdb:3W1B|rcsb pdb:3W1G|rcsb pdb:3W5O|rcsb pdb:4HTO|rcsb pdb:4HTP|rcsb pdb:6BKF|rcsb pdb:6BKG|rcsb pdb:7D9K|rcsb pdb:7D9Y|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-5693571	refseq:NP_079058.1|dip:DIP-37959N|ensembl:ENSG00000187736(gene)|ensembl:ENST00000356853(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007417"(central nervous system development)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0045027"(DNA end binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070419"(nonhomologous end joining complex)|interpro:IPR015381(XLF/Cernunnos)|interpro:IPR038051|mint:Q9H9Q4|rcsb pdb:2QM4|rcsb pdb:2R9A|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|rcsb pdb:3W03|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-5693571	imex:IM-187(imex secondary)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/03	2014/10/16	rogid:ISugsd4sAk8gxR8n4GCk3ZkPijo9606	rogid:hnf1mGj+PBW/rU7H5eccVwr2eNU9606	intact-crc:BFDB005E743AC9F3|rigid:7dptgXGHjJYs8679bnCZ60oT5IE	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H9Q4	uniprotkb:Q13426	intact:EBI-847807|uniprotkb:B8ZZA4|uniprotkb:Q4ZFW7|uniprotkb:Q6IA64|uniprotkb:Q96JS9|ensembl:ENSP00000349313	intact:EBI-717592|uniprotkb:Q9BS72|uniprotkb:Q9UP94|uniprotkb:A8K3X4|ensembl:ENSP00000342011|ensembl:ENSP00000421491	psi-mi:nhej1_human(display_long)|uniprotkb:Protein cernunnos(gene name synonym)|uniprotkb:XRCC4-like factor(gene name synonym)|uniprotkb:NHEJ1(gene name)|psi-mi:NHEJ1(display_short)|uniprotkb:XLF(gene name synonym)	psi-mi:xrcc4_human(display_long)|uniprotkb:X-ray repair cross-complementing protein 4(gene name synonym)|uniprotkb:XRCC4(gene name)|psi-mi:XRCC4(display_short)	psi-mi:"MI:0019"(coimmunoprecipitation)	Ahnesorg et al. (2006)	pubmed:16439205|imex:IM-11818	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-847920|imex:IM-11818-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079058.1|dip:DIP-37959N|ensembl:ENSG00000187736(gene)|ensembl:ENST00000356853(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007417"(central nervous system development)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0045027"(DNA end binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070419"(nonhomologous end joining complex)|interpro:IPR015381(XLF/Cernunnos)|interpro:IPR038051|mint:Q9H9Q4|rcsb pdb:2QM4|rcsb pdb:2R9A|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|rcsb pdb:3W03|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-5693571	refseq:NP_003392.1|refseq:NP_071801.1|refseq:NP_072044.1|refseq:NP_001304941.1|refseq:NP_001304942.1|refseq:XP_011541928.1|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010165"(response to X-ray)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0070975"(FHA domain binding)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1990166"(protein localization to site of double-strand break)|interpro:IPR009089(DNA double-strand break repair and VJ recombination XRCC4, N-terminal)|interpro:IPR010585(DNA double-strand break repair and VJ recombination XRCC4)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR038051|mint:Q13426|rcsb pdb:1FU1|rcsb pdb:1IK9|rcsb pdb:3II6|rcsb pdb:3MUD|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|go:"GO:0005737"(cytoplasm)|rcsb pdb:3W03|rcsb pdb:4XA4|rcsb pdb:5CHX|rcsb pdb:5CJ0|rcsb pdb:5CJ4|rcsb pdb:5E50|rcsb pdb:5WJ7|rcsb pdb:5WLZ|rcsb pdb:6ABO|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7M3P|reactome:R-HSA-164843|reactome:R-HSA-3108214|reactome:R-HSA-5693571|ensembl:ENSG00000152422(gene)|ensembl:ENST00000338635(transcript)|ensembl:ENST00000511817(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-37957N	imex:IM-188(imex secondary)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/02/03	2014/10/16	rogid:hnf1mGj+PBW/rU7H5eccVwr2eNU9606	rogid:qWdX2yBKXcwYG7vQpss9MIaFWU89606	intact-crc:F78F4378608B0F8D|rigid:CTZSVayZLdhZLqmzq9qSEPm15l4	false	ha tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49917	uniprotkb:Q9H9Q4	intact:EBI-847896|uniprotkb:Q8TEU5|uniprotkb:Q8IY66|ensembl:ENSP00000385955|ensembl:ENSP00000402030|ensembl:ENSP00000484288	intact:EBI-847807|uniprotkb:B8ZZA4|uniprotkb:Q4ZFW7|uniprotkb:Q6IA64|uniprotkb:Q96JS9|ensembl:ENSP00000349313	psi-mi:dnli4_human(display_long)|uniprotkb:DNA ligase IV(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 4(gene name synonym)|uniprotkb:LIG4(gene name)|psi-mi:LIG4(display_short)	psi-mi:nhej1_human(display_long)|uniprotkb:Protein cernunnos(gene name synonym)|uniprotkb:XRCC4-like factor(gene name synonym)|uniprotkb:NHEJ1(gene name)|psi-mi:NHEJ1(display_short)|uniprotkb:XLF(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Ahnesorg et al. (2006)	pubmed:16439205|imex:IM-11818	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-847925|imex:IM-11818-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006720014.1|refseq:XP_006720015.1|refseq:NP_001091738.1|refseq:NP_002303.2|refseq:NP_996820.1|refseq:XP_016876060.1|refseq:XP_016876058.1|refseq:XP_016876059.1|dip:DIP-37958N|refseq:XP_011519393.1|refseq:XP_011519394.1|refseq:XP_005254113.1|refseq:XP_005254114.1|refseq:XP_005254115.1|refseq:NP_001317524.1|refseq:XP_016876062.1|ensembl:ENSG00000174405(gene)|ensembl:ENST00000405925(transcript)|ensembl:ENST00000442234(transcript)|ensembl:ENST00000611712(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003909"(DNA ligase activity)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006266"(DNA ligation)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007049"(cell cycle)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016874"(ligase activity)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045190"(isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051102"(DNA ligation involved in DNA recombination)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0075713"(establishment of integrated proviral latency)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:2001252"(positive regulation of chromosome organization)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR001357(BRCT)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR021536|interpro:IPR029710|interpro:IPR036420|interpro:IPR036599|interpro:IPR044125|mint:P49917|rcsb pdb:1IK9|rcsb pdb:2E2W|rcsb pdb:3II6|rcsb pdb:3VNN|rcsb pdb:3W1B|rcsb pdb:3W1G|rcsb pdb:3W5O|rcsb pdb:4HTO|rcsb pdb:4HTP|rcsb pdb:6BKF|rcsb pdb:6BKG|rcsb pdb:7D9K|rcsb pdb:7D9Y|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-5693571	refseq:NP_079058.1|dip:DIP-37959N|ensembl:ENSG00000187736(gene)|ensembl:ENST00000356853(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007417"(central nervous system development)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0045027"(DNA end binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070419"(nonhomologous end joining complex)|interpro:IPR015381(XLF/Cernunnos)|interpro:IPR038051|mint:Q9H9Q4|rcsb pdb:2QM4|rcsb pdb:2R9A|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|rcsb pdb:3W03|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-5693571	imex:IM-187(imex secondary)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/02/03	2014/10/16	rogid:ISugsd4sAk8gxR8n4GCk3ZkPijo9606	rogid:hnf1mGj+PBW/rU7H5eccVwr2eNU9606	intact-crc:CC0C8CE0A35EAA05|rigid:7dptgXGHjJYs8679bnCZ60oT5IE	false	-	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H9Q4	uniprotkb:Q9H9Q4	intact:EBI-847807|uniprotkb:B8ZZA4|uniprotkb:Q4ZFW7|uniprotkb:Q6IA64|uniprotkb:Q96JS9|ensembl:ENSP00000349313	intact:EBI-847807|uniprotkb:B8ZZA4|uniprotkb:Q4ZFW7|uniprotkb:Q6IA64|uniprotkb:Q96JS9|ensembl:ENSP00000349313	psi-mi:nhej1_human(display_long)|uniprotkb:Protein cernunnos(gene name synonym)|uniprotkb:XRCC4-like factor(gene name synonym)|uniprotkb:NHEJ1(gene name)|psi-mi:NHEJ1(display_short)|uniprotkb:XLF(gene name synonym)	psi-mi:nhej1_human(display_long)|uniprotkb:Protein cernunnos(gene name synonym)|uniprotkb:XRCC4-like factor(gene name synonym)|uniprotkb:NHEJ1(gene name)|psi-mi:NHEJ1(display_short)|uniprotkb:XLF(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Ahnesorg et al. (2006)	pubmed:16439205|imex:IM-11818	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-847945|imex:IM-11818-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079058.1|dip:DIP-37959N|ensembl:ENSG00000187736(gene)|ensembl:ENST00000356853(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007417"(central nervous system development)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0045027"(DNA end binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070419"(nonhomologous end joining complex)|interpro:IPR015381(XLF/Cernunnos)|interpro:IPR038051|mint:Q9H9Q4|rcsb pdb:2QM4|rcsb pdb:2R9A|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|rcsb pdb:3W03|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-5693571	refseq:NP_079058.1|dip:DIP-37959N|ensembl:ENSG00000187736(gene)|ensembl:ENST00000356853(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007417"(central nervous system development)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0045027"(DNA end binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070419"(nonhomologous end joining complex)|interpro:IPR015381(XLF/Cernunnos)|interpro:IPR038051|mint:Q9H9Q4|rcsb pdb:2QM4|rcsb pdb:2R9A|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|rcsb pdb:3W03|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-5693571	go:"GO:0042803"(protein homodimerization activity)|imex:IM-186(imex secondary)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/02/03	2014/10/16	rogid:hnf1mGj+PBW/rU7H5eccVwr2eNU9606	rogid:hnf1mGj+PBW/rU7H5eccVwr2eNU9606	intact-crc:CA8D64131F26E7AD|rigid:j5Ke+ZwFjTBZK2/P2J8a443uy8I	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H9Q4	uniprotkb:Q13426	intact:EBI-847807|uniprotkb:B8ZZA4|uniprotkb:Q4ZFW7|uniprotkb:Q6IA64|uniprotkb:Q96JS9|ensembl:ENSP00000349313	intact:EBI-717592|uniprotkb:Q9BS72|uniprotkb:Q9UP94|uniprotkb:A8K3X4|ensembl:ENSP00000342011|ensembl:ENSP00000421491	psi-mi:nhej1_human(display_long)|uniprotkb:Protein cernunnos(gene name synonym)|uniprotkb:XRCC4-like factor(gene name synonym)|uniprotkb:NHEJ1(gene name)|psi-mi:NHEJ1(display_short)|uniprotkb:XLF(gene name synonym)	psi-mi:xrcc4_human(display_long)|uniprotkb:X-ray repair cross-complementing protein 4(gene name synonym)|uniprotkb:XRCC4(gene name)|psi-mi:XRCC4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ahnesorg et al. (2006)	pubmed:16439205|imex:IM-11818	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-847936|imex:IM-11818-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079058.1|dip:DIP-37959N|ensembl:ENSG00000187736(gene)|ensembl:ENST00000356853(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007417"(central nervous system development)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0045027"(DNA end binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070419"(nonhomologous end joining complex)|interpro:IPR015381(XLF/Cernunnos)|interpro:IPR038051|mint:Q9H9Q4|rcsb pdb:2QM4|rcsb pdb:2R9A|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|rcsb pdb:3W03|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-5693571	refseq:NP_003392.1|refseq:NP_071801.1|refseq:NP_072044.1|refseq:NP_001304941.1|refseq:NP_001304942.1|refseq:XP_011541928.1|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010165"(response to X-ray)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0070975"(FHA domain binding)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1990166"(protein localization to site of double-strand break)|interpro:IPR009089(DNA double-strand break repair and VJ recombination XRCC4, N-terminal)|interpro:IPR010585(DNA double-strand break repair and VJ recombination XRCC4)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR038051|mint:Q13426|rcsb pdb:1FU1|rcsb pdb:1IK9|rcsb pdb:3II6|rcsb pdb:3MUD|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|go:"GO:0005737"(cytoplasm)|rcsb pdb:3W03|rcsb pdb:4XA4|rcsb pdb:5CHX|rcsb pdb:5CJ0|rcsb pdb:5CJ4|rcsb pdb:5E50|rcsb pdb:5WJ7|rcsb pdb:5WLZ|rcsb pdb:6ABO|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7M3P|reactome:R-HSA-164843|reactome:R-HSA-3108214|reactome:R-HSA-5693571|ensembl:ENSG00000152422(gene)|ensembl:ENST00000338635(transcript)|ensembl:ENST00000511817(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-37957N	imex:IM-188(imex secondary)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2006/02/03	2014/10/16	rogid:hnf1mGj+PBW/rU7H5eccVwr2eNU9606	rogid:qWdX2yBKXcwYG7vQpss9MIaFWU89606	intact-crc:E36F0CB50CB58E7C|rigid:CTZSVayZLdhZLqmzq9qSEPm15l4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49917	uniprotkb:Q9H9Q4	intact:EBI-847896|uniprotkb:Q8TEU5|uniprotkb:Q8IY66|ensembl:ENSP00000385955|ensembl:ENSP00000402030|ensembl:ENSP00000484288	intact:EBI-847807|uniprotkb:B8ZZA4|uniprotkb:Q4ZFW7|uniprotkb:Q6IA64|uniprotkb:Q96JS9|ensembl:ENSP00000349313	psi-mi:dnli4_human(display_long)|uniprotkb:DNA ligase IV(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 4(gene name synonym)|uniprotkb:LIG4(gene name)|psi-mi:LIG4(display_short)	psi-mi:nhej1_human(display_long)|uniprotkb:Protein cernunnos(gene name synonym)|uniprotkb:XRCC4-like factor(gene name synonym)|uniprotkb:NHEJ1(gene name)|psi-mi:NHEJ1(display_short)|uniprotkb:XLF(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ahnesorg et al. (2006)	pubmed:16439205|imex:IM-11818	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-847939|imex:IM-11818-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006720014.1|refseq:XP_006720015.1|refseq:NP_001091738.1|refseq:NP_002303.2|refseq:NP_996820.1|refseq:XP_016876060.1|refseq:XP_016876058.1|refseq:XP_016876059.1|dip:DIP-37958N|refseq:XP_011519393.1|refseq:XP_011519394.1|refseq:XP_005254113.1|refseq:XP_005254114.1|refseq:XP_005254115.1|refseq:NP_001317524.1|refseq:XP_016876062.1|ensembl:ENSG00000174405(gene)|ensembl:ENST00000405925(transcript)|ensembl:ENST00000442234(transcript)|ensembl:ENST00000611712(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003909"(DNA ligase activity)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006266"(DNA ligation)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007049"(cell cycle)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016874"(ligase activity)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045190"(isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051102"(DNA ligation involved in DNA recombination)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0075713"(establishment of integrated proviral latency)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:2001252"(positive regulation of chromosome organization)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR001357(BRCT)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR021536|interpro:IPR029710|interpro:IPR036420|interpro:IPR036599|interpro:IPR044125|mint:P49917|rcsb pdb:1IK9|rcsb pdb:2E2W|rcsb pdb:3II6|rcsb pdb:3VNN|rcsb pdb:3W1B|rcsb pdb:3W1G|rcsb pdb:3W5O|rcsb pdb:4HTO|rcsb pdb:4HTP|rcsb pdb:6BKF|rcsb pdb:6BKG|rcsb pdb:7D9K|rcsb pdb:7D9Y|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-5693571	refseq:NP_079058.1|dip:DIP-37959N|ensembl:ENSG00000187736(gene)|ensembl:ENST00000356853(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007417"(central nervous system development)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0045027"(DNA end binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070419"(nonhomologous end joining complex)|interpro:IPR015381(XLF/Cernunnos)|interpro:IPR038051|mint:Q9H9Q4|rcsb pdb:2QM4|rcsb pdb:2R9A|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|rcsb pdb:3W03|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-5693571	imex:IM-187(imex secondary)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2006/02/03	2014/10/16	rogid:ISugsd4sAk8gxR8n4GCk3ZkPijo9606	rogid:hnf1mGj+PBW/rU7H5eccVwr2eNU9606	intact-crc:3640ECEB8B143670|rigid:7dptgXGHjJYs8679bnCZ60oT5IE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H9Q4	uniprotkb:Q13426	intact:EBI-847807|uniprotkb:B8ZZA4|uniprotkb:Q4ZFW7|uniprotkb:Q6IA64|uniprotkb:Q96JS9|ensembl:ENSP00000349313	intact:EBI-717592|uniprotkb:Q9BS72|uniprotkb:Q9UP94|uniprotkb:A8K3X4|ensembl:ENSP00000342011|ensembl:ENSP00000421491	psi-mi:nhej1_human(display_long)|uniprotkb:Protein cernunnos(gene name synonym)|uniprotkb:XRCC4-like factor(gene name synonym)|uniprotkb:NHEJ1(gene name)|psi-mi:NHEJ1(display_short)|uniprotkb:XLF(gene name synonym)	psi-mi:xrcc4_human(display_long)|uniprotkb:X-ray repair cross-complementing protein 4(gene name synonym)|uniprotkb:XRCC4(gene name)|psi-mi:XRCC4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ahnesorg et al. (2006)	pubmed:16439205|imex:IM-11818	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-847942|imex:IM-11818-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079058.1|dip:DIP-37959N|ensembl:ENSG00000187736(gene)|ensembl:ENST00000356853(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007417"(central nervous system development)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0045027"(DNA end binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070419"(nonhomologous end joining complex)|interpro:IPR015381(XLF/Cernunnos)|interpro:IPR038051|mint:Q9H9Q4|rcsb pdb:2QM4|rcsb pdb:2R9A|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|rcsb pdb:3W03|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-5693571	refseq:NP_003392.1|refseq:NP_071801.1|refseq:NP_072044.1|refseq:NP_001304941.1|refseq:NP_001304942.1|refseq:XP_011541928.1|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010165"(response to X-ray)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0070975"(FHA domain binding)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1990166"(protein localization to site of double-strand break)|interpro:IPR009089(DNA double-strand break repair and VJ recombination XRCC4, N-terminal)|interpro:IPR010585(DNA double-strand break repair and VJ recombination XRCC4)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR038051|mint:Q13426|rcsb pdb:1FU1|rcsb pdb:1IK9|rcsb pdb:3II6|rcsb pdb:3MUD|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|go:"GO:0005737"(cytoplasm)|rcsb pdb:3W03|rcsb pdb:4XA4|rcsb pdb:5CHX|rcsb pdb:5CJ0|rcsb pdb:5CJ4|rcsb pdb:5E50|rcsb pdb:5WJ7|rcsb pdb:5WLZ|rcsb pdb:6ABO|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7M3P|reactome:R-HSA-164843|reactome:R-HSA-3108214|reactome:R-HSA-5693571|ensembl:ENSG00000152422(gene)|ensembl:ENST00000338635(transcript)|ensembl:ENST00000511817(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-37957N	imex:IM-188(imex secondary)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2006/02/03	2014/10/16	rogid:hnf1mGj+PBW/rU7H5eccVwr2eNU9606	rogid:qWdX2yBKXcwYG7vQpss9MIaFWU89606	intact-crc:32A098B216BC9DB0|rigid:CTZSVayZLdhZLqmzq9qSEPm15l4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H9Q4	uniprotkb:P49917	intact:EBI-847807|uniprotkb:B8ZZA4|uniprotkb:Q4ZFW7|uniprotkb:Q6IA64|uniprotkb:Q96JS9|ensembl:ENSP00000349313	intact:EBI-847896|uniprotkb:Q8TEU5|uniprotkb:Q8IY66|ensembl:ENSP00000385955|ensembl:ENSP00000402030|ensembl:ENSP00000484288	psi-mi:nhej1_human(display_long)|uniprotkb:Protein cernunnos(gene name synonym)|uniprotkb:XRCC4-like factor(gene name synonym)|uniprotkb:NHEJ1(gene name)|psi-mi:NHEJ1(display_short)|uniprotkb:XLF(gene name synonym)	psi-mi:dnli4_human(display_long)|uniprotkb:DNA ligase IV(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 4(gene name synonym)|uniprotkb:LIG4(gene name)|psi-mi:LIG4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ahnesorg et al. (2006)	pubmed:16439205|imex:IM-11818	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-847959|imex:IM-11818-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079058.1|dip:DIP-37959N|ensembl:ENSG00000187736(gene)|ensembl:ENST00000356853(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007417"(central nervous system development)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0045027"(DNA end binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070419"(nonhomologous end joining complex)|interpro:IPR015381(XLF/Cernunnos)|interpro:IPR038051|mint:Q9H9Q4|rcsb pdb:2QM4|rcsb pdb:2R9A|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|rcsb pdb:3W03|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-5693571	refseq:XP_006720014.1|refseq:XP_006720015.1|refseq:NP_001091738.1|refseq:NP_002303.2|refseq:NP_996820.1|refseq:XP_016876060.1|refseq:XP_016876058.1|refseq:XP_016876059.1|dip:DIP-37958N|refseq:XP_011519393.1|refseq:XP_011519394.1|refseq:XP_005254113.1|refseq:XP_005254114.1|refseq:XP_005254115.1|refseq:NP_001317524.1|refseq:XP_016876062.1|ensembl:ENSG00000174405(gene)|ensembl:ENST00000405925(transcript)|ensembl:ENST00000442234(transcript)|ensembl:ENST00000611712(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003909"(DNA ligase activity)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006266"(DNA ligation)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007049"(cell cycle)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016874"(ligase activity)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045190"(isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051102"(DNA ligation involved in DNA recombination)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0075713"(establishment of integrated proviral latency)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:2001252"(positive regulation of chromosome organization)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR001357(BRCT)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR021536|interpro:IPR029710|interpro:IPR036420|interpro:IPR036599|interpro:IPR044125|mint:P49917|rcsb pdb:1IK9|rcsb pdb:2E2W|rcsb pdb:3II6|rcsb pdb:3VNN|rcsb pdb:3W1B|rcsb pdb:3W1G|rcsb pdb:3W5O|rcsb pdb:4HTO|rcsb pdb:4HTP|rcsb pdb:6BKF|rcsb pdb:6BKG|rcsb pdb:7D9K|rcsb pdb:7D9Y|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-5693571	imex:IM-187(imex secondary)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-cls)|taxid:9606("Homo sapiens fibroblast cell line (GM03318)")	-	2006/02/03	2014/10/16	rogid:hnf1mGj+PBW/rU7H5eccVwr2eNU9606	rogid:ISugsd4sAk8gxR8n4GCk3ZkPijo9606	intact-crc:86E0D716522C7D67|rigid:7dptgXGHjJYs8679bnCZ60oT5IE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)